LOCUS       NZ_CP124548.1          27697 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP124548.1 Actinomyces israelii strain F0345 chromosome, complete
            genome.
ACCESSION   NZ_CP124548
VERSION     NZ_CP124548.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:17:25
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 119269
            Orig. end    :: 146966
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..264)
                     /locus_tag="ctg1_102"
                     /transl_table=11
                     /translation="MSEFTADGTDRTTTLKLSGLTCDHCVAHVTEELKALDGVKNVSVV
                     LSKGGQSVATVVSDVVLDDAALAEAIDEAGDYSLDAVERDVA"
     protocluster    1..27697
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[126605:137084]"
                     /cutoff="20000"
                     /detection_rule="((YcaO or TIGR03882) and ((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or PF07366 or PF06968 or PF04055) or
                     thiostrepton)"
                     /neighbourhood="10000"
                     /product="thiopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      7337..17815
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((YcaO or TIGR03882) and ((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or PF07366 or PF06968 or PF04055) or
                     thiostrepton)"
                     /neighbourhood="10000"
                     /product="thiopeptide"
                     /protocluster_number="1"
     cand_cluster    1..27697
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03882) and ((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or PF07366 or PF06968 or PF04055) or
                     thiostrepton)"
                     /kind="single"
                     /product="thiopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..27697
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="thiopeptide"
                     /region_number="1"
                     /rules="((YcaO or TIGR03882) and ((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or PF07366 or PF06968 or PF04055) or thiostrepton)"
                     /tool="antismash"
     PFAM_domain     complement(40..225)
                     /aSDomain="HMA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00403.28"
                     /description="Heavy-metal-associated domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_102_0001"
                     /evalue="1.00E-10"
                     /label="ctg1_102"
                     /locus_tag="ctg1_102"
                     /protein_end="75"
                     /protein_start="13"
                     /score="41.9"
                     /tool="antismash"
                     /translation="TLKLSGLTCDHCVAHVTEELKALDGVKNVSVVLSKGGQSVATVVS
                     DVVLDDAALAEAIDEAG"
     CDS             complement(289..570)
                     /locus_tag="ctg1_103"
                     /transl_table=11
                     /translation="MAGYTGTKDDYLKRLRRIEGQIRGISRMVEQDTYCIDVLTQVAAA
                     TKALQAVSLGLLEDHMSHCVIHAAQSSDAEGQAKIREASDAIARLVRS"
     PFAM_domain     complement(307..549)
                     /aSDomain="Trns_repr_metal"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02583.19"
                     /description="Metal-sensitive transcriptional repressor"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_103_0002"
                     /evalue="9.90E-32"
                     /label="ctg1_103"
                     /locus_tag="ctg1_103"
                     /protein_end="88"
                     /protein_start="7"
                     /score="109.3"
                     /tool="antismash"
                     /translation="KDDYLKRLRRIEGQIRGISRMVEQDTYCIDVLTQVAAATKALQAV
                     SLGLLEDHMSHCVIHAAQSSDAEGQAKIREASDAIA"
     CDS             2437..2688
                     /locus_tag="ctg1_104"
                     /transl_table=11
                     /translation="MGYGGGPGGPMGYGGAPGAPGQPAGSGLPAPMAVNPYAPPGVDGR
                     PGRARPPQSVGRGRNKGVGPYVGWIIFFLFLVIWHIVR"
     CDS             2770..3222
                     /locus_tag="ctg1_105"
                     /transl_table=11
                     /translation="MVETRSAGPWSRGRALLMLKRILWWAGLVLLLPGPAALYNEDAIY
                     GFFASLPPRLDTSTGDVDRFLLMLTLTEERILATLVAGFVCWALCAVLGFVVFLRESDR
                     PAPRRSAWRVVRRLTIVIVSTVFLLAGALVGLLCNIGIDLYYNPIP"
     CDS             complement(3285..4724)
                     /locus_tag="ctg1_106"
                     /transl_table=11
                     /translation="VGRYLTEPDQASKQPGDYFKAIRPGELERITGGGLKYFPIFQENS
                     RQLSDFTFENGARHAREAQAAAHRLGIPPTVIYFAVDMDVYEYQIDQVIEPYFRVIKEN
                     LGGGYGVGVYASRNTCSKIAKHGYTISSFVSDMSSGFSGNLGYPIPADWNYDQFAEISG
                     YAGKWDLDCVAHAGRVAACSSVLSSSSATPYPDPDPAKPEEDPLLAWSKKTERECLESL
                     GKASHPIRACRGFIGEFILEWLRKPEYWGDKYGGLWRLYTPEIPSPSELESARQICNGV
                     CKKQPAIKGLIPNRDIAHMAATAVGCLEWGIEEDNKEYGLGDLGGWPLDLLQIWGAYER
                     EADSSDLAAWLEKHLGGMHDGKGFGYEDVLADADAWLIARNMIHNPSSNALTNAMRDVF
                     KQSETHRIGRFYRERFGSRADNVVTAFKKVADGIDALGLKNIGCTLKKLLDAAHAKRLP
                     SEQEAEVLARAYAAFLSLPHR"
     misc_feature    complement(3378..3380)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     PFAM_domain     complement(4251..4724)
                     /aSDomain="DUF1906"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08924.13"
                     /description="Domain of unknown function (DUF1906)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_106_0003"
                     /evalue="1.30E-38"
                     /label="ctg1_106"
                     /locus_tag="ctg1_106"
                     /protein_end="158"
                     /protein_start="0"
                     /score="133.3"
                     /tool="antismash"
                     /translation="VGRYLTEPDQASKQPGDYFKAIRPGELERITGGGLKYFPIFQENS
                     RQLSDFTFENGARHAREAQAAAHRLGIPPTVIYFAVDMDVYEYQIDQVIEPYFRVIKEN
                     LGGGYGVGVYASRNTCSKIAKHGYTISSFVSDMSSGFSGNLGYPIPADWNYDQF"
     CDS             complement(4773..5309)
                     /locus_tag="ctg1_107"
                     /transl_table=11
                     /translation="MGIGGDSTVTVDIMRALLSMDQFVLLARYGGIPSIRSTQQKLNRE
                     YRAYVGIIPTDGLYGREMNTALIKTLQAVEGYSPDKATGNFGLGTRSKLVEIDAANAPT
                     YPKWVWLASVLLVCNGYPVRITQEWHGATDAGLDQFQKDYALPRNGKIDPTTWMSLMTS
                     KGDPDRPCDACDTRF"
     CDS             complement(6183..6887)
                     /gene_functions="regulatory (smcogs) SMCOG1016:LuxR family
                     DNA-binding response regulator (Score: 163.2; E-value:
                     8.3e-50)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_108"
                     /transl_table=11
                     /translation="MSPLTSLGPEHIGVALLDDDAMALSCLESYFAQAEDIRILLATRR
                     ADQLLKFLESNRVDVFITDIHMETMDGAQIAREVLRVSPSTGVILLTTVDTDDSLITGL
                     SAGASGFLLKSTPAEEILSAVRTVHSGAKVVAPMSTARLIDYVLASAHAEDGSVALSNR
                     ERDVLHMLCEGASNRRIASQLSISEATVKSHVSVLFTKTKTRSRLEIVVWAFRHGYAPA
                     LRCAPSGRAPTP"
     PFAM_domain     complement(6246..6413)
                     /aSDomain="GerE"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00196.21"
                     /description="Bacterial regulatory proteins, luxR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_108_0005"
                     /evalue="1.50E-17"
                     /label="ctg1_108"
                     /locus_tag="ctg1_108"
                     /protein_end="214"
                     /protein_start="158"
                     /score="63.0"
                     /tool="antismash"
                     /translation="ALSNRERDVLHMLCEGASNRRIASQLSISEATVKSHVSVLFTKTK
                     TRSRLEIVVWA"
     PFAM_domain     complement(6513..6848)
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_108_0004"
                     /evalue="7.00E-19"
                     /label="ctg1_108"
                     /locus_tag="ctg1_108"
                     /protein_end="125"
                     /protein_start="13"
                     /score="68.1"
                     /tool="antismash"
                     /translation="VALLDDDAMALSCLESYFAQAEDIRILLATRRADQLLKFLESNRV
                     DVFITDIHMETMDGAQIAREVLRVSPSTGVILLTTVDTDDSLITGLSAGASGFLLKSTP
                     AEEILSAV"
     CDS             7337..8713
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thiopeptide: YcaO"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_109"
                     /sec_met_domain="YcaO (E-value: 3.2e-63, bitscore: 212.0,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VYRSALKEPIAPSLARAASLESPVGLVSRTAELAQAPGEPAFSIW
                     TGFLGDLSAPLRSQTTWNHRVESGNIDGAGGAIDADLARHIAIVESLERYSSCSWEAEE
                     LIWDTPAGLGDAAIGPERWPACSPTELADPQCGLIPSDPRIPLRWVRGWSLTRGREVFV
                     PAVLVYLKFPVRSPSERFINMVSTGTTAHSDLREAVLGGLLEVVERDAIALTWLQRLRL
                     PEVVVDPADLDPEVAEYHRVGTSTELTVHLREATTDYGIPILYAVQTSEVDTELAQVVA
                     ATCDLDPQRALAKIYRELVSLRIALRSHARSPRAKEVTGQDMTVVGGALADAAPSMRHV
                     FDFLLEGPRPARRLADVGRPELRSTRGPSAGSAADPLARVVSALERAGSEAVVVDITTD
                     EARQVGMHVVKALVPEAVPLSFSHHARYLATPRLYDAPRAMGLTAHDEAGINPVRQPFA
                     "
     aSDomain        7559..8710
                     /aSDomain="TIGR03604"
                     /aSTool="tigrfam"
                     /description="TOMM_cyclo_SagD: thiazole/oxazole-forming
                     peptide maturase, SagD family component"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_109_0001"
                     /evalue="3.30E-118"
                     /identifier="TIGR03604"
                     /label="ctg1_109"
                     /locus_tag="ctg1_109"
                     /protein_end="458"
                     /protein_start="74"
                     /score="392.8"
                     /tool="antismash"
                     /translation="GGAIDADLARHIAIVESLERYSSCSWEAEELIWDTPAGLGDAAIG
                     PERWPACSPTELADPQCGLIPSDPRIPLRWVRGWSLTRGREVFVPAVLVYLKFPVRSPS
                     ERFINMVSTGTTAHSDLREAVLGGLLEVVERDAIALTWLQRLRLPEVVVDPADLDPEVA
                     EYHRVGTSTELTVHLREATTDYGIPILYAVQTSEVDTELAQVVAATCDLDPQRALAKIY
                     RELVSLRIALRSHARSPRAKEVTGQDMTVVGGALADAAPSMRHVFDFLLEGPRPARRLA
                     DVGRPELRSTRGPSAGSAADPLARVVSALERAGSEAVVVDITTDEARQVGMHVVKALVP
                     EAVPLSFSHHARYLATPRLYDAPRAMGLTAHDEAGINPVRQPFA"
     PFAM_domain     7565..8584
                     /aSDomain="YcaO"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02624.18"
                     /description="YcaO cyclodehydratase, ATP-ad Mg2+-binding"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_109_0006"
                     /evalue="1.00E-61"
                     /label="ctg1_109"
                     /locus_tag="ctg1_109"
                     /protein_end="416"
                     /protein_start="76"
                     /score="209.2"
                     /tool="antismash"
                     /translation="AIDADLARHIAIVESLERYSSCSWEAEELIWDTPAGLGDAAIGPE
                     RWPACSPTELADPQCGLIPSDPRIPLRWVRGWSLTRGREVFVPAVLVYLKFPVRSPSER
                     FINMVSTGTTAHSDLREAVLGGLLEVVERDAIALTWLQRLRLPEVVVDPADLDPEVAEY
                     HRVGTSTELTVHLREATTDYGIPILYAVQTSEVDTELAQVVAATCDLDPQRALAKIYRE
                     LVSLRIALRSHARSPRAKEVTGQDMTVVGGALADAAPSMRHVFDFLLEGPRPARRLADV
                     GRPELRSTRGPSAGSAADPLARVVSALERAGSEAVVVDITTDEARQVGMHVVKALVPEA
                     "
     CDS             8736..9398
                     /locus_tag="ctg1_110"
                     /transl_table=11
                     /translation="MSTSTASTAAQRPVTAYLPQGRFGHAVVERLVGPQDAVLPVDHGL
                     VYASVPYADRLVMVADADRTALREALDEVSFTRSVPSLGLELTPTELRCGPLVVPGRTA
                     CYSCCARRRRQHGYRPLPDDVEPLPQGYARHHVVIAAGLVALALSTLAAPAAGAGSGGA
                     DNDSELGGQVWTVDLVSGLTSLARTVATDRCRTCSGRYAARRDGVPALAALLPERVI"
     aSDomain        8982..9347
                     /aSDomain="TIGR03882"
                     /aSTool="tigrfam"
                     /description="cyclo_dehyd_2: bacteriocin biosynthesis
                     cyclodehydratase domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_110_0002"
                     /evalue="8.70E-11"
                     /identifier="TIGR03882"
                     /label="ctg1_110"
                     /locus_tag="ctg1_110"
                     /protein_end="204"
                     /protein_start="82"
                     /score="40.3"
                     /tool="antismash"
                     /translation="LGLELTPTELRCGPLVVPGRTACYSCCARRRRQHGYRPLPDDVEP
                     LPQGYARHHVVIAAGLVALALSTLAAPAAGAGSGGADNDSELGGQVWTVDLVSGLTSLA
                     RTVATDRCRTCSGRYAAR"
     CDS             9399..11564
                     /locus_tag="ctg1_111"
                     /transl_table=11
                     /translation="VATDTGTRAAGAAAQAAEPSSAAPAAQGMRAADVGRAARQDLQFR
                     IPRRPVVRRGVRMRREDDTWVLDGGRKSQVLGGAFARDHLGALLEACDGSRTLDQIGET
                     TGIGPNGAFEAVSLLWTGGIVEEGDTDPLPDPQPAPELACLLSRLGDSTGVNDSWQDAA
                     RRLSAARVAVMGDADLAGELVGALDPTLGARAAGAEEGDTLAVVVETAGSGAARGAAER
                     CWALGVPLLRVRAEHEAVTVGPYIDPSFSPCLECATAGEPGAGTTPGPSRRDLAVGLAA
                     RAVAALIARATTTHLPGDSRRIDLETFTHTDHPVTTRPGCPVCSVAGRPGAPDGARELD
                     GAEEPGGGHESGGSAGAAEPPVPVAPTAPVGARYEQAVAIPPAAFVDSKGHQQHYKPSN
                     LRLQREFRDWPTCPRTPLPDADLERLERPWPVGAGRGASAAMPGSNGSDGGAGAPAGAA
                     GRGGDPGASAESTAPGLSTGRPTLAELATVLALAVGVREPLRPQPQGADPSADAPKLRR
                     WTAAGGNIGSVTAYVLVPGGAPAAAGVGSDTGLAAGAGASAETAGAGPAGATAAARPIG
                     SADGADTAAGADPSAPLAPGVYTYIERDHALARVAPPPEAPAVPDGAGARLVLTGNVDK
                     LSKKYMSFGLRLAVQDCGCSLEVVRLVARCLGLPLRARARWDERELASAIGTDPRREPV
                     VAVVDLGAPGDSQVPAGSGDSGGRRAH"
     aSDomain        10083..10391
                     /aSDomain="TIGR03882"
                     /aSTool="tigrfam"
                     /description="cyclo_dehyd_2: bacteriocin biosynthesis
                     cyclodehydratase domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_111_0003"
                     /evalue="4.00E-11"
                     /identifier="TIGR03882"
                     /label="ctg1_111"
                     /locus_tag="ctg1_111"
                     /protein_end="331"
                     /protein_start="228"
                     /score="41.4"
                     /tool="antismash"
                     /translation="PLLRVRAEHEAVTVGPYIDPSFSPCLECATAGEPGAGTTPGPSRR
                     DLAVGLAARAVAALIARATTTHLPGDSRRIDLETFTHTDHPVTTRPGCPVCSVAGRPG"
     CDS             11554..12300
                     /locus_tag="ctg1_112"
                     /transl_table=11
                     /translation="VRTDYMILREIVEGFSDPQAAPTSDGLAARRPRRPLACELADVPD
                     PREGGPHPHGSPGYPHDLRQTFERRSSTTDYAPEPLDAAPLLADVRAALVEDAEDWGED
                     AGVGSLEPFVLLLRPRGGRPGVYRVRPDGVDLLGDPPSPEEIEGMTVQKEFARAGAIVS
                     VAADLDQADAWAGAHGYRHAMTRAAAVIYSVHLRSAARGLTGTVFAGLSPSAVRHLLDS
                     DGVSRHQMLAVTIAAPAAPARAAPSP"
     CDS             12511..12708
                     /locus_tag="ctg1_113"
                     /transl_table=11
                     /translation="MRLLRCVRVVPVLRGLLVVPVLRGLLLVPVLRRVRLDVVLLTPSR
                     RRAGGAMPSARRRPRHREPT"
     CDS             12724..13914
                     /locus_tag="ctg1_114"
                     /transl_table=11
                     /translation="MTMTTSPARTPGGDVPRLRRGVTLIVGMDDQPMLFDSTSGAYHRL
                     GKAAAFIVNQFDGSRSLPTIIDQLPQQIDDAGRQRITRLVEYLRSKSLLEGGAPPRVVP
                     QERVRKRADGRHVAPPHVGKHEQIHPPRWSGNWMLPRFMLIRSYRRAVAPVAAALHHLP
                     ARTLGWLFVFAAAGGYAAGVESLIHLSGGPRPAVSVYFIAVAIQLVSIVGHESWHAIVA
                     GYLGTPVRGLGVAFMFWVLPIAYVDRTDSYRVRSKLGRAMLAFAGICSDGVVCGVEAAV
                     AAASTGTVRQVALTLCAFQLTMLVTNLNPLTQSDGVATVEALTGSVNLRGRSMLVLRCA
                     LTRTPLPPALARMRLAARGGYFLYGLACALLSVVGTVFGVIWLGFMVVGIVRGVLA"
     CDS             13911..16763
                     /locus_tag="ctg1_115"
                     /transl_table=11
                     /translation="MTRIDSGAGAQAAAGWAGPPTPVGLAGSAAVRSAISGSAGSAPPS
                     SGPAAARATGQAPPGPAAAPAASGRSPAPAGPAATAGPPGPATAAQDGPAAAPASAGPT
                     AAPAALLPALARLGGLPESAVPAPEDALIGALDRLRRLEKDMAQAGDRLLDPLYRLIPD
                     LERDERRAVLHAKRRVFQGRVSGLTPRVRGSLPADVGAMLSAWDDLVAQRHAEHARLEA
                     AVTADLDRSRAVLAAGLDDADYLRAVAIAAPALVAALTRRGRRLDDSRVLRTLYSLATR
                     TALKASPFAGLTTVSEAGRPARGRRRCTVALHLAHGILSTTARDLDPDGLLRLEAAPVR
                     DVVGPDEGEGEPTLAVVAEHDYADGLVFRREEVQPARWLAVAHDRLTGGRSDAAPVSVS
                     EAAGLVGGRAPHLRLRRLLASGAVRPHAPWPRGEDPFPALTATLSDAQRRAWGEDLERL
                     QRLGRIVAVEDGPGRAELLTDVQRLARRIFPDGELGGRPSGLLYEDCESRGQWADPMEV
                     AGLRHDIETLAGLVDPWVTRSHIYDLMVRRYVARYGRGGVCEDPLAFVMALAHAPDGDS
                     EMLGAAAQDMSAGPDPERAAMPGGVSASPRHMGAYLQPVGGPEALGTGPGAPGASVALG
                     APGASSRAPGAGPGAPRASQGLTVVNAFTNGNGALQARFHRLLGRGYRARLAQGIRAAW
                     GVERVLEIQAATDCNTAQAASCGVLTPLGLPGEPAAPDAVALSSLRLAHDPRTDTLFLA
                     DAHGPVGLAYLGLIPQYRLGGYLSWLVLLSDPWARLAPLADHWNSRRLEMTGPLPDAAV
                     HAPRVTHGRLVTRRESWTFPAGQVTGLLDRDLAATLLRVADLREQWGIPAEVYVHQHLG
                     ARAEPGATADEHKPRYVDLRSPVSLLALRGWIDSAAEHLSLVEALPARDELAGTTPAGE
                     PTVLEYLVGVQWPKSEGDVR"
     CDS             16760..17815
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thiopeptide: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_116"
                     /sec_met_domain="Lant_dehydr_C (E-value: 2.5e-23, bitscore:
                     80.7, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VTAVRERDDVGGGPTAGGVAGGSETTAAAVGPGAGLAGAGSGSGL
                     GAGQAGASTGPGPAEDHPAAAVGPGAAEDRQVDWLYARIYCGGGDDTDALLPGIARWVD
                     EARADWPILSMHFLRFIDLRGHHVRLRLQADPDALDELFERLDVLDATARRARVRVLER
                     LVPDPMTAAGGTDGRAGVACSVYGPEYDKYGGPAGVEEAERHFDVSSRWCLDNRVWTAP
                     RPLPRVALAARFLAHAAAVGVLPPAELLGAHLRTWGSRLPERLRDGAALGAVVRQVLGC
                     RLEEVPGWARADELTGRLADDAGRTVRRIGAGPGGRRALDVLHMDANRFGVNPAEECVA
                     GVCARYLLGAG"
     PFAM_domain     16994..17776
                     /aSDomain="Lant_dehydr_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14028.8"
                     /description="Lantibiotic biosynthesis dehydratase C-term"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_116_0007"
                     /evalue="1.50E-22"
                     /label="ctg1_116"
                     /locus_tag="ctg1_116"
                     /protein_end="339"
                     /protein_start="78"
                     /score="80.8"
                     /tool="antismash"
                     /translation="WLYARIYCGGGDDTDALLPGIARWVDEARADWPILSMHFLRFIDL
                     RGHHVRLRLQADPDALDELFERLDVLDATARRARVRVLERLVPDPMTAAGGTDGRAGVA
                     CSVYGPEYDKYGGPAGVEEAERHFDVSSRWCLDNRVWTAPRPLPRVALAARFLAHAAAV
                     GVLPPAELLGAHLRTWGSRLPERLRDGAALGAVVRQVLGCRLEEVPGWARADELTGRLA
                     DDAGRTVRRIGAGPGGRRALDVLHMDANRFGVNPAEECV"
     CDS             complement(17975..19420)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1063:argininosuccinate lyase/adenylosuccinate lyase
                     (Score: 73.8; E-value: 2.3e-22)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_117"
                     /transl_table=11
                     /translation="MVDLSAVSPAIALGPLDGRYRAVAAPLVNHLSEAALNRARLRVEV
                     EWLIHLTDLGVLPGAPGLSDSEKAYLRGVVEGFGAEEIAELAEIEAVTRHDVKAVEYLL
                     KRRLDAAAQAPGVRAADGAPTVLPGVGEIVHIFCTSEDINNLAYALTVRAAVQEIWLPA
                     ARGLVADLAALARGQAGTPMLSRTHGQSATPTTLGKELAVLAHRLRRQVRRVEGAEYLG
                     KINGATGTYGAHVVAVPGADWESVARGFVESLGLTWNPLTTQIESHDWQAELYSDIARF
                     NRIAHNLATDAWTYISLGYFRQRLSAQGSTGSSTMPHKVNPIRFENGEANLEISCALLD
                     TLAATLVTSRLQRDLTDSTTQRNIGVALGHSLLAIDNIRRGLAGLNVDRARLAEDLDTA
                     WEVLGEPVQQAMRAAAVAGARGMADPYERLRELTRGRRITPEAMREFISGLGMPDDVEG
                     RLLALTPAAYTGLAEQLVAHLDD"
     PFAM_domain     complement(18014..18376)
                     /aSDomain="ASL_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08328.13"
                     /description="Adenylosuccinate lyase C-terminal"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_117_0009"
                     /evalue="2.20E-42"
                     /label="ctg1_117"
                     /locus_tag="ctg1_117"
                     /protein_end="469"
                     /protein_start="348"
                     /score="143.8"
                     /tool="antismash"
                     /translation="SRLQRDLTDSTTQRNIGVALGHSLLAIDNIRRGLAGLNVDRARLA
                     EDLDTAWEVLGEPVQQAMRAAAVAGARGMADPYERLRELTRGRRITPEAMREFISGLGM
                     PDDVEGRLLALTPAAYT"
     PFAM_domain     complement(18437..19366)
                     /aSDomain="Lyase_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00206.22"
                     /description="Lyase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_117_0008"
                     /evalue="1.70E-40"
                     /label="ctg1_117"
                     /locus_tag="ctg1_117"
                     /protein_end="328"
                     /protein_start="18"
                     /score="139.4"
                     /tool="antismash"
                     /translation="RYRAVAAPLVNHLSEAALNRARLRVEVEWLIHLTDLGVLPGAPGL
                     SDSEKAYLRGVVEGFGAEEIAELAEIEAVTRHDVKAVEYLLKRRLDAAAQAPGVRAADG
                     APTVLPGVGEIVHIFCTSEDINNLAYALTVRAAVQEIWLPAARGLVADLAALARGQAGT
                     PMLSRTHGQSATPTTLGKELAVLAHRLRRQVRRVEGAEYLGKINGATGTYGAHVVAVPG
                     ADWESVARGFVESLGLTWNPLTTQIESHDWQAELYSDIARFNRIAHNLATDAWTYISLG
                     YFRQRLSAQGSTGSSTMPHKVNPIRFENG"
     CDS             19788..19937
                     /locus_tag="ctg1_118"
                     /transl_table=11
                     /translation="MVERAEETVREWLSQWRQARLSSVVTGHAVGENEAKLKRARKQVS
                     DGKT"
     CDS             complement(19971..20660)
                     /locus_tag="ctg1_119"
                     /transl_table=11
                     /translation="VALVTYKSFQPHAKVTGFDGEQWMTWPDYIGLGWKVTQERMKADW
                     KGIWDYALPHVRATEEEVARTEETLGFRLPESYRGFLLASNGWPCFYQDMTIFSTDDLL
                     GGPLYDAGRIPLDLPECVESMAIDGVVAADYFTVAASETQNDVALLGRPGTPAEGAVAW
                     WGGEVMDRYKDFLEYYLSMLEYNKLDIEDIREKDGPKPDGVIHAVLGDNPYDDGVIILP
                     RSAAERT"
     PFAM_domain     complement(20373..20489)
                     /aSDomain="SMI1_KNR4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09346.12"
                     /description="SMI1 / KNR4 family (SUKH-1)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_119_0010"
                     /evalue="6.20E-06"
                     /label="ctg1_119"
                     /locus_tag="ctg1_119"
                     /protein_end="96"
                     /protein_start="57"
                     /score="26.7"
                     /tool="antismash"
                     /translation="ATEEEVARTEETLGFRLPESYRGFLLASNGWPCFYQDMT"
     CDS             complement(20819..21433)
                     /locus_tag="ctg1_120"
                     /transl_table=11
                     /translation="MIDMDAVNREIEAGRAELAASDKAILTLGTRRRIWEAMLDPQDDE
                     ASYRHRIELKMTCVRHVQHLWDRAFPGDSRVEEMLTLAQELINQQADPKQSQIHAESFL
                     VHVLDKTTEADFAAKTATLVAEGVSHAVISACYRNPDYNIADDETDDDELLPDTLEPSY
                     CCAGAAAHAPNWMPIEKTDVPARRAFWTWYLDEAIPQVLAN"
     PFAM_domain     complement(20837..21403)
                     /aSDomain="Imm5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14423.8"
                     /description="Immunity protein Imm5"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_120_0011"
                     /evalue="5.00E-29"
                     /label="ctg1_120"
                     /locus_tag="ctg1_120"
                     /protein_end="199"
                     /protein_start="10"
                     /score="101.8"
                     /tool="antismash"
                     /translation="IEAGRAELAASDKAILTLGTRRRIWEAMLDPQDDEASYRHRIELK
                     MTCVRHVQHLWDRAFPGDSRVEEMLTLAQELINQQADPKQSQIHAESFLVHVLDKTTEA
                     DFAAKTATLVAEGVSHAVISACYRNPDYNIADDETDDDELLPDTLEPSYCCAGAAAHAP
                     NWMPIEKTDVPARRAFWTWYLDEAIP"
     CDS             complement(21510..21731)
                     /locus_tag="ctg1_121"
                     /transl_table=11
                     /translation="MRDNGVPGQYYASHAERQESITAKEPAIGVAKELCDDCPGCFSRL
                     AQHEGRCWYVTDPDGTWIFYPDGTVVKP"
     CDS             complement(22599..24230)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075:alkaline serine protease, subtilase family
                     (Score: 235.5; E-value: 2.4e-71)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_122"
                     /sec_met_domain="Peptidase_S8 (E-value: 2.2e-52, bitscore:
                     175.7, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTVSRRRPALLALLCAFSLALTCVVSACSSSGSSTSGSGEAPAP
                     ASPAATAAAASSDRFVITWAKGSEAASLIDSVDAYGVDIIGSLPQKDQDALRAAAEQAS
                     VVVEQATAHVGGLTTVKLSEALTPEKSRTFIDALTSSDSVETAEPELRVTALDTSAGTP
                     NDEYFGYQWGLTAERHGVNATSAWSQSTGRGATVAVLDTGILPDHPDIGGQLLPGYDFI
                     SDSWIAGDDDGRDDDPTDMGDGVVANACGNGNKETKSTWHGSHVAGIIAASTDNSTGVA
                     GVAPDAKILPVRVLGRCGGGTDLIDALTWASGGSVKGAPDNANPAQVINLSLGGSGTCP
                     AYLQKAIDDAVDRGSIIVASAGNEDQDVSGVSPGGCENVITVGASNGNGARSFYSNYGT
                     GVEVSAPGGDPDVDSGILSLSQQSAPDSPPYVFMAGTSQAAPHVAGTVALLKSVDPGLT
                     TAKATTVLQDASQPLTSCDRDACGAGIVDAAAAVTALSSEQSPGGAPTEDPGPGEADAG
                     DGQGDGDSGGLRRNLGDLWDRISGDR"
     PFAM_domain     complement(22821..23657)
                     /aSDomain="Peptidase_S8"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00082.24"
                     /description="Subtilase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_122_0012"
                     /evalue="3.00E-55"
                     /label="ctg1_122"
                     /locus_tag="ctg1_122"
                     /protein_end="470"
                     /protein_start="191"
                     /score="187.6"
                     /tool="antismash"
                     /translation="GRGATVAVLDTGILPDHPDIGGQLLPGYDFISDSWIAGDDDGRDD
                     DPTDMGDGVVANACGNGNKETKSTWHGSHVAGIIAASTDNSTGVAGVAPDAKILPVRVL
                     GRCGGGTDLIDALTWASGGSVKGAPDNANPAQVINLSLGGSGTCPAYLQKAIDDAVDRG
                     SIIVASAGNEDQDVSGVSPGGCENVITVGASNGNGARSFYSNYGTGVEVSAPGGDPDVD
                     SGILSLSQQSAPDSPPYVFMAGTSQAAPHVAGTVALLKSVDPGLTTAKATTVLQDAS"
     CDS             complement(24493..25965)
                     /locus_tag="ctg1_123"
                     /transl_table=11
                     /translation="VRPGRRRHLIGSGLSRKAVQAQAYWIQGRAMGPDPGPGHGAGNEG
                     RRRYPRAMTNPHAVDPSWVAARNAALLADPAARVAGNAVATTDVERLTLDRAILTSIDT
                     SVSDLIPDAAVTDQKHSGRCWAFAGLNVLRAALMRELNLESVELSQSFVYFYDKLEKAA
                     AFLARAVGDAERPLDDREVADSLRDPIGDGGWWPEFARLVAKYGMVPHYAMPDADSATS
                     SEAMNDHLATLLRRTVLRLRAAAAAGEELEPIRAAALADVHRVLVIHLGAPPAEFVWQY
                     RDRGKVFHRVGALTPVEFARRYVSGLEEFVVVAHDPRPEIPLNTRFGIDRTDLMVGEPT
                     QEHVTAELGVLKAAAVAAIQDGEPVWFACDVAKQRDKESGVWDAALHDYEGLYGVKLSM
                     TKAERLVARESALTHAMCLTGVDLVDGAPRRWRVENSWGDKVGEKGFHTMNDSWFDEYV
                     YQVVVRARRLPPEVRAALDAGPIILPSWDPMA"
     PFAM_domain     complement(24496..25764)
                     /aSDomain="Peptidase_C1_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03051.17"
                     /description="Peptidase C1-like family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_123_0013"
                     /evalue="1.90E-133"
                     /label="ctg1_123"
                     /locus_tag="ctg1_123"
                     /protein_end="490"
                     /protein_start="67"
                     /score="445.6"
                     /tool="antismash"
                     /translation="NAALLADPAARVAGNAVATTDVERLTLDRAILTSIDTSVSDLIPD
                     AAVTDQKHSGRCWAFAGLNVLRAALMRELNLESVELSQSFVYFYDKLEKAAAFLARAVG
                     DAERPLDDREVADSLRDPIGDGGWWPEFARLVAKYGMVPHYAMPDADSATSSEAMNDHL
                     ATLLRRTVLRLRAAAAAGEELEPIRAAALADVHRVLVIHLGAPPAEFVWQYRDRGKVFH
                     RVGALTPVEFARRYVSGLEEFVVVAHDPRPEIPLNTRFGIDRTDLMVGEPTQEHVTAEL
                     GVLKAAAVAAIQDGEPVWFACDVAKQRDKESGVWDAALHDYEGLYGVKLSMTKAERLVA
                     RESALTHAMCLTGVDLVDGAPRRWRVENSWGDKVGEKGFHTMNDSWFDEYVYQVVVRAR
                     RLPPEVRAALDAGPIILPSWDPMA"
     CDS             26076..26978
                     /locus_tag="ctg1_124"
                     /transl_table=11
                     /translation="MGLFSDWRAFHRAIRAHGGGLRILKEAARDLASLKEPMEGVALPE
                     GAVEVVAPEGAVSTEDVDRDFETECWGALDALAEAGGGTVVAMGMGGERLALLLEHLLP
                     DYRAGLDVVAVEERGPAAASARERLGPLGARVEERADAGSRLPLADGGARLVMNRLKAL
                     SVPDVVRVLAPGGLLITQQVDDAGAPGTPDIPVASEVPGIPGTRGRLDARASRPSVRLR
                     AMTAALSEAGLIVESTSQWSRAVDVDSADELAADWGAVHPGAPGPDRAAVLARIREESG
                     GGPVLLVARRFCIRARRPS"
     CDS             complement(27077..27697)
                     /gene_functions="regulatory (smcogs) SMCOG1135:MarR family
                     transcriptional regulator (Score: 80.5; E-value: 1.4e-24)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_125"
                     /transl_table=11
                     /translation="MTTTARTPHEAPRTPPKEYEGWPLEAPRLPEGADRAVELSPLLAE
                     VVAGAPWTDADSMSDRVAGIVATTTVGALGGLLRRLRDRYAEREWGMSSSRVELLMLLA
                     RSGSPTMSELARTLDVTPRAVTRLVDGLEADGYVVRERQADDARVIRVRCTPEVLDRVA
                     RAAQAHLSQLLALCEGVDGDDLRTAVRVLQRISARARTELGLT"
     PFAM_domain     complement(27251..27421)
                     /aSDomain="MarR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01047.24"
                     /description="MarR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_125_0014"
                     /evalue="4.80E-12"
                     /label="ctg1_125"
                     /locus_tag="ctg1_125"
                     /protein_end="149"
                     /protein_start="92"
                     /score="45.7"
                     /tool="antismash"
                     /translation="SSSRVELLMLLARSGSPTMSELARTLDVTPRAVTRLVDGLEADGY
                     VVRERQADDARV"
ORIGIN
        1 tcaggccacg tcgcgttcga cggcgtcgag gctgtagtcg ccggcctcat cgatggcctc
       61 ggccagggcg gcgtcgtcca ggacgacgtc ggagaccacg gtggccaccg actggccgcc
      121 cttgctcagg acgacggaga cgttcttgac gccgtcaagg gccttgagct cctcggtgac
      181 gtgggcgacg cagtggtcgc aggtcaggcc cgagagcttg agggtggtgg tgcggtcggt
      241 gccgtcggcg gtgaactcgg acatggttgt gctccttggg ttgtgcgttc aggaccgcac
      301 gaggcgggcg atcgcgtcgg aggcctcgcg gatcttggcc tggccctcgg cgtcggaaga
      361 ctgggcggcg tgaatgacgc agtggctcat gtggtcctcg agcaggccga ggctgacggc
      421 ctggagggcc ttggtggccg cggcgacctg ggtgaggacg tcgatgcagt acgtgtcctg
      481 ctcgaccatg cgggagatgc cgcgaatctg gccctcaatg cggcgcagcc gcttgaggta
      541 gtcgtccttg gtgcccgtgt agccggccat ccgcgtctca cttcctcccc ggcttctgcc
      601 cgatacgtcg aggtgcccgt aacgataccc ttagggggta ggggtgtcaa tgaggtggcc
      661 gggcggcgtc gtgtgtcggt tcggcgaccg ggcgggggcc gggcggcggt gcgtgttgac
      721 tcggccgtgg ttgaggtcgg gacgtgcggc ccgagccggg gtcgggatcg gccgtatggc
      781 ccggattgag gccgaggcgt gcgacgcgac ggtccggcag ggccggttcc cgagcggttg
      841 cgcctggtgg tggcgggctt gcggccccag tggctcccgc gggcgcgatc gctgagggtc
      901 acgtccgaca acgggcctgc ggcttgttct gcgaggcgcg gttcggatgg tgtggcgcgg
      961 cacctgcaca tgggagagaa gggcttcgtc ggagtgggtg ctggctttcc gcatggtcct
     1021 gcggttcttc agttcccgtc aagacgagct gacgcgttcc catgtgcgca ttagggggtc
     1081 tgtgcacatg ggagtacgac aacctatctt gacggtgata tagaaacccc gagattccgg
     1141 ggaaaagtcg gtcctgcgtc attgaggccc cgctctccca tgtgcagctc tccgccccgc
     1201 cccggaatcg tcggccccga tcctgtgatg cgactgccag acgggcggcg cacagtcgaa
     1261 aatcttgtcc tgtggtcaat cgacggtacc gacgaggggt gtgatcgcgc cgtcatcggg
     1321 ccgacgcgcc ccccaaccct gaggcactcg gcgtcgccga ccttcgagct ggaccggtct
     1381 cggcgaaggc gacagcgggg gttgcgaggg gttgcgggcg ggcctgccgt ctgtcatcgg
     1441 cccggggtca ttcatgcggg tcggtgatca cgagggacgt cctgcctccg ggggtccctt
     1501 gcggtcatgg ggctctggtt tgaacgcggg ggctctgaca gcgggcaggg gacctgctgc
     1561 ccggcaccgg cttatcagag cctgtcgaga ccctggggct ccttgaggtg gccttctcct
     1621 agccgagaag cgaccgcctg cgcattttcg cggcgaccag cacggttgca ctcgccgaga
     1681 atctgcgcga cgtcgcggtt ctgtgatgcg ggcggagcgc agtgcggtgc tgagagcgcg
     1741 tgggagcgtc accttgcggg ggcgctggtg cctgttgggt gcttcgaacc gatctcggtg
     1801 cggaagtgag ccgatcttgg tgaagggggc gggtggggag gctcgggggt ggggggctgg
     1861 gcggggtggg cgtgagatcc tggtgctatg agcgtatcga ctgatcgcga ggatgttgac
     1921 acctgggctc ccgtcgggtg ggtgcctggt gacccgggct tcgacgaggc gcctttcggg
     1981 tctgtgctcg gtgaccctct tatgggttcg ccgttgttcg atgtcgcggt gctcgatgat
     2041 ccctttgagc atcggctgga ggaccggaag actgtgcgtg ggggccgggc ggcatcggcc
     2101 gagggcgccc agtccgatcc ggctgcggtg ctgcgtgctc gggtcgagga gcgggtgcgg
     2161 gccatgcggc gcggagtccc gcagagtcag caggcggctc cgcggtcttc ggggtacggg
     2221 cgcgcccctg gggcagggct gggcgctgct gcgagcgggc agcgccctcg gggcgcgcgg
     2281 cagcctgtgc ggcctgcgcg catgtccgcg ccggtgcccg cgccggtgcc gcagtcgtcc
     2341 tacggccgac ggccggggcc gcccggcggg tacggcggcg gatacggcgg ccgccctggt
     2401 caaccgatgg gctacggcgg cgggcccgga ggcccgatgg gctacggcgg cgggcccgga
     2461 ggcccgatgg gctacggcgg cgcaccggga gcgcctggac agccggccgg gtccggcctg
     2521 ccggcaccca tggccgttaa cccgtacgcg ccccctgggg tcgacggccg ccccggccgg
     2581 gctcgtcccc ctcagtctgt cggacgcggc cggaacaagg gggtcggccc ctacgtcggg
     2641 tggatcatct tcttcctgtt cctcgttatc tggcacatcg tcaggtgagt cccagtggcc
     2701 tcagggtcgg agaatgatgc tcttcggccc cggcactccg gtgaggagag cctgacaggg
     2761 gagccgaaga tggtggagac ccgttcggcg gggccgtggt cgcgcggcag ggcgctgctg
     2821 atgctgaagc ggattctgtg gtgggccggt ctggtgctgc tgctccccgg tccggcagcg
     2881 ctctataacg aagatgcgat ttacggcttc tttgcgtctc ttccgccgcg gctcgatacg
     2941 tcgacggggg atgtggatcg ttttctattg atgttgacgc tcacagagga gcgtattctg
     3001 gccacgcttg tcgcaggctt tgtgtgctgg gcgctctgcg ctgtcctcgg cttcgtcgtc
     3061 tttctgcgcg agtctgaccg tccggcgccg cggcgcagcg cgtggcgcgt tgtgaggcgg
     3121 ctgactattg tgatcgtatc gactgtcttc cttctggccg gcgccttggt cggactgctg
     3181 tgcaacatcg ggatagatct gtactacaac ccgatcccct gacgacctgc ggcacgggac
     3241 ccggcttctt gctcgggtcc cgccccgcct cctcggcgtg aatgctatcg gtgcggcagt
     3301 gagaggaatg ctgcataggc gcgcgcgagc acctctgcct cctgctcgga ggggaggcgc
     3361 ttcgcgtgcg ctgcgtctaa gagttttttc agggtgcagc caatattttt gagtcccaag
     3421 gcgtcgatgc cgtcggcaac cttcttaaag gctgtcacga cattgtctgc gcgtgacccg
     3481 aagcgctcac ggtagaagcg cccgatacga tgggtctcgc tctgcttgaa cacgtcgcgc
     3541 atcgcattcg tcagtgcgtt gcttgaggga ttgtgtatca tatttcgggc gataagccag
     3601 gcgtccgcat cggcgagcac atcctcgtat ccgaagcctt ttccgtcgtg catgcctccg
     3661 agatgcttct caagccaggc ggcaaggtcg gagctgtcgg cctctcgctc atatgcaccc
     3721 cagatttgca gtaggtcgag cggccagcct cccaggtccc ccagcccgta ctctttgttg
     3781 tcctcctcga tgccccactc caagcagccc accgccgtgg ccgccatgtg cgcgatatcg
     3841 cgattcggaa tcagtccctt gatcgccggc tgcttcttgc agacgccatt gcatatctgt
     3901 cgtgctgact caagctctga gggactggga atctccgggg tgtaaaggcg ccaaagaccg
     3961 ccgtacttgt ctccccagta ctcgggcttc ctgagccact cgagaatgaa ttcgccgatg
     4021 aatcctcggc aggcccttat gggatgtgat gccttgccca ggctctccag gcactcgcgc
     4081 tccgtcttct tcgaccacgc aagcagagga tcctcctccg gtttcgcggg gtcggggtcc
     4141 ggataaggtg ttgccgatga tgaggacaga acgctgctgc aggccgcaac tcgacctgcg
     4201 tgggcgacgc agtcaagatc ccattttcct gcgtagccgc tgatctcggc gaactggtcg
     4261 tagttccagt cggcggggat cgggtagcct aggtttcccg agaacccgga tgacatgtct
     4321 gagacgaagc tcgatatggt gtacccgtgt ttcgcgatct tgctgcaggt attacgcgag
     4381 gcgtatactc ccaccccgta gccgccgccc aggttctcct tgatcactct gaagtacggc
     4441 tcgatgacct ggtcgatctg gtactcgtat acgtccatgt cgacggcgaa gtagatcacc
     4501 gtcggcggga ttcccagacg gtgcgcggcc gcctgggcct cgcgggcgtg gcgcgctcca
     4561 ttctcgaacg tgaagtcgga cagctggcga gagttctcct ggaagatcgg aaaatatttc
     4621 agtccacccc cggtgatgcg ctcgagctcg ccgggacgaa tcgccttgaa atagtccccg
     4681 ggctgtttcg acgcctgatc cggctcggtg agatagcgtc ccacgatctg gtacttactc
     4741 gtcttcaggt gcgcgaggag cccactggtg atctagaaac gggtgtcgca cgcgtcacag
     4801 gggcgatccg gatcgccttt tgacgtcatc aggctcatcc acgtggtcgg gtcgatctta
     4861 ccgttgcgag ggagggcgta gtctttctgg aactgatcga ggccggcgtc ggtcgccccg
     4921 tgccactcct gggtgatccg gacggggtat ccgttgcaga cgagcaggac tgaggcgagc
     4981 cacacccact tcgggtaggt gggggcgttc gcggcatcga tctccacgag cttggatcgg
     5041 gtgccgaggc cgaaattgcc cgtggccttg tccggactat agccctcgac tgcctgcagt
     5101 gttttaatga gtgccgtgtt catctcccgt ccgtacaggc cgtccgtcgg gatgatcccc
     5161 acgtatgcgc ggtattcccg gttgagcttc tgctgggtac tgcgaatgct cggaatgccg
     5221 ccgtaacgcg ctagcagcac gaactgatcc atagacagga gggctctcat aatatctacg
     5281 gtgacggtgg agtcgccgcc gatacccatg tccgccttga ggccgcggat cgcattaccc
     5341 gtaccggcat agaaatgagt ggtgatactg ctccctgtgg agtacccctt gcaccacaac
     5401 gctccttgga taatgccgta tacatttgag gtggtcttgt cccctgcttc tgctgctgga
     5461 ttccggacgg ccagcgagac tgaaagcgcg actgggtgcc agggccgaag ttgtccgccg
     5521 tcgcggtgat gcccagttct atctgaagcg cgcgggtcag ggcgtggatg gtgccccatc
     5581 cggtctcccc gtcctccttg atggtgttga atccggtttt attgcggtat gcgcgattca
     5641 gccactgctg agtctgcaga accatttggt cactcatggc gccttcctgg ccggacgctg
     5701 ttcacgaacg ggagtcacgc cctcactcgg agtaggggcg ggacgcttcc gaatccattg
     5761 tccaccggtc gccgccgtat cggaaagttc tcaaccgggg gcagctggcg gaggcgggtg
     5821 cttcccctgc ttcttggcga gtggtgtgcc ggtggggcgg atggcgcacc gggcgaaccc
     5881 gaggcggcgt tggagagctg atggaggctc ggcggtgggc gcccgccgag ctctctggac
     5941 cgatctcgaa ccggaagtga accgatctcg gcgcggaact ggaccgatcc cggtaagtgg
     6001 gcggcggggc ccgggcggac ctggaatcgg gccgacgccc ggacgcgcca cggctacggt
     6061 gatccgccgg acccgagccc cgccccggag ggccgacgcc caggcgcgcc cgcgcgccgc
     6121 acctacaggg tggggcggta gcggagatcg acgcgctgtc actggacgcc tgcgcgccgc
     6181 acctacgggg tgggggcccg gccggagggc gcgcacctga gggcgggggc gtagccgtgc
     6241 ctgaaggccc acacgacgat ctcgaggcgg gaccgcgttt tcgtcttggt gaacagcacg
     6301 gagacgtgcg acttgaccgt ggcctcggag atggacagct gcgaggcgat cctccggttg
     6361 gaggcaccct cgcacagcat gtggaggacg tcgcgctccc ggttggacag ggcgacgctg
     6421 ccgtcctcgg cgtgtgcgga ggccagcacg tagtcgatca ggcgcgcggt cgacatcggg
     6481 gcgacgacct tcgccccgga gtgcacggtg cggaccgcag agaggatctc ctcagcgggc
     6541 gtgctcttga gcaggaagcc gctggcgccc gcgctcaggc ccgtgatgag gctgtcgtcg
     6601 gtgtcgacgg tggtcagcag gatgacgccg gtgctggggg agacccgcag cacctcccgc
     6661 gctatctgcg cgccgtccat ggtctccatg tggatgtcgg tgatgaagac gtccacccgg
     6721 ttcgactcga ggaacttcag cagctggtct gcccgacggg tcgcgagcag gatccggatg
     6781 tcctccgcct gggcgaagta ggactccagg caggacagcg ccatcgcgtc gtcgtcgagg
     6841 agagcgacgc cgatgtgttc gggaccaagg gaagtcaggg gactcatacg tctcctcgtg
     6901 aggtaaccgg cacgagccgc ggtcgcaggc gtccgcggcg tctgggaggt aacgataata
     6961 ttacgattca gagcatctgg gcactacggc ttgacggtgt tgagcgggtg tggattgggt
     7021 ggtgccaccg ggtgtcgtgc ccggcctcga tcggcccgac gtcgtcgcag acgtgctcga
     7081 agcgctggtc ttataggtgc cacctcaagc ccgtggttga actcataggt tcgggtgtat
     7141 ccgacattct tcctcccggg gtgcgtcgaa ggaatgagcg gggccttcaa ccggacggtg
     7201 cgcgcccctc cgaaaagaga cgccacagta tcccgatgac cggtttgcac gtccgcgacg
     7261 ccggtgcaga ctcttcccaa caacagcgcg tccctgacga tgcgcttgcc ctgttctcat
     7321 ctcggaaggc cgatccgtgt accgatccgc gctcaaggag ccaatcgctc cttcgctggc
     7381 ccgtgcggcg tctcttgagt cgccggtcgg cctggtctcc cgcaccgcgg agctggccca
     7441 ggcccccggg gagccggcct tctcgatctg gaccggcttc ctcggcgacc tctccgcgcc
     7501 gctgcgctcg cagaccacct ggaaccaccg ggtcgagtcc ggcaacatcg acggcgccgg
     7561 cggcgccatc gacgccgacc tcgccaggca catcgcgatc gtggagtccc tggagcgcta
     7621 ctcctcgtgc tcgtgggagg ccgaggagct gatctgggac accccggccg gcctcggcga
     7681 cgccgccatc ggaccggagc gctggcccgc atgctcgccc acggagctgg ccgacccgca
     7741 gtgcgggctc atcccctccg accccaggat cccgctgcgc tgggtgcggg gctggtccct
     7801 gacccggggc cgcgaggtct tcgtgccggc cgtcctggtc tacctcaagt tcccggtgcg
     7861 cagcccgtcg gagcgcttca tcaacatggt ctccaccggc acgaccgccc actccgacct
     7921 gcgcgaggcc gtcctcggcg gcctgctgga ggtcgtcgag cgcgacgcca tcgccctgac
     7981 ctggctgcag aggctgcgcc tgcccgaggt cgtggtggac cccgccgacc tcgaccccga
     8041 ggtcgccgag taccaccggg tcggcacctc caccgagctg acggtccacc tgcgcgaagc
     8101 caccaccgac tacggcattc cgatcctcta cgccgtccag acctccgagg tcgacaccga
     8161 gctggcccag gtggtggcgg ccacctgcga cctcgacccg cagcgggccc tggccaagat
     8221 ctaccgcgag ctcgtctcgc tgcgcatcgc cctgcgcagc cacgcccgca gcccgcgagc
     8281 caaggaggtc accggccagg acatgacggt ggtcggcggc gccctggccg acgccgcccc
     8341 ctccatgcgc cacgtcttcg acttcctcct ggagggcccc cggcccgcgc gccggctggc
     8401 cgacgtcggc cgccccgagc tccgcagcac ccgcgggccg tccgccggat cggccgccga
     8461 cccgctggcc cgggtcgtct ccgcgctgga gcgggccggg tcggaggccg tcgtcgtcga
     8521 tatcaccacc gacgaggccc gccaggtcgg gatgcacgtg gtcaaggccc tcgtccccga
     8581 ggccgtgccc ctgtccttca gccaccacgc ccgctacctc gccacccccc gcctctacga
     8641 cgctccccgc gccatgggcc tgaccgccca cgacgaggcc ggcatcaacc ccgtccgcca
     8701 gcccttcgcc tgacccgcac ccgcaggaga cccacatgag caccagcacc gccagcaccg
     8761 ccgcgcagcg gccggtgacg gcctatctgc cgcaggggcg cttcgggcac gccgtcgtcg
     8821 agcgcctcgt cgggccgcag gacgccgtcc tgcccgtcga tcacggcctg gtctacgcct
     8881 cggtcccgta cgccgaccgg ctcgtcatgg tcgccgacgc cgaccggacc gccctgcgcg
     8941 aggccctgga cgaggtgtcc ttcacccgct ccgtgccctc cctgggcctg gagctgaccc
     9001 ccaccgagct gcgctgcggg cccctggtcg tgcccggccg cacggcctgc tacagctgct
     9061 gcgccaggcg ccgccggcag cacggctacc gcccgcttcc cgacgacgtc gagccgctgc
     9121 cccagggcta cgcccgccac cacgtggtca tcgccgccgg gctggtggcg ctcgccctga
     9181 gtactctggc cgccccggcg gccggggccg ggagcggcgg agccgacaac gacagtgagc
     9241 tcggcggcca ggtgtggacg gtcgacctcg tgtccggcct gacctctctg gcccggaccg
     9301 tggccactga ccgctgccgg acctgctccg ggcgctacgc ggcccggcgc gacggcgtgc
     9361 ccgcgctcgc cgcgctcctg ccggagaggg tgatctgagt ggccaccgac accggtacgc
     9421 gcgccgccgg cgccgcggcc caggccgccg agccgagttc cgcggccccc gcggcccagg
     9481 ggatgagggc cgccgacgtg ggccgcgccg cccgccagga cctccagttc cgcatccccc
     9541 gcaggcccgt ggtccggcgc ggggtgcgca tgcgccgcga ggacgacacc tgggtgctcg
     9601 acggcgggcg caagagccag gtcctgggcg gggccttcgc ccgcgaccac ctgggcgccc
     9661 tgctggaggc ctgcgacggc agccgcacgc tcgaccagat cggcgagacc acgggcatcg
     9721 gcccgaacgg cgccttcgag gccgtctccc tgctgtggac cggcggcatc gtcgaggagg
     9781 gcgacaccga cccgcttccc gacccgcagc ccgccccgga gctggcctgc ctgctgtcgc
     9841 gcctgggcga ctccaccggc gtcaacgact cctggcagga cgccgcccgc cgcctgtcgg
     9901 ccgcccgggt ggcggtgatg ggcgacgccg acctggccgg cgagctcgtc ggggccctgg
     9961 accccacgct gggggcccgc gcggccggtg ccgaggaggg cgacaccctc gccgtcgtcg
    10021 tcgagactgc cggctccgga gcggcgcgcg gcgcggctga gcgctgctgg gccctcggcg
    10081 tccccctgct gcgggtgcgg gccgagcacg aggcggtgac ggtcggcccg tacatcgacc
    10141 cgagcttctc gccctgcctg gagtgcgcca ccgccggtga gcccggagcg gggacgacgc
    10201 cggggccgag ccgccgcgac cttgccgtcg gcctggcggc ccgggcggtg gccgcgctca
    10261 tcgcccgcgc caccaccacc cacctgccgg gcgactcccg ccgcatcgac ctggagacct
    10321 tcacccacac cgaccatccg gtgaccaccc gcccgggctg ccccgtctgc tcggtggcgg
    10381 gccggccggg ggcgccggac ggggcccgtg agctggacgg ggccgaggag ccgggcggtg
    10441 gccacgagtc gggcggctct gcaggggcgg ccgagccgcc ggtgccggtc gcgcccaccg
    10501 ccccggtcgg ggcccgctac gagcaggccg tggccatccc gccggccgcc ttcgtggact
    10561 ccaaggggca ccagcagcac tacaagccct ccaacctgcg ccttcagcgc gagttccgcg
    10621 actggcccac atgcccgcgc acgccgctgc cagacgccga cctggagcgc ctggagaggc
    10681 cgtggccggt cggggccggg cggggggcga gtgccgccat gccgggctcg aacgggtccg
    10741 acggcggcgc gggcgcaccg gccggcgccg cgggccgggg cggcgatccg ggcgcgtcag
    10801 cggagagcac ggccccgggc ctgtccaccg ggcggccgac gctcgccgag ctcgccaccg
    10861 tgctggccct ggcggtcggc gtgcgcgagc cgctgcgccc gcagccgcag ggcgcagacc
    10921 cctctgccga cgccccgaag ctgcgccggt ggacggcggc cggcggcaat atcggctcgg
    10981 tcaccgccta cgtcctcgtg cccggcggcg cccccgccgc tgccggcgtc ggctccgaca
    11041 ccgggcttgc cgccggagcc ggggcctccg ccgagaccgc cggagccggg cccgccgggg
    11101 ccaccgccgc tgccaggccc atcggctccg ccgacggcgc cgatactgcc gccggagccg
    11161 acccgtcggc gccgctcgcc ccgggcgtct acacatacat cgagcgcgac cacgccctgg
    11221 cccgggtggc gccgccgccc gaggcgcccg cggtgcccga cggcgcgggg gcgcggctcg
    11281 tcctgaccgg caacgtggac aagctctcca agaagtacat gtccttcggc ctgcggctcg
    11341 cggtccagga ctgcgggtgc tccctggagg tggtccggct cgtcgcccgc tgcctgggcc
    11401 tgcccctgcg ggcccgcgcc cgctgggacg agcgcgagct ggcctccgcc atcggcacag
    11461 acccgcgccg cgagccggtc gtcgccgtcg ttgacctggg ggccccggga gactcgcagg
    11521 tcccggcagg ctcgggagac tcgggaggtc gccgtgcgca ctgactacat gatcctgcgc
    11581 gagatcgtcg agggtttctc ggacccgcag gccgcgccga cctccgacgg cctggccgcg
    11641 cggcgcccgc gccggccgct ggcctgcgag ctcgccgacg tccccgaccc gcgggagggc
    11701 gggccccacc cgcacggttc ccccggctac ccgcacgacc tgcgccagac cttcgagcgg
    11761 cgctcctcga ccaccgacta cgcgcccgag cccctggacg ccgcgcctct cctggctgac
    11821 gtacgggccg ccctggtcga ggacgccgag gactggggcg aggacgccgg cgtcggctcc
    11881 ctggagccct tcgtcctgct gctgcggccc cgcggcgggc gcccgggcgt ctaccgggtg
    11941 cggcccgacg gcgtcgatct tctgggcgac ccgccgagcc cggaggagat cgagggcatg
    12001 accgtgcaga aggagttcgc ccgtgccggg gccatcgtct cggtggccgc cgacctcgac
    12061 caggccgacg cgtgggccgg cgcccacggc taccgccacg ccatgacgcg cgccgccgcc
    12121 gtcatctact cggtgcacct gcgcagcgcg gcccgcggcc tgaccggcac cgtcttcgcg
    12181 ggcctgtcgc cctcggccgt gcgccacctg ctcgactccg acggggtgag ccgccaccag
    12241 atgctcgccg tcaccatagc cgccccggcc gccccggccc gcgccgcgcc gtcgccctga
    12301 gccggacggc ggccccacag acgccccgcg ccgcggggtg aggggcccgg tccgtgcaga
    12361 ggaccggacc cctcgatgag gcccacgggc ctcgctcctg accagtgaca cgaaccagaa
    12421 aggaggtgaa cagcatatgg ctaacatcga cctcacactc accgacagcg acttcggtgt
    12481 ggaggagctc cccgagggca acgccctggg atgcgccttc tgcggtgcgt gcgcgtcgtg
    12541 cccgtcctgc gcggcctgct cgtcgtgccc gtcctgcgcg gcctgctcct cgtgcccgtc
    12601 ctgcgccgcg tgcgcctcga cgtcgtcctg ctgacgccgt cacgacggcg ggcggggggc
    12661 gccatgccct ccgcccgccg ccgcccacgc caccgcgaac cgacttgagg gagtcctgac
    12721 ccgatgacca tgacgacgag cccggcgagg acgccgggcg gcgacgtccc gcgcctgcgc
    12781 cgaggggtga cgctgatcgt cgggatggac gaccagccga tgctgttcga ctcgacgtcc
    12841 ggcgcctacc accgcctcgg gaaggccgcc gccttcatcg tcaaccagtt cgacgggtcg
    12901 cgctcgcttc ccaccattat cgaccagctc ccgcagcaga tcgacgacgc cggcaggcag
    12961 cgcatcaccc gcctcgtgga gtacctgcgc tccaagagcc tcctggaggg cggcgcccct
    13021 ccccgggtcg tgccgcagga gcgcgtccgc aagcgcgccg acggccgcca cgtcgcgccc
    13081 ccgcacgtcg gcaagcacga gcagatccac ccgccccgct ggagcggcaa ctggatgctg
    13141 ccgcggttca tgctgatccg cagctaccgc cgggcggtcg cccccgtggc ggcggcgctc
    13201 caccacctgc cggcgcgcac gctcggctgg ctgttcgtct tcgcagcggc gggcggctac
    13261 gccgcaggcg tggagagcct catccacctg tccggcggcc cccgtccggc cgtatccgtc
    13321 tacttcatcg cggtcgccat ccagctggtg agcattgtcg ggcacgagtc ctggcacgcg
    13381 atcgtggccg gctacctggg gacccccgtg cgcggcctgg gggtggcctt catgttctgg
    13441 gtgctgccga tcgcctacgt ggaccgtacc gactcctacc gggtgcgctc gaagctcggc
    13501 cgcgccatgc tcgccttcgc gggcatctgc tccgacggcg tcgtgtgcgg cgtcgaggcg
    13561 gcggtggccg cggcgtccac gggcaccgtg cggcaggtgg ccctgaccct gtgcgccttc
    13621 cagctcacca tgctcgtcac caacctcaac cccctcaccc agtccgacgg cgtggccacg
    13681 gtcgaggccc tgaccggctc ggtcaacctg cgcgggcgct ccatgctggt cctgcgctgc
    13741 gccctcacgc gcaccccgct gcccccggcg ctggcccgca tgcggctggc cgcgcgcggg
    13801 ggatacttcc tctacggcct ggcctgcgcg ctgctgagcg tggtcggcac cgtgttcggc
    13861 gtcatctggc tgggcttcat ggtggtgggc attgtgagag gagtgctcgc atgacacgca
    13921 tcgactccgg ggccggcgct caggcggcgg ccgggtgggc cgggcctccg acgccagtcg
    13981 gcctggccgg ttctgcggcg gtccgcagcg ccatatcggg ttcggcgggc tccgcgccgc
    14041 cctcgtccgg ccccgcggct gcccgtgcga ccgggcaggc tccgcccggc cccgcggcgg
    14101 ccccggccgc gtccgggcgc tcgcccgccc cggcgggacc cgcggctacg gccggcccgc
    14161 ccggcccggc gacggcagcg caggacggac ccgccgcggc tccggcgtcg gccggcccca
    14221 cggcggcgcc ggccgccctg ctccccgcgc tcgcgcgcct gggcggcctg ccggagtcgg
    14281 cggttcccgc acccgaggac gccctcatcg gggccctgga ccggctgcgc cgccttgaga
    14341 aggacatggc gcaggccggc gaccggctgc tcgaccccct gtaccgactc atccccgacc
    14401 tggagcgcga tgagcggcgg gcggtcctgc acgccaagcg cagggtgttc caggggcgcg
    14461 tcagcggcct gacgccgcgg gtgcggggga gcctgcccgc cgacgtcggc gccatgctct
    14521 ccgcctggga cgacctggtc gcccagcggc acgcggagca cgcgcgcctg gaggcggcgg
    14581 tgaccgcgga cctggaccgc agccgtgctg tgctggcggc cgggctcgac gacgccgact
    14641 acctgcgcgc cgtggcgatc gccgccccag cgctggtggc ggcgctgacc aggcgcgggc
    14701 gcaggctcga cgactcccgc gtgctgcgga ccctctactc cctggcgacc cgcacggccc
    14761 tgaaggccag ccccttcgcc ggcctgacca ccgtcagcga ggccggcagg cctgctcgcg
    14821 gacgccgccg ctgcacggtg gcgctccacc tggcccacgg gatcctctcc acgacggcgc
    14881 gcgacctcga tcccgacggc ctcctgcgtc tggaggccgc ccccgtcagg gacgtcgtcg
    14941 gccccgacga gggggaaggg gagccgacgc tcgccgtcgt cgccgagcac gactacgccg
    15001 acggcctggt cttccggcgc gaggaggttc agccggcccg gtggctcgcc gtcgcccatg
    15061 accggctgac cggcgggcgg tccgacgcgg cgccggtgag cgtgagtgag gccgccgggc
    15121 tcgtgggcgg gcgggcgccg cacctgcgcc tgcgccgcct gctcgcctcc ggggccgtgc
    15181 gcccccacgc tccgtggccg cgcggcgagg accccttccc cgccctgacg gccacgctgt
    15241 cggacgcgca gcggcgcgcc tggggcgagg accttgaaag gctgcagcgg ctcgggagga
    15301 tcgtcgcggt cgaggacggg ccggggcggg cggagctgct caccgacgtc cagcggctgg
    15361 cgcggcgcat cttccccgac ggcgagctgg ggggaaggcc gagcggcctg ctctacgagg
    15421 actgcgagtc gcgggggcag tgggctgacc cgatggaggt agcgggcctg cgccacgaca
    15481 tcgagaccct ggccggtctc gtggacccgt gggtgacccg ctcccacatc tacgacctca
    15541 tggtgcgccg gtacgtcgcc cgctacgggc gcggcggggt gtgcgaggac ccgctcgcct
    15601 tcgtcatggc cctggcgcac gcccccgacg gcgactcgga gatgctgggc gcggctgcgc
    15661 aggacatgag cgcagggccg gaccccgagc gcgcggccat gcccggcggc gtctcggcct
    15721 cgccgcggca catgggcgcc taccttcagc cggtcggcgg cccggaggcg ctcgggaccg
    15781 ggccgggggc cccgggggcg agcgtggccc ttggagcgcc gggcgcatcc tccagggcgc
    15841 cgggcgcagg gccgggggcg ccgcgggcct cccagggcct gacggtggtc aacgccttca
    15901 ccaacggcaa cggcgccctt caggcccgct tccaccggct gctgggacgc ggctaccgcg
    15961 cgcgtctggc gcaggggatc cgcgccgcct ggggagtcga gcgggtgctg gagatccagg
    16021 cggccaccga ctgcaacacc gctcaggccg cctcctgtgg cgtcctgacc ccgctcggcc
    16081 tgcccggcga gcccgcggcg ccggacgccg tcgccctgag ctcgctgcgg ctcgcccacg
    16141 acccgcgcac cgacacgctg ttcctggccg acgcccatgg gccggtgggg ctggcctacc
    16201 tcgggctcat tccgcagtac cggctcggcg ggtacctgtc ctggctggtc ctgctgagcg
    16261 acccgtgggc gcgcctggcg cccctggcgg accactggaa cagtcgtcgt cttgagatga
    16321 ccggcccgct gcccgatgcg gcggttcacg ccccgcgcgt cacccacggg cgtctggtca
    16381 cccgccggga gtcctggacc ttcccggccg gtcaggtgac cgggctgctg gaccgcgacc
    16441 tggcggcgac cctgctgagg gtggcggacc tgcgcgagca gtggggcatc ccggcggagg
    16501 tctacgtcca ccagcacctg ggcgcccggg ccgagcccgg cgccaccgcc gacgagcaca
    16561 agcctcggta cgtggacctg cgctcgccgg tgtccctgct ggcgctgcgc ggctggatcg
    16621 actcggccgc cgagcacctg agcctggtcg aggcgctgcc ggccagggac gagctggcgg
    16681 gtactacgcc tgccggtgag ccgaccgtac tggagtacct ggttggcgtg cagtggccca
    16741 agagcgaggg ggacgtgcgg tgacggcggt gcgggagcgg gacgacgtcg gcgggggacc
    16801 gactgccggg ggtgtggcgg gcggttcgga gaccacggcg gccgcggttg gcccgggtgc
    16861 ggggcttgcc ggggccggga gcgggagcgg cctgggcgca gggcaggccg gggcttcgac
    16921 aggcccgggc ccggccgagg accacccggc cgccgcggtt ggcccaggag cagccgagga
    16981 ccggcaggtc gactggttgt acgcgcgcat ctactgcggc ggcggggacg acacggatgc
    17041 gctgctgccc gggattgcgc ggtgggtcga tgaggcccgc gccgactggc cgatcctctc
    17101 catgcacttc ctgcgcttca tcgacctgcg cggtcaccac gtgcggctgc ggctgcaggc
    17161 cgacccggat gcgctggatg agctcttcga gcgcctcgac gtcctggacg ccaccgcacg
    17221 gcgggcgcgg gtgcgcgtgc tcgagcgcct cgtccccgac ccgatgaccg ccgccggcgg
    17281 caccgacggg cgggccggcg tggcgtgctc ggtgtacggg cccgagtacg acaagtacgg
    17341 cggcccggcg ggagtggagg aggccgagcg gcacttcgac gtctccagcc gctggtgcct
    17401 ggacaaccgg gtgtggacgg cgccccgccc gctgcccagg gtcgccctgg cggcccgctt
    17461 cctggcgcac gcggccgccg tcggggtgct gccgccggcc gagctgctgg gcgcccacct
    17521 gcgcacgtgg gggtcgcggc tccccgagcg tctgcgcgac ggcgccgcgc tcggcgctgt
    17581 ggtgcggcag gtgctcgggt gccgcctgga ggaggtgccg ggatgggcgc gtgccgacga
    17641 gctgaccggg cggctggccg acgacgccgg tcgcaccgtg cgccggatcg gtgcgggccc
    17701 cggcgggcgc cgggcgctgg acgtgctgca catggacgcc aaccgcttcg gcgtcaaccc
    17761 cgctgaggag tgcgtcgccg gggtgtgcgc ccgctacctg ctgggtgcgg gctgaaggcg
    17821 cgtcggggtg tgccggcctt gtgctgttcc cgctcccgcg ctgctcctgc tcccgctccc
    17881 cggcgtcgag atagacattt tcgtatgagg tagacggtgt caccgtctac ctcatacgaa
    17941 aatgtctatc tcgacgcagg tggggcgccg cgcgtcagtc gtccaggtgc gcgaccagct
    18001 gctcggccag ccccgtgtag gccgcggggg tcagggccag cagccggccc tcgacgtcgt
    18061 cgggcatgcc caggccggag atgaactcgc gcatggcctc cggcgtgatc cgccgcccgc
    18121 gcgtgagctc cctgagccgc tcgtaggggt cggccatgcc tctcgccccg gccacggcgg
    18181 ctgcccgcat ggcctgctgc accggctcgc ccaggacctc ccaggcggtg tcgaggtcct
    18241 cggccaggcg cgcccggtcg acgttgagcc ctgccaggcc gcggcggatg ttgtcgatgg
    18301 ccagcagcga gtgccccagg gccaccccga tattgcgctg cgtggtggag tcggtcaggt
    18361 cccgctggag gcgcgaggtc accagggtgg ccgccagcgt gtccagcagg gcgcaggaga
    18421 tctccaggtt cgcctccccg ttctcgaagc ggatcgggtt gaccttgtgc ggcatggtcg
    18481 atgagccggt ggagccctgg gcgctcaggc gctggcggaa gtagcccagg gagatgtagg
    18541 tccaggcgtc ggtggccagg ttgtgggcga tgcggttgaa gcgggcgatg tcggagtaga
    18601 gctcggcctg ccagtcgtgg gactcgatct gggtggtcag cgggttccag gtcagcccca
    18661 gggactccac gaagccgcgg gccaccgact cccagtcggc gccgggcacg gccacgacgt
    18721 gcgcgccgta ggtgccggtc gccccgttga tcttgcccag gtactcggcg ccctccacgc
    18781 ggcgcacctg gcggcgcagg cggtgggcga ggacggcgag ctccttgccg agcgtggtgg
    18841 gcgtggcgct ctggccgtgg gtgcgcgaga gcatcggggt gcccgcctgc ccgcgggcga
    18901 gtgcggccag gtcggccacg agcccgcggg cggccggcag ccagatctcc tgcacggcgg
    18961 cgcgcacggt cagggcgtag gcgaggttgt tgatgtcctc ggaggtgcag aagatgtgga
    19021 cgatctcgcc cacgcccggc aggacggtgg gggcgccgtc ggcggcccgg acgccggggg
    19081 cctgggcggc ggcgtccagg cggcgcttga gcaggtactc cacggctttg acgtcgtggc
    19141 gggtgacggc ctcgatctcg gccagctcgg cgatctcctc ggccccgaag ccctcgacga
    19201 cgccgcgcag gtaggccttc tcggagtcgc tcagcccggg cgcgccaggc aggacgccga
    19261 ggtcggtcag gtggatgagc cactcaacct cgacccgcag gcgggcccgg ttgagggcgg
    19321 cctcggacag gtggttgacg agcggggcgg ccaccgcgcg gtagcggccg tcaagggggc
    19381 ccagggcgat ggcgggggac acggcggaga ggtcgaccat gcgctcattg tggcaggccg
    19441 acggcggtgc ccgcggaggg gagggtctgt tggtggtatc cgcggcgggt tgggccggtg
    19501 cttgcgatgc gcgccctcgg ggcggcttgt ctacaatata atatatggtc caatatggcc
    19561 ggaattaaac aaaatggcat tctgaggcag ctgctgcggg attcctggtt ggtgtttgcg
    19621 gagaatctcg catgaggatt gcctcgtgca ggtcgacatg acggatgagg agcggggcat
    19681 cctcatcagg tggaggaagc gctcggacgc tctgcaagcc ggcggggact gagggcggag
    19741 gcaattctgt acactgcctg tggcgtcggc ctggtattac cgcggagatg gtcgagcggg
    19801 ccgaggagac ggtacgcgaa tggctgtcgc agtggcggca ggccaggctg agctccgtgg
    19861 taaccggtca cgccgtgggc gagaacgagg caaaactcaa gagagctcgc aagcaggtta
    19921 gtgacggcaa gacctgacgc agcagcagta agctctgtcc cgcctgcgca ttacgttctt
    19981 tcggcggcgg agcgcgggag gatgatcacg ccgtcgtcgt acgggttgtc gccgagaact
    20041 gcgtggatta caccgtcggg cttcgggccg tccttctccc ggatgtcctc aatgtcaagc
    20101 ttgttgtact cgagcatgga caggtagtac tccaggaagt ccttgtaccg gtccatgacc
    20161 tcacctcccc accatgcgac ggcgccttct gcgggggtac cggggcgccc gagaagggcc
    20221 acgtcgttct gggtctctga ggccgccacg gtgaagtagt cggcagctac gacaccatct
    20281 atagccatgg actccacgca ctcgggcaga tccaggggga ttcgcccggc atcgtacaac
    20341 ggtccaccca gaaggtcgtc ggtggagaag atcgtcatgt cctggtagaa gcacggccag
    20401 ccgttggagg ccagcaggaa accgcggtag gactccggca ggcggaagcc cagggtctcc
    20461 tcggtgcgcg ccacctcctc ctccgtggcc cgcacatgag gcagggcgta gtcccagatg
    20521 cccttccagt ccgctttcat gcgctcctgg gtcactttcc accccagtcc gatatagtca
    20581 ggccacgtca tccactgctc gccatcaaac ccggttacct tcgcatgcgg ttgaaacgac
    20641 ttgtatgtca ccagagccac cgattcctga tcccccaggt ctggtgattc cgtcagctga
    20701 cgacgacgga taaggcggta ggagcaactg cggtacgctg acgtctggtc ccgccacctt
    20761 ggcggaaaga acaaactcga cagcaaagaa ccgcaccagt caggctccta ccagtagatc
    20821 agttggccag cacctgcggg atcgcctcat ccaggtacca tgtccagaac gcccgacgag
    20881 ccggcacgtc ggtcttctca atcggcatcc agttcggggc gtgggctgcc gctcccgcgc
    20941 agcagtaact cggctcaagg gtgtctggaa gcagctcatc gtcatccgtt tcgtcgtctg
    21001 caatattgta atcaggattg cgatagcatg ctgaaatcac cgcatgtgag actccttcag
    21061 caacaagggt ggctgtcttt gcggcaaaat ctgcctctgt cgtcttgtcg agtacatgaa
    21121 caagaaaact ctctgcgtga atctgtgatt gctttggatc ggcctgctgg ttgatgagct
    21181 cctgtgccag ggtgagcatc tcctcgaccc tgctatcacc ggggaaggcc cggtcccaaa
    21241 gatgttgcac gtggcgcaca catgtcatct tcagctcgat ccggtgccgg tatgaggcct
    21301 cgtcgtcctg ggggtccagc atggcctccc agatccgcct gcgggttcct agggtcagga
    21361 tcgccttgtc actggcggcc agctcggccc ggccggcctc gatctcccgg ttcactgcgt
    21421 ccatgtcaat catgacaccc tcctcatccg ttgctctcca gcgccatccg atccgagcat
    21481 aatatcgatc ggttgcgtca tgatgttgtt caaggcttta ccactgtgcc gtcggggtag
    21541 aatatccatg tcccatccgg gtcggtgacg taccagcatc tcccctcgtg ctgggcgagc
    21601 ctgctgaagc agcccggaca gtcatcgcag agctccttcg ctacaccgat ggccggctcc
    21661 ttggccgtga tcgactcctg ccgctccgcg tgcgaggcat agtactgccc tggaacgccg
    21721 ttgtctctca taccggcgcg tttgacgggg tggccgatct cctcctgctt ggcgaggacc
    21781 tcatcgacat tgggcttctg gaaacccgtc ttgggacgcc tattctcgct ccagccactg
    21841 agagtctgac tatggtccga cgaagtcgcc ttatctttat agtctttgtt ttttccgata
    21901 tttgtctatg ggtgttttgt gcgcgttgct gggcttcctg ggagcgtctg gtcatctcgg
    21961 ggtcgggggt cttgtctccg ccggcggtcc cgtgtccggt gcctcctccg ccgtggcctg
    22021 tgcctccgtg tcctttgccg cctccggtgc ctttaccgcc gcgtctgcct cctgtgctgc
    22081 ctgtgccgct gttgtggccg gttgttcctg cgcctcggcc gccgcgcgcg ccgtgcgtgc
    22141 tcctgctggc acctcatttc gcgtggtgac agtgaaagaa ctggccgccc tggctagcca
    22201 ctcctggcta gccactatgg agggcgtgtc cttaccttcg atcgtccctt cgcctcccgg
    22261 tgcagagatg cggttatcct cccgctcagg ggcgggaact gttcagtgag agggtcgtac
    22321 cgctggtcac gatggctcat tgtggcaggc cgacggcggt gcccgcggaa gggagggtcg
    22381 gctggggccg ggcgcaccga aacgttgcag accgcagtcg acgtcgggtg cgcgagcctc
    22441 gggcacccgg gagaacgccg gggaatcggc gctccgcggg cgggcccgac gaggggcgcc
    22501 gcggcgaagg gcgcgacgcg cgccgacggg cccggcgagg ggaccggcgt cggcggacct
    22561 ccacggaaag cgcgccgagc ccgcgcgccg acgggccgct acctgtctcc gctgatgcgg
    22621 tcccacaggt cgcccaggtt ccttcgcagg ccgccggagt cgccgtcgcc ctggccgtcg
    22681 cccgcgtcgg cctcgcccgg gcccgggtcc tcggtcggcg cgccgccggg actctgctcg
    22741 gacgacagcg cggtcaccgc ggcggccgcg tcgacaatgc cggctccgca ggcgtcccgg
    22801 tcgcaggagg tcagcggctg ggacgcgtcc tgcaggaccg tggtggcctt cgccgtcgtg
    22861 aggccgggat ccacggactt gagcagcgcg accgtgccgg ccacgtgcgg ggcggcctgg
    22921 ctggtccccg ccatgaagac gtagggaggg gagtcggggg ccgactgctg gctcagggag
    22981 aggatgccgc tgtccacgtc ggggtcgccg ccgggggccg agacctcgac gccggtgccg
    23041 tagttggagt agaagctgcg ggcgccgttg ccgttggagg cgccgacggt gatgacgttc
    23101 tcgcagccgc ccgggctcac gccgctcacg tcctggtcct cgttcccggc ggaggcgacg
    23161 atgatcgacc cccggtccac ggcgtcgtcg atggccttct ggaggtaggc ggggcaggtg
    23221 ccggagccgc ccaggctcag gttgatgacc tgcgcggggt tcgcgttgtc cggagccccc
    23281 ttgacgctgc cgcccgacgc ccaggtcagg gcgtcaatga ggtccgtccc gccgccgcag
    23341 cggccgagca cgcgcacagg caggatcttg gcgtcggggg cgaccccggc cacgccggtg
    23401 ctgttgtcgg tcgaggcggc gatgatcccg gccacgtgcg agccgtgcca ggtggacttc
    23461 gtctccttgt tgccgttgcc gcaggcattg gcgacgacgc cgtcgcccat gtcggtgggg
    23521 tcgtcgtcgc ggccgtcgtc gtccccggcg atccaggagt cggagatgaa gtcgtagccg
    23581 ggcaggagct gcccgccgat gtccgggtgg tcgggaagga tgccggtgtc gaggacggcg
    23641 acggtcgctc ccctcccggt ggactgggac caggcgctcg tcgcgttgac gccgtgccgc
    23701 tcggcggtca gcccccactg gtagccgaag tactcgtcgt tgggcgtgcc cgcgctggtg
    23761 tcgagcgccg tcacccgcag ctcgggctcg gcggtctcga cggagtcgga ggaggtgagg
    23821 gcgtcgatga aggtccgtga cttctcaggg gtgagcgcct cgctcagctt cacggtggtc
    23881 aagcccccca cgtgggcagt ggcctgctcg acgacgacgg atgcctgctc tgcggcggcc
    23941 ctgagcgcgt cctggtcctt ctggggcaga gagccgataa tgtcgacgcc gtaggcatcg
    24001 acggagtcga tgaggctggc ggcctcggag cccttggccc aggtgatgac gaagcggtcg
    24061 gaggaggcgg cggcagcagt ggcggcgggg ctcgcggggg cgggcgcctc cccggacccg
    24121 ctcgtcgagg atccgctgga ggagcaggcg ctgacgacgc aggtgagggc gagggagaat
    24181 gcgcagagga gcgccaggag tgctgggcgc cttcgggaga cagtcctcat tgggcggtcc
    24241 ttgggtcggt gagggccccg gtgagggacc tgctccggtt gcggagcacc ctgagtctgg
    24301 cacaggagcg gagggattca gatgggcagc agtccccgcc ggggcgcgct gcccggcccc
    24361 ggtgcccctc gtggtccgcg gcgaaggtgc agatggtgta cagacgctca ttgacggcgg
    24421 actcgccgtc gcgcgtgccg agctgctcca cgctcggccc ccacaggccg cccgcgcccc
    24481 tggcggcccg gctcaggcca tcgggtccca gctgggaagg atgatcggcc cggcgtccag
    24541 cgccgcgcgg acctcgggcg gcaggcgccg ggcgcgcacg accacctggt agacgtactc
    24601 gtcgaaccag gagtcgttca tggtgtggaa gcccttctcg ccgaccttgt cgccccagga
    24661 gttctccacc cgccagcgcc gcggcgcgcc gtccaccagg tccacgcccg tcaggcacat
    24721 ggcgtgggtg agcgccgact cgcgcgccac cagccgctcc gccttcgtca tggacagctt
    24781 cacgccgtac aggccctcgt agtcgtgcag ggctgcgtcc cagacgcccg actccttgtc
    24841 ccgctgcttg gcgacgtcgc aggcgaacca caccggctcc ccgtcctgga tggcggcgac
    24901 cgccgccgcc ttgaggacgc ccagctcggc ggtgacgtgc tcctgggtgg gttcgcccac
    24961 catgaggtcg gtgcggtcga tgccgaaccg ggtgttgaga gggatctcgg ggcgcgggtc
    25021 gtgggccacg acgacgaact cctccagccc ggagacgtag cgccgggcga actcgaccgg
    25081 ggtgagagcg ccgacccggt ggaagacctt gcccctgtcc cggtactgcc acacgaactc
    25141 ggccggcggg gcgcccaggt ggatgaccag gacccggtgg acgtccgcca gcgccgccgc
    25201 ccggatcggc tcgagctcct ccccggcggc cgccgccgca cgcaggcgca ggacggtgcg
    25261 gcgcagcagc gtggcgaggt gatcgttcat ggcctccgag ctcgtcgccg agtccgcatc
    25321 cggcatggcg tagtggggga ccatcccgta cttggccacg agccgggcga actccggcca
    25381 ccagccgccg tcgccgatcg ggtcgcgcag ggaatcagcc acctcccggt cgtcgagcgg
    25441 gcgctcggcg tcgcccacgg cgcgggccag gaacgccgcc gccttctcca gcttgtcgta
    25501 gaagtagacg aagctctggc tcagctccac cgactccagg ttcagctctc tcatcagggc
    25561 ggcccgcagc acgttgaggc cggcgaaggc ccagcagcgc ccggagtgct tctggtcggt
    25621 gacggcggcg tcggggatga ggtcggagac cgaggtgtcg atcgaggtga ggatcgcgcg
    25681 gtccagggtg agtctttcga cgtcggtggt ggcgacggcg ttgccggcga cccgggcggc
    25741 gggatcggcg aggagggcgg cgttgcgggc ggcgacccag gaggggtcga cggcgtgggg
    25801 gttggtcatg gcgcgagggt agcgccgtcg tccttcattg ccggccccat ggcccggccc
    25861 tggatccggc cccatggccc ggccctggat ccagtacgcc tgcgcctgca ccgccttgcg
    25921 ggacaggccg gagccgatga ggtggcggcg cctgccgggg cgcacggcgc cctcccgcgc
    25981 ggcctcgacc ggggacggcg cacgaccccg atcgtcgccc gccggagccg ggacgagccg
    26041 ggcggctcgg ggcccggtga tctaggctcg ggtccatggg gttgttcagt gactggaggg
    26101 ccttccaccg cgccatccgc gcgcacggcg ggggcctgcg catcctgaag gaggcggcga
    26161 gggatctggc ctccctgaaa gagccgatgg agggggtggc cctcccggag ggggcggtgg
    26221 aggtggtcgc cccggagggg gcggtgtcga ccgaggacgt ggaccgggac ttcgagaccg
    26281 agtgctgggg cgcgctcgat gccctcgccg aggcgggcgg cggcaccgtg gtcgccatgg
    26341 gcatgggcgg cgagcgcctg gctctcctcc tggagcacct tctccccgac taccgtgccg
    26401 gcctcgacgt cgtcgccgtc gaggagcggg ggcccgctgc ggcgtcggcc cgcgagcgcc
    26461 tggggcccct gggcgcgcgc gtcgaggagc gcgccgacgc gggctcccgg ctgccgctcg
    26521 ccgacggcgg cgcgcgcctg gtcatgaacc ggctcaaggc gctcagcgtt cccgacgtcg
    26581 tccgcgtcct ggcccccggc gggctcctga tcacccagca ggtcgacgac gccggggctc
    26641 ccgggacccc cgatatcccc gtggcctccg aggttcccgg aatccctggg acccgtggcc
    26701 ggctcgacgc ccgggcgtcc cgcccgagcg tgcgcctgag ggcgatgacg gcggctctga
    26761 gcgaagccgg gctgattgtg gagagcactt cgcagtggtc gagggccgtg gacgttgaca
    26821 gcgcggacga gctcgccgcc gactggggcg cggtccaccc cggcgccccc gggcccgacc
    26881 gcgccgcggt gctggcgcgc atccgcgagg agtcgggcgg cggcccggtg ctgctggtgg
    26941 cccgccgctt ctgcatccgg gcccgccggc cgtcctgacc gcgaggcggg cggcctcggg
    27001 ccgtgtgggg cgggcggagc cattgggccc ggatgcccgg gaccgcccgg atggtgccgg
    27061 cgcgggcggg gccgtctcag gtcaggccga gctcggtgcg ggcccgggcg gagatgcgct
    27121 ggaggacccg gacggcggtg cgcaggtcgt cgccgtcgac gccctcgcac agggcgagca
    27181 gctgggacag gtgcgcctgg gcggcgcgcg cgacgcggtc gaggacctcg ggggtgcagc
    27241 gcacgcggat gacgcgggcg tcgtcggcct gccgctcgcg cacgacgtag ccgtcggcct
    27301 ccagcccgtc gacgagacgg gtgacggcgc gcggcgtgac gtcgagggtg cgggcgagct
    27361 cgctcatggt cgggctgccg gagcgggcga ggagcatgag cagctcgacc cgcgaggagg
    27421 acatgcccca ctccctctcg gcgtagcggt cgcgcaggcg ccgcagcagg ccgccgaggg
    27481 cgccgaccgt cgtcgtcgcg acgatgcccg cgacccggtc ggacatggag tccgcgtcgg
    27541 tccagggggc gccggcgacg acctccgcca gcagggggct gagctcgacg gcgcggtcag
    27601 cgccctcggg gaggcggggc gcctccaggg gccagccctc gtactccttt ggcggggtgc
    27661 ggggggcttc gtgcggggtc cgggcggtgg tggtcat
//
