GCF_003435335.1_ASM343533v1_genomic - 7 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

NZ_QVMD01000012 (original name was: NZ_QVMD01000012.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 4.1	cyclic-lactone-autoinducer	35,188	48,078

NZ_QVMD01000002 (original name was: NZ_QVMD01000002.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 12.1	lanthipeptide-class-ii	253,028	276,057
Region 12.2	ranthipeptide	284,550	305,995

NZ_QVMD01000004 (original name was: NZ_QVMD01000004.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 19.1	NRPS-like,cyclic-lactone-autoinducer	245,354	287,075
Region 19.2	ranthipeptide	340,077	361,728

NZ_QVMD01000005 (original name was: NZ_QVMD01000005.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 20.1	NRPS	67,407	120,709

NZ_QVMD01000007 (original name was: NZ_QVMD01000007.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 22.1	nucleoside	129,999	151,003

Region	Type	From	To	Similarity
Region 4.1	cyclic-lactone-autoinducer	35,188	48,078
Region 12.1	lanthipeptide-class-ii	253,028	276,057
Region 12.2	ranthipeptide	284,550	305,995
Region 19.1	NRPS-like,cyclic-lactone-autoinducer	245,354	287,075
Region 19.2	ranthipeptide	340,077	361,728
Region 20.1	NRPS	67,407	120,709
Region 22.1	nucleoside	129,999	151,003

No secondary metabolite regions were found in these records:: NZ_QVMD01000001 (original name was: NZ_QVMD01000001.1); NZ_QVMD01000010 (original name was: NZ_QVMD01000010.1); NZ_QVMD01000011 (original name was: NZ_QVMD01000011.1); NZ_QVMD01000013 (original name was: NZ_QVMD01000013.1); NZ_QVMD01000014 (original name was: NZ_QVMD01000014.1); NZ_QVMD01000015 (original name was: NZ_QVMD01000015.1); NZ_QVMD01000016 (original name was: NZ_QVMD01000016.1); NZ_QVMD01000017 (original name was: NZ_QVMD01000017.1); NZ_QVMD01000018 (original name was: NZ_QVMD01000018.1); NZ_QVMD01000019 (original name was: NZ_QVMD01000019.1); NZ_QVMD01000020 (original name was: NZ_QVMD01000020.1); NZ_QVMD01000021 (original name was: NZ_QVMD01000021.1); NZ_QVMD01000022 (original name was: NZ_QVMD01000022.1); NZ_QVMD01000023 (original name was: NZ_QVMD01000023.1); NZ_QVMD01000024 (original name was: NZ_QVMD01000024.1); NZ_QVMD01000003 (original name was: NZ_QVMD01000003.1); NZ_QVMD01000006 (original name was: NZ_QVMD01000006.1); NZ_QVMD01000008 (original name was: NZ_QVMD01000008.1); NZ_QVMD01000009 (original name was: NZ_QVMD01000009.1)

Compact view

c00004_NZ_QVMD.. - Region 1 - cyclic-lactone-autoinducer

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Location: 35,188 - 48,078 nt. (total: 12,891 nt) Show pHMM detection rules used

Region on contig edge.

cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

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core biosynthetic genes

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002009.1	0.16	Polyketide	kanglemycin A, kanglemycin V1, kanglemycin V2	Amycolatopsis vancoresmycina
BGC0000772.1	0.16	Saccharide	lipopolysaccharide	Brucella melitensis
BGC0001610.1	0.16	Other	gougerotin	Streptomyces ahygroscopicus subsp. wuzhouensis
BGC0000898.1	0.15	Saccharide	desosamine	Streptomyces venezuelae
BGC0000760.1	0.15	Saccharide	emulsan	Acinetobacter venetianus RAG-1 = CIP 110063
BGC0000899.1	0.15	Other	desosamine	Streptomyces narbonensis
BGC0000775.1	0.15	Saccharide	lipopolysaccharide	Legionella pneumophila
BGC0000790.1	0.15	Saccharide	O-antigen	Escherichia coli
BGC0001747.1	0.15	Other	pseudaminic acid	Tannerella forsythia
BGC0001774.1	0.15	Other	spicamycin	Streptomyces fimbriatus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002009.1	0.47	Polyketide	kanglemycin A, kanglemycin V1, kanglemycin V2	Amycolatopsis vancoresmycina
BGC0000772.1	0.46	Saccharide	lipopolysaccharide	Brucella melitensis
BGC0001610.1	0.46	Other	gougerotin	Streptomyces ahygroscopicus subsp. wuzhouensis
BGC0000898.1	0.46	Saccharide	desosamine	Streptomyces venezuelae
BGC0000760.1	0.46	Saccharide	emulsan	Acinetobacter venetianus RAG-1 = CIP 110063
BGC0000899.1	0.45	Other	desosamine	Streptomyces narbonensis
BGC0000775.1	0.45	Saccharide	lipopolysaccharide	Legionella pneumophila
BGC0000790.1	0.45	Saccharide	O-antigen	Escherichia coli
BGC0001747.1	0.45	Other	pseudaminic acid	Tannerella forsythia
BGC0001774.1	0.44	Other	spicamycin	Streptomyces fimbriatus

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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c00012_NZ_QVMD.. - Region 1 - lanthipeptide-class-ii

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Location: 253,028 - 276,057 nt. (total: 23,030 nt) Show pHMM detection rules used

lanthipeptide-class-ii: cds(LANC_like and DUF4135)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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MIBiG comparison

KnownClusterBlast

Lanthipeptides

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000554.1	0.23	RiPP	SRO15-3108	Streptomyces filamentosus NRRL 15998
BGC0000500.1	0.18	RiPP	carnolysin A1, carnolysin A2	Carnobacterium maltaromaticum
BGC0000525.1	0.18	RiPP	lichenicidin VK21 A1, lichenicidin VK21 A2	Bacillus licheniformis
BGC0000504.1	0.18	RiPP	cytolysin ClyLl, cytolysin ClyLs	Plasmid pAD1
BGC0000548.1	0.16	RiPP	salivaricin A	Streptococcus salivarius
BGC0000496.1	0.16	RiPP	AmfS	Streptomyces griseus subsp. griseus NBRC 13350
BGC0000561.1	0.16	RiPP	thermophilin 1277	Streptococcus thermophilus
BGC0000498.1	0.16	RiPP	bovicin HJ50	Streptococcus equinus
BGC0001787.1	0.16	RiPP	suicin 3908	Streptococcus suis
BGC0000527.1	0.15	RiPP	mersacidin	Bacillus sp. HIL-Y85/54728

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000554.1	0.56	RiPP	SRO15-3108	Streptomyces filamentosus NRRL 15998
BGC0000500.1	0.50	RiPP	carnolysin A1, carnolysin A2	Carnobacterium maltaromaticum
BGC0000525.1	0.49	RiPP	lichenicidin VK21 A1, lichenicidin VK21 A2	Bacillus licheniformis
BGC0000504.1	0.49	RiPP	cytolysin ClyLl, cytolysin ClyLs	Plasmid pAD1
BGC0000548.1	0.47	RiPP	salivaricin A	Streptococcus salivarius
BGC0000496.1	0.47	RiPP	AmfS	Streptomyces griseus subsp. griseus NBRC 13350
BGC0000561.1	0.46	RiPP	thermophilin 1277	Streptococcus thermophilus
BGC0000498.1	0.46	RiPP	bovicin HJ50	Streptococcus equinus
BGC0001787.1	0.46	RiPP	suicin 3908	Streptococcus suis
BGC0000527.1	0.46	RiPP	mersacidin	Bacillus sp. HIL-Y85/54728

Similar known gene clusters

No matches found.

Lanthipeptide predictions

Lanthipeptide(s) for ctg12_242 - Putative Class II

ctg12_243 leader / core peptide: MKENKNLEFA - GDLMAEVQEAQKVCCPDKGIERGRDhbDhbDhbDhaDCALFLDhbIFCC

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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Lanthipeptides

Core peptide predictions

ctg12_243 - Class II: Cleavage pHMM score: -2.20; RODEO score: 0; Monoisotopic mass: 4161.0 Da; Molecular weight: 4163.8 Da; Number of bridges: 5

c00012_NZ_QVMD.. - Region 2 - ranthipeptide

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Location: 284,550 - 305,995 nt. (total: 21,446 nt) Show pHMM detection rules used

ranthipeptide: (TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085 or SPASM)) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716 or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or YcaO or TIGR03882)))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000600.1	0.19	RiPP	thurincin H	Bacillus thuringiensis
BGC0001551.1	0.16	RiPP	citrulassin E	Streptomyces glaucescens
BGC0000551.1	0.16	RiPP	SapB	Streptomyces coelicolor A3(2)
BGC0000616.1	0.16	RiPP	amylocyclicin	Bacillus velezensis FZB42
BGC0000554.1	0.15	RiPP	SRO15-3108	Streptomyces filamentosus NRRL 15998
BGC0000489.1	0.15	RiPP	enterocin AS-48	Enterococcus faecalis
BGC0000516.1	0.15	RiPP	geobacillin II	Geobacillus thermodenitrificans
BGC0001484.1	0.15	Other	2'-chloropentostatin, 2'-amino-2'-deoxyadenosine	Actinomadura sp. ATCC 39365
BGC0001374.1	0.15	Other	thienodolin	Streptomyces albogriseolus
BGC0000294.1	0.15	NRP	acinetobactin	Acinetobacter baumannii

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000600.1	0.51	RiPP	thurincin H	Bacillus thuringiensis
BGC0001551.1	0.47	RiPP	citrulassin E	Streptomyces glaucescens
BGC0000551.1	0.47	RiPP	SapB	Streptomyces coelicolor A3(2)
BGC0000616.1	0.46	RiPP	amylocyclicin	Bacillus velezensis FZB42
BGC0000554.1	0.46	RiPP	SRO15-3108	Streptomyces filamentosus NRRL 15998
BGC0000489.1	0.46	RiPP	enterocin AS-48	Enterococcus faecalis
BGC0000516.1	0.45	RiPP	geobacillin II	Geobacillus thermodenitrificans
BGC0001484.1	0.45	Other	2'-chloropentostatin, 2'-amino-2'-deoxyadenosine	Actinomadura sp. ATCC 39365
BGC0001374.1	0.45	Other	thienodolin	Streptomyces albogriseolus
BGC0000294.1	0.44	NRP	acinetobactin	Acinetobacter baumannii

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

c00019_NZ_QVMD.. - Region 1 - NRPS-like,cyclic-lactone-autoinducer

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Location: 245,354 - 287,075 nt. (total: 41,722 nt) Show pHMM detection rules used

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))
cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002002.1	0.50	NRP	1,6-phenazinedimethanol, fontizine A	Serratia fonticola
BGC0000328.1	0.47	NRP	coronatine	Pseudomonas savastanoi pv. glycinea
BGC0000488.1	0.47	RiPP	circularin A	Clostridium beijerinckii
BGC0000427.1	0.42	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0000375.1	0.41	NRP	indigoidine	Streptomyces chromofuscus
BGC0000287.1	0.41	NRP	L-2-amino-4-methoxy-trans-3-butenoic acid	Pseudomonas aeruginosa PAO1
BGC0001399.1	0.40	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0001627.1	0.37	NRP	isonitrile lipopeptides	Mycobacterium tuberculosis H37Rv
BGC0001479.1	0.36	NRP	anabaenopeptin NZ857, nostamide A	Nostoc punctiforme PCC 73102
BGC0000599.1	0.35	RiPP	thuricin CD α, thuricin CD β	Bacillus thuringiensis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002002.1	0.63	NRP	1,6-phenazinedimethanol, fontizine A	Serratia fonticola
BGC0000328.1	0.60	NRP	coronatine	Pseudomonas savastanoi pv. glycinea
BGC0000488.1	0.57	RiPP	circularin A	Clostridium beijerinckii
BGC0000287.1	0.56	NRP	L-2-amino-4-methoxy-trans-3-butenoic acid	Pseudomonas aeruginosa PAO1
BGC0000599.1	0.55	RiPP	thuricin CD α, thuricin CD β	Bacillus thuringiensis
BGC0001627.1	0.55	NRP	isonitrile lipopeptides	Mycobacterium tuberculosis H37Rv
BGC0000427.1	0.54	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0000375.1	0.53	NRP	indigoidine	Streptomyces chromofuscus
BGC0000942.1	0.52	Other	petrobactin	Bacillus anthracis str. Ames
BGC0001399.1	0.52	NRP	fellutamide B	Aspergillus nidulans FGSC A4

Similar known gene clusters

No matches found.

Module view

Legend

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 245353 - 287075:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (gly)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg19_245

Search NORINE for peptide: strict or relaxed

AMP-binding (8..379): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: sysHIaEtiK
Nearest Stachelhaus code:: aad
Stachelhaus code match:: 40% (weak)

ctg19_249

Search NORINE for peptide: strict or relaxed

AMP-binding (9..389): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGmVWK
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 90% (moderate)

c00019_NZ_QVMD.. - Region 2 - ranthipeptide

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Location: 340,077 - 361,728 nt. (total: 21,652 nt) Show pHMM detection rules used

ranthipeptide: (TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085 or SPASM)) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716 or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or YcaO or TIGR03882)))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001540.1	0.15	Other	CC-1065	Streptomyces zelensis
BGC0001607.1	0.15	Other	gilvusmycin	Streptomyces sp. NRRL B-1347
BGC0000466.1	0.14	NRP	yatakemycin	Streptomyces sp. TP-A2060
BGC0000842.1	0.14	Other (Non-NRP beta-lactam)	carbapenem MM4550	Streptomyces argenteolus
BGC0001591.1	0.10	Other	fatty acid enol ester	uncultured bacterium CSLC2
BGC0001688.1	0.10	Other	N-tetradecanoyl tyrosine	uncultured bacterium CSLC2
BGC0000613.1	0.10	RiPP	thiomuracin A	Nonomuraea sp. Bp3714-39
BGC0001155.1	0.08	RiPP	GE2270	Planobispora rosea
BGC0000604.1	0.08	RiPP	GE2270A	Nonomuraea sp. WU8817
BGC0001558.1	0.04	Polyketide	cosmomycin C	Streptomyces sp. CNT302

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001540.1	0.45	Other	CC-1065	Streptomyces zelensis
BGC0001607.1	0.45	Other	gilvusmycin	Streptomyces sp. NRRL B-1347
BGC0000466.1	0.44	NRP	yatakemycin	Streptomyces sp. TP-A2060
BGC0000842.1	0.43	Other (Non-NRP beta-lactam)	carbapenem MM4550	Streptomyces argenteolus
BGC0001591.1	0.36	Other	fatty acid enol ester	uncultured bacterium CSLC2
BGC0001688.1	0.36	Other	N-tetradecanoyl tyrosine	uncultured bacterium CSLC2
BGC0000613.1	0.35	RiPP	thiomuracin A	Nonomuraea sp. Bp3714-39
BGC0001155.1	0.32	RiPP	GE2270	Planobispora rosea
BGC0000604.1	0.31	RiPP	GE2270A	Nonomuraea sp. WU8817
BGC0001558.1	0.20	Polyketide	cosmomycin C	Streptomyces sp. CNT302

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

c00020_NZ_QVMD.. - Region 1 - NRPS

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Location: 67,407 - 120,709 nt. (total: 53,303 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001399.1	0.31	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0000373.1	0.28	NRP	holomycin	Streptomyces clavuligerus ATCC 27064
BGC0001343.1	0.24	Polyketide	aurachin A, aurachin D	Stigmatella aurantiaca Sg a15
BGC0000343.1	0.24	NRP	enterobactin	Pseudomonas sp. J465
BGC0001469.1	0.24	NRP	marthiapeptide A	Brevibacillus sp. Leaf182
BGC0001444.1	0.23	Other	caboxamycin	Streptomyces sp. NTK 937
BGC0001538.1	0.23	NRP, Polyketide	caboxamycin	Streptomyces sp. NTK 937
BGC0000410.1	0.23	NRP	pseudomonine	Pseudomonas fluorescens
BGC0001591.1	0.22	Other	fatty acid enol ester	uncultured bacterium CSLC2
BGC0001688.1	0.22	Other	N-tetradecanoyl tyrosine	uncultured bacterium CSLC2

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001399.1	0.64	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0000373.1	0.61	NRP	holomycin	Streptomyces clavuligerus ATCC 27064
BGC0001343.1	0.58	Polyketide	aurachin A, aurachin D	Stigmatella aurantiaca Sg a15
BGC0000343.1	0.58	NRP	enterobactin	Pseudomonas sp. J465
BGC0001469.1	0.57	NRP	marthiapeptide A	Brevibacillus sp. Leaf182
BGC0001444.1	0.56	Other	caboxamycin	Streptomyces sp. NTK 937
BGC0001538.1	0.56	NRP, Polyketide	caboxamycin	Streptomyces sp. NTK 937
BGC0000410.1	0.56	NRP	pseudomonine	Pseudomonas fluorescens
BGC0001591.1	0.55	Other	fatty acid enol ester	uncultured bacterium CSLC2
BGC0001688.1	0.55	Other	N-tetradecanoyl tyrosine	uncultured bacterium CSLC2

Similar known gene clusters

No matches found.

Module view

Legend

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 67406 - 120709:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (cys - cys) + (cys)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg20_83

Search NORINE for peptide: strict or relaxed

AMP-binding (24..424): X

NRPSPredictor2: dhb, sal

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: dhb, sal
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: PLPgiGqVmK
Nearest Stachelhaus code:: dhb
Stachelhaus code match:: 60% (weak)

ctg20_87

Search NORINE for peptide: strict or relaxed

AMP-binding (548..944): cys

NRPSPredictor2: cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DLYNLSmIWK
Nearest Stachelhaus code:: cys
Stachelhaus code match:: 90% (moderate)

AMP-binding (1969..2368): cys

NRPSPredictor2: cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DLYNLSLIWK
Nearest Stachelhaus code:: cys
Stachelhaus code match:: 100% (strong)

ctg20_88

Search NORINE for peptide: strict or relaxed

AMP-binding (528..920): cys

NRPSPredictor2: cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DLFNLSLIWK
Nearest Stachelhaus code:: cys
Stachelhaus code match:: 100% (strong)

c00022_NZ_QVMD.. - Region 1 - nucleoside

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Location: 129,999 - 151,003 nt. (total: 21,005 nt) Show pHMM detection rules used

nucleoside: (LipM or LipV or LipU or ToyB or TunD or pur6 or pur10 or nikJ or nikO or truD)

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001862.1	0.20	RiPP	geocillicin	Aeribacillus pallidus
BGC0001930.1	0.20	RiPP	pallidocin	Aeribacillus pallidus
BGC0000938.1	0.18	Other (Aminocoumarin)	fosfomycin	Streptomyces fradiae
BGC0000600.1	0.17	RiPP	thurincin H	Bacillus thuringiensis
BGC0001579.1	0.17	RiPP	duramycin	Streptomyces cinnamoneus
BGC0000554.1	0.16	RiPP	SRO15-3108	Streptomyces filamentosus NRRL 15998
BGC0001526.1	0.16	Other	bartolosides E, bartolosides F, bartolosides G, bartolosides H, bartolosides I, bartolosides J, bartolosides K	Synechocystis salina LEGE 06099
BGC0001120.1	0.16	NRP, Polyketide	burkholderic acid	Burkholderia thailandensis E264
BGC0001525.1	0.16	Other	bartoloside 2, bartoloside 3, bartoloside 4	Synechocystis salina LEGE 06155
BGC0000563.1	0.16	RiPP	venezuelin	Streptomyces venezuelae ATCC 10712

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001862.1	0.52	RiPP	geocillicin	Aeribacillus pallidus
BGC0001930.1	0.52	RiPP	pallidocin	Aeribacillus pallidus
BGC0000938.1	0.49	Other (Aminocoumarin)	fosfomycin	Streptomyces fradiae
BGC0000600.1	0.47	RiPP	thurincin H	Bacillus thuringiensis
BGC0001579.1	0.47	RiPP	duramycin	Streptomyces cinnamoneus
BGC0000554.1	0.47	RiPP	SRO15-3108	Streptomyces filamentosus NRRL 15998
BGC0001526.1	0.47	Other	bartolosides E, bartolosides F, bartolosides G, bartolosides H, bartolosides I, bartolosides J, bartolosides K	Synechocystis salina LEGE 06099
BGC0001120.1	0.47	NRP, Polyketide	burkholderic acid	Burkholderia thailandensis E264
BGC0001525.1	0.47	Other	bartoloside 2, bartoloside 3, bartoloside 4	Synechocystis salina LEGE 06155
BGC0000563.1	0.47	RiPP	venezuelin	Streptomyces venezuelae ATCC 10712

Similar known gene clusters

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Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

Selected features only

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