GCF_000375365.1_ASM37536v1_genomic - 5 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

NZ_AQXB01000001 (original name was: NZ_AQXB01000001.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1.1	terpene	458,489	479,340	carotenoid	Terpene	25%

NZ_AQXB01000002 (original name was: NZ_AQXB01000002.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 2.1	T1PKS	41,880	86,778
Region 2.2	NRPS	299,334	346,020	7-deoxypactamycin	Polyketide:Iterative type I + Saccharide:Hybrid/tailoring	7%

NZ_AQXB01000004 (original name was: NZ_AQXB01000004.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 4.1	RiPP-like	103,408	113,710

NZ_AQXB01000007 (original name was: NZ_AQXB01000007.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 7.1	NRPS	1	43,114

No secondary metabolite regions were found in these records:: NZ_AQXB01000003 (original name was: NZ_AQXB01000003.1); NZ_AQXB01000005 (original name was: NZ_AQXB01000005.1); NZ_AQXB01000006 (original name was: NZ_AQXB01000006.1); NZ_AQXB01000008 (original name was: NZ_AQXB01000008.1); NZ_AQXB01000009 (original name was: NZ_AQXB01000009.1); NZ_AQXB01000010 (original name was: NZ_AQXB01000010.1); NZ_AQXB01000011 (original name was: NZ_AQXB01000011.1); NZ_AQXB01000012 (original name was: NZ_AQXB01000012.1); NZ_AQXB01000013 (original name was: NZ_AQXB01000013.1); NZ_AQXB01000014 (original name was: NZ_AQXB01000014.1); NZ_AQXB01000015 (original name was: NZ_AQXB01000015.1); NZ_AQXB01000016 (original name was: NZ_AQXB01000016.1); NZ_AQXB01000017 (original name was: NZ_AQXB01000017.1); NZ_AQXB01000018 (original name was: NZ_AQXB01000018.1); NZ_AQXB01000019 (original name was: NZ_AQXB01000019.1); NZ_AQXB01000020 (original name was: NZ_AQXB01000020.1); NZ_AQXB01000021 (original name was: NZ_AQXB01000021.1); NZ_AQXB01000022 (original name was: NZ_AQXB01000022.1); NZ_AQXB01000023 (original name was: NZ_AQXB01000023.1); NZ_AQXB01000024 (original name was: NZ_AQXB01000024.1); NZ_AQXB01000025 (original name was: NZ_AQXB01000025.1); NZ_AQXB01000026 (original name was: NZ_AQXB01000026.1); NZ_AQXB01000027 (original name was: NZ_AQXB01000027.1); NZ_AQXB01000028 (original name was: NZ_AQXB01000028.1); NZ_AQXB01000029 (original name was: NZ_AQXB01000029.1); NZ_AQXB01000030 (original name was: NZ_AQXB01000030.1); NZ_AQXB01000031 (original name was: NZ_AQXB01000031.1); NZ_AQXB01000032 (original name was: NZ_AQXB01000032.1); NZ_AQXB01000033 (original name was: NZ_AQXB01000033.1); NZ_AQXB01000034 (original name was: NZ_AQXB01000034.1); NZ_AQXB01000035 (original name was: NZ_AQXB01000035.1); NZ_AQXB01000036 (original name was: NZ_AQXB01000036.1); NZ_AQXB01000037 (original name was: NZ_AQXB01000037.1); NZ_AQXB01000038 (original name was: NZ_AQXB01000038.1); NZ_AQXB01000039 (original name was: NZ_AQXB01000039.1)

Compact view

c00001_NZ_AQXB.. - Region 1 - terpene

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Location: 458,489 - 479,340 nt. (total: 20,852 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000650.1	0.34	Terpene	carotenoid	Algoriphagus sp. KK10202C
BGC0000648.1	0.29	Terpene	carotenoid	Myxococcus xanthus
BGC0000643.1	0.21	Terpene	carotenoid	Brevundimonas vesicularis
BGC0000634.1	0.21	Terpene	carotenoid	Brevundimonas sp. SD212
BGC0000640.1	0.20	Terpene	carotenoid	Enterobacteriaceae bacterium DC404
BGC0000630.1	0.20	Terpene	(2R,3S,3'S)-2-hydroxyastaxanthin	Paracoccus haeundaensis
BGC0000633.1	0.18	Terpene	carotenoid	Streptomyces avermitilis
BGC0000664.1	0.18	Terpene	isorenieratene	Streptomyces griseus subsp. griseus NBRC 13350
BGC0000646.1	0.17	Terpene	β-carotein	uncultured bacterium
BGC0000637.1	0.17	Terpene	carotenoid	Corynebacterium glutamicum

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000650.1	0.67	Terpene	carotenoid	Algoriphagus sp. KK10202C
BGC0000648.1	0.63	Terpene	carotenoid	Myxococcus xanthus
BGC0000643.1	0.54	Terpene	carotenoid	Brevundimonas vesicularis
BGC0000634.1	0.53	Terpene	carotenoid	Brevundimonas sp. SD212
BGC0000640.1	0.52	Terpene	carotenoid	Enterobacteriaceae bacterium DC404
BGC0000630.1	0.52	Terpene	(2R,3S,3'S)-2-hydroxyastaxanthin	Paracoccus haeundaensis
BGC0000633.1	0.50	Terpene	carotenoid	Streptomyces avermitilis
BGC0000664.1	0.49	Terpene	isorenieratene	Streptomyces griseus subsp. griseus NBRC 13350
BGC0000646.1	0.49	Terpene	β-carotein	uncultured bacterium
BGC0000637.1	0.48	Terpene	carotenoid	Corynebacterium glutamicum

Similar known gene clusters

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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c00002_NZ_AQXB.. - Region 1 - T1PKS

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Location: 41,880 - 86,778 nt. (total: 44,899 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001909.1	0.32	Polyketide	strobilurin	Strobilurus tenacellus
BGC0001831.1	0.24	Polyketide	alkylpyrone-407, alkylpyrone-393	Myxococcus xanthus DK 1622
BGC0001526.1	0.22	Other	bartolosides E, bartolosides F, bartolosides G, bartolosides H, bartolosides I, bartolosides J, bartolosides K	Synechocystis salina LEGE 06099
BGC0001897.1	0.22	Polyketide	cepacin A	Burkholderia ambifaria IOP40-10
BGC0001162.1	0.21	Polyketide	1-heptadecene	Moorea producens JHB
BGC0001163.1	0.21	Polyketide	1-heptadecene	Moorea producens 3L
BGC0001161.1	0.21	Polyketide	1-heptadecene	Moorea bouillonii PNG
BGC0001525.1	0.21	Other	bartoloside 2, bartoloside 3, bartoloside 4	Synechocystis salina LEGE 06155
BGC0001343.1	0.21	Polyketide	aurachin A, aurachin D	Stigmatella aurantiaca Sg a15
BGC0001927.1	0.20	Other	A-94964	Streptomyces sp.

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001909.1	0.65	Polyketide	strobilurin	Strobilurus tenacellus
BGC0001831.1	0.58	Polyketide	alkylpyrone-407, alkylpyrone-393	Myxococcus xanthus DK 1622
BGC0001526.1	0.55	Other	bartolosides E, bartolosides F, bartolosides G, bartolosides H, bartolosides I, bartolosides J, bartolosides K	Synechocystis salina LEGE 06099
BGC0001897.1	0.54	Polyketide	cepacin A	Burkholderia ambifaria IOP40-10
BGC0001162.1	0.54	Polyketide	1-heptadecene	Moorea producens JHB
BGC0001163.1	0.54	Polyketide	1-heptadecene	Moorea producens 3L
BGC0001161.1	0.54	Polyketide	1-heptadecene	Moorea bouillonii PNG
BGC0001525.1	0.53	Other	bartoloside 2, bartoloside 3, bartoloside 4	Synechocystis salina LEGE 06155
BGC0001343.1	0.53	Polyketide	aurachin A, aurachin D	Stigmatella aurantiaca Sg a15
BGC0001927.1	0.53	Other	A-94964	Streptomyces sp.

Similar known gene clusters

No matches found.

Module view

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Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 41879 - 86778:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg2_60

CAL_domain (64..533): pk

minowa: Acetyl-CoA

Prediction, score:

Acetyl-CoA: 24.0
AHBA: 10.2
NH2: 8.7
shikimic_acid: 0.0
fatty_acid: 0.0

ctg2_61

PKS_AT (645..949): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 62.5%

minowa: fatty_acid

Prediction, score:

fatty_acid: 90.3
Malonyl-CoA: 68.1
Methylmalonyl-CoA: 64.9
Methoxymalonyl-CoA: 64.1
Acetyl-CoA: 40.8
Propionyl-CoA: 37.0
Ethylmalonyl-CoA: 35.4
Isobutyryl-CoA: 29.8
trans-1,2-CPDA: 26.2
CHC-CoA: 23.9
2-Methylbutyryl-CoA: 23.5
inactive: 21.0
Benzoyl-CoA: 8.8
3-Methylbutyryl-CoA: 0.0

c00002_NZ_AQXB.. - Region 2 - NRPS

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Location: 299,334 - 346,020 nt. (total: 46,687 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000410.1	0.31	NRP	pseudomonine	Pseudomonas fluorescens
BGC0001399.1	0.26	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0000349.1	0.23	NRP	erythrochelin	Saccharopolyspora erythraea NRRL 2338
BGC0000343.1	0.22	NRP	enterobactin	Pseudomonas sp. J465
BGC0001833.1	0.22	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001758.1	0.22	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0000426.1	0.22	NRP	sevadicin	Paenibacillus larvae
BGC0001844.1	0.22	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0000375.1	0.22	NRP	indigoidine	Streptomyces chromofuscus
BGC0001131.1	0.22	NRP	ambactin	Xenorhabdus miraniensis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000410.1	0.64	NRP	pseudomonine	Pseudomonas fluorescens
BGC0001399.1	0.59	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0000349.1	0.56	NRP	erythrochelin	Saccharopolyspora erythraea NRRL 2338
BGC0000343.1	0.55	NRP	enterobactin	Pseudomonas sp. J465
BGC0001833.1	0.55	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001758.1	0.55	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0000426.1	0.55	NRP	sevadicin	Paenibacillus larvae
BGC0001844.1	0.55	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0000375.1	0.55	NRP	indigoidine	Streptomyces chromofuscus
BGC0001131.1	0.55	NRP	ambactin	Xenorhabdus miraniensis

Similar known gene clusters

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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c00004_NZ_AQXB.. - Region 1 - RiPP-like

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Location: 103,408 - 113,710 nt. (total: 10,303 nt) Show pHMM detection rules used

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000487.1	0.17	RiPP	carnocyclin	Carnobacterium maltaromaticum
BGC0000554.1	0.17	RiPP	SRO15-3108	Streptomyces filamentosus NRRL 15998
BGC0000563.1	0.16	RiPP	venezuelin	Streptomyces venezuelae ATCC 10712
BGC0001579.1	0.16	RiPP	duramycin	Streptomyces cinnamoneus
BGC0000551.1	0.16	RiPP	SapB	Streptomyces coelicolor A3(2)
BGC0000513.1	0.16	RiPP	Ery-9, Ery-6, Ery-8, Ery-7, Ery-5, Ery-4, Ery-3	Saccharopolyspora erythraea NRRL 2338
BGC0000759.1	0.16	Saccharide	diutan polysaccharide	Sphingomonas sp. ATCC 53159
BGC0000486.1	0.15	RiPP	butyrivibriocin AR10	Butyrivibrio fibrisolvens
BGC0000797.1	0.15	Saccharide	sphingan polysaccharide	Sphingomonas sp. S88
BGC0000768.1	0.15	Saccharide	gellan polysaccharide	Sphingomonas elodea ATCC 31461

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000487.1	0.48	RiPP	carnocyclin	Carnobacterium maltaromaticum
BGC0000554.1	0.48	RiPP	SRO15-3108	Streptomyces filamentosus NRRL 15998
BGC0000563.1	0.47	RiPP	venezuelin	Streptomyces venezuelae ATCC 10712
BGC0001579.1	0.47	RiPP	duramycin	Streptomyces cinnamoneus
BGC0000551.1	0.47	RiPP	SapB	Streptomyces coelicolor A3(2)
BGC0000513.1	0.46	RiPP	Ery-9, Ery-6, Ery-8, Ery-7, Ery-5, Ery-4, Ery-3	Saccharopolyspora erythraea NRRL 2338
BGC0000759.1	0.46	Saccharide	diutan polysaccharide	Sphingomonas sp. ATCC 53159
BGC0000486.1	0.46	RiPP	butyrivibriocin AR10	Butyrivibrio fibrisolvens
BGC0000797.1	0.46	Saccharide	sphingan polysaccharide	Sphingomonas sp. S88
BGC0000768.1	0.46	Saccharide	gellan polysaccharide	Sphingomonas elodea ATCC 31461

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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c00007_NZ_AQXB.. - Region 1 - NRPS

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Location: 1 - 43,114 nt. (total: 43,114 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001699.1	0.21	Polyketide	nidulanin A	Aspergillus nidulans FGSC A4
BGC0000410.1	0.21	NRP	pseudomonine	Pseudomonas fluorescens
BGC0001758.1	0.20	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0001075.1	0.19	Terpene, Polyketide	aurachin RE	Rhodococcus erythropolis
BGC0001636.1	0.19	NRP	KK-1	Curvularia clavata
BGC0000665.1	0.19	Terpene, Alkaloid	xiamycin	Streptomyces sp. HKI0576
BGC0000666.1	0.19	Terpene	xiamycin A	Streptomyces sp. SCSIO 02999
BGC0001140.1	0.18	Terpene	platensimycin, platencin	Streptomyces platensis
BGC0001156.1	0.18	Terpene	platencin	Streptomyces platensis
BGC0000513.1	0.18	RiPP	Ery-9, Ery-6, Ery-8, Ery-7, Ery-5, Ery-4, Ery-3	Saccharopolyspora erythraea NRRL 2338

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001699.1	0.54	Polyketide	nidulanin A	Aspergillus nidulans FGSC A4
BGC0000410.1	0.54	NRP	pseudomonine	Pseudomonas fluorescens
BGC0001758.1	0.53	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0001075.1	0.51	Terpene, Polyketide	aurachin RE	Rhodococcus erythropolis
BGC0001636.1	0.51	NRP	KK-1	Curvularia clavata
BGC0000665.1	0.51	Terpene, Alkaloid	xiamycin	Streptomyces sp. HKI0576
BGC0000666.1	0.51	Terpene	xiamycin A	Streptomyces sp. SCSIO 02999
BGC0001140.1	0.50	Terpene	platensimycin, platencin	Streptomyces platensis
BGC0001156.1	0.50	Terpene	platencin	Streptomyces platensis
BGC0000513.1	0.50	RiPP	Ery-9, Ery-6, Ery-8, Ery-7, Ery-5, Ery-4, Ery-3	Saccharopolyspora erythraea NRRL 2338

Similar known gene clusters

No matches found.

Module view

Legend

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 43114:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (cys - Me-cys)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg7_10

Search NORINE for peptide: strict or relaxed

AMP-binding (526..928): cys

NRPSPredictor2: cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DLFNLSmIWK
Nearest Stachelhaus code:: cys
Stachelhaus code match:: 90% (moderate)

AMP-binding (2911..3327): cys

NRPSPredictor2: cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DLFNLSLIWK
Nearest Stachelhaus code:: cys
Stachelhaus code match:: 100% (strong)