Select genomic region:
Overview
12.1
14.1
17.1
17.2
19.1

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_GG667198.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 12.1 | ectoine | 7,898 | 18,209 |

NZ_GG667196.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 14.1 | terpene | 35,398 | 56,249 | carotenoid | Terpene | 62%

NZ_GG667193.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 17.1 | T1PKS | 49,281 | 94,059 |
Region 17.2 | NAPAA | 185,502 | 219,278 |

NZ_GG667191.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 19.1 | lanthipeptide-class-i | 83,558 | 109,876 | geobacillin I | RiPP:Lanthipeptide | 20%

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 12.1 | ectoine | 7,898 | 18,209 |
Region 14.1 | terpene | 35,398 | 56,249 | carotenoid | Terpene | 62%
Region 17.1 | T1PKS | 49,281 | 94,059 |
Region 17.2 | NAPAA | 185,502 | 219,278 |
Region 19.1 | lanthipeptide-class-i | 83,558 | 109,876 | geobacillin I | RiPP:Lanthipeptide | 20%

No secondary metabolite regions were found in these records:
  NZ_GG667209.1
  NZ_GG667208.1
  NZ_GG667207.1
  NZ_GG667206.1
  NZ_GG667205.1
  NZ_GG667204.1
  NZ_GG667203.1
  NZ_GG667202.1
  NZ_GG667201.1
  NZ_GG667200.1
  NZ_GG667199.1
  NZ_GG667197.1
  NZ_GG667195.1
  NZ_GG667194.1
  NZ_GG667192.1

Compact view
NZ_GG667198.1 - Region 1 - ectoine
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 7,898 - 18,209 nt. (total: 10,312 nt) Show pHMM detection rules used
ectoine: ectoine_synt

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | ectoine | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000859.1 |  | 0.27 | Other | ectoine | Methylomicrobium alcaliphilum
BGC0000857.1 |  | 0.21 | Other | ectoine | Methylophaga alcalica
BGC0000854.1 |  | 0.21 | Other | ectoine | Methylomicrobium alcaliphilum 20Z
BGC0000913.1 |  | 0.15 | Other | MK-8 | Enterobacter cloacae
BGC0000903.1 |  | 0.14 | Other | fluorometabolite | Streptomyces cattleya
BGC0001778.1 |  | 0.13 | Other | showdomycin | Streptomyces showdoensis
BGC0000343.1 |  | 0.05 | NRP | enterobactin | Pseudomonas sp. J465
BGC0001073.1 |  | 0.04 | NRP, Polyketide | kosinostatin | Micromonospora sp. TP-A0468
BGC0001852.1 |  | 0.03 | Polyketide, Saccharide | komodoquinone B | Streptomyces sp. NRRL S-378
BGC0001851.1 |  | 0.03 | Polyketide, Saccharide | komodoquinone B | Streptomyces erythrochromogenes

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000859.1 |  | 0.61 | Other | ectoine | Methylomicrobium alcaliphilum
BGC0000857.1 |  | 0.54 | Other | ectoine | Methylophaga alcalica
BGC0000854.1 |  | 0.54 | Other | ectoine | Methylomicrobium alcaliphilum 20Z
BGC0000913.1 |  | 0.45 | Other | MK-8 | Enterobacter cloacae
BGC0000903.1 |  | 0.44 | Other | fluorometabolite | Streptomyces cattleya
BGC0001778.1 |  | 0.41 | Other | showdomycin | Streptomyces showdoensis
BGC0000343.1 |  | 0.23 | NRP | enterobactin | Pseudomonas sp. J465
BGC0001073.1 |  | 0.19 | NRP, Polyketide | kosinostatin | Micromonospora sp. TP-A0468
BGC0001852.1 |  | 0.15 | Polyketide, Saccharide | komodoquinone B | Streptomyces sp. NRRL S-378
BGC0001851.1 |  | 0.15 | Polyketide, Saccharide | komodoquinone B | Streptomyces erythrochromogenes

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_GG667196.1 - Region 1 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 35,398 - 56,249 nt. (total: 20,852 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000647.1 |  | 0.32 | Terpene | carotenoid | Rhodobacter sphaeroides
BGC0000645.1 |  | 0.31 | Terpene | carotenoid | Halobacillus halophilus DSM 2266
BGC0000648.1 |  | 0.31 | Terpene | carotenoid | Myxococcus xanthus
BGC0000637.1 |  | 0.30 | Terpene | carotenoid | Corynebacterium glutamicum
BGC0000650.1 |  | 0.22 | Terpene | carotenoid | Algoriphagus sp. KK10202C
BGC0000644.1 |  | 0.21 | Terpene | carotenoid | Dietzia sp. CQ4
BGC0001227.1 |  | 0.21 | Terpene | isorenieratene | Streptomyces collinus Tu 365
BGC0000633.1 |  | 0.21 | Terpene | carotenoid | Streptomyces avermitilis
BGC0000664.1 |  | 0.21 | Terpene | isorenieratene | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001862.1 |  | 0.21 | RiPP | geocillicin | Aeribacillus pallidus

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000647.1 |  | 0.65 | Terpene | carotenoid | Rhodobacter sphaeroides
BGC0000645.1 |  | 0.65 | Terpene | carotenoid | Halobacillus halophilus DSM 2266
BGC0000648.1 |  | 0.65 | Terpene | carotenoid | Myxococcus xanthus
BGC0000637.1 |  | 0.64 | Terpene | carotenoid | Corynebacterium glutamicum
BGC0000650.1 |  | 0.55 | Terpene | carotenoid | Algoriphagus sp. KK10202C
BGC0000644.1 |  | 0.54 | Terpene | carotenoid | Dietzia sp. CQ4
BGC0001227.1 |  | 0.54 | Terpene | isorenieratene | Streptomyces collinus Tu 365
BGC0000633.1 |  | 0.53 | Terpene | carotenoid | Streptomyces avermitilis
BGC0000664.1 |  | 0.53 | Terpene | isorenieratene | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001862.1 |  | 0.53 | RiPP | geocillicin | Aeribacillus pallidus

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_GG667193.1 - Region 1 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 49,281 - 94,059 nt. (total: 44,779 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
NRPS/PKS modules
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | T1PKS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000099.1 |  | 0.26 | Polyketide | monascorubrin | Talaromyces marneffei
BGC0001831.1 |  | 0.24 | Polyketide | alkylpyrone-407, alkylpyrone-393 | Myxococcus xanthus DK 1622
BGC0000056.1 |  | 0.23 | Polyketide | esperamicin | Actinomadura verrucosospora
BGC0001338.1 |  | 0.23 | Polyketide | citrinin | Monascus ruber
BGC0000865.1 |  | 0.23 | Other | eicoseicosapentaenoic acid | Photobacterium profundum SS9
BGC0000027.1 |  | 0.23 | Polyketide | ankaflavin, monascin, rubropunctatine, monascorubrin | Monascus pilosus
BGC0000863.1 |  | 0.22 | Other | eicosapentaenoic acid | Pseudoalteromonas sp. DS-12
BGC0000861.1 |  | 0.22 | Other | eicosapentaenoic acid | Shewanella sp. BR-2
BGC0000862.1 |  | 0.22 | Other | eicosapentaenoic acid | Shewanella pneumatophori
BGC0000154.1 |  | 0.22 | Polyketide | stipitatic acid | Talaromyces stipitatus ATCC 10500

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000099.1 |  | 0.59 | Polyketide | monascorubrin | Talaromyces marneffei
BGC0001831.1 |  | 0.57 | Polyketide | alkylpyrone-407, alkylpyrone-393 | Myxococcus xanthus DK 1622
BGC0000056.1 |  | 0.56 | Polyketide | esperamicin | Actinomadura verrucosospora
BGC0001338.1 |  | 0.56 | Polyketide | citrinin | Monascus ruber
BGC0000865.1 |  | 0.56 | Other | eicoseicosapentaenoic acid | Photobacterium profundum SS9
BGC0000027.1 |  | 0.56 | Polyketide | ankaflavin, monascin, rubropunctatine, monascorubrin | Monascus pilosus
BGC0000863.1 |  | 0.55 | Other | eicosapentaenoic acid | Pseudoalteromonas sp. DS-12
BGC0000861.1 |  | 0.55 | Other | eicosapentaenoic acid | Shewanella sp. BR-2
BGC0000862.1 |  | 0.55 | Other | eicosapentaenoic acid | Shewanella pneumatophori
BGC0000154.1 |  | 0.55 | Polyketide | stipitatic acid | Talaromyces stipitatus ATCC 10500

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Module view
Shows module structures for each candidate in NRPS- and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here.
Legend
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 49280 - 94059:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (mal)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg17_64: pk
  CAL_domain (65..514): pk
  minowa: Acetyl-CoA
  Prediction, score:
    Acetyl-CoA: 26.6
    AHBA: 17.1
    shikimic_acid: 15.6
    NH2: 6.2
    fatty_acid: 0.0
ctg17_65: mal
  PKS_AT (637..931): mal
  ATSignature: Malonyl-CoA
  Top 3 matches:
    Malonyl-CoA: 58.3%
  minowa: fatty_acid
  Prediction, score:
    fatty_acid: 109.4
    Methylmalonyl-CoA: 71.9
    Methoxymalonyl-CoA: 70.3
    Malonyl-CoA: 60.7
    Propionyl-CoA: 49.0
    Ethylmalonyl-CoA: 48.3
    2-Methylbutyryl-CoA: 38.7
    trans-1,2-CPDA: 33.4
    Isobutyryl-CoA: 24.4
    CHC-CoA: 24.4
    Acetyl-CoA: 22.7
    inactive: 20.4
    Benzoyl-CoA: 11.7
    3-Methylbutyryl-CoA: 0.0

NZ_GG667193.1 - Region 2 - NAPAA
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 185,502 - 219,278 nt. (total: 33,777 nt) Show pHMM detection rules used
NAPAA: (AMP-binding and PP-binding and TIGR02353)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
NRPS/PKS modules
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | NAPAA | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000889.1 |  | 0.23 | Other | bagremycin A, bagremycin B | Streptomyces sp. WK-5344
BGC0002029.1 |  | 0.20 | Other | bagremycin A, bagremycin B, bagremycin C, bagremycin E, bagremycin F, bagremycin G, ferroverdin A, ferroverdin B, ferroverdin C | Streptomyces lunaelactis
BGC0001592.1 |  | 0.20 | Other | ferroverdin | Streptomyces lunaelactis
BGC0000427.1 |  | 0.20 | NRP | shinorine, 4-deoxygadusol, mycosporine glycine | Trichormus variabilis ATCC 29413
BGC0001758.1 |  | 0.18 | NRP | rhizomide A, rhizomide B, rhizomide C | Paraburkholderia rhizoxinica HKI 454
BGC0001128.1 |  | 0.18 | NRP | luminmide | Photorhabdus laumondii subsp. laumondii TTO1
BGC0001641.1 |  | 0.18 | NRP | kolossin | Photorhabdus laumondii subsp. laumondii TTO1
BGC0001844.1 |  | 0.18 | NRP | holrhizin | Paraburkholderia rhizoxinica HKI 454
BGC0001135.1 |  | 0.18 | NRP | bicornutin A1, bicornutin A2 | Xenorhabdus budapestensis
BGC0001479.1 |  | 0.18 | NRP | anabaenopeptin NZ857, nostamide A | Nostoc punctiforme PCC 73102

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000889.1 |  | 0.56 | Other | bagremycin A, bagremycin B | Streptomyces sp. WK-5344
BGC0002029.1 |  | 0.53 | Other | bagremycin A, bagremycin B, bagremycin C, bagremycin E, bagremycin F, bagremycin G, ferroverdin A, ferroverdin B, ferroverdin C | Streptomyces lunaelactis
BGC0001592.1 |  | 0.53 | Other | ferroverdin | Streptomyces lunaelactis
BGC0000427.1 |  | 0.53 | NRP | shinorine, 4-deoxygadusol, mycosporine glycine | Trichormus variabilis ATCC 29413
BGC0001758.1 |  | 0.50 | NRP | rhizomide A, rhizomide B, rhizomide C | Paraburkholderia rhizoxinica HKI 454
BGC0001128.1 |  | 0.50 | NRP | luminmide | Photorhabdus laumondii subsp. laumondii TTO1
BGC0001641.1 |  | 0.50 | NRP | kolossin | Photorhabdus laumondii subsp. laumondii TTO1
BGC0001844.1 |  | 0.49 | NRP | holrhizin | Paraburkholderia rhizoxinica HKI 454
BGC0001135.1 |  | 0.49 | NRP | bicornutin A1, bicornutin A2 | Xenorhabdus budapestensis
BGC0001479.1 |  | 0.49 | NRP | anabaenopeptin NZ857, nostamide A | Nostoc punctiforme PCC 73102

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Module view
Shows module structures for each candidate in NRPS- and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here.
Legend
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 2, location 185501 - 219278:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (X)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg17_183: X
  Search NORINE for peptide: strict or relaxed
  AMP-binding (21..383): X
  NRPSPredictor2: (unknown)
  SVM prediction details:
    Predicted physicochemical class:
      hydrophilic
    Large clusters prediction:
      N/A
    Small clusters prediction:
      N/A
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DAESIGtVvK
    Nearest Stachelhaus code:
      lys
    Stachelhaus code match:
      80% (moderate)

NZ_GG667191.1 - Region 1 - lanthipeptide-class-i
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 83,558 - 109,876 nt. (total: 26,319 nt) Show pHMM detection rules used
lanthipeptide-class-i: ((LANC_like and (Lant_dehydr_N or Lant_dehydr_C)) and not (YcaO or TIGR03882))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Lanthipeptides
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | lanthipeptide-class-i | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000556.1 |  | 0.31 | RiPP | streptin | Streptococcus pyogenes
BGC0000541.1 |  | 0.30 | RiPP | paenicidin A | Paenibacillus polymyxa
BGC0000536.1 |  | 0.30 | RiPP | nisin Q | Lactococcus lactis
BGC0001789.1 |  | 0.30 | RiPP | suicin 90-1330 | Streptococcus suis
BGC0000537.1 |  | 0.30 | RiPP | nisin U | Streptococcus uberis
BGC0000542.1 |  | 0.30 | RiPP | paenicidin B | Paenibacillus terrae
BGC0000535.1 |  | 0.30 | RiPP | nisin A | Lactococcus lactis subsp. lactis
BGC0000549.1 |  | 0.26 | RiPP | salivaricin D | Streptococcus salivarius
BGC0001727.1 |  | 0.25 | RiPP | paenilan | Paenibacillus polymyxa E681
BGC0000563.1 |  | 0.25 | RiPP | venezuelin | Streptomyces venezuelae ATCC 10712

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000556.1 |  | 0.65 | RiPP | streptin | Streptococcus pyogenes
BGC0000541.1 |  | 0.64 | RiPP | paenicidin A | Paenibacillus polymyxa
BGC0000536.1 |  | 0.64 | RiPP | nisin Q | Lactococcus lactis
BGC0001789.1 |  | 0.64 | RiPP | suicin 90-1330 | Streptococcus suis
BGC0000537.1 |  | 0.63 | RiPP | nisin U | Streptococcus uberis
BGC0000542.1 |  | 0.63 | RiPP | paenicidin B | Paenibacillus terrae
BGC0000535.1 |  | 0.63 | RiPP | nisin A | Lactococcus lactis subsp. lactis
BGC0000549.1 |  | 0.59 | RiPP | salivaricin D | Streptococcus salivarius
BGC0001727.1 |  | 0.59 | RiPP | paenilan | Paenibacillus polymyxa E681
BGC0000563.1 |  | 0.58 | RiPP | venezuelin | Streptomyces venezuelae ATCC 10712

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Lanthipeptide predictions
Lists the possible core peptides for each biosynthetic enzyme, including the predicted class. Each core peptide shows the leader and core peptide sequences, separated by a dash.

#### Lanthipeptide(s) for ctg19_91 - Putative Class I

ctg19_85 leader / core peptide
  MSDFTLDFAEGDAADTVSPQ - IDhb DhaKDhaLC DhbPGCIDhbGWMMCNDhbVDhbKGC DhaFDhbIGK

#### Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
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Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
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Lanthipeptides
Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists the number of lanthionine bridges, possible molecular weights, and the scores for cleavage site prediction and RODEO.

ctg19_85 - Class I
  Cleavage pHMM score: 4.80
  RODEO score: 28
  Monoisotopic mass: 3105.5 Da
  Molecular weight: 3107.7 Da
  Number of bridges: 4
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3125.8 Da N = 1
    3143.8 Da N = 2
    3161.8 Da N = 3
    3179.8 Da N = 4
    3197.8 Da N = 5