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Overview
1.1
1.2
1.3
2.1
2.2
5.1

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_RBIZ01000003 (original name was: NZ_RBIZ01000003.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | siderophore | 1,545,597 | 1,560,025 | aerobactin | Other | 66%
Region 1.2 | thiopeptide | 1,913,584 | 1,939,888 | O-antigen | Saccharide | 14%
Region 1.3 | NRPS | 2,213,098 | 2,256,964 | turnerbactin | NRP | 30%

NZ_RBIZ01000004 (original name was: NZ_RBIZ01000004.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 2.1 | butyrolactone | 102,756 | 113,745 |
Region 2.2 | thioamitides,RiPP-like | 511,832 | 533,651 |

NZ_RBIZ01000007 (original name was: NZ_RBIZ01000007.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 5.1 | arylpolyene | 38,059 | 81,655 | aryl polyenes | Other | 100%

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | siderophore | 1,545,597 | 1,560,025 | aerobactin | Other | 66%
Region 1.2 | thiopeptide | 1,913,584 | 1,939,888 | O-antigen | Saccharide | 14%
Region 1.3 | NRPS | 2,213,098 | 2,256,964 | turnerbactin | NRP | 30%
Region 2.1 | butyrolactone | 102,756 | 113,745 |
Region 2.2 | thioamitides,RiPP-like | 511,832 | 533,651 |
Region 5.1 | arylpolyene | 38,059 | 81,655 | aryl polyenes | Other | 100%

No secondary metabolite regions were found in these records:
  NZ_RBIZ01000005 (original name was: NZ_RBIZ01000005.1)
  NZ_RBIZ01000006 (original name was: NZ_RBIZ01000006.1)
  NZ_RBIZ01000008 (original name was: NZ_RBIZ01000008.1)
  NZ_RBIZ01000009 (original name was: NZ_RBIZ01000009.1)
  NZ_RBIZ01000010 (original name was: NZ_RBIZ01000010.1)
  NZ_RBIZ01000011 (original name was: NZ_RBIZ01000011.1)
  NZ_RBIZ01000001 (original name was: NZ_RBIZ01000001.1)
  NZ_RBIZ01000002 (original name was: NZ_RBIZ01000002.1)

Compact view
c00001_NZ_RBIZ.. - Region 1 - siderophore
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,545,597 - 1,560,025 nt. (total: 14,429 nt) Show pHMM detection rules used
siderophore: IucA_IucC

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | siderophore | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001499.1 |  | 0.56 | Other | aerobactin | Pantoea ananatis
BGC0001498.1 |  | 0.36 | Other | aerobactin | Xenorhabdus szentirmaii DSM 16338
BGC0001713.1 |  | 0.30 | Other | ochrobactin | Ochrobactrum anthropi
BGC0001572.1 |  | 0.29 | Other | desferrioxamine E | Pantoea agglomerans
BGC0000939.1 |  | 0.26 | Other | aerobactin | Grimontia hollisae
BGC0001555.1 |  | 0.26 | RiPP | colicin V | Escherichia coli chi7122
BGC0000942.1 |  | 0.26 | Other | petrobactin | Bacillus anthracis str. Ames
BGC0001478.1 |  | 0.22 | Other | desferrioxamine E | Streptomyces sp. ID38640
BGC0000941.1 |  | 0.21 | Other | desferrioxamin B | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001453.1 |  | 0.21 | Other | desferrioxamine | Streptomyces argillaceus

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001499.1 |  | 0.82 | Other | aerobactin | Pantoea ananatis
BGC0001498.1 |  | 0.69 | Other | aerobactin | Xenorhabdus szentirmaii DSM 16338
BGC0001713.1 |  | 0.64 | Other | ochrobactin | Ochrobactrum anthropi
BGC0001572.1 |  | 0.63 | Other | desferrioxamine E | Pantoea agglomerans
BGC0000939.1 |  | 0.59 | Other | aerobactin | Grimontia hollisae
BGC0001555.1 |  | 0.59 | RiPP | colicin V | Escherichia coli chi7122
BGC0000942.1 |  | 0.59 | Other | petrobactin | Bacillus anthracis str. Ames
BGC0001478.1 |  | 0.55 | Other | desferrioxamine E | Streptomyces sp. ID38640
BGC0000941.1 |  | 0.54 | Other | desferrioxamin B | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001453.1 |  | 0.54 | Other | desferrioxamine | Streptomyces argillaceus

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00001_NZ_RBIZ.. - Region 2 - thiopeptide
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,913,584 - 1,939,888 nt. (total: 26,305 nt) Show pHMM detection rules used
thiopeptide: ((YcaO or TIGR03882) and ((thio_amide and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N or PF07366 or PF06968 or PF04055) or thiostrepton)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Thiopeptides
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | thiopeptide | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000784.1 |  | 0.24 | Saccharide | O-antigen | Pseudomonas aeruginosa
BGC0000781.1 |  | 0.16 | Saccharide | O-antigen | Pseudomonas aeruginosa
BGC0001285.1 |  | 0.12 | Other (Fatty acid) | pseudopyronine A, pseudopyronine B | Pseudomonas putida
BGC0001441.1 |  | 0.09 | Other | belactosin A, belactosin C | Streptomyces sp.
BGC0000981.1 |  | 0.07 | NRP, Polyketide | cylindrospermopsin | Aphanizomenon sp. 10E6
BGC0001302.1 |  | 0.07 | Other | lomofungin | Streptomyces lomondensis
BGC0002012.1 |  | 0.06 | Polyketide | julichrome Q3-3, julichrome Q3-5 | Streptomyces afghaniensis 772
BGC0001283.1 |  | 0.06 | Polyketide | arsono-polyketide | Streptomyces lividans 1326
BGC0000957.1 |  | 0.05 | NRP, Polyketide | mycotrienin I | Streptomyces sp. XZQH13
BGC0000123.1 |  | 0.03 | Polyketide | phoslactomycin B | Streptomyces sp. HK803

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000784.1 |  | 0.58 | Saccharide | O-antigen | Pseudomonas aeruginosa
BGC0000781.1 |  | 0.47 | Saccharide | O-antigen | Pseudomonas aeruginosa
BGC0001285.1 |  | 0.39 | Other (Fatty acid) | pseudopyronine A, pseudopyronine B | Pseudomonas putida
BGC0001441.1 |  | 0.33 | Other | belactosin A, belactosin C | Streptomyces sp.
BGC0000981.1 |  | 0.28 | NRP, Polyketide | cylindrospermopsin | Aphanizomenon sp. 10E6
BGC0001302.1 |  | 0.28 | Other | lomofungin | Streptomyces lomondensis
BGC0002012.1 |  | 0.25 | Polyketide | julichrome Q3-3, julichrome Q3-5 | Streptomyces afghaniensis 772
BGC0001283.1 |  | 0.25 | Polyketide | arsono-polyketide | Streptomyces lividans 1326
BGC0000957.1 |  | 0.22 | NRP, Polyketide | mycotrienin I | Streptomyces sp. XZQH13
BGC0000123.1 |  | 0.17 | Polyketide | phoslactomycin B | Streptomyces sp. HK803

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Thiopeptide predictions
Lists the possible core peptides for each biosynthetic enzyme, including the predicted class. Each core peptide shows the leader and core peptide sequences, separated by a dash. Predicted tail sequences are also shown.
No core peptides found.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
Thiopeptides
Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists its possible molecular weights and the scores for cleavage site prediction and RODEO. If relevant, other features, such as macrocycle and amidation, will also be listed.
No core peptides found.
c00001_NZ_RBIZ.. - Region 3 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,213,098 - 2,256,964 nt. (total: 43,867 nt) Show pHMM detection rules used
NRPS: cds(Condensation and (AMP-binding or A-OX))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
NRPS/PKS modules
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | NRPS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001185.1 |  | 0.34 | NRP | bacillibactin | Bacillus velezensis FZB42
BGC0001615.1 |  | 0.32 | NRP | hexose-palythine-serine, hexose-shinorine | Heteroscytonema crispum UCFS10
BGC0000401.1 |  | 0.29 | NRP | paenibactin | Paenibacillus elgii B69
BGC0001302.1 |  | 0.25 | Other | lomofungin | Streptomyces lomondensis
BGC0001833.1 |  | 0.24 | NRP | icosalide A, icosalide B | Burkholderia gladioli
BGC0001831.1 |  | 0.24 | Polyketide | alkylpyrone-407, alkylpyrone-393 | Myxococcus xanthus DK 1622
BGC0001844.1 |  | 0.24 | NRP | holrhizin | Paraburkholderia rhizoxinica HKI 454
BGC0001132.1 |  | 0.23 | NRP | xenotetrapeptide | Xenorhabdus nematophila ATCC 19061
BGC0001758.1 |  | 0.23 | NRP | rhizomide A, rhizomide B, rhizomide C | Paraburkholderia rhizoxinica HKI 454
BGC0001149.1 |  | 0.23 | NRP, Saccharide | brabantamide A | Pseudomonas sp. SHC52

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001185.1 |  | 0.67 | NRP | bacillibactin | Bacillus velezensis FZB42
BGC0001615.1 |  | 0.65 | NRP | hexose-palythine-serine, hexose-shinorine | Heteroscytonema crispum UCFS10
BGC0000401.1 |  | 0.63 | NRP | paenibactin | Paenibacillus elgii B69
BGC0001302.1 |  | 0.58 | Other | lomofungin | Streptomyces lomondensis
BGC0001833.1 |  | 0.58 | NRP | icosalide A, icosalide B | Burkholderia gladioli
BGC0001831.1 |  | 0.57 | Polyketide | alkylpyrone-407, alkylpyrone-393 | Myxococcus xanthus DK 1622
BGC0001844.1 |  | 0.57 | NRP | holrhizin | Paraburkholderia rhizoxinica HKI 454
BGC0001132.1 |  | 0.56 | NRP | xenotetrapeptide | Xenorhabdus nematophila ATCC 19061
BGC0001758.1 |  | 0.56 | NRP | rhizomide A, rhizomide B, rhizomide C | Paraburkholderia rhizoxinica HKI 454
BGC0001149.1 |  | 0.56 | NRP, Saccharide | brabantamide A | Pseudomonas sp. SHC52

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Module view
Shows module structures for each candidate in NRPS- and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here.
Legend
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 3, location 2213097 - 2256964:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (ser)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg1_2113: dhb
  Search NORINE for peptide: strict or relaxed
  AMP-binding (35..437): dhb
  NRPSPredictor2: dhb
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aromatic
    Large clusters prediction:
      dhb, sal
    Small clusters prediction:
      dhb, sal
    Single AA prediction:
      dhb
  Stachelhaus prediction details:
    Stachelhaus sequence:
      PMPAQGVVNK
    Nearest Stachelhaus code:
      dhb
    Stachelhaus code match:
      100% (strong)
ctg1_2120: ser
  Search NORINE for peptide: strict or relaxed
  AMP-binding (460..858): ser
  NRPSPredictor2: ser
  SVM prediction details:
    NOTE: outside applicability domain
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      ser, thr, dhpg, hpg
    Small clusters prediction:
      ser
    Single AA prediction:
      ser
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DVWHFSLVDK
    Nearest Stachelhaus code:
      ser
    Stachelhaus code match:
      100% (strong)

c00002_NZ_RBIZ.. - Region 1 - butyrolactone
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 102,756 - 113,745 nt. (total: 10,990 nt) Show pHMM detection rules used
butyrolactone: AfsA

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | butyrolactone | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000849.1 |  | 0.23 | Other (Butyrolactone) | SCB1, SCB2, SCB3 | Streptomyces coelicolor A3(2)
BGC0001310.1 |  | 0.21 | Terpene | naringenin | Streptomyces clavuligerus ATCC 27064
BGC0000850.1 |  | 0.21 | Other | γ-butyrolactone | Streptomyces acidiscabies
BGC0001485.1 |  | 0.14 | Other | 3-demethylchuangxinmycin | Actinoplanes tsinanensis
BGC0001546.1 |  | 0.14 | Alkaloid | chuangxinmycin | Actinoplanes tsinanensis
BGC0001783.1 |  | 0.14 | Other | streptonigrin | Streptomyces flocculus
BGC0000666.1 |  | 0.13 | Terpene | xiamycin A | Streptomyces sp. SCSIO 02999
BGC0000665.1 |  | 0.13 | Terpene, Alkaloid | xiamycin | Streptomyces sp. HKI0576
BGC0001140.1 |  | 0.13 | Terpene | platensimycin, platencin | Streptomyces platensis
BGC0002009.1 |  | 0.13 | Polyketide | kanglemycin A, kanglemycin V1, kanglemycin V2 | Amycolatopsis vancoresmycina

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000849.1 |  | 0.56 | Other (Butyrolactone) | SCB1, SCB2, SCB3 | Streptomyces coelicolor A3(2)
BGC0001310.1 |  | 0.53 | Terpene | naringenin | Streptomyces clavuligerus ATCC 27064
BGC0000850.1 |  | 0.53 | Other | γ-butyrolactone | Streptomyces acidiscabies
BGC0001485.1 |  | 0.44 | Other | 3-demethylchuangxinmycin | Actinoplanes tsinanensis
BGC0001546.1 |  | 0.44 | Alkaloid | chuangxinmycin | Actinoplanes tsinanensis
BGC0001783.1 |  | 0.43 | Other | streptonigrin | Streptomyces flocculus
BGC0000666.1 |  | 0.42 | Terpene | xiamycin A | Streptomyces sp. SCSIO 02999
BGC0000665.1 |  | 0.42 | Terpene, Alkaloid | xiamycin | Streptomyces sp. HKI0576
BGC0001140.1 |  | 0.42 | Terpene | platensimycin, platencin | Streptomyces platensis
BGC0002009.1 |  | 0.42 | Polyketide | kanglemycin A, kanglemycin V1, kanglemycin V2 | Amycolatopsis vancoresmycina

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00002_NZ_RBIZ.. - Region 2 - RiPP-like,thioamitides
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 511,832 - 533,651 nt. (total: 21,820 nt) Show pHMM detection rules used
thioamitides: ((YcaO or TIGR03882) and TfuA)
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | thioamitides | RiPP-like | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | --- | ---
BGC0001849.1 |  |  | 0.43 | RiPP | thiovarsolin A, thiovarsolin B, thiovarsolin C, thiovarsolin D | Streptomyces varsoviensis
BGC0000925.1 |  |  | 0.37 | Other | quinolobactin | Pseudomonas fluorescens
BGC0000917.1 |  |  | 0.35 | Other | molybdenum cofactor | Rhodobacter capsulatus
BGC0001802.1 |  |  | 0.32 | RiPP | thioholgamide A, thioholgamide B | Streptomyces malaysiense
BGC0001696.1 |  |  | 0.32 | RiPP | neothioviridamide | Streptomyces sp.
BGC0000887.1 |  |  | 0.28 | Alkaloid | saxitoxin, gonyautoxin 2, gonyautoxin 3, toxin C2, toxin C3, gonyautoxin 5, decarbamoylsaxitoxin, decarbamoylgonyautoxin 2, decarbamoylgonyautoxin 3 | Dolichospermum circinale AWQC131C
BGC0001488.1 |  |  | 0.28 | Other | 4-formylaminooxyvinylglycine | Pseudomonas fluorescens WH6
BGC0001540.1 |  |  | 0.27 | Other | CC-1065 | Streptomyces zelensis
BGC0000928.1 |  |  | 0.27 | Other | T3 toxin | Cylindrospermopsis raciborskii T3
BGC0000188.1 |  |  | 0.27 | Alkaloid | saxitoxin, neosaxitoxin, decarbamoylsaxitoxin, gonyautoxin 3, gonyautoxin 2 | Cylindrospermopsis raciborskii T3

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001849.1 |  | 0.55 | RiPP | thiovarsolin A, thiovarsolin B, thiovarsolin C, thiovarsolin D | Streptomyces varsoviensis
BGC0000925.1 |  | 0.50 | Other | quinolobactin | Pseudomonas fluorescens
BGC0000917.1 |  | 0.49 | Other | molybdenum cofactor | Rhodobacter capsulatus
BGC0001802.1 |  | 0.47 | RiPP | thioholgamide A, thioholgamide B | Streptomyces malaysiense
BGC0001696.1 |  | 0.47 | RiPP | neothioviridamide | Streptomyces sp.
BGC0000887.1 |  | 0.43 | Alkaloid | saxitoxin, gonyautoxin 2, gonyautoxin 3, toxin C2, toxin C3, gonyautoxin 5, decarbamoylsaxitoxin, decarbamoylgonyautoxin 2, decarbamoylgonyautoxin 3 | Dolichospermum circinale AWQC131C
BGC0001488.1 |  | 0.43 | Other | 4-formylaminooxyvinylglycine | Pseudomonas fluorescens WH6
BGC0001540.1 |  | 0.42 | Other | CC-1065 | Streptomyces zelensis
BGC0000928.1 |  | 0.42 | Other | T3 toxin | Cylindrospermopsis raciborskii T3
BGC0000188.1 |  | 0.42 | Alkaloid | saxitoxin, neosaxitoxin, decarbamoylsaxitoxin, gonyautoxin 3, gonyautoxin 2 | Cylindrospermopsis raciborskii T3

Similar known gene clusters
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No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
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Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
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c00005_NZ_RBIZ.. - Region 1 - arylpolyene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
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Location: 38,059 - 81,655 nt. (total: 43,597 nt) Show pHMM detection rules used
arylpolyene: (APE_KS1 or APE_KS2)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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Similar gene clusters
Shows careas that are similar to the current region to a reference database.
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Analysis type:

Reference | arylpolyene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002008.1 |  | 0.56 | Other | aryl polyenes | Xenorhabdus doucetiae
BGC0000836.1 |  | 0.56 | Other | APE Ec | Escherichia coli CFT073
BGC0001685.1 |  | 0.54 | Other | N-acyloxyacyl lysine | Raoultella ornithinolytica 10-5246
BGC0000837.1 |  | 0.28 | Other | APE Vf | Aliivibrio fischeri ES114
BGC0001723.1 |  | 0.24 | Polyketide | oviedomycin | Streptomyces antibioticus
BGC0000632.1 |  | 0.24 | Terpene, Saccharide | brasilicardin A | Nocardia terpenica
BGC0001895.1 |  | 0.23 | Polyketide | huanglongmycin A, huanglongmycin B, huanglongmycin C | Streptomyces sp. CB09001
BGC0000237.1 |  | 0.23 | Polyketide | lactonamycin Z | Streptomyces sanglieri
BGC0000234.1 |  | 0.23 | Polyketide | jadomycin | Streptomyces venezuelae ATCC 10712
BGC0000236.1 |  | 0.22 | Polyketide | kinamycin | Streptomyces murayamaensis

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002008.1 |  | 0.82 | Other | aryl polyenes | Xenorhabdus doucetiae
BGC0000836.1 |  | 0.82 | Other | APE Ec | Escherichia coli CFT073
BGC0001685.1 |  | 0.81 | Other | N-acyloxyacyl lysine | Raoultella ornithinolytica 10-5246
BGC0000837.1 |  | 0.62 | Other | APE Vf | Aliivibrio fischeri ES114
BGC0001723.1 |  | 0.58 | Polyketide | oviedomycin | Streptomyces antibioticus
BGC0000632.1 |  | 0.57 | Terpene, Saccharide | brasilicardin A | Nocardia terpenica
BGC0001895.1 |  | 0.57 | Polyketide | huanglongmycin A, huanglongmycin B, huanglongmycin C | Streptomyces sp. CB09001
BGC0000237.1 |  | 0.56 | Polyketide | lactonamycin Z | Streptomyces sanglieri
BGC0000234.1 |  | 0.56 | Polyketide | jadomycin | Streptomyces venezuelae ATCC 10712
BGC0000236.1 |  | 0.55 | Polyketide | kinamycin | Streptomyces murayamaensis

Similar known gene clusters
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Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
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Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
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