LOCUS       c00113_NZ_JMTB..        8163 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_JMTB01000114.1 Trabulsiella guamensis ATCC 49490
            GTGU.assembly.114, whole genome shotgun sequence.
ACCESSION   NZ_JMTB01000114
VERSION     NZ_JMTB01000114
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:51:23
            Original ID  :: NZ_JMTB01000114.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 8163
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..8163
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[2539:3163](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2540..3163
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..8163
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..8163
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             complement(22..528)
                     /locus_tag="ctg113_1"
                     /transl_table=11
                     /translation="MIPLLAVAAWSGTGKTTLLKKLIPALCAAGVRPGLIKHTHHNMDV
                     DTPGKDSYELRKAGAAQTIVASAQRWALMTETPEEPELDLNWLVSRMDASTLDLVLVEG
                     FKHEPVAKIMLFRKGGSHDAKELVLDEHVIAIASDVPLAVQSPVLDLNNTDEIVAFILA
                     WLKQQ"
     aSDomain        complement(37..516)
                     /aSDomain="TIGR00176"
                     /aSTool="tigrfam"
                     /description="mobB: molybdopterin-guanine dinucleotide
                     biosynthesis protein B"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg113_1_0001"
                     /evalue="2.00E-50"
                     /identifier="TIGR00176"
                     /label="ctg113_1"
                     /locus_tag="ctg113_1"
                     /protein_end="164"
                     /protein_start="4"
                     /score="168.8"
                     /tool="antismash"
                     /translation="LAVAAWSGTGKTTLLKKLIPALCAAGVRPGLIKHTHHNMDVDTPG
                     KDSYELRKAGAAQTIVASAQRWALMTETPEEPELDLNWLVSRMDASTLDLVLVEGFKHE
                     PVAKIMLFRKGGSHDAKELVLDEHVIAIASDVPLAVQSPVLDLNNTDEIVAFILAW"
     PFAM_domain     complement(112..516)
                     /aSDomain="MobB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03205.16"
                     /description="Molybdopterin guanine dinucleotide synthesis
                     protein B"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg113_1_0001"
                     /evalue="1.10E-47"
                     /label="ctg113_1"
                     /locus_tag="ctg113_1"
                     /protein_end="139"
                     /protein_start="4"
                     /score="161.4"
                     /tool="antismash"
                     /translation="LAVAAWSGTGKTTLLKKLIPALCAAGVRPGLIKHTHHNMDVDTPG
                     KDSYELRKAGAAQTIVASAQRWALMTETPEEPELDLNWLVSRMDASTLDLVLVEGFKHE
                     PVAKIMLFRKGGSHDAKELVLDEHVIAIASD"
     CDS             complement(525..1112)
                     /locus_tag="ctg113_2"
                     /transl_table=11
                     /translation="VNALGPVTGVILAGGKASRMGGQDKGLLMLNGKPLWKHVADTLAP
                     QVASVVISANRNLEIYQESGLLVIQDGLADYPGPLAGMLSVMQHCSDNEWFLFCPCDTP
                     HIPQTLAACLQDKRHDAPVVWVHDGERDHPTIALMHRRIIPALADYLARGERRVMVFMR
                     ENGGHSVDLSHLKPAFANVNTPEDLARWQEKA"
     aSDomain        complement(546..1094)
                     /aSDomain="TIGR02665"
                     /aSTool="tigrfam"
                     /description="molyb_mobA: molybdenum cofactor
                     guanylyltransferase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg113_2_0002"
                     /evalue="1.30E-67"
                     /identifier="TIGR02665"
                     /label="ctg113_2"
                     /locus_tag="ctg113_2"
                     /protein_end="189"
                     /protein_start="6"
                     /score="225.5"
                     /tool="antismash"
                     /translation="VTGVILAGGKASRMGGQDKGLLMLNGKPLWKHVADTLAPQVASVV
                     ISANRNLEIYQESGLLVIQDGLADYPGPLAGMLSVMQHCSDNEWFLFCPCDTPHIPQTL
                     AACLQDKRHDAPVVWVHDGERDHPTIALMHRRIIPALADYLARGERRVMVFMRENGGHS
                     VDLSHLKPAFANVNTPEDLA"
     PFAM_domain     complement(633..1088)
                     /aSDomain="NTP_transf_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12804.9"
                     /description="MobA-like NTP transferase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg113_2_0002"
                     /evalue="5.90E-34"
                     /label="ctg113_2"
                     /locus_tag="ctg113_2"
                     /protein_end="160"
                     /protein_start="8"
                     /score="117.8"
                     /tool="antismash"
                     /translation="GVILAGGKASRMGGQDKGLLMLNGKPLWKHVADTLAPQVASVVIS
                     ANRNLEIYQESGLLVIQDGLADYPGPLAGMLSVMQHCSDNEWFLFCPCDTPHIPQTLAA
                     CLQDKRHDAPVVWVHDGERDHPTIALMHRRIIPALADYLARGERRVMV"
     PFAM_domain     1182..1439
                     /aSDomain="DUF1040"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06288.15"
                     /description="Protein of unknown function (DUF1040)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg113_3_0003"
                     /evalue="9.90E-46"
                     /label="ctg113_3"
                     /locus_tag="ctg113_3"
                     /protein_end="86"
                     /protein_start="0"
                     /score="154.2"
                     /tool="antismash"
                     /translation="MKCKRLNEVIELLQPAWQKEPELNLMQFLQKLAKESGYDGELADL
                     SDDILIYHLKMRDSSKDAVIPGIQKDYEEDFKTALLRARGV"
     CDS             1182..1451
                     /locus_tag="ctg113_3"
                     /transl_table=11
                     /translation="MKCKRLNEVIELLQPAWQKEPELNLMQFLQKLAKESGYDGELADL
                     SDDILIYHLKMRDSSKDAVIPGIQKDYEEDFKTALLRARGVIKE"
     CDS             1526..2512
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg113_4"
                     /sec_met_domain="APH (E-value: 2.3e-43, bitscore: 140.9,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNDKAFTFQTLHPDTIMDALFDQGIRVDSGLTPLNSYENRVYQFQ
                     DEDRHRYVVKFYRPERWSAEQILEEHQFALELEQDDVPVAAPLVFNHQSLLTHQGFYYA
                     IFPSLGGRQFESDNLDQMEWVGRYLGRIHQTARKKRFVVRPDMGVTEYLIEPRQIFETA
                     PLIPGSLKAAFLAATDSLIDAVMAQWHGRFNTLRLHGDCHAGNILWRDGPLFVDLDDAR
                     NGPAVQDLWMLLNGDKAEQRMQLEMIIEAYEEFNAFNTDEIALIEPLRAMRMVYYLAWL
                     IRRWDDPAFPRNFPWLTGEDYWRKQIATFLEQVKVLQEPPLQLTPMY"
     PFAM_domain     1619..2293
                     /aSDomain="APH"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01636.25"
                     /description="Phosphotransferase enzyme family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg113_4_0004"
                     /evalue="1.30E-42"
                     /label="ctg113_4"
                     /locus_tag="ctg113_4"
                     /protein_end="256"
                     /protein_start="31"
                     /score="146.4"
                     /tool="antismash"
                     /translation="TPLNSYENRVYQFQDEDRHRYVVKFYRPERWSAEQILEEHQFALE
                     LEQDDVPVAAPLVFNHQSLLTHQGFYYAIFPSLGGRQFESDNLDQMEWVGRYLGRIHQT
                     ARKKRFVVRPDMGVTEYLIEPRQIFETAPLIPGSLKAAFLAATDSLIDAVMAQWHGRFN
                     TLRLHGDCHAGNILWRDGPLFVDLDDARNGPAVQDLWMLLNGDKAEQRMQLEMIIEAYE
                     EFN"
     CDS             2540..3163
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR03651"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg113_5"
                     /sec_met_domain="TIGR03651 (E-value: 1.3e-06, bitscore:
                     20.8, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIWLALAGMILAFSASAAQITDGKQYITLDKPVAGEPQVLEFF
                     SFYCPHCYQFEEVLHVSDTVKKKLPEGTKMTKYHVEFLGPLGKEMTQAWAVAMALGVED
                     KITAPMFEAVQKTQTVQTVADIRKVFVDAGVKGEEYDAAWNSFVVKSLVAQQEKAAADL
                     QLQGVPAMFVNGKYQLNPQGMDTSSMDIFVQQYADTAKQLVEKK"
     PFAM_domain     2657..3127
                     /aSDomain="DSBA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01323.22"
                     /description="DSBA-like thioredoxin domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg113_5_0005"
                     /evalue="5.90E-29"
                     /label="ctg113_5"
                     /locus_tag="ctg113_5"
                     /protein_end="196"
                     /protein_start="39"
                     /score="101.3"
                     /tool="antismash"
                     /translation="QVLEFFSFYCPHCYQFEEVLHVSDTVKKKLPEGTKMTKYHVEFLG
                     PLGKEMTQAWAVAMALGVEDKITAPMFEAVQKTQTVQTVADIRKVFVDAGVKGEEYDAA
                     WNSFVVKSLVAQQEKAAADLQLQGVPAMFVNGKYQLNPQGMDTSSMDIFVQQY"
     CDS             complement(3177..4085)
                     /locus_tag="ctg113_6"
                     /transl_table=11
                     /translation="MSRLLALLTLLLSVILTILVTVLCSVPIILAGMIKLLLPVPAVWR
                     SISAFCNFMMYCWCEGLAMLLHLNPWLKWDIEGLEGLNKKNWYLLICNHHSWADIVVLC
                     VLFRKHIPMNKYFLKQQLAWVPFIGLACWALDMPFMRRYSRSYLIRHPERRGKDVETTR
                     RSCEKFRAHPTTIVNFVEGSRFTEEKKRQTRSPYKNLLPPKAAGIAMALNVLGSQFDKL
                     LNVTLCYPENDKTPFFDMISGRLTRIVVRINMEPVAEDLHGDYVNDKNFKRRFQLWLNT
                     LWNEKDIQIEAIKSACKNAGH"
     PFAM_domain     complement(3450..3863)
                     /aSDomain="Acyltransferase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01553.23"
                     /description="Acyltransferase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg113_6_0006"
                     /evalue="6.10E-13"
                     /label="ctg113_6"
                     /locus_tag="ctg113_6"
                     /protein_end="212"
                     /protein_start="74"
                     /score="48.6"
                     /tool="antismash"
                     /translation="DIEGLEGLNKKNWYLLICNHHSWADIVVLCVLFRKHIPMNKYFLK
                     QQLAWVPFIGLACWALDMPFMRRYSRSYLIRHPERRGKDVETTRRSCEKFRAHPTTIVN
                     FVEGSRFTEEKKRQTRSPYKNLLPPKAAGIAMAL"
     CDS             4481..7267
                     /locus_tag="ctg113_7"
                     /transl_table=11
                     /translation="MVQIPQNPLILVDGSSYLYRAYHAFPPLTNSAGEPTGAMYGVLNM
                     LRSLIMQYQPTHAAVVFDAKGKTFRDELFEHYKSHRPPMPDDLRAQIEPLHAMVKAMGL
                     PLMAVSGVEADDVIGTLAREAEKMGRPVLISTGDKDMAQLVTPGITLINTMTNTILGPE
                     EVVTKYGVPPELIIDFLALMGDSSDNIPGVPGVGEKTAQALLQGLGGLDTLFSEPEKIA
                     GLTFRGAKTMAAKLQQNEEMARLSYQLATIKTDVELELTCEQLEVQQPIADELLSLFRK
                     YEFKRWTADVEAGKWLQAKGAKPAAKPQETLVIEAEPEAPVSALSAENYVTILDEETLK
                     SWIEKLKKAPLFAFDTETDSLDNVSANMVGLSFATEPGVAAYVPVAHDYLDAPAQIPRD
                     RVLELLKPLLEDEKSLKVGQNLKYDRGILQNYGIELRGIAYDTMLESYTLDSVAGRHDM
                     DSLSDRWLKHKTITFEEIAGKGKNQLTFNQIALEEAGRYAAEDADVTLQLHLKMWPKLQ
                     QDKGPLNVFQNIEMPLVPVLSRVERNGVKIDPVVLHKHSEEIAKRLVELEQKAHDIAGE
                     PFNLSSTKQLQTILFEKQGIKPLKKTPGGAPSTSEEVLEELALDYPLPKVILEYRGLAK
                     LKSTYTDKLPLMINPKTSRVHTSYHQAVTATGRLSSTDPNLQNIPVRNDEGRRIRQAFI
                     APDDYLIVSADYSQIELRIMAHLSRDKGLLKAFAEGKDIHRATAAEVFGLPLESVTGEQ
                     RRSAKAINFGLIYGMSAFGLSRQLNIPRKESQKYMDLYFERYPGVLEYMERTRAQAKEM
                     GYVETLEGRRLYLPDIKSSNAARRAGAERAAINAPMQGTAADIIKRAMIAVDAWLQKEQ
                     PRVRMIMQVHDELVFEVHKDELEAVSKKIHELMENSTTLDVPLLVEVGSGENWDQAH"
     PFAM_domain     4505..4990
                     /aSDomain="5_3_exonuc_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02739.18"
                     /description="5'-3' exonuclease, N-terminal resolvase-like
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg113_7_0007"
                     /evalue="7.70E-55"
                     /label="ctg113_7"
                     /locus_tag="ctg113_7"
                     /protein_end="170"
                     /protein_start="8"
                     /score="185.2"
                     /tool="antismash"
                     /translation="LILVDGSSYLYRAYHAFPPLTNSAGEPTGAMYGVLNMLRSLIMQY
                     QPTHAAVVFDAKGKTFRDELFEHYKSHRPPMPDDLRAQIEPLHAMVKAMGLPLMAVSGV
                     EADDVIGTLAREAEKMGRPVLISTGDKDMAQLVTPGITLINTMTNTILGPEEVVTKYG"
     aSDomain        4505..7264
                     /aSDomain="TIGR00593"
                     /aSTool="tigrfam"
                     /description="pola: DNA polymerase I"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg113_7_0003"
                     /evalue="3.70E-286"
                     /identifier="TIGR00593"
                     /label="ctg113_7"
                     /locus_tag="ctg113_7"
                     /protein_end="928"
                     /protein_start="8"
                     /score="950.0"
                     /tool="antismash"
                     /translation="LILVDGSSYLYRAYHAFPPLTNSAGEPTGAMYGVLNMLRSLIMQY
                     QPTHAAVVFDAKGKTFRDELFEHYKSHRPPMPDDLRAQIEPLHAMVKAMGLPLMAVSGV
                     EADDVIGTLAREAEKMGRPVLISTGDKDMAQLVTPGITLINTMTNTILGPEEVVTKYGV
                     PPELIIDFLALMGDSSDNIPGVPGVGEKTAQALLQGLGGLDTLFSEPEKIAGLTFRGAK
                     TMAAKLQQNEEMARLSYQLATIKTDVELELTCEQLEVQQPIADELLSLFRKYEFKRWTA
                     DVEAGKWLQAKGAKPAAKPQETLVIEAEPEAPVSALSAENYVTILDEETLKSWIEKLKK
                     APLFAFDTETDSLDNVSANMVGLSFATEPGVAAYVPVAHDYLDAPAQIPRDRVLELLKP
                     LLEDEKSLKVGQNLKYDRGILQNYGIELRGIAYDTMLESYTLDSVAGRHDMDSLSDRWL
                     KHKTITFEEIAGKGKNQLTFNQIALEEAGRYAAEDADVTLQLHLKMWPKLQQDKGPLNV
                     FQNIEMPLVPVLSRVERNGVKIDPVVLHKHSEEIAKRLVELEQKAHDIAGEPFNLSSTK
                     QLQTILFEKQGIKPLKKTPGGAPSTSEEVLEELALDYPLPKVILEYRGLAKLKSTYTDK
                     LPLMINPKTSRVHTSYHQAVTATGRLSSTDPNLQNIPVRNDEGRRIRQAFIAPDDYLIV
                     SADYSQIELRIMAHLSRDKGLLKAFAEGKDIHRATAAEVFGLPLESVTGEQRRSAKAIN
                     FGLIYGMSAFGLSRQLNIPRKESQKYMDLYFERYPGVLEYMERTRAQAKEMGYVETLEG
                     RRLYLPDIKSSNAARRAGAERAAINAPMQGTAADIIKRAMIAVDAWLQKEQPRVRMIMQ
                     VHDELVFEVHKDELEAVSKKIHELMENSTTLDVPLLVEVGSGENWDQAH"
     PFAM_domain     4991..5290
                     /aSDomain="5_3_exonuc"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01367.22"
                     /description="5'-3' exonuclease, C-terminal SAM fold"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg113_7_0008"
                     /evalue="8.20E-30"
                     /label="ctg113_7"
                     /locus_tag="ctg113_7"
                     /protein_end="270"
                     /protein_start="170"
                     /score="103.4"
                     /tool="antismash"
                     /translation="VPPELIIDFLALMGDSSDNIPGVPGVGEKTAQALLQGLGGLDTLF
                     SEPEKIAGLTFRGAKTMAAKLQQNEEMARLSYQLATIKTDVELELTCEQLEVQQP"
     PFAM_domain     5468..6031
                     /aSDomain="DNA_pol_A_exo1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01612.22"
                     /description="3'-5' exonuclease"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg113_7_0009"
                     /evalue="2.60E-42"
                     /label="ctg113_7"
                     /locus_tag="ctg113_7"
                     /protein_end="517"
                     /protein_start="329"
                     /score="144.6"
                     /tool="antismash"
                     /translation="YVTILDEETLKSWIEKLKKAPLFAFDTETDSLDNVSANMVGLSFA
                     TEPGVAAYVPVAHDYLDAPAQIPRDRVLELLKPLLEDEKSLKVGQNLKYDRGILQNYGI
                     ELRGIAYDTMLESYTLDSVAGRHDMDSLSDRWLKHKTITFEEIAGKGKNQLTFNQIALE
                     EAGRYAAEDADVTLQLHLKMWPKLQ"
     PFAM_domain     6134..7255
                     /aSDomain="DNA_pol_A"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00476.22"
                     /description="DNA polymerase family A"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg113_7_0010"
                     /evalue="8.00E-158"
                     /label="ctg113_7"
                     /locus_tag="ctg113_7"
                     /protein_end="925"
                     /protein_start="551"
                     /score="525.5"
                     /tool="antismash"
                     /translation="LHKHSEEIAKRLVELEQKAHDIAGEPFNLSSTKQLQTILFEKQGI
                     KPLKKTPGGAPSTSEEVLEELALDYPLPKVILEYRGLAKLKSTYTDKLPLMINPKTSRV
                     HTSYHQAVTATGRLSSTDPNLQNIPVRNDEGRRIRQAFIAPDDYLIVSADYSQIELRIM
                     AHLSRDKGLLKAFAEGKDIHRATAAEVFGLPLESVTGEQRRSAKAINFGLIYGMSAFGL
                     SRQLNIPRKESQKYMDLYFERYPGVLEYMERTRAQAKEMGYVETLEGRRLYLPDIKSSN
                     AARRAGAERAAINAPMQGTAADIIKRAMIAVDAWLQKEQPRVRMIMQVHDELVFEVHKD
                     ELEAVSKKIHELMENSTTLDVPLLVEVGSGENWD"
ORIGIN
        1 gtctgtcaaa agctcgcagc actattgctg ttttaaccac gccagaatga acgccacaat
       61 ctcgtcagta ttattcaaat ccagaaccgg gctctgaact gccaaaggaa catcactggc
      121 gatggcgatc acatgctcat caagcactaa ttcttttgcg tcgtgactac cgccctttct
      181 gaaaagcata atttttgcca ctggttcgtg cttaaatccc tcgacaagaa ccagatccag
      241 cgtcgaggca tccattctgc tgacgagcca gttaagatcc agctcaggtt cttccggcgt
      301 ttcagtcatg agcgcccagc gttgtgcact ggccacaata gtctgggcgg cgccagcctt
      361 gcgcaattca taactgtcct tacctggcgt atcaacatcc atattgtgat gcgtatgttt
      421 tatcagtcct ggacgcacac cggctgcaca cagcgcaggg attagctttt taagcagggt
      481 tgttttgccc gttccgctcc aggcggcaac cgcaagtagt ggaatcatgc cttctcctgc
      541 cagcgggcga gatcttctgg cgtattcacg tttgcaaacg ctggtttaag gtgactcaaa
      601 tccacactgt gcccgccgtt ttcacgcata aaaaccatta ccctgcgctc gcctcgcgcc
      661 agatagtcag ccaaagccgg aataatacgg cgatgcatta acgcgatagt tggatgatcg
      721 cgttcgccat catgaaccca tacgacaggc gcatcgtgtc gtttatcctg tagacacgct
      781 gccagtgtct gagggatatg aggggtatcg caagggcaaa acaggaacca ttcattgtca
      841 ctgcagtgct gcattaccga aagcataccc gctaatggcc cggggtaatc cgccaggccg
      901 tcctgaataa ccagaagacc actttcctga taaatttcca gatttcggtt agcgctaata
      961 accacagacg cgacctgtgg tgccagtgta tcagcaacat gtttccagag cggtttaccg
     1021 ttcagcatca gcaatccttt atcctggccg cccatgcgcg atgcttttcc tcctgccagt
     1081 atcactccgg tcaccggtcc taatgcattc accagtatcg cctcttttat tgtgggattg
     1141 accctgttac cgtgtctctc tcaagagtaa ggagcacgac catgaaatgt aaacgtctga
     1201 acgaagttat tgaacttctc cagccagcct ggcaaaaaga gccggaactg aatcttatgc
     1261 aatttttgca gaaactggcg aaggagtcag gttatgacgg tgaactggct gatttatccg
     1321 atgatattct gatctatcac ctgaaaatgc gcgactccag caaagatgcc gtcattcctg
     1381 gcattcaaaa agattacgaa gaagacttca aaacggcgct gttacgcgcc cgcggtgtta
     1441 ttaaagagta aaaccttgta agcagagcca ccgaaattgc tgtgaaatga tatcctgaat
     1501 tattcgtatc gttttcggga acaggatgaa cgacaaggct ttcacattcc agacacttca
     1561 cccggatacc atcatggatg cactgtttga tcaggggatt cgggtggatt cgggtctcac
     1621 tcctttaaac agttatgaga accgtgtcta tcaatttcag gatgaagatc gtcaccgtta
     1681 tgtggtgaag ttttatcgtc ctgagcgctg gtccgcagag caaattcttg aagaacatca
     1741 gtttgcactg gagctggagc aggatgacgt ccccgttgcc gcaccgctcg tctttaacca
     1801 tcagagcctg ctgacacatc agggctttta ttacgccata tttcccagcc tcggtgggcg
     1861 ccagtttgag tcggataacc ttgaccagat ggagtgggtt ggacgctatc ttggccggat
     1921 acatcagacc gcgcgtaaaa aacgcttcgt ggtccggccg gatatgggcg tcacagagta
     1981 tctgattgag cctcgccaga ttttcgaaac tgctcccctt attcccggta gcttaaaagc
     2041 ggcttttctt gcagcaacgg attcgctcat tgatgctgtc atggcgcaat ggcatggtcg
     2101 gtttaatacg ctgcgtttac atggtgattg ccatgcaggc aatattctct ggcgcgacgg
     2161 cccgttattt gtggatctcg atgatgcccg caacggcccg gccgtccagg atttatggat
     2221 gctgctaaac ggtgacaaag ctgagcagcg tatgcagctg gagatgatca ttgaagcata
     2281 tgaagaattt aatgccttca ataccgatga gatcgccctc atagaacctt tacgtgccat
     2341 gcgtatggtt tactatctgg catggttgat cagacgctgg gacgatcctg cctttcccag
     2401 aaattttccg tggttaaccg gggaagatta ctggcgtaag cagatcgcaa cttttctaga
     2461 gcaggtgaag gttctgcagg aaccccctct tcaattaacg ccaatgtatt aatttgatat
     2521 ttcaggagag aatgacatca tgaaaaaaat ttggctggcg ctggccggta tgattctggc
     2581 atttagcgca tccgcagcgc agatcaccga cggtaaacaa tacattaccc tcgataagcc
     2641 ggttgcagga gagcctcagg tactcgagtt cttctccttt tattgcccgc actgttatca
     2701 gtttgaggaa gtgttgcacg tttccgatac cgtgaagaaa aagctgccgg aaggcaccaa
     2761 aatgaccaaa tatcacgtcg aattcctcgg accgttgggt aaagagatga cccaggcatg
     2821 ggctgtagcg atggcgctgg gcgtagaaga caaaatcact gcaccgatgt ttgaagctgt
     2881 gcaaaaaaca cagactgtgc agacggtagc agatatccgt aaagtgttcg tggatgccgg
     2941 tgtgaagggt gaagaatacg acgcagcatg gaacagcttt gtggtgaaat cgctggttgc
     3001 tcagcaggaa aaagcggcgg cagatcttca gttgcagggg gtcccggcaa tgttcgttaa
     3061 cggtaaatat cagctgaatc cgcagggcat ggataccagc agtatggata tttttgttca
     3121 gcaatatgcc gacacagcga aacaactggt cgagaagaaa taaacaaaaa cgccggtcaa
     3181 tgaccggcgt ttttacaggc agatttaatc gcttctatct gaatatcttt ttcattccac
     3241 agggtattca gccacagctg gaaacggcgc ttaaaattct tatcgttaac gtagtcaccg
     3301 tgtaaatcct cagccactgg ctccatattg atacgcacca caatccgggt taaccggccg
     3361 gaaatcatat caaaaaacgg tgttttatca ttttccgggt agcacagcgt aacatttaac
     3421 agtttatcga attgcgagcc cagcacgttt aacgccatgg caatacccgc cgcttttggc
     3481 ggtaacagat tcttgtatgg cgaacgtgtc tggcgctttt tctcttcggt aaaacgagag
     3541 ccttccacaa aattcacaat cgtggtggga tgcgcgcgga atttctcaca cgagcggcgt
     3601 gtggtttcga catcttttcc acggcgttcc ggatgacgaa tcagatagct tctggaatag
     3661 cgacgcataa aaggcatatc cagcgcccaa cacgccagac caataaaagg cacccatgcc
     3721 agctgctgtt tcagaaagta tttattcatc ggaatatgct tgcggaacag tacgcacaac
     3781 accacgatat cggcccagct atggtggtta caaatcagca gataccagtt ttttttattc
     3841 agcccttcaa gcccttcaat atcccatttc agccagggat taaggtgcaa cagcatcgcc
     3901 agaccttcac accagcaata catcatgaaa ttgcaaaaag ccgagatcga acgccagacg
     3961 gctggaacgg gcaaaagaag tttaatcatc ccggcaagaa tgatcggcac ggaacacagc
     4021 actgtgacca gaatagtaag aataacgcta agcaggagcg ttaaaagagc gagtaatctc
     4081 gacatagttc attatttcag atagttagcc acacaacgtg ctctgagacc cggcacaggg
     4141 ggctgatttt atcagaaaat gcacactatg atggggcttc gcgggtgaga aaaataaata
     4201 ttacttatat ccacatggaa caaattgtca tcgttttgtt ttatagcggc ttgatcatat
     4261 tataatttat tgaaatattt gacttaattt aatcccccgt gacgttgtga ctatggtttt
     4321 attagtcatc acaattctat gcacaaactt atccacaggt gagttttgcg agcgatcttc
     4381 tggatctgca aatcttctca acaaatgtgg cgaaaaattc atgttttcag tccgtctgtg
     4441 gcatccttta cccctattct gaaaaacagg cacggaaatt atggttcaga tccctcaaaa
     4501 cccactcatt cttgttgatg gctcttccta cctctaccgg gcgtatcatg cgtttcctcc
     4561 gctgacgaac agtgcaggcg aacccaccgg agcgatgtat ggtgtgctga acatgttgcg
     4621 cagcctgatc atgcagtacc agcctaccca tgcggcggtt gtttttgatg cgaaaggtaa
     4681 aaccttccgt gacgaactat ttgaacatta caaatcccat cgcccgccga tgccggacga
     4741 tcttcgtgcg cagatcgagc cactacatgc gatggtaaaa gcaatggggt taccgctgat
     4801 ggctgtctct ggcgttgagg cggatgatgt tatcggcacc ctggcgcgtg aagccgaaaa
     4861 aatgggccgc ccggtgttga tcagcaccgg tgataaagac atggcgcagt tagtcacgcc
     4921 aggtatcacg cttatcaata ccatgaccaa taccatcctt ggtcctgaag aggtggtaac
     4981 gaagtatggc gtaccgccag aacttattat cgatttcctc gcattgatgg gggattcttc
     5041 agataacatc cctggtgtac cgggcgttgg cgagaaaacg gcgcaggcgt tgctgcaagg
     5101 gttaggtggt ctggatacgc tgttttctga gccagaaaaa atcgccgggc tgaccttccg
     5161 tggtgcgaaa accatggcgg cgaagttgca acagaatgag gaaatggccc gtctttccta
     5221 tcaactggct accatcaaaa cggatgttga actggaactg acctgtgaac aactggaagt
     5281 ccagcagccg atcgccgatg aactgttgag cctgttcaga aaatatgaat tcaagcgctg
     5341 gacggcagac gtcgaagctg gcaaatggtt acaggccaaa ggcgccaaac ctgcagcaaa
     5401 accgcaagag acgctggtga ttgaagctga gccagaagca cctgtttcag cactgtcagc
     5461 cgaaaactat gtcaccattc ttgacgaaga gacgctaaaa agctggatcg aaaaactgaa
     5521 aaaagcgccg ctctttgcct tcgatacgga aacagacagc ctggataacg tcagcgccaa
     5581 tatggttggg ctctcttttg caactgaacc tggcgttgcc gcgtatgtgc cggttgccca
     5641 tgattacctc gacgcgccag cgcaaatccc acgagatcgg gttctggaat tattaaaacc
     5701 gctactggaa gatgaaaaga gcctgaaagt ggggcagaac ctgaaatacg accgggggat
     5761 cctgcaaaat tatggcatcg agctgcgtgg tattgcctat gacaccatgc tggaatcgta
     5821 cacgctggac agcgttgcgg gtcgccatga tatggacagc ctttccgatc gctggttgaa
     5881 acacaaaacc atcacttttg aagaaattgc cggtaagggc aaaaatcagc tcacgtttaa
     5941 tcagatagcg cttgaagagg cgggacgtta cgcggcagaa gacgcggatg ttactctgca
     6001 attgcacctg aaaatgtggc cgaagctgca acaggataaa ggaccgctga atgtctttca
     6061 gaacattgaa atgccgctgg tgccagtgct ttcacgcgta gaacgtaacg gcgtaaaaat
     6121 cgaccctgtg gtgctgcaca agcattcaga agagattgct aaacggctgg tggaactgga
     6181 gcagaaggcg cacgacatcg ccggagagcc atttaacctc tcttccacca agcaactgca
     6241 aacgattctg ttcgaaaaac agggcattaa gccgctgaag aaaacacctg gcggtgcgcc
     6301 atcgacgtcg gaagaggtgc tggaagagct ggccctggat tacccgctgc cgaaagtcat
     6361 tctggaatat cgtggtctgg cgaagctgaa atcgacctac accgacaagc tgccgttgat
     6421 gatcaacccg aaaaccagcc gtgtgcacac ctcttatcac caggcggtaa cggcaaccgg
     6481 gcgtttatct tctacagatc cgaacctgca aaatattcct gtgcgtaatg acgaagggcg
     6541 ccgcattcgt caggcattta ttgcccctga cgattacctg atcgtttctg ctgactactc
     6601 gcagattgag ctgcgtatta tggcgcatct gtcgcgtgat aaggggttgc tgaaagcatt
     6661 tgctgagggg aaagacattc accgcgccac ggcggcggaa gtctttggcc tgccgctgga
     6721 gagtgtcact ggcgaacagc gccgcagcgc gaaggcgatc aactttggcc tgatttatgg
     6781 catgagtgcg tttggtttgt cccgtcagct caatattccg cgcaaagagt cgcagaaata
     6841 tatggatctc tacttcgaac gttacccggg cgtactggaa tatatggagc gcacccgcgc
     6901 acaggcgaaa gagatgggct acgttgaaac ccttgaaggg cgtcgcctct atctgccgga
     6961 catcaaatcc agtaacgcgg cgcgtcgcgc tggagcggaa cgtgccgcga ttaacgcacc
     7021 tatgcaagga accgccgcgg atatcattaa gcgtgcaatg atcgctgtgg atgcctggct
     7081 gcaaaaagag caaccccgcg tgcgtatgat catgcaggta cacgatgaac tggtgttcga
     7141 agtgcacaaa gatgagcttg aggcggtatc gaagaaaatt cacgagctga tggaaaacag
     7201 cacaacgctg gatgttccgc tgcttgtgga agtcggtagt ggcgaaaatt gggatcaggc
     7261 ccactaaatc ggctttcctg accgcgattt tttgtaactt agcaacataa cttatcgcat
     7321 tttgtgatgg ttattagaat ttgctatgta aacaatgaaa aaaaactaca aaaagtgctt
     7381 tgttacacgc acaaaaaaga gtagagttac tcgcgtaggg tacagaggta agatgttcta
     7441 tctttcagac cttttacttc acgtaatcgg atttggctga atatttagcc gccccagtca
     7501 tttatgactg gggcgttttt tattgcgcca aagaaaaagc gcgctcagtg ttattcttca
     7561 gccaccgcct cttcgggagg gatgtcgcta aaccagatgt ccagcttctg gcgaagctta
     7621 tccaccccct gttttttcag ggaggagaat acttccacct gcacgtcgcc gttaaaggca
     7681 atcaccgctt cgcgaaccat gttgagctgc gccttacgcg ccccgctggc cagcttgtcg
     7741 gctttcgtca gcagaaccag taccggaatg ttgctgtcta ccgcccactc aatcatctgc
     7801 tgatcgagat ctttcagggg atgacggatg tccatcagca ccaccagacc tttcaggcac
     7861 aggcgttttt ccagatattc acccagtgcg cgttgccatt tccgcttcat ctcttccggt
     7921 acctgggcat aaccgtagcc cggcaggtcg accaggcgct tgccttctgc cgtttcgaac
     7981 agattaatca actgcgtacg gcctggcgtt tttgaggtgc gggccaggtt tttctgattt
     8041 gtcagcgtat tcagggcgct ggatttaccc gcgttggagc ggcctgcaaa cgccacttcg
     8101 atcccggtat cttccggcaa gtggcgaata tccggcgcgc tggtgataaa acgcgtcagt
     8161 tga
//
