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Overview
1.1
1.2
1.3

### Identified secondary metabolite regions using strictness 'relaxed'

NC_002967.9

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1 | RiPP-like | 476,741 | 486,545 |
Region 2 | RiPP-like | 749,267 | 760,365 |
Region 3 | RiPP-like | 2,454,260 | 2,466,416 |

NC_002967.9 - Region 1 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 476,741 - 486,545 nt. (total: 9,805 nt) Show pHMM detection rules used
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RiPP-like | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000558.1 |  | 0.23 | RiPP | sublancin 168 | Bacillus subtilis subsp. subtilis str. 168
BGC0000554.1 |  | 0.21 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0000617.1 |  | 0.19 | RiPP | coagulin | Bacillus coagulans
BGC0000624.1 |  | 0.16 | RiPP | salivaricin CRL1328 α peptide, salivaricin CRL1328 β peptide | Lactobacillus salivarius
BGC0001862.1 |  | 0.16 | RiPP | geocillicin | Aeribacillus pallidus
BGC0001930.1 |  | 0.16 | RiPP | pallidocin | Aeribacillus pallidus
BGC0001863.1 |  | 0.16 | RiPP, Terpene | bacillicn CER074 | Bacillus mycoides
BGC0001639.1 |  | 0.15 | RiPP | klebsidin | Klebsiella pneumoniae
BGC0000500.1 |  | 0.14 | RiPP | carnolysin A1, carnolysin A2 | Carnobacterium maltaromaticum
BGC0000504.1 |  | 0.14 | RiPP | cytolysin ClyLl, cytolysin ClyLs | Plasmid pAD1

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000558.1 |  | 0.56 | RiPP | sublancin 168 | Bacillus subtilis subsp. subtilis str. 168
BGC0000554.1 |  | 0.53 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0000617.1 |  | 0.51 | RiPP | coagulin | Bacillus coagulans
BGC0000624.1 |  | 0.47 | RiPP | salivaricin CRL1328 α peptide, salivaricin CRL1328 β peptide | Lactobacillus salivarius
BGC0001862.1 |  | 0.46 | RiPP | geocillicin | Aeribacillus pallidus
BGC0001930.1 |  | 0.46 | RiPP | pallidocin | Aeribacillus pallidus
BGC0001863.1 |  | 0.46 | RiPP, Terpene | bacillicn CER074 | Bacillus mycoides
BGC0001639.1 |  | 0.45 | RiPP | klebsidin | Klebsiella pneumoniae
BGC0000500.1 |  | 0.44 | RiPP | carnolysin A1, carnolysin A2 | Carnobacterium maltaromaticum
BGC0000504.1 |  | 0.44 | RiPP | cytolysin ClyLl, cytolysin ClyLs | Plasmid pAD1

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NC_002967.9 - Region 2 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 749,267 - 760,365 nt. (total: 11,099 nt) Show pHMM detection rules used
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RiPP-like | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001863.1 |  | 0.21 | RiPP, Terpene | bacillicn CER074 | Bacillus mycoides
BGC0000554.1 |  | 0.21 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0001862.1 |  | 0.20 | RiPP | geocillicin | Aeribacillus pallidus
BGC0001930.1 |  | 0.20 | RiPP | pallidocin | Aeribacillus pallidus
BGC0001861.1 |  | 0.20 | RiPP | bacillicin BAG2O | Bacillus cereus BAG2O-1
BGC0000484.1 |  | 0.20 | RiPP | glycocin F | Lactobacillus plantarum
BGC0000504.1 |  | 0.19 | RiPP | cytolysin ClyLl, cytolysin ClyLs | Plasmid pAD1
BGC0000500.1 |  | 0.19 | RiPP | carnolysin A1, carnolysin A2 | Carnobacterium maltaromaticum
BGC0001407.1 |  | 0.19 | RiPP | bicereucin | Bacillus cereus SJ1
BGC0000617.1 |  | 0.19 | RiPP | coagulin | Bacillus coagulans

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001863.1 |  | 0.53 | RiPP, Terpene | bacillicn CER074 | Bacillus mycoides
BGC0000554.1 |  | 0.53 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0001862.1 |  | 0.53 | RiPP | geocillicin | Aeribacillus pallidus
BGC0001930.1 |  | 0.53 | RiPP | pallidocin | Aeribacillus pallidus
BGC0001861.1 |  | 0.53 | RiPP | bacillicin BAG2O | Bacillus cereus BAG2O-1
BGC0000484.1 |  | 0.52 | RiPP | glycocin F | Lactobacillus plantarum
BGC0000504.1 |  | 0.51 | RiPP | cytolysin ClyLl, cytolysin ClyLs | Plasmid pAD1
BGC0000500.1 |  | 0.51 | RiPP | carnolysin A1, carnolysin A2 | Carnobacterium maltaromaticum
BGC0001407.1 |  | 0.51 | RiPP | bicereucin | Bacillus cereus SJ1
BGC0000617.1 |  | 0.51 | RiPP | coagulin | Bacillus coagulans

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NC_002967.9 - Region 3 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,454,260 - 2,466,416 nt. (total: 12,157 nt) Show pHMM detection rules used
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RiPP-like | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000558.1 |  | 0.23 | RiPP | sublancin 168 | Bacillus subtilis subsp. subtilis str. 168
BGC0000554.1 |  | 0.21 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0000617.1 |  | 0.18 | RiPP | coagulin | Bacillus coagulans
BGC0000624.1 |  | 0.16 | RiPP | salivaricin CRL1328 α peptide, salivaricin CRL1328 β peptide | Lactobacillus salivarius
BGC0001862.1 |  | 0.16 | RiPP | geocillicin | Aeribacillus pallidus
BGC0001930.1 |  | 0.16 | RiPP | pallidocin | Aeribacillus pallidus
BGC0000486.1 |  | 0.16 | RiPP | butyrivibriocin AR10 | Butyrivibrio fibrisolvens
BGC0001861.1 |  | 0.15 | RiPP | bacillicin BAG2O | Bacillus cereus BAG2O-1
BGC0000584.1 |  | 0.15 | RiPP | colicin V | Escherichia coli
BGC0001928.1 |  | 0.15 | Other | (2R,3S,4S)-5-fluoro-2,3,4-trihydroxypentanoic acid | Streptomyces sp. MA37

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000558.1 |  | 0.56 | RiPP | sublancin 168 | Bacillus subtilis subsp. subtilis str. 168
BGC0000554.1 |  | 0.53 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0000617.1 |  | 0.50 | RiPP | coagulin | Bacillus coagulans
BGC0000624.1 |  | 0.47 | RiPP | salivaricin CRL1328 α peptide, salivaricin CRL1328 β peptide | Lactobacillus salivarius
BGC0001862.1 |  | 0.46 | RiPP | geocillicin | Aeribacillus pallidus
BGC0001930.1 |  | 0.46 | RiPP | pallidocin | Aeribacillus pallidus
BGC0000486.1 |  | 0.46 | RiPP | butyrivibriocin AR10 | Butyrivibrio fibrisolvens
BGC0001861.1 |  | 0.45 | RiPP | bacillicin BAG2O | Bacillus cereus BAG2O-1
BGC0000584.1 |  | 0.45 | RiPP | colicin V | Escherichia coli
BGC0001928.1 |  | 0.44 | Other | (2R,3S,4S)-5-fluoro-2,3,4-trihydroxypentanoic acid | Streptomyces sp. MA37

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names