Select genomic region:
Overview
3.1
3.2
3.3
3.4

### Identified secondary metabolite regions using strictness 'relaxed'

c00003_NZ_CABK.. (original name was: NZ_CABKOG010000003.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 3.1 | cyclic-lactone-autoinducer | 286,178 | 304,900 |
Region 3.2 | RRE-containing | 1,574,121 | 1,592,646 |
Region 3.3 | ranthipeptide | 1,944,031 | 1,965,386 |
Region 3.4 | cyclic-lactone-autoinducer | 2,496,250 | 2,516,825 | desotamide | NRP | 9%

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 3.1 | cyclic-lactone-autoinducer | 286,178 | 304,900 |
Region 3.2 | RRE-containing | 1,574,121 | 1,592,646 |
Region 3.3 | ranthipeptide | 1,944,031 | 1,965,386 |
Region 3.4 | cyclic-lactone-autoinducer | 2,496,250 | 2,516,825 | desotamide | NRP | 9%

No secondary metabolite regions were found in these records:
  c00001_NZ_CABK.. (original name was: NZ_CABKOG010000001.1)
  c00002_NZ_CABK.. (original name was: NZ_CABKOG010000002.1)
  c00004_NZ_CABK.. (original name was: NZ_CABKOG010000004.1)
  c00005_NZ_CABK.. (original name was: NZ_CABKOG010000005.1)

Compact view
c00003_NZ_CABK.. - Region 1 - cyclic-lactone-autoinducer
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 286,178 - 304,900 nt. (total: 18,723 nt) Show pHMM detection rules used
cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | cyclic-lactone-autoinducer | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000560.1 |  | 0.15 | RiPP | subtilomycin | Bacillus subtilis
BGC0000602.1 |  | 0.15 | RiPP | subtilosin A | Bacillus subtilis subsp. spizizenii ATCC 6633
BGC0000509.1 |  | 0.15 | RiPP | epilancin 15x | Staphylococcus epidermidis
BGC0000792.1 |  | 0.15 | Saccharide | polysaccharide | Enterococcus faecalis OG1RF
BGC0001891.1 |  | 0.13 | Other | closthioamide | Ruminiclostridium cellulolyticum H10
BGC0001525.1 |  | 0.13 | Other | bartoloside 2, bartoloside 3, bartoloside 4 | Synechocystis salina LEGE 06155
BGC0002009.1 |  | 0.13 | Polyketide | kanglemycin A, kanglemycin V1, kanglemycin V2 | Amycolatopsis vancoresmycina
BGC0001391.1 |  | 0.13 | RiPP | thusin | Bacillus thuringiensis serovar rongseni
BGC0001526.1 |  | 0.13 | Other | bartolosides E, bartolosides F, bartolosides G, bartolosides H, bartolosides I, bartolosides J, bartolosides K | Synechocystis salina LEGE 06099
BGC0000556.1 |  | 0.12 | RiPP | streptin | Streptococcus pyogenes

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000560.1 |  | 0.46 | RiPP | subtilomycin | Bacillus subtilis
BGC0000602.1 |  | 0.46 | RiPP | subtilosin A | Bacillus subtilis subsp. spizizenii ATCC 6633
BGC0000509.1 |  | 0.45 | RiPP | epilancin 15x | Staphylococcus epidermidis
BGC0000792.1 |  | 0.45 | Saccharide | polysaccharide | Enterococcus faecalis OG1RF
BGC0001891.1 |  | 0.42 | Other | closthioamide | Ruminiclostridium cellulolyticum H10
BGC0001525.1 |  | 0.42 | Other | bartoloside 2, bartoloside 3, bartoloside 4 | Synechocystis salina LEGE 06155
BGC0002009.1 |  | 0.42 | Polyketide | kanglemycin A, kanglemycin V1, kanglemycin V2 | Amycolatopsis vancoresmycina
BGC0001391.1 |  | 0.41 | RiPP | thusin | Bacillus thuringiensis serovar rongseni
BGC0001526.1 |  | 0.41 | Other | bartolosides E, bartolosides F, bartolosides G, bartolosides H, bartolosides I, bartolosides J, bartolosides K | Synechocystis salina LEGE 06099
BGC0000556.1 |  | 0.39 | RiPP | streptin | Streptococcus pyogenes

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00003_NZ_CABK.. - Region 2 - RRE-containing
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,574,121 - 1,592,646 nt. (total: 18,526 nt) Show pHMM detection rules used
RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RRE-containing | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001683.1 |  | 0.13 | Other | N-acyl serinol | Bacillus sp. 2_A_57_CT2
BGC0001940.1 |  | 0.07 | Polyketide | pyxidicycline A, pyxidicycline B | Pyxidicoccus fallax
BGC0000993.1 |  | 0.05 | NRP, Polyketide | FR901228 | Chromobacterium violaceum
BGC0000119.1 |  | 0.04 | Polyketide, Saccharide | 7-deoxypactamycin | Streptomyces pactum
BGC0001728.1 |  | 0.04 | NRP, Polyketide | paenilipoheptin | Paenibacillus polymyxa E681
BGC0001558.1 |  | 0.04 | Polyketide | cosmomycin C | Streptomyces sp. CNT302
BGC0000118.1 |  | 0.04 | Polyketide | pactamycin | Streptomyces pactum
BGC0001074.1 |  | 0.03 | Saccharide, Polyketide | cosmomycin D | Streptomyces olindensis
BGC0001568.1 |  | 0.03 | Polyketide | cytorhodin | Streptomyces sp. SCSIO 1666

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001683.1 |  | 0.42 | Other | N-acyl serinol | Bacillus sp. 2_A_57_CT2
BGC0001940.1 |  | 0.29 | Polyketide | pyxidicycline A, pyxidicycline B | Pyxidicoccus fallax
BGC0000993.1 |  | 0.21 | NRP, Polyketide | FR901228 | Chromobacterium violaceum
BGC0000119.1 |  | 0.20 | Polyketide, Saccharide | 7-deoxypactamycin | Streptomyces pactum
BGC0001728.1 |  | 0.19 | NRP, Polyketide | paenilipoheptin | Paenibacillus polymyxa E681
BGC0001558.1 |  | 0.18 | Polyketide | cosmomycin C | Streptomyces sp. CNT302
BGC0000118.1 |  | 0.18 | Polyketide | pactamycin | Streptomyces pactum
BGC0001074.1 |  | 0.16 | Saccharide, Polyketide | cosmomycin D | Streptomyces olindensis
BGC0001568.1 |  | 0.16 | Polyketide | cytorhodin | Streptomyces sp. SCSIO 1666

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00003_NZ_CABK.. - Region 3 - ranthipeptide
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,944,031 - 1,965,386 nt. (total: 21,356 nt) Show pHMM detection rules used
ranthipeptide: (TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085 or SPASM)) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716 or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or YcaO or TIGR03882)))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | ranthipeptide | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000600.1 |  | 0.19 | RiPP | thurincin H | Bacillus thuringiensis
BGC0000523.1 |  | 0.17 | RiPP | lactocin S | Lactobacillus sakei
BGC0001579.1 |  | 0.17 | RiPP | duramycin | Streptomyces cinnamoneus
BGC0000616.1 |  | 0.17 | RiPP | amylocyclicin | Bacillus velezensis FZB42
BGC0000626.1 |  | 0.17 | RiPP | thuricin | Bacillus thuringiensis
BGC0001210.1 |  | 0.16 | RiPP | pseudomycoicidin | Bacillus pseudomycoides DSM 12442
BGC0000521.1 |  | 0.16 | RiPP | lacticin 481 | Lactococcus lactis subsp. lactis
BGC0000539.1 |  | 0.16 | RiPP | nukacin ISK-1 | Staphylococcus warneri
BGC0001779.1 |  | 0.16 | RiPP | siamycin | Streptomyces nodosus
BGC0000599.1 |  | 0.16 | RiPP | thuricin CD α, thuricin CD β | Bacillus thuringiensis

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000600.1 |  | 0.52 | RiPP | thurincin H | Bacillus thuringiensis
BGC0000523.1 |  | 0.48 | RiPP | lactocin S | Lactobacillus sakei
BGC0001579.1 |  | 0.48 | RiPP | duramycin | Streptomyces cinnamoneus
BGC0000616.1 |  | 0.48 | RiPP | amylocyclicin | Bacillus velezensis FZB42
BGC0000626.1 |  | 0.47 | RiPP | thuricin | Bacillus thuringiensis
BGC0001210.1 |  | 0.47 | RiPP | pseudomycoicidin | Bacillus pseudomycoides DSM 12442
BGC0000521.1 |  | 0.47 | RiPP | lacticin 481 | Lactococcus lactis subsp. lactis
BGC0000539.1 |  | 0.47 | RiPP | nukacin ISK-1 | Staphylococcus warneri
BGC0001779.1 |  | 0.46 | RiPP | siamycin | Streptomyces nodosus
BGC0000599.1 |  | 0.46 | RiPP | thuricin CD α, thuricin CD β | Bacillus thuringiensis

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00003_NZ_CABK.. - Region 4 - cyclic-lactone-autoinducer
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,496,250 - 2,516,825 nt. (total: 20,576 nt) Show pHMM detection rules used
cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | cyclic-lactone-autoinducer | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001361.1 |  | 0.23 | Terpene | sodorifen | Serratia plymuthica 4Rx13
BGC0000488.1 |  | 0.20 | RiPP | circularin A | Clostridium beijerinckii
BGC0000600.1 |  | 0.16 | RiPP | thurincin H | Bacillus thuringiensis
BGC0000523.1 |  | 0.16 | RiPP | lactocin S | Lactobacillus sakei
BGC0000521.1 |  | 0.16 | RiPP | lacticin 481 | Lactococcus lactis subsp. lactis
BGC0001210.1 |  | 0.16 | RiPP | pseudomycoicidin | Bacillus pseudomycoides DSM 12442
BGC0001364.1 |  | 0.16 | RiPP | cinnamycin B | Actinomadura atramentaria DSM 43919
BGC0000500.1 |  | 0.16 | RiPP | carnolysin A1, carnolysin A2 | Carnobacterium maltaromaticum
BGC0000489.1 |  | 0.16 | RiPP | enterocin AS-48 | Enterococcus faecalis
BGC0000561.1 |  | 0.16 | RiPP | thermophilin 1277 | Streptococcus thermophilus

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001361.1 |  | 0.57 | Terpene | sodorifen | Serratia plymuthica 4Rx13
BGC0000488.1 |  | 0.52 | RiPP | circularin A | Clostridium beijerinckii
BGC0000600.1 |  | 0.46 | RiPP | thurincin H | Bacillus thuringiensis
BGC0000523.1 |  | 0.46 | RiPP | lactocin S | Lactobacillus sakei
BGC0000521.1 |  | 0.46 | RiPP | lacticin 481 | Lactococcus lactis subsp. lactis
BGC0001210.1 |  | 0.46 | RiPP | pseudomycoicidin | Bacillus pseudomycoides DSM 12442
BGC0001364.1 |  | 0.46 | RiPP | cinnamycin B | Actinomadura atramentaria DSM 43919
BGC0000500.1 |  | 0.46 | RiPP | carnolysin A1, carnolysin A2 | Carnobacterium maltaromaticum
BGC0000489.1 |  | 0.46 | RiPP | enterocin AS-48 | Enterococcus faecalis
BGC0000561.1 |  | 0.46 | RiPP | thermophilin 1277 | Streptococcus thermophilus

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names