LOCUS       NC_018664.1            20591 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_018664.1 Gottschalkia acidurici 9a, complete sequence.
ACCESSION   NC_018664
VERSION     NC_018664.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:41:59
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1501488
            Orig. end    :: 1522079
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..20591
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[1511488:1512079](+)"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10591
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..20591
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..20591
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="5"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             637..1374
                     /locus_tag="ctg1_1409"
                     /transl_table=11
                     /translation="MKYNIILESFEGPLDLLYHLIEKEKVDIYDIPISKITDQYIAHIE
                     TMKELDLDVTSEFLVMAATLLEIKSKMLLPVSKKDEGFQQSMDELDPRVDLVRRLIEYK
                     KYKDASEKLKSREELYSKIYYKAKEEIEYEEEDIAFENIDLDHLIVVYKEILKKCIDYE
                     KEVEYKEIARDKVTIEESIDSILDMVNYRKKVFFEDLFQDKNTKAMVVVTFLALLELIK
                     QKLVSIKQEGNFARIVVELKNTK"
     PFAM_domain     694..1356
                     /aSDomain="SMC_ScpA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02616.16"
                     /description="Segregation and condensation protein ScpA"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1409_0088"
                     /evalue="6.60E-37"
                     /label="ctg1_1409"
                     /locus_tag="ctg1_1409"
                     /protein_end="240"
                     /protein_start="19"
                     /score="127.8"
                     /tool="antismash"
                     /translation="LIEKEKVDIYDIPISKITDQYIAHIETMKELDLDVTSEFLVMAAT
                     LLEIKSKMLLPVSKKDEGFQQSMDELDPRVDLVRRLIEYKKYKDASEKLKSREELYSKI
                     YYKAKEEIEYEEEDIAFENIDLDHLIVVYKEILKKCIDYEKEVEYKEIARDKVTIEESI
                     DSILDMVNYRKKVFFEDLFQDKNTKAMVVVTFLALLELIKQKLVSIKQEGNFARIVVE"
     CDS             1390..1929
                     /locus_tag="ctg1_1410"
                     /transl_table=11
                     /translation="MDKREIKSVIEGLLFTWGDPLSIKDIRDVLEIPEKEVNDILHEMI
                     DEFNYERRGIQILKTNNTYQLGTRAEHFEWMKKLCVPKESKTLSAAALETLSIIAYKQP
                     IIKSEIEAIRGVKCDKAISTLLEKKLIKEAGRLEKTGRPILYGTTDEFLKCFGLDTLKQ
                     LPQLKEIIEDKEEKNI"
     aSDomain        1405..1914
                     /aSDomain="TIGR00281"
                     /aSTool="tigrfam"
                     /description="TIGR00281: segregation and condensation
                     protein B"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1410_0023"
                     /evalue="9.70E-49"
                     /identifier="TIGR00281"
                     /label="ctg1_1410"
                     /locus_tag="ctg1_1410"
                     /protein_end="175"
                     /protein_start="5"
                     /score="163.5"
                     /tool="antismash"
                     /translation="IKSVIEGLLFTWGDPLSIKDIRDVLEIPEKEVNDILHEMIDEFNY
                     ERRGIQILKTNNTYQLGTRAEHFEWMKKLCVPKESKTLSAAALETLSIIAYKQPIIKSE
                     IEAIRGVKCDKAISTLLEKKLIKEAGRLEKTGRPILYGTTDEFLKCFGLDTLKQLPQLK
                     EIIEDKE"
     PFAM_domain     1414..1890
                     /aSDomain="SMC_ScpB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04079.18"
                     /description="Segregation and condensation complex subunit
                     ScpB"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1410_0089"
                     /evalue="1.80E-56"
                     /label="ctg1_1410"
                     /locus_tag="ctg1_1410"
                     /protein_end="167"
                     /protein_start="8"
                     /score="190.2"
                     /tool="antismash"
                     /translation="VIEGLLFTWGDPLSIKDIRDVLEIPEKEVNDILHEMIDEFNYERR
                     GIQILKTNNTYQLGTRAEHFEWMKKLCVPKESKTLSAAALETLSIIAYKQPIIKSEIEA
                     IRGVKCDKAISTLLEKKLIKEAGRLEKTGRPILYGTTDEFLKCFGLDTLKQLPQL"
     CDS             2011..2625
                     /locus_tag="ctg1_1411"
                     /transl_table=11
                     /translation="LKLIIFFILFIFIIIFAILLSTYKIKITIKIKDEHSYFSIRASTL
                     QGLLKHQYEVQFIDLILHENKPLLKTITARKEKDSYTKKEEKLNLNEIKNYINIIKKNK
                     EIYEEILNYILEKMIIEKFNLDIKVGLNDAATTAIIYGATNFLVGIPINVITRKKSFTE
                     MNINITPEFNKNILEVNFNCIIILRLVNIIIARRKAKPVNI"
     PFAM_domain     2389..2544
                     /aSDomain="DUF2953"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF11167.10"
                     /description="Protein of unknown function (DUF2953)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1411_0090"
                     /evalue="3.30E-11"
                     /label="ctg1_1411"
                     /locus_tag="ctg1_1411"
                     /protein_end="178"
                     /protein_start="126"
                     /score="43.2"
                     /tool="antismash"
                     /translation="IKVGLNDAATTAIIYGATNFLVGIPINVITRKKSFTEMNINITPE
                     FNKNILE"
     CDS             2653..3075
                     /locus_tag="ctg1_1412"
                     /transl_table=11
                     /translation="MGDHPIEGLMKTTMESIKGMIDVNTIVGSPVQTPDGQVIIPISKV
                     SFGFASGGGNYVVDKEGEEEIPFAGGSGAGVSVQPVAFMVVGNSKMKLLPVDQGNNMLN
                     SILDFIPKISNEMKKNDKSKKIMTMIYVKVIMKTKE"
     aSDomain        2659..3012
                     /aSDomain="TIGR02874"
                     /aSTool="tigrfam"
                     /description="spore_ytfJ: sporulation protein YtfJ"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1412_0024"
                     /evalue="2.90E-51"
                     /identifier="TIGR02874"
                     /label="ctg1_1412"
                     /locus_tag="ctg1_1412"
                     /protein_end="120"
                     /protein_start="2"
                     /score="171.0"
                     /tool="antismash"
                     /translation="DHPIEGLMKTTMESIKGMIDVNTIVGSPVQTPDGQVIIPISKVSF
                     GFASGGGNYVVDKEGEEEIPFAGGSGAGVSVQPVAFMVVGNSKMKLLPVDQGNNMLNSI
                     LDFIPKISNEMKKN"
     PFAM_domain     2743..2991
                     /aSDomain="Spore_YtfJ"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09579.12"
                     /description="Sporulation protein YtfJ (Spore_YtfJ)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1412_0091"
                     /evalue="1.60E-28"
                     /label="ctg1_1412"
                     /locus_tag="ctg1_1412"
                     /protein_end="113"
                     /protein_start="30"
                     /score="98.9"
                     /tool="antismash"
                     /translation="VQTPDGQVIIPISKVSFGFASGGGNYVVDKEGEEEIPFAGGSGAG
                     VSVQPVAFMVVGNSKMKLLPVDQGNNMLNSILDFIPKI"
     CDS             3134..4255
                     /locus_tag="ctg1_1413"
                     /transl_table=11
                     /translation="MKFKRLITIIIAIILFQSGIVTVYGTEDNSIKLSAKSAVLIDSAT
                     GRILYSNNGDKRLPMASTTKIMTALVAIEKGDLDKKVTIKKESVGIEGSSIYLAENEEI
                     SLRDLLYGLMLRSGNDAATAIANEIGGSTEEFSKMMNEKAKQIGAKNSNFMNPHGLHDE
                     NHYTTAYDLAIITKEALKSKEFREISKARTWIAEREINKHFYNKNNTLWEYEGGDGGKT
                     GFTKAAGRCLVTTATRNGTQLIAVVLNDGNWFNDCYTLMDYGFKNYKSFVIYSENQFIR
                     NIDVINGVKENISVITKDELIIPLKEEEKDKIKTVVKLPKELSAPINKGDKIGELQTFL
                     EGELISTTDLVSNDKVSEKSKYNKIKDMLKKII"
     PFAM_domain     3227..3883
                     /aSDomain="Peptidase_S11"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00768.22"
                     /description="D-alanyl-D-alanine carboxypeptidase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1413_0092"
                     /evalue="1.00E-68"
                     /label="ctg1_1413"
                     /locus_tag="ctg1_1413"
                     /protein_end="250"
                     /protein_start="31"
                     /score="231.5"
                     /tool="antismash"
                     /translation="KLSAKSAVLIDSATGRILYSNNGDKRLPMASTTKIMTALVAIEKG
                     DLDKKVTIKKESVGIEGSSIYLAENEEISLRDLLYGLMLRSGNDAATAIANEIGGSTEE
                     FSKMMNEKAKQIGAKNSNFMNPHGLHDENHYTTAYDLAIITKEALKSKEFREISKARTW
                     IAEREINKHFYNKNNTLWEYEGGDGGKTGFTKAAGRCLVTTATRNGTQLIAVVLND"
     PFAM_domain     3935..4204
                     /aSDomain="PBP5_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07943.15"
                     /description="Penicillin-binding protein 5, C-terminal
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1413_0093"
                     /evalue="3.50E-18"
                     /label="ctg1_1413"
                     /locus_tag="ctg1_1413"
                     /protein_end="357"
                     /protein_start="267"
                     /score="65.7"
                     /tool="antismash"
                     /translation="YKSFVIYSENQFIRNIDVINGVKENISVITKDELIIPLKEEEKDK
                     IKTVVKLPKELSAPINKGDKIGELQTFLEGELISTTDLVSNDKVS"
     CDS             4366..5334
                     /locus_tag="ctg1_1414"
                     /transl_table=11
                     /translation="LKHRLECIDAGSEYCPCYLAETNDCITCSHLQGKEFCECNWRGIC
                     IYQEYVMNGCKRKKQRESNVAKVEEIKNISDNCIILKLKVNNTLARQLKEPGAYVFLRG
                     EELPHYFDTPMSIMDVDEVNGYIYIAYQILGSKTKKLEKDREEYLVRGPYWNGLYGMKN
                     LKKVSNKECLVVVKGIAQAPAILVVKKLLKNQNNVTFIVDKGAIGDVFIKDFIKGLNMK
                     TIETNLQSSSGEMLIKNILKNNDIGLVYSGGSDVLHSSIIRMIDETKKDPFIVVTNNNE
                     ICCGEGVCGGCTIRLADGVRAKSCKTQLDARKVIERRVLND"
     CDS             5327..6121
                     /locus_tag="ctg1_1415"
                     /transl_table=11
                     /translation="MTKVIVIGGGWAGCAAALSAKKAGGDVTLIEKTDLLVGLGNVGGI
                     MRNNGRFTATEENILLGASELFNITDKVARHKNIKFPGHDHATLYDVTKVEPEVRRLLE
                     DRGIKVLLEARAMDVIMEDSKLKGIVLADETIVYGDVFIETTGSTGPIGNCLKYGNGCS
                     MCILRCPSYGPRASISSLAGIEDIVGKRGDECYGAFSGSCKLNKDSLSKEVIETLNREG
                     VVILKIPDEDINLEKLNIKVCQQYALKEFAQNVILLDTGHAL"
     PFAM_domain     5333..5977
                     /aSDomain="GIDA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01134.24"
                     /description="Glucose inhibited division protein A"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1415_0094"
                     /evalue="6.50E-27"
                     /label="ctg1_1415"
                     /locus_tag="ctg1_1415"
                     /protein_end="217"
                     /protein_start="2"
                     /score="94.7"
                     /tool="antismash"
                     /translation="KVIVIGGGWAGCAAALSAKKAGGDVTLIEKTDLLVGLGNVGGIMR
                     NNGRFTATEENILLGASELFNITDKVARHKNIKFPGHDHATLYDVTKVEPEVRRLLEDR
                     GIKVLLEARAMDVIMEDSKLKGIVLADETIVYGDVFIETTGSTGPIGNCLKYGNGCSMC
                     ILRCPSYGPRASISSLAGIEDIVGKRGDECYGAFSGSCKLNKDSLSKEVIET"
     CDS             complement(6116..7831)
                     /locus_tag="ctg1_1416"
                     /transl_table=11
                     /translation="LKRVAIYSRKSKFTGKGDSIENQIEMCKSFATRQLGEDLKFICYE
                     DEGFSGGNTDRPQFKKLMKDARNEEFDVLVCYRLDRISRNVADFSVLVEKLQSLKIDFI
                     SIREQFDTSTPMGRAMMYIASVFAQLERETIAERIKDNMIELAKNGRWTGGRIPLGFNS
                     EKVVYIDNKGSKKEKSLLIIDEKEMNFVKFLYEKYLELGSLHKLEIYMHENNIKSTNGI
                     IYEKSTLKIILQNPVYVKSSNKVIDYLLKNNWEIYGEPDGMHSLLTYNKTENISRGGKS
                     VKLVNTTGKRFAAVSKIKGALEPDLWLKVQEQFDINRDKFPRLGKTHNVLLTGKIRCGY
                     CDSYMTVQHGRVSKVTGEKVFYYVCSLKKKSRKKLCDNKNANASELDDLVIASLKKLAE
                     EKNEYICKLKSKNKEILTNSKSELEKVTIENTLKEKKLQIDNLVNKLSINTSIDEILMD
                     KIKSLKEECNGLSKKLKNIDSETKDIEMEQLDISFISSILNRCALIDKLSREEQKQLIN
                     ALIDTIYWYGDKKKIRIKFIGTSTDPDSNYGDFSTREYTIDELEQLNSELFFCS"
     PFAM_domain     complement(6650..6841)
                     /aSDomain="Zn_ribbon_recom"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13408.8"
                     /description="Recombinase zinc beta ribbon domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1416_0097"
                     /evalue="9.40E-14"
                     /label="ctg1_1416"
                     /locus_tag="ctg1_1416"
                     /protein_end="394"
                     /protein_start="330"
                     /score="51.8"
                     /tool="antismash"
                     /translation="LLTGKIRCGYCDSYMTVQHGRVSKVTGEKVFYYVCSLKKKSRKKL
                     CDNKNANASELDDLVIASL"
     PFAM_domain     complement(6887..7276)
                     /aSDomain="Recombinase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07508.15"
                     /description="Recombinase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1416_0096"
                     /evalue="1.10E-09"
                     /label="ctg1_1416"
                     /locus_tag="ctg1_1416"
                     /protein_end="315"
                     /protein_start="185"
                     /score="38.7"
                     /tool="antismash"
                     /translation="KEMNFVKFLYEKYLELGSLHKLEIYMHENNIKSTNGIIYEKSTLK
                     IILQNPVYVKSSNKVIDYLLKNNWEIYGEPDGMHSLLTYNKTENISRGGKSVKLVNTTG
                     KRFAAVSKIKGALEPDLWLKVQEQFD"
     PFAM_domain     complement(7376..7822)
                     /aSDomain="Resolvase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00239.23"
                     /description="Resolvase, N terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1416_0095"
                     /evalue="7.50E-40"
                     /label="ctg1_1416"
                     /locus_tag="ctg1_1416"
                     /protein_end="152"
                     /protein_start="3"
                     /score="136.4"
                     /tool="antismash"
                     /translation="VAIYSRKSKFTGKGDSIENQIEMCKSFATRQLGEDLKFICYEDEG
                     FSGGNTDRPQFKKLMKDARNEEFDVLVCYRLDRISRNVADFSVLVEKLQSLKIDFISIR
                     EQFDTSTPMGRAMMYIASVFAQLERETIAERIKDNMIELAKNGRW"
     CDS             8062..8154
                     /locus_tag="ctg1_1417"
                     /transl_table=11
                     /translation="MDKDKLIRKELRLIIGRLGLLNNNCLKLST"
     CDS             8680..9534
                     /locus_tag="ctg1_1418"
                     /transl_table=11
                     /translation="VDIMTLKEILIVGVPEVFIVILIGLVLGFSNDFFKQIRLWGLKLF
                     ISVMFILIGIYFIRSRATSIQSISIFCLITYIASYKFIFEMNTRKSIIIGSIVMFLILS
                     SEIVTFPVLKYIENGVYFKNRINVTIITRVIQIIILVLFYKANMHISNINMISCKWRDL
                     KIKEKITIVFIISLLVLCVIFNASYSDLYVKLNISNLKLEDSYIRLNMFMYFMENILFI
                     FIVLYLLNRTKNYYIFEEFLLQGDEAILRDLLELADEERIREYKKICDQYLEELDIPNR
                     VTE"
     CDS             9531..9671
                     /locus_tag="ctg1_1419"
                     /transl_table=11
                     /translation="MNKKFALKLIETTMRLIVSLFSMLAVQAQTCSAAFWKTKMSKALE
                     K"
     CDS             9717..10004
                     /locus_tag="ctg1_1420"
                     /transl_table=11
                     /translation="LKITELLNELGVDNFRDRAFLYKIISIFKGNNQCDNFVQTIINEF
                     ERDYSTIRKRMKRIIESNENNISNVLDIQKDKLTSKAFVQKLIKKTGAKK"
     CDS             10001..10591
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1421"
                     /sec_met_domain="AgrB (E-value: 5.1e-21, bitscore: 72.3,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNGIIKLFAYKIYKHTDKYNKDKHDKDEWREVLEYIVYRIMTFTL
                     LITMLVILSNLFTIDNDIYVFTISFLILKRKFGGMHLESEVGCFILSLIFPLIVYFLFK
                     NTHTQSEILIIMSITSAFMLAKIGTVDNVVRKLKKEHKLKLQKQGIIVLIIMLSINLYT
                     NNQFISLALIFTVINCLIGKIQYIKKIAGHEKK"
     PFAM_domain     10043..10537
                     /aSDomain="AgrB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04647.17"
                     /description="Accessory gene regulator B"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1421_0098"
                     /evalue="2.60E-20"
                     /label="ctg1_1421"
                     /locus_tag="ctg1_1421"
                     /protein_end="179"
                     /protein_start="14"
                     /score="72.7"
                     /tool="antismash"
                     /translation="HTDKYNKDKHDKDEWREVLEYIVYRIMTFTLLITMLVILSNLFTI
                     DNDIYVFTISFLILKRKFGGMHLESEVGCFILSLIFPLIVYFLFKNTHTQSEILIIMSI
                     TSAFMLAKIGTVDNVVRKLKKEHKLKLQKQGIIVLIIMLSINLYTNNQFISLALIFTVI
                     NC"
     CDS             11215..11376
                     /locus_tag="ctg1_1422"
                     /transl_table=11
                     /translation="MYKVELILPKDIQPLKERMTDVLTDIWIKKLGTKEKVDHLIKELE
                     KEDIEEFL"
     CDS             12154..12342
                     /locus_tag="ctg1_1423"
                     /transl_table=11
                     /translation="MTKMIMKIIRDVINTHKPLGLFWAKDTKANLYIAVNNNIGKAYKQ
                     KFKSLEECINWLMKEEV"
     CDS             12345..12587
                     /locus_tag="ctg1_1424"
                     /transl_table=11
                     /translation="MYTESVESLKKVELAINTLNDLEGDEAISGDEILNIIEPSTERLH
                     ELRIRLKLDINKCQEDRYSLKEDKADIFRKIAKGY"
     CDS             12590..12793
                     /locus_tag="ctg1_1425"
                     /transl_table=11
                     /translation="MKKLIKEWKYRLKNIDENLQIHIKAIENKEYTKDMRDYARSRVIS
                     LTEYKNLIESTIEALEKVKEEV"
     CDS             12797..13477
                     /locus_tag="ctg1_1426"
                     /transl_table=11
                     /translation="VNIRALRSDEIECRVQTVKQNGCSLLLFKDARCDMKILDETFGIM
                     GWQRKHELINNNLFCTISVWDKDKQMWISKQDVGVESYAEKEKGQASDSFKRACFNLGI
                     GRELYTAPFIWISLNSNEIIENKGKYNVKTKFRVKEISYNENKEIDRLVIVDNQGTVRY
                     ETGKHIKADNINRNTNSKSNTEKDKETDYKCLECGVDIIQAVNAYSNNKFGRALCRDCQ
                     NKQR"
     CDS             14211..14324
                     /locus_tag="ctg1_1427"
                     /transl_table=11
                     /translation="MDKDKIINHIGENFKKDALCVMAWNGIYAITYQAAIL"
     CDS             14267..14440
                     /locus_tag="ctg1_1428"
                     /transl_table=11
                     /translation="MCNGMEWDICNNLSSSYPLSSKNGSYEWEQKGKVNPVVEVICLHC
                     GFVAGISTLVMR"
     CDS             15440..16198
                     /locus_tag="ctg1_1429"
                     /transl_table=11
                     /translation="MNRDRLRRIWKKEENKVFKGWDFSYLDSRWYDEKLPWNYKKILKE
                     YLKSEYKILDMGTGGGEFLLSLNHPYNKTSVTEMWELNIKVCKEKLAPLGIGVYQIYQD
                     KILPFKDNSFDMIINRHESYDVKEIKRILRPRGIFITQQVGGRNNEILSNRLIKDFNPQ
                     FKNISLDNAIYELKENFFNIIYKNEYFPYLHFYDVGSIVYFAKIIEWEFPNFSVDSCFN
                     ELYDLYKELKQKSYVESFEHRFIIVCKNIK"
     PFAM_domain     15599..15859
                     /aSDomain="Methyltransf_11"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08241.14"
                     /description="Methyltransferase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1429_0099"
                     /evalue="4.80E-08"
                     /label="ctg1_1429"
                     /locus_tag="ctg1_1429"
                     /protein_end="140"
                     /protein_start="53"
                     /score="33.6"
                     /tool="antismash"
                     /translation="LDMGTGGGEFLLSLNHPYNKTSVTEMWELNIKVCKEKLAPLGIGV
                     YQIYQDKILPFKDNSFDMIINRHESYDVKEIKRILRPRGIFI"
     CDS             16493..16585
                     /locus_tag="ctg1_1430"
                     /transl_table=11
                     /translation="MDRKVIIMQCKGEEKRESVIPKCTILIGQY"
     CDS             17121..17606
                     /locus_tag="ctg1_1431"
                     /transl_table=11
                     /translation="MSSFYPLERLRKIRGLESARYEDPYSGGKANSVRYLSIAPRDNKM
                     KVAGLDNLLCGGEKAGLFVGHTEAITTGSLAGHNSVRLSLGMPLLELPRNLAVGDIIAY
                     ANESIGTKDGLKKRFTFAGSEFFERMKVTGLYTTNIEEIRKKIDGLNLLGIYEEKLV"
     PFAM_domain     17145..17378
                     /aSDomain="GIDA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01134.24"
                     /description="Glucose inhibited division protein A"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1431_0100"
                     /evalue="3.30E-09"
                     /label="ctg1_1431"
                     /locus_tag="ctg1_1431"
                     /protein_end="86"
                     /protein_start="8"
                     /score="36.4"
                     /tool="antismash"
                     /translation="RLRKIRGLESARYEDPYSGGKANSVRYLSIAPRDNKMKVAGLDNL
                     LCGGEKAGLFVGHTEAITTGSLAGHNSVRLSLG"
     PFAM_domain     17643..17756
                     /aSDomain="S4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01479.27"
                     /description="S4 domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1432_0101"
                     /evalue="2.90E-11"
                     /label="ctg1_1432"
                     /locus_tag="ctg1_1432"
                     /protein_end="38"
                     /protein_start="0"
                     /score="43.0"
                     /tool="antismash"
                     /translation="MRLQKFMAQCGVASRRKSEEIIQEGRVKVNGIIVKELG"
     CDS             17643..18350
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1154:Pseudouridine synthase (Score: 261.6; E-value:
                     7.2e-80)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1432"
                     /transl_table=11
                     /translation="MRLQKFMAQCGVASRRKSEEIIQEGRVKVNGIIVKELGVSIDSLE
                     DNITVDDKRIKPEGNKVYIALNKPTGYITTVSDQFGRKTVIDLISDIKERVYPIGRLDS
                     DTSGLLLLTNDGDLAYKITHPKHEISKKYIAKVKGIPKEHKLKQFREGLKIDDYITSKA
                     KVKIINEFEGNSILEIEIHEGKNRQVRKMCEKIGHEVIELERIAIGEINLKKIPLGKWR
                     FLEKKEIEYLKRQ"
     PFAM_domain     17829..18224
                     /aSDomain="PseudoU_synth_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00849.24"
                     /description="RNA pseudouridylate synthase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1432_0102"
                     /evalue="1.00E-21"
                     /label="ctg1_1432"
                     /locus_tag="ctg1_1432"
                     /protein_end="194"
                     /protein_start="62"
                     /score="77.8"
                     /tool="antismash"
                     /translation="YIALNKPTGYITTVSDQFGRKTVIDLISDIKERVYPIGRLDSDTS
                     GLLLLTNDGDLAYKITHPKHEISKKYIAKVKGIPKEHKLKQFREGLKIDDYITSKAKVK
                     IINEFEGNSILEIEIHEGKNRQVRKMCE"
     aSDomain        17841..18317
                     /aSDomain="TIGR00093"
                     /aSTool="tigrfam"
                     /description="TIGR00093: pseudouridine synthase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1432_0025"
                     /evalue="1.70E-53"
                     /identifier="TIGR00093"
                     /label="ctg1_1432"
                     /locus_tag="ctg1_1432"
                     /protein_end="225"
                     /protein_start="66"
                     /score="178.6"
                     /tool="antismash"
                     /translation="NKPTGYITTVSDQFGRKTVIDLISDIKERVYPIGRLDSDTSGLLL
                     LTNDGDLAYKITHPKHEISKKYIAKVKGIPKEHKLKQFREGLKIDDYITSKAKVKIINE
                     FEGNSILEIEIHEGKNRQVRKMCEKIGHEVIELERIAIGEINLKKIPLGKWRFLE"
     CDS             18484..18915
                     /locus_tag="ctg1_1433"
                     /transl_table=11
                     /translation="MIIARKINSEKEEEVLKNILRQYNINDEHKDNDVTYILLLDDKIV
                     GVCKLTCYHDIGILKYIVIDKKETGQDLGDALLRSALNYCFRNNISRVYYKTIDDYLIK
                     KGFEKNKNYLKNVEHEEEYLLEVNLERFFNRPCKSSGGR"
     PFAM_domain     18550..18774
                     /aSDomain="Acetyltransf_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00583.27"
                     /description="Acetyltransferase (GNAT) family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1433_0103"
                     /evalue="5.20E-06"
                     /label="ctg1_1433"
                     /locus_tag="ctg1_1433"
                     /protein_end="97"
                     /protein_start="22"
                     /score="26.8"
                     /tool="antismash"
                     /translation="YNINDEHKDNDVTYILLLDDKIVGVCKLTCYHDIGILKYIVIDKK
                     ETGQDLGDALLRSALNYCFRNNISRVYYKT"
     CDS             18919..19509
                     /locus_tag="ctg1_1434"
                     /transl_table=11
                     /translation="LYKHLNSIISIAKEIIDRTVKKGSIVVDATVGNGQDTIKLAELVG
                     ETGKVYGFDIQSIAIKNTKKRLIQENLENRVELINDGHEKIDCYISKEVDFIIFNLGYL
                     PGGDHTIVTRKDSTLEAIKKSLVILKPNGIMLLAVYHGHYEGKVEKRYIDELLKELSQK
                     KFNTLKFEFINQINNPPILYAIEKNMSFLKEMR"
     PFAM_domain     19066..19476
                     /aSDomain="rRNA_methylase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06962.14"
                     /description="Putative rRNA methylase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1434_0104"
                     /evalue="3.10E-51"
                     /label="ctg1_1434"
                     /locus_tag="ctg1_1434"
                     /protein_end="186"
                     /protein_start="49"
                     /score="173.0"
                     /tool="antismash"
                     /translation="VYGFDIQSIAIKNTKKRLIQENLENRVELINDGHEKIDCYISKEV
                     DFIIFNLGYLPGGDHTIVTRKDSTLEAIKKSLVILKPNGIMLLAVYHGHYEGKVEKRYI
                     DELLKELSQKKFNTLKFEFINQINNPPILYAIE"
     CDS             19509..20375
                     /locus_tag="ctg1_1435"
                     /transl_table=11
                     /translation="MEEKIDLINLIKEKFEDLSKGQKLIANYIISNYDKAAFMTAARLG
                     QVVGISESTVVRFANTMGYDGYPNLQSELQELIKSKLTTVQRLSMSQDDYSNKNIGVRK
                     ILKTDMENIRHTIDDIDTEIFEEVVNSILKAKKVYILGLRSSNALSSYLGFYLGVILDD
                     VKVVNLGISDIFEQLIRVTKDDVVIGISYPRYSRRTLDALKYVRDQGCKVIGITDSEAS
                     PITSIAHLTLFARNNMVSFVDSLVAPMSLINALIVSIGMRVKNEVAEYFQELENIWEEY
                     NIYDRKL"
     PFAM_domain     19527..19742
                     /aSDomain="HTH_6"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01418.19"
                     /description="Helix-turn-helix domain, rpiR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1435_0105"
                     /evalue="1.30E-13"
                     /label="ctg1_1435"
                     /locus_tag="ctg1_1435"
                     /protein_end="78"
                     /protein_start="6"
                     /score="50.8"
                     /tool="antismash"
                     /translation="LINLIKEKFEDLSKGQKLIANYIISNYDKAAFMTAARLGQVVGIS
                     ESTVVRFANTMGYDGYPNLQSELQELI"
     PFAM_domain     19902..20279
                     /aSDomain="SIS"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01380.24"
                     /description="SIS domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1435_0106"
                     /evalue="5.10E-22"
                     /label="ctg1_1435"
                     /locus_tag="ctg1_1435"
                     /protein_end="257"
                     /protein_start="131"
                     /score="78.2"
                     /tool="antismash"
                     /translation="ILKAKKVYILGLRSSNALSSYLGFYLGVILDDVKVVNLGISDIFE
                     QLIRVTKDDVVIGISYPRYSRRTLDALKYVRDQGCKVIGITDSEASPITSIAHLTLFAR
                     NNMVSFVDSLVAPMSLINALIV"
ORIGIN
        1 gataatagct aaatcaattg ccttaccagg gctacttatt gccatcatat ttcatgaact
       61 tgctcatgga tattctgcat atcttctagg agattctaca gctaaaaatt atgggagact
      121 tactttaaat ccaatatcac atatagatcc tttaggcttt ataatgttgt atgtaattgg
      181 atttggatgg gcaaaaccag ttccaataaa tccaaataat tttaaaaata gaaaaagaga
      241 taatataatt gtttcattag ctggatcttt tacaaatttt attatagtaa ttattactat
      301 aatagtgctt gtaataagtg ttaagttaaa agcaaatgat attttcataa gcattgtgta
      361 tataattatg caatacaatc tatcatttgg aatattcaac ttacttccat ttcctccgct
      421 agatggctct aaagttgtag caagtttact acctttgaaa tatgaaatta agttttatca
      481 atatgaaaga tacctatatg cagctttaat tgttttatta ataactaata gaattgataa
      541 aatactagga aaattattat ttataggcaa tagccttata atggatatga taaatatgtt
      601 aattagatta atataaatat aaaataggag aaaaaaatga agtataatat tatattagaa
      661 tcttttgaag gcccactaga cttactttat catcttatag aaaaagaaaa agttgatata
      721 tatgatatac ctatatctaa gataacagat caatatatag ctcatataga aactatgaaa
      781 gaactagatc tagacgttac tagtgaattt ttagtgatgg ctgctacact attggaaatt
      841 aaatcaaaaa tgcttttacc tgtatctaag aaagatgaag gttttcagca atctatggac
      901 gagttagatc cgagggttga tttagtgaga agacttatag agtacaaaaa gtataaagat
      961 gcttctgaaa aactaaaatc tagagaagaa ttatatagta agatttatta taaagcaaaa
     1021 gaagaaatag aatatgaaga agaggatatt gcgttcgaaa atatagactt agaccactta
     1081 atagttgtgt ataaagaaat attaaaaaag tgtattgatt atgaaaaaga ggtagaatat
     1141 aaagaaatag caagagataa agtaacaata gaggaaagta ttgatagtat cttagatatg
     1201 gttaactata gaaaaaaagt gttttttgaa gatttatttc aagataaaaa tacgaaagca
     1261 atggttgtag tgacattttt agctttacta gaacttataa agcaaaaact tgtatctatt
     1321 aaacaagaag ggaattttgc aagaatagta gtagaattaa aaaatacaaa ataaaactag
     1381 gagtgcctta tggataagag agagataaaa tctgtaattg aagggttatt atttacatgg
     1441 ggtgaccctt tatcgattaa agacattagg gacgttttgg aaatccctga aaaggaagtt
     1501 aatgatatac tgcatgaaat gatagatgag tttaattatg aaagaagagg tatacaaata
     1561 ctaaaaacta ataatacata tcagttaggt acaagagcag aacactttga atggatgaaa
     1621 aaactttgcg taccaaagga aagtaaaaca ctttctgctg ctgcactgga gacactatct
     1681 attatagctt ataaacaacc gataattaag agtgagatag aagctataag aggtgtaaag
     1741 tgtgataagg caatatcaac tttattagaa aagaagttaa taaaagaagc tggtagatta
     1801 gagaaaacag gaagacccat attgtatggt actacagatg agtttttaaa gtgttttgga
     1861 ctagatacat tgaaacaatt acctcagtta aaagaaataa ttgaagataa agaagagaag
     1921 aatatttaaa taacacaagt ttttgtgtta tttttttttt attgggaaaa ataactttta
     1981 aactgtatat atagaatggg gtgaattaga ttgaaattaa ttatattttt tatacttttt
     2041 atatttataa ttatattcgc tatattgtta agtacttata aaataaagat tactataaaa
     2101 ataaaggatg aacatagcta ctttagcata agagcttcta cgcttcaagg attattaaag
     2161 caccaatatg aagttcaatt tatagattta attttacatg aaaataaacc tcttttaaag
     2221 acaatcacag ctcggaaaga aaaagattca tatacaaaaa aagaagagaa gttaaattta
     2281 aatgaaataa aaaattatat aaatattatt aaaaaaaata aggaaatata tgaagaaata
     2341 ttaaattaca tattggaaaa aatgataata gagaaattta atctagatat taaggttgga
     2401 ttaaatgatg ctgctacaac tgcgataatt tatggagcta ctaattttct agttggaata
     2461 cccataaacg ttataactag aaaaaaaagt tttacagaaa tgaatataaa tattactcca
     2521 gaatttaata agaatatttt agaagtaaat tttaactgta taattatcct gagattagta
     2581 aatattatta ttgcaagacg taaagcgaaa cctgtaaaca tttagttaca aatttaaaag
     2641 gtggtgaagt aaatgggaga tcatcctata gagggactaa tgaaaactac tatggaaagc
     2701 attaagggca tgatagatgt aaacacgatt gtaggaagcc ctgtacagac tccggatggc
     2761 caggtaataa tacctatatc taaagtttct tttggatttg catctggtgg tggaaattat
     2821 gttgtggata aagaaggaga agaggaaatt ccttttgctg gtgggtcagg agctggagta
     2881 tcagttcaac cagtagcttt catggtggtt ggaaacagta agatgaagct attacctgta
     2941 gatcaaggaa ataatatgct aaatagtata ttagacttta ttcctaaaat atcaaatgaa
     3001 atgaaaaaaa atgataaaag taaaaaaata atgacaatga tatatgtgaa agtgattatg
     3061 aaaactaaag agtaaacaac tgctctttag tttttcaata caaaactaca cttggactat
     3121 ttggagtgat aatatgaagt ttaaaagact aattaccatt attatagcta taatattatt
     3181 tcaaagtggt atagttactg tatatggtac agaagataat agtataaaat tatcagcaaa
     3241 aagtgctgtt ttaatagatt ctgctacagg tagaatattg tattcaaaca atggtgataa
     3301 acgactccca atggctagta ctactaaaat aatgactgca cttgtagcaa ttgagaaagg
     3361 cgatttagat aaaaaagtaa ctattaaaaa ggaatctgtt ggaatagaag gatcaagtat
     3421 atatttagct gagaatgaag aaatctcact aagagattta ctatatggcc ttatgcttag
     3481 atcaggaaat gatgcggcta cggctatagc taatgaaata ggaggttcaa ctgaagaatt
     3541 ctctaaaatg atgaatgaaa aagctaaaca gattggagct aaaaatagta actttatgaa
     3601 tccacatggt ttgcatgatg aaaatcatta taccacagct tatgatctgg ctattataac
     3661 caaagaggct cttaaaagta aagaatttag agaaatatca aaagctagaa catggattgc
     3721 agagagagaa ataaataaac atttttataa taaaaataat acactatggg agtatgaagg
     3781 tggagatgga ggaaagacag gctttacaaa ggctgcagga agatgtcttg tcacaactgc
     3841 aactagaaat ggtacacaac taatagctgt agtacttaat gatggaaact ggtttaatga
     3901 ctgctatact ttaatggatt atggttttaa aaactataaa tcttttgtaa tctatagtga
     3961 aaatcaattc ataaggaata tagatgtaat aaatggagtt aaagaaaata tatcagtaat
     4021 tacaaaagat gagttaataa ttccactgaa agaggaagaa aaggataaaa taaaaacagt
     4081 tgtgaaatta cctaaggaat taagtgcacc tattaacaaa ggggataaaa ttggtgaatt
     4141 acaaacattt ctagaaggag agttaatatc tactacagat ttagtatcta atgataaggt
     4201 aagtgaaaaa agtaaatata ataaaataaa agatatgctt aagaaaataa tatagtataa
     4261 aggtttgatt taataaaatc agacctttat attttttgta acaaaatatg aattataaaa
     4321 taatctatat attataatat tatattttga gaggaggata aatctttgaa acatagacta
     4381 gaatgcattg atgcaggaag tgaatattgt ccttgttact tagctgaaac aaatgattgt
     4441 ataacgtgct cacacttaca aggaaaggaa ttttgtgagt gtaattggag gggaatatgc
     4501 atatatcagg aatatgttat gaatggttgt aagaggaaaa agcaaaggga gtctaatgtt
     4561 gctaaagtag aggagataaa aaatataagt gacaattgca ttatattaaa acttaaagta
     4621 aataacacat tagcaagaca attgaaggaa cctggtgctt atgttttttt aagaggagaa
     4681 gagttaccac attatttcga tactccaatg tctataatgg atgtagatga agtaaatgga
     4741 tatatatata tagcgtatca aatattggga tctaaaacaa agaaacttga gaaggataga
     4801 gaagagtatc tagttagagg accttactgg aatggattat atggaatgaa aaacttaaag
     4861 aaagtatcaa acaaggaatg tcttgtagta gtaaaaggaa ttgcacaagc accagcaata
     4921 ctggtagtaa agaaattact taagaaccaa aataatgtga cgtttatcgt ggataaagga
     4981 gctataggag atgtgtttat aaaggatttt ataaaaggtt taaatatgaa aactatagaa
     5041 acaaatctcc agagtagtag tggtgaaatg ttaattaaga atatcctaaa aaataatgat
     5101 ataggattag tttatagtgg cggatctgat gtacttcaca gttcaataat aagaatgatt
     5161 gatgaaacta aaaaagatcc atttatagta gttactaata ataatgaaat ttgttgcggg
     5221 gaaggagttt gcggtggatg tactataagg ctagcagatg gagtaagagc aaaatcttgt
     5281 aaaacgcaat tagatgcaag aaaagtaata gagaggagag ttcttaatga ctaaagttat
     5341 agttattgga ggaggatggg ccggatgtgc agctgcacta agtgctaaaa aagctggtgg
     5401 tgatgtcaca ttaatagaaa aaacagatct tttagtagga ctaggtaatg taggcggtat
     5461 aatgagaaat aatggtagat ttactgctac agaagaaaat attttactgg gtgcttctga
     5521 actattcaat ataacagata aagtagctag acataaaaat ataaaatttc cgggacatga
     5581 tcatgccaca ctatatgatg ttactaaagt agaacccgag gtaagaagat tgttagaaga
     5641 cagaggtata aaagtgcttc ttgaagccag agctatggac gttataatgg aagatagtaa
     5701 attaaaaggt atagtattag cagatgaaac tatagtatat ggtgatgtat ttatagaaac
     5761 tactggatcc acggggccaa taggtaactg tttaaaatat ggaaatggtt gctccatgtg
     5821 catattaaga tgtccttcat atgggccaag agcaagtatt agtagtttag ctggaattga
     5881 agatatagtt ggaaaaagag gagatgaatg ctatggtgcg tttagtggat cttgcaagtt
     5941 aaataaagat tcattaagta aagaggttat tgagacctta aatagggaag gcgtagtgat
     6001 actaaaaatt ccagatgagg atataaactt agaaaaactt aatattaagg tttgtcagca
     6061 atatgcatta aaggaattcg cacagaatgt gatcttacta gatactggtc atgcactatg
     6121 aacaaaagaa caactctgaa ttgagttgct ccagttcatc aattgtatac tcccttgtgg
     6181 aaaaatcacc ataattgcta tcaggatccg tactagtacc tataaattta attcttattt
     6241 ttttcttatc accgtaccaa tatatagtgt ctattaaagc atttattagt tgtttttgtt
     6301 cttctctaga aagtttatca attaaagcac atctatttaa tatacttgaa ataaaactaa
     6361 tatctaattg ttccatttct atatcttttg tttcactatc tatatttttt aatttcttgc
     6421 taaggccatt acattcttct tttaatgatt ttattttatc cataagtatc tcatctatac
     6481 tagtatttat agagagctta ttaactaaat tatctatctg aagtttcttt tccttcaaag
     6541 tattttcgat tgtgactttt tctaattcac ttttactatt agttaggatt tctttatttt
     6601 tagatttcaa tttacatatg tattcattct tttcttcggc aagtttttta aggctagcta
     6661 taactaaatc atctaactct gaagcattag cattcttatt atcacatagc ttttttcgag
     6721 attttttttt aagagagcat acatagtaaa atactttttc acctgtaacc ttagacactc
     6781 ttccatgctg aacagtcata taactgtcac aatagccaca tcgtatttta cctgttaaaa
     6841 gtacattgtg agtttttccg agtcgtggaa acttatctct atttatatca aactgttctt
     6901 gcacttttaa ccatagatcg ggttctaaag ctccctttat tttgctgacg gccgcaaatc
     6961 ttttgccagt agtgtttact aacttaacac ttttaccacc tctactaata ttttcagttt
     7021 tattgtaggt tagtagtgag tgcataccat caggctctcc atatatttcc caattatttt
     7081 tcaataggta gtcaattact ttattactag atttcacata tacaggattt tgaagaatta
     7141 tttttaatgt agatttctca tatattatac catttgttga ttttatattg ttttcatgca
     7201 tatagatttc aagtttatgt aaactaccta actctaagta tttttcatat aggaacttaa
     7261 caaaattcat ttctttttca tctataatta aaagagattt ttctttttta gatcctttgt
     7321 tatctatata tactactttt tcagaattaa atcctaatgg tattctacca cctgtccatc
     7381 ttccattctt agcaagctca atcatattgt cttttatgcg ttcagcaata gtctctcttt
     7441 ctaactgtgc aaatacacta gcgatataca tcatagctct tcccataggt gtagaggtat
     7501 cgaactgctc ccttatagaa ataaaatcta ttttaagaga ttgcaatttt tcaactagga
     7561 cagaaaagtc agcaacattc ctacttattc tatctaatct atagcacact agaacatcaa
     7621 actcttcatt tctagcgtct ttcattaatt ttttaaactg aggtctatca gtattcccac
     7681 cagagaatcc ttcatcttca taacatataa atttaagatc ttcacctaac tgtctagtag
     7741 caaagctttt acacatttca atttgatttt caatactatc tccttttcct gtaaacttag
     7801 atttacggga gtatatagca actcttttca aattttcatc tcctttgctt tttagtgttt
     7861 aaattagtac atattataat atatattttt aattgctgac tttatgaact aattacttta
     7921 ttatattact gtttataaat atattagagt gtaaactcta ataccaactg aagtatggga
     7981 aaataacgtt tttatatatt gaaatatgtg cctcgatata gtatggttaa gcgataatgt
     8041 tgattaaatg aggcgataaa aatggataaa gataaattaa ttagaaaaga gctaagacta
     8101 attataggaa gattaggatt gcttaataat aattgtctaa aattaagcac ttgataattt
     8161 gatactagat tatgtatatc tttatctcta atttgattaa cttcactata taatttctat
     8221 ctatcaatta taatatattc agatttgatc catataaatg ataagttaaa gtctgagcag
     8281 atctgatgct attagaaatt atatgacttt tttataaatt attgttggta actataaaag
     8341 ttatcattaa tagtttattc tctaggtgtt gaactatagt tattaatatt agcatctatg
     8401 tctttacatt ttgcgatatc agaaatagaa gttagtacta atataaatat taaaacagtt
     8461 gatacaaatt ttctttttat ctacaatcat tataaaaaca ataagctcaa atattttcta
     8521 aaaagcatgt atctatcgca aaatttgaca tttatttaaa tgtgtaaaat tagcaatcaa
     8581 tcaaatgatt ttacaattcc tgtcggaaga tgtcgacaaa agccctactt ctctaatata
     8641 acaataagtg ttaagattaa tataagaggt gatgtatttg tggatattat gactcttaag
     8701 gaaatattaa tagtaggtgt accagaagta tttattgtaa ttttaatagg attagtactt
     8761 ggatttagta atgatttttt taaacagata agactatggg gtttaaaact tttcatatca
     8821 gtaatgttta ttttaatagg tatatatttt attaggagta gagcaacaag tattcaaagt
     8881 ataagtatat tttgtcttat tacatatata gcaagttata agtttatatt cgagatgaac
     8941 actagaaaaa gtataataat tggaagtata gttatgtttc taatactttc atcagaaata
     9001 gttacatttc cagttttaaa gtatatagaa aatggagtct attttaagaa tagaattaat
     9061 gtaactatta taactagagt tattcagatt attattttag tattgtttta taaagctaat
     9121 atgcacataa gtaatataaa tatgatctcg tgtaaatgga gagatcttaa gattaaagaa
     9181 aaaataacta ttgtatttat aatatcttta ttagtattat gcgtaatatt taatgctagc
     9241 tattcagact tatatgtaaa gttaaatatt agtaatttaa aacttgaaga tagctatata
     9301 agattaaaca tgtttatgta ttttatggaa aatatacttt ttatattcat agtattgtat
     9361 cttcttaaca gaacaaaaaa ctattatatt tttgaggaat ttttattaca gggagatgaa
     9421 gcaatccttc gtgacttatt agaattagca gatgaggaga gaattaggga gtataaaaaa
     9481 atctgtgatc aatatcttga agaattagat atacctaata gggtgactga atgaataaaa
     9541 agtttgctct taaactaata gaaactacta tgaggttaat agtttcttta ttttcaatgt
     9601 tagccgtaca agctcaaaca tgctctgcag cattttggaa aactaaaatg tcaaaagcac
     9661 tagaaaaata agaacaggag cttcctcctg ttcttattta aagaggaggg agttagttga
     9721 aaataactga attacttaat gagcttggag tagataactt cagggataga gcatttctgt
     9781 ataaaataat atctatattt aaaggaaata atcagtgtga taatttcgtt caaactatta
     9841 taaatgaatt tgaaagagac tattctacta taagaaagag aatgaagaga attatagaaa
     9901 gtaatgaaaa taatatatca aatgtactag atatacaaaa ggataaatta acaagtaagg
     9961 cttttgtaca aaagctaatt aaaaaaacag gagcaaagaa atgaatggaa ttattaaact
    10021 atttgcatat aaaatatata aacataccga taaatataac aaagataaac atgataaaga
    10081 cgaatggaga gaagtgttag aatatatagt ttatagaatc atgacattta ctctacttat
    10141 aacaatgcta gttatattat caaatctatt tacaatagat aatgatatat atgtatttac
    10201 tattagcttt ttaattttaa aaagaaagtt tggtggaatg catctagaaa gtgaagtggg
    10261 atgttttata ttaagtctaa tatttccact catcgtatat ttcttattta aaaatactca
    10321 tacccaaagc gaaattctta taattatgag cattacttct gctttcatgc tggctaaaat
    10381 aggaacggta gataatgtag tgagaaagct aaagaaagaa cataaattaa agttacaaaa
    10441 acaggggatt atagtcctaa taataatgtt atcaataaat ttatatacaa ataatcagtt
    10501 tatatcttta gcgctaattt ttacagtaat aaactgctta attggtaaaa ttcaatatat
    10561 taaaaaaatt gcaggacatg agaaaaaata atataataaa gctcacaaac aaatattcct
    10621 tttatgctgt agacttatta gtataagaca aggaggaata tagtaatgat aaaatatata
    10681 ctttggtatg gtaattatat agataaatat ggctgcgata tataagctta gattataaag
    10741 ctagttaaac aaaagagagg taaaatctat taatagattt tacctctctt ttgtttaact
    10801 aaggatatgt tgaattttgt attttttaaa agaattctca aagcgtttat atatttagta
    10861 attttacata ttacactgta ataatttaaa tacagataaa ttttatcatt tcttaaatga
    10921 agtcatttag atttatttta atagattcta aactagatat ttctatgttc ctaatctttt
    10981 agttatctat atattagtgt tagaatattg gaaagtaaca ctatggaaaa agttaagata
    11041 aaactatcct ataaatataa gctcataaaa agaagtaagt gcaggctaag ctataaggta
    11101 gtgaagaagt atatttactt caaattagtt aattattaac ttagctttaa actagctaat
    11161 agactgtcat aggacattca gtggtacaca tagcatttag taaggaggtt gaaaatgtat
    11221 aaagttgaac tgattttgcc taaagatatt caaccattaa aagaaagaat gactgatgta
    11281 ctcacagata tatggataaa gaagttaggt acaaaagaga aagtagatca tcttataaaa
    11341 gaattagaga aagaagatat agaagaattt ctttaaaaaa gacgtaagat aaacacaaca
    11401 ttagacttta aaaattattt gtatatagtt gctttttaca gtattaaagg attaatctta
    11461 aattttaaga aaaggacaaa atataacgaa aggtagtgca ttaataaacc ttcgctataa
    11521 aaatagaatt aaataacgtg tgctgctata gaatatacaa ttagatctta tgatttacac
    11581 taaaatacgg ttgaaaataa taataacata ataagaagat cttaaatgtt taatataatt
    11641 atttaactat tagaatcgag gaataatact atgagactct acagtttata agatagagct
    11701 atagatataa tagttatcag tatatataat gacaaacaca agaaacaata gaactaaaag
    11761 tgaagattat agctttattg gccaataaat taaaaagaaa aaggttcttc agatctgaca
    11821 ctctgaagaa cttaaacttg atagcttaaa aatatgttta atataagcgt tatactacat
    11881 agaaatgagc tttatgaaga gaaataattc aataatttaa atctcttaga actattataa
    11941 aagttatcaa tatctccttt aagaacaaag tgtaaagaaa aaatacaaaa gaatatacat
    12001 gctttaaaga atcattattt aaatctttaa aaaataacga tagcataaaa attttaaaaa
    12061 aatagtgatt ggataaagga tacataaaag aagaaaaaga gattttaaat agatcacaaa
    12121 aaactagaga acaagttata gctttaggaa tgaatgacga aaatgattat gaaaattata
    12181 agagatgtta taaatactca taaaccttta ggtctgtttt gggcaaaaga taccaaggct
    12241 aatttatata tagcagtaaa taataatata gggaaagctt ataaacaaaa gttcaaatca
    12301 ctagaagaat gcataaattg gttaatgaag gaggaagtat agtgatgtat acagagtcag
    12361 tagaatcact aaaaaaagta gagttagcca taaatacttt aaatgattta gaaggtgatg
    12421 aagcaattag tggtgatgag attttaaata taatagagcc ttcaactgaa cgcttacatg
    12481 aacttagaat aagattaaaa ttagatatta ataagtgtca agaggacagg tattcactaa
    12541 aagaagataa agcagatatc ttcagaaaga tagcaaaagg atattaaaca tgaaaaagct
    12601 tataaaggaa tggaaataca gacttaaaaa tatagatgaa aacttacaga tacacataaa
    12661 agcaattgag aataaagaat atacaaaaga catgagagac tatgcaagaa gtagagtgat
    12721 tagtttaaca gaatataaga atcttataga aagtacaata gaagcacttg agaaagtgaa
    12781 agaggaggta tagaaagtga atatcagggc attaaggtct gatgaaatag aatgtagagt
    12841 acaaacagta aagcaaaatg gatgttcttt gcttctgttt aaagatgcaa gatgtgatat
    12901 gaaaatacta gatgaaacct ttggaataat gggatggcaa agaaagcatg agcttataaa
    12961 taataacctg ttttgtacta tatcagtttg ggataaagat aaacaaatgt ggattagtaa
    13021 acaagatgtt ggagttgaaa gctatgcaga aaaagaaaaa gggcaagcat cagatagctt
    13081 taaaagagca tgttttaact taggtatagg tagagaactt tatacagctc cttttatatg
    13141 gattagttta aatagtaatg agataattga gaataaagga aagtataatg tcaaaacaaa
    13201 gtttagagtt aaagaaataa gttataacga aaacaaagag atagatagac tagttatagt
    13261 tgataaccaa ggaacagtaa gatatgagac aggaaagcat ataaaagcag acaatattaa
    13321 tcgcaatacg aacagtaaaa gcaacactga aaaagataaa gaaacagact ataagtgctt
    13381 agaatgtgga gtagatatta tacaagcagt aaatgcatat agcaataata aatttggacg
    13441 agcattgtgt agagattgtc aaaataagca aaggtagatg agattatgag gagatacagc
    13501 tatgaagaat atctacgaat atgttattgg aatgacgaag aaccaatgac tgagaaagag
    13561 tatgcagagt ttttagaaac taattatgac taagtaaata taggggtctc tacaataaga
    13621 gatccctaat aaaaagatat ataaatatca tgcttgttat aattgttcta ttactaagaa
    13681 taatgaaagt ctgtgctgaa aatcatgtta tgggaaaccc aaaatacaaa aagaaaataa
    13741 tattgatttt gaaaatattt caatcaatac aaagaacttt taaattatat gatattacaa
    13801 ataaacatta tatcttataa cgaatctggc ttgaataaag aatactccct agcttcaacg
    13861 ctttaagttt tacattcact tatagtgata gaaaacaaag attttctaaa aaaatataat
    13921 aatgaaaata cctcattgat aaagagaaaa cttaagcagt aaagacataa acagtcgcta
    13981 aaaacaagat ttttcaagaa atggaggtaa aagagaaaga gtttagaaaa aatcataaaa
    14041 gacttaagtc tatattggga tttcatgaag atttaactaa agctagagta attttaagaa
    14101 caagttcata tgtgaaaatt tgaaatagta aatatttagg atggtatcag agaaataaag
    14161 gaatattatc ttttacatag aaatttatat gtaaagggga gtgatagtag atggataaag
    14221 ataaaattat aaatcatata ggtgaaaatt ttaaaaagga tgccctatgt gtaatggcat
    14281 ggaatgggat atatgcaata acttatcaag cagctatcct ttaagcagta aaaacggtag
    14341 ttatgagtgg gaacaaaaag gaaaggtaaa tcctgtagta gaagttatat gcttacattg
    14401 tggatttgta gcgggaatat ctactttagt aatgagatag agactaagag cctacttgtt
    14461 gttcttttaa tcttaaaaaa taattaaaat atttgagtaa atatagaatc ataaataatt
    14521 gaacaaatta taaagttaaa ttaaatatct atgttaattg ctgaaatggc ggaaatataa
    14581 taaaaaataa ataattttaa acataataac aaagaaaaag ataagtggct gatagcttag
    14641 agacaacaaa atcactttta atagaccttt aaagggctag tatatgacaa tagagaggat
    14701 caataacttt acattaaggc tagaaaacgg aaatataaaa aattatttta aagatgtcca
    14761 aaagcaccat agacaaaata ttgacatgct agcaagttat attcgcaacc gaaagagaag
    14821 atagaaatta aaggagaaat atatctgaaa aggttttgga gaggtaatcc ggattataaa
    14881 tcaagagatc ttgtatgtga aatattacaa aatgatagga aatctaccga gaagttaaaa
    14941 aggttaactt aatttaaaaa agggtctaag cagcaaaggc tcttttttat gtaataaggc
    15001 aattttaata tgtatacgag cataacgtaa gtgttataca atgataaaaa tgattattct
    15061 ttttactcca caaaaataat atttgttaaa atgatattta gagagactta atttctttat
    15121 atggcttata tgctatatat aatatcttta tcttaatatc ctaagatcta cttattgttg
    15181 aatttcaata tttacaaata ctacatacga cttccagtaa atgtttgata taatgaatta
    15241 agataaatat tataatttta ctatctatga agtttaatta tataaaagta gatgaattct
    15301 tatgagaata aaacgaatta attactcggt gcagtttata taaatgatag tatattgtac
    15361 cgagaaaaga aaaatattac tatcagcgta actgcatcgt cctttttagt atccagataa
    15421 tattagggag gaaagggtta tgaatcgtga tagacttaga agaatatgga agaaggaaga
    15481 gaataaggtt tttaaaggat gggatttttc ttatttagac agcagatggt atgatgaaaa
    15541 gctaccttgg aactataaaa aaatattaaa agagtattta aaatcagaat ataaaatact
    15601 tgatatggga acaggtggag gagaattctt attatcttta aatcatccat ataataaaac
    15661 ttcagttaca gagatgtggg aacttaatat aaaagtatgt aaggaaaaac tagctccgct
    15721 aggtattggt gtgtaccaaa tataccaaga taaaatctta ccttttaaag ataattcttt
    15781 tgacatgatt ataaatagac atgaatcgta tgatgtaaaa gaaataaaga gaatattaag
    15841 gcctagaggt atatttatta ctcaacaagt tggtgggaga aataatgaaa ttctttcgaa
    15901 tcggttaata aaagatttta acccgcaatt taagaacatt agcttagata atgctatata
    15961 cgaattaaaa gaaaacttct ttaacatcat atataagaat gagtattttc catacttaca
    16021 tttttatgat gttggttcta ttgtatactt tgcaaaaatc atagagtggg agtttccaaa
    16081 cttttcggta gatagttgct ttaatgaact atatgactta tataaagaac taaaacaaaa
    16141 gtcatatgta gaaagttttg aacacagatt tattatagta tgtaaaaata taaaatagct
    16201 acttatataa taaggggttt gatatctaac attcaaaccc tttaaatatt ttataatttt
    16261 atgttagatt taaaagtata ttagtgtatt gacagaagaa gtagataata ctattactgt
    16321 tataaatatt tcaatatctt aataaataaa taaaaaacta aaatatgaaa gtaaacaata
    16381 aataaaaaca tatataaata tgggagctta tatagagtaa atggatcaat aagtattgcc
    16441 tgtagaaaag gattaaaaag atttaaagat agaattgagg catttacata taatggatcg
    16501 aaaggtaata ataatgcaat gtaaaggtga ggaaaaaaga gagtctgtaa ttccaaaatg
    16561 cactatttta attggacagt attgagaaaa aatatgagca tattatttag gatattacat
    16621 gatcaaatag tattagaact ttagatagtt aaatgttaat gtatcagacg aaatcttgaa
    16681 aatattttaa atatgtcata tcagtctgta ttaaaatctt taagtgaaag ggacaaagag
    16741 aaactatgaa acaaatagca atagtttaat aaatagatat cattttaatt agtaaatgta
    16801 atgactaaac taataactct aagttattct agggaaaata atatgctgtt aaattatgtt
    16861 gtgagaataa aattttaaaa tattgtggat agtatttttt gtttgtaact tattaataaa
    16921 atttgttata ggaataagtt ctacttatgt tccatttaat aattctttaa tagttgtatt
    16981 actcattttt cttaacttgc aaagtatagt agatatatta tacctagata gtgtagaata
    17041 taatgtggag atgatatttt ctatattgat aaatgtgttt ttaatgttgt tcttttgttc
    17101 atactgcaca tgctaagtta atgtcttcat tttatccact tgaaagattg agaaaaataa
    17161 gaggactaga aagtgctaga tatgaagatc cttactcagg tgggaaagct aactcagtta
    17221 gatatctttc catagctcca agagataata aaatgaaagt tgctggatta gataacttac
    17281 tgtgtggtgg agaaaaagca ggtttatttg taggtcatac tgaagcaata actacaggaa
    17341 gtttagcagg gcacaatagt gtaagattaa gtttaggaat gcctctatta gagcttccaa
    17401 ggaatcttgc agtaggagat attattgctt atgctaatga gagcataggt acgaaagatg
    17461 gacttaagaa aagatttaca tttgcgggtt cagaattttt tgaaagaatg aaggttacag
    17521 gattatatac tacaaacata gaggaaatta ggaagaaaat agatggatta aatttacttg
    17581 gaatatatga agaaaaatta gtataatgaa cttgaagatt ttcagataaa ggaaggttaa
    17641 aaatgaggtt acaaaaattt atggctcaat gtggagttgc ttctagaaga aagtcagaag
    17701 aaataatcca agaaggaaga gttaaagtaa atggaattat agttaaagaa ctaggagtat
    17761 ctatagactc acttgaggat aatataactg tagatgataa aaggataaaa cctgaaggaa
    17821 ataaagtata tatagcttta aataaaccaa ctggctatat aacaaccgtt tcagatcaat
    17881 ttggaaggaa aacggtaata gatttaataa gtgatattaa agagcgtgtt tatccaatcg
    17941 gaagattaga tagtgataca tctggtctac tattattaac aaatgatgga gatcttgcat
    18001 ataaaattac acatcctaaa catgaaataa gtaaaaaata tatagctaaa gtgaaaggta
    18061 tacctaaaga gcataagctt aagcaattta gagaaggact caagatagat gattatatta
    18121 catctaaagc aaaggtaaaa ataattaatg aatttgaagg aaactctata ttagaaatag
    18181 aaattcatga agggaaaaat cgacaagtaa gaaaaatgtg tgaaaaaata ggtcatgaag
    18241 ttatagaatt agaaagaatt gcaattggag aaattaatct taaaaaaata ccactaggaa
    18301 aatggaggtt tttagaaaaa aaggagatag agtacttaaa aaggcagtaa gaaaaagcta
    18361 ctacctctag ctatatatca atcagaggta gtaacttaat atatatttaa ttatcattac
    18421 atatatctaa gatgctatta tagtaaaaga attttaggca aaattattta acggaggaag
    18481 aaaatgatca tagcgagaaa aataaactca gaaaaagaag aagaagtttt aaaaaatata
    18541 ttaaggcagt ataatataaa tgatgaacat aaagataacg atgttactta tattttactt
    18601 ttagatgata aaatagttgg tgtatgtaag ttaacgtgct atcatgatat aggaatatta
    18661 aaatatatag taatagacaa aaaagaaaca gggcaagatt tgggagatgc gctattacga
    18721 tctgctttaa actattgttt tagaaataat atatctagag tttactataa gacaattgat
    18781 gattatttaa ttaaaaaagg atttgaaaaa aacaagaatt acttaaagaa tgtagaacac
    18841 gaggaagaat atttattaga agtcaactta gaacgctttt ttaacagacc ttgtaaatct
    18901 tcaggaggga gataggactt gtataagcat ctcaacagta taataagtat agctaaggag
    18961 ataattgata gaactgtaaa aaaaggtagc atagtggtag atgcaactgt tggaaatggt
    19021 caagatacga taaaattagc tgaattagta ggtgaaactg gaaaggtata tgggtttgat
    19081 attcaaagta tagctataaa aaatacaaaa aagaggttaa tacaagaaaa tttagagaat
    19141 agggtagaat tgataaatga tggacatgaa aaaatagact gctatataag taaagaagtt
    19201 gattttataa tatttaacct aggatatttg cctggaggag accatactat agttacaaga
    19261 aaagactcta cattagaggc tataaagaaa agtttagtta tactaaagcc taacggaatt
    19321 atgcttctag cagtatatca tggacactat gaagggaaag tagagaagag atatatagat
    19381 gaactactta aagaattgag tcagaaaaaa tttaatactt taaaatttga gtttataaat
    19441 cagataaata atccaccaat actttatgcc attgaaaaaa atatgagctt tttaaaggaa
    19501 atgagataat ggaagagaaa attgacttaa taaatttaat taaagaaaag tttgaggact
    19561 taagtaaagg ccaaaaactt atagcaaatt atataatatc taactatgat aaggcagcat
    19621 ttatgacagc ggcaagatta ggtcaagtag taggaataag tgaatctaca gtagtaagat
    19681 ttgctaatac aatgggatat gatggttacc ctaatcttca aagtgaatta caagagttaa
    19741 taaaaagtaa gttaactact gtacagagat taagtatgtc tcaagatgac tattctaaca
    19801 aaaatatagg tgtaaggaaa atactaaaga ctgatatgga gaacataaga catactatag
    19861 atgatataga taccgagata tttgaagagg tagttaatag tattcttaaa gcaaaaaaag
    19921 tttatatatt aggtcttcgt agctctaatg cactttcttc atatctagga ttttacttag
    19981 gtgtaatatt ggatgatgta aaggtagtga acttaggaat aagtgatata tttgaacaac
    20041 ttataagagt cactaaagat gatgtggtta taggtataag ttatccaagg tattcgagga
    20101 gaaccttgga tgcattgaaa tatgtcagag atcagggatg caaagtcata ggaataactg
    20161 atagtgaggc gtctcctata acgagtattg cacacttaac attatttgca aggaacaata
    20221 tggtttcctt tgtagattca ttggtagctc cgatgagtct tataaatgca ttaatagttt
    20281 caataggtat gagagtaaag aatgaggtgg cggaatactt tcaagaacta gaaaatatat
    20341 gggaagaata taatatatat gatagaaagc tatagataga gaagtcattt ttataagatt
    20401 tatttataag agtgacttct ctattttaaa tgaattaatg acgaagaata tcatcataat
    20461 tgattgctaa aaataactag attaatatta ttaaattgat ataataatac tatatttatt
    20521 aaaggaggct tatatgacca aattatattt acttagacat ggacaatctg aatggaatat
    20581 attaaacaaa g
//
