LOCUS       NZ_CP064875.1          25239 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP064875.1 Bacillus toyonensis strain P18 chromosome, complete
            genome.
ACCESSION   NZ_CP064875
VERSION     NZ_CP064875.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:56:40
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2406147
            Orig. end    :: 2431386
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..25239
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[2416147:2421386]"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..15239
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     cand_cluster    1..25239
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..25239
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="betalactone"
                     /region_number="5"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     CDS             complement(906..1475)
                     /locus_tag="ctg1_2292"
                     /transl_table=11
                     /translation="MKMKRKIMMTTALTATLATGALPTTSVFAAEKEAPIQQKEAQVSI
                     QPFAQNNLETAVNAALNGPEVKKIKVFEHEFNVKEIEVVNLGAGKKYVKGQISHHLSFR
                     PDDQFYYEFTVQDGKVIDKPVFNIDRGGWTPFAAPLLSILAAYNGIPVNPNDLNALGQQ
                     LGKVIDGSWEHAAQSIATVVSLSFNE"
     CDS             2134..2976
                     /locus_tag="ctg1_2293"
                     /transl_table=11
                     /translation="MNKKTKRIILLIGTIVGICIFLYLQNNLISITEVKITSSKIPSAF
                     KGYKILQISDLHNKKFGDNQDILIQKVKSINPDIIAITGDLIDSKSYDEEISMQVIREL
                     VKEYPVYFVTGNHEKWSGKYNSLEKELKKNHVTVLRNEHVIIQKGGQEINLLGIDDPEF
                     NNRDINEGSIVKDAIVKAKIETQPNRYNVLLSHRPEFIEEYAEERIDLVFSGHAHGGQV
                     RLPFISGLVAPNQGVLPKYTAGLYEEQNTSMVVSRGLGNSIIPQRILNRPEIVVAQLN"
     PFAM_domain     2278..2787
                     /aSDomain="Metallophos"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00149.30"
                     /description="Calcineurin-like phosphoesterase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2293_0146"
                     /evalue="2.80E-16"
                     /label="ctg1_2293"
                     /locus_tag="ctg1_2293"
                     /protein_end="218"
                     /protein_start="48"
                     /score="60.7"
                     /tool="antismash"
                     /translation="KILQISDLHNKKFGDNQDILIQKVKSINPDIIAITGDLIDSKSYD
                     EEISMQVIRELVKEYPVYFVTGNHEKWSGKYNSLEKELKKNHVTVLRNEHVIIQKGGQE
                     INLLGIDDPEFNNRDINEGSIVKDAIVKAKIETQPNRYNVLLSHRPEFIEEYAEERIDL
                     VFSGHAH"
     CDS             3192..3443
                     /locus_tag="ctg1_2294"
                     /transl_table=11
                     /translation="MHKEYEIEEYTAIEEQIHYYCQCLLVSHPEQIIKYLEKRLEKYAE
                     TLQYAHLYPDTVILPLQQLVIEYSLDLARIRKYMNLET"
     CDS             3630..4355
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 193.8; E-value:
                     5.7e-59)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_2295"
                     /transl_table=11
                     /translation="MQKLSIVLQNVSKSFGKKEVLHDLSLQIEKAEIFGLVGPSGSGKT
                     TLIKLIAGINQASKGDVFVYNINMPNLNEMKRIGYMAQADALYEELSAYENADFIATMY
                     GLKGKHKKERIKEVFDLVQLSQHMKKQVQHFSGGMKKRLSLAIALLHEPEILILDEPTV
                     GIDPLLRKTIWGKFYELKKKGTTIIVTTHIMDEAEFCERLGLIREGNLVAVGTPEELKK
                     RVSSGRIEDVFLLEEGVES"
     PFAM_domain     3690..4115
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2295_0147"
                     /evalue="1.20E-29"
                     /label="ctg1_2295"
                     /locus_tag="ctg1_2295"
                     /protein_end="162"
                     /protein_start="20"
                     /score="103.6"
                     /tool="antismash"
                     /translation="LHDLSLQIEKAEIFGLVGPSGSGKTTLIKLIAGINQASKGDVFVY
                     NINMPNLNEMKRIGYMAQADALYEELSAYENADFIATMYGLKGKHKKERIKEVFDLVQL
                     SQHMKKQVQHFSGGMKKRLSLAIALLHEPEILILDEPT"
     CDS             4352..5371
                     /gene_functions="transport (smcogs) SMCOG1065:ABC-2 type
                     transporter (Score: 73.3; E-value: 2.9e-22)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_2296"
                     /transl_table=11
                     /translation="VRVNGVIIRIIRQFFRDKRSLAMMFGAPMLLLWLLSLVFTQKDYK
                     PHIAVVDVPASIVKVMKNQEASIYEYSKEKAISELEKQKIDAVIHLENGKINLLLEGSD
                     SSKNRAVLQVLQKSTEKNDVSIMKPEVNYLHGSKDFTMFDGLGPVLIGFFTFFFVFILS
                     GVSFVRERLSGTLERLLSTPVRRWEIVVGYIIGFGIFAFIQSVIIVSFSVYVLDLYVAG
                     SIWLTLLITCMLSLTALTLGTFLSAYANNEFQMIQFIPLVIVPQIFFSGLFPIESMNKW
                     LQMLGKLFPLTYGADAMRQVMIRNQGFTEIALDLTVLLLFSLLFAVGNVFALKKHRKI"
     PFAM_domain     4778..5257
                     /aSDomain="ABC2_membrane"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01061.26"
                     /description="ABC-2 type transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2296_0148"
                     /evalue="2.90E-35"
                     /label="ctg1_2296"
                     /locus_tag="ctg1_2296"
                     /protein_end="302"
                     /protein_start="142"
                     /score="121.7"
                     /tool="antismash"
                     /translation="FDGLGPVLIGFFTFFFVFILSGVSFVRERLSGTLERLLSTPVRRW
                     EIVVGYIIGFGIFAFIQSVIIVSFSVYVLDLYVAGSIWLTLLITCMLSLTALTLGTFLS
                     AYANNEFQMIQFIPLVIVPQIFFSGLFPIESMNKWLQMLGKLFPLTYGADAMRQVM"
     CDS             5396..6049
                     /gene_functions="regulatory (smcogs) SMCOG1057:TetR family
                     transcriptional regulator (Score: 95.9; E-value: 6.7e-29)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_2297"
                     /transl_table=11
                     /translation="MKKDWLEELIAATNTDNRNERQMRILEAAVDMFGEKGYASTSTSE
                     IAKRAGVAEGTIFRYYKTKKDLLLAVVMPTLTKFAAPFFVQAFAKEIFKTDYESYEGLL
                     RVVIHNRFEFAKKHFPMIKILIQEVPFQPELKSEIQQLVETELLSHFKKLIVKFQEEGG
                     IIEMPPPSVLRLTLSAVLGFLLTRFLLLPEENWDDELEIENTIQFILYGLTPRR"
     PFAM_domain     5468..5608
                     /aSDomain="TetR_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00440.25"
                     /description="Bacterial regulatory proteins, tetR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2297_0149"
                     /evalue="1.60E-18"
                     /label="ctg1_2297"
                     /locus_tag="ctg1_2297"
                     /protein_end="71"
                     /protein_start="24"
                     /score="66.3"
                     /tool="antismash"
                     /translation="ILEAAVDMFGEKGYASTSTSEIAKRAGVAEGTIFRYYKTKKDLLL
                     AV"
     CDS             6054..7022
                     /locus_tag="ctg1_2298"
                     /transl_table=11
                     /translation="MRQFAKPTIVVSKCLEFDACRYNGEMIPDVTIRNLQPFVTFIPVC
                     PEVEIGLGIPRETIRLVEENGVNKLVQPSTREDVTEKMEQFSNGFLQTISDVDGFILKN
                     RSPSCGTRDVKIYSGFEKAPAKGKGPGLFGGAVLKNFSHLPIEEEGRLSNFIIREHFFT
                     RLFTIAYYKMIKHNKNMKDLVSFQSDNKYLFMAYNQVKQKELGRIIANQKNETIEIVFD
                     NYEKTLYELFLRAPRYTSNVNVCEHIFGYFKTKLKKQEKDYFLELIQKYAEKKIPLSSL
                     LAILKSWAIRFDEKYLLGQTYFEPYPEALVEISDSGKGRDY"
     PFAM_domain     6078..6500
                     /aSDomain="2-thiour_desulf"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04463.14"
                     /description="2-thiouracil desulfurase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2298_0150"
                     /evalue="2.10E-35"
                     /label="ctg1_2298"
                     /locus_tag="ctg1_2298"
                     /protein_end="149"
                     /protein_start="8"
                     /score="121.8"
                     /tool="antismash"
                     /translation="IVVSKCLEFDACRYNGEMIPDVTIRNLQPFVTFIPVCPEVEIGLG
                     IPRETIRLVEENGVNKLVQPSTREDVTEKMEQFSNGFLQTISDVDGFILKNRSPSCGTR
                     DVKIYSGFEKAPAKGKGPGLFGGAVLKNFSHLPIEEE"
     PFAM_domain     6624..6974
                     /aSDomain="DUF1722"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08349.13"
                     /description="Protein of unknown function (DUF1722)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2298_0151"
                     /evalue="1.20E-40"
                     /label="ctg1_2298"
                     /locus_tag="ctg1_2298"
                     /protein_end="307"
                     /protein_start="190"
                     /score="138.5"
                     /tool="antismash"
                     /translation="KYLFMAYNQVKQKELGRIIANQKNETIEIVFDNYEKTLYELFLRA
                     PRYTSNVNVCEHIFGYFKTKLKKQEKDYFLELIQKYAEKKIPLSSLLAILKSWAIRFDE
                     KYLLGQTYFEPYP"
     CDS             7239..8384
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006:acyl-CoA dehydrogenase (Score: 452.4; E-value:
                     2.1e-137)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2299"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1.7e-39, bitscore:
                     133.2, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 5.9e-26, bitscore:
                     88.8, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 1.4e-56, bitscore:
                     189.1, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEFTLTREKQMIKEMVRDFAEKEIAPKAVYYDKTAEFPYETFQKM
                     GELGLLGIPFPEEYGGSGGDTVSYALAVEEIGRACGGTGLSYAATISLGASPIYYFGTE
                     EQKQKYLVPMASGKTLGAFGLTEPNAGSDAGGTQTKAVLDGDEYVISGEKCWITNAEYA
                     NTIIVTAINGVEENGRKRISAFIVPTTSEGLTISSPYDKMGVRASNTCEIVLDGVRVPK
                     ENILGDVNKGFKQFLYTLDGGRISIAALAVGIAQSAFERALQYAKERQQFGKTISNFQA
                     IQFKLADMATEVELARNLVHKAAWLKDNDKPFGKEAAMAKLFASEAASRIANHAVQIHG
                     GYGYMREYEVERHIRDAKLLEIGEGTSEIQRLVIARHLGCR"
     PFAM_domain     7254..7592
                     /aSDomain="Acyl-CoA_dh_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02771.18"
                     /description="Acyl-CoA dehydrogenase, N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2299_0152"
                     /evalue="2.00E-39"
                     /label="ctg1_2299"
                     /locus_tag="ctg1_2299"
                     /protein_end="118"
                     /protein_start="5"
                     /score="134.8"
                     /tool="antismash"
                     /translation="TREKQMIKEMVRDFAEKEIAPKAVYYDKTAEFPYETFQKMGELGL
                     LGIPFPEEYGGSGGDTVSYALAVEEIGRACGGTGLSYAATISLGASPIYYFGTEEQKQK
                     YLVPMASGK"
     PFAM_domain     7602..7892
                     /aSDomain="Acyl-CoA_dh_M"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02770.21"
                     /description="Acyl-CoA dehydrogenase, middle domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2299_0153"
                     /evalue="3.30E-26"
                     /label="ctg1_2299"
                     /locus_tag="ctg1_2299"
                     /protein_end="218"
                     /protein_start="121"
                     /score="91.4"
                     /tool="antismash"
                     /translation="AFGLTEPNAGSDAGGTQTKAVLDGDEYVISGEKCWITNAEYANTI
                     IVTAINGVEENGRKRISAFIVPTTSEGLTISSPYDKMGVRASNTCEIVLDGV"
     PFAM_domain     7926..8372
                     /aSDomain="Acyl-CoA_dh_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00441.26"
                     /description="Acyl-CoA dehydrogenase, C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2299_0154"
                     /evalue="5.20E-56"
                     /label="ctg1_2299"
                     /locus_tag="ctg1_2299"
                     /protein_end="378"
                     /protein_start="229"
                     /score="189.1"
                     /tool="antismash"
                     /translation="NKGFKQFLYTLDGGRISIAALAVGIAQSAFERALQYAKERQQFGK
                     TISNFQAIQFKLADMATEVELARNLVHKAAWLKDNDKPFGKEAAMAKLFASEAASRIAN
                     HAVQIHGGYGYMREYEVERHIRDAKLLEIGEGTSEIQRLVIARHL"
     PFAM_domain     8400..8729
                     /aSDomain="Biotin_carb_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00289.24"
                     /description="Biotin carboxylase, N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2300_0155"
                     /evalue="7.20E-45"
                     /label="ctg1_2300"
                     /locus_tag="ctg1_2300"
                     /protein_end="110"
                     /protein_start="0"
                     /score="152.2"
                     /tool="antismash"
                     /translation="MFQKILIANRGEIAVRIMKTCQKLGIRTVAIYSEADENALHVKMA
                     NEAYLVGGPRVQESYLNLEKIIEIAKKTNVEAIHPGYGLLSENPSFPIRCKEEGIVFIG
                     PSEEII"
     CDS             8400..9737
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RimK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090:acetyl-CoA carboxylase biotin carboxylase (Score:
                     641.5; E-value: 3e-194)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2300"
                     /sec_met_domain="RimK (E-value: 2.8e-06, bitscore: 25.3,
                     seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 4.5e-09, bitscore:
                     34.3, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFQKILIANRGEIAVRIMKTCQKLGIRTVAIYSEADENALHVKMA
                     NEAYLVGGPRVQESYLNLEKIIEIAKKTNVEAIHPGYGLLSENPSFPIRCKEEGIVFIG
                     PSEEIITKMGSKIESRIAMQAADVPVVPGITTNIETAEEAIEIAKQIGYPLMLKASAGG
                     GGIGMQLMETEQTLTKAFESNKTRAQNFFGNGEMYLERYIADAHHIEIQLLADTHGNTV
                     YLWERECSVQRRNQKVIEEAPSPFLDEGTRKAMGEVAVQAAKALGYTNAGTVEFLVDDQ
                     KNFYFLEMNTRLQVEHPVTEEITGLDLVEQQLLIASGEKLSFTQDDVKRSGHAIEARIY
                     AEDPKTFFPSPGKITDLTLPSNIRMDHFLENHVTITPFYDPMIAKVIAHGETREEAISK
                     LENALEELKIEGIKTNTPMLLQVLGDDVFKSGIYTTGFVTKQLVKK"
     PFAM_domain     8745..9365
                     /aSDomain="CPSase_L_D2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02786.19"
                     /description="Carbamoyl-phosphate synthase L chain, ATP
                     binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2300_0156"
                     /evalue="2.50E-75"
                     /label="ctg1_2300"
                     /locus_tag="ctg1_2300"
                     /protein_end="322"
                     /protein_start="115"
                     /score="252.7"
                     /tool="antismash"
                     /translation="KIESRIAMQAADVPVVPGITTNIETAEEAIEIAKQIGYPLMLKAS
                     AGGGGIGMQLMETEQTLTKAFESNKTRAQNFFGNGEMYLERYIADAHHIEIQLLADTHG
                     NTVYLWERECSVQRRNQKVIEEAPSPFLDEGTRKAMGEVAVQAAKALGYTNAGTVEFLV
                     DDQKNFYFLEMNTRLQVEHPVTEEITGLDLVEQQLLIASGEKLS"
     PFAM_domain     9405..9716
                     /aSDomain="Biotin_carb_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02785.21"
                     /description="Biotin carboxylase C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2300_0157"
                     /evalue="6.30E-34"
                     /label="ctg1_2300"
                     /locus_tag="ctg1_2300"
                     /protein_end="439"
                     /protein_start="335"
                     /score="116.4"
                     /tool="antismash"
                     /translation="EARIYAEDPKTFFPSPGKITDLTLPSNIRMDHFLENHVTITPFYD
                     PMIAKVIAHGETREEAISKLENALEELKIEGIKTNTPMLLQVLGDDVFKSGIYTTGFVT
                     "
     CDS             9764..9979
                     /locus_tag="ctg1_2301"
                     /transl_table=11
                     /translation="MMTKVYASMAGNVWKIVVGVGDTVEEEQDVVILESMKMEIPIISE
                     EAGTVMKINVQEGDFVNEGDVLLEIE"
     PFAM_domain     9785..9973
                     /aSDomain="Biotin_lipoyl"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00364.24"
                     /description="Biotin-requiring enzyme"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2301_0158"
                     /evalue="6.90E-17"
                     /label="ctg1_2301"
                     /locus_tag="ctg1_2301"
                     /protein_end="70"
                     /protein_start="7"
                     /score="61.1"
                     /tool="antismash"
                     /translation="SMAGNVWKIVVGVGDTVEEEQDVVILESMKMEIPIISEEAGTVMK
                     INVQEGDFVNEGDVLLEI"
     CDS             10001..10912
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271:2-isopropylmalate synthase (Score: 220; E-value:
                     1e-66)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2302"
                     /sec_met_domain="HMGL-like (E-value: 9e-49, bitscore:
                     164.6, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LKLPNFAVIKEVGPRDGLQNEKKIVGTKDKVKWIQLLTEAGLSYV
                     EVSSFVHPKWVPALADANDVFSELKRDPNVTYAALVPNQNGLERAFLQNVDEVNVFLSA
                     SESHNKSNINKSIKEALTVIEDITKQAIFEGKKVRGYVSTVFGCPYEGDISAAAVDEIC
                     NQLFSYGIYEVSLGDTIGVANPLQVEQVLEHLLKKYDASQFAMHFHNTYGMALANVVKS
                     LEHGITTFDSSCGGLGGCPYAPGASGNVATDDLVHMLHKLGVQTNIDEEKLWRASQFIQ
                     SKLNIQLPSHVYRALQHKTISR"
     PFAM_domain     10025..10840
                     /aSDomain="HMGL-like"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00682.21"
                     /description="HMGL-like"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2302_0159"
                     /evalue="3.10E-49"
                     /label="ctg1_2302"
                     /locus_tag="ctg1_2302"
                     /protein_end="280"
                     /protein_start="8"
                     /score="168.0"
                     /tool="antismash"
                     /translation="IKEVGPRDGLQNEKKIVGTKDKVKWIQLLTEAGLSYVEVSSFVHP
                     KWVPALADANDVFSELKRDPNVTYAALVPNQNGLERAFLQNVDEVNVFLSASESHNKSN
                     INKSIKEALTVIEDITKQAIFEGKKVRGYVSTVFGCPYEGDISAAAVDEICNQLFSYGI
                     YEVSLGDTIGVANPLQVEQVLEHLLKKYDASQFAMHFHNTYGMALANVVKSLEHGITTF
                     DSSCGGLGGCPYAPGASGNVATDDLVHMLHKLGVQTNIDEEKLWRASQFI"
     CDS             10917..11705
                     /NRPS_PKS="Domain: ECH (14-254). E-value: 1.3e-73. Score:
                     239.1. Matches aSDomain: nrpspksdomains_ctg1_2303_ECH.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023:enoyl-CoA hydratase (Score: 254.1; E-value:
                     1.8e-77)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2303"
                     /transl_table=11
                     /translation="MLQLQNISVDYVTPHVVKISLYRERQANSLSLALLEELQTILTEI
                     SEESNTRVVILTGAGEKAFCAGADLKERAGMNEEQVRHAVGMIRTTMEMVEQLPQPVIA
                     AINGIALGGGTELSLACDFRIASENASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKEL
                     IYTGRRISAQEAKEYGLVEFVVPADLLEEKAIEIANQIASNGPIAVRLAKEAISNGVQV
                     DLHTGLQMEKQAYEGVIYTEDRLEGLQAFKEKRKPMYKGE"
     aSDomain        10959..11678
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_2303_ECH.1"
                     /evalue="1.30E-73"
                     /label="ctg1_2303_ECH.1"
                     /locus_tag="ctg1_2303"
                     /protein_end="254"
                     /protein_start="14"
                     /score="239.1"
                     /tool="antismash"
                     /translation="HVVKISLYRERQANSLSLALLEELQTILTEISEESNTRVVILTGA
                     GEKAFCAGADLKERAGMNEEQVRHAVGMIRTTMEMVEQLPQPVIAAINGIALGGGTELS
                     LACDFRIASENASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQEAKE
                     YGLVEFVVPADLLEEKAIEIANQIASNGPIAVRLAKEAISNGVQVDLHTGLQMEKQAYE
                     GVIYTEDRLEGLQAFKEK"
     PFAM_domain     10962..11699
                     /aSDomain="ECH_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00378.22"
                     /description="Enoyl-CoA hydratase/isomerase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2303_0160"
                     /evalue="4.90E-70"
                     /label="ctg1_2303"
                     /locus_tag="ctg1_2303"
                     /protein_end="261"
                     /protein_start="15"
                     /score="235.8"
                     /tool="antismash"
                     /translation="VVKISLYRERQANSLSLALLEELQTILTEISEESNTRVVILTGAG
                     EKAFCAGADLKERAGMNEEQVRHAVGMIRTTMEMVEQLPQPVIAAINGIALGGGTELSL
                     ACDFRIASENASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQEAKEY
                     GLVEFVVPADLLEEKAIEIANQIASNGPIAVRLAKEAISNGVQVDLHTGLQMEKQAYEG
                     VIYTEDRLEGLQAFKEKRKPMYKG"
     CDS             11708..13249
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059:acetyl-CoA carboxylase, carboxyl transferase,
                     (Score: 523.7; E-value: 9.6e-159)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2304"
                     /transl_table=11
                     /translation="VLEQKQQSNNFEERVETIKQGGAPKYHEQNKAKGKLFVRDRLALL
                     FDNGEYVEDALFANCEQTGLPADGVVTATGKIHGRTACVMANDSTVKAGSWGARTVEKI
                     LRIQETAEKLRVPLFYLVDSAGARITDQVEMFPGRRGAGRIFYNQVKLSGKVPQICLLF
                     GPSAAGGAYIPAFCDVVMMVEGNASMYLGSPRMAEMVIGEKVTLEEMGGARMHCSVSGC
                     GDVLCKTEEDAITQARQYISYFPSNYLEKTPLMTPQEPKQFDKTLEQIIPENQNAPFNM
                     KDLINRIIDDGSFFEVKKLFAQELITGLARIDGKPIGIIANQPRMKGGVLFHDSADKAA
                     KFINLCDAYHIPLLFLADVPGFMIGTKVERAGIIRHGAKMISAMSEATVPKISIIVRKA
                     YGAGLYAMAGPAFEPDCCLALPTASIAVMGPEAAVNAVYANKIAALPEEERASFIAEKR
                     EEYKKDIDIYHLASEMVIDGIVHPNNLREELKGRFEMYMSKYQVFTDRKHPVYPV"
     PFAM_domain     11795..13237
                     /aSDomain="Carboxyl_trans"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01039.24"
                     /description="Carboxyl transferase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2304_0161"
                     /evalue="7.10E-160"
                     /label="ctg1_2304"
                     /locus_tag="ctg1_2304"
                     /protein_end="510"
                     /protein_start="29"
                     /score="533.0"
                     /tool="antismash"
                     /translation="NKAKGKLFVRDRLALLFDNGEYVEDALFANCEQTGLPADGVVTAT
                     GKIHGRTACVMANDSTVKAGSWGARTVEKILRIQETAEKLRVPLFYLVDSAGARITDQV
                     EMFPGRRGAGRIFYNQVKLSGKVPQICLLFGPSAAGGAYIPAFCDVVMMVEGNASMYLG
                     SPRMAEMVIGEKVTLEEMGGARMHCSVSGCGDVLCKTEEDAITQARQYISYFPSNYLEK
                     TPLMTPQEPKQFDKTLEQIIPENQNAPFNMKDLINRIIDDGSFFEVKKLFAQELITGLA
                     RIDGKPIGIIANQPRMKGGVLFHDSADKAAKFINLCDAYHIPLLFLADVPGFMIGTKVE
                     RAGIIRHGAKMISAMSEATVPKISIIVRKAYGAGLYAMAGPAFEPDCCLALPTASIAVM
                     GPEAAVNAVYANKIAALPEEERASFIAEKREEYKKDIDIYHLASEMVIDGIVHPNNLRE
                     ELKGRFEMYMSKYQVFTDRKHPV"
     CDS             13299..15239
                     /NRPS_PKS="Domain: AMP-binding (97-521). E-value: 3e-82.
                     Score: 268.2. Matches aSDomain:
                     nrpspksdomains_ctg1_2305_AMP-binding.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     254.5; E-value: 2.6e-77)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2305"
                     /sec_met_domain="AMP-binding (E-value: 5.3e-87, bitscore:
                     290.3, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LKQAVWFPTEEYKEKTRLYGWMKSLGYEDYETFYNKSIEETAWFW
                     GEAEKAVGYQWMKPYTEVLDLENGTPFAQWYNDGTCNVVESALSRWIADEVTRKQPALQ
                     YEGENGTSKSFTYEELDNWVSRVANGLKQAGIEKGDRVTIYMPMIPETVVAMLAVMKIG
                     AIISPIFSGFASDAVMTRVQAAGSKMIITADGFSRRGKIVSLKDEVDKACEHCPTVEKV
                     VIVRHAGNDFTPHHYDFSWSTLEKEKPFIHAEEMHSDDPLMLIYTSGTTGKPKGTVHTH
                     AGFPLKAAFDAGFGMNIKQGDRVLWVTDMGWMMGPFLLFGSLINGATMVMYEGVPDFPE
                     ADRLWETVDKYEITHLGISPTLIRALMAKGDEYVNKHSLKSLEVFASTGEPWNPDPWMW
                     LFETVGKGKVPICNYSGGTEISGGIFGNVLIKPIAPISFNASLPGMAAVVLDDQGKPIR
                     DEVGELCLEKPWVGMTKSFWEDDERYVNTYWSRFENKWVHGDWVIYDGEQYIITGRSDD
                     TLNIAGKRIGPAEYESILVKHINVIEAASIGVPDDVKGEVCHCFVVLRDGVIFTAELKK
                     ELMSLVNSHIGKALCPKDIHVVEDLPKTRNSKVMRRVIKAAYLGKELGDLSSLVNPEVV
                     PHIQGLQSSKL"
     PFAM_domain     13386..13553
                     /aSDomain="ACAS_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF16177.7"
                     /description="Acetyl-coenzyme A synthetase N-terminus"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2305_0162"
                     /evalue="6.50E-12"
                     /label="ctg1_2305"
                     /locus_tag="ctg1_2305"
                     /protein_end="85"
                     /protein_start="29"
                     /score="45.3"
                     /tool="antismash"
                     /translation="YETFYNKSIEETAWFWGEAEKAVGYQWMKPYTEVLDLENGTPFAQ
                     WYNDGTCNVVE"
     PFAM_domain     13584..14861
                     /aSDomain="AMP-binding"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00501.30"
                     /description="AMP-binding enzyme"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2305_0163"
                     /evalue="6.60E-76"
                     /label="ctg1_2305"
                     /locus_tag="ctg1_2305"
                     /protein_end="521"
                     /protein_start="95"
                     /score="255.7"
                     /tool="antismash"
                     /translation="VTRKQPALQYEGENGTSKSFTYEELDNWVSRVANGLKQAGIEKGD
                     RVTIYMPMIPETVVAMLAVMKIGAIISPIFSGFASDAVMTRVQAAGSKMIITADGFSRR
                     GKIVSLKDEVDKACEHCPTVEKVVIVRHAGNDFTPHHYDFSWSTLEKEKPFIHAEEMHS
                     DDPLMLIYTSGTTGKPKGTVHTHAGFPLKAAFDAGFGMNIKQGDRVLWVTDMGWMMGPF
                     LLFGSLINGATMVMYEGVPDFPEADRLWETVDKYEITHLGISPTLIRALMAKGDEYVNK
                     HSLKSLEVFASTGEPWNPDPWMWLFETVGKGKVPICNYSGGTEISGGIFGNVLIKPIAP
                     ISFNASLPGMAAVVLDDQGKPIRDEVGELCLEKPWVGMTKSFWEDDERYVNTYWSRFEN
                     KWVHGDWVIYDGEQYIITGRSDDTLNI"
     aSDomain        13590..14861
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_2305_AMP-binding.1"
                     /evalue="3.00E-82"
                     /label="ctg1_2305_AMP-binding.1"
                     /locus_tag="ctg1_2305"
                     /protein_end="521"
                     /protein_start="97"
                     /score="268.2"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="RKQPALQYEGENGTSKSFTYEELDNWVSRVANGLKQAGIEKGDRV
                     TIYMPMIPETVVAMLAVMKIGAIISPIFSGFASDAVMTRVQAAGSKMIITADGFSRRGK
                     IVSLKDEVDKACEHCPTVEKVVIVRHAGNDFTPHHYDFSWSTLEKEKPFIHAEEMHSDD
                     PLMLIYTSGTTGKPKGTVHTHAGFPLKAAFDAGFGMNIKQGDRVLWVTDMGWMMGPFLL
                     FGSLINGATMVMYEGVPDFPEADRLWETVDKYEITHLGISPTLIRALMAKGDEYVNKHS
                     LKSLEVFASTGEPWNPDPWMWLFETVGKGKVPICNYSGGTEISGGIFGNVLIKPIAPIS
                     FNASLPGMAAVVLDDQGKPIRDEVGELCLEKPWVGMTKSFWEDDERYVNTYWSRFENKW
                     VHGDWVIYDGEQYIITGRSDDTLNI"
     CDS_motif       14085..14141
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_2305_0001"
                     /evalue="7.60E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg1_2305"
                     /protein_end="281"
                     /protein_start="262"
                     /score="24.7"
                     /tool="antismash"
                     /translation="MLIYTSGTTGKPKGTVHTH"
     CDS_motif       14832..14894
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_2305_0002"
                     /evalue="7.80E-04"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg1_2305"
                     /protein_end="532"
                     /protein_start="511"
                     /score="12.3"
                     /tool="antismash"
                     /translation="TGRSDDTLNIAGKRIGPAEYE"
     PFAM_domain     14886..15122
                     /aSDomain="AMP-binding_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13193.8"
                     /description="AMP-binding enzyme C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2305_0164"
                     /evalue="1.50E-20"
                     /label="ctg1_2305"
                     /locus_tag="ctg1_2305"
                     /protein_end="608"
                     /protein_start="529"
                     /score="74.1"
                     /tool="antismash"
                     /translation="EYESILVKHINVIEAASIGVPDDVKGEVCHCFVVLRDGVIFTAEL
                     KKELMSLVNSHIGKALCPKDIHVVEDLPKTRNSK"
     CDS             complement(15705..15872)
                     /locus_tag="ctg1_2306"
                     /transl_table=11
                     /translation="MDKKDLLSQQLDHVSSDALNTPSKAQEQMQETSQKAHNSNKKGNT
                     QSLHVEDLPN"
     CDS             complement(16174..16638)
                     /locus_tag="ctg1_2307"
                     /transl_table=11
                     /translation="MDEFLSFVALNPGSIGPTLPPVQPFQFPTGPTGSTGATGSTGPTG
                     FNLPAGPASITLTSNETTACVSTQGNNTLFFSGQVLVNGSPTSGVVVSFSFSNPSLAFM
                     VPLAVITNASGNFTAVFLAANGPGTVTVTASLLDSPGTMASVTITIVNCP"
     aSDomain        complement(16555..16611)
                     /aSDomain="TIGR03720"
                     /aSTool="tigrfam"
                     /description="exospor_lead: exosporium leader peptide"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2307_0031"
                     /evalue="1.00E-08"
                     /identifier="TIGR03720"
                     /label="ctg1_2307"
                     /locus_tag="ctg1_2307"
                     /protein_end="28"
                     /protein_start="9"
                     /score="32.9"
                     /tool="antismash"
                     /translation="LNPGSIGPTLPPVQPFQFP"
     CDS             complement(16836..17204)
                     /locus_tag="ctg1_2308"
                     /transl_table=11
                     /translation="MGNIPKVSSHQSNPNIPSQQVNPNTQQGNRKKTRRRIITTLAIMV
                     PIIFVLQYSLNNQQEMIKEKQITLNTEQQKLSSVKKDGHSLKNDVKALTSSEEEILKFA
                     RKLYGFSKPNETIFQITE"
     PFAM_domain     complement(16842..17066)
                     /aSDomain="DivIC"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04977.17"
                     /description="Septum formation initiator"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2308_0165"
                     /evalue="2.20E-14"
                     /label="ctg1_2308"
                     /locus_tag="ctg1_2308"
                     /protein_end="121"
                     /protein_start="46"
                     /score="53.1"
                     /tool="antismash"
                     /translation="IIFVLQYSLNNQQEMIKEKQITLNTEQQKLSSVKKDGHSLKNDVK
                     ALTSSEEEILKFARKLYGFSKPNETIFQIT"
     CDS             17840..18220
                     /locus_tag="ctg1_2309"
                     /transl_table=11
                     /translation="METSTFLGLFWGWITVIVSGILFVRPSVLRELKKLVAEDRGFGIM
                     YGFLSIFLGLGTVILHNVWAFNWQGFLTVIAWLALLKGIYIIAYPEPSKKTDFELRILT
                     TRIALAIIGALALWMLIVIYIK"
     CDS             18611..19072
                     /locus_tag="ctg1_2310"
                     /transl_table=11
                     /translation="MIEIKSMIYSYKLKRRIAKDLYGSRDELTMLLNEFNNMKSKVKSD
                     KKKNNMLSRLQLMYQNMKLDKQYSLPFALNSRLLERLEDESIQTTEECVSCLHVMLEIN
                     YEKIKHYGSNTSRSFVPLSQSSICLADFVCLTGFVLLGLLGTITFGGIM"
     CDS             complement(19622..19903)
                     /locus_tag="ctg1_2311"
                     /transl_table=11
                     /translation="MIAGVLRNSIVVMTGGNLKKSIVMMIGGSLKKSIIVMMIGVLRKS
                     IVMMIGGSLKKSIIVMMIGVLNEISVVVNVSLFVVIVKENIGKILMST"
     CDS             20512..20868
                     /locus_tag="ctg1_2312"
                     /transl_table=11
                     /translation="LGSRFNNCKKKCTCKQDDCWEIFEECNKEKHEKCDNSCVQGIRDE
                     LKKLINRTVQINTEGRTYVGTVSSVSCDVVKLAAIPGSVAVIISICKIEAIFPPVTTVT
                     AEFDFNGVDVANKA"
     CDS             20996..21511
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111:GCN5-related N-acetyltransferase (Score: 68.2;
                     E-value: 1.4e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2313"
                     /transl_table=11
                     /translation="VIKLVPFKRSDFKQLINWIHSEQFLIQWSGNAFTYPLNEQQLEKY
                     IESANTLAFKVIDEKTEEVLGHISLGQIDDINKSARIGKVLVGNTKMRGRSIGKHMMKA
                     VLHIAFEELKLHRVTLGVYDFNTSAISCYEKIGFVKEGLLRDSKKVGETYWNLWEMSML
                     EYEWNNKK"
     PFAM_domain     21074..21409
                     /aSDomain="Acetyltransf_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00583.27"
                     /description="Acetyltransferase (GNAT) family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2313_0166"
                     /evalue="2.20E-12"
                     /label="ctg1_2313"
                     /locus_tag="ctg1_2313"
                     /protein_end="138"
                     /protein_start="26"
                     /score="47.4"
                     /tool="antismash"
                     /translation="QWSGNAFTYPLNEQQLEKYIESANTLAFKVIDEKTEEVLGHISLG
                     QIDDINKSARIGKVLVGNTKMRGRSIGKHMMKAVLHIAFEELKLHRVTLGVYDFNTSAI
                     SCYEKIGF"
     CDS             21562..22122
                     /locus_tag="ctg1_2314"
                     /transl_table=11
                     /translation="MNRKTIVITIAAVSGGGKTTITESLTHELTNSKALFFDSYNFDNC
                     PADICKWIDDGANYDEWILTPLIHDIQHLIRDSKLDYIIVDYPFAYLNREMGQFIDVTI
                     FIDTPLDIAMARRILRDFKEDTMSEIHNDLKHYMAHARKAYLEAIHTVKPNSDIVLDGS
                     FSVSEIINHVVEELDRREVIVDG"
     CDS             22115..22855
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2315"
                     /sec_met_domain="Abhydrolase_6 (E-value: 4.4e-07, bitscore:
                     29.0, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 1.4e-08, bitscore: 33.0,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKCIEEYVEVDDFKMYTKVFQGKKWQPVIIMESGYGDYSKAWDY
                     IAERLTEFGTILTYDRAGLGKSGKSSKQRISSEMVKDLRTCLNLLQLKPPYIFVGHSFG
                     GINARLFTVFYPEDMLGTVLVDSTPENYKEVFLPIMSPEFQEAYYKQFAYESSYEEFMF
                     SLGEADRHCKSMSDIPLVVLAAGKKAFYSQAAQLKWLQLQRELLQLSSKNKFIIAEHSG
                     HYIQKDEPHYIIGAVKWILGVGER"
     PFAM_domain     22196..22489
                     /aSDomain="Hydrolase_4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12146.10"
                     /description="Serine aminopeptidase, S33"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2315_0167"
                     /evalue="3.00E-11"
                     /label="ctg1_2315"
                     /locus_tag="ctg1_2315"
                     /protein_end="125"
                     /protein_start="27"
                     /score="43.1"
                     /tool="antismash"
                     /translation="PVIIMESGYGDYSKAWDYIAERLTEFGTILTYDRAGLGKSGKSSK
                     QRISSEMVKDLRTCLNLLQLKPPYIFVGHSFGGINARLFTVFYPEDMLGTVLV"
     CDS             22858..23316
                     /locus_tag="ctg1_2316"
                     /transl_table=11
                     /translation="VYTVFQYNWQVREDWFKWCEQLTVEELLRKRVGGVGSILETLFHI
                     VDVEYSWICDLKGKEVDEPQFKDYQSIQKVKALSHLYNKDLEGFLQSWTEDLENKILKV
                     SWTDKEYKYGEVLRHVIVHEIHHIGQLSIWARELNLQPVSANLIGRGL"
     PFAM_domain     22864..23292
                     /aSDomain="DinB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05163.14"
                     /description="DinB family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2316_0168"
                     /evalue="1.10E-27"
                     /label="ctg1_2316"
                     /locus_tag="ctg1_2316"
                     /protein_end="145"
                     /protein_start="2"
                     /score="97.1"
                     /tool="antismash"
                     /translation="TVFQYNWQVREDWFKWCEQLTVEELLRKRVGGVGSILETLFHIVD
                     VEYSWICDLKGKEVDEPQFKDYQSIQKVKALSHLYNKDLEGFLQSWTEDLENKILKVSW
                     TDKEYKYGEVLRHVIVHEIHHIGQLSIWARELNLQPVSA"
     CDS             complement(23375..24391)
                     /locus_tag="ctg1_2317"
                     /transl_table=11
                     /translation="MQFLKKFTILLLSFIITALIVLYFYLYVNGPIIQAKSAILIDANS
                     GEVIYKKNEETPIQSATLSKLMTEYIVLEQLNDGKIQLDESVKISNELFQAETTPMQVT
                     AKDKTTVRDLLHALLLTGNNRSALALAEHIGGNEDNFTTLMNEKAKQLQLSQPSPFLNS
                     TGANQDTNKQSNTTAKDAAKLATHLVKDFPNVLNMTKLTSYQFTFKNFQVFNTNKMIYS
                     LNENIKLQGVDGLQTSFSTNGNNSFVGTAKLGDTRLISVILESDEENTTFIETKKLLQY
                     GFEPSSYSALQAFKDTLTSWAILLQFKNLIIQTMMIFFIITILMFLHLRQRKSEDFN"
     PFAM_domain     complement(23594..24301)
                     /aSDomain="Peptidase_S11"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00768.22"
                     /description="D-alanyl-D-alanine carboxypeptidase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2317_0169"
                     /evalue="1.10E-52"
                     /label="ctg1_2317"
                     /locus_tag="ctg1_2317"
                     /protein_end="266"
                     /protein_start="30"
                     /score="178.9"
                     /tool="antismash"
                     /translation="PIIQAKSAILIDANSGEVIYKKNEETPIQSATLSKLMTEYIVLEQ
                     LNDGKIQLDESVKISNELFQAETTPMQVTAKDKTTVRDLLHALLLTGNNRSALALAEHI
                     GGNEDNFTTLMNEKAKQLQLSQPSPFLNSTGANQDTNKQSNTTAKDAAKLATHLVKDFP
                     NVLNMTKLTSYQFTFKNFQVFNTNKMIYSLNENIKLQGVDGLQTSFSTNGNNSFVGTAK
                     LGDTRLISVILESD"
ORIGIN
        1 cctcaaatga tagtgatcca ctttcaggag tagtttcttc ttttaagcgc attaaaattg
       61 tttctgtcgg ataatctttt aaaaattgaa ttgcctcttt taatacatct tcaaacattg
      121 ctttttgatt tacaatccca tggtacattg caaaagaatc ttttacacgt ttaacacgca
      181 tatctacata tcgaattcca gaatttaatt gttgaggtag actcatagtt tgatttcttg
      241 tcaaattttc atcaagaaaa cttgctccat gtaaagccat tgtaccgtga gtccctggaa
      301 tagatatttt acttagtttt gttgaatctt ctactttcga catccacgat ggattttgat
      361 atcctatatt ggattcatag gaataacctg gatgactatc agctaaaata ggagatggtg
      421 tacttaaact tgctagtgta aaacatgtga ggatgctaat tttaaagaaa tttattattt
      481 ttattttgtt cattttatct ctcctgacct ttaaacaata gattaagatg attttgtact
      541 atatttattg ttttcatttt aaagtaatga aattttgtgt ttgaaaataa ttaaaaatag
      601 ggggagtaac ttatttgaga ctttaataat ttgttgttat gaattgtact taataaccaa
      661 acggattctt aaagaatcga agtatagact cgaaaaaaca accttttatc gtattgtata
      721 caaacaaaac agaagcctta aaaaagactt ctattctgtg acatataatg aatgataagg
      781 tggttaacaa atcaagataa tgtgactgag tggtaaaaat ctatttatag ctgtttcaga
      841 atctcttata acaaggttac ctacgaaaaa tgggcctctg caaggctaat aaaaattaaa
      901 aagttctact cattaaaact taaactaact acagttgcga tagattgggc tgcatgttcc
      961 cagcttccat ctataacttt tccaagctgc tgaccaagtg catttaaatc atttgggtta
     1021 actggaatcc cattataggc agcaagaatt gataaaagtg gagcagcaaa tggtgtccaa
     1081 ccacctctat caatattaaa tacaggctta tctattacct ttccatcttg cactgtaaac
     1141 tcataataaa attgatcatc tggacgaaaa cttaaatgat gagaaatttg tcccttaaca
     1201 tatttttttc cagcacctag atttactact tctatttctt ttacattaaa ttcatgctca
     1261 aatactttta tttttttgac ttctgggcca tttaaggcag cattaacggc tgtttccaaa
     1321 ttattttgtg caaatggttg aatactcact tgtgcctctt tttgttggat aggagcctct
     1381 ttttcagcag caaacaccga tgtagtcggt agtgcacctg tagctaatgt agctgtaagt
     1441 gctgttgtca tcatgatttt tcttttcatt ttcatagttt tccttcctct cttaaagtta
     1501 tgatatataa tcttttaaag actgacacgg tgcaatatat tatttcataa tgcacgcaaa
     1561 aaatagttta agaattatgt gaaactatgt cagaaaatta aagttaatta tatattcatt
     1621 tacaatgata tctatctaca cacatttttt caattttcta ataaataata taataataac
     1681 ttttcataag ggaatttaat gttttaattc tctctatata cgctttaaac aaattaaaat
     1741 cgtagtggta ataatatatt tgcaagcaaa tgtcgtatat acttcgagaa aaatacacaa
     1801 tttttttata aaaaacttta ggaattatca ttatatcgtt attaactaag taagataaat
     1861 gataatatga tgaagagctt ccagggattc gctataaatt cactagagaa tgagcatgat
     1921 atcatacact catgcaggac gcctaggata ttaaagctcc actttatagt aagttaatac
     1981 gaaggagatt ggaaacagca gtaagtgttt attagagacg tataacacta tgaaaaatac
     2041 ttcaaattaa ttggaaagtt tcagtttttt gaattcaaag ggcacggaat gtttattaga
     2101 attgtagttc tgattaagat tttaggagga aaaatgaaca agaagactaa aagaatcata
     2161 ttacttatcg gtacaatagt aggtatttgt atctttttat atttacagaa caatttaata
     2221 agtataactg aggttaaaat aacctctagt aaaattccct ccgcttttaa agggtataaa
     2281 attctacaaa tttcagattt acataataaa aaatttggtg ataatcaaga cattttaatt
     2341 caaaaagtaa aaagcataaa tccagatatt attgctatta ctggtgattt aatagacagt
     2401 aaatcgtacg atgaagaaat tagtatgcaa gtaatacgag aacttgtaaa ggagtatccg
     2461 gtatattttg taacaggaaa ccatgaaaaa tggtcaggaa aatataacag tttagaaaaa
     2521 gaattaaaga aaaaccatgt tactgttttg agaaatgaac atgtaataat acaaaaaggc
     2581 ggacaagaaa taaacttgtt aggtattgat gatccggaat ttaataacag agatattaat
     2641 gaaggaagta ttgtaaaaga tgcaattgta aaagcgaaaa ttgaaacgca accaaataga
     2701 tataatgtat tattatccca taggccagaa tttattgagg agtatgcaga ggagcgaata
     2761 gatttagttt tctcagggca tgctcatggt gggcaagtta ggttaccatt tatcagcgga
     2821 ttagttgctc caaatcaagg tgttttacct aaatatacag caggtttata tgaagaacaa
     2881 aatacatcaa tggtggttag tagaggatta ggcaatagta tcattccgca aagaattttg
     2941 aataggccag aaattgtagt cgcccagtta aattaaattg ggcgactttt tatgtacaga
     3001 atgagtaaag gggctttatg tattttgtac gagttaacat tacaattttg ttaaaaattt
     3061 tctacgttac ataaagtaac aaaatttgac ctgaagagtt tgttatagtg taaataatca
     3121 aaaaacttaa aaattagtcg agtgaaaagt gtgataagga atttatgtaa aaaacttaaa
     3181 ggggtgtaca catgcataaa gaatatgaaa ttgaagagta tacggcgatt gaggaacaaa
     3241 tacattatta ttgtcaatgt ttattagtga gccatcctga gcaaattata aaatatttag
     3301 aaaaaagatt agaaaaatat gcagaaacat tacaatatgc acatttatat cccgatacag
     3361 ttattttacc attacagcaa ttagttatcg aatattcttt agaccttgct agaattagga
     3421 agtatatgaa tttagaaaca taaagtaaaa tgcatagttt aaatgaaaca gagtcgactt
     3481 taagaaagta tattctaatg tcgattctgt ttcattgttt aatattgttg attgaaaata
     3541 aatactaatc aatgaagttt gacatataat tacgcaagag taaaataaaa gtgagtactc
     3601 actcatttta tagaaaagag ggataataca tgcaaaaact ttcaattgtt ttacagaatg
     3661 tatcgaaaag ttttgggaaa aaagaagttt tacacgatct ttcattacaa attgaaaaag
     3721 cagagatatt tggtttagtt gggccttcag gatcagggaa aacgacgctt attaaattga
     3781 ttgcaggtat taatcaggca tctaaaggtg atgtatttgt atacaacatt aacatgccaa
     3841 atttaaatga gatgaaaaga attggctata tggctcaagc tgatgcatta tacgaagaac
     3901 tatcagcata tgaaaatgca gattttattg caacgatgta tggattaaag ggaaagcata
     3961 aaaaggaaag aatcaaagag gtttttgacc tggtacaatt atcacaacat atgaaaaagc
     4021 aagtacagca tttttcaggt gggatgaaaa agcgtctatc attagcaata gcacttcttc
     4081 atgaacctga aatattaatt ttagatgagc caacagtggg gatagatccg cttcttagaa
     4141 aaacaatctg gggaaaattt tatgaactta aaaagaaagg cacaactatt attgtaacga
     4201 cgcacattat ggatgaagca gagttttgtg agcgtctagg gttgattaga gaagggaact
     4261 tagttgcggt tggaacgcca gaggaattga aaaaacgtgt atcatctgga cgaattgaag
     4321 atgtcttttt gttagaagag ggggttgaat cgtgagagtt aatggtgtaa tcattcgtat
     4381 tattcgtcaa ttttttcgag ataaacgttc gttagccatg atgtttgggg caccaatgtt
     4441 attactttgg ctattgtctt tagtatttac acaaaaagat tataaaccac atattgctgt
     4501 agttgatgtg cccgcttcta tagtaaaagt gatgaaaaat caagaagcct caatttatga
     4561 atatagcaaa gagaaagcga tttctgagtt ggaaaaacaa aagatcgatg cagtaattca
     4621 tttagagaat ggaaaaataa atcttttgtt agaaggcagt gattcgtcga aaaaccgtgc
     4681 tgtactccaa gtattgcaaa agagcacaga gaagaatgat gtatcgatta tgaaacctga
     4741 agtgaattat ttacatggct ctaaagactt tacgatgttt gatgggctcg gtcccgtgtt
     4801 aattggattc tttacatttt tctttgtatt cattttgtca ggagtttctt tcgtaagaga
     4861 acgtttaagt ggtacattag agcgattatt gtccacacca gttagacgat gggaaatagt
     4921 tgttggatat ataattggtt ttggaatttt tgcattcata caatctgtta taattgtaag
     4981 tttttcagtc tatgttttag atttatatgt agcaggttct atatggctaa cgctacttat
     5041 tacatgtatg ctctctttaa cggcactaac attagggacg tttttatcag catacgcaaa
     5101 taatgaattt caaatgatcc agtttatacc gctagttatt gtgccacaaa tcttcttttc
     5161 tggcttgttt ccaattgaat ctatgaataa gtggctacaa atgttaggga aattatttcc
     5221 actcacatac ggcgctgatg caatgaggca agtgatgatt cgaaatcaag gatttacaga
     5281 aattgcattg gatcttactg tattactact tttttcacta ttatttgcag tagggaatgt
     5341 atttgcttta aagaaacatc gcaaaatata ataatgacaa aaaggggctt tgtacatgaa
     5401 gaaggattgg cttgaggaat tgattgctgc aactaatact gataatcgaa atgaacgtca
     5461 aatgcgtatt ttagaagcag ctgttgatat gtttggagaa aaaggatatg cttcaacttc
     5521 aacaagtgaa attgcaaagc gtgctggtgt agcggaagga acgattttcc gctactataa
     5581 gacgaaaaaa gatttattgt tagcggtcgt aatgccaact ttaacaaagt ttgctgcacc
     5641 atttttcgta caagcttttg cgaaagagat atttaaaact gattatgaat cgtatgaagg
     5701 gcttttaagg gtagtcattc ataatcgatt tgaatttgcc aaaaagcact ttccaatgat
     5761 taaaatatta attcaagaag tgccgtttca gccagagcta aaaagtgaaa tacaacaatt
     5821 agtagaaaca gaactgcttt cacattttaa aaagttaatt gtaaagtttc aagaagaagg
     5881 gggaattatt gagatgccac caccttccgt gttacggctt acattatcag ctgttttagg
     5941 atttctatta actcggtttt tattattacc tgaagagaat tgggatgatg aattggaaat
     6001 tgaaaatacg attcaattta ttttgtacgg actaacgcca cggaggtaat gaaatgcgac
     6061 aatttgcaaa acctacaatc gtcgtaagta aatgtttaga atttgatgct tgtcgttata
     6121 atggagaaat gattccggat gtaacaatac gaaatttgca gccatttgtt acatttatac
     6181 ctgtttgtcc agaagtcgag attggattgg gaattcctcg tgaaacgata cgactcgtag
     6241 aagaaaatgg tgtgaataaa cttgtgcaac cgtcgacaag agaagacgtt actgaaaaaa
     6301 tggagcaatt ttcaaatgga tttttacaaa cgatatccga tgtggatgga tttattttaa
     6361 agaatcgctc gccaagttgt ggtacgcgtg atgtgaaaat ttattctggt tttgaaaaag
     6421 cgccagcaaa aggaaaggga ccaggcttat ttggcggagc agtattaaaa aatttttcgc
     6481 accttccaat tgaagaagaa ggtagattgt cgaattttat tattagagaa catttcttta
     6541 caaggttatt tacaatcgca tattacaaaa tgattaaaca taataaaaat atgaaagacc
     6601 ttgtatcgtt tcagtcggac aataaatatt tatttatggc atataatcag gtaaaacaaa
     6661 aagaattagg gcgtattatt gcaaatcaaa aaaatgaaac gattgaaatt gtatttgata
     6721 attatgagaa gactttatat gaattatttt tgcgcgcgcc ccgctataca tcgaatgtaa
     6781 atgtatgtga acatattttc ggatatttta aaacgaaatt aaaaaaacaa gaaaaagatt
     6841 attttttaga actgatacaa aagtatgcag aaaagaaaat accacttagt agtttgcttg
     6901 caattttaaa atcatgggcc attcggtttg atgaaaagta tttattagga caaacatatt
     6961 ttgagccata tcctgaagcg ttagtagaaa tttctgattc gggaaaaggt agagattatt
     7021 aaacaataaa ttacataatt cgacatgaaa cttcctatgt tgttgtagaa caatgtagga
     7081 atttttttgt gcattagtac agaatctgtt ttaaaattaa gttatgacag aattgtagca
     7141 attgtctaac taatattctt gtcttttaag aagtaatgtt tgtagtagaa actcgcacgc
     7201 tgtcgaaact caatattcga taaggggtgt gtagcggaat ggaatttact ctaactcgcg
     7261 aaaaacaaat gattaaagaa atggtacgtg actttgctga aaaggaaatc gcaccgaaag
     7321 ctgtgtatta tgacaaaact gcagagtttc catatgaaac atttcaaaaa atgggcgaac
     7381 taggattatt aggcatccca ttcccagaag agtatggagg ttcaggtggc gatacagtat
     7441 cgtacgcgct agcagttgaa gaaattggtc gtgcttgtgg tggtacagga ttaagctacg
     7501 ctgcaacaat ttcattaggt gcttctccaa tttattattt cggtacagaa gaacaaaaac
     7561 aaaaatattt agttccaatg gcatcaggta aaacgttagg cgctttcgga ttaacggagc
     7621 caaacgctgg atcagatgca ggaggcacac aaacgaaagc ggtattagat ggtgatgagt
     7681 atgtaatcag tggtgaaaag tgctggatta caaacgcaga gtatgcaaat acaattattg
     7741 taaccgctat caacggtgtt gaagagaatg gtagaaaacg tatttctgca tttatcgtac
     7801 cgactacaag tgaaggatta acgatctcaa gtccttacga taagatgggt gttcgcgctt
     7861 ctaatacttg tgaaatcgta cttgatggtg tgcgtgtacc gaaagaaaat attcttggtg
     7921 atgttaataa aggatttaaa caattcttat atacacttga tggaggacgt atttcaattg
     7981 cagcattagc agtaggtatt gcacaatctg catttgaacg tgcattgcaa tatgcgaaag
     8041 aacgtcaaca atttggaaaa acaatttcta atttccaagc gattcaattt aaattagcgg
     8101 atatggcgac tgaagtagag ttagcacgta atttagtaca taaagcagct tggttaaaag
     8161 ataacgataa acctttcggt aaagaagcgg ctatggcaaa actatttgca tctgaagcag
     8221 ctagtcgtat tgcgaatcat gcagtacaaa ttcatggcgg ttatggctat atgcgtgaat
     8281 atgaagttga aagacatatt cgtgatgcaa aactgttaga aattggtgaa ggaacttctg
     8341 aaattcaacg tctcgtaatt gctagacatt taggatgtag ataaaaagga ggaatcacta
     8401 tgtttcaaaa aatattaatt gccaatcgcg gggaaatcgc agttcgcatt atgaaaactt
     8461 gtcaaaaact tggaattcgt accgtcgcta tttattctga ggctgatgaa aatgcccttc
     8521 atgtaaaaat ggcaaatgaa gcttatctag taggtggtcc acgagttcaa gaaagctatt
     8581 taaaccttga aaaaattatt gaaatagcta agaagacaaa tgttgaagca atccatccgg
     8641 ggtacggatt attatcagag aatccatctt ttccgattcg ctgtaaagaa gaaggaatcg
     8701 tatttattgg tccttcagaa gaaatcatta cgaagatggg aagtaaaatt gagtcacgta
     8761 tagcaatgca agcagcagat gtaccagtag ttccaggtat tactacaaat attgaaactg
     8821 ctgaagaggc aattgaaatt gcaaaacaaa ttggttatcc attaatgctt aaggcatccg
     8881 cgggcggcgg aggcattgga atgcagttga tggaaactga gcaaacgctc accaaagcat
     8941 ttgaaagtaa caaaacaagg gcacaaaatt tcttcggtaa tggagaaatg tatttagagc
     9001 gttatattgc agacgcgcat catattgaaa ttcagctttt agcagataca catggtaaca
     9061 cagtgtactt atgggaacgt gaatgttccg tacagcgccg aaatcaaaaa gtaatcgaag
     9121 aagcaccttc acctttttta gatgaaggta cacgaaaagc aatgggagaa gtggctgtac
     9181 aagctgctaa agctcttgga tatacaaatg caggtacagt tgagtttctt gtagatgatc
     9241 agaaaaattt ctatttctta gaaatgaata cgagattaca agtagagcat cccgttacag
     9301 aagaaattac ggggttagat cttgtagaac aacaacttct tatcgcaagt ggagagaaac
     9361 tatcatttac tcaggatgat gtaaaacgta gtggtcatgc cattgaagca cgtatttatg
     9421 cagaagaccc gaaaacattc ttcccgtcac ctgggaaaat tacagattta acattaccat
     9481 caaatatacg tatggatcac tttttagaga atcatgtaac aattacaccg ttttatgatc
     9541 caatgattgc aaaagtcatt gctcatggtg aaactcgtga agaggcaatt tcaaaattag
     9601 aaaatgctct agaggagttg aaaattgaag gtattaaaac aaatacaccg atgctactgc
     9661 aagtgctcgg agacgatgtg ttcaaaagtg gtatttatac aacgggtttc gtaacgaaac
     9721 agcttgttaa aaaataagat ttatgaatat taagggggaa aaaatgatga cgaaagtata
     9781 tgcatcgatg gcaggaaatg tttggaagat agttgtagga gtaggagata cagtagagga
     9841 agagcaggat gtcgtcattt tggaatctat gaaaatggaa attccaatca tttcagaaga
     9901 agctggcaca gttatgaaaa ttaatgtgca agaaggtgat tttgtaaatg aaggagatgt
     9961 attactagaa attgaatagg gagatatagg gggaagcgaa ttgaaactac ctaattttgc
    10021 tgtcattaaa gaagtagggc cacgtgatgg cttacagaat gaaaaaaaga ttgttggcac
    10081 aaaagataaa gtaaaatgga ttcaactact tacagaagcc ggattgtcgt acgttgaagt
    10141 ttcctcattc gttcacccaa aatgggttcc tgccttagcg gatgcaaatg atgtcttttc
    10201 tgagctaaaa agggatccca atgttacata tgctgcgctt gttccaaatc aaaatggttt
    10261 ggaacgagct tttttgcaaa atgtagatga ggtgaatgtt tttttatcag cgagtgaatc
    10321 tcataataaa agtaatatta ataaatcaat taaagaagca ttaactgtta ttgaagatat
    10381 aacaaaacag gcaatattcg aagggaaaaa ggttagaggt tatgtttcta ctgtatttgg
    10441 atgtccgtat gagggagata taagtgccgc agcagttgat gaaatatgta atcaactatt
    10501 ttcatacggc atttatgaag tttctctcgg tgacacgatt ggtgtagcga atccattaca
    10561 agtagaacaa gtattagaac atctattaaa gaaatatgat gcttcgcagt ttgcaatgca
    10621 ttttcataat acgtatggga tggcacttgc aaatgtagtg aagtctttag aacacggtat
    10681 tacaacgttt gatagttctt gtggtggact cgggggatgt ccatatgcac cgggagcatc
    10741 aggaaatgtt gcaactgatg atttagtgca tatgctccat aagttaggtg tccaaacaaa
    10801 tatagacgaa gaaaagttat ggagagctag tcaatttatt caaagtaagt tgaatatcca
    10861 attaccgagt catgtgtata gagcgcttca acataaaacg ataagtaggt gagaagatgc
    10921 tacaattaca aaatatttca gttgactatg taacaccgca tgttgtaaag atttcgttat
    10981 atcgtgaaag acaagcaaat tctttatctt tagcgttatt agaagaattg caaacaatat
    11041 taacggaaat aagtgaagag tcaaatacac gtgtagttat tttaacaggg gctggtgaaa
    11101 aagcgttttg tgctggcgca gatttaaaag aacgagctgg tatgaatgaa gagcaagttc
    11161 gccatgcggt tggtatgatt cgtactacta tggaaatggt ggaacaatta ccacaaccag
    11221 ttattgcagc tattaatgga attgctcttg gtggtggtac ggaattgagt ttagcctgtg
    11281 actttagaat cgcttctgaa aatgcaagcc ttggtctgac tgaaactacc cttgcaatta
    11341 tacctggagc aggtggtacg cagcgtttac cgagattaat tggtgttggt agagcgaaag
    11401 aattaattta tacaggaaga cgtatttcgg cgcaagaagc gaaagaatat ggtttagtag
    11461 aattcgtcgt accagctgat ttactagaag agaaagcgat tgaaattgca aatcaaattg
    11521 ctagtaatgg tcctattgca gttcgattag caaaagaagc aatttctaat ggtgttcaag
    11581 tagatttaca taccggatta caaatggaaa aacaggcgta cgagggtgta atctatacgg
    11641 aagatagatt agaaggatta caggcattta aggaaaaacg caaaccgatg tataaggggg
    11701 agtaaatgtg ttagaacaaa aacaacaatc aaataatttt gaagaacgag ttgaaacgat
    11761 taaacaaggt ggagcaccga aatatcatga acaaaacaaa gcaaaaggaa aactatttgt
    11821 tcgagatcgt ttagctcttc tatttgataa tggcgaatat gtagaagatg cattatttgc
    11881 aaattgtgag caaacagggt taccggctga tggtgttgta actgcaactg gtaaaataca
    11941 tgggcgtact gcgtgcgtaa tggcaaatga ttcaactgtg aaagccggat catggggagc
    12001 tcgtacagtt gaaaagattt tacgtattca agaaacggct gaaaagttac gtgttccatt
    12061 attttattta gttgactctg ctggagcgcg tattacagat caagtagaaa tgttcccagg
    12121 gcgccgcggt gcgggaagaa tcttttataa ccaagtgaaa ttatcaggta aagttccgca
    12181 aatttgttta ttatttggtc cttctgctgc tggtggtgca tatattccag ctttttgtga
    12241 cgttgttatg atggtggaag gtaatgcatc tatgtattta ggatctccac gtatggctga
    12301 aatggttatc ggtgagaagg taactttaga agaaatgggc ggggctcgta tgcattgctc
    12361 agtatcagga tgcggagacg ttttatgtaa gacagaagaa gatgcaatta cacaggctag
    12421 acaatacatt tcatattttc caagcaacta cttagaaaag actccattga tgacacctca
    12481 agaaccgaaa cagttcgata aaacgttaga acaaatcatt ccagaaaatc aaaatgctcc
    12541 tttcaatatg aaagatctga ttaacagaat tatagatgac ggctcattct ttgaagtgaa
    12601 aaaattattt gctcaagaac tcattacagg tttagcacgc attgatggta agccaatagg
    12661 tattattgca aatcagccgc gtatgaaagg tggcgtttta ttccacgatt cagctgataa
    12721 agcagcgaag tttattaatt tatgcgatgc ataccatatt ccattattat tccttgcaga
    12781 tgtaccagga tttatgattg gtacaaaagt agagcgcgct ggtattattc gtcacggtgc
    12841 aaaaatgatt tctgcaatga gtgaagcaac tgtaccgaaa atttctatca ttgttcgaaa
    12901 agcatatgga gctggtttat atgcaatggc aggtccggca tttgaaccag attgctgctt
    12961 agcattaccg acagcttcta ttgctgtaat gggtccagaa gcagcggtca atgctgtata
    13021 tgcaaataaa attgcggctt taccagaaga agagcgtgca agcttcatag ctgaaaaacg
    13081 tgaagagtat aagaaagata ttgatattta tcatttagca tcagagatgg tgattgatgg
    13141 tattgttcat ccaaacaatt tacgtgaaga gttaaaaggg cgtttcgaaa tgtatatgag
    13201 taaatatcaa gtattcacgg atcgtaaaca tcctgtatat ccagtttaaa agccctattt
    13261 agggctttct tgctcaaaaa gtcaaggagg ggaaaacatt gaaacaagca gtttggtttc
    13321 caacagaaga gtataaggaa aaaacacgtt tatatggttg gatgaaatca ttgggatatg
    13381 aagactatga aactttttat aataaatcta ttgaggaaac agcttggttt tggggagagg
    13441 cagaaaaagc agttggctat caatggatga aaccttatac agaagtgtta gatttagaaa
    13501 atggtacgcc atttgcacag tggtataatg atggaacatg taacgttgta gaatcagctt
    13561 tatcccgctg gattgcggat gaagtgacaa gaaaacagcc agcacttcag tacgaagggg
    13621 aaaatggaac ttcaaaatca tttacatatg aagagcttga caattgggta agccgtgtgg
    13681 ccaatggttt gaaacaagcg ggtattgaga agggcgatcg tgtaacaatt tatatgccga
    13741 tgattccgga aacagttgtt gcgatgctag ctgtaatgaa aatcggagca attatttcac
    13801 caatattttc gggatttgct tcggatgcag ttatgacacg cgtacaagca gctggttcaa
    13861 aaatgattat taccgcagat ggattttcac gccgcgggaa aattgtttct ttaaaggatg
    13921 aagtagataa agcttgtgaa cattgcccga ctgttgaaaa ggtggtaatt gttcgtcatg
    13981 caggaaatga ttttacaccg catcattatg acttttcatg gagtacgcta gaaaaagaaa
    14041 aaccattcat acatgccgaa gaaatgcata gtgatgatcc tttaatgctc atatatacat
    14101 caggaacgac tggtaagccg aaaggaacgg tacacacgca tgcaggattt cctttgaaag
    14161 cagcttttga tgcaggattt ggaatgaata ttaaacaagg tgatcgtgta ttatgggtaa
    14221 ctgatatggg ctggatgatg gggccatttt tattattcgg ttcactcata aatggtgcaa
    14281 cgatggttat gtacgaaggt gttccagact ttccagaagc agatcgctta tgggagacgg
    14341 ttgataaata tgaaattact catctcggta tttcgccaac gttaatccgt gcattaatgg
    14401 caaaaggtga tgagtatgtg aataaacatt ctttaaagag tttagaagta ttcgcatcaa
    14461 caggagagcc ttggaatcct gatccatgga tgtggctgtt tgaaacagtt ggaaaaggaa
    14521 aagtgccaat ctgtaactat tcaggcggaa ctgaaatttc tggtgggatt ttcggtaatg
    14581 ttctgattaa gccaatcgca ccaattagtt ttaacgcatc gttaccaggt atggctgcgg
    14641 ttgtacttga tgatcaaggt aaaccaatcc gtgatgaagt tggagaatta tgtttagaga
    14701 aaccttgggt tggaatgacg aaaagtttct gggaagacga tgagcgttat gtgaacacat
    14761 attggtcacg atttgaaaat aaatgggttc atggtgactg ggttatttat gatggtgaac
    14821 aatatatcat tacagggcgt tcagatgata cgctaaatat tgctggtaaa cgtattgggc
    14881 ctgctgaata tgagtctatt cttgtgaaac atattaatgt aatagaagca gcttccattg
    14941 gtgtacctga cgatgtaaaa ggtgaggttt gtcattgctt tgtagtatta cgagatggtg
    15001 taatatttac agcagaatta aagaaagaat taatgagttt agtaaattct catatcggaa
    15061 aagcattatg tccaaaggat atccacgttg tagaggattt gccaaaaaca cgtaattcta
    15121 aagtaatgcg acgcgtcatc aaagcggctt acttaggaaa agaattagga gatttatcat
    15181 cacttgtaaa tccagaagta gttccacata ttcagggtct acagtctagt aaattataaa
    15241 tgtaggaatg agctctatgt aaatggagct catttttcat gtttataaaa agagaagaag
    15301 taaatttgaa gtagtaaaat tctacttgta ttattacgac gtatgtttgt tttatagttt
    15361 ttatcaaaat aggattgtgg catgtctatt cattggagag attgaattgt gttaaggatg
    15421 aaaatttagt gaagcgaaaa gtaatgaata aaaggagaaa tccctggggg acagggattc
    15481 actaagggag aaagtattgt cgtgcaatgt cgaaatttgg cgtattcgac aaattaatat
    15541 tatcacgaat tttcaggaga ttgtgatagg gaatgtgtca aaaatgtgta cgtatttcct
    15601 attaaagtgt tatgtaaata ggaaaaggga aaaaattaag ttcactcgtt cttaagaatt
    15661 tttcccctta aaatttagta tttgttcgtt attctatata cgtcttaatt tggtaaatct
    15721 tcaacatgta aagattgagt attgcccttt ttgtttgaat tatgtgcctt ctgagatgtt
    15781 tcttgcattt gctcttgggc tttactagga gtattcagcg catcagatga tacatgatca
    15841 agttgttgac ttaataaatc ttttttatcc atgttatgta gctccttttt gaactttgat
    15901 ataaaaacga agcgttttta aatagttacg tgggtattat gtatctttga atggaattat
    15961 atacacaaac tacattgaga agttaactac ttataaaaat tacctgtgat gacaagctga
    16021 agaaatataa agatcattag tgattaataa aagcattatt ttagtagggt gttacgaaat
    16081 ttcatttaaa aggaacatcc caatgataaa aaagagcact gtaaatcagt gctcatctta
    16141 tcagaaactg cttagtcctt aaaagcaaaa ccattacgga caattcacaa tggtaatagt
    16201 gacgctagcc attgttccag gagaatcaag aagtgaagca gtaacggtta ctgttccagg
    16261 cccattagcg gctagaaata cagcggtaaa gttacctgaa gcattggtaa tgacagcaag
    16321 aggaaccatg aaagcaagag aagggttact aaatgaaaaa ctgaccacta ctcctgaagt
    16381 aggactaccg tttactaata cttgccccga aaaaaataaa gtattatttc cttgagtgga
    16441 tacacatgct gtggtttcgt tagaagtcaa ggtaatagat gcaggcccag cgggaagatt
    16501 aaatccagtt ggtccagttg aaccagtagc tcctgtagaa cctgtgggac cagtagggaa
    16561 ttgaaagggt tgaacaggtg gaagtgtagg tccaatagaa cccggattaa gtgcaacaaa
    16621 agataaaaac tcgtccatta tttatcacct ctaaaaattg tattactaat agtaaatgta
    16681 ctgacagagc aaagtgaaat ggacaagcgg ttgtatttta acaaattaag caaaatagtt
    16741 atttgataga aagagagagt agtatgattc ctttagaaat taaatataaa aaggcgatta
    16801 tcttcaaatc gccttttggg taatgcagtg taattttatt cagttatttg aaatatagtt
    16861 tcattcggtt tagaaaatcc atacaatttc cttgcgaatt ttaaaatttc ttcttcacta
    16921 cttgttaaag ctttaacatc attcttaagg gaatgaccat ccttctttac agaagataat
    16981 ttttgttgtt ccgtattcag cgtgatttgt ttttctttaa tcatttcttg ttggttattc
    17041 agagaatatt gaaggacaaa aattataggt accataatag ccaaagtagt tataatacgg
    17101 cgtcttgttt tttttctatt accttgttgt gtattagggt tcacttgctg tgagggtata
    17161 ttaggatttg attggtgtga tgatactttt gggatgtttc ccattaaaat gcctccatta
    17221 ctgattgtag aatttaaacc gtttaaaagt attataaatg tttaatggga attttagaag
    17281 atattttaat atagttgcat atcgtaaagt ttaaacaaaa tccttattta cataaaagaa
    17341 acaccgattg tctgcgaggc tcctaaggat aatcatcaag taatgaagta ctcgactaat
    17401 taacgatatc acgaattttt gggtaaaaac attgaaaaat ccgtttaaat taataggagt
    17461 attatttgaa ataaaaacgc tattttaata cggaagggaa taatgatgat tccatgggat
    17521 aagcgagtat acattgtatc aaggtgatca ttttattaca gaggggacaa ttgtagaggt
    17581 tagtgaaaag gcaaataaat cattatattg gctccagtgc atgatagatc caagttatga
    17641 aaaagtgtgc gggaatagta caaagcgact tcggttgatt cggatagata atgacgaaga
    17701 atgagatgat taaggatagg tattgaatat gccatatttg tatgaataaa gagcagaata
    17761 tagccaatat ataggtgttg aaattgttct aaaggtagga atatctgaaa tataaataat
    17821 tgaggggagt gaactaaaaa tggaaactag cactttttta ggattgtttt ggggatggat
    17881 cacggttatc gtatcgggaa tacttttcgt acgcccatcg gtattacgtg aattgaaaaa
    17941 attagtggct gaagacagag ggtttggtat tatgtacggt tttttatcga ttttccttgg
    18001 gctaggcact gtaatcctac ataatgtatg ggcattcaac tggcaggggt tcctaacggt
    18061 tattgcatgg cttgcattat taaagggaat ttacataatt gcatatcctg aaccctccaa
    18121 gaaaactgat tttgaattaa ggatactaac tacacgtata gcgctcgcta tcattggcgc
    18181 tttggcttta tggatgctta tagtaatcta tataaaataa tcttttttaa tgagaaatat
    18241 actaaaatat gagaaaaggc tataatacta attataaatt tagtcctact ggaagaatcc
    18301 gtggacatca aactaaaaag ggcgttatta tagtgctctg tagtttggtg tccacttttt
    18361 tatttttaat taacaaaata aatcagtggt gtttttataa atgacgcaat taacttccga
    18421 attaaaattg atcgaaaaga aaagtacgtt tgttcggaag gggtgttaaa gaaattatta
    18481 caactgtgta aggttaatgt aatattaatc gatagtaaat caagatactt aagtgtattt
    18541 ttaataggat ttgaaagtac tgtttttaac atattgggtt aaataaaatt taattaggaa
    18601 gtgtaataca atgattgaga ttaaatctat gatttattcg tacaaactaa aaagaagaat
    18661 agctaaagat ttatatggca gcagagatga gttgacgatg ttattaaatg aatttaataa
    18721 tatgaaaagt aaagtgaagt ctgacaaaaa gaaaaataat atgttatctc gtttacaatt
    18781 aatgtaccaa aatatgaaat tagacaagca gtattctctt ccgtttgctc ttaatagtag
    18841 gttattggag cgattagaag atgaatctat tcaaacaact gaagaatgtg tatcatgtct
    18901 acacgtaatg ttagaaataa attatgagaa aataaaacat tatggatcta atacaagtag
    18961 gtcatttgtt ccgttatcac agtcttccat ttgtcttgct gattttgttt gtttgacagg
    19021 atttgtttta ttaggcttac taggaacaat tacatttgga gggataatgt aatcttttta
    19081 ttcacttaca taaaagacca cccatttaag gtgtattttt tagttacata gaagagctca
    19141 tgcgatagac agggaagaat gacacggatg ctaatttcta gttgctcatt gtcaatgcat
    19201 tgtgtaacta gaaagataaa atgttatgat gctaggaata acaaggaatt tagcgtttgg
    19261 gctagttaca caaaatataa gatatgggta actcatagta aacgtgaaat gataaaccct
    19321 atgttgtcgc agcgattaag tgagtatgct gagggtttgt tattgatgca aaattaagtg
    19381 ttacaggact taatgcacca tagcaaaagg aaaacttact actgtaaata aagtgtatgt
    19441 gaaataatta caaagtcgat ttataagagt cagcttatat ttcgacactc cactcaactt
    19501 gtaactatag atgccattct aaatcagtac gtgttaatat acaaaaagct gactatactc
    19561 agtcagcttt ttgtatatta tattctagta tttatcgatc ccaaaagaca tattctttcc
    19621 gttaagttga cattaaaatc ttaccaatgt tttcttttac aatgacaaca aataaagaaa
    19681 catttacaac gacacttatt tcgtttagaa ctccaatcat catcacaatg atgcttttct
    19741 ttagacttcc accaatcatc attacaatgc ttttccttag aactccaatc atcatcacaa
    19801 tgatgctttt ctttagactt ccaccaatca tcattacaat gcttttcttt agatttccac
    19861 cagtcatcac aacaatgctg tttcttagaa ctccagcaat cattattcca ggacattttt
    19921 ttatacctcc cttcaataga attactatca ttctatgttt tagtgaagaa atggcttgtt
    19981 tataaaccta ttattttatc tttatatgat agagtgcttt ctactacata tagaattcat
    20041 aaaaactatg ctaattttca agagatagtg gagagaatta ctggttatga catttatcaa
    20101 taaacacatg ttgaagaaaa cattctgatt ataaataata tctaattttg gagtacattt
    20161 ttctgaatgt atatttcaaa acagcggaga aaaaatatat tatattactg caaacaaagc
    20221 ctatgtatat gtaaagtaat agaaaaaaca gctaactctt aaaggagctg gcttattaaa
    20281 agaaaaaaag attcatttga taaagaggtt atctaaactt taaattcagc agaattaaat
    20341 ccaagtcccc tcattaaaca agccgctaac tgttaaagaa ttgtttttat aattaataaa
    20401 gaaaaaaatg tttagtacaa ttgtttgttt ttttctttct atgtgtttgc ctcgtacact
    20461 tttaagctag tggacatact ttactaatag aaaggattag ggggtgaggt tttgggttct
    20521 cgatttaata attgtaaaaa gaagtgtaca tgtaaacagg atgattgttg ggagatattc
    20581 gaagagtgta acaaagaaaa gcatgagaaa tgtgataatt cttgtgtgca aggaattaga
    20641 gatgagctta agaaattaat taatcgcaca gttcaaatta atacagaggg acgtacttat
    20701 gtaggtactg tttcgtctgt aagttgtgat gtagttaagc ttgcagctat tcctggatct
    20761 gttgcagtaa ttatctccat ttgcaaaatt gaagcaattt tccctcctgt tacaacggtt
    20821 actgcagagt ttgattttaa tggtgttgac gtagcaaata aagcataatt atgctttgtt
    20881 tgtaaagcca ttctgatgaa tggctttatt ttaatttcgt ataaaaggag aatatattct
    20941 ttatatagaa ataagtttga ggctataaag agtgatgtac gaaaggagaa tgagagtgat
    21001 taaattagtg ccctttaaaa gatctgattt caaacaatta ataaattgga ttcattccga
    21061 acaattttta atacagtggt caggaaatgc attcacatat cctttaaacg aacagcaatt
    21121 agagaaatat atagaaagtg caaatacact cgctttcaaa gtaatagatg aaaagactga
    21181 agaagtactt ggtcatattt cacttggtca aatagacgat ataaataagt ctgcgagaat
    21241 tggaaaagtg ttagttggta atacgaaaat gagagggcgt tcaataggaa aacatatgat
    21301 gaaagcagta cttcatattg cgtttgaaga attaaaacta catagagtaa ctcttggcgt
    21361 gtatgatttt aatacgtcgg ctatttcttg ttatgaaaaa ataggatttg taaaagaagg
    21421 tttattaaga gattcaaaaa aagtaggaga aacgtattgg aatttatggg aaatgagtat
    21481 gctagaatat gaatggaata ataaaaaata atagtttctt ataattttat tatgttaatt
    21541 aaaaggggtt ggtgggaaat tatgaataga aagactatag taatcacaat tgcagctgtt
    21601 tcagggggag gtaaaactac tattacagaa agtttaactc atgagttaac aaattcaaaa
    21661 gcgctatttt ttgatagtta taactttgat aactgtcctg ctgatatttg taaatggatt
    21721 gatgatggag caaattatga cgagtggata cttacaccat taattcatga tattcagcat
    21781 cttatacgag atagtaaatt agactatatt attgtagatt atccttttgc atacttaaat
    21841 agagaaatgg ggcagttcat tgatgtaact atatttattg acacaccttt agatattgca
    21901 atggctagaa gaattttacg agattttaaa gaagatacta tgagtgaaat acataatgat
    21961 ttaaaacatt acatggcaca tgcgagaaaa gcttatttag aggcaattca tactgttaaa
    22021 ccgaattcag atatcgtatt ggatggatct ttttctgtaa gtgaaataat taatcatgtt
    22081 gttgaggaac ttgaccgaag agaagtgatt gtcgatggtt aaatgtatag aggaatatgt
    22141 agaagttgat gattttaaaa tgtatacgaa agtattccaa ggaaagaagt ggcagcctgt
    22201 tattataatg gaatcaggct acggggatta ttcaaaggca tgggattata ttgctgaaag
    22261 actgacggaa tttgggacga tacttacata tgatcgagct ggattaggga aaagtgggaa
    22321 gagttccaag caacgtatta gttctgaaat ggtcaaagat ttaagaacat gtttaaatct
    22381 tttacaactg aagccacctt atatttttgt agggcattct tttggtggta taaatgcacg
    22441 gttatttacg gttttttatc ccgaggatat gttgggaaca gttttggttg attcgacacc
    22501 agaaaattat aaagaagtat ttttgccaat catgtctcca gaatttcaag aagcttacta
    22561 taaacaattt gcatatgaaa gttcatatga agagtttatg tttagtctag gtgaagcaga
    22621 tagacattgt aaatcaatga gcgatattcc ccttgtcgtg ctagctgctg gtaaaaaagc
    22681 tttttattcg caagctgcac aactgaaatg gttacaatta caaagagaat tattacaatt
    22741 atccagtaaa aataaattta taattgcaga acatagcggt cactatattc aaaaggatga
    22801 gccacattat attataggtg ctgttaagtg gatacttggg gtaggggaga gataaatgtg
    22861 tacactgtat ttcaatataa ctggcaagta agagaagatt ggtttaagtg gtgtgaacaa
    22921 cttacagtgg aagaattact tcgcaaacgt gttggtggtg ttggaagtat attagaaaca
    22981 ttatttcata ttgtagatgt tgagtatagc tggatttgtg atttgaaagg aaaagaagta
    23041 gatgagccgc aatttaagga ttatcaatct attcaaaaag tgaaagcatt atctcatttg
    23101 tataataagg atttagaggg atttttacaa tcgtggacag aagacttaga gaataaaata
    23161 ttaaaagttt catggacgga taaagagtac aagtatggtg aagtgttacg acatgttatc
    23221 gtacatgaaa ttcatcatat aggtcagcta tcaatatggg caagagagtt aaatcttcag
    23281 cccgtttcag cgaatttaat tggaagggga ttatagacgt aaaaaccgac ttgtactgta
    23341 aacgcaagtc ggtttttata tgtaagaaga tttcttagtt gaaatcctcg gattttcttt
    23401 gacgtaaatg taaaaacatt aaaattgtaa taatgaaaaa gatcatcatc gtttgtatga
    23461 ttaaattttt aaactgtagc aatattgccc aagatgtaag agtatcttta aaagcttgga
    23521 gtgcagagta cgaggaaggt tcaaaaccgt actgaagtaa tttttttgtt tcaataaaag
    23581 tagtgttttc ttcatcggat tctaatatta ctgaaataag cctagtatct cctagttttg
    23641 cagtaccgac aaaactatta ttaccgttag ttgaaaaact agtttgcaag ccatcaacac
    23701 cttggagttt aatgttttca ttgagggaat aaatcatttt atttgtgttg aaaacttgaa
    23761 aatttttgaa ggtaaattgg taagaggtta gtttcgtcat attcagtaca ttagggaaat
    23821 cttttactaa atgcgttgct agtttagctg catctttcgc tgttgtattc gattgtttat
    23881 ttgtatcttg attagctcca gtagagttta gaaaaggaga tggctgtgat aactgtagct
    23941 gttttgcttt ttcattcatt aacgttgtaa agttatcttc attgccacca atgtgttctg
    24001 ccagtgcgag tgcagaacga ttatttcctg ttaaaagcaa tgcatgaagt aaatcacgaa
    24061 ccgtcgtttt atcctttgct gttacttgca taggagtcgt ttccgcttgg aataattcgt
    24121 tacttatttt tacggattca tctaactgta ttttgccatc attcagttgt tccaatacga
    24181 tatactctgt cattaattta gacaaagtag ctgattgtat aggggtttct tcattttttt
    24241 tataaataac ttcacctgaa ttagcatcta ttaaaatagc tgatttagct tgaataattg
    24301 gaccatttac ataaagataa aaatataaaa cgataagtgc agtaataata aaagataata
    24361 ataaaattgt gaattttttc aagaattgca taagcgatcc tcctactatg acatcaataa
    24421 taatattgta aaaaggaatg cttaattagg aagaaagaaa aggtaaagaa tttctaaaga
    24481 attataaaag attattaaac tttggatatt gatggaaaat aaaaggttca atttcttatc
    24541 atattagaaa ttgaacctaa aattatggtg tattaatttt tatatggtag tagttttaca
    24601 gtgaaagttg ttttcttgtc atcactatat acttcaatcg ttcctttatg cagttcgaca
    24661 atactttttg caattgctaa tccgagtcct gatccaccag tgtttgttga acgtgatttt
    24721 tcaacacgat aaaaacgttc aaaaatatga ggtaaatctg tactaggaat aggttgtccg
    24781 taatttgtta tatcaattgt aatcatatta ttgctttcat aagcggtaag gtcaatataa
    24841 ccaccttcgt ttccataagc gatagcgttt ataataagat tttcaaatac acgcactaat
    24901 ttgtctccat cagctaatac catgagtttt tgagagggga aagaagggcg gcattcaata
    24961 tttgcttctt gcacttgtat tcggaattga acagttaatt gtccaagtag ctctacaata
    25021 tcaatgggag cagaatataa acttaactct ttattttgaa cacgggtgta ttcaaacaag
    25081 tcattcatta atgcatttag acgtgttact ttaccataaa tgacttgtat gtaatgacgt
    25141 aattccactt catctctata attatcatga tggattaaat tcacgtatcc aactattgat
    25201 gtaaggggag tacgtaaatc atgtgataca tttgtaatt
//
