LOCUS       c00001_NZ_JIAA..       27052 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_JIAA01000001.1 Clostridioides mangenotii LM2
            P160DRAFT_scf7180000000002_quiver_dupTrim_16548.1_C, whole genome
            shotgun sequence.
ACCESSION   NZ_JIAA01000001
VERSION     NZ_JIAA01000001
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:46:41
            Original ID  :: NZ_JIAA01000001.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2955541
            Orig. end    :: 2982593
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..27052
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[2965541:2972593]"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..17052
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..27052
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..27052
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="7"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             complement(33..959)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123:polyprenol-monophosphomannose synthase ppm1
                     (Score: 116.7; E-value: 2.4e-35)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2789"
                     /sec_met_domain="Glycos_transf_2 (E-value: 3.9e-19,
                     bitscore: 66.6, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKIAVLVPCYNEEMTIKSVIADFKNVMPDADIYVYDNNSKDKTT
                     EIAKKEGAIVVREYRQGKGNVVRSMFRDIEADVYIMVDGDDTYPAKDAYNVAKLVMEGK
                     ADMAIGDRLSSTYFTENKRPFHNTGNKLVRALINKIFKSNIKDIMTGCRAFNRKFVKSF
                     PVLSKGFEIETEMSIHALDKRFLIGEVEIDYRDRPDGSESKLNTFRDGFRVLKTILNLY
                     KDYKPLSFFGGISLILFIIGVLAFAPVFLGFIKTGQVAKFPTLIVSIGLMTSSLVSLAC
                     GLILDTVKKHSDQFYELAINLLEKGNK"
     PFAM_domain     complement(477..944)
                     /aSDomain="Glycos_transf_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00535.28"
                     /description="Glycosyl transferase family 2"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2789_0174"
                     /evalue="7.50E-17"
                     /label="ctg1_2789"
                     /locus_tag="ctg1_2789"
                     /protein_end="161"
                     /protein_start="5"
                     /score="61.8"
                     /tool="antismash"
                     /translation="VLVPCYNEEMTIKSVIADFKNVMPDADIYVYDNNSKDKTTEIAKK
                     EGAIVVREYRQGKGNVVRSMFRDIEADVYIMVDGDDTYPAKDAYNVAKLVMEGKADMAI
                     GDRLSSTYFTENKRPFHNTGNKLVRALINKIFKSNIKDIMTGCRAFNRKFVK"
     CDS             complement(976..1392)
                     /locus_tag="ctg1_2790"
                     /transl_table=11
                     /translation="MEMFQKYRETILYLVFGVLSTLINIGTYAFCTRVLGINYYISNII
                     AWLVAVIFAYITNKFYVFESKSIEYKYVIKELLSFMSCRVLSGVIELILMFVMLNLLLI
                     NDFIVKIITNIVVVILNFIFSKLIVFKNEKIEKI"
     PFAM_domain     complement(1003..1356)
                     /aSDomain="GtrA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04138.16"
                     /description="GtrA-like protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2790_0175"
                     /evalue="5.10E-22"
                     /label="ctg1_2790"
                     /locus_tag="ctg1_2790"
                     /protein_end="130"
                     /protein_start="12"
                     /score="78.4"
                     /tool="antismash"
                     /translation="YLVFGVLSTLINIGTYAFCTRVLGINYYISNIIAWLVAVIFAYIT
                     NKFYVFESKSIEYKYVIKELLSFMSCRVLSGVIELILMFVMLNLLLINDFIVKIITNIV
                     VVILNFIFSKLIVF"
     CDS             complement(2037..2705)
                     /locus_tag="ctg1_2791"
                     /transl_table=11
                     /translation="MNILDAIEIRHSVRSYTDQNIDREIQGKLQEVIDQCNIEGDMNIQ
                     LCIDEPNAFSGLMASYGKFKNVKNYIAIVAKKGNNFEERCGYFGEKVVLKATQLGLNTC
                     WVAATYNKGKTNYKINPGEKLCCVIALGYGTTSGVNRKTKSIEQLCSVDGEMPDWLKNG
                     MKSVQLAPTAMNQQKFLFELNGNIVTVKALLGFYTKLDLGIVKYHFEVGAGTQGWKWSE
                     "
     PFAM_domain     complement(2067..2702)
                     /aSDomain="TM1586_NiRdase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14512.8"
                     /description="Putative TM nitroreductase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2791_0176"
                     /evalue="8.90E-78"
                     /label="ctg1_2791"
                     /locus_tag="ctg1_2791"
                     /protein_end="213"
                     /protein_start="1"
                     /score="260.9"
                     /tool="antismash"
                     /translation="NILDAIEIRHSVRSYTDQNIDREIQGKLQEVIDQCNIEGDMNIQL
                     CIDEPNAFSGLMASYGKFKNVKNYIAIVAKKGNNFEERCGYFGEKVVLKATQLGLNTCW
                     VAATYNKGKTNYKINPGEKLCCVIALGYGTTSGVNRKTKSIEQLCSVDGEMPDWLKNGM
                     KSVQLAPTAMNQQKFLFELNGNIVTVKALLGFYTKLDLGIVKYHFEVGA"
     CDS             complement(2873..3166)
                     /gene_functions="regulatory (smcogs) SMCOG1058:ArsR family
                     transcriptional regulator (Score: 55; E-value: 9.6e-17)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_2792"
                     /transl_table=11
                     /translation="MDINQMAKVFKALSNENRLELYLKILESKETSYVDNRVCECFVTD
                     LIKSFKIGAPTISHHIKELVNAQLITTEKRGKFLICKVNEDLLQDVKKMLSL"
     PFAM_domain     complement(2954..3049)
                     /aSDomain="HTH_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01022.22"
                     /description="Bacterial regulatory protein, arsR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2792_0177"
                     /evalue="1.20E-05"
                     /label="ctg1_2792"
                     /locus_tag="ctg1_2792"
                     /protein_end="71"
                     /protein_start="39"
                     /score="25.2"
                     /tool="antismash"
                     /translation="ECFVTDLIKSFKIGAPTISHHIKELVNAQLIT"
     CDS             complement(3359..3859)
                     /locus_tag="ctg1_2793"
                     /transl_table=11
                     /translation="VKMLDEILTEHIKDKFSDTPELGDKIIQTYIKLIDETLLLKRSNT
                     PVNSGESVELAKLWWQMISDFTGGNMDLLPNLMKFNNYISSWNYEVSKRVESKIGFKIH
                     IGIYFIFSVISVALLLINSFKFEYIVPVLGWGLGIVFHAIYLNFNFNSEKEVQKEIRKL
                     RGN"
     PFAM_domain     complement(3380..3586)
                     /aSDomain="2TM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13239.8"
                     /description="2TM domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2793_0178"
                     /evalue="1.10E-10"
                     /label="ctg1_2793"
                     /locus_tag="ctg1_2793"
                     /protein_end="160"
                     /protein_start="91"
                     /score="41.7"
                     /tool="antismash"
                     /translation="SKRVESKIGFKIHIGIYFIFSVISVALLLINSFKFEYIVPVLGWG
                     LGIVFHAIYLNFNFNSEKEVQKEI"
     CDS             complement(3856..4086)
                     /locus_tag="ctg1_2794"
                     /transl_table=11
                     /translation="LGDIKNQILPLNTPNEVVNALEHQKKIIEEQIENLNEALESINSL
                     HSEVLNIKKVDFKKYAEIIELLRLSNENYWV"
     CDS             complement(4538..4957)
                     /locus_tag="ctg1_2795"
                     /transl_table=11
                     /translation="MNKLLQLFYKYKEVLLYLFFGVLTTIVSFVSFYISSEILEIHYLI
                     SNVISWIFAVGFAYVTNRIWVFESKTKEIKTILKEIFTFVNCRLLSGIIDMITMFILVD
                     IFITDNIYAKIFTQVIVVILNYIFSKLIVFKDNNY"
     PFAM_domain     complement(4556..4909)
                     /aSDomain="GtrA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04138.16"
                     /description="GtrA-like protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2795_0179"
                     /evalue="1.80E-24"
                     /label="ctg1_2795"
                     /locus_tag="ctg1_2795"
                     /protein_end="134"
                     /protein_start="16"
                     /score="86.3"
                     /tool="antismash"
                     /translation="YLFFGVLTTIVSFVSFYISSEILEIHYLISNVISWIFAVGFAYVT
                     NRIWVFESKTKEIKTILKEIFTFVNCRLLSGIIDMITMFILVDIFITDNIYAKIFTQVI
                     VVILNYIFSKLIVF"
     CDS             complement(5048..5974)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123:polyprenol-monophosphomannose synthase ppm1
                     (Score: 160.4; E-value: 1.2e-48)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2796"
                     /sec_met_domain="Glycos_transf_2 (E-value: 2.3e-29,
                     bitscore: 99.9, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKLSVIIPAYNEEKMIFNISKIISSLLENENIPYELIFVNDGSK
                     DDTWEKILYVCNQNKNIKGFNFSRNFGKEAAIFAGLTYANGDCCAVIDCDLQHPPETLL
                     EMYKKWQEGYEVVEGVKASRGKESFLHKVAAKRFYSFISSATKIDMSRASDFKLLDRRA
                     VNILRSMPEKHIFFRALSSWVGFKTTSVEFHVQERNAGDSKWTTSALIKYAITNITSFS
                     TAPMQLVTFTGILFLFFSIILGVQSLYKYFSGQSLEGFTTVVLLLLIVGSVIMLSLGII
                     GYYIAKIYEETKNRPRYIVSEYKNYIN"
     PFAM_domain     complement(5591..5962)
                     /aSDomain="Glycos_transf_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00535.28"
                     /description="Glycosyl transferase family 2"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2796_0180"
                     /evalue="2.00E-28"
                     /label="ctg1_2796"
                     /locus_tag="ctg1_2796"
                     /protein_end="128"
                     /protein_start="4"
                     /score="99.4"
                     /tool="antismash"
                     /translation="SVIIPAYNEEKMIFNISKIISSLLENENIPYELIFVNDGSKDDTW
                     EKILYVCNQNKNIKGFNFSRNFGKEAAIFAGLTYANGDCCAVIDCDLQHPPETLLEMYK
                     KWQEGYEVVEGVKASRGKES"
     CDS             complement(6517..6726)
                     /locus_tag="ctg1_2797"
                     /transl_table=11
                     /translation="MINKYREIIVYVFIGGCTTLVNLITYTAMYKLLDIDINISNITSI
                     VVAIVFAYFANKIVVFRWIIHLKL"
     PFAM_domain     complement(6541..6696)
                     /aSDomain="GtrA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04138.16"
                     /description="GtrA-like protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2797_0181"
                     /evalue="1.10E-10"
                     /label="ctg1_2797"
                     /locus_tag="ctg1_2797"
                     /protein_end="62"
                     /protein_start="10"
                     /score="41.8"
                     /tool="antismash"
                     /translation="YVFIGGCTTLVNLITYTAMYKLLDIDINISNITSIVVAIVFAYFA
                     NKIVVFR"
     CDS             complement(6743..8329)
                     /locus_tag="ctg1_2798"
                     /transl_table=11
                     /translation="MEGKFNYQFKGFIKDRNVIYCFLSSIFFGLLSYSYFFTNNLNNYD
                     NISSTPAGYGTGASSGRWFLSVFGDFVEQHWGNYNIPFFNGLLLILILGASSCILIRMF
                     KVKNKWLCALIGAITVVFPPIASAMIFSYTIGYYAIAIFFVAFGIFMIKDFKFIGFILG
                     VLLFSFSLGIYQAYYPLCASIFLLLLIKMCLDSETTGKQIVLTGIKFLLSLAIGYLLYK
                     LFLEYHLHANNVGLSSYKGVDQMGKVDISLLPMQIVVILKSVLKLTFKDYLSISGTKIV
                     QHSFLVMYIINCIAIILHIKNQKFNKGLAFKLLLMAIFILLLPIAMNFIVVMVPNGYVY
                     TIMQMGFVCLFYLTIILVDHVCGDELLDNKINIPKKFQLNKVVLFSTITVILIATLNYS
                     WQTNGNYRSLYYANRQLENYYQTLFTRIKSTENYNQDMDIYFVGEDIDDRTFRNFKWEY
                     TPFQYGGNSSPLNTYSRSATIANYLGYSFIKIEKDSEEYEKHKNDILEMDLYPNYNSIK
                     IVENKIFVRFE"
     PFAM_domain     complement(7280..8227)
                     /aSDomain="Glucos_trans_II"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14264.8"
                     /description="Glucosyl transferase GtrII"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2798_0182"
                     /evalue="7.40E-44"
                     /label="ctg1_2798"
                     /locus_tag="ctg1_2798"
                     /protein_end="350"
                     /protein_start="34"
                     /score="150.4"
                     /tool="antismash"
                     /translation="YFFTNNLNNYDNISSTPAGYGTGASSGRWFLSVFGDFVEQHWGNY
                     NIPFFNGLLLILILGASSCILIRMFKVKNKWLCALIGAITVVFPPIASAMIFSYTIGYY
                     AIAIFFVAFGIFMIKDFKFIGFILGVLLFSFSLGIYQAYYPLCASIFLLLLIKMCLDSE
                     TTGKQIVLTGIKFLLSLAIGYLLYKLFLEYHLHANNVGLSSYKGVDQMGKVDISLLPMQ
                     IVVILKSVLKLTFKDYLSISGTKIVQHSFLVMYIINCIAIILHIKNQKFNKGLAFKLLL
                     MAIFILLLPIAMNFIVVMVPNGYVYTIMQMGFVCL"
     CDS             complement(9033..9359)
                     /locus_tag="ctg1_2799"
                     /transl_table=11
                     /translation="MMSKVVGFLRDVVIAYVYGAGAISDAYLMSLNIITVAFIGLLCVA
                     IQSTYMPIYTTIERKSGRSNALLFTSNIINIIMAISLLVVILGWFFTEPLVKLFAIGFE
                     GYTL"
     PFAM_domain     complement(9045..9320)
                     /aSDomain="MurJ"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03023.16"
                     /description="Lipid II flippase MurJ"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2799_0183"
                     /evalue="7.50E-10"
                     /label="ctg1_2799"
                     /locus_tag="ctg1_2799"
                     /protein_end="105"
                     /protein_start="13"
                     /score="38.1"
                     /tool="antismash"
                     /translation="IAYVYGAGAISDAYLMSLNIITVAFIGLLCVAIQSTYMPIYTTIE
                     RKSGRSNALLFTSNIINIIMAISLLVVILGWFFTEPLVKLFAIGFEG"
     CDS             complement(10001..10153)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2800"
                     /sec_met_domain="TIGR04223 (E-value: 1.1e-08, bitscore:
                     32.5, seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKDVMSTLLEGVGSLAMSTLKLSANSTSAVLSHQPKLPKNLNQF
                     KKKSK"
     aSDomain        complement(10028..10129)
                     /aSDomain="TIGR04223"
                     /aSTool="tigrfam"
                     /description="quorum_AgrD: cyclic lactone autoinducer
                     peptide"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2800_0053"
                     /evalue="1.60E-08"
                     /identifier="TIGR04223"
                     /label="ctg1_2800"
                     /locus_tag="ctg1_2800"
                     /protein_end="42"
                     /protein_start="8"
                     /score="32.5"
                     /tool="antismash"
                     /translation="LLEGVGSLAMSTLKLSANSTSAVLSHQPKLPKNL"
     CDS             complement(10150..10737)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2801"
                     /sec_met_domain="AgrB (E-value: 4.2e-40, bitscore: 134.5,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVELCANKITLYLIKKETIDADDYELYQYAFETIVALIMQLSTIL
                     IIGFSLNRFTETLLFLVFYCPIRQFSGGFHAENYKRCLLFFVTIYITNIYLMNKLISMK
                     STTAVIVLAFISFIGIYFLAPQEHRHNPLSSEEIKKYKKIVMYLCSFLLIISVIGINFV
                     LTYEYAMYLSSVIVWIFIMLILGLIKKGVTNL"
     PFAM_domain     complement(10192..10722)
                     /aSDomain="AgrB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04647.17"
                     /description="Accessory gene regulator B"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2801_0184"
                     /evalue="2.50E-39"
                     /label="ctg1_2801"
                     /locus_tag="ctg1_2801"
                     /protein_end="182"
                     /protein_start="5"
                     /score="134.6"
                     /tool="antismash"
                     /translation="ANKITLYLIKKETIDADDYELYQYAFETIVALIMQLSTILIIGFS
                     LNRFTETLLFLVFYCPIRQFSGGFHAENYKRCLLFFVTIYITNIYLMNKLISMKSTTAV
                     IVLAFISFIGIYFLAPQEHRHNPLSSEEIKKYKKIVMYLCSFLLIISVIGINFVLTYEY
                     AMYLSSVIVWIFIM"
     CDS             complement(10761..11984)
                     /locus_tag="ctg1_2802"
                     /transl_table=11
                     /translation="MLESSIYWSTLLVITTIIEFSVFRFILGNISNLIKSKKIVNLCVA
                     GAIFISVYMTSNNFMSDFKIIILIFMTFALYKFNYETSIGKSIVVSVIFWLMITGIDLM
                     GSSIVVILNSIDNMNLLLENNAYRLEFIILTKSILLLIIPIVKGIKLSFEISKKEYFLV
                     SIPIFTNLLVVGVIIYFLFDESVTVNYDIKIMILIISIILLISNISILFIISKIVKANE
                     LRHVNKLMKVKIGFQQKYYVGLQKAQLGIKTLYDTQNNILDIILTEKKSICDNNNIKLI
                     VNIDFSICDFIETADICNIFSNMVEHSIESCNKVKGKSIHKKIKISGKVVNNFFVIKCV
                     NTIDHLKLVNNTNTDEIDFYEDVGMNSIKLSLKKYSGEVVITSEKELVKTILLPLVKNC
                     TDFKPETN"
     PFAM_domain     complement(10815..11108)
                     /aSDomain="HATPase_c_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14501.8"
                     /description="GHKL domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2802_0185"
                     /evalue="9.20E-12"
                     /label="ctg1_2802"
                     /locus_tag="ctg1_2802"
                     /protein_end="390"
                     /protein_start="292"
                     /score="44.8"
                     /tool="antismash"
                     /translation="ETADICNIFSNMVEHSIESCNKVKGKSIHKKIKISGKVVNNFFVI
                     KCVNTIDHLKLVNNTNTDEIDFYEDVGMNSIKLSLKKYSGEVVITSEKELVKT"
     CDS             complement(12459..13280)
                     /gene_functions="regulatory (smcogs)
                     SMCOG1171:transcriptional regulator, MerR family (Score:
                     64.5; E-value: 2.8e-19)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_2803"
                     /transl_table=11
                     /translation="MDKNKKMYFSTGEFARLCNVNKKTLFHYDNIDLFKPERVLSNGYR
                     YYSHYQLELFNVIYTLKTIGMSLIDIKSFINKRDAQSVIELFEYQTKEVEKEIKILKRI
                     QKIISNKVNIINDAMSYTSEIRLEEQKREYLILSEPIDITKRIYDIDNYVSHLNYINKN
                     HLNYGYPVGAIITKDDLKKEIYDVYSYYFTNIDKKTSDSKIFVKPKGMYVVGYSKGYYD
                     KTPFIYYRLMEYIRANDLSVIGNSYEQILLDEVVSKNMDDYIIKVCIHVEQ"
     PFAM_domain     complement(13053..13256)
                     /aSDomain="MerR_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13411.8"
                     /description="MerR HTH family regulatory protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2803_0186"
                     /evalue="6.00E-14"
                     /label="ctg1_2803"
                     /locus_tag="ctg1_2803"
                     /protein_end="76"
                     /protein_start="8"
                     /score="52.0"
                     /tool="antismash"
                     /translation="FSTGEFARLCNVNKKTLFHYDNIDLFKPERVLSNGYRYYSHYQLE
                     LFNVIYTLKTIGMSLIDIKSFIN"
     CDS             13357..14700
                     /gene_functions="transport (smcogs) SMCOG1086:MATE efflux
                     family protein (Score: 263.1; E-value: 6.9e-80)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_2804"
                     /transl_table=11
                     /translation="MHNTLDKRVSLTSLLKLTLPTIIMMVSFSLYTVIDGVFVARYINS
                     EALSSINITMPIINILLGIGVMFATGGSAIVAKYMGENKILKARESFSLITISALALSC
                     LIGIVCIIFIKDIIKILGTTDLMYNYSYSYLLIMLVFTPFLILKIYFDYFLVTGGAPML
                     GLISSVAGGIINIVLDYLFIVKFNMGISGAAFATCIGYVIPSLIGISFFIKKSNIIHFV
                     KPKFSFDIIKDCCLNGSSEMISQLSSSVTTFLYNIIMISYLGEDGVASITIILYIQILL
                     NSACLGFTSGVSPRISYNYGSKDAEQVRNLVKYSYIIILIFALISFLICRSASHILVAI
                     FVNPGSNIFNITLEGFNIFSLGFLMSGINIFTSGMFTAFSNGKISAMISSVRTLISFVI
                     GIVILPKILGITGVWYVVPFAELTTLILCIFQIIKYRSKYMYGNIFVS"
     PFAM_domain     13414..13899
                     /aSDomain="MatE"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01554.20"
                     /description="MatE"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2804_0187"
                     /evalue="2.10E-24"
                     /label="ctg1_2804"
                     /locus_tag="ctg1_2804"
                     /protein_end="181"
                     /protein_start="19"
                     /score="86.1"
                     /tool="antismash"
                     /translation="PTIIMMVSFSLYTVIDGVFVARYINSEALSSINITMPIINILLGI
                     GVMFATGGSAIVAKYMGENKILKARESFSLITISALALSCLIGIVCIIFIKDIIKILGT
                     TDLMYNYSYSYLLIMLVFTPFLILKIYFDYFLVTGGAPMLGLISSVAGGIINIVLDYL"
     PFAM_domain     14086..14559
                     /aSDomain="MatE"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01554.20"
                     /description="MatE"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2804_0188"
                     /evalue="1.70E-12"
                     /label="ctg1_2804"
                     /locus_tag="ctg1_2804"
                     /protein_end="401"
                     /protein_start="243"
                     /score="47.4"
                     /tool="antismash"
                     /translation="SQLSSSVTTFLYNIIMISYLGEDGVASITIILYIQILLNSACLGF
                     TSGVSPRISYNYGSKDAEQVRNLVKYSYIIILIFALISFLICRSASHILVAIFVNPGSN
                     IFNITLEGFNIFSLGFLMSGINIFTSGMFTAFSNGKISAMISSVRTLISFVIGI"
     CDS             complement(14835..15173)
                     /gene_functions="regulatory (smcogs)
                     SMCOG1167:transcriptional regulator (Score: 98.6; E-value:
                     2e-30)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_2805"
                     /transl_table=11
                     /translation="MTNGNNPLVNNKIEDTNFGYTLKLIGGKYKMEIMFCLSKYKIMRY
                     GELKRQIESISHKTLSNALKELEADLIINRKEYPQVPPKVEYSLSERGISLMPILDYMC
                     DWGKNNRI"
     PFAM_domain     complement(14844..15104)
                     /aSDomain="HxlR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01638.19"
                     /description="HxlR-like helix-turn-helix"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2805_0189"
                     /evalue="6.70E-29"
                     /label="ctg1_2805"
                     /locus_tag="ctg1_2805"
                     /protein_end="110"
                     /protein_start="23"
                     /score="99.7"
                     /tool="antismash"
                     /translation="LIGGKYKMEIMFCLSKYKIMRYGELKRQIESISHKTLSNALKELE
                     ADLIINRKEYPQVPPKVEYSLSERGISLMPILDYMCDWGKNN"
     CDS             15292..15810
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00881"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1159:dihydropteridine reductase (Score: 50.3; E-value:
                     3.5e-15)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2806"
                     /sec_met_domain="PF00881 (E-value: 2.2e-15, bitscore: 54.5,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDFLELAKKRYSVREFTDRPVEKEKIYAILEAARIAPTAANNQPQ
                     RILVIESKEAIEKLDDCTTCRFNAPLAFLVCYDKTKTWARHYDGHNSGDVDSSIVGTHI
                     MMEAEDLGLGSVWVMSFDPEKIKQTYNLPEEFEPVAIFSVGCADEKSKPGKMHFDKKSL
                     EETTFYNRF"
     PFAM_domain     15313..15474
                     /aSDomain="Nitroreductase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00881.26"
                     /description="Nitroreductase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2806_0190"
                     /evalue="2.40E-14"
                     /label="ctg1_2806"
                     /locus_tag="ctg1_2806"
                     /protein_end="61"
                     /protein_start="7"
                     /score="53.8"
                     /tool="antismash"
                     /translation="KKRYSVREFTDRPVEKEKIYAILEAARIAPTAANNQPQRILVIES
                     KEAIEKLDD"
     PFAM_domain     15496..15726
                     /aSDomain="Nitroreductase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00881.26"
                     /description="Nitroreductase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2806_0191"
                     /evalue="2.70E-08"
                     /label="ctg1_2806"
                     /locus_tag="ctg1_2806"
                     /protein_end="145"
                     /protein_start="68"
                     /score="34.2"
                     /tool="antismash"
                     /translation="APLAFLVCYDKTKTWARHYDGHNSGDVDSSIVGTHIMMEAEDLGL
                     GSVWVMSFDPEKIKQTYNLPEEFEPVAIFSVG"
     CDS             complement(16322..16468)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2807"
                     /sec_met_domain="TIGR04223 (E-value: 9.3e-07, bitscore:
                     26.3, seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKDITSTVLEKVGSLAVSAIKLSANSTCTFLNHQAKMPQDIKNF
                     KKK"
     aSDomain        complement(16340..16444)
                     /aSDomain="TIGR04223"
                     /aSTool="tigrfam"
                     /description="quorum_AgrD: cyclic lactone autoinducer
                     peptide"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2807_0054"
                     /evalue="1.40E-06"
                     /identifier="TIGR04223"
                     /label="ctg1_2807"
                     /locus_tag="ctg1_2807"
                     /protein_end="43"
                     /protein_start="8"
                     /score="26.3"
                     /tool="antismash"
                     /translation="VLEKVGSLAVSAIKLSANSTCTFLNHQAKMPQDIK"
     CDS             complement(16465..17052)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2808"
                     /sec_met_domain="AgrB (E-value: 2.5e-39, bitscore: 132.0,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKSCANKITSLLIAKKTIEYEDYDIYSFGFETLIASIGNIIIIL
                     TIGTMLNRFIETLLFLVFYCSIRQFAGGFHAENYKRCLFCFITMYLTNIYVLDKLINSN
                     STTLVVVIAFVSYMGILFLVPQEHRHNPLSSKERKKYKKIVIYLCSILLVISAICFNFT
                     ITYEYAMYLSSVIVCIFIMLILGLIKKGVTNL"
     PFAM_domain     complement(16504..17037)
                     /aSDomain="AgrB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04647.17"
                     /description="Accessory gene regulator B"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2808_0192"
                     /evalue="9.70E-39"
                     /label="ctg1_2808"
                     /locus_tag="ctg1_2808"
                     /protein_end="183"
                     /protein_start="5"
                     /score="132.7"
                     /tool="antismash"
                     /translation="ANKITSLLIAKKTIEYEDYDIYSFGFETLIASIGNIIIILTIGTM
                     LNRFIETLLFLVFYCSIRQFAGGFHAENYKRCLFCFITMYLTNIYVLDKLINSNSTTLV
                     VVIAFVSYMGILFLVPQEHRHNPLSSKERKKYKKIVIYLCSILLVISAICFNFTITYEY
                     AMYLSSVIVCIFIML"
     CDS             complement(17087..18319)
                     /locus_tag="ctg1_2809"
                     /transl_table=11
                     /translation="LLDSNLFWLLMTLIAGVIEWYVLKYIFDEASEAKRSILVSNLLFL
                     APICVLFLMTVIEVNPILKLLIGIAMAFTIYKSNYKVTILKCVFITLFYFMLLAGVDTI
                     AGSLVILINRVPSMDVLLGDNVLRLENIIMAKSLLLILIPIIKGIKLRIEISKREYIYI
                     SIPIIANIISIVTIISLLFSISAISYSQSIIAFSASCVLLLSNASLILIVSNIVKRNDS
                     RIENEIIKEKTELQYKHYLCLQKKQINTFYDTHNLFLDVLLNEKKFICDESIIDFNVDV
                     DFSKCDFMETADVCCIYSNMIDNSIEACKNIRNNSMIKRIDISGKVVNKFHVIKCKNPK
                     TNKLILKNKILTDKQEPLASLPFGIGINSIIKSVEKYKGEVVLDLTEDDFEMTILIPLV
                     RNRFKVIGSLN"
     PFAM_domain     complement(17129..17455)
                     /aSDomain="HATPase_c_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14501.8"
                     /description="GHKL domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2809_0193"
                     /evalue="3.30E-15"
                     /label="ctg1_2809"
                     /locus_tag="ctg1_2809"
                     /protein_end="397"
                     /protein_start="288"
                     /score="55.9"
                     /tool="antismash"
                     /translation="METADVCCIYSNMIDNSIEACKNIRNNSMIKRIDISGKVVNKFHV
                     IKCKNPKTNKLILKNKILTDKQEPLASLPFGIGINSIIKSVEKYKGEVVLDLTEDDFEM
                     TILIP"
     CDS             18739..19119
                     /locus_tag="ctg1_2810"
                     /transl_table=11
                     /translation="MFNKDYENAKECLKRIYKPSQNSDLILPSIFILQKKFDEGRKQLQ
                     HSLKNSLAEATSFSWQLGTSYLNKDNLDIDRAIDYFNMAVKIRESEGNVLNTISFSCKQ
                     NCFIMLILIFNILFTSYFLIIP"
     CDS             19482..20231
                     /locus_tag="ctg1_2811"
                     /transl_table=11
                     /translation="MKILYFTGTGNNLHVAKVIGGELYSIPKLIKENKYEFEDDKIGII
                     FPVYTLGLPKIVEEFLNKAKLESKYIFAIATYGTTPGNSDKQLLKIAKKNNFEFSYINS
                     VCMVDNYLPMFDIEKEIAKKSNEDIDKNINSIVKDIESNKIFINSNANIALRIIGSLIS
                     NDYSKLTDKFIIDSNKCIECGICENVCPVNNVKIIDKSAKYNGECQGCLACVNHCPKYA
                     IKLKKEKGTARFINPNITLKEIIESNN"
     PFAM_domain     20001..20060
                     /aSDomain="Fer4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00037.29"
                     /description="4Fe-4S binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2811_0194"
                     /evalue="5.90E-07"
                     /label="ctg1_2811"
                     /locus_tag="ctg1_2811"
                     /protein_end="193"
                     /protein_start="173"
                     /score="29.1"
                     /tool="antismash"
                     /translation="IIDSNKCIECGICENVCPVN"
     CDS             20258..20806
                     /locus_tag="ctg1_2812"
                     /transl_table=11
                     /translation="MYKVNNNPLAIQSQHMIADAFINLLQGNDYNDITITQICNEAMLS
                     RRTFYRNFKVKEDIIEFLVDKMTKDIYKGIDYGNVSMEKLLYTYFSYWKNNRDFIQIIY
                     TNNLFFYLSKKFIDYAKLYIKCDTDMKSKYKYFVNVDKYVVRYIDSTLSCILELWVEND
                     FKESVESISKLTYDLINKS"
     PFAM_domain     20312..20440
                     /aSDomain="TetR_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00440.25"
                     /description="Bacterial regulatory proteins, tetR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2812_0195"
                     /evalue="5.50E-05"
                     /label="ctg1_2812"
                     /locus_tag="ctg1_2812"
                     /protein_end="61"
                     /protein_start="18"
                     /score="23.0"
                     /tool="antismash"
                     /translation="DAFINLLQGNDYNDITITQICNEAMLSRRTFYRNFKVKEDIIE"
     PFAM_domain     20504..20800
                     /aSDomain="TetR_C_8"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14278.8"
                     /description="Transcriptional regulator C-terminal region"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2812_0196"
                     /evalue="4.10E-09"
                     /label="ctg1_2812"
                     /locus_tag="ctg1_2812"
                     /protein_end="181"
                     /protein_start="82"
                     /score="36.6"
                     /tool="antismash"
                     /translation="EKLLYTYFSYWKNNRDFIQIIYTNNLFFYLSKKFIDYAKLYIKCD
                     TDMKSKYKYFVNVDKYVVRYIDSTLSCILELWVENDFKESVESISKLTYDLINK"
     CDS             20912..21283
                     /locus_tag="ctg1_2813"
                     /transl_table=11
                     /translation="MIEVVSCLITFGYTDDPDEQENKLHNFVYSNRKPLDQQYTTEGTQ
                     PTWFMVGMKSVEKAPSAKNLRLPIFNNDNGVVTVTLPDKSLDTSSAGVEVDLGIAKLHF
                     EVGAGKGTWEWGDNAKFHI"
     PFAM_domain     20924..21235
                     /aSDomain="TM1586_NiRdase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14512.8"
                     /description="Putative TM nitroreductase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2813_0197"
                     /evalue="4.50E-15"
                     /label="ctg1_2813"
                     /locus_tag="ctg1_2813"
                     /protein_end="108"
                     /protein_start="4"
                     /score="55.9"
                     /tool="antismash"
                     /translation="VSCLITFGYTDDPDEQENKLHNFVYSNRKPLDQQYTTEGTQPTWF
                     MVGMKSVEKAPSAKNLRLPIFNNDNGVVTVTLPDKSLDTSSAGVEVDLGIAKLHFEVGA
                     "
     CDS             complement(21879..21971)
                     /locus_tag="ctg1_2814"
                     /transl_table=11
                     /translation="MSKEKISKRILTLALSLSIFSTGIFSESYR"
     CDS             complement(22148..22621)
                     /locus_tag="ctg1_2815"
                     /transl_table=11
                     /translation="MSFKLVKKYFEERNLKDRIKGFDGSCATVEEAAKTIGVEAARVAK
                     TLTLRKDEGCMMMVMAGDAVIDNKKFRQYFGMKARMLTAQEVTDMTGQTVGGVSPFAIP
                     EDIPVYIDDSVNKYDTLFPACGSPNYVVELSPDEIFQYGNALEWIDVCKETGK"
     PFAM_domain     complement(22205..22546)
                     /aSDomain="tRNA_edit"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04073.17"
                     /description="Aminoacyl-tRNA editing domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2815_0198"
                     /evalue="1.20E-25"
                     /label="ctg1_2815"
                     /locus_tag="ctg1_2815"
                     /protein_end="139"
                     /protein_start="25"
                     /score="90.0"
                     /tool="antismash"
                     /translation="CATVEEAAKTIGVEAARVAKTLTLRKDEGCMMMVMAGDAVIDNKK
                     FRQYFGMKARMLTAQEVTDMTGQTVGGVSPFAIPEDIPVYIDDSVNKYDTLFPACGSPN
                     YVVELSPDEI"
     CDS             complement(23019..23609)
                     /gene_functions="transport (smcogs)
                     SMCOG1116:Homoserine/threonine efflux protein (Score:
                     102.9; E-value: 3e-31)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_2816"
                     /transl_table=11
                     /translation="VNYSVWVSFLSYTVITALSPGPNNILALNATGSAGIKKSKNILLG
                     IYTGFTCIMVICGIFSSALLIFLPNIMNYMKYIGAVYIFWLAYHVAFSKPIETNSQADC
                     QSFSKGFILQFANVKIILWGITAFTGFIMPYYQSPLVICAFVMILSLIGNGATHIWAVA
                     GSMLGSFLRKYWKISNICMSILLLYSAIHLVLE"
     PFAM_domain     complement(23025..23567)
                     /aSDomain="LysE"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01810.20"
                     /description="LysE type translocator"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2816_0199"
                     /evalue="1.00E-14"
                     /label="ctg1_2816"
                     /locus_tag="ctg1_2816"
                     /protein_end="195"
                     /protein_start="14"
                     /score="54.5"
                     /tool="antismash"
                     /translation="ITALSPGPNNILALNATGSAGIKKSKNILLGIYTGFTCIMVICGI
                     FSSALLIFLPNIMNYMKYIGAVYIFWLAYHVAFSKPIETNSQADCQSFSKGFILQFANV
                     KIILWGITAFTGFIMPYYQSPLVICAFVMILSLIGNGATHIWAVAGSMLGSFLRKYWKI
                     SNICMSILLLYSAIHLVL"
     CDS             23881..24609
                     /gene_functions="regulatory (smcogs) SMCOG1031:LysR family
                     transcriptional regulator (Score: 70.7; E-value: 2.3e-21)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_2817"
                     /transl_table=11
                     /translation="MVVTQSGKDILPYIDTILQSVEQLENYGKNISELTGSLKVAIPET
                     LLTYKMQPVLKAFREQAPGVKLSVQTLNCYDIRDKVIDGSIDIGIHYDVGGYVPSMVIE
                     KFADFSLVLIASPILDPQFCDFKTTGQRNKICLITNDPNSIFQGILNNYLEEKKIELES
                     IMELGSIEAIKGCVASNLGVSFIPSYVAETELENGTLHEVEIDLLNKKISAVCTYHKNK
                     WISPAMELFIRLTNEHLSDV"
     PFAM_domain     23977..24597
                     /aSDomain="LysR_substrate"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03466.22"
                     /description="LysR substrate binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2817_0200"
                     /evalue="4.90E-33"
                     /label="ctg1_2817"
                     /locus_tag="ctg1_2817"
                     /protein_end="239"
                     /protein_start="32"
                     /score="114.4"
                     /tool="antismash"
                     /translation="ELTGSLKVAIPETLLTYKMQPVLKAFREQAPGVKLSVQTLNCYDI
                     RDKVIDGSIDIGIHYDVGGYVPSMVIEKFADFSLVLIASPILDPQFCDFKTTGQRNKIC
                     LITNDPNSIFQGILNNYLEEKKIELESIMELGSIEAIKGCVASNLGVSFIPSYVAETEL
                     ENGTLHEVEIDLLNKKISAVCTYHKNKWISPAMELFIRLTNEHL"
     CDS             complement(25328..26050)
                     /locus_tag="ctg1_2818"
                     /transl_table=11
                     /translation="MTKVSKRGFNENDKRWFSYKELTRLTKAQEEIEWLINREYKIEPV
                     VNFTGDRYQFSLRQRDALKRAICSEEKKLIRQSKKISIDEISEGPIYIDGFNLIITLEV
                     ALSGGILIIGSDGNIRDLAGLRGTYKIIDKTDEALNLIGEFLNKYDAKEVKFYLDSPVS
                     NSGNLKYKILDCSQNWKIKTEVKLVNNADVILEKLDRVVSSDAAIIDKCISYFNVGRSI
                     IEEYIKEANIVNLNKNLF"
     PFAM_domain     complement(25394..25801)
                     /aSDomain="DUF5616"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF18481.3"
                     /description="Domain of unknown function (DUF5616)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2818_0202"
                     /evalue="3.80E-50"
                     /label="ctg1_2818"
                     /locus_tag="ctg1_2818"
                     /protein_end="219"
                     /protein_start="83"
                     /score="169.9"
                     /tool="antismash"
                     /translation="DEISEGPIYIDGFNLIITLEVALSGGILIIGSDGNIRDLAGLRGT
                     YKIIDKTDEALNLIGEFLNKYDAKEVKFYLDSPVSNSGNLKYKILDCSQNWKIKTEVKL
                     VNNADVILEKLDRVVSSDAAIIDKCISYFNVG"
     PFAM_domain     complement(25814..25981)
                     /aSDomain="DUF434"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04256.14"
                     /description="Protein of unknown function (DUF434)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2818_0201"
                     /evalue="3.70E-18"
                     /label="ctg1_2818"
                     /locus_tag="ctg1_2818"
                     /protein_end="79"
                     /protein_start="23"
                     /score="65.0"
                     /tool="antismash"
                     /translation="RLTKAQEEIEWLINREYKIEPVVNFTGDRYQFSLRQRDALKRAIC
                     SEEKKLIRQSK"
ORIGIN
        1 aaaatattat ttaatttatc caggtccata tactatttat ttcctttctc taataagtta
       61 attgctaact catagaattg atctgaatgc ttcttaactg tatcaagtat aagtccacac
      121 gctagtgata ctaatgacga tgtcataagt ccaattgata ctatcaaagt tggaaatttg
      181 gccacttgtc ccgtttttat aaatcctaga aatacaggtg caaatgctaa tacacctatt
      241 ataaataata ttaatgatat gcctccaaaa aatgaaagtg gcttataatc tttatataaa
      301 tttaatatag tttttagtac cctgaatcca tctctaaacg tatttaattt tgattcactt
      361 ccgtctggtc tatctctata gtctatttct acttctccaa ttaagaatct tttatctagt
      421 gcatgtatac tcatttccgt ctctatttca aaacctttag ataaaactgg gaaagatttt
      481 acaaattttc tattaaatgc cctgcatcct gtcattatat cttttatatt gcttttaaat
      541 attttattta ttaaagctct aactaattta tttcctgtat tatgaaacgg tctcttattt
      601 tctgtaaaat aagtactcga tagtctatct cctatcgcca tatcagcctt accttccata
      661 acaagttttg cgacattata tgcatcctta gcaggatatg tatcgtcacc atcaaccatt
      721 atgtatacat ctgcctctat atccctaaac atgcttctca caacattacc tttgccttga
      781 cgatattccc ttacaactat agccccctct ttttttgcta tttctgtagt tttatctttt
      841 gagttattgt cgtaaacata aatatcagca tctggcatta cattcttaaa gtcagcaata
      901 accgacttta tagtcatttc ctcgttataa catggtacta atactgctat tttttccata
      961 tacttttctc tcctattaga ttttttctat cttttcattt ttgaacacaa ttaatttact
     1021 aaatataaag ttaagaatta caaccactat attagttatt atttttacta tgaaatcatt
     1081 tattagtaat aagtttagca ttacaaacat taatataagt tcgattactc ctgataatac
     1141 tctacagctc ataaatgata acaactcttt tataacatac ttatattcaa tagatttact
     1201 ttcaaaaaca taaaacttgt ttgttatata tgcaaatatt acagcaacaa gccacgctat
     1261 tatatttgaa atataataat taataccaag aacccttgtg caaaaagcat aagtccctat
     1321 attaattaat gttgaaagta ctccaaatac caaataaagt attgtttctc tatatttttg
     1381 aaacatctcc attgtacact cctaaacagt ttttacatct atgataatat agtaacactt
     1441 ctatgataat atagtaacac ttctatatac gatcttacaa gtttctaggt ttaataactt
     1501 tttgtgctta gttctatata tagttgggtt gggttgttgt catactcttc aaaaaattat
     1561 tagtaatgtc gactatttat ccatttgttg atttttagat ttgaaatata taggtaatgt
     1621 tgatactgcc ataattataa tgactagtac tattatattt tttctcttac tattatgcct
     1681 gatgtattta tctttttatc tataccaagt tcaacagctt ttttccatat ttccacttca
     1741 gttaatggaa tactaaacta taggacattt tttatattca cattggtggt taatagttgc
     1801 ttttacaggt atgatatggt cttcattttt tttcattttt tgtaaataaa taagtaaaaa
     1861 acaattagaa attagttttt ttaaaaaaat ttagagaact atagtaaaaa tgaccttaga
     1921 atcaatttat ttggatttta aaggcataaa ctttcttcta aataaaataa ctagtcccta
     1981 aagtaaaatt tagtgactag tttatgcctt aaaacttcta attaaatctt aaaaatttat
     2041 tctgaccatt tccatccttg agtacctgcg cctacttcaa agtgatattt aacaattcca
     2101 agatctaatt tagtataaaa tcctagtaaa gctttcactg ttactatatt cccatttagt
     2161 tcaaataaaa atttttgttg attcattgct gtaggtgcca attgtactga tttcatgcca
     2221 tttttaagcc aatctggcat ttcaccatca acgctacaaa gttgctctat tgatttagtt
     2281 ttacggttta caccagaagt agtaccgtaa ccaagtgcta ttacacaaca taacttctct
     2341 cctggattaa tcttataatt tgttttaccc ttgttataag tagctgcaac ccaacatgta
     2401 ttaagcccta actgtgtagc ttttaaaaca actttttctc caaaatagcc acatctttct
     2461 tcaaagttat tacctttttt agcaacaatg gcaatataat tttttacgtt tttgaatttt
     2521 ccgtaactag ccattaagcc actgaatgca ttaggttcat cgatgcataa ttgaatattc
     2581 atatctcctt ctatattgca ctgatcaatt acttcttgta atttaccttg aatttctcta
     2641 tcaatatttt gatctgtata actacgtact gaatgtcgta tttctattgc atctaatata
     2701 ttcataactt atcctccaat aactaaaaat ataatgtgtt aaatatctaa tttattttct
     2761 tttaatactt ttttgaatag aataaagttc acctttaaat cgatttgcat tcgctatatt
     2821 caatattata ttttgataac tatcgaattg ttagataatg cttaggctta gcttataagc
     2881 taagcatctt tttaacgtct tgtaataaat cttcattaac cttgcaaatt aaaaactttc
     2941 ctcttttttc agtagttatt aactgtgcat ttactagttc tttaatatga tgtgaaatag
     3001 tgggagcacc aattttaaaa gatttaatta aatctgttac aaagcattca cagacacgat
     3061 tatcaacata actagtttct ttagattcca aaatttttaa atataactct agtctatttt
     3121 cattagatag cgccttaaaa acttttgcca tttgatttat atccatttga tatctcctaa
     3181 ttgtattaat tcgataacta tcgaattaat actaacactt aattgatatt agagtcaata
     3241 aatataataa ttttatcttt ttttattagt tcataaaaac ttatttaaag agttttaata
     3301 aaaaaggcac attatttact aatgtgcctt tagcaatgct ctaaactgaa attaactact
     3361 agttacctct taactttctt atttcttttt gaacttcttt ttctgaattg aaattgaagt
     3421 tcaaatatat agcatgaaat actataccta atccccaacc caaaacagga actatgtatt
     3481 caaatttaaa actattaatt aataataatg ccactgatat aactgaaaat ataaaatata
     3541 ttcctatatg aattttaaaa cctatttttg attctactct tttagatact tcatagttcc
     3601 aactagatat ataattatta aatttcatta aatttggtag taaatccata tttccgcctg
     3661 taaagtccga aatcatttgc caccatagtt tagctaattc tacactttct ccactgttta
     3721 caggtgtatt agaccttttt aataataatg tttcatctat aagttttata taggtttgta
     3781 taatcttatc tcctagttct ggagtatctg aaaatttatc ttttatatgc tctgttaata
     3841 tttcatctag cattttcaca cccaatagtt ttcattactt aagcgtaaaa gttcaattat
     3901 ctcagcatat tttttaaaat ccactttttt tatgttaagt acctctgaat gtagagagtt
     3961 tattgattct aacgcttcat ttagattttc aatttgttct tcaattatct ttttttggtg
     4021 ctctagcgca tttacaactt cattaggtgt atttaacggt aaaatctgat ttttaatatc
     4081 acccaatgaa aaacctaaat acttaaaaga taaaatttga tgtagtttaa caatatcttt
     4141 agcagagtgt tacaaagaac aataaagagt atagcgcatt gaaataagcc gttttatcgg
     4201 gattggtaaa tatattccaa gcggggtata ccttatgaca aatactatag gctatgtaag
     4261 tagataaaat gaatatctga attttaccta ttattgattt tacaaaattt ctcttattag
     4321 attcaaaact tttttgaacg ataattatac tatataatag taagcatact atttaacaac
     4381 caattattta aaaataagaa gttagatatt tgctttacat ataaatcggc gatccccatt
     4441 actgaatagg taatttgttt atatccatca gtattattca ctgcattaga ataagatcca
     4501 ttagaaaaca tttccaatta aatgaataaa gtgaaattta ataattatta tctttaaaaa
     4561 caattagttt actaaaaata taatttaata taactacaat aacctgtgta aagatctttg
     4621 cgtatatatt atcggtaata aagatatcta caagaataaa catagttatc atatctataa
     4681 ttccagataa aagtctgcag tttacgaatg taaatatctc ttttaatatt gtctttattt
     4741 ctttagtttt gctttcaaat acccatatac gattagtaac gtatgcaaac cctacagcaa
     4801 atatccaaga tattacatta ctaataagat aatgtatttc taatatctca ctagaaatat
     4861 aaaaactcac aaagcttact atagttgtta gaactccgaa aaataaatat aataaaactt
     4921 ccttatattt ataaaatagt tgcaataatt tattcatata taattccttt tttattgaag
     4981 gttattttgt ttccttcata atttgtccaa ataatttaat agttaaattt taaattgatt
     5041 atatgatcta atttatgtaa tttttatatt cagaaacaat atatcttgga cgatttttgg
     5101 tttcttcata tatcttcgct atatagtatc ctataatacc taaacttagc ataatgacac
     5161 ttcctacaat taataataga agtactactg ttgtaaatcc ttctagcgat tgccctgaaa
     5221 aatatttata tagcgattga acacccaaaa taattgaaaa aaataaaaat aatattcctg
     5281 taaatgtgac caattgcata ggtgccgtag agaatgatgt tatatttgta attgcatatt
     5341 taatgagagc tgaagtagtc cattttgaat ctccagcatt tctttcttgt acgtgaaact
     5401 caactgatgt agtcttaaac ccaacccaag aagataaagc tctaaaaaat atatgctttt
     5461 caggcataga tctgagtata tttacagctc ttctatctaa taatttaaaa tctgaagctc
     5521 ttgacatatc aattttagtt gccgagctaa taaatgaata gaaacgttta gcagccactt
     5581 tatgtaaaaa agattcttta cctcttgaag cctttacacc ttctacaact tcatatcctt
     5641 cttgccattt cttatacatt tccaataatg tttcaggtgg atgctgaagg tcacaatcta
     5701 ttactgcaca acaatcccca tttgcatatg taagaccagc aaaaatagcg gcttctttac
     5761 caaagtttcg agaaaagtta aaacctttaa tatttttatt ttgattgcaa acatatagaa
     5821 ttttttccca tgtgtcatcc ttagaaccat catttacaaa aattaattca tatggaatat
     5881 tttcgttttc caaaagagaa gatattattt ttgagatatt aaatatcatt ttctcttcat
     5941 tataggctgg tattattacc gataattttc ccatactatt tctcctttaa ttttattagc
     6001 aagataaaat tcgagtattt tacactaaat gtaacaagaa aatacctaaa cttatttcgt
     6061 taataaatta ttaccaatat tttacatttt aagtatacca tatataaaaa tgaatgactc
     6121 aaaattattt gaaagataaa aaaacaaggg gctgtctcaa aattgataac accgacttta
     6181 agacttttca tttgttcatt tgcttcttta tctattgttc ttctcaatag tgttgcatcc
     6241 atatttttga atacttcacg ttcttcgctt ctttgacaag atctacgcag gaatcacata
     6301 aatcccagat ttctatttca atataatctt tcaaactttc attgttaaaa attttcggtt
     6361 ttttgttttc aagattttcg atgcaatagt agcacctggt ttatttaaac ccgctacaca
     6421 atgcggatta ctacatgcat actaataaat aaactccata aacctcaatt atcattgtaa
     6481 atagtcttga acttataaat tttatacctt ctgaaatcag agttttaaat gaattatcca
     6541 tctaaaaaca actattttat ttgcaaagta agcaaaaact attgcaacta ctattgaagt
     6601 aatattgctt atatttatat caatatctaa taacttatac atagcagtgt aagttattaa
     6661 atttactaaa gtcgtacatc caccaataaa aacatacact ataatttctc tatatttatt
     6721 tatcattaat ttattttatc tatcattcaa atctcacaaa tattttattt tctacaattt
     6781 taattgaatt ataatttgga tataaatcca tttctaatat atcattttta tgcttttcat
     6841 attcttcact gtctttttct atttttataa aagaatatcc aagatagtta gctatagttg
     6901 cacttctaga atatgtattt aacggagaac tattacctcc atattggaaa ggcgtatatt
     6961 cccatttaaa atttctaaat gtcctatcgt caatgtcttc tccaacaaaa taaatatcca
     7021 tatcttggtt ataattttct gtagatttaa ttctcgtgaa taaagtctga taataatttt
     7081 ctaactgtct attggcataa tacaatgagc gataatttcc attagtttgc caagagtaat
     7141 taagtgtggc tatcaaaatt acagttatag tagaaaataa aacgacttta ttcaattgga
     7201 attttttagg tatattgatc ttgttatcca atagttcatc accacataca tggtccacta
     7261 agataattgt caagtagaat aaacatacaa atcccatttg cataatagta tatacataac
     7321 catttggtac catcactact ataaaattca tagctatagg taatagtagt ataaatatcg
     7381 ccattaatag aagtttaaat gctaatcctt tattaaattt ctgatttttt atatgtaata
     7441 taattgctat acaatttatt atatacataa ctaaaaatga gtgttgaact atctttgttc
     7501 cgcttatcga taaataatct ttgaaagtca attttaatac agactttaaa attaccacaa
     7561 tttgcattgg tagcaaactg atatctactt tacccatttg atctacgcct ttataggagc
     7621 taagtcctac attatttgca tgtaagtgat attctaaaaa taacttatac agtaaatatc
     7681 ctatagctaa agataataaa aacttaatcc cagttaatac tatctgttta cctgtagtct
     7741 ctgagtctaa acacattttt atcagtagca ataaaaaaat agatgcacat aaaggataat
     7801 atgcttgata tatacctaaa gagaacgaaa ataatagcac tcctaggata aacccgatga
     7861 atttaaaatc ttttatcata aaaattccaa aagcaacgaa aaatattgct attgcatagt
     7921 atccaatagt atacgagaaa atcatagcac ttgctatagg cggaaaaact accgtgatag
     7981 ctcctatcaa agcgcataac catttatttt tcaccttgaa catcctaatt aatatacaag
     8041 aacttgcccc taatataagt attaataata gtccattaaa aaaagggata ttataatttc
     8101 cccaatgttg ttctacaaaa tcaccaaata cacttaaaaa ccatcttcca ctgctagcac
     8161 ctgtcccata tccagctggc gtagacgaaa tattatcata gttatttaaa ttgttcgtaa
     8221 aaaaatacga gtatgataat aaaccgaaaa atattgaaga tagaaaacaa taaataacat
     8281 ttctatcttt aataaacccc ttaaattgat aattaaattt tccttccatt ttacctccaa
     8341 aatagctctt atttaaagca aactgttacc ctaagaacgt tgttaaattt atttatataa
     8401 ttacaaacat gtatcgacgt taactaattt ctatattgaa ttcaaagctt cttataaaat
     8461 atctttactc ttattaagtt tcccgttttt tatcttatat atatattaca ctaaaacact
     8521 gtcaattctt gtcaattttt gcttattttt aatttctttt aatttttaat agcgataaat
     8581 agtgtgtgaa ttttcactta tagtttatta gagtatttag ggcagaatgt aaaatcttcc
     8641 tccgtttcat atccacatac tgaacaaact ttttaagaag cttaactatt aaatctattc
     8701 ccatagttgc catatttaaa tattcttcat atgtcaatat gatttcaatt acgttctttt
     8761 catttttatc acttaaatct tatcttttct atcactactt gtaacatcgt cacaatgttt
     8821 ttctttagat ttttcttttt ctttattaag ctctgacctc aacgccaaat tttttactaa
     8881 gtagaataga tattattata gaaaaattat aaggtaaagg cataaagcct gttattaaga
     8941 agtaatcata tatctctaaa taggatttta gtatatacgt tacacaaact atacccagaa
     9001 aataatacta ttctagttaa ttgtacagta agctataagg tatacccctc aaaccctatt
     9061 gcaaataact ttactaatgg ttctgtgaaa aaccatccaa gtatgactac taataaagat
     9121 atcgccatta taatattaat aatattacta gtaaacagca acgcattaga gcgaccactt
     9181 tttctttcaa tagttgtata aataggcata tacgtactct gtattgctac acatagtaat
     9241 ccaataaaag ctactgttat tatatttaaa gacattaaat atgcatctga tatggcacct
     9301 gcaccataaa catatgcaat aacaacatct cttaaaaatc caacaacctt agacatcatt
     9361 gtagctagga ataaaataaa tgctgattta acatacaata aaacttaaca aatcgttaga
     9421 gatgatgtaa tcccgttatt tgccaatagt ataacatgcc ttacttatgt tctacaattt
     9481 cttaataaaa agcatgtata tattatatag taatagctta gtgccataat gttaattact
     9541 gtacaataaa taatatatta tatgtatttt cgatagttat ttaagtctct gatatttttt
     9601 attttaaaaa ataatacata aaatttacca taatatataa attaaaatgg ggttaacatt
     9661 actaattatg agcatttttg gtgaaaaact ttctgaatat aaatataaga aataagaaaa
     9721 agaacggcaa gaaagactat tactgaaaaa tagggtgttt ctagaacaac atataagcta
     9781 tctagaaaaa attctgacaa gaactactta aaatcattta gagttgagaa atctttgaca
     9841 gagaaattga gcgactatac aaaacatttg gaaaaaggag aatagaaatt ggcaaatgtg
     9901 tggtatacca gtaaattttt atagaatcaa caagattcgc ctgaatatat aaagggttgt
     9961 ctcaaaaatg attttttgtg agacagccct ttatattttt ttacttactt tttttcttaa
    10021 attgatttaa atttttcggt agttttggtt ggtgagataa taccgcagaa gtagagttag
    10081 ctgataattt aagagtactc attgccaaag aacctactcc ctctaataat gttgacatta
    10141 catctttttt cataagttag tcactccttt cttgattaga cctaaaatta acattataaa
    10201 aatccatact ataacagacg ataagtacat tgcatactca tatgttagta cgaaattaat
    10261 acctattact gaaattatta ataaaaaact acacaaatac attactattt ttttatattt
    10321 ttttatttct tcactgctta aaggattatg tctatgctcc tgcggagcaa gaaagtatat
    10381 tccaataaaa cttataaaag ctagtactat aacagctgta gttgacttca tactaattaa
    10441 cttattcatc aaatatatat tagttatata tattgtaacg aaaaatagca aacatctttt
    10501 ataattttca gcatggaatc caccagagaa ctgtctaatc gggcaataaa atactaaaaa
    10561 taaaagagtc tcagtaaatc tatttaaaga aaatcctatt attaatatag tagataactg
    10621 catgattaaa gcaactattg tttcaaaagc atactgataa agttcataat catcagcatc
    10681 aattgtttct tttttaatta aatataaagt aattttatta gcacataact caaccatttt
    10741 tccatacctc tcttatgtca ttaatttgtt tcaggcttaa aatcagtaca atttttaact
    10801 aatggtagaa gtattgtctt aaccaactct ttttcagatg ttataaccac ctcaccactg
    10861 tactttttaa gtgaaagttt aatggaattc attcctacat cttcatagaa atctatttca
    10921 tctgtatttg tgttgttaac taatttaaga tgatcaatag tgtttacgca tttaattaca
    10981 aaaaaattat taacaacttt tcccgaaatt ttaattttct tatgtatact tttacctttt
    11041 actttgttac aggattctat tgaatgttct accatattag aaaatatatt acatatatca
    11101 gctgtttcga taaaatcgca tattgagaaa tcaatattta caataagttt tatattgtta
    11161 ttatcacaaa ttgatttttt ctcagtaagg attatatcca aaatgttatt ttgagtatca
    11221 tataaagttt ttatacctaa ctgtgctttt tgtaagccta cataatattt ttgttgaaat
    11281 cctattttta ctttcattaa cttgttcaca tgtcttagct catttgcttt cactatctta
    11341 gaaattatga aaagtataga tatatttgaa attagcaaaa ttatagatat aattaatatc
    11401 attattttaa tatcataatt aactgtcact gattcatcaa ataaaaaata tataatcaca
    11461 ccaactacta ataaattggt aaaaatagga atagatacaa gaaaatattc ttttttactt
    11521 atttcaaaag ataatttaat accttttact ataggtataa ttaataataa tattgatttg
    11581 gttaaaataa taaattctaa tctgtatgcg ttgttttcta ataatagatt catattatca
    11641 attgaattca atataacaac tatactactc cccattaaat caatacctgt tatcatcaac
    11701 cagaaaataa cactaacaac tatactcttc cctatggaag tttcataatt aaatttgtat
    11761 agtgcaaagg tcataaaaat aagtattatt atcttaaagt ccgacataaa attgtttgat
    11821 gtcatataaa cagatatgaa aatggcacca gctacacaca gattcactat ctttttactt
    11881 tttattagat tactaatatt acctaagata aatctaaaga ctgaaaactc tataattgta
    11941 gtaattacca aaagagttga ccaataaata cttgattcta acatagtaga tcacccactt
    12001 ttaaattttg aataaaatat gaaaaaagtc ttttggacat acttaatccc ccctgacctc
    12061 cgagatatta ttttataagt aatttaaata aagctaattg taaaccaatg ttagttttaa
    12121 ctacattata ttatttgtaa atgctttaat atctttaata tatattattc tacatataat
    12181 ctaaaattcc tttactaatt gtcataatat gttaatatag ttagaaatta tggattctgt
    12241 tttaataaat aataaaattg agggctcact ccctcgatta actttactgt cattaactat
    12301 atctttaaag agtcataatg ttaatataag tattttttaa aacaaaataa accaattcta
    12361 aaataaattt tttccaagtt ccctatcgca gatggggaga cacattatta ttaatgtgcc
    12421 tttagctatg ttctaaactg caatttaact actagttgtt attgctcaac atgtatgcaa
    12481 acttttatta tataatcatc catattctta gaaacaactt catctaataa tatttgctca
    12541 taagagtttc ctataacact taaatcgtta gctctaatgt actccattaa tctataataa
    12601 ataaatggag ttttatcata atagccttta gaatacccaa ctacatacat ccccttaggc
    12661 ttaacaaaga tcttgctatc tgaagttttt ttatctatat ttgtaaagta atagctatat
    12721 acatcataaa tttctttttt caagtcatct ttagttatta tagcccctac tggataacca
    12781 taatttaaat gatttttatt tatataattt aaatgggaaa cataattatc aatatcataa
    12841 atacgttttg taatgtcaat aggttcactt aaaattagat attctctttt ttgctcttct
    12901 aatcttattt cactagtata actcatagca tcgtttatta tattaacttt atttgatatt
    12961 attttttgta ttcttttaag tattttaatt tctttttcta cttcttttgt ttgatattca
    13021 aataactcaa taacactttg agcatctctc ttattaataa aactctttat atctataaga
    13081 gacatcccta tagtctttaa tgtataaatc acattaaata attctaactg gtagtgagaa
    13141 taatatctat atccattgga taaaaccctt tcaggtttaa ataaatcaat attatcgtaa
    13201 tggaaaagtg tttttttgtt tacattacat aatctagcaa attcaccagt tgaaaaatac
    13261 atttttttat ttttatccat cctaaaatct ccttcttgac tatccttcta caggatactt
    13321 taacattaat tatattaaca aatcaaggag gtttttatgc ataatacatt agacaaaaga
    13381 gtttcactga catctctttt aaagcttaca ttacctacca ttattatgat ggtatctttt
    13441 tcattatata ctgttataga tggggtattc gtagctagat acatcaattc agaagcttta
    13501 tctagtataa acataacaat gcctataata aatatacttt taggaatagg tgttatgttt
    13561 gctactggag gaagtgcaat tgtagcaaaa tatatgggtg agaataaaat tttaaaggct
    13621 agagaaagct tttcgttaat aactataagt gcattagctc ttagctgcct aattggaatt
    13681 gtctgtatta tttttataaa agatataatt aaaattctag gaactacaga tttaatgtac
    13741 aactacagct attcctattt attaataatg cttgtattta ctccattttt aattttaaaa
    13801 atatactttg attatttttt agttacaggt ggtgctccaa tgttaggtct tattagttct
    13861 gtggcaggag gtattattaa tatagtttta gattatttat tcatagtaaa gtttaatatg
    13921 ggtatatctg gagcagcttt tgcaacatgt ataggatatg taattccgtc tcttataggg
    13981 atatcatttt ttattaaaaa aagtaacatc atacactttg taaaacctaa attttcattt
    14041 gatataataa aagattgttg cctaaatggt tcatctgaaa tgataagtca gttatcatca
    14101 tcagtaacta catttttata caacatcatt atgatttcat atttaggtga agatggagtt
    14161 gcttcaataa cgattatatt atatatacag attttactaa attctgcttg tcttggattt
    14221 acatcaggtg tatcccctcg tataagctac aattatggaa gtaaggatgc agagcaggtt
    14281 agaaatctag ttaaatatag ttatataata atattaattt ttgcattaat ttcattttta
    14341 atatgtagat cagcatctca tatactagta gcaatttttg ttaatccagg tagtaatata
    14401 tttaatataa ctttagaagg attcaatata ttctcattag gatttttaat gagtggaata
    14461 aatatattta ctagtggaat gtttacagca ttctcaaatg gaaaaatttc cgcaatgata
    14521 tcctcagtaa gaacactgat atcgtttgtt ataggtatag ttatacttcc taaaatacta
    14581 ggtataactg gtgtttggta tgtagttcca tttgcagaat taacaacact aatattatgt
    14641 attttccaaa taattaagta tagatcaaag tatatgtatg gaaatatatt tgtaagttaa
    14701 atcattattt gaatttagct caattagttc ttaataagtt atttaaagat atctagtgaa
    14761 aatgccctta gaatccattt atttggattt taagggcatt gcttttattc taaatacata
    14821 actagttggt tggtttaaat tctattattt ttaccccaat cacacatata atctaaaatt
    14881 ggcataagag aaatacctcg ttctgaaaga gaatattcaa ccttaggtgg aacttgagga
    14941 tattcctttc tattaattat taaatctgct tctaattctt taagagcatt acttaatgtt
    15001 ttatgagaga tactttctat ctgtcttttt aattcaccat aacgcattat tttatacttt
    15061 gataaacaaa acataatctc cattttatat ttaccaccga taagttttaa agtatatcca
    15121 aaattagtat cttcaatttt attgtttact agtggattat tgccattagt cataaattat
    15181 cactctcctt tatgttagta tataacttaa atgtaagttc tttactttag cttagtatta
    15241 gaataacata gagttaacag cagaaatcat atttatttag gaggtaaaat aatggatttt
    15301 ttagaacttg caaagaaaag atattctgta cgtgaattta ctgacagacc tgttgaaaag
    15361 gaaaagatat atgcaatatt agaggcagct agaatagctc ctacagctgc aaataatcaa
    15421 ccacaacgta tattagtaat tgaaagtaaa gaagcaattg aaaaattaga tgattgtacg
    15481 acatgtcgtt ttaatgctcc acttgctttt ttagtttgtt atgataagac taaaacttgg
    15541 gcaagacact atgatggaca taatagtgga gatgttgatt ctagtattgt aggaactcat
    15601 ataatgatgg aagcagaaga tttaggatta ggtagcgttt gggtaatgtc gtttgatcca
    15661 gaaaaaatta aacaaacata taatctgcca gaagagtttg aacctgtagc aatattttca
    15721 gtaggatgcg cagatgaaaa atcaaaacca ggtaaaatgc attttgataa aaaatcttta
    15781 gaagagacaa ctttttataa ccgattttaa taaatattga tatatgttac taaatataac
    15841 tctaatattt tagattaaaa acgtcacaaa ataactattt ctaaaaacac atttaaagac
    15901 aattaagctc cttactaagt agaatccaag atgataagcc agttgcagaa tgtaaagaat
    15961 agatgtatta ttacacatga tgagtatgta acatctaaat gcactagaaa atttaaatta
    16021 actcaggtaa tttagaactt tgtccataga tctaaactct tactataata tttttataat
    16081 aaattaataa cttaaatata ataaaagata catttttgat gtatcttttt tatttaaata
    16141 tttaattact tttaattatt ataagtgcca taataatgaa tttagaaaat ccatatacag
    16201 attacacaaa gccctccagt cgatagaaga ctatgaaaaa agtattaaat taaaaaacga
    16261 cttactatag taaaattaat ttagctaaag gaagtcgttt ttttgaactt ttttggactt
    16321 tctatttctt tttaaaattt tttatatcct gtggcatttt tgcttgatga tttaaaaatg
    16381 tacaagtaga gttagctgat aatttaatag cacttaccgc taaagatcct actttttcca
    16441 atactgttga agttatatct tttttcataa gttagtcact cctttcttga tgagacctag
    16501 aattaacatt ataaaaatac atacgataac agatgataaa tacatagcat actcataagt
    16561 tatcgtaaaa ttaaagcata tagctgaaat tactaataga atactacaga gatatattac
    16621 tattttttta tatttttttc tttctttgct acttaaagga ttatgtctat gctcttgtgg
    16681 cactaaaaaa agtatgccca tataacttac aaatgctatt actactacaa gtgtagttga
    16741 atttgaatta attagtttat ctaacacgta tatattagtt aggtacattg taatgaaaca
    16801 aaacaaacat cttttataat tttcagcatg aaacccacca gcaaattgcc ttattgaaca
    16861 gtaaaatact aaaaataata gtgtttcaat aaatctattt aacattgttc ctatagttag
    16921 tataataatt atgttaccta tagaagctat taatgtctca aatccaaatg aatagatatc
    16981 ataatcttca tattctattg tcttcttggc aattaaaagt gatgtaatct tattagcaca
    17041 agacttaacc attttcatcc cctccaaata tttttcatta attaaactaa tttaagcttc
    17101 ctattacctt aaatcgattt ctaactaaag gtatcaaaat agtcatttca aaatcatctt
    17161 cagttaaatc tagtactacc tctcccttat acttttctac tgattttatt atactattta
    17221 taccaattcc aaatggcaga gatgcaagag gttcctgctt atctgtaagt attttattct
    17281 ttagaatgag tttattagtt ttgggatttt tgcactttat tacatgaaat ttatttacaa
    17341 ctttacccga aatatctatt ctctttatca tactattgtt tctaatattt ttacacgctt
    17401 ctattgaatt atcaatcata tttgaatata tacaacatac atctgcggtt tccataaaat
    17461 cgcacttaga aaaatctaca tctacattaa aatctataat actttcatca caaataaatt
    17521 ttttctcatt taaaagtaca tctaaaaata aattatgtgt atcataaaaa gtgtttattt
    17581 gttttttctg taaacacaaa tagtgtttat attgtaattc cgtcttttct ttaattatct
    17641 cgttttctat tcttgaatca ttacgtttca ctatgttgga tacaattaaa attaatgatg
    17701 cgtttgaaag taataataca catgatgcag agaatgcaat tatactttgt gaatagctaa
    17761 tagctgatat agaaaataat aaactaataa ttgtaacaat actaatgatg ttggcaataa
    17821 ttggaataga tatgtatata tattctcttt tgcttatttc aattcttaat ttaattcctt
    17881 taattatagg tattaatatt aatagcaatg acttagccat aataatattt tctaacctaa
    17941 gtacgttatc tcctaaaagt acatccatac taggaactct gtttattaaa atcactaaac
    18001 taccagctat tgtatcaact ccagctaaca acataaaata aaataaagtt ataaatacac
    18061 atttcaatat tgttacttta taattagatt tatatattgt gaaagccata gctataccaa
    18121 ttaataattt taaaatcgga ttaacttcaa ttacagtcat gagaaaaagc acacaaatag
    18181 gtgctagaaa taacagattt gagactaata tactcctttt tgcttcactt gcttcatcaa
    18241 aaatatactt taacacatac cactcaatta ctcctgctat tagtgtcatt aacaaccaaa
    18301 acaaattcga atctagcaaa ttatatcacc aaccttgatc tggataatac tatcctcata
    18361 aataactatt ctatacatag tcacgccccc tataagttta atagttgcag tataagaatt
    18421 attttgattc tttgataaaa taatttattc ttatttaaga aaattaatta atacgagact
    18481 atgatataaa ttaagatcaa attacaaacc tataaagccc tattgattga ttgtttaaac
    18541 taaattttgc cataaaacgt gttcatgtat aaaaataatt cgacgtaagt taagtcttat
    18601 cctttttttt tgagtatttt ttttacagtc tccgaaagta ggatattttt tttaatatat
    18661 tactaatcga tgccataata ttaatattgt caaaaattca ttcagatact tacattaatt
    18721 cagttaagta gtcactatat gtttaataaa gattatgaaa atgctaaaga atgtttaaaa
    18781 agaatatata aacctagtca aaattctgac ttgattttgc ctagcatatt tatattacaa
    18841 aaaaaatttg atgaaggtag aaagcaattg caacatagtc taaaaaatag tttagcagaa
    18901 gcaacttcgt ttagttggca attgggaaca tcttacttaa ataaagataa tttagatata
    18961 gatagagcga ttgactattt taatatggct gtaaaaatta gagaatctga agggaatgta
    19021 cttaatacaa tttcgttttc ttgtaaacaa aattgtttta ttatgcttat tttaatcttc
    19081 aatattttat ttacatctta ctttttaatt attccttaaa aacttattta gaaaactcta
    19141 gttaaaaagc ccttaaaatc catttattta gatcatccta agggctttta attgtacatt
    19201 taaccaaaac tattcttaag cgtaaattta gctattagtt gcttttcctt ttatgggtag
    19261 tatccggaaa atatgtattt tcccaaaaga tactccttcg tgcaaataac atataaatta
    19321 tatagaattt aaaccaactg agtaagatgt cacaaattaa cccctttgag taagttacat
    19381 cagaaacatt gaaatttaat tatcattgga gtattatatt aaaaaatgtg ctacaaatgc
    19441 gacaattata attgactata aattatagag gtgatataaa gatgaaaata ttatacttta
    19501 caggaacagg gaacaattta catgttgcaa aagtaatagg cggagaattg tattctatac
    19561 caaaattaat aaaagaaaat aaatatgaat ttgaagatga taaaatagga ataatttttc
    19621 cagtatatac tctggggcta cctaaaatag tagaagaatt tttaaataaa gcaaaattag
    19681 aaagtaaata tatatttgct atagctactt atggaactac tccagggaac tcagataaac
    19741 aacttttaaa gattgcaaag aagaacaatt ttgaattttc ttatataaat agtgtttgta
    19801 tggttgataa ttatctacct atgtttgata ttgaaaaaga aatagcaaaa aaatcaaatg
    19861 aagatataga taaaaatatt aatagtattg ttaaggatat agagtcaaat aagattttta
    19921 taaatagtaa tgccaatata gctcttcgta ttataggaag tctaatatct aatgattata
    19981 gtaaacttac tgataaattt attattgact ctaataagtg tatcgagtgt ggaatatgcg
    20041 aaaatgtgtg tcctgtaaat aatgttaaaa taatagataa gagtgctaag tacaatggtg
    20101 aatgccaagg atgtcttgct tgcgtaaatc actgtcctaa gtatgccatt aagcttaaaa
    20161 aagaaaaagg aactgctaga tttattaatc cgaatattac tttaaaagaa attatagaat
    20221 caaataatta atatagtaag aaaggtctaa tacacttatg tataaagtaa ataataatcc
    20281 tttagcaatt caatctcaac atatgattgc agatgcattt ataaatttat tgcaaggaaa
    20341 tgattacaat gatattacaa taactcaaat atgtaatgaa gcaatgctat ctagaagaac
    20401 tttttatcgg aatttcaaag taaaagagga tattattgaa tttttagtag ataaaatgac
    20461 taaagatata tacaagggca tagattatgg caacgtatca atggaaaaat tgctttatac
    20521 atatttttca tactggaaaa ataatagaga ttttatacaa attatatata caaacaattt
    20581 gtttttttat ttaagtaaaa aatttataga ttatgctaaa ttgtatatta aatgtgatac
    20641 agatatgaaa agtaaatata agtactttgt taatgtagat aaatatgtag ttagatatat
    20701 tgactcaact ctttcttgta tcttagaact atgggtcgaa aatgacttta aagaatcggt
    20761 agaatcaata tctaagctta catatgattt aatcaataaa tcatagtata aatataataa
    20821 ttaaagtgtg aaatatagat caaatacggg ggacaccaaa ctataaaagt acaagatccg
    20881 actcctgttg ctactattga atacatgccc aatgatagag gtagtttctt gtcttataac
    20941 atttggctat acagatgatc cggatgagca ggaaaataaa ctacacaact ttgtttattc
    21001 taatagaaaa ccgttagatc aacaatatac gacggaaggt acacaaccga catggtttat
    21061 ggtgggaatg aaatcagtag aaaaagctcc atctgccaaa aatttaagat taccaatttt
    21121 taataatgat aacggagtgg taacagtaac acttcctgac aagagccttg atacgagtag
    21181 tgcaggagta gaagttgacc taggaatagc aaagctgcat tttgaagttg gtgcaggaaa
    21241 aggaacgtgg gaatggggcg ataatgcaaa attccatatc taaaatagtt aacaatcacg
    21301 gtcacgagct tgttaaatgt caaataaatt ttacctaaaa acaatttaag gattattagt
    21361 aaaataaaat agcccttaaa atcatttatt tggattttaa gggcttcgct atcttttatt
    21421 atttattaat atttaattat tagtgccata atgttaatta ctgtacaata aataatatat
    21481 tatatgtatt ttcgatagtt atataagtct ctaatatttt ttattttaaa aaataataca
    21541 taaaatttac cataacatat aaattaaaat ggggttaaca ttactaatga tgagcatttt
    21601 tggtgaaaaa ctttctgaat ataaatataa gaaagaagaa aaagaacgcc aagaaagact
    21661 attgctgaaa aatagggtgt ttctagaaca acatataagc tatctagaaa aaattctgac
    21721 aagaactagt tagtttagta aaaagcgttc agacttaaaa tcatttagag ttgagaaatc
    21781 tttgacagag tagttctagc atactctaat agttatttgc ttcaccataa tagtttaaag
    21841 caatataagg tacataatat ttgaaatatt tttttggatc atctataaga ttcactaaat
    21901 atcccggttg aaaatatact aagagataac gcaagtgtca atattctttt tgatattttt
    21961 tcttttgaca taataattat acctctcctc aatttttaat ttctttgatt aattatttga
    22021 aatatccctt tcatctatta aactattata gacataaata tttgacactt ttttattttt
    22081 ttattaattg ccgcaattta cctcattaaa agatataaag atagactccc ttttgaaaag
    22141 atccgttcta ctttccagtt tctttgcata cgtcaatcca ctcaagtgca tttccatatt
    22201 ggaaaatttc atctggtgaa agttctacaa cgtaatttgg gcttccgcag gcaggaaata
    22261 gtgtatcata tttattaacc gaatcatcaa tataaacggg aatatcctca ggaattgcga
    22321 atggggatac tccgccaaca gtttgacccg tcatatcagt aacttcttgg gccgtaagca
    22381 tgcgagcttt cattccaaaa tattgtctaa acttcttatt atcaatcact gcatcaccag
    22441 ccataaccat catcatacaa ccttcatctt tcctcaaggt caaggtcttt gcaaccctag
    22501 cagcctctac gccaatcgtc tttgccgctt cctctactgt tgcacaggaa ccatcaaatc
    22561 ctttaattcg atctttcaga tttctttctt caaaatattt ttttacaagt ttaaaagaca
    22621 taataatcct ccatttttta ctctattttt ttatttaata cactttttct atctgagggg
    22681 tacaacttac acaatcatat tctattccta tcactgttag gttaaacaat agatcatcaa
    22741 gtttgaaaaa gttgcctttg caatttcact gccagctgtc cgctttgagt ttcatatata
    22801 atcctattct ccgtccattg taaactatcg caaattataa atatcgtttt cttttactct
    22861 aaaagcaatt ttggcaatat cgtttttaat agcgattttt tgtatcattt catcgaaata
    22921 ctactttaca aaagcaaata ttttctgaat tttcctcaaa taatttgtct acagacgtat
    22981 caataatgta ttattaattt tataacttcc tataatttct actctaatac taaatgaata
    23041 gcactatata aaagcaaaat agacatacat atatttgaaa ttttccaata ctttctaagg
    23101 aaacttccaa gcattgaccc tgcaactgcc caaatatgtg tagctccgtt gccaatcaag
    23161 gataatatca taacaaaggc gcaaataaca agcggacttt gataatatgg cataataaat
    23221 ccagtaaatg ccgtgattcc ccataaaata attttcacat ttgcaaattg aagtataaaa
    23281 cccttactga aagattgaca gtctgcctgt gaattcgttt ctataggttt actaaatgca
    23341 acatgataag caagccaaaa aatataaact gctcctatat atttcatata attcatgata
    23401 tttggcagaa aaattagcag tgcactactg aatattccac aaattaccat gatacaagta
    23461 aaacctgtgt atatacccaa taggatgttt ttgctttttt ttattcctgc acttccagta
    23521 gcgtttaacg ccaaaatatt attaggccct ggcgaaaggg ctgtgataac tgtataagat
    23581 aaaaaagata cccaaacact gtaattcact tgaaattcac ctccatattg attataataa
    23641 cagtaattaa ttaatcaaac aaatcgaatt attaaaatta ttaattcaat ataatcgaac
    23701 tatgggaggt agaatcatat cgatctgaaa tatctaaata catttaaaac tattttacaa
    23761 actggtagct ttataaatgc tgcccgtaaa ctgaattata cacagtcaac aatcaccttt
    23821 caaatacagc aattagagaa tgaattatct gtaaagctat ttgaaaaaat tggtcgaaaa
    23881 atggttgtca ctcaatctgg gaaagatata ttaccttata ttgatacaat tttacaatcc
    23941 gttgagcaac ttgaaaatta cggaaaaaat atatctgaac taacaggtag cttgaaagtt
    24001 gctattccag aaaccttatt gacatataaa atgcagccag ttctaaaggc atttagggag
    24061 caggcccctg gtgtgaaact ttctgtacag acactcaatt gctacgatat aagagataaa
    24121 gtcatcgatg gtagtataga catcggcatc cactatgatg ttggtggata tgtaccatct
    24181 atggtgattg aaaaatttgc tgacttttct cttgtgctga ttgcttctcc tatattagat
    24241 cctcagtttt gcgactttaa aaccacaggg cagagaaata aaatatgctt gattaccaat
    24301 gatccaaata gtatttttca aggtatatta aataactatt tagaagagaa aaaaattgaa
    24361 cttgagagta tcatggaact tgggagtatc gaagcgatca agggatgtgt tgctagtaat
    24421 ttaggggtgt cttttatacc aagctatgtg gctgaaacag agctggaaaa cggaacctta
    24481 catgaggttg aaatagatct tttgaacaaa aaaatatcag ctgtttgtac ttaccataaa
    24541 aacaagtgga ttagcccagc gatggaatta tttatcaggc taacaaatga acatttaagt
    24601 gatgtctagt aaaagtttga gtcctataga tcttatgtaa ttaacacatg tgaaaatgtg
    24661 caactatgac aagtctgaca attataatac ctagactatg ttgctctaaa tattcacaga
    24721 aatagacaat gatattaaat ctaagtacca ataaacttaa tcatattata aaaataacta
    24781 aaataaaaaa gaaagtggat aattattaat aaaatggatc ctatatagtg gacacgagaa
    24841 aaagcgtgtc tatctatata ggatccattg taaaaaataa agtccttttt attttaagca
    24901 acatatgcaa tttttatatt tagtgactta aaaagaattg agatataatc aatctatgcc
    24961 aactgttatg agtacataat taaataatgc cgacttgtac ctctggacat ccataaacta
    25021 cattctaaaa gtgatgattg ccaaaccttt attatgcgta aatgatagct ataaatttat
    25081 taataaattt ttagccttcg tctattataa atagaataac tgatttttat ataaattgtt
    25141 atataattaa agataaccat attttttaat ctagaaatat tttaaatata gagttaactt
    25201 tgaaaagagt aaagtgattg aaaaattcaa aggaggaaat gcttgtatat actgctattt
    25261 gcattaaaat aactcgttaa agtatattaa gttaaataat actttaatgg gttaaacacg
    25321 gaacaattta gaataaattt ttatttaaat taacaatatt agcttctttt atatattctt
    25381 ctattatact tctccctaca ttgaaataac ttatacattt atcaattata gctgcatcac
    25441 tactaactac tctatctagc ttttctaaaa ttacatctgc attatttact agcttaactt
    25501 cagttttaat tttccaattt tgcgaacaat ctaatatttt atatttcaaa ttacccgaat
    25561 tagaaactgg ggaatctagg taaaatttca cttctttcgc atcatattta ttcaaaaatt
    25621 ctcctattaa atttaatgct tcatctgttt tatcaataat tttatatgtc cctctaagtc
    25681 ctgctaaatc tctaatattt ccatcactac ctataattaa aatacctcca gataacgcaa
    25741 cttctaatgt tattatcaaa ttaaatccat ctatatatat aggaccttca cttatttcat
    25801 ctatagaaat tttttttgat tgccttatta gtttcttttc ctctgaacat atagctcttt
    25861 ttagcgcatc tctttgtctt agtgaaaatt ggtatctatc tcctgtaaag tttactactg
    25921 gttctatttt atattctctg tttattaacc attcaatttc ttcttgagcc tttgttaatc
    25981 ttgttagttc tttatatgaa aaccatcttt tatcattttc attaaatcct cttttggata
    26041 ctttagtcat actttgattc accaccttac tgcagttgta caacgcacat aaaaataaga
    26101 cttcttaata taaaagtttt atttcttagt ataactctta aaataataag ttatacttcc
    26161 gctgattttt aaccaaagct tcttctcctc cttaagacct ccctctatta ataaaattaa
    26221 gccaggactt aagcccccaa tactaagtcc ataatgttag aaaccgtatt acttatttgt
    26281 gatatggttt ttaacattgc agattatcct ttgataaatc tataagagat ttcattataa
    26341 acaaataaaa aggattatat atcattatct catgatatac aatcctaata taattttacc
    26401 acttaccgtt agccatctct attcttaaaa ctgttaagtt taattagcag ccatcttaat
    26461 tcagtcaaaa ttttgtttga ttaaataatt gcaaaagaga taaataatga cttttaagcc
    26521 tcacagtata atgctatccc tataataagt cttccatcag atactgtaac agataagttt
    26581 tcataataca ataacggatc catctgtttt ttgaatagca ttccagttca aagctgtacc
    26641 caacaatgcc tgccagtttt tccaaatctc tgattctaaa atctctatat ccaagataca
    26701 tcatttttta acctaatttc acctattacg cagaaacagt tctttcatat agatagaact
    26761 taatcacatt ttttatcgga acctgatagg tggtctcccc gcatcgtact gatggtttaa
    26821 ctgtagcatc atattctgta actgaaaaaa cattacaact tatcgatgtt ttcttaagcg
    26881 ttataaaaag tccaccttcc attaaataac tgaataaggt ggacttttaa attttttagt
    26941 attcaaacaa atctcaatca acatcaattt ctgttatcat tgtgttctta cattcacatg
    27001 atgttataaa taaggctata ttggctattt cctcagttca cttgtgctat tt
//
