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Overview
1.1
1.2

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP076620.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | cyclic-lactone-autoinducer | 1,243,175 | 1,263,961 | yersiniabactin | NRP + Polyketide | 2%
Region 1.2 | ranthipeptide | 1,526,256 | 1,547,629 |

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | cyclic-lactone-autoinducer | 1,243,175 | 1,263,961 | yersiniabactin | NRP + Polyketide | 2%
Region 1.2 | ranthipeptide | 1,526,256 | 1,547,629 |

No secondary metabolite regions were found in these records:
  NZ_CP076621.1
  NZ_CP076622.1

Compact view
NZ_CP076620.1 - Region 1 - cyclic-lactone-autoinducer
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,243,175 - 1,263,961 nt. (total: 20,787 nt) Show pHMM detection rules used
cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | cyclic-lactone-autoinducer | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000916.1 |  | 0.19 | Other | molybdenum cofactor | Staphylococcus carnosus
BGC0000607.1 |  | 0.12 | RiPP | micrococcin P1 | Macrococcus caseolyticus
BGC0001686.1 |  | 0.08 | NRP | N-octanoyl-Met-Phe-H | Clostridium sp. CAG:567
BGC0000897.1 |  | 0.07 | Other | dehydrophos | Streptomyces luridus
BGC0001365.1 |  | 0.06 | NRP | clapurines | Claviceps purpurea 20.1
BGC0001055.1 |  | 0.06 | NRP, Polyketide | yersiniabactin | Escherichia coli
BGC0000343.1 |  | 0.05 | NRP | enterobactin | Pseudomonas sp. J465
BGC0001053.1 |  | 0.05 | NRP, Polyketide | tubulysin A | Archangium disciforme
BGC0001580.1 |  | 0.04 | Polyketide | ebelactone | Kitasatospora aburaviensis
BGC0000495.1 |  | 0.04 | RiPP | actagardine | Actinoplanes garbadinensis

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000916.1 |  | 0.51 | Other | molybdenum cofactor | Staphylococcus carnosus
BGC0000607.1 |  | 0.40 | RiPP | micrococcin P1 | Macrococcus caseolyticus
BGC0001686.1 |  | 0.31 | NRP | N-octanoyl-Met-Phe-H | Clostridium sp. CAG:567
BGC0000897.1 |  | 0.28 | Other | dehydrophos | Streptomyces luridus
BGC0001365.1 |  | 0.25 | NRP | clapurines | Claviceps purpurea 20.1
BGC0001055.1 |  | 0.24 | NRP, Polyketide | yersiniabactin | Escherichia coli
BGC0000343.1 |  | 0.23 | NRP | enterobactin | Pseudomonas sp. J465
BGC0001053.1 |  | 0.21 | NRP, Polyketide | tubulysin A | Archangium disciforme
BGC0001580.1 |  | 0.20 | Polyketide | ebelactone | Kitasatospora aburaviensis
BGC0000495.1 |  | 0.19 | RiPP | actagardine | Actinoplanes garbadinensis

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP076620.1 - Region 2 - ranthipeptide
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,526,256 - 1,547,629 nt. (total: 21,374 nt) Show pHMM detection rules used
ranthipeptide: (TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085 or SPASM)) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716 or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or YcaO or TIGR03882)))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | ranthipeptide | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001387.1 |  | 0.17 | Other | nucleocidin | Streptomyces calvus
BGC0000599.1 |  | 0.17 | RiPP | thuricin CD α, thuricin CD β | Bacillus thuringiensis
BGC0002009.1 |  | 0.17 | Polyketide | kanglemycin A, kanglemycin V1, kanglemycin V2 | Amycolatopsis vancoresmycina
BGC0000486.1 |  | 0.16 | RiPP | butyrivibriocin AR10 | Butyrivibrio fibrisolvens
BGC0000500.1 |  | 0.16 | RiPP | carnolysin A1, carnolysin A2 | Carnobacterium maltaromaticum
BGC0000616.1 |  | 0.15 | RiPP | amylocyclicin | Bacillus velezensis FZB42
BGC0001862.1 |  | 0.15 | RiPP | geocillicin | Aeribacillus pallidus
BGC0001930.1 |  | 0.15 | RiPP | pallidocin | Aeribacillus pallidus
BGC0001551.1 |  | 0.15 | RiPP | citrulassin E | Streptomyces glaucescens
BGC0000554.1 |  | 0.15 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001387.1 |  | 0.48 | Other | nucleocidin | Streptomyces calvus
BGC0000599.1 |  | 0.48 | RiPP | thuricin CD α, thuricin CD β | Bacillus thuringiensis
BGC0002009.1 |  | 0.48 | Polyketide | kanglemycin A, kanglemycin V1, kanglemycin V2 | Amycolatopsis vancoresmycina
BGC0000486.1 |  | 0.46 | RiPP | butyrivibriocin AR10 | Butyrivibrio fibrisolvens
BGC0000500.1 |  | 0.46 | RiPP | carnolysin A1, carnolysin A2 | Carnobacterium maltaromaticum
BGC0000616.1 |  | 0.46 | RiPP | amylocyclicin | Bacillus velezensis FZB42
BGC0001862.1 |  | 0.45 | RiPP | geocillicin | Aeribacillus pallidus
BGC0001930.1 |  | 0.45 | RiPP | pallidocin | Aeribacillus pallidus
BGC0001551.1 |  | 0.45 | RiPP | citrulassin E | Streptomyces glaucescens
BGC0000554.1 |  | 0.45 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names