LOCUS       NC_004320.1            10546 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_004320.1 Corynebacterium efficiens YS-314 plasmid pCE3, complete
            sequence.
ACCESSION   NC_004320
VERSION     NC_004320.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:00:17
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 33602
            Orig. end    :: 44148
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10546
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[38602:39148](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5546
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..10546
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10546
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             1807..2517
                     /locus_tag="ctg3_38"
                     /transl_table=11
                     /translation="MGIFSGRHFPREIILWAVRWYCRYGLSYRDLEEMMTERGVPVDHS
                     TIYRWVQKYAPELDKQTRWYRQVPDWQARSWRVDETYIRVGGKWCYLYRAITAGGHTLD
                     FYLSPKRNVAAAKRFLAKTLRSNTITGSPRVINTDKAPSLARAIAELKSEGIYPQTVEH
                     RQVKYLNNVIEGDHGRLKRILGPKGAFKNRTSAYRTLKGMEAMHSLRKGQGAMFAYGQP
                     NPDAVIVSRVFEAA"
     PFAM_domain     2026..2445
                     /aSDomain="DDE_Tnp_IS240"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13610.8"
                     /description="DDE domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_38_0001"
                     /evalue="1.40E-46"
                     /label="ctg3_38"
                     /locus_tag="ctg3_38"
                     /protein_end="213"
                     /protein_start="73"
                     /score="158.2"
                     /tool="antismash"
                     /translation="RSWRVDETYIRVGGKWCYLYRAITAGGHTLDFYLSPKRNVAAAKR
                     FLAKTLRSNTITGSPRVINTDKAPSLARAIAELKSEGIYPQTVEHRQVKYLNNVIEGDH
                     GRLKRILGPKGAFKNRTSAYRTLKGMEAMHSLRKGQ"
     CDS             complement(2685..3812)
                     /locus_tag="ctg3_39"
                     /transl_table=11
                     /translation="MVRIGTLLDECGRPIDKVQIIHRGKNNTRIKRSTDYGRSWEATDQ
                     QVPTDTVLFDDGQRFAQHSRNPQHATYMGSFGEPGARLRIHRVYKHITKAKVYLGEKTW
                     TPIQDILTSSILFDGGASAGWMIPSWVEKDTTDQGNNAPEVEEETATSVKPQPGGSTDK
                     HLAMQSAAVAESSTPLLPPVASPRGQRFSYIRVSSTDQNLARQRDMIGAVDKEFVDEVS
                     AKSRAGRPGLERCIDYLRDHDELYVASIDRLARSLVDLRSIIDQITAKGASVHFIKENL
                     VFSKDSTDPRATLMLGILGSFAEFERAIIRERQAEGIALAKKAGKYKGRKRVLTPAQVE
                     QAQARVEAGESKTTLAKDLGVSRATLYRALSAPEL"
     PFAM_domain     complement(2700..2828)
                     /aSDomain="HTH_7"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02796.17"
                     /description="Helix-turn-helix domain of resolvase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_39_0003"
                     /evalue="5.20E-09"
                     /label="ctg3_39"
                     /locus_tag="ctg3_39"
                     /protein_end="371"
                     /protein_start="328"
                     /score="36.1"
                     /tool="antismash"
                     /translation="GRKRVLTPAQVEQAQARVEAGESKTTLAKDLGVSRATLYRALS"
     PFAM_domain     complement(2832..3242)
                     /aSDomain="Resolvase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00239.23"
                     /description="Resolvase, N terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_39_0002"
                     /evalue="1.30E-35"
                     /label="ctg3_39"
                     /locus_tag="ctg3_39"
                     /protein_end="327"
                     /protein_start="190"
                     /score="122.7"
                     /tool="antismash"
                     /translation="FSYIRVSSTDQNLARQRDMIGAVDKEFVDEVSAKSRAGRPGLERC
                     IDYLRDHDELYVASIDRLARSLVDLRSIIDQITAKGASVHFIKENLVFSKDSTDPRATL
                     MLGILGSFAEFERAIIRERQAEGIALAKKAGKY"
     CDS             3978..4199
                     /locus_tag="ctg3_40"
                     /transl_table=11
                     /translation="VKTPSFIFWWSLKADVLRHSRIPGKRSPHPGSVAREVKHRALAFP
                     QIECIASIPFNVLFLNAPFGPRICFSRP"
     CDS             complement(4206..4685)
                     /locus_tag="ctg3_41"
                     /transl_table=11
                     /translation="VGGAVVLPLRRELPRPGRNDDRTRRASRSHHYSHRWVQKYAPELD
                     KQTRRSRQVPDWQARSWRVDKTYIRVGGKWCYLYRAVTAGGHTLDFYLSPKRNVAAAKC
                     FLAKTLRSNASAGSPRVINTDKAPSLAKAISSVEGGRHLSIDGRASSGEIPQQCH"
     PFAM_domain     complement(4272..4508)
                     /aSDomain="DDE_Tnp_IS240"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13610.8"
                     /description="DDE domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_41_0004"
                     /evalue="5.00E-25"
                     /label="ctg3_41"
                     /locus_tag="ctg3_41"
                     /protein_end="138"
                     /protein_start="59"
                     /score="88.4"
                     /tool="antismash"
                     /translation="RSWRVDKTYIRVGGKWCYLYRAVTAGGHTLDFYLSPKRNVAAAKC
                     FLAKTLRSNASAGSPRVINTDKAPSLAKAISSVE"
     CDS             5001..5546
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Lactococcin_972"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_42"
                     /sec_met_domain="Lactococcin_972 (E-value: 1.4e-09,
                     bitscore: 30.4, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVKRRLLLAVAAVALFTSSPGVATATPGEKASQGPPLASQEIAE
                     LAEANAAAGVYGESSELEVSEVVLTRDENGTPTSGMVSYPLEYKGNSALIQPLTNAPGV
                     GGGTWNYGSRIDIRLGKVCYSEYHHPTLMHSASVEMDGMTNSVTEGPNRTAKASVRLPF
                     SELEEGKYCNAFWSTSDW"
     PFAM_domain     5313..5480
                     /aSDomain="Lactococcin_972"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09683.12"
                     /description="Bacteriocin (Lactococcin_972)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_42_0005"
                     /evalue="1.10E-13"
                     /label="ctg3_42"
                     /locus_tag="ctg3_42"
                     /protein_end="160"
                     /protein_start="104"
                     /score="51.5"
                     /tool="antismash"
                     /translation="GGGTWNYGSRIDIRLGKVCYSEYHHPTLMHSASVEMDGMTNSVTE
                     GPNRTAKASVR"
     CDS             5725..6072
                     /locus_tag="ctg3_43"
                     /transl_table=11
                     /translation="MTAGTTALLHSFFERSFARDGVGVPYEVCIAAIGIAFSLFILYCG
                     FLLVAHWNKQKFARAVQAFIAVCVFVSLSSTAWFFSETGQFNIVSVICLSFVFLGGALG
                     VAVAERIRLEV"
     CDS             6119..6277
                     /locus_tag="ctg3_44"
                     /transl_table=11
                     /translation="MEHHSDDCSNDVCEALDRVPVLSTTALNVCPMNRQVHRAYPYFLA
                     PPACRMG"
     CDS             complement(6832..7047)
                     /locus_tag="ctg3_45"
                     /transl_table=11
                     /translation="VDLADDGGLGKALFFYPRQISSSILRSDKDKYFSACLGPGRQALQ
                     TSFSNPTKQGKHIPHQCLNRAYLQIH"
     CDS             complement(7134..8000)
                     /locus_tag="ctg3_46"
                     /transl_table=11
                     /translation="MWGVVENHFRHAPLCHMITTNATSQTITCNSPVHPCRVRAMSNGK
                     WLEAEPKETWLVANDNEHGKKWFGRTVQITRQDRGLSVAELASRVDLAEGTIRAIERGG
                     RAPSEASGLRILAKLFTSDQWSKNHFGPNLHAVKDPETKAPVIVEFGAKVRGDNGSWSR
                     DRTPEDDMSDRDNEILRKVEKNLLENPEKLQRLKGVFSGFNESVKTYVAHLNEPINDEN
                     LGKVTRRLPAITNLQADHLDKLLWLWGLINTGRASREVIDEVQRVDKILGSFFSEDELK
                     EFSEDED"
     PFAM_domain     complement(7635..7775)
                     /aSDomain="HTH_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01381.24"
                     /description="Helix-turn-helix"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_46_0006"
                     /evalue="1.00E-05"
                     /label="ctg3_46"
                     /locus_tag="ctg3_46"
                     /protein_end="122"
                     /protein_start="75"
                     /score="25.6"
                     /tool="antismash"
                     /translation="RQDRGLSVAELASRVDLAEGTIRAIERGGRAPSEASGLRILAKLF
                     TS"
     CDS             8023..8166
                     /locus_tag="ctg3_47"
                     /transl_table=11
                     /translation="MELLNNFADETKRRKMLKDLNLVIESFGNIASVILPLIKGNGPIQ
                     GR"
     CDS             8144..8422
                     /locus_tag="ctg3_48"
                     /transl_table=11
                     /translation="MVPSREGNRAPRACAQQHGNHAKMQEWGLCKCLQTSPFQHPFEPR
                     PAFLVAPALTRAFLRGATPHCRVRGSEVGGPSEKTVTLMNFDNVYMT"
     CDS             complement(8580..8918)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111:GCN5-related N-acetyltransferase (Score: 67.6;
                     E-value: 2.1e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_49"
                     /transl_table=11
                     /translation="VFALQCDEFGERYCGNIEARLVDASIPSVSIGYNTAPWARGRGLQ
                     ARALELLMKHCFANGINRVEVRAAVDNSASRHVAEVAGCRFEGIMRHGENLHGKLQDLA
                     VYAKLAAD"
     PFAM_domain     complement(8667..8879)
                     /aSDomain="Acetyltransf_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13302.9"
                     /description="Acetyltransferase (GNAT) domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_49_0007"
                     /evalue="1.40E-07"
                     /label="ctg3_49"
                     /locus_tag="ctg3_49"
                     /protein_end="84"
                     /protein_start="13"
                     /score="32.3"
                     /tool="antismash"
                     /translation="CGNIEARLVDASIPSVSIGYNTAPWARGRGLQARALELLMKHCFA
                     NGINRVEVRAAVDNSASRHVAEVAGC"
     CDS             8922..9068
                     /locus_tag="ctg3_50"
                     /transl_table=11
                     /translation="MTGLSGCEIESHLTSVFVRYLRIFLHAIINGAQINIIGITCFQPT
                     QSK"
     CDS             complement(9200..9424)
                     /locus_tag="ctg3_51"
                     /transl_table=11
                     /translation="MTATIPSKATKDLILEGKREHVIASDWSQAYMQARMIVWLAEHGK
                     VGVGAVDVAVEELWMSRWQMHRVLLTVCL"
     CDS             complement(9738..10217)
                     /locus_tag="ctg3_52"
                     /transl_table=11
                     /translation="MVADYLSQHHAGIRVSTIRGSGPTVVFLIVDVITHGPIISSVLQS
                     SIQRLIAGSAILIALVIFGRFTSHRTFTHSLLGLVSLSAGVWLLCPPLTAAFAAGFISH
                     VLLDLLNKQPIQIFYPIEKGKFCLKLCYANGVMNTVFFLLGIVGVLCWVGKVALT"
     PFAM_domain     complement(9798..10052)
                     /aSDomain="YdjM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04307.16"
                     /description="LexA-binding, inner membrane-associated
                     putative hydrolase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_52_0008"
                     /evalue="1.90E-16"
                     /label="ctg3_52"
                     /locus_tag="ctg3_52"
                     /protein_end="140"
                     /protein_start="55"
                     /score="60.0"
                     /tool="antismash"
                     /translation="ILIALVIFGRFTSHRTFTHSLLGLVSLSAGVWLLCPPLTAAFAAG
                     FISHVLLDLLNKQPIQIFYPIEKGKFCLKLCYANGVMNTV"
ORIGIN
        1 ggtgggcgga gggagcggtg ctgctgttct tgttcagcct cggccacgcc ctcgaggagt
       61 acgccctcag ccgcgccagc aagtccattg aggccctcgc cgaactcgcc ccccgccacg
      121 ccctggtgcg ccgcggtgat accgaacccg tggaagtgcc cgtggaggaa ctcgtggtcg
      181 gagacatcgt ggtcatccgc ccgaattccc acatcccctc ggacgggttc gtgatctccg
      241 ggatgtccgc cgttgatcaa tcagcggtca cgggcgagtc gatccccgtg gagaaggaac
      301 cggtggccga cccacagcgg acgatgcaca cgattgacac cctccccgcc gccaatcgag
      361 tgttcgccgg caccgtgaac gggtccggcg tgctcgagat cgaggtcacc gcgaccgccg
      421 ccgactcaac gctgagcaaa gtcgtcgagc tcgttcgcac cgccgaccag gccgcgtccc
      481 cgacccagca gttcatcgac cggttccagc gctggtacgt gcccgccgtg atcctcgggg
      541 tcatcgccac cttgttggtg tcgatgttcg tgttcgcgca accgttctcc gacgctttct
      601 acctcgccat gaccgtgctc gtcgccgcga gtccatgtgc tctcgcgatc gccaccccag
      661 ccgcggtcct ggcgggtgtg gctcgcgctg cccgggccgg cgtgctcgtc aagggcggtg
      721 ccccgctcga gacactgggc cgagtaaagg cgatagcgtt cgacaagacc ggcaccctca
      781 cgtggggcgc gccccgagtg acctcactgg cccccgccaa cgatacgtcc gaagcggaac
      841 tgatccccac acttgtggct gtcgaatcgc tcagcgatca ccccctcgct gccgcgatcg
      901 tccgcgacct tgccccccgc gtaccggaga ccgagcggtt ggtggccacc gatctctctg
      961 ccctcactgg acgcggcatc actgcgacga tcgacggaga acgggtggaa gtgggcaacc
     1021 tccgcatgtt cgacgagcag cagcttaagc tgcctccttc gctggccgag gcctacacga
     1081 aggcccgcga ctcggggcag acgttgatgg tggtccgtcg tggtgaccgc ttccttgggg
     1141 tcgtcggagt gatggatgcc tcccgcaacg aatctgccca ggtgctcagc atgctccggg
     1201 acacaggggt gggccatctg gtcatgatct ccggcgacaa ccagcgggtg gccgacgcgg
     1261 tcggccggga agtcggcgtc gacacggcga tcggagagct gctccccgag gataaggtca
     1321 cccacatcac gggcctggcc aagacatacc atccgatcgc gatggtcggc gacggtgtca
     1381 acgatgcccc cgccatggcc cgcgccgacg tcggcattgc gatgggtgcc gctgggtcga
     1441 cggtcgcgct ggagacctgt gacatcgcgt tgatgagtga cgacctcgga cgcgtcccgt
     1501 tcgctgtccg gctgagccgg gcgactggcc agatcatccg gcaaaacctc atcgccagtc
     1561 tcgcagtcgt cgttgtcctc atcatcgcga ccttcctcgg gttgaatatc ggcgccgtcg
     1621 tgcttatcca cgagggatcc actctcatcg tcgtcgcaaa cgcgctgcgc ctgctcaact
     1681 tccagaaggg caaggaacac gctggcatcg accacgaaga taagcccacg cactgacgct
     1741 tccccctgcc agggtgctgt tgcaaagttc gggcgacagg aagacctgcg tgaaataatc
     1801 acagccatgg gcatcttctc cggtcgtcat ttcccccgtg aaatcatcct gtgggcggtc
     1861 cggtggtact gccgctacgg gctcagctac cgcgatctgg aagaaatgat gaccgaacgc
     1921 ggcgtaccgg tcgatcacag caccatctac cgctgggtcc agaaatatgc tcctgagctg
     1981 gacaagcaga cccggtggta ccgacaagtc ccggattggc aggcccggtc ctggcgggtg
     2041 gacgagacct atatccgggt cgggggaaag tggtgctacc tctatcgggc catcaccgcg
     2101 ggcgggcata ccctggattt ttacctgtcc ccaaagcgta acgtcgccgc agcgaagcgt
     2161 ttcctggcca agaccctgag gtcgaacacg ataaccgggt ccccgcgggt gatcaacacc
     2221 gataaagcac cctccctggc cagggcaatc gccgagttga agtcagaggg aatctacccg
     2281 cagaccgtgg aacaccggca ggtgaaatac ctcaataacg tcattgaagg agatcatggg
     2341 cggctgaaac ggatcctcgg accgaagggg gcgttcaaaa accggacctc ggcgtaccgg
     2401 acgttgaaag ggatggaagc gatgcactca ttacggaaag ggcagggcgc gatgtttgcc
     2461 tacgggcaac cgaacccgga tgcggtgatc gtcagccggg tgttcgaggc tgcctgagaa
     2521 cgccgacccg cagcgagcat cagaggatga agactgggtc gtcacggctc tccgcctgaa
     2581 gtttgcaaca gcaccctcag actcgaagta atgggtgagt taccgacctg gtaattggag
     2641 aggttgaagg cagatggaga ttattggggt agcagggata attcctataa ctcaggagca
     2701 gatagcgccc tatataaggt ggctctacta acgccaaggt ctttagcaag agtggttttg
     2761 gattcccctg cctccactcg agcttgggct tgttctactt gagcgggggt taagacgcgt
     2821 ttacgcccct tgtacttacc ggcctttttc gccagcgcga tcccttctgc ctggcgctcg
     2881 cggataatgg cgcgttcgaa ctccgcgaat gagcccagga tcccgagcat gagggtggct
     2941 cgggggtcgg tggagtcttt cgagaacacg aggttctcct tgatgaaatg cacgctcgct
     3001 cctttcgcgg tgatctgatc gataatcgag cgtaaatcca ccagggatct ggctaaccgg
     3061 tcgatggagg caacatagag ttcgtcatga tcacgcaggt aatcaatgca gcgttctaat
     3121 cctggccgac cagctctaga tttagcggag acttcatcga cgaattcttt gtcgactgcc
     3181 ccgatcatgt cgcgttgacg ggcaagattt tgatccgtgc tggaaaccct aatataggaa
     3241 aaccgctgcc cacgagggga cgccactggt gggagcagag gtgtggaact ctccgccacc
     3301 gctgctgatt gcatcgcaag gtgcttatcg gttgaccctc caggctgtgg cttaacgctc
     3361 gtggccgttt cttcttccac ctcaggggcg ttatttccct ggtcggtggt gtctttttcc
     3421 acccaggaag ggatcatcca gccagcactg gctccgccgt cgaacaggat ggaggaggtg
     3481 aggatatctt gtatgggggt ccaggttttc tcgccgaggt agaccttggc tttggtgatg
     3541 tgtttataga cgcggtggat acgcagccgg gcacctggtt cgccaaagct acccatgtag
     3601 gtggcgtgct gaggattccg ggagtgttgg gcgaaacgct ggccgtcatc aaataagaca
     3661 gtgtcggtgg ggacctgctg atcggtggcc tcccaggagc gaccgtaatc ggtcgagcgt
     3721 ttaatccggg tgttgttttt accccggtgg atgatctgga ctttatctat ggggcgaccg
     3781 cattcgtcga gcagtgttcc gatcctcacc atgacccacc ttatgtctca atagaattaa
     3841 agatcctatt gcgaagtgta tcataatgcg ggttttggac ttaatgagac agggaatatc
     3901 gctacccgca ctatgtctca ttagggtata ccctaatgag acataatggg tgctgttgca
     3961 aagtcgggcg gagagccgtg aagactccgt ctttcatctt ctggtggtcc ttgaaagccg
     4021 acgtcctcag gcattctcga atacccggca aacgatcacc gcatccgggt tcggttgccc
     4081 gtgaggtcaa acatcgtgcc ctggcctttc cgcaaatcga gtgcatcgcc tccatcccct
     4141 tcaacgtcct gttcttgaac gcccccttcg gccccaggat ctgtttcagc cggccatgat
     4201 ctccttcaat gacattgttg aggtatttca cccgacgatg ctcgaccgtc gatggacaga
     4261 tgccttccgc cttcaactga agagattgcc ttggcgagtg agggagcctt atctgtatta
     4321 atcacccgcg gggacccggc cgacgcgttg gatcttaggg tcttggccag gaaacacttc
     4381 gctgcggcga cgttgcgctt cggggagaga tagaagtcta gggtgtgccc accggcggtg
     4441 accgcccgat agaggtagca ccacttcccg ccgacccgga tataggtctt atccacccgc
     4501 caggacctgg cctgccagtc gggtacctgc cgtgaccttc gggtttgctt atccagctcg
     4561 ggagcgtatt tctggaccca gcggtgagaa tagtggtgtg atcgactggc acgccgcgtt
     4621 cggtcatcat ttcttccagg tcgcggtagc tcacgccgta gcggcagtac caccgcaccg
     4681 cccacagaat gacctcgcga gggaaatgac gacccgagaa gatgcccatg gccctgttta
     4741 ttccacgcag ctcttcctac tgccccaact ttgcaacagt accctttagt gaacgtggtg
     4801 gtcgccgtcc ccgggctggt tggggaagct tgaacggcct atcgccggga gactcggcca
     4861 gtccgaggat tacggtttta tccgagcgat ccttaatcat ccatgagtta tatatcacat
     4921 tccgattcta attatataat tttttcctat gcgacactgg tctcgttcct agttctttat
     4981 cgaaagcagg ttagatcacc atgaaagtta aacggcgcct tttactggca gttgctgctg
     5041 tcgcgttatt cacttcttct cctggagttg ctacagcaac tccaggagaa aaagcttcgc
     5101 agggtccacc cttagcgtct caggaaatag ctgagttggc ggaagcaaat gccgcagctg
     5161 gcgtgtatgg cgaatcgtca gaacttgaag tgagtgaagt tgtgctgact cgagacgaaa
     5221 atggaacccc cacctctggc atggtctcat acccactaga atacaaaggg aactctgccc
     5281 tgatccaacc cttgacaaac gcaccagggg ttggaggggg aacgtggaat tatggatcta
     5341 ggattgatat aaggctcgga aaagtctgct actccgaata tcatcatcca actcttatgc
     5401 actcagcctc ggtcgagatg gacggaatga caaacagcgt caccgagggg ccgaacagga
     5461 ccgcaaaagc cagcgtcaga cttccattta gtgagctaga agaaggtaag tattgcaacg
     5521 cgttttggtc aacgtccgat tggtgacagc cgttttggta agaatagatg ctttttgatg
     5581 agagtgtaaa agatgatgcg cagtgaacaa gagtataaag tagacatcag cggagccgga
     5641 acccaaaagg tagcgaagaa gaaagtccta cgacaggcag tttggacgtt catcacaatt
     5701 gctacttcgc taacttcgct gggaatgact gctggaacga ccgcgcttct tcactccttc
     5761 ttcgagcgtt cctttgctag ggatggtgtg ggagtgcctt acgaggtttg catcgcagct
     5821 atcgggatag cattttcctt attcattctt tactgtggat ttcttcttgt agcccattgg
     5881 aataagcaga agtttgcgcg tgctgttcag gcatttatcg cggtatgcgt tttcgtgtct
     5941 ctaagttcaa cagcatggtt cttttctgaa accggacaat ttaacatcgt cagcgttatt
     6001 tgcttatcct ttgtatttct tggaggggcg cttggagtgg cagtggcaga acgtatccgt
     6061 ctcgaagtgt agaaggatgc tgttatacaa ggatctgaag gcctattcat aggccgttat
     6121 ggaacatcat tccgatgatt gctcaaatga cgtttgtgaa gctcttgacc gggtgccggt
     6181 acttagcact acagctttaa acgtatgccc aatgaaccgt caggttcatc gggcataccc
     6241 gtatttccta gcccctccgg cctgcaggat ggggtaaggt gctcggattt cttctaatag
     6301 gtgtaggcct cgtactgcag atggtgatgc ttatactgaa ttttagtaaa agttataaac
     6361 aggatgagaa acgcgctgat tagcgggtga cggatgctgc aatcatcgac gctgacgagc
     6421 acgcttacag tgtggtccag gagatcggtg ctgatggggc aaaggtgagg tgccgccgaa
     6481 tcagggcccg acccccggga agtggacacg gaggtaggaa aggtgctaaa gcagctattc
     6541 aacccgttgg gaaacaaccc ccaggttaaa caacaaacac actgcaggtt ctctcatata
     6601 aaaccctgac taacctaaat ttttccgctt gcttatttct tagccttttt aggtggccat
     6661 aaaattaaaa gcactacaac aaccatgagg gcccagatca cataccgtgg agcctcccag
     6721 tgaaaggccg ctaagagtcc gagaacaccg aaggttgcca gaagcttttg cgcaagaatc
     6781 atttattcaa ccccaaacta atgccatcga acatttctca tggcccattc cctagtggat
     6841 ctgtaggtat gccctattaa gacactgatg tggaatgtgt tttccctgtt ttgtagggtt
     6901 gctgaatgat gtttgaagtg cttgtcgccc aggccctaga catgctgaga agtatttatc
     6961 tttgtcggac ctaaggatag aagacgaaat ctgccgcggg taaaaaaaga gggcttttcc
     7021 aaggcctcca tcatcagcaa gatccacatt aacttctatt gattgtcggt agtggactgg
     7081 caatttctga gtacttgcac tccagaactc ggtcattacc taacaaggca ttattagtcc
     7141 tcatcttccg aaaactcctt aagctcatcc tcagagaaaa aggatccaag tattttgtcg
     7201 accctttgca cttcgtcaat aacctcacga ctggccctgc cggtgttgat cagtccccag
     7261 agccacaata atttatccaa atgatccgct tgtaaatttg ttattgccgg tagccgacgg
     7321 gttacctttc ctaggttctc atcattaatt ggctcattga gatgagcgac atacgtcttt
     7381 actgattcat tgaatccgct aaagacgccc ttgagtcgct gcaatttttc agggttttcc
     7441 agcaggtttt tctctacctt gcgcagaatt tcattatccc tgtcgctcat gtcgtcttct
     7501 ggcgtacggt ctcttgacca acttccatta tccccccgaa cttttgcgcc aaactcaaca
     7561 attacagggg ctttagtttc tgggtctttc accgcatgaa gatttgggcc aaagtgattt
     7621 tttgaccatt gatcactggt gaagagcttc gctaaaatcc ggagccctga tgcttccgaa
     7681 ggtgctcggc cgccacgctc aattgccctt atggtcccct cggctaaatc cacccgggag
     7741 gctagttcgg ccacggaaag ccctcgatct tggcgggtga tctgaaccgt ccggccaaac
     7801 cacttcttac catgctcatt atcattggct acgagccaag tttcttttgg ctcagcctcc
     7861 agccattttc cgttgctcat agcccttacc ctacatggat ggacggggct gttacaagtt
     7921 atcgtttgac ttgttgcgtt tgttgtaatc atgtggcaaa gtggggcatg gcggaagtga
     7981 ttttccacta cgccccacat aaccagccct ggagggatag caatggaact attaaacaac
     8041 tttgccgacg aaactaagcg gaggaagatg cttaaagatc tcaatctggt gatcgagagc
     8101 ttcgggaaca tagcatctgt aattctcccg ctaattaagg gaaatggtcc catccaggga
     8161 aggtaatagg gcgccaaggg cctgtgcgca gcagcatggc aatcatgcga aaatgcagga
     8221 gtggggactg tgtaaatgcc ttcagacatc tcccttccag cacccttttg aaccgcgtcc
     8281 agcattttta gttgcccctg cattgacacg cgccttcttg agaggggcca ccccccactg
     8341 tcgtgtcagg ggttcggaag tgggtggccc atctgaaaaa actgtcactt taatgaattt
     8401 tgataacgtt tacatgactt aggtattatt acgggttaag tgacacgtca gttttttgcg
     8461 acctcgggta acgatttctg tatcaattgt cacgtaaacg atcgttttcg ttacgtatta
     8521 tttcgccctt caatcgacgt tttttagatg cctaggggac ttcacgtcct gagaaggagc
     8581 taatccgctg ccagtttcgc gtacaccgcc aaatcttgaa gcttcccatg gagattctca
     8641 ccgtggcgca tgatgccttc gaatcgacag ccggccactt cagctacatg ccgggacgca
     8701 gaattatcga ctgcggccct cacctcgaca cggttgatgc cattagcgaa gcagtgtttc
     8761 atgaggagtt ctagagcgcg ggcttgtagt ccgcgaccgc gcgcccaagg ggcggtgttg
     8821 tatccgatag aaacggaagg gatagacgca tctacgagac gggcttcaat attgccgcag
     8881 tagcgctccc caaactcgtc gcactgaaga gcaaacacaa tatgactggt ttgtctggtt
     8941 gcgaaatcga gagccatctc acgagtgtat tcgtaaggta cctgcgtata tttcttcatg
     9001 cgatcatcaa tggcgcacag ataaatatca tcggcatcac ttgctttcaa cccacgcaga
     9061 gtaagtgacc cgtcggaaag ctcagcgaat gggatgggcc aagtgaaatc attggtcatc
     9121 tatcccattc tagtggaatg tccgtgcatc ccatgccacc attcgaatag tgctcaaagt
     9181 cgccccacga agctgcgggt cacagacata cggtgagaag aacccggtgc atctgccaac
     9241 gggacatcca cagctcctcg acggccacat caacagcacc cactccgacc ttgccatgct
     9301 cagccaacca gacaatcatc cgtgcctgca tataggcctg tgaccagtca gaagcgatca
     9361 cgtgctcacg tttgccttcc aggatcaggt ccttggtggc cttggatggg atggtcgctg
     9421 tcatggttgt gatctcctta tatggttaac accacttcac aaccagactg gcagagagag
     9481 gggggtatac tgattgttca cccacgctca cacaccgccg gtgactgtcc ctgcctgacc
     9541 acctgaaccg aagtccttca gcccgaaccg acctacaagt tcgtgtagca accagacgac
     9601 gacgtgatct gggtatcgct cctgcccgaa aattttggtg gtgcccgcag caaaaaacaa
     9661 ccgatcaccc acggactatt ggcgggtcga ggctaagtgt tgcattttcc caacagtccg
     9721 ccgaagcctt cggtggacta tgtgagagct accttcccta cccaacacaa aactcccact
     9781 atccctagga ggaagaatac tgtgttcatt actccattgg catagcagag tttcaagcaa
     9841 aacttgccct tctcgatcgg gtagaagatt tggataggct gtttgttcag tagatcaagg
     9901 agaacatggg agataaaccc tgcggcaaag gctgccgtca gtggtgggca cagcaaccag
     9961 actcctgcgc tcaacgagac aagtccgagc aaagaatgtg tgaatgtccg atgcgatgta
    10021 aacctaccga atataaccag cgcaatcaga atggcagagc ctgcgatcaa tcgctgaata
    10081 ctgctttgca agacagagct aataattggt ccgtgggtga tcacatccac aatgagaaaa
    10141 accacggtcg gacctgaccc ccggatggta gacaccctga tgccagcatg atgctgggaa
    10201 aggtaatctg ccaccatgcc aagcaagacc tacacagagg agttcaagcg cgacgccgtc
    10261 acgctgtacg agaactcccc aggcgtctca atccacacca tcgggtcaag tccacccgag
    10321 tggtgtatct gcctttcgat aaaacaagca gcgtaacgat cttagggacc atcacgagct
    10381 aaatactgac cctggctcat gccacatcct tccggatgat ctcagaagta atatcgtccg
    10441 aatcgatgat gttcgccgtc atcatcgccc tggtctgctc caggctcgtc agtgacatgt
    10501 accgcttctg ctgaatccaa tcatcatgct gctccgctaa gactgc
//
