LOCUS       NZ_CP073653.1          28500 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP073653.1 Clostridium beijerinckii strain DSM 791 chromosome,
            complete genome.
ACCESSION   NZ_CP073653
VERSION     NZ_CP073653.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:43:32
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 309142
            Orig. end    :: 337642
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..960)
                     /locus_tag="ctg1_271"
                     /transl_table=11
                     /translation="MLKGTLPPRNISYKRFFKNKTSLSILIFSLLFVMFSIYLILHNIS
                     YKNSIASNHSSDNTSIDENHVESKNGLEKDPSNIEQNTIQNERSFNGSNLITDNRGVPV
                     LYYHSVRETAENEVTITPENLRMQLEYIKNQGYITLTLDELKNYLLNNSPIPEKSIVIT
                     FDDGYMDNYYNAFPILKNLNMVATIFCITSDLDGSYYLSKEAIKEMSDYGIDIESHTVS
                     HPKLNQLPYDKQLNELKESKETLESITGKKIEAIAYPFGDFNDDSVTAAKNSGYTLAFT
                     TKRGLSDRDDNILKLDRIYISSKYDMNTFKEVLAQTKK"
     cand_cluster    1..28500
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="neighbouring"
                     /product="cyclic-lactone-autoinducer"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     region          1..28500
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="cyclic-lactone-autoinducer"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="(TIGR04223 or AgrB)"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     protocluster    1..19001
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[318140:318822]"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      8999..9680
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..19001
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     PFAM_domain     complement(127..498)
                     /aSDomain="Polysacc_deac_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01522.23"
                     /description="Polysaccharide deacetylase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_271_0001"
                     /evalue="1.30E-30"
                     /label="ctg1_271"
                     /locus_tag="ctg1_271"
                     /protein_end="278"
                     /protein_start="154"
                     /score="106.0"
                     /tool="antismash"
                     /translation="IPEKSIVITFDDGYMDNYYNAFPILKNLNMVATIFCITSDLDGSY
                     YLSKEAIKEMSDYGIDIESHTVSHPKLNQLPYDKQLNELKESKETLESITGKKIEAIAY
                     PFGDFNDDSVTAAKNSGYTL"
     CDS             1367..2122
                     /locus_tag="ctg1_272"
                     /transl_table=11
                     /translation="MGIIANITGLLIVSSMLSTACPQEMFITNKMQSESKIKIVDKSIT
                     KNLNYLKLDINMPQLVGENDEKRINLINNVINQDILPRAEESEKTAKEYFGEKGQETPR
                     FPYEIYSRYTTSEDNNQILSLYNDYYEFLGGAHGMTTRTSYTIDKKKEALLTLKELFSE
                     GYNYSDIINKEIENQIKENPENYFDSGNVFKGISENQSFYIRDDNLVIYYQLYDIAPYV
                     FGIPEFKIPLKLFDKDFVYYKNWDSGSKK"
     PFAM_domain     1499..1786
                     /aSDomain="PdaC"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13739.8"
                     /description="Deacetylase PdaC"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_272_0002"
                     /evalue="1.90E-20"
                     /label="ctg1_272"
                     /locus_tag="ctg1_272"
                     /protein_end="140"
                     /protein_start="44"
                     /score="73.8"
                     /tool="antismash"
                     /translation="TKNLNYLKLDINMPQLVGENDEKRINLINNVINQDILPRAEESEK
                     TAKEYFGEKGQETPRFPYEIYSRYTTSEDNNQILSLYNDYYEFLGGAHGMT"
     PFAM_domain     1838..2062
                     /aSDomain="DUF3298"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF11738.10"
                     /description="Protein of unknown function (DUF3298)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_272_0003"
                     /evalue="1.00E-19"
                     /label="ctg1_272"
                     /locus_tag="ctg1_272"
                     /protein_end="232"
                     /protein_start="157"
                     /score="71.4"
                     /tool="antismash"
                     /translation="KELFSEGYNYSDIINKEIENQIKENPENYFDSGNVFKGISENQSF
                     YIRDDNLVIYYQLYDIAPYVFGIPEFKIPL"
     CDS             complement(2363..3409)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF06968"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_273"
                     /sec_met_domain="PF06968 (E-value: 8e-06, bitscore: 24.2,
                     seeds: 824, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 2.5e-20, bitscore: 71.7,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKIIEKAKITHDLNKDEILELLQNDDINEELFKAADEVRQKYLG
                     DYVHLRGLIEFTNICKRNCLYCGLRRDNKNLERYRLTEEEILDFAKKAVSYGYKTLVLQ
                     GGEDDYFTKERMTNIVKEIKKLNVALTLSLGEKTYEEYKAFKEAGADRYLIRIETTDKK
                     LYEDMDPNMSFEERLNCLKNLRDLGYEVGSGILVGLPNQTLESIASDILFFKEINADMI
                     GIGPFIPNEDTPLKDAQGGNLTLALKVMALTRLILPDINIPATTAMESLTPNGRIVALQ
                     SGANVVMPNVTEGEYRKLYALYPGKICTGDTPAHCRGCITGKVTGIGRIISDGYGFRGN
                     QNTSAYNN"
     aSDomain        complement(2414..3397)
                     /aSDomain="TIGR03956"
                     /aSTool="tigrfam"
                     /description="rSAM_HydE: [FeFe] hydrogenase H-cluster
                     radical SAM maturase HydE"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_273_0001"
                     /evalue="1.20E-119"
                     /identifier="TIGR03956"
                     /label="ctg1_273"
                     /locus_tag="ctg1_273"
                     /protein_end="332"
                     /protein_start="4"
                     /score="397.5"
                     /tool="antismash"
                     /translation="IEKAKITHDLNKDEILELLQNDDINEELFKAADEVRQKYLGDYVH
                     LRGLIEFTNICKRNCLYCGLRRDNKNLERYRLTEEEILDFAKKAVSYGYKTLVLQGGED
                     DYFTKERMTNIVKEIKKLNVALTLSLGEKTYEEYKAFKEAGADRYLIRIETTDKKLYED
                     MDPNMSFEERLNCLKNLRDLGYEVGSGILVGLPNQTLESIASDILFFKEINADMIGIGP
                     FIPNEDTPLKDAQGGNLTLALKVMALTRLILPDINIPATTAMESLTPNGRIVALQSGAN
                     VVMPNVTEGEYRKLYALYPGKICTGDTPAHCRGCITGKVTGIGRIIS"
     PFAM_domain     complement(2489..2731)
                     /aSDomain="BATS"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06968.15"
                     /description="Biotin and Thiamin Synthesis associated
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_273_0005"
                     /evalue="3.90E-06"
                     /label="ctg1_273"
                     /locus_tag="ctg1_273"
                     /protein_end="307"
                     /protein_start="226"
                     /score="27.0"
                     /tool="antismash"
                     /translation="FIPNEDTPLKDAQGGNLTLALKVMALTRLILPDINIPATTAMESL
                     TPNGRIVALQSGANVVMPNVTEGEYRKLYALYPGKI"
     PFAM_domain     complement(2786..3250)
                     /aSDomain="Radical_SAM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04055.23"
                     /description="Radical SAM superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_273_0004"
                     /evalue="4.40E-20"
                     /label="ctg1_273"
                     /locus_tag="ctg1_273"
                     /protein_end="208"
                     /protein_start="53"
                     /score="72.8"
                     /tool="antismash"
                     /translation="IEFTNICKRNCLYCGLRRDNKNLERYRLTEEEILDFAKKAVSYGY
                     KTLVLQGGEDDYFTKERMTNIVKEIKKLNVALTLSLGEKTYEEYKAFKEAGADRYLIRI
                     ETTDKKLYEDMDPNMSFEERLNCLKNLRDLGYEVGSGILVGLPNQTLESIA"
     CDS             3934..6516
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017:aldehyde dehydrogenase (Score: 75.2; E-value:
                     5.8e-23)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_274"
                     /transl_table=11
                     /translation="MRVTNPEELTKRMEQIREAQREFAKFSQEDVDEIFRQAAMAANDA
                     RITLAKMAVEESGMGIVEDKVIKNHFAAEYIYNQYKDTKTCGVIERDEMFGITHIAEPI
                     GVIAAIVPTTNPTSTAIFKTLIALKTRNGIIISPHPRAKNSTIAAAKIVLEAAERAGAP
                     KGIIGWIDEPSIELSRNVMAESDIILATGGPGMVRAAYSSGKPAIGVGAGNTPAIIDDT
                     AHIKMVVNSILLSKTFDNGVVCASEQSIIAMESVYDEVLKELDERGAYILRGEEIDKVR
                     SIILDSKGSLNSEIVGQSAYKIAKMAGVEISEAAKVLIGEVESPELEEPFSHEKLSPIL
                     GMYKAKTFDDALRLASRMIELGGFGHTSILYTNQMESVDRIEKFGVAMKTARTLINMPA
                     PQGAIGDIYNFKLAPSLTLGCGSWGGNSISENVGPKHLINVKRIAERRENILWFRVPDK
                     IYFKFGCLPIALEELNAMKKKRAFIVTDRVLFDLGYTHKITDILSENHIEYKIFSDVEP
                     DPTLKAANLGADAMRDFNPDVIIAIGGGSPMDAAKIMWVMYEHPDVRFEDLAMRFMDIR
                     KRVYEFPPMGEKAILVAIPTSAGTGSEVTPFAVITDQQTGVKYPLADYALTPNMAIIDA
                     ELMMSMPKGLTAASGIDALVHAIEAYVSVLASEYTNGLALEAIRLTFKYLPDAYNGGTT
                     NIKAREKMAHASSVAGMAFANAFLGICHSMAHKLGAFHHVPHGIANALLIDEAIRFNAT
                     DAPRKQAAFPQYKYPNAGWRYARIADYLNLGGNTEEEKVELLIKAIDDLKAKVGIPKSI
                     KEFGVSEEKFYASMDEMVEQAFDDQCTGANPRYPLMSEIKEMYIKSYD"
     PFAM_domain     3946..5124
                     /aSDomain="Aldedh"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00171.24"
                     /description="Aldehyde dehydrogenase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_274_0006"
                     /evalue="2.70E-24"
                     /label="ctg1_274"
                     /locus_tag="ctg1_274"
                     /protein_end="397"
                     /protein_start="4"
                     /score="85.6"
                     /tool="antismash"
                     /translation="NPEELTKRMEQIREAQREFAKFSQEDVDEIFRQAAMAANDARITL
                     AKMAVEESGMGIVEDKVIKNHFAAEYIYNQYKDTKTCGVIERDEMFGITHIAEPIGVIA
                     AIVPTTNPTSTAIFKTLIALKTRNGIIISPHPRAKNSTIAAAKIVLEAAERAGAPKGII
                     GWIDEPSIELSRNVMAESDIILATGGPGMVRAAYSSGKPAIGVGAGNTPAIIDDTAHIK
                     MVVNSILLSKTFDNGVVCASEQSIIAMESVYDEVLKELDERGAYILRGEEIDKVRSIIL
                     DSKGSLNSEIVGQSAYKIAKMAGVEISEAAKVLIGEVESPELEEPFSHEKLSPILGMYK
                     AKTFDDALRLASRMIELGGFGHTSILYTNQMESVDRIEKFGVAMKTARTLINM"
     PFAM_domain     5299..6474
                     /aSDomain="Fe-ADH"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00465.21"
                     /description="Iron-containing alcohol dehydrogenase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_274_0007"
                     /evalue="3.90E-117"
                     /label="ctg1_274"
                     /locus_tag="ctg1_274"
                     /protein_end="847"
                     /protein_start="455"
                     /score="391.2"
                     /tool="antismash"
                     /translation="PDKIYFKFGCLPIALEELNAMKKKRAFIVTDRVLFDLGYTHKITD
                     ILSENHIEYKIFSDVEPDPTLKAANLGADAMRDFNPDVIIAIGGGSPMDAAKIMWVMYE
                     HPDVRFEDLAMRFMDIRKRVYEFPPMGEKAILVAIPTSAGTGSEVTPFAVITDQQTGVK
                     YPLADYALTPNMAIIDAELMMSMPKGLTAASGIDALVHAIEAYVSVLASEYTNGLALEA
                     IRLTFKYLPDAYNGGTTNIKAREKMAHASSVAGMAFANAFLGICHSMAHKLGAFHHVPH
                     GIANALLIDEAIRFNATDAPRKQAAFPQYKYPNAGWRYARIADYLNLGGNTEEEKVELL
                     IKAIDDLKAKVGIPKSIKEFGVSEEKFYASMDEMVEQAFDDQCTGANPRYPL"
     CDS             7028..7786
                     /locus_tag="ctg1_275"
                     /transl_table=11
                     /translation="LYSVILVEDDSTQRGILKTMINSIDESIKIYEADSESVALEIIKN
                     SDINMFFIDIGLKESSGLDLAMDIRGIPKYEFREIVFLTTHVEYMLQAFKQTHCYDYIL
                     KPYSKDDVQSMLNKLIGKDINNLSNEIGDLSRELVIRIRTGVFIRVKIHDILFIEVKGR
                     DCEVNTISQVYTYSNISLKKILGLIDCEHIVQSHKSFAVNKNYIFKVERLDSRLSTIYF
                     SKHSKTALLGYKFKNNIISEFKQVGRYYVK"
     PFAM_domain     7037..7375
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_275_0008"
                     /evalue="8.80E-16"
                     /label="ctg1_275"
                     /locus_tag="ctg1_275"
                     /protein_end="116"
                     /protein_start="3"
                     /score="58.2"
                     /tool="antismash"
                     /translation="VILVEDDSTQRGILKTMINSIDESIKIYEADSESVALEIIKNSDI
                     NMFFIDIGLKESSGLDLAMDIRGIPKYEFREIVFLTTHVEYMLQAFKQTHCYDYILKPY
                     SKDDVQSML"
     PFAM_domain     7466..7708
                     /aSDomain="LytTR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04397.17"
                     /description="LytTr DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_275_0009"
                     /evalue="1.50E-08"
                     /label="ctg1_275"
                     /locus_tag="ctg1_275"
                     /protein_end="227"
                     /protein_start="146"
                     /score="34.9"
                     /tool="antismash"
                     /translation="FIRVKIHDILFIEVKGRDCEVNTISQVYTYSNISLKKILGLIDCE
                     HIVQSHKSFAVNKNYIFKVERLDSRLSTIYFSKHSK"
     CDS             7776..9023
                     /locus_tag="ctg1_276"
                     /transl_table=11
                     /translation="MLSNFIVNSLDAMNIIYLWVVLNKRNSSWHRFLFTVIICSSSVTT
                     VEYFKLNFVISYILMTITIKIIYKRELKDIVLQFFLVLFTEMSFQLVISTIVYRIIYGE
                     FIKGIILELITLVSIAIFSKLNSNNKINFEKINNDISMYLILTFSIDVIIFKIILIYDD
                     TLISNNLPITALIVSILVSSQILIYNYIIRGMKENEKLKISREYNEVINEIVQEIKQRQ
                     HDFVNYKNTIRGIVEIVDEDKIGQAIRNYIKDEDIYDDKINELVYIDNVIIRSIVYRNM
                     CKAKKNNINFQYEIENNVLDNILSYNEISNLLNNLLNNAFEEVMKDDCIKKNIEIKILK
                     EGETHYLIVKNNLSNANNVNINDMLTRGYSTKNTGTRGYGLYNVEQIITSHKGCLEVKV
                     ESKEIILNIYFNNSSG"
     protocluster    7776..28500
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[326694:328143](+)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      17553..19001
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="2"
     cand_cluster    7776..28500
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="2"
                     /tool="antismash"
     PFAM_domain     8694..9005
                     /aSDomain="HATPase_c_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14501.8"
                     /description="GHKL domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_276_0010"
                     /evalue="5.20E-11"
                     /label="ctg1_276"
                     /locus_tag="ctg1_276"
                     /protein_end="410"
                     /protein_start="306"
                     /score="42.4"
                     /tool="antismash"
                     /translation="NEISNLLNNLLNNAFEEVMKDDCIKKNIEIKILKEGETHYLIVKN
                     NLSNANNVNINDMLTRGYSTKNTGTRGYGLYNVEQIITSHKGCLEVKVESKEIILNIYF
                     "
     CDS             complement(8999..9118)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_277"
                     /sec_met_domain="TIGR04223 (E-value: 2.1e-06, bitscore:
                     25.9, seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQKSLNIFSALLIKFFNLVSNTSCAGYIGEPDYPEELLK"
     aSDomain        complement(9002..9112)
                     /aSDomain="TIGR04223"
                     /aSTool="tigrfam"
                     /description="quorum_AgrD: cyclic lactone autoinducer
                     peptide"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_277_0002"
                     /evalue="1.80E-06"
                     /identifier="TIGR04223"
                     /label="ctg1_277"
                     /locus_tag="ctg1_277"
                     /protein_end="39"
                     /protein_start="2"
                     /score="25.9"
                     /tool="antismash"
                     /translation="KSLNIFSALLIKFFNLVSNTSCAGYIGEPDYPEELLK"
     CDS             complement(9078..9680)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_278"
                     /sec_met_domain="AgrB (E-value: 4.3e-35, bitscore: 119.0,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINSVATFLTEYLGKNNNSLTEKDLLKIQYSLQVILGDLSKSVII
                     LSIFLSLKQLPFFFLIFVILNSTRIFMGGIHCKTFNSCLICSIIYFLIILLFSILSPKL
                     NIYFYIIFFIISFIITSVYAPCRNEKRPVKNKKILKILSLISLTFWCILFFKLRDTQVC
                     NCIFLSLLLEVIQVIIINLKGGVYNAKITKHFFSLTN"
     PFAM_domain     complement(9150..9659)
                     /aSDomain="AgrB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04647.17"
                     /description="Accessory gene regulator B"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_278_0011"
                     /evalue="1.30E-34"
                     /label="ctg1_278"
                     /locus_tag="ctg1_278"
                     /protein_end="177"
                     /protein_start="7"
                     /score="119.3"
                     /tool="antismash"
                     /translation="FLTEYLGKNNNSLTEKDLLKIQYSLQVILGDLSKSVIILSIFLSL
                     KQLPFFFLIFVILNSTRIFMGGIHCKTFNSCLICSIIYFLIILLFSILSPKLNIYFYII
                     FFIISFIITSVYAPCRNEKRPVKNKKILKILSLISLTFWCILFFKLRDTQVCNCIFLSL
                     LLEVIQV"
     CDS             complement(9737..11101)
                     /locus_tag="ctg1_279"
                     /transl_table=11
                     /translation="MKRTIKFYVFCFLGIFLSIFIIYAIINLRKNIIIINKTIYSSSFP
                     KSNFKSTYNSKINFSDTPVAEINGVNLNILSETNIANVPMLLKSQRYYIPLSFICDKLS
                     YTLYVSVNEILLYGNNNKISLTKDCYYKNSNSGSLRGNLIKYNGTYYISISDIEQLFDL
                     VAVFDFKNNSISLINSNVKAPEEPYILYSDKIALMRWEDFACGGSNFTDTNQTKIKCMA
                     DLLYSKGVKFHVSWIPRFKSPEDNIDNDLLKNNNIVNVGFVNLLDYLINRGAKIGLHGY
                     THQHGNEESGTGEEMSKDVNNTIPETRSIVENGIDTASALNIPISYFESPHYQKTQLQR
                     KVIEDYFQYIYESFDGSQSNIYKSDDYHLFVPTPLGYVHDSNPSSIIDGLNNYNPYILH
                     SFYYHPFVELKYINFDTTNNKLNVTYDENSPLQQIVRTLKTDKYTMVHIDELINK"
     PFAM_domain     complement(9791..10516)
                     /aSDomain="DUF2334"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10096.11"
                     /description="Uncharacterized protein conserved in bacteria
                     (DUF2334)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_279_0012"
                     /evalue="6.00E-54"
                     /label="ctg1_279"
                     /locus_tag="ctg1_279"
                     /protein_end="437"
                     /protein_start="195"
                     /score="183.0"
                     /tool="antismash"
                     /translation="ALMRWEDFACGGSNFTDTNQTKIKCMADLLYSKGVKFHVSWIPRF
                     KSPEDNIDNDLLKNNNIVNVGFVNLLDYLINRGAKIGLHGYTHQHGNEESGTGEEMSKD
                     VNNTIPETRSIVENGIDTASALNIPISYFESPHYQKTQLQRKVIEDYFQYIYESFDGSQ
                     SNIYKSDDYHLFVPTPLGYVHDSNPSSIIDGLNNYNPYILHSFYYHPFVELKYINFDTT
                     NNKLNVTYDENSPLQQIVRT"
     CDS             complement(11203..11493)
                     /locus_tag="ctg1_280"
                     /transl_table=11
                     /translation="MINSIKFLLIISMTLCGALGGTFFKKSSSKSNKINGYLILGMCLY
                     GMGSILNIILLKYIQLTILLPCNAITYIWTALIAKYIFNENIIYWEYHLLD"
     CDS             complement(11483..11800)
                     /locus_tag="ctg1_281"
                     /transl_table=11
                     /translation="MKIRIGIMFILISAFLTATGQLLWKIGINNIKFLPLGFLFYGFGS
                     IFMIKSFEKEKLVVVYPIMCISYVISMFYGNLFLNETITPNKVLAVILIILGVSFNSYD
                     K"
     PFAM_domain     complement(11495..11791)
                     /aSDomain="EamA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00892.22"
                     /description="EamA-like transporter family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_281_0013"
                     /evalue="5.90E-08"
                     /label="ctg1_281"
                     /locus_tag="ctg1_281"
                     /protein_end="102"
                     /protein_start="3"
                     /score="33.1"
                     /tool="antismash"
                     /translation="RIGIMFILISAFLTATGQLLWKIGINNIKFLPLGFLFYGFGSIFM
                     IKSFEKEKLVVVYPIMCISYVISMFYGNLFLNETITPNKVLAVILIILGVSFNS"
     CDS             complement(11797..12417)
                     /locus_tag="ctg1_282"
                     /transl_table=11
                     /translation="MKIPFAIFDVDHTLINGDSMFLMLFFAISKKVRLIFYTPMIFLKI
                     LLCLFKIIDIKNVKESIYAPIKYLNEKQLEEFYDKVLLKKINEKVMSKLNFHKDQGCHI
                     LLVSASPEMYLHYFLKNSSIDTIIGTKLKMLDGKCTNKIHGKNCKGIEKVHRIKQYLNE
                     NNLEIDFDNSFAYSDSLSDKPMLSLVKNRYKVNKNGLEIEEFI"
     aSDomain        complement(11827..12402)
                     /aSDomain="TIGR01490"
                     /aSTool="tigrfam"
                     /description="HAD-SF-IB-hyp1: HAD hydrolase, family IB"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_282_0003"
                     /evalue="6.90E-39"
                     /identifier="TIGR01490"
                     /label="ctg1_282"
                     /locus_tag="ctg1_282"
                     /protein_end="197"
                     /protein_start="5"
                     /score="132.1"
                     /tool="antismash"
                     /translation="AIFDVDHTLINGDSMFLMLFFAISKKVRLIFYTPMIFLKILLCLF
                     KIIDIKNVKESIYAPIKYLNEKQLEEFYDKVLLKKINEKVMSKLNFHKDQGCHILLVSA
                     SPEMYLHYFLKNSSIDTIIGTKLKMLDGKCTNKIHGKNCKGIEKVHRIKQYLNENNLEI
                     DFDNSFAYSDSLSDKPMLSLVKNRYKVNK"
     aSDomain        complement(11851..12402)
                     /aSDomain="TIGR01488"
                     /aSTool="tigrfam"
                     /description="HAD-SF-IB: HAD phosphoserine phosphatase-like
                     hydrolase, family IB"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_282_0004"
                     /evalue="1.90E-27"
                     /identifier="TIGR01488"
                     /label="ctg1_282"
                     /locus_tag="ctg1_282"
                     /protein_end="189"
                     /protein_start="5"
                     /score="94.3"
                     /tool="antismash"
                     /translation="AIFDVDHTLINGDSMFLMLFFAISKKVRLIFYTPMIFLKILLCLF
                     KIIDIKNVKESIYAPIKYLNEKQLEEFYDKVLLKKINEKVMSKLNFHKDQGCHILLVSA
                     SPEMYLHYFLKNSSIDTIIGTKLKMLDGKCTNKIHGKNCKGIEKVHRIKQYLNENNLEI
                     DFDNSFAYSDSLSDKPMLSLV"
     PFAM_domain     complement(11860..12402)
                     /aSDomain="HAD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12710.9"
                     /description="haloacid dehalogenase-like hydrolase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_282_0014"
                     /evalue="5.50E-30"
                     /label="ctg1_282"
                     /locus_tag="ctg1_282"
                     /protein_end="186"
                     /protein_start="5"
                     /score="105.3"
                     /tool="antismash"
                     /translation="AIFDVDHTLINGDSMFLMLFFAISKKVRLIFYTPMIFLKILLCLF
                     KIIDIKNVKESIYAPIKYLNEKQLEEFYDKVLLKKINEKVMSKLNFHKDQGCHILLVSA
                     SPEMYLHYFLKNSSIDTIIGTKLKMLDGKCTNKIHGKNCKGIEKVHRIKQYLNENNLEI
                     DFDNSFAYSDSLSDKPML"
     CDS             complement(12433..13293)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ubiA"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_283"
                     /sec_met_domain="ubiA (E-value: 1.7e-19, bitscore: 68.5,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNFKYSIKLLRPKQWVKNLFVFGPIIFSNNLMNLELLKRNFITF
                     ISFCCISSAIYILNDIVDRESDKKHPIKCNRPIASGKISLLQASIVGILLCLISLSLAI
                     IQDKFIFIIICLYVINNLAYSFKLKNIFLIDILSISLGFILRVLSGGISTTVQVSRWII
                     LCTLFLSLFLGFGKRRNEIIVLGENASSHRQNLSQYTENLLDKFITITLTCTIMSYSIY
                     CILGSYNDNFIWTSIFIIFGVLRYYYLMYSKEVGGNPAEIVLKDKQLFNCILLWGFTCI
                     AILSI"
     PFAM_domain     complement(12535..13170)
                     /aSDomain="UbiA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01040.20"
                     /description="UbiA prenyltransferase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_283_0015"
                     /evalue="3.50E-25"
                     /label="ctg1_283"
                     /locus_tag="ctg1_283"
                     /protein_end="253"
                     /protein_start="41"
                     /score="88.8"
                     /tool="antismash"
                     /translation="FITFISFCCISSAIYILNDIVDRESDKKHPIKCNRPIASGKISLL
                     QASIVGILLCLISLSLAIIQDKFIFIIICLYVINNLAYSFKLKNIFLIDILSISLGFIL
                     RVLSGGISTTVQVSRWIILCTLFLSLFLGFGKRRNEIIVLGENASSHRQNLSQYTENLL
                     DKFITITLTCTIMSYSIYCILGSYNDNFIWTSIFIIFGVLRYYYLMYSK"
     CDS             complement(13286..14782)
                     /locus_tag="ctg1_284"
                     /transl_table=11
                     /translation="MDNIKNMFNKFLNLSLKVLFLPPIIGSIIYLYLKKDDNNLLFSIF
                     CFIISIMLIGITYYCLKNNYKHLSIITIILICAFVIRLLWFYNIDSIPISDFNRMFICA
                     EDFAHGSTYMFRDYSYFARFPHMSMTVIYFSLIIRVFSNPLVAIRFINVIFSMLNIILL
                     FFISKEIFKDKTKSIWVLLLSSIYPPMITYNNVYCSENLAIPLLLLSVLMFFKAINGYI
                     KNKLLFFLISGLYLSAMQLFRPLGYIMIVAYTMYIFLYFKEKIKLKIIKSLLIILMFII
                     PYVIVSYTLIGLNITENPLWSPMEPISTSVLKGTNIYSGGGWNEEDFNLIDKYSEDYSN
                     LDKAAKEVITQRLITTPKIELLCFFVFKYAKQWCIGDFGGVYWSQLGLNEAYNKEHYLD
                     IMGKNEGRDLIKLSNDMQIYTQLFYITILILTYIGLYKNKKNVNYKIDFFYIMFCGLAI
                     QCLLTEAQDRYSYPFSWIFIILAITAFNNNTVNSNGGKNE"
     PFAM_domain     complement(13937..14380)
                     /aSDomain="PMT_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13231.8"
                     /description="Dolichyl-phosphate-mannose-protein
                     mannosyltransferase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_284_0016"
                     /evalue="1.40E-09"
                     /label="ctg1_284"
                     /locus_tag="ctg1_284"
                     /protein_end="282"
                     /protein_start="134"
                     /score="38.5"
                     /tool="antismash"
                     /translation="SLIIRVFSNPLVAIRFINVIFSMLNIILLFFISKEIFKDKTKSIW
                     VLLLSSIYPPMITYNNVYCSENLAIPLLLLSVLMFFKAINGYIKNKLLFFLISGLYLSA
                     MQLFRPLGYIMIVAYTMYIFLYFKEKIKLKIIKSLLIILMFIIP"
     CDS             14968..15144
                     /locus_tag="ctg1_285"
                     /transl_table=11
                     /translation="VVNYIKLFDIIIEFINWDTLKHSEFKLNADNKISQLFTKDHLKSM
                     IYIYNISYLTTNL"
     CDS             15418..17172
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 291.1; E-value: 3e-88)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_286"
                     /transl_table=11
                     /translation="MNGKKEDMQILNNLLKLFKPFKLKIILVIICITMSAGLSILTPTV
                     NQRLMDEGLIAKNLKIIITYSICNLILIMIIQGLGIIETKYRSYIENLLSYNLEEQAFT
                     HTLKMKMSFFLSTNYAEIMNNLKIDIGNISQIVDQSTFYIVTSIFRIIVGIIGLITIDW
                     RLSILVLIATPLRYLIVKYLAKKRRNLFERFINSYEDFSGWYGDTIGGIKEIKIWGLEL
                     SKTGQFIKKQKEIIKQNIRMSYLAKANEISETVFTQAITSLIYVIGGYLIIGNSLTVGR
                     LFAFIAYSSYVTGPIFAIMNIGYSFAGIMPSAKRYFEFINTETEDICRNYISKKLNSSE
                     VLGNIEFKNVEFSYNDKECVLKNISFKINAGEKVAIIGSNGSGKTTVINLILRFLTPDS
                     GSILLDGNDINSFKLKDYRKLISVVSQDVYLFNSSIRENIMLNSKKTDIEMNSAVKKSG
                     AYRFIEEMPDKYESIVGQRGGTLSGGERQKIAMARAFIRDSKILVLDEATANYDMEAEY
                     QVNNIIKESYKDKTIIIISHKPDILAKVDKIIVINNGVIEDIGNHIDLYNRSEFYRLMV
                     NIPLDEII"
     PFAM_domain     15490..16302
                     /aSDomain="ABC_membrane"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00664.25"
                     /description="ABC transporter transmembrane region"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_286_0017"
                     /evalue="6.50E-30"
                     /label="ctg1_286"
                     /locus_tag="ctg1_286"
                     /protein_end="295"
                     /protein_start="24"
                     /score="104.8"
                     /tool="antismash"
                     /translation="IILVIICITMSAGLSILTPTVNQRLMDEGLIAKNLKIIITYSICN
                     LILIMIIQGLGIIETKYRSYIENLLSYNLEEQAFTHTLKMKMSFFLSTNYAEIMNNLKI
                     DIGNISQIVDQSTFYIVTSIFRIIVGIIGLITIDWRLSILVLIATPLRYLIVKYLAKKR
                     RNLFERFINSYEDFSGWYGDTIGGIKEIKIWGLELSKTGQFIKKQKEIIKQNIRMSYLA
                     KANEISETVFTQAITSLIYVIGGYLIIGNSLTVGRLFAFIAYSSYVTGP"
     PFAM_domain     16498..16944
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_286_0018"
                     /evalue="2.80E-36"
                     /label="ctg1_286"
                     /locus_tag="ctg1_286"
                     /protein_end="509"
                     /protein_start="360"
                     /score="125.1"
                     /tool="antismash"
                     /translation="LKNISFKINAGEKVAIIGSNGSGKTTVINLILRFLTPDSGSILLD
                     GNDINSFKLKDYRKLISVVSQDVYLFNSSIRENIMLNSKKTDIEMNSAVKKSGAYRFIE
                     EMPDKYESIVGQRGGTLSGGERQKIAMARAFIRDSKILVLDEATA"
     aSDomain        17269..17364
                     /aSDomain="TIGR04065"
                     /aSTool="tigrfam"
                     /description="ocin_CLI_3235: putative bacteriocin
                     precursor, CLI_3235 family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_287_0005"
                     /evalue="1.60E-08"
                     /identifier="TIGR04065"
                     /label="ctg1_287"
                     /locus_tag="ctg1_287"
                     /protein_end="32"
                     /protein_start="0"
                     /score="32.6"
                     /tool="antismash"
                     /translation="MRKLGKKNYEIIETVEAYEDDCYAQQDCYKSC"
     CDS             17269..17445
                     /locus_tag="ctg1_287"
                     /transl_table=11
                     /translation="MRKLGKKNYEIIETVEAYEDDCYAQQDCYKSCKDRVARKSLNDKL
                     FNEAHYGDGGFHW"
     CDS             17553..19001
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Other_Sactipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_288"
                     /sec_met_domain="PF04055 (E-value: 1.6e-11, bitscore: 43.1,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 1.9e-09, bitscore: 36.1,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="Other_Sactipeptide_rSAM_RRE (E-value:
                     2.1e-18, bitscore: 64.8, seeds: 13, tool:
                     rule-based-clusters)"
                     /transl_table=11
                     /translation="MYMNSKPLIKLFRTNDKYYMYDTNKNTILNISNKQYNSLENYMKD
                     DIDHYIDSEEINEFYKEGFLSSNRVKDIESPYNGVLPSYLDSNVGMIILQVTQQCNFRC
                     EYCVYSGNYLNRTHSSKKMDISMAFKGIDFLINHSRNLSKIDVSFYGGEPLLEFDFIKQ
                     CIDYAEKKAEGKKVTFYMTTNGSLLTDEVVEFLYKHDVMLTISLDGPKEIHDKHRKFAF
                     NNCGTFDKVIKNVMNIEKKFPQYINNILFNVVIDTQNDFSCIDKFFLDYESIKDIDMIS
                     GVISGNNIKSIIEMNEDYYLKVEYELFRIFYYLLRKHNTKNCSRIVIERYSQILKLSEE
                     LMPQKMLSEKAHPSGPCIPGAQRLFMNVDGFFYPCERVSETSELMQIGHIDTGFDIKKV
                     TSIFNIGKLNEDDCKNCWAIRLCGVCAGALDMDTDEKEFSKKKREECCKNVKASLEEKF
                     KNYCFLKEFGHSFDKNEEMTVFND"
     aSDomain        17574..18959
                     /aSDomain="TIGR04068"
                     /aSTool="tigrfam"
                     /description="rSAM_ocin_clost: Cys-rich peptide radical SAM
                     maturase CcpM"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_288_0006"
                     /evalue="2.90E-179"
                     /identifier="TIGR04068"
                     /label="ctg1_288"
                     /locus_tag="ctg1_288"
                     /protein_end="469"
                     /protein_start="7"
                     /score="594.7"
                     /tool="antismash"
                     /translation="LIKLFRTNDKYYMYDTNKNTILNISNKQYNSLENYMKDDIDHYID
                     SEEINEFYKEGFLSSNRVKDIESPYNGVLPSYLDSNVGMIILQVTQQCNFRCEYCVYSG
                     NYLNRTHSSKKMDISMAFKGIDFLINHSRNLSKIDVSFYGGEPLLEFDFIKQCIDYAEK
                     KAEGKKVTFYMTTNGSLLTDEVVEFLYKHDVMLTISLDGPKEIHDKHRKFAFNNCGTFD
                     KVIKNVMNIEKKFPQYINNILFNVVIDTQNDFSCIDKFFLDYESIKDIDMISGVISGNN
                     IKSIIEMNEDYYLKVEYELFRIFYYLLRKHNTKNCSRIVIERYSQILKLSEELMPQKML
                     SEKAHPSGPCIPGAQRLFMNVDGFFYPCERVSETSELMQIGHIDTGFDIKKVTSIFNIG
                     KLNEDDCKNCWAIRLCGVCAGALDMDTDEKEFSKKKREECCKNVKASLEEKFKNYCFLK
                     EFGH"
     PFAM_domain     17829..18206
                     /aSDomain="Fer4_12"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13353.8"
                     /description="4Fe-4S single cluster domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_288_0019"
                     /evalue="2.00E-09"
                     /label="ctg1_288"
                     /locus_tag="ctg1_288"
                     /protein_end="218"
                     /protein_start="92"
                     /score="38.2"
                     /tool="antismash"
                     /translation="ILQVTQQCNFRCEYCVYSGNYLNRTHSSKKMDISMAFKGIDFLIN
                     HSRNLSKIDVSFYGGEPLLEFDFIKQCIDYAEKKAEGKKVTFYMTTNGSLLTDEVVEFL
                     YKHDVMLTISLDGPKEIHDKHR"
     CDS             19023..20141
                     /locus_tag="ctg1_289"
                     /transl_table=11
                     /translation="MKNEYKTMIYPFDVESAPLIRHSNFIDNHNIVNIISPNGWGLCGK
                     DAGHTDGGQPVGIIIDSDFDKALENCDTVFFTDSSMKIDLHKFVYPKIIKAAQSSKNII
                     CTIKLENEIIDKVSNICNQNNMFFKYFTNESNSMISPPTEKIYQINTPVVLVFGLSERT
                     NKFEIQLNLRENLDEMGYKVSQIGTRHYCELMGFHSFPKFMYSKSITESEKVILFNHYI
                     KNIESKEAPDVIVIGIPGGAMPINQEFTNGFGIIAYEVSQAIMPDVVVFSTLYTNSSLE
                     ILQLLSKSFKYKLGYNIDCYNISNTSLDLRASKYEESLQYIVLNLDIINEKKKMYKELD
                     RPVYNILNKNDAKSMTNFLVNKLVEYAENQII"
     aSDomain        19038..20114
                     /aSDomain="TIGR04066"
                     /aSTool="tigrfam"
                     /description="nat_prod_clost: peptide maturation system
                     protein, TIGR04066 family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_289_0007"
                     /evalue="2.90E-133"
                     /identifier="TIGR04066"
                     /label="ctg1_289"
                     /locus_tag="ctg1_289"
                     /protein_end="364"
                     /protein_start="5"
                     /score="442.3"
                     /tool="antismash"
                     /translation="KTMIYPFDVESAPLIRHSNFIDNHNIVNIISPNGWGLCGKDAGHT
                     DGGQPVGIIIDSDFDKALENCDTVFFTDSSMKIDLHKFVYPKIIKAAQSSKNIICTIKL
                     ENEIIDKVSNICNQNNMFFKYFTNESNSMISPPTEKIYQINTPVVLVFGLSERTNKFEI
                     QLNLRENLDEMGYKVSQIGTRHYCELMGFHSFPKFMYSKSITESEKVILFNHYIKNIES
                     KEAPDVIVIGIPGGAMPINQEFTNGFGIIAYEVSQAIMPDVVVFSTLYTNSSLEILQLL
                     SKSFKYKLGYNIDCYNISNTSLDLRASKYEESLQYIVLNLDIINEKKKMYKELDRPVYN
                     ILNKNDAKSMTNFLVNKLV"
     CDS             20157..20453
                     /locus_tag="ctg1_290"
                     /transl_table=11
                     /translation="VNNFSENIDINIKLNEIFKDRFNIDLFNDELNINIDDNLLGSKFR
                     LAARNLYYLLCDIEKEFDITISEEDIDNIKFNTINNIIKIINKELQQKAVETV"
     aSDomain        20184..20414
                     /aSDomain="TIGR04069"
                     /aSTool="tigrfam"
                     /description="ocin_ACP_rel: peptide maturation system acyl
                     carrier-related protein"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_290_0008"
                     /evalue="7.10E-21"
                     /identifier="TIGR04069"
                     /label="ctg1_290"
                     /locus_tag="ctg1_290"
                     /protein_end="86"
                     /protein_start="9"
                     /score="72.5"
                     /tool="antismash"
                     /translation="INIKLNEIFKDRFNIDLFNDELNINIDDNLLGSKFRLAARNLYYL
                     LCDIEKEFDITISEEDIDNIKFNTINNIIKII"
     CDS             20454..22025
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075:alkaline serine protease, subtilase family
                     (Score: 67.3; E-value: 2.6e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_291"
                     /sec_met_domain="Peptidase_S8 (E-value: 6.6e-11, bitscore:
                     40.2, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVTVGIIDDGIGIGFYDTYDIGRSIEITPDSIVQDVDICKLKNAS
                     HGTICAAIVKKYYPKAILTSIKVLNDKTRKCTSKQLIKAIEWCLDNGIQVVNLSLGTID
                     YRDFEIIKETINRACNKGLIIVAACNNRDIFTVPASLSNVIGVKCEKNSILKEGEYIFN
                     LYPISGIEVISCSQHQLLVSGCDSKITSRCNSYAAPMITAEVCKVMDKSPNITLEQIKQ
                     NLYKNSLNYIDDTIQVNNYKNIDWVSNATLLCIKERKCIFESHYINQINNFKEIEDINV
                     DEFDTLILLNSMINDYKKFEPIIYRFKKKQKSIVVIDDEYQGESYKYLNGAVKLWYPSI
                     VEHFYRASPPQQELDVPLIIIYDYTENEMIKVLETLTVKFRRDGYYAVGACTKSLGVLY
                     GLEYIPFRKDRNFKEIKDKIEVLYKVYDYDIMILGLSINRDDTNIIKEINMCLNPDKVI
                     FIGDNFSNEITTWVEKNGVDQNLIITSKENIEKYSDLGHKMFKYTDIELLYTQILNMLL
                     CENEKT"
     PFAM_domain     20457..21137
                     /aSDomain="Peptidase_S8"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00082.24"
                     /description="Subtilase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_291_0020"
                     /evalue="1.40E-13"
                     /label="ctg1_291"
                     /locus_tag="ctg1_291"
                     /protein_end="228"
                     /protein_start="1"
                     /score="50.8"
                     /tool="antismash"
                     /translation="VTVGIIDDGIGIGFYDTYDIGRSIEITPDSIVQDVDICKLKNASH
                     GTICAAIVKKYYPKAILTSIKVLNDKTRKCTSKQLIKAIEWCLDNGIQVVNLSLGTIDY
                     RDFEIIKETINRACNKGLIIVAACNNRDIFTVPASLSNVIGVKCEKNSILKEGEYIFNL
                     YPISGIEVISCSQHQLLVSGCDSKITSRCNSYAAPMITAEVCKVMDKSPNITLEQIKQN
                     LYKNS"
     CDS             22095..22757
                     /locus_tag="ctg1_292"
                     /transl_table=11
                     /translation="MKKIFIKYTIFTLLATVGMTSTVFATENVNVDNSNKQMQEIINKS
                     KHDSDELIKNWDKLKVTAKPDTSKRMNSLDSEGSLNSVGSAGDILVTPATVFGNGPITG
                     HAGMVDLNPDLTIESMTSGGVRRYTNDWKTRYTKALCATVKNADPEQAVDYASSKIGSS
                     YNYNFLNKWKTDTFYCSQLVWRAYIEQGIDLDKDGGNAVLPTDLVSDKIDINWRTNY"
     PFAM_domain     22518..22673
                     /aSDomain="Peptidase_C92"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05708.14"
                     /description="Permuted papain-like amidase enzyme,
                     YaeF/YiiX, C92 family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_292_0021"
                     /evalue="3.30E-08"
                     /label="ctg1_292"
                     /locus_tag="ctg1_292"
                     /protein_end="193"
                     /protein_start="141"
                     /score="33.9"
                     /tool="antismash"
                     /translation="ATVKNADPEQAVDYASSKIGSSYNYNFLNKWKTDTFYCSQLVWRA
                     YIEQGID"
     CDS             22897..23922
                     /locus_tag="ctg1_293"
                     /transl_table=11
                     /translation="MYKNKKVYFFLLIIIMLSLSLSSEVLNDQGLKKIYIIYSDSIQAD
                     SEIVSLDKNLNTRSNIQIPARDIVTSCNEKGTVLLPTSSDNKLFKIDKSETVKSSETDL
                     GGDYIKYKNNEQLTLYNVSLEYNRINFICSDSQIKSLDIKDSLLLSADFDDKNIYVLGY
                     KFDKNKEGDTFLFIIDKSEFKIKDEIKLMKNMRVYDTSLIDDKLFIGVDRKVDFLLYYD
                     VKRSTLNKIEYKDYLKEGTMDTKKILYSDKYIFYISLDGNILQLNKASLDIVRNIKLNN
                     KVILSACLDKDKLYSLSVDINKNNQIGLVDVFDCDNLDNINNLSVGPIRNTTPRDILIL
                     E"
     CDS             23944..24282
                     /locus_tag="ctg1_294"
                     /transl_table=11
                     /translation="MKKIFLTVLPSLLTYLFIYVDSRFPYSKCILIGIYILFPIMFITQ
                     TVISSKSVKNMLIGLLLLSLSIILPINKWYKMSSMMPAIIVYLLLAGITYFLIRTVNFI
                     KRKSKKQI"
     CDS             24615..25508
                     /locus_tag="ctg1_295"
                     /transl_table=11
                     /translation="MQNLLVEIFYDVDNFCIGFENYCKSHFLTENSDRKFAMIKSKTLS
                     LSEVMTITIYFHLSNYRTFKSYYIEHVSTVLKPYFPKLVSYNRFVELMQQSLVALLLYM
                     MKFRTGKCTGISFIDSTTLNVCHNRRIHSHKVFKGIAERGKSSTGWFYGFKLHLVVNDK
                     GDILSFYLTPGNVDDREIKTIEILAKDLFGKLFGDKGYLSKKISDILYSKGIQLITKIK
                     KNMKNKLMLMEDKILLRKRAIIETINDQLKNICQIEHNRHRSFTNFAVNIVSGLISYSF
                     LPKKPSLKLDKYLTME"
     PFAM_domain     24942..25406
                     /aSDomain="DDE_Tnp_1_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13612.8"
                     /description="Transposase DDE domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_295_0022"
                     /evalue="3.00E-76"
                     /label="ctg1_295"
                     /locus_tag="ctg1_295"
                     /protein_end="264"
                     /protein_start="109"
                     /score="254.8"
                     /tool="antismash"
                     /translation="GKCTGISFIDSTTLNVCHNRRIHSHKVFKGIAERGKSSTGWFYGF
                     KLHLVVNDKGDILSFYLTPGNVDDREIKTIEILAKDLFGKLFGDKGYLSKKISDILYSK
                     GIQLITKIKKNMKNKLMLMEDKILLRKRAIIETINDQLKNICQIEHNRHRS"
     CDS             complement(25837..28500)
                     /gene_functions="other (smcogs) SMCOG1037:heavy metal
                     translocating P-type ATPase (Score: 632.8; E-value:
                     1.3e-191)"
                     /gene_kind="other"
                     /locus_tag="ctg1_296"
                     /transl_table=11
                     /translation="MKKYFSKTVEESLKTFDVTLKGLTSEKANKILDSVGENTLNEKKK
                     KSILSVFLEQFKDLLVIILIAAAIISAMTGNMESTFVILAVITMNAILGTVQYVKAEQS
                     LASLKALSAPNAKVIRNGVKIEIPSKTVVPGDILILEAGDLVVADGRILENFSLKVNES
                     SLTGESESVDKFSDVIDKDEVALGDQKNMVFSSSLVTYGRATVLVTNTGMNTELGKIAT
                     LMEETQEKSTPLQISLDEFSKKLAFGIIGICVIVFGLSMYRGIALLDSLMFAVALAVAA
                     IPEALSSIVTIVLAIGTQSMAKENAIIKKLKAVEGLGCVSVICSDKTGTLTQNKMTVKK
                     IFVDNNLIDSTKIDFKNFDSNFLLTSSILCNDSTSKDGAEIGDPTEVALVNLGHKYSLN
                     ELECRSTYPRLKEIPFDSDRKLMSTLHEIDGKYIMVTKGALDVLLNRVTSIKTSNGVVD
                     FTNNDKININNVNRELSSQGLRVLAFAYRELNENKELTLDDEYDYTFLGLISMIDPPRE
                     ESKAAVSDCIKASVKPIMITGDHKITASAIAKEIGILQDGDLAVEGLELDKMSDDELNS
                     KLKHISVYARVSPEHKIRIVKAWQNKGKIVAMTGDGVNDAPALKQADIGIAMGITGTEV
                     SKDAASMILTDDNFATIVKSVTNGRNIYANIKNSIKFLLSGNTSGILAVLYSSIFALPV
                     PFAAVHLLFINLLTDSLPAIAIGMEKSKKDVLKDKPRDAKESILTKDFIIDICSQGLLI
                     GIFTMVSYHIGLATGSHGLAMTMAFSTLCLARLFHGFNCRGKKSIFALGVFNNKFSWIA
                     FISGVVLVNAVLLIPALQGLFEITPLTSNELMLVHLFAFIPTLIIQTVKVVRDFIERKN
                     EKLQEKDILESKSEAA"
     PFAM_domain     complement(25915..26424)
                     /aSDomain="Cation_ATPase_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00689.23"
                     /description="Cation transporting ATPase, C-terminus"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_296_0026"
                     /evalue="5.00E-40"
                     /label="ctg1_296"
                     /locus_tag="ctg1_296"
                     /protein_end="862"
                     /protein_start="692"
                     /score="137.2"
                     /tool="antismash"
                     /translation="PVPFAAVHLLFINLLTDSLPAIAIGMEKSKKDVLKDKPRDAKESI
                     LTKDFIIDICSQGLLIGIFTMVSYHIGLATGSHGLAMTMAFSTLCLARLFHGFNCRGKK
                     SIFALGVFNNKFSWIAFISGVVLVNAVLLIPALQGLFEITPLTSNELMLVHLFAFIPTL
                     IIQTVKV"
     aSDomain        complement(26404..26766)
                     /aSDomain="TIGR01494"
                     /aSTool="tigrfam"
                     /description="ATPase_P-type: HAD ATPase, P-type, family IC"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_296_0010"
                     /evalue="2.70E-32"
                     /identifier="TIGR01494"
                     /label="ctg1_296"
                     /locus_tag="ctg1_296"
                     /protein_end="699"
                     /protein_start="578"
                     /score="109.8"
                     /tool="antismash"
                     /translation="KHISVYARVSPEHKIRIVKAWQNKGKIVAMTGDGVNDAPALKQAD
                     IGIAMGITGTEVSKDAASMILTDDNFATIVKSVTNGRNIYANIKNSIKFLLSGNTSGIL
                     AVLYSSIFALPVPFAAV"
     PFAM_domain     complement(27151..27396)
                     /aSDomain="Cation_ATPase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13246.8"
                     /description="Cation transport ATPase (P-type)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_296_0025"
                     /evalue="4.70E-19"
                     /label="ctg1_296"
                     /locus_tag="ctg1_296"
                     /protein_end="450"
                     /protein_start="368"
                     /score="68.3"
                     /tool="antismash"
                     /translation="LCNDSTSKDGAEIGDPTEVALVNLGHKYSLNELECRSTYPRLKEI
                     PFDSDRKLMSTLHEIDGKYIMVTKGALDVLLNRVTSI"
     aSDomain        complement(27448..28257)
                     /aSDomain="TIGR01494"
                     /aSTool="tigrfam"
                     /description="ATPase_P-type: HAD ATPase, P-type, family IC"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_296_0009"
                     /evalue="2.90E-43"
                     /identifier="TIGR01494"
                     /label="ctg1_296"
                     /locus_tag="ctg1_296"
                     /protein_end="351"
                     /protein_start="81"
                     /score="145.9"
                     /tool="antismash"
                     /translation="VILAVITMNAILGTVQYVKAEQSLASLKALSAPNAKVIRNGVKIE
                     IPSKTVVPGDILILEAGDLVVADGRILENFSLKVNESSLTGESESVDKFSDVIDKDEVA
                     LGDQKNMVFSSSLVTYGRATVLVTNTGMNTELGKIATLMEETQEKSTPLQISLDEFSKK
                     LAFGIIGICVIVFGLSMYRGIALLDSLMFAVALAVAAIPEALSSIVTIVLAIGTQSMAK
                     ENAIIKKLKAVEGLGCVSVICSDKTGTLTQNKMTVKKIFVDNNLIDST"
     PFAM_domain     complement(27589..28170)
                     /aSDomain="E1-E2_ATPase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00122.22"
                     /description="E1-E2 ATPase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_296_0024"
                     /evalue="1.40E-54"
                     /label="ctg1_296"
                     /locus_tag="ctg1_296"
                     /protein_end="304"
                     /protein_start="110"
                     /score="184.5"
                     /tool="antismash"
                     /translation="LSAPNAKVIRNGVKIEIPSKTVVPGDILILEAGDLVVADGRILEN
                     FSLKVNESSLTGESESVDKFSDVIDKDEVALGDQKNMVFSSSLVTYGRATVLVTNTGMN
                     TELGKIATLMEETQEKSTPLQISLDEFSKKLAFGIIGICVIVFGLSMYRGIALLDSLMF
                     AVALAVAAIPEALSSIVTIVLAIGTQSMAKE"
     PFAM_domain     complement(28288..28488)
                     /aSDomain="Cation_ATPase_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00690.28"
                     /description="Cation transporter/ATPase, N-terminus"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_296_0023"
                     /evalue="1.70E-16"
                     /label="ctg1_296"
                     /locus_tag="ctg1_296"
                     /protein_end="71"
                     /protein_start="4"
                     /score="59.8"
                     /tool="antismash"
                     /translation="FSKTVEESLKTFDVTLKGLTSEKANKILDSVGENTLNEKKKKSIL
                     SVFLEQFKDLLVIILIAAAIIS"
ORIGIN
        1 ttatttttta gtttgtgcta aaacttcctt aaaagtattc atatcatatt ttgagctaat
       61 ataaattcta tcaagtttaa gaatattatc atctctatct gagagtcctc tcttagtagt
      121 aaatgctaac gtataacctg aatttttagc tgcggtaaca ctatcatcat taaaatctcc
      181 gaatggatag gcaatagctt caattttttt tcctgttatt gattccaaag tttcttttga
      241 ttccttcaat tcatttaatt gcttatcata tggaagttga ttaagtttgg gatggctaac
      301 agtatggctt tctatatcta ttccgtaatc agacatttct tttatagcct cttttgataa
      361 ataataggaa ccatctagat ctgatgttat acaaaatatt gttgctacca tatttagatt
      421 tttcaaaatt ggaaaagcat tgtagtaatt atccatatag ccatcatcaa aagtaataac
      481 tatgctcttc tcaggaattg gagaattgtt taataagtag ttttttagtt catctaaagt
      541 taatgttata taaccctgat tttttatgta ctcaagctgc atccgaagat tttctggagt
      601 tattgtaacc tcattttcag ctgtttctct cacggaatgg taatataata cgggaactcc
      661 tctattgtca gtaattaagt ttgagccatt aaaggatctt tcgttttgaa ttgtgttttg
      721 ttctatgttg gaaggatcct tttctaatcc atttttagat tcaacatgat tttcatcaat
      781 acttgtatta tcagaactat gattagaagc tatagaattt ttataagata tattatgtag
      841 tattaggtaa atagaaaaca ttacaaacaa taagctaaat atcaaaatac ttaaggaagt
      901 tttatttttg aaaaatcttt tgtaagaaat gtttcttggt ggtaaagttc cttttaacat
      961 gttgttatta ttcacctcct tgtaattaaa acaaatataa ttttctttta taattatacc
     1021 ctaaacttaa agaaaaacta caagacctaa tataagtcat ttgtgatata tattctaatt
     1081 aaaattctaa atctcagcct taattgagtc cttagattac caggggttta aatgtaaatt
     1141 tattagtgca agatattata taaaaaattt atttttatat agtttgagcg gaataactta
     1201 ttgaaaaaag tagcataata taaaaatagt acaacttact aacattatcc acattcgctt
     1261 gtggataaaa tgttataaag ctgttaacat acataatttt acatgttggt tttgtggata
     1321 taaaatatat tatgtcgcaa aatgcataaa tcagggaggc gctaaaatgg gtattatagc
     1381 taatataaca gggctattaa tagtaagttc aatgttatcc actgcttgtc cacaggaaat
     1441 gtttataact aataaaatgc aaagtgaaag caaaattaaa attgtggata aatctataac
     1501 taaaaatcta aattacttaa aattagacat aaatatgcct caattagtag gtgaaaatga
     1561 tgaaaaaaga ataaatttga taaataatgt aattaatcaa gatattttgc caagagctga
     1621 ggagtctgaa aaaacagcga aagaatactt cggagaaaag ggacaagaaa ccccaagatt
     1681 tccatatgaa atttattcaa gatatacaac ctcagaagat aataatcaaa ttcttagcct
     1741 atataatgac tattatgagt ttcttggtgg agctcatggt atgacaacaa ggacttcata
     1801 tacaatagat aagaagaaag aagcgctgct aactttaaag gaattattca gtgaaggata
     1861 taattattct gacataataa ataaagaaat agaaaatcaa ataaaagaga atccagaaaa
     1921 ttattttgat tcaggtaatg tatttaaggg cattagtgaa aatcaaagtt tttatataag
     1981 agacgataac ctagtaatat actaccagct gtatgatata gcgccatatg tatttggaat
     2041 ccctgaattt aaaattcctc taaaactatt tgataaggat tttgtttatt ataaaaattg
     2101 ggattcggga agtaagaagt agataataat tttaattaga taggtcatta aatcgaaagc
     2161 tgattgacat cttaagatta actttaactt atggacttaa aatagatagt aataaattat
     2221 agaacaaatt taaataaaag acatatatat agaaattaaa tcatagcaat tcataaaaat
     2281 ataccatata ggattatatt atctatcctg tatggtatat tttacttaat actatgattt
     2341 aacttattat tactaatatt ttttaattat tataggcact agtgttttga tttcctctaa
     2401 atccataacc atctgaaatt attctgccta ttccagttac cttaccagtt atgcatcctc
     2461 tgcagtgtgc aggtgtatcg cctgtacata ttttacctgg atataatgca taaagctttc
     2521 tatattcacc ttcagtaacg ttaggcatta caacattagc accgctttga agtgcaacta
     2581 ttcttccgtt tggagttaaa gattccattg cagttgttgc aggaatattt atatcaggaa
     2641 gtattaatct agttaaagcc atgaccttta atgctaaagt aagatttcca ccttgagcat
     2701 cctttaaagg tgtatcttca tttggtataa atggacctat accaatcata tctgcattaa
     2761 tttctttaaa gaaaagtata tcactagcga tagattctaa tgtttgattt ggtagaccaa
     2821 caagaatgcc acttccaact tcatatccta agtctcttaa attctttaaa caattcaatc
     2881 tttcctcgaa actcatgtta ggatccatat cttcataaag tttcttatca gtagtttcaa
     2941 ttcttattaa atatctatca gctccagctt ctttaaatgc tttatattcc tcataagttt
     3001 tttcacctaa gcttaaggtt aaagcgacgt ttaatttctt tatctctttt actatgtttg
     3061 tcattctttc tttagtaaaa taatcatctt ctccaccttg aagcacaagt gttttatagc
     3121 cataactaac agccttttta gcaaagtcta gaatttcttc ttcagttaat ctatatcttt
     3181 caagattttt attgtctctg cgtaaaccac aataaaggca atttcttttg caaatatttg
     3241 tgaattctat gagccctctt aaatgaacat aatctcctaa gtatttttga cgtacttcat
     3301 cagcagcttt aaatagttct tcatttatat catcgttttg tagtaattca agtatttcat
     3361 ctttatttaa gtcatgtgta attttagctt tttcaataat tttattcata gttcctccta
     3421 agttaaaaga aattaatagc taactgatat tagtatacta tagaatctaa caacataaca
     3481 acatagtagt ttgtgtaaaa tatgacattc accataacgg actattatta gggcaatgtt
     3541 ttttttagga atcgattaat ctgcagaaga tagtttttat aggactcata ataataggag
     3601 tcataggatt aaatttaata tctacaatac attaatatca atataaaaga agctttgtta
     3661 gagacatgta gaataggaaa aagaataatc tattctatca tgtctattgt tttacgattt
     3721 ttagaaaata acagcatgat atgtactttg ttctcattgc aaatgaatat ataatttata
     3781 tttttattag ataccttagc aattattttg atatgggata aattaaatat tattttcagg
     3841 ataaactata cacagtttgt ttatagtaag tacaactact atacaaaagt aacttgagta
     3901 taaaaattta gaagataatt ttggaggtag aaaatgagag ttacaaatcc agaagaattg
     3961 acaaaaagaa tggagcaaat aagagaagct caaagagaat ttgcaaagtt ttcccaagaa
     4021 gatgtagatg aaatatttag gcaggcagcc atggcagcga atgatgcgag aattactctt
     4081 gctaaaatgg cagtagaaga gagcggcatg ggaatagtag aggataaggt aataaagaat
     4141 cactttgcag ctgagtacat atataaccaa tacaaagata caaagacttg cggagttata
     4201 gagagagatg aaatgtttgg aataactcat attgctgaac ctataggggt aatagctgca
     4261 attgtgccaa caacaaaccc aacatcaaca gcaatattta aaacattaat tgcattaaag
     4321 acaaggaacg gaataattat aagtccacat cctagggcaa agaattcaac aatagcagcc
     4381 gcaaaaatag ttctagaagc agcagaaaga gctggtgcac caaaaggaat aattggatgg
     4441 atagatgagc catcaataga attatccaga aacgttatgg cagaatctga tattatacta
     4501 gctacaggtg gtcctggaat ggttagagct gcgtattcat caggaaaacc agctattgga
     4561 gttggagcag gaaatactcc agctataatt gatgatacag ctcatataaa aatggttgta
     4621 aactcgattt tgctttctaa gacttttgat aacggggtag tttgtgcatc agaacagagc
     4681 ataatagcta tggaatcagt atatgatgag gttctaaagg aattagatga aagaggagct
     4741 tatatactta gaggtgaaga aattgataag gtcagaagta taatattaga ttcaaaggga
     4801 tctttaaatt cagagattgt tggtcagtca gcttacaaga ttgcaaaaat ggctggagta
     4861 gagatatcag aagctgctaa agtattaata ggtgaagttg aatcacctga attagaagaa
     4921 ccattttcac atgaaaaatt gtcaccaata ttaggtatgt ataaagctaa aacttttgat
     4981 gatgcgctaa gattagcttc cagaatgata gaattaggcg gatttggtca tacatcaata
     5041 ctttatacaa atcaaatgga atcagtagac agaatagaga agttcggagt agccatgaag
     5101 accgctagaa ctttaataaa tatgcctgca cctcagggtg caatcgggga tatatataac
     5161 tttaagttag caccatcatt gactcttggc tgtggatctt gggggggaaa ttcaatatcg
     5221 gaaaatgtag gccctaagca tttaattaat gttaaaagaa ttgctgagag gagagaaaat
     5281 attctttggt tcagagttcc agacaaaatc tactttaaat ttggatgtct tccaattgct
     5341 ttagaagaat taaacgcaat gaagaagaaa agggcattca tagtaacaga tagagtatta
     5401 tttgatttgg gttatacgca taagattaca gatattttaa gtgaaaatca tatagaatac
     5461 aagatatttt cagatgtaga acctgatcca acattaaagg ctgcaaattt aggtgcagat
     5521 gcaatgagag actttaatcc agatgttatt atagctatag gtggaggatc gcctatggat
     5581 gcagctaaaa ttatgtgggt aatgtatgag catccagatg ttagatttga agacttagca
     5641 atgagattta tggatattag aaagagagta tatgagttcc ctccaatggg agaaaaggca
     5701 attttagttg caattccaac atcagcagga actggatcag aagtaactcc atttgcagtt
     5761 ataacagatc aacaaacagg agttaagtat ccacttgcag attatgcatt gactcctaat
     5821 atggctataa tagatgcaga acttatgatg agcatgccta aaggattaac agcagcctct
     5881 ggtatagatg ctttagttca tgcaattgag gcgtatgttt cagtgttagc atctgagtat
     5941 acaaatggat tagctttaga agcaataaga ttaacattta aatatttacc agatgcatat
     6001 aatggaggaa ctacaaatat taaagctaga gaaaagatgg cccatgcgtc ttctgtagca
     6061 gggatggctt ttgccaatgc atttttagga atatgccact caatggctca taagttagga
     6121 gcattccacc atgtacctca tggaattgca aatgcattat taatagatga agcgattagg
     6181 tttaatgcaa cagatgcgcc tagaaagcaa gcggctttcc cacaatataa atacccaaat
     6241 gcaggatgga gatatgctag aatagctgat tatttaaatc taggaggaaa tacagaagaa
     6301 gaaaaggttg aattattaat taaagcaata gatgatttaa aggccaaagt tggaatacca
     6361 aagagcataa aggaatttgg agtttcagaa gaaaagttct atgcttcaat ggatgaaatg
     6421 gttgaacagg cgtttgatga tcaatgcaca ggtgcaaatc caagatatcc tttaatgagt
     6481 gaaattaaag agatgtacat aaaatcatat gattaatata atcactaaaa aagatactat
     6541 ggattaagta acttatatat gtatattagt gtatcctaaa tttctatgat aattatgtta
     6601 gttaaataat ataagtataa tgtatataga aactgggtcc ctacatttct tttaattgag
     6661 agtttgatct atcaggattt ctaaggtaag tttattcatt tagtatataa aagtatatat
     6721 ttaagtaact gcaatgttga ttataatata caattcacat tgcagtttac ttattatgat
     6781 aaataaacca taatgaattt ctataaaagc tataagaatt aacatataaa ttacatgaaa
     6841 cctaatcttc aatatacaac gatgcgaatg atttatatat ttaacgataa aatactatat
     6901 aataacttgg aaatgaataa tttgtacaat atttaaaaat attgtaagat tattatacgg
     6961 aatgaaagcc aagtaaagaa aagtaataca tttttaaaag acgtaaggat tagggagagt
     7021 gctacatttg tattcagtta ttttagtcga agatgattcc acgcagagag gaattttaaa
     7081 aacaatgatt aattccatag atgagtctat aaagatttat gaagctgata gtgaaagcgt
     7141 cgctttagaa ataattaaaa atagtgatat taacatgttt ttcatagata ttggtttaaa
     7201 agaatcttca ggattagatc ttgcaatgga tattagagga attcctaaat atgaatttag
     7261 agagattgtt tttttaacaa cgcatgtgga gtacatgttg caagcattta agcagactca
     7321 ttgctatgat tatatattaa aaccttatag caaagatgat gtacaaagta tgctgaataa
     7381 gcttattggt aaagatatta ataatttaag caatgaaatt ggtgatttaa gtagggaact
     7441 tgttataaga ataagaacag gggtattcat aagagtaaag atacatgata tcttatttat
     7501 agaagttaag ggaagagact gtgaagtaaa tactattagc caagtttata catattcaaa
     7561 cataagctta aaaaaaatat tagggttaat tgattgtgaa catatagttc aaagtcataa
     7621 atcttttgcc gtaaataaaa attacatatt taaagtagaa aggttagact ccagattaag
     7681 tacgatatac tttagtaagc attctaaaac agcattgtta gggtataaat ttaagaataa
     7741 tataatatca gagtttaagc aagtaggtag atattatgtt aagtaatttt attgtaaata
     7801 gtttagatgc tatgaatata atttatttat gggtggtatt aaataaaagg aatagtagct
     7861 ggcataggtt tttatttacg gtaattattt gttcaagctc agtcacgact gtagaatact
     7921 ttaaattgaa ctttgttatt tcatatatat taatgactat aacaattaaa attatatata
     7981 aaagagaatt aaaagatatt gtattgcagt tttttttggt attatttaca gaaatgagtt
     8041 ttcaattggt gatttctaca attgtatata gaattattta tggtgagttt attaaaggaa
     8101 ttatcttgga gttaataaca cttgtgagta tagctatttt ttcaaaacta aattctaaca
     8161 ataagattaa ttttgagaaa ataaataatg atatttccat gtacctgatt ttaacattta
     8221 gtatagatgt tataattttt aaaattattt tgatttatga tgatacacta atctcaaaca
     8281 atttaccaat tacagctttg atagttagta tattagttag ttctcaaata ctaatatata
     8341 attatataat tagggggatg aaagaaaatg aaaaattgaa aatatcaagg gaatataatg
     8401 aagtaattaa tgaaattgtt caagagataa agcaacgaca acacgatttt gttaattata
     8461 agaatacaat acgaggaatc gttgaaattg tagatgagga taagatagga caggcgatta
     8521 ggaattatat taaagatgaa gatatatatg atgataagat aaatgaactt gtatatattg
     8581 ataatgtaat tattaggtct atagtatata gaaatatgtg taaggctaag aagaataata
     8641 tcaattttca atatgaaatt gaaaacaatg ttttagataa tattttaagt tataatgaaa
     8701 tatcaaattt attaaataat ttgttgaata atgcttttga ggaagtaatg aaagatgact
     8761 gcatcaaaaa gaatattgaa attaagatcc taaaagaagg ggaaacacat tatctaatag
     8821 ttaaaaataa tctttcaaac gcgaataatg ttaatataaa tgatatgctt accagaggtt
     8881 attccactaa aaatacaggc acacgaggtt atggacttta taatgtagaa caaataatta
     8941 cgtcacataa agggtgcctg gaagttaaag tggaatcaaa agaaattatt ttaaatattt
     9001 attttaataa ttcttcagga taatctggtt cacctatgta gcctgcacag cttgtgtttg
     9061 atactaaatt aaagaattta attagtaagg ctgaaaaaat gtttagtgat ttttgcatta
     9121 taaacacctc ctttaagatt aattattatc acttgaataa cttctaacaa taaacttaga
     9181 aagatacaat tacatacttg tgtgtctcta agtttaaaaa ataatatgca ccagaaagta
     9241 agagatatta aagaaagtat ttttaatatc tttttatttt ttacgggtct tttttcatta
     9301 cgacaaggag cataaactga agttataatg aatgatatta taaaaaatat aatgtaaaaa
     9361 tatatattta atttaggcga taatatgctg aataataata ttattaagaa atatattata
     9421 ctgcaaatta agcacgaatt aaatgttttg caatgaatac ctcccataaa aattcttgtt
     9481 gagtttagaa taacaaaaat caagaaaaag aaaggtaatt gctttagaga taagaagatt
     9541 gataatatta ttactgactt acttaaatcc cctagaatta cttgtagtga atattgaatt
     9601 tttagaagat ccttttcggt taaagaatta ttatttttac ctaagtattc tgttaaaaac
     9661 gttgctactg aatttatcat tttaacctcg catgtatgta attgaatagt acagtcataa
     9721 tatttgtatt attcaatcat ttatttataa gttcatcgat atgaaccatt gtatatttat
     9781 cagttttaag tgttctaact atttgctgca atggtgagtt ttcatcatag gtcacattta
     9841 gcttattatt agtagtatca aaatttatat attttaattc aacaaatgga tgatagtaaa
     9901 agctatgaag tatataaggg ttataattat tgagtccatc aattatagat gaaggatttg
     9961 aatcatgcac atatcctaaa ggggttggta caaataagtg atagtcatca gatttatata
    10021 tgttgctttg tgatccatca aaagattcat atatatactg aaaataatcc tcaataacct
    10081 ttcgttgaag ttgggttttt tgataatgag gactttcgaa atatgatata ggaatgttta
    10141 aagcacttgc agtatcaatc ccgttttcaa caatgcttcg agtttcagga attgtattat
    10201 ttacatcctt agacatttct tcaccagtac cactttcttc attaccatgt tgatgggtat
    10261 aaccatgaag tcctatttta gcgcctctat taattaaata atctaaaaga ttaacaaagc
    10321 ctacatttac tatattatta ttttttaata aatcattatc aatattatct tcaggagatt
    10381 taaatctagg aatccaacta acatgaaatt ttactccttt agaatataaa agatcagcca
    10441 tacattttat ttttgtttga tttgtgtcag taaaatttga accaccacaa gcaaagtctt
    10501 cccatctcat taaggcaatc ttatcactgt ataatatgta aggttcttct ggagctttga
    10561 cattactatt aattaagcta atactattat ttttaaagtc aaatactgca actaaatcaa
    10621 atagttgttc tatatctgat attgaaatat aataagtgcc attatatttt attaaattac
    10681 cacgaagaga acctgaatta gaatttttat aataacaatc tttagttaac gaaattttat
    10741 tattattgcc gtataataaa atttcgttaa ctgaaacata aagggtatag ctaagtttat
    10801 cacaaataaa actaagtggt atatagtatc gttgggattt aagtagcata ggaacattag
    10861 caatgttagt ttcgcttaaa atatttaagt ttactccatt aatttctgcc acaggtgtat
    10921 ctgagaagtt aatcttagaa ttatatgtgc ttttaaaatt actctttgga aatgaacttg
    10981 agtatatggt tttgtttatt ataattatat tttttctgag gttaattata gcataaatta
    11041 taaatataga tagaaatatt cctaaaaaac aaaaaacata gaattttata gttcttttca
    11101 tatgttctct cactcctttt atttatgtat aagttacttc tataaaggtg ttgttaaaaa
    11161 tacatattgt aaaaattcaa ttgatatata aaaagcataa ccctaatcca ataaatgata
    11221 ttcccagtaa attatatttt cattaaatat atatttagct attaaagctg tccaaatata
    11281 tgtaatagca ttacaaggaa ggagaattgt taactgaata tactttaaaa gtattatgtt
    11341 taatattgag cccattccat aaagacacat cccaagaatt aaataaccat ttattttgtt
    11401 actttttgaa gatgattttt taaaaaatgt ccctcctaaa gctccacaca atgtcatgct
    11461 tattataagt aaaaatttta tactatttat cataactatt aaaagacact cctaaaatta
    11521 ttaaaataac tgctaaaact ttgttaggtg ttatggtttc atttagaaaa agattgccgt
    11581 agaacataga tatcacatat gatatgcaca taataggata tactactaca agcttttctt
    11641 tttcaaagga cttaatcata aagatcgaac caaatccata aaataaaaag cctagaggta
    11701 aaaacttaat attatttatg cctattttcc ataataactg acctgtagca gttaaaaacg
    11761 ctgatattaa tatgaacata ataccaattc taattttcat atgaactcct caatttctaa
    11821 tccgttcttg ttaaccttat acctattctt aaccaaagat agcataggct tatctgacaa
    11881 agaatctgaa taagcaaatg aattgtcgaa atcaatttct aaattatttt catttaaata
    11941 ttgttttatc cgatgaacct tttcaatacc cttgcaattt ttgccatgaa tcttattagt
    12001 acatttccca tccaacatct taagcttagt tcctattata gtatcaatag aactattttt
    12061 taaaaaatag tgtaaataca tttctggaga agctgaaact agtagaatat ggcatccctg
    12121 atccttatga aagtttaatt tgctcataac tttttcatta atttttttta atagtacctt
    12181 atcataaaac tcttctaatt gtttttcatt taaatatttt ataggtgcat atatggattc
    12241 tttaacattt tttatatcta taattttaaa aagacacaat aatattttta gaaaaatcat
    12301 aggggtatag aatatgagtc ttactttttt gctaatagca aaaaacaaca ttaaaaacat
    12361 agaatcccca tttataaggg tatgatcaac atcaaaaatt gcaaaaggaa ttttcattaa
    12421 ttctaatacc tcctatatgc ttaaaatggc aatacaagtg aatccccata ataatataca
    12481 attaaaaagt tgcttatctt ttaatactat ttcagccgga tttccaccta cttctttgga
    12541 atacattaag tagtaatatc ttaaaactcc aaaaatgata aaaatacttg tccatataaa
    12601 gttatcatta tatgaaccta atatacaata gatagaatag gacataatag tacatgtcaa
    12661 tgttatagtt ataaatttat ccagtaaatt ttcagtatat tgagataaat tttgtctatg
    12721 ggagctagca ttttcaccca aaacaattat ttcatttcgc cttttaccaa atcctagaaa
    12781 tagggataaa aataatgtac atagaattat ccatctggaa acttgaactg tcgttgaaat
    12841 tccacctgat agtactctta aaataaatcc tagtgatatt gataatatat caattaagaa
    12901 aatattctta agcttaaaag agtaagctag attatttatt acatataaac atattataat
    12961 aaatataaat ttatcttgaa taattgctaa acttaatgat attaaacata acaggattcc
    13021 tactattgaa gcttgaagta gactgatttt accacttgca ataggtctgt tgcatttaat
    13081 aggatgtttt ttatcgcttt ctctatccac aatatcatta agtatataaa tagcggatga
    13141 tatgcagcaa aaagatataa atgtaataaa atttcttttt aataattcaa gattcattaa
    13201 attgttcgaa aaaattattg gaccaaagac aaataagttc ttaacccatt gcttagggcg
    13261 caataatttt atactatatt taaaattatt cattttttcc tccattactg tttacagtat
    13321 tgttattaaa ggctgtaatt gctaatatta taaaaatcca tgaaaaagga tagctatatc
    13381 tgtcttgagc ttctgtgagt aaacattgaa tggcaagacc acaaaacata atataaaaga
    13441 aatcaatttt ataattcaca ttttttttgt tcttatatag gccaatataa gtaagtatta
    13501 aaattgtaat ataaaatagc tgtgtataaa tttgcatatc attacttagc tttattaaat
    13561 ctctaccttc atttttgccc attatgtcta aataatgttc tttattataa gcttcattaa
    13621 gtcctaattg tgaccaataa acaccaccaa agtctcctat acaccattgt ttagcatatt
    13681 taaaaacaaa aaaacataat aattctattt taggtgttgt aattaatctt tgagttatga
    13741 cttcttttgc cgctttatct aaattagaat aatcttcact atatttatct attaaattaa
    13801 aatcttcttc attccagcct ccgcctgaat aaatatttgt accttttagt actgatgtac
    13861 ttattggctc cataggactc caaagaggat tctctgtaat atttaggcct attaatgtgt
    13921 agcttacaat tacataaggg attataaaca ttaaaataat taataagctt ttaattattt
    13981 ttagtttaat tttttctttg aaatatagaa aaatatacat tgtataagca acaatcatta
    14041 tatacccaag gggcctaaaa agctgcatag cacttaaata taagcctgat attaaaaaaa
    14101 atagaagttt atttttaata tatccattaa ttgctttaaa aaacattaat acacttagta
    14161 acaataatgg tatggccaga ttctctgagc aataaacatt attataagta atcataggtg
    14221 ggtaaattga acttaaaagt agtacccaaa tgctttttgt tttgtcttta aaaatctctt
    14281 ttgatataaa aaataataat attatgttta acatagagaa aataacattt ataaatctta
    14341 tagctactaa tggatttgaa aaaactctta tgattaaaga aaaatatata actgtcatgc
    14401 tcatatgtgg aaatctagca aaatagctat aatctctaaa catataagta gatccatgtg
    14461 caaaatcttc tgcacatata aacattctat taaagtcgct tataggaata ctatcaatgt
    14521 tatagaacca taacaatctt ataacaaatg cgcaaatcaa tattatagta ataattgata
    14581 agtgtttata attatttttt agacaataat atgttattcc gattagcata attgaaataa
    14641 taaaacaaaa aattgaaaat aataaattat tatcatcttt ttttaaatat aaatagataa
    14701 tacttcctat tatgggaggt aaaaatagta ccttaagact taaatttaaa aatttattaa
    14761 acatattttt tatattgtcc ataataaaat aatcctttca tactcttagt tattaatgtt
    14821 taaacattga tttaaaattt ccattgataa attgtacatg gttacaactt tatatgtaac
    14881 cataaatata tacgtgaaaa tagtcagtaa cctttgattt aatgtaatta ccacaaaaca
    14941 ataaaaccaa aggaggttac tgaataagtg gttaattata tcaaattatt cgatataatt
    15001 atagaattta ttaattggga tacattgaaa cattcagaat ttaagttaaa tgctgataat
    15061 aaaatttcgc aactttttac taaagatcac ttaaaatcaa tgatttatat atataacata
    15121 agttatttaa ctactaattt ataatacaga aaagagtaaa tatcaacagt aattgcataa
    15181 attgtaatta ttaatgcata aacagaacaa tattacatat attgaaatat tattctgttt
    15241 atgcataatt gtccacaatt caatgaaaat gtatttatta taattggata acatgataat
    15301 atgcactcat agatacgaat tatccaatac acctttggtt ttagctgctt gtttgatttg
    15361 tgtactaaat ttggtacaca aatcaactaa gtaaataata ttttatggag aagtgttatg
    15421 aatggaaaga aagaggacat gcaaatccta aataatcttc taaaattatt taaaccattt
    15481 aaattgaaaa taattttagt aattatctgc ataacaatgt cagctggttt aagtatatta
    15541 acacctactg ttaatcagcg gttaatggat gagggattaa ttgcaaagaa tttgaagata
    15601 attataacat attcaatttg taatttaatt ctaataatga ttattcaggg gttaggaata
    15661 attgaaacta aatatcgttc ttacatagaa aatttattat catataatct tgaggagcaa
    15721 gcttttacac atactttaaa aatgaaaatg agtttctttt tgagcacaaa ctatgctgag
    15781 ataatgaata atttaaaaat agatattgga aatatatccc aaatagtaga tcaaagtaca
    15841 ttttatattg taacaagtat ttttaggatt atagttggaa ttataggact tattactatt
    15901 gactggagac taagtatttt ggtgctaata gcaaccccat taaggtattt aatcgtgaaa
    15961 taccttgcta aaaaaagaag gaacttattc gaaaggttta taaacagtta tgaggatttc
    16021 tcaggctggt atggggacac cattggtgga ataaaagaaa taaaaatttg gggattagaa
    16081 ttatcaaaaa caggtcagtt tataaaaaaa caaaaagaga taataaagca gaatataaga
    16141 atgtcgtatt tggcaaaggc aaatgaaatt tctgaaacag tatttacaca agcaataaca
    16201 tcattaatat atgttattgg tggctattta attataggca atagtcttac tgttggacgg
    16261 ttatttgcat ttatagcata cagttcctat gttactgggc ctatatttgc gattatgaat
    16321 attggttata gttttgcagg cataatgcca tctgcaaaaa gatattttga attcattaat
    16381 acagaaactg aggatatatg cagaaattat atatcaaaaa aattaaattc aagcgaagtt
    16441 ttaggaaaca ttgaatttaa aaatgttgaa ttttcgtata atgataagga atgtgtatta
    16501 aagaatatta gctttaaaat aaatgctggg gagaaggttg ctataattgg aagtaacggt
    16561 tcaggtaaaa caacggttat aaatctgatt ttaagattct taactcctga ttctggcagc
    16621 atactcttgg atggtaacga tattaattct tttaaattaa aggactatag aaaattaata
    16681 tccgtggtaa gccaagacgt gtatttattt aatagtagca taagggaaaa tattatgctt
    16741 aactccaaga aaacagatat tgagatgaat tcagcagtaa aaaaaagtgg agcatataga
    16801 tttatcgaag aaatgcctga caaatatgaa agtattgtag ggcaaagagg aggcacatta
    16861 tctggtggtg aaagacaaaa aatagctatg gctagagctt ttataagaga ttctaagata
    16921 ttagtattgg atgaagccac agctaactat gatatggaag ctgaatatca agtaaataat
    16981 ataattaaag agagttataa agataaaaca attattataa taagccataa gccagatata
    17041 ctggcaaagg tagataaaat tatagttatt aacaatggag taatagaaga tatcggaaat
    17101 catatagatt tatataatag aagtgaattt tataggctga tggtaaatat accattagat
    17161 gagattatct aattgctatt aacatccatt tcttagttct cgagaaagat attggatgat
    17221 aatataaata tttaataaat aatttaaact atgagggagg attttaaaat gagaaaatta
    17281 ggaaaaaaga attatgaaat tattgaaaca gtagaggcat atgaggatga ctgttatgcg
    17341 cagcaagatt gttacaaaag ctgtaaagat agggtagctc gtaaatcatt aaatgacaaa
    17401 ttatttaatg aggcacacta cggcgacggc ggttttcatt ggtaatcgca aacacagatt
    17461 tagttaatta ttattaaaaa ttaaaataaa gcgtaggata agaaatttct aacctacgct
    17521 ttattagtag attatatttg aagaagggga tgatgtatat gaatagcaaa ccattaatta
    17581 agctttttag aacaaatgat aagtattata tgtacgatac aaataaaaac actatcctaa
    17641 atattagtaa taaacaatac aattctttag aaaattatat gaaagacgat atcgatcatt
    17701 atatagattc agaggaaata aatgaatttt ataaggaagg ctttctatct tcaaatagag
    17761 taaaagatat agagagtcct tataatgggg ttctgccatc ttatttagat agtaatgtag
    17821 gaatgataat actacaggta actcaacagt gcaattttag atgtgaatat tgtgtttatt
    17881 caggtaacta cttaaataga actcactcaa gtaaaaaaat ggatatttca atggcattta
    17941 aaggtattga ttttctcatt aatcattcaa gaaatcttag taaaattgat gtatcttttt
    18001 atggaggaga acctcttctt gaatttgatt ttattaaaca atgcattgat tatgctgaaa
    18061 aaaaagcgga aggcaaaaag gtaacgtttt atatgaccac aaatggttct ctattaactg
    18121 atgaggttgt agagttttta tataaacatg atgtgatgtt gacaattagt cttgatgggc
    18181 caaaggaaat acatgataag catagaaagt ttgctttcaa taattgtgga acttttgata
    18241 aggttattaa aaatgttatg aatattgaaa agaagtttcc acaatatatc aataatattc
    18301 tttttaatgt agttattgat actcaaaatg atttttcttg tatagataaa tttttcctag
    18361 attatgagag tataaaagat atagatatga tatctggggt aatatctggt aacaatataa
    18421 aatctattat tgaaatgaat gaagattatt atttaaaagt agaatatgaa ttatttagaa
    18481 ttttctatta tttattacgg aaacataata caaagaattg ctctagaata gtaattgaaa
    18541 gatattctca aatattaaaa ctttcggaag aattgatgcc tcaaaaaatg ttatctgaaa
    18601 aagcacatcc tagtggaccg tgtattcctg gtgctcaaag attatttatg aatgtagatg
    18661 gttttttcta tccatgtgag agggttagtg aaacttctga acttatgcag ataggacata
    18721 tagatacagg ttttgatata aaaaaagtaa caagtatttt taatattggt aagctaaatg
    18781 aggatgattg taaaaattgt tgggctataa gactttgcgg tgtgtgcgct ggtgcgttag
    18841 atatggatac tgatgaaaaa gagttttcaa aaaagaaaag agaagaatgt tgtaagaatg
    18901 ttaaagcatc tttagaagaa aaatttaaaa attattgttt tttaaaggaa tttggtcata
    18961 gttttgacaa aaacgaagaa atgacagtat ttaatgacta attagaaatg gggatgataa
    19021 aaatgaaaaa tgagtataaa actatgatat atccatttga tgtggaatct gcaccactaa
    19081 taagacatag taattttatt gataaccata atattgtaaa tattatttct ccaaatggat
    19141 ggggactttg cggtaaggat gcagggcaca ctgatggtgg acaaccggtt ggtataatta
    19201 tagatagtga ttttgataaa gcactagaaa attgcgatac agtttttttt actgattcta
    19261 gtatgaaaat agatttgcat aaatttgtat atcctaaaat tattaaagca gctcaaagtt
    19321 caaaaaatat aatatgtact ataaaacttg aaaatgaaat tattgataaa gtatcaaata
    19381 tttgcaatca aaataatatg ttttttaagt attttacaaa tgaaagtaat agtatgataa
    19441 gccccccaac tgaaaaaatt tatcaaatta acacacctgt agttttggta tttggtttga
    19501 gtgaaagaac aaacaagttt gagatacaac taaatttaag agaaaactta gatgagatgg
    19561 ggtataaagt atcacaaata ggtacacgac attattgtga gttaatggga tttcattcat
    19621 ttcctaaatt tatgtatagt aaatctatta ctgaatcaga aaaggtgatt ttattcaatc
    19681 attatattaa gaatattgaa agtaaagaag caccagatgt aatagtaatc ggtataccag
    19741 gtggggcaat gcctattaat caggaattta caaatggatt tggcataata gcttatgaag
    19801 tgtcacaagc tattatgcca gatgttgttg tatttagtac attatatact aatagttcac
    19861 tagaaatttt acaattatta tctaagtctt tcaaatataa attgggatat aatatagatt
    19921 gctataatat tagcaataca tctttagatc ttagagctag taaatatgaa gagtcattac
    19981 aatatattgt attaaattta gacattataa atgaaaagaa aaagatgtat aaagagttag
    20041 atagacctgt ttataatatt ttaaataaaa atgatgcaaa aagtatgaca aattttttag
    20101 ttaataaatt ggtagaatat gcggaaaatc aaattatata gtttggagga catgttgtga
    20161 ataatttttc agagaatatt gatataaata taaaattgaa tgagatattt aaggatagat
    20221 ttaatataga cctatttaat gatgaactga atataaatat tgatgataat ttattgggaa
    20281 gtaaatttag attagcagca cgaaatcttt attatttgct atgtgacatt gaaaaagaat
    20341 ttgatattac tatttctgaa gaggatattg ataatattaa atttaataca ataaataata
    20401 ttattaaaat tattaataag gaattacaac aaaaagctgt ggaaacagtt taaatggtaa
    20461 ctgttggaat aattgatgat gggattggta ttgggtttta tgatacatat gacattggac
    20521 gtagtataga gattacacct gattctatag tacaagatgt ggatatatgt aaattgaaaa
    20581 atgccagtca tgggaccatt tgcgctgcta tagtaaaaaa atattaccct aaagctatac
    20641 ttaccagcat aaaagtgctt aatgataaga ctcgtaaatg tacaagtaaa caacttataa
    20701 aagctattga atggtgttta gataatggta tccaagttgt taatcttagc cttggtacca
    20761 tagattatag ggattttgaa ataataaaag agacaattaa tagagcttgc aataaaggtc
    20821 taattattgt agctgcatgt aacaatagag atatatttac agtacctgca tctttaagca
    20881 atgttattgg tgtaaaatgt gagaaaaata gtatcttaaa agaaggagaa tatattttta
    20941 atttatatcc tataagtgga attgaagtaa tctcttgcag tcaacatcaa ttgttagtaa
    21001 gtggttgtga ctcaaaaatt acaagtaggt gtaatagcta tgcagcaccg atgattactg
    21061 ctgaagtttg caaagtaatg gacaaatctc ctaatataac tttagagcaa ataaaacaaa
    21121 atttatataa aaactcactc aattatatag atgatacaat acaagtaaat aattataaaa
    21181 atatagattg ggttagtaat gctacattgc tatgtatcaa ggaaagaaaa tgtatttttg
    21241 agtcacatta tataaatcag attaataatt ttaaagaaat tgaggatata aacgttgatg
    21301 aatttgatac attaatttta ttaaatagca tgataaatga ttataagaaa tttgagccca
    21361 ttatttaccg gtttaaaaaa aaacaaaaaa gtattgttgt tatagatgat gaataccaag
    21421 gggaaagtta taaatatctt aatggtgctg ttaaactttg gtatccttca atagtggagc
    21481 atttttatag ggcatctcca ccacagcaag agttggatgt gccattaata ataatttatg
    21541 actatacaga aaatgagatg ataaaagtat tagaaacatt aacggttaaa tttaggaggg
    21601 atggttatta tgcagtagga gcatgtacaa aatcactagg cgttttatat ggattggaat
    21661 atattccttt tcgtaaagat agaaacttta aagaaataaa agataagatt gaagttttgt
    21721 ataaagttta tgattatgac attatgattc taggattaag cattaataga gacgatacta
    21781 atataattaa agaaattaat atgtgtttaa atcctgataa agttattttt attggagata
    21841 atttctcaaa cgaaataacg acatgggtag aaaaaaatgg cgttgatcag aatttaatta
    21901 taacatcaaa agaaaatatt gaaaagtatt ccgatttggg tcataaaatg tttaaatata
    21961 cagatatcga gttattatat acgcaaattt tgaacatgct tctttgtgaa aatgagaaaa
    22021 cttagtaaaa gagagtaatt tcaaattctt atgagtttac ataatgactc aaacaaatta
    22081 tggggggaca atcaatgaaa aagattttta ttaaatatac tatttttaca cttttagcta
    22141 cagttggtat gacatcaacc gtatttgcca cagaaaacgt taatgttgac aattctaata
    22201 agcaaatgca agaaattata aataaaagta aacatgattc agatgaatta attaaaaatt
    22261 gggacaaact aaaagttacg gctaaaccgg acacatcaaa aagaatgaat agcttagact
    22321 ctgaaggatc actaaatagt gttggaagtg ctggtgatat acttgtaact ccagccactg
    22381 tttttggcaa tggtcctatt acaggacatg ctggaatggt tgatttaaat cctgatctta
    22441 caatagaaag tatgacatct ggaggtgttc gtagatatac gaatgattgg aaaactagat
    22501 atactaaagc tttatgtgct acagtgaaaa atgctgatcc tgaacaagcc gtagattatg
    22561 caagtagtaa aatcggaagt agttataatt acaacttttt aaataagtgg aaaacagata
    22621 cattttattg ttcacaatta gtctggagag cttatataga acaaggtatt gatttagata
    22681 aagatggtgg gaatgctgtt ttaccaactg atttggttag tgataaaatt gatataaatt
    22741 ggagaacaaa ttactaatta attcaatata taattttctt gaaataaacc acttaatggt
    22801 ataaattaat tctgtgttaa tatgaatatt ggcataattt aattttaaac tatatgtggt
    22861 ttatttagac ttgaaattaa gagtgggaga taaataatgt ataaaaataa aaaagtatat
    22921 ttctttttat taataattat aatgttaagc ttaagtttaa gttctgaagt attaaatgat
    22981 caaggattaa aaaaaatata tattatatat tctgactcta ttcaagcaga tagcgaaatt
    23041 gtgagtttag ataaaaattt aaatacaaga agcaatattc agatacctgc aagagatata
    23101 gtgacaagct gtaatgaaaa aggtactgta ttattgccaa catcatcgga taacaaatta
    23161 tttaaaattg ataaaagcga aactgttaaa tcatctgaaa ctgatttggg tggggattac
    23221 ataaaatata aaaataatga acaattaact ttatataatg tatctttaga atataataga
    23281 attaatttca tatgctcaga ctcgcagata aagtcacttg atatcaaaga ctcattgttg
    23341 ttatctgctg attttgatga taaaaatatt tacgtattag gttataaatt tgataaaaat
    23401 aaggaaggtg atacctttct atttattata gataaaagtg agtttaaaat taaagatgaa
    23461 attaaactaa tgaaaaatat gcgggtatat gatacttcgc taattgatga caaacttttt
    23521 attggagtag atagaaaggt agatttttta ttatattatg atgtgaaaag atctactcta
    23581 aataagattg aatacaaaga ttatctaaaa gaaggtacaa tggatactaa aaagattctt
    23641 tatagtgata aatatatttt ttacatatca ttagatggta atatactaca attaaataag
    23701 gcgagtttgg atatcgtgag aaacattaaa ttgaataata aagtaatttt aagtgcttgt
    23761 ttagataaag ataaactata ttctctaagt gtagatataa ataaaaataa tcaaattggt
    23821 ttagttgatg tatttgattg tgataatctt gataatataa ataatctttc agtggggcca
    23881 ataagaaata caactccacg agatatttta atattagaat aataattaaa ggagatataa
    23941 taaatgaaaa aaatattttt aactgtatta ccaagtttat taacatattt atttatatat
    24001 gtagactctc gttttccata tagtaaatgt atattaattg gtatttatat tttatttcct
    24061 attatgttta tcactcaaac tgtcatttct tcaaaatcag taaaaaatat gttaattgga
    24121 ttgctattat tatcgctgtc gattatatta cctattaata aatggtataa aatgagcagc
    24181 atgatgccag ccataatagt ttatctacta ttagctggaa taacatattt tttaataaga
    24241 actgtgaatt ttattaaaag aaagagtaaa aaacaaatct aatacaagtt tttaatattc
    24301 aacttataaa aatactatga aattcatatt tatggagcaa ttaatatata tgtgacatat
    24361 tattagaagt tgggcagaaa aaggtaaatc tcatgtttac agcatataca tagattatta
    24421 tgtggttatt atataaatag catcagaaaa tactaagtat actacgactc aaataggggg
    24481 actttcatta ttttgttaga agtttttagt atattaacgt gagttcgata gaaaaattta
    24541 agggataaaa aatcccatca aaatgtttta ttatataagt gcgaccaaat aaataaaaca
    24601 aaggatggga ttttatgcaa aacttattag tagaaatatt ttatgatgta gacaattttt
    24661 gtattggatt tgaaaattac tgtaaaagtc atttcctaac ggaaaatagc gaccgcaaat
    24721 ttgcaatgat taaaagtaaa actttatcat taagcgaagt tatgacaata actatctact
    24781 ttcatttgtc aaattacaga acttttaaat catactatat tgagcatgtg tctactgttc
    24841 tcaaaccgta ttttcctaag cttgtgagct acaataggtt tgttgaatta atgcaacaat
    24901 cattagttgc attactatta tacatgatga aatttagaac tggcaagtgc acaggaattt
    24961 cttttatcga ttctacaact ttgaatgtat gccataatag aagaatacac tctcataagg
    25021 tttttaaagg aattgcagaa cgtggtaaaa gttcaacagg ctggttttat ggttttaagc
    25081 ttcatcttgt tgttaacgat aaaggggata ttctctcttt ttatctaact ccgggaaatg
    25141 tagatgatag agaaattaag actatagaaa tattagcaaa agatttattt ggaaaacttt
    25201 ttggtgacaa aggttattta tctaaaaaga tctccgatat tttgtattcc aaaggtattc
    25261 aacttataac aaagataaag aaaaacatga aaaataaatt aatgttaatg gaggataaaa
    25321 ttcttcttag gaaaagagct atcattgaaa caataaatga ccaactaaaa aatatatgtc
    25381 agatagagca taatcgacat agaagtttta ctaattttgc ggttaatata gtttcaggat
    25441 tgatttcgta tagttttctt cctaagaaac cttctcttaa gttggacaaa tatctaacta
    25501 tggaataatt ggaatatcga gccacaagat tacaaggata cttttttgct ttttttcata
    25561 accatattta cccataaaat attctagctt ttcgaactca cgttatatta aatcttctaa
    25621 tggatttgat gaaagggtga aaggttattt atatgttaag gcttcaagtg aagacttgaa
    25681 tattaataaa gaatatgtcg tagattttag caatgattga aaaacattaa ttaaatataa
    25741 aaagatagca aaggacgatt cctttactat ctttaagtat agtattaaga caggaataca
    25801 aatatatttt ataagctgct ttagatgcaa atagttttaa gcagcttcac tttttgattc
    25861 taaaatatct ttttcttgaa gcttttcatt ctttctttca ataaaatctc taacaacctt
    25921 aacagtttgt attattaaag ttggaatgaa agcaaataag tgaactaaca ttaattcatt
    25981 actagtaagt ggagttattt caaataatcc ttgaagtgct ggtataagta aaactgcatt
    26041 tacaagtaca acacctgata taaatgcaat ccaactgaat ttgttattga aaactccaag
    26101 agcaaagatg gattttttgc ctcggcagtt aaatccgtgg aataatctag ctaaacataa
    26161 agtgctaaat gccatagtca ttgcaagccc atggcttcct gtagctaaac caatatgata
    26221 agaaaccata gtgaatattc caatcagcaa accttgacta caaatatcta ttataaaatc
    26281 tttagttaaa atagattctt tggcatctct aggtttatct tttaaaacat cttttttaga
    26341 tttttccata ccaattgcaa tggcaggtaa actatctgtt aataagttta tgaataataa
    26401 gtgtacggct gcaaatggaa caggaagtgc aaatattgat gaatatagta ctgcaagaat
    26461 tccagaagta ttacctgaaa gtaggaattt tattgaattc tttatattag cataaatatt
    26521 tcgcccatta gtaactgatt taacaatagt agcaaagtta tcgtctgtta aaatcattga
    26581 agcagcatct tttgaaactt cagtacctgt tatacccatt gcaataccaa tatcagcttg
    26641 ctttaatgca ggtgcatcat taacaccatc tccagtcata gctacaattt tacctttgtt
    26701 ttgccatgct ttaactattc ttattttatg ttctggagat actcttgcgt aaacggaaat
    26761 gtgctttaat tttgagttga gttcgtcatc ggacatttta tcaagttcca agccttctac
    26821 agctaagtca ccatcttgta atattccaat ttctttagca atagcagagg ctgtaatctt
    26881 gtgatctcca gtaatcataa tcggcttgac agaagcttta atacaatcac taacagctgc
    26941 tttagattct tctctaggtg gatcaatcat tgaaattaaa cctaagaaag tataatcata
    27001 ttcatcatct aaagtgagtt ctttattttc attaagctct ctataagcaa atgctaaaac
    27061 tcttaatcct tgagatgata attctctatt aacattattt atattgattt tatcattgtt
    27121 ggtgaagtct actactccat ttgaagtctt tattgaagtt actctattaa gtaatacatc
    27181 aagagcacct ttagtgacca ttatatactt tccatcaatt tcgtgaagag tactcataag
    27241 ctttctgtca gaatcaaaag gaatttcttt aagtcttgga taagtgcttc tacattcaag
    27301 ttcatttaag gagtatttat gacccaagtt tactaaggca acttctgttg gatctcctat
    27361 ctcagcacca tcttttgaag tagaatcgtt acatagtata gaactagtta aaaggaaatt
    27421 tgaatcaaaa tttttgaaat ctattttagt actatcaatt aagttgttat caacgaagat
    27481 ctttttaaca gtcatcttat tttgagttaa tgtaccagtt ttatcagaac agataacaga
    27541 tacacaacca agaccttcaa cagcttttag ctttttaatg atagcattct ctttagccat
    27601 tgattgtgtg cctatggcaa gtacaattgt aactattgag ctaagggctt caggaatagc
    27661 agcaacagca agagcaacgg caaacattaa tgaatctaat agagcaatac ctctgtacat
    27721 acttaatcca aatacaataa cacagatacc aattatccca aaggctaact tcttagaaaa
    27781 ctcatccaag gaaatttgaa gcggggtact tttttcttga gtttcttcca taagagtagc
    27841 tattttacca agctcagtat tcataccagt attagttaca agaacagtag cacgtccata
    27901 agtgactagt gaactagaga aaaccatatt tttttgatca cctaaagcaa cttcatcttt
    27961 gtcaataaca tcagagaact tatccacact ctcagattca ccagttaatg agctctcatt
    28021 aactttaaga gagaagtttt ctaaaattct accatcagca acaactaggt ctccagcctc
    28081 tagtatcaaa atatctcctg gaactacagt tttagaaggt atttcaattt taactccatt
    28141 ccgaataacc ttagcattag gcgcagatag cgcttttaga ctagctagag attgttcagc
    28201 tttaacgtat tgaacagtac ctaaaatagc attcatagtt ataacagcta aaattacaaa
    28261 agtactttcc atatttccag tcatagctga aattatagca gcagcaatta atatgattac
    28321 taataagtcc ttaaattgtt ctagaaatac agataaaatg ctttttttct ttttttcatt
    28381 taaggtgttt tcgcctacag agtctaatat tttattagct ttttcgctcg tcagcccctt
    28441 taaagtcaca tcgaaggttt taagagattc ttctactgtt ttagaaaaat attttttcat
//
