LOCUS       NZ_CP014170.1          20532 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP014170.1 Clostridium tyrobutyricum strain KCTC 5387 chromosome,
            complete genome.
ACCESSION   NZ_CP014170
VERSION     NZ_CP014170.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 12:50:31
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 244779
            Orig. end    :: 265311
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..1386
                     /locus_tag="ctg1_221"
                     /transl_table=11
                     /translation="VNLNFGLNLTQEQKLVMTQQMQLSVRLLQMSSFELKEYIEKEVQE
                     NPILDAKDIELNNNNKEETKLDYKEFIKNIEFDNYSHHSYERNEDKEISPFNFISEKKS
                     LKEYLTEQIRYLGEKDYVKAVCNYIIENIDRRGYLILSNEELGKELKISKDLSDYCIKI
                     VQSLDPSGIGARNLNECLKVQLNRKKLSDENIIQIIDNYLELIAENRYDTIAKKLNIDV
                     KCAQKYGDIIKGLDPKPSRGFYTGEEVKYIMPDAYIRKIDGEYFILMNDDLVPRLTINS
                     MYKDIIKGEDSKENDKNALDYVKDKLNRAVFLIKSIQHRKSTIYRVLEKILEIQRDYFD
                     YGDSYLKPMTLKEISESLDMHESTISRAIREKYIYTSRGTVKIKNLFTTGISSSLNGEN
                     ISASIIKMEIKSIVDGEDKKKPLSDQSMCNLINEKGMNISRRTVAKYREELGIKSSKGR
                     KRY"
     protocluster    1..20532
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[254237:255630]"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      9459..10851
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..20532
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..20532
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="1"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     PFAM_domain     19..150
                     /aSDomain="Sigma54_AID"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00309.22"
                     /description="Sigma-54 factor, Activator interacting domain
                     (AID)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_221_0001"
                     /evalue="5.60E-17"
                     /label="ctg1_221"
                     /locus_tag="ctg1_221"
                     /protein_end="50"
                     /protein_start="6"
                     /score="61.4"
                     /tool="antismash"
                     /translation="LNLTQEQKLVMTQQMQLSVRLLQMSSFELKEYIEKEVQENPILD"
     aSDomain        31..1377
                     /aSDomain="TIGR02395"
                     /aSTool="tigrfam"
                     /description="rpoN_sigma: RNA polymerase sigma-54 factor"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_221_0001"
                     /evalue="6.80E-131"
                     /identifier="TIGR02395"
                     /label="ctg1_221"
                     /locus_tag="ctg1_221"
                     /protein_end="459"
                     /protein_start="10"
                     /score="435.2"
                     /tool="antismash"
                     /translation="QEQKLVMTQQMQLSVRLLQMSSFELKEYIEKEVQENPILDAKDIE
                     LNNNNKEETKLDYKEFIKNIEFDNYSHHSYERNEDKEISPFNFISEKKSLKEYLTEQIR
                     YLGEKDYVKAVCNYIIENIDRRGYLILSNEELGKELKISKDLSDYCIKIVQSLDPSGIG
                     ARNLNECLKVQLNRKKLSDENIIQIIDNYLELIAENRYDTIAKKLNIDVKCAQKYGDII
                     KGLDPKPSRGFYTGEEVKYIMPDAYIRKIDGEYFILMNDDLVPRLTINSMYKDIIKGED
                     SKENDKNALDYVKDKLNRAVFLIKSIQHRKSTIYRVLEKILEIQRDYFDYGDSYLKPMT
                     LKEISESLDMHESTISRAIREKYIYTSRGTVKIKNLFTTGISSSLNGENISASIIKMEI
                     KSIVDGEDKKKPLSDQSMCNLINEKGMNISRRTVAKYREELGIKSSKGRK"
     PFAM_domain     289..849
                     /aSDomain="Sigma54_CBD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04963.15"
                     /description="Sigma-54 factor, core binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_221_0002"
                     /evalue="8.50E-50"
                     /label="ctg1_221"
                     /locus_tag="ctg1_221"
                     /protein_end="283"
                     /protein_start="96"
                     /score="169.2"
                     /tool="antismash"
                     /translation="NFISEKKSLKEYLTEQIRYLGEKDYVKAVCNYIIENIDRRGYLIL
                     SNEELGKELKISKDLSDYCIKIVQSLDPSGIGARNLNECLKVQLNRKKLSDENIIQIID
                     NYLELIAENRYDTIAKKLNIDVKCAQKYGDIIKGLDPKPSRGFYTGEEVKYIMPDAYIR
                     KIDGEYFILMNDDLVPRLTINSMY"
     PFAM_domain     904..1380
                     /aSDomain="Sigma54_DBD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04552.15"
                     /description="Sigma-54, DNA binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_221_0003"
                     /evalue="5.70E-56"
                     /label="ctg1_221"
                     /locus_tag="ctg1_221"
                     /protein_end="460"
                     /protein_start="301"
                     /score="188.8"
                     /tool="antismash"
                     /translation="YVKDKLNRAVFLIKSIQHRKSTIYRVLEKILEIQRDYFDYGDSYL
                     KPMTLKEISESLDMHESTISRAIREKYIYTSRGTVKIKNLFTTGISSSLNGENISASII
                     KMEIKSIVDGEDKKKPLSDQSMCNLINEKGMNISRRTVAKYREELGIKSSKGRKR"
     CDS             1518..2549
                     /locus_tag="ctg1_222"
                     /transl_table=11
                     /translation="VEEVLKLQKRIVPELVDLLEKRYNILRTIYYNQPIGRRVLANDLG
                     IGERIVRTEINFLKTQGFIEINTPGMTITKDGEDIIDKLKDSIHELRGLSEIEDFIKER
                     FKLEKAIIVPGNCDLDKTIMSEIGRAAAIYLKSILKNDSTIAITGGSTMKQVVDNMPRV
                     TNIKNVLVVPARGGMGANVETQANTLSARLAKKLDGNYKLLHIPDSLSDNAVSTIIKEK
                     SIQDILQFIYNADILIYGIGRANKMAKRRGLSDEKIHQIEADGGLGEAFGYYFDKKGNI
                     VYATPSIGIKNSEIDKISTVIAVAGGGSKAEAILSTEISTHGGVLITDEGAAKKIVELI
                     NGQ"
     PFAM_domain     1788..2528
                     /aSDomain="Sugar-bind"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04198.15"
                     /description="Putative sugar-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_222_0004"
                     /evalue="3.60E-71"
                     /label="ctg1_222"
                     /locus_tag="ctg1_222"
                     /protein_end="337"
                     /protein_start="90"
                     /score="239.4"
                     /tool="antismash"
                     /translation="LRGLSEIEDFIKERFKLEKAIIVPGNCDLDKTIMSEIGRAAAIYL
                     KSILKNDSTIAITGGSTMKQVVDNMPRVTNIKNVLVVPARGGMGANVETQANTLSARLA
                     KKLDGNYKLLHIPDSLSDNAVSTIIKEKSIQDILQFIYNADILIYGIGRANKMAKRRGL
                     SDEKIHQIEADGGLGEAFGYYFDKKGNIVYATPSIGIKNSEIDKISTVIAVAGGGSKAE
                     AILSTEISTHGGVLITDEGAAKKIV"
     CDS             2595..3599
                     /locus_tag="ctg1_223"
                     /transl_table=11
                     /translation="MTKVAINGFGRIGRLALRRILEVPDLEVVAINDLTDTKMLAHLFK
                     YDSSQGRFNGEIEVKEGAFVVNGKEVKVFAEADPEKLPWGKLGIDVVLECTGFFTKKEK
                     AEAHIRAGAKKVVISAPAGNDLKTIVFNVNNDSLDGTETVISGASCTTNCLAPMAKVLN
                     DKFGIEKGFMTTIHAYTNDQNTLDGPHRKGDLRRARAAAVSIIPNSTGAAKAISQVIPD
                     LTGKLDGNAQRVPVPTGSITELVSVLKKNVTVEEVNAAMKEAANESFGYTEDPIVSADV
                     VGINYGSLFDATLTKIVDVNGSQLVKTASWYDNEMSYTSQLVRTLAYFAKIAK"
     PFAM_domain     2601..2900
                     /aSDomain="Gp_dh_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00044.26"
                     /description="Glyceraldehyde 3-phosphate dehydrogenase, NAD
                     binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_223_0005"
                     /evalue="2.50E-40"
                     /label="ctg1_223"
                     /locus_tag="ctg1_223"
                     /protein_end="102"
                     /protein_start="2"
                     /score="137.0"
                     /tool="antismash"
                     /translation="KVAINGFGRIGRLALRRILEVPDLEVVAINDLTDTKMLAHLFKYD
                     SSQGRFNGEIEVKEGAFVVNGKEVKVFAEADPEKLPWGKLGIDVVLECTGFFTKK"
     aSDomain        2601..3566
                     /aSDomain="TIGR01534"
                     /aSTool="tigrfam"
                     /description="GAPDH-I: glyceraldehyde-3-phosphate
                     dehydrogenase, type I"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_223_0002"
                     /evalue="1.90E-134"
                     /identifier="TIGR01534"
                     /label="ctg1_223"
                     /locus_tag="ctg1_223"
                     /protein_end="324"
                     /protein_start="2"
                     /score="446.0"
                     /tool="antismash"
                     /translation="KVAINGFGRIGRLALRRILEVPDLEVVAINDLTDTKMLAHLFKYD
                     SSQGRFNGEIEVKEGAFVVNGKEVKVFAEADPEKLPWGKLGIDVVLECTGFFTKKEKAE
                     AHIRAGAKKVVISAPAGNDLKTIVFNVNNDSLDGTETVISGASCTTNCLAPMAKVLNDK
                     FGIEKGFMTTIHAYTNDQNTLDGPHRKGDLRRARAAAVSIIPNSTGAAKAISQVIPDLT
                     GKLDGNAQRVPVPTGSITELVSVLKKNVTVEEVNAAMKEAANESFGYTEDPIVSADVVG
                     INYGSLFDATLTKIVDVNGSQLVKTASWYDNEMSYTSQLVR"
     PFAM_domain     3057..3530
                     /aSDomain="Gp_dh_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02800.22"
                     /description="Glyceraldehyde 3-phosphate dehydrogenase,
                     C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_223_0006"
                     /evalue="2.60E-61"
                     /label="ctg1_223"
                     /locus_tag="ctg1_223"
                     /protein_end="312"
                     /protein_start="154"
                     /score="206.0"
                     /tool="antismash"
                     /translation="LAPMAKVLNDKFGIEKGFMTTIHAYTNDQNTLDGPHRKGDLRRAR
                     AAAVSIIPNSTGAAKAISQVIPDLTGKLDGNAQRVPVPTGSITELVSVLKKNVTVEEVN
                     AAMKEAANESFGYTEDPIVSADVVGINYGSLFDATLTKIVDVNGSQLVKTASWY"
     CDS             3746..4942
                     /locus_tag="ctg1_224"
                     /transl_table=11
                     /translation="MAFNKKTIEDIDVKGKKVLVRCDFNVPLQDGKITDENRLVGALPT
                     IKYLLEKGAKVILCSHLGKPKGEPKPELSLAPVAKRLSEMLGKEVVFAADDNVVGENAK
                     AAVAKLKDGEAVLLQNTRYRIEETKNKENFSKELASLADVFVNDAFGTAHRAHCSTVGV
                     TQFIDTAVCGYLIQKELKFLGNAVEDPTRPFIAILGGAKVSDKINVINNLLEKVDTLII
                     GGGMSYTFEKAQGFTIGTSLVEGDKIDYAKEMIQKAKDKGVKLLLPIDNVVGDKFDASA
                     KPVITEDENIKDGYMGLDIGPKTSKLYADAIKNAKTVVWNGPMGVFEFENFAKGTIAVA
                     KAMAESGATTIIGGGDSAAAVNQLGFGDKMTHISTGGGASLEFLEGKELPGIAALNDK"
     PFAM_domain     3767..4906
                     /aSDomain="PGK"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00162.21"
                     /description="Phosphoglycerate kinase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_224_0007"
                     /evalue="1.20E-164"
                     /label="ctg1_224"
                     /locus_tag="ctg1_224"
                     /protein_end="387"
                     /protein_start="7"
                     /score="547.9"
                     /tool="antismash"
                     /translation="IEDIDVKGKKVLVRCDFNVPLQDGKITDENRLVGALPTIKYLLEK
                     GAKVILCSHLGKPKGEPKPELSLAPVAKRLSEMLGKEVVFAADDNVVGENAKAAVAKLK
                     DGEAVLLQNTRYRIEETKNKENFSKELASLADVFVNDAFGTAHRAHCSTVGVTQFIDTA
                     VCGYLIQKELKFLGNAVEDPTRPFIAILGGAKVSDKINVINNLLEKVDTLIIGGGMSYT
                     FEKAQGFTIGTSLVEGDKIDYAKEMIQKAKDKGVKLLLPIDNVVGDKFDASAKPVITED
                     ENIKDGYMGLDIGPKTSKLYADAIKNAKTVVWNGPMGVFEFENFAKGTIAVAKAMAESG
                     ATTIIGGGDSAAAVNQLGFGDKMTHISTGGGASLEFLEGK"
     CDS             5052..5798
                     /locus_tag="ctg1_225"
                     /transl_table=11
                     /translation="MRKAIIAGNWKMNKTVDEAAKLIEELKPLVKDAKADVVVCPPYVC
                     LDTVLKAAKGTNIKVGAQNMHFEESGAYTGEIAPAMLESMGVEYVILGHSERRQYFNET
                     DAAINKKVKKAFEHNLIPIICCGETLEEREADVTEEVLGKQIKLDLAGLEKSQVEKLVV
                     AYEPIWAIGTGKTATDEQANATIAYIRSVIGKLYGKDTAEKTRIQYGGSVKPATIKAQM
                     AQPDIDGGLIGGASLKAEDFSKIVNY"
     aSDomain        5064..5771
                     /aSDomain="TIGR00419"
                     /aSTool="tigrfam"
                     /description="tim: triose-phosphate isomerase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_225_0003"
                     /evalue="8.10E-60"
                     /identifier="TIGR00419"
                     /label="ctg1_225"
                     /locus_tag="ctg1_225"
                     /protein_end="240"
                     /protein_start="4"
                     /score="200.4"
                     /tool="antismash"
                     /translation="IIAGNWKMNKTVDEAAKLIEELKPLVKDAKADVVVCPPYVCLDTV
                     LKAAKGTNIKVGAQNMHFEESGAYTGEIAPAMLESMGVEYVILGHSERRQYFNETDAAI
                     NKKVKKAFEHNLIPIICCGETLEEREADVTEEVLGKQIKLDLAGLEKSQVEKLVVAYEP
                     IWAIGTGKTATDEQANATIAYIRSVIGKLYGKDTAEKTRIQYGGSVKPATIKAQMAQPD
                     IDGGLIGGASLKAE"
     PFAM_domain     5064..5792
                     /aSDomain="TIM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00121.20"
                     /description="Triosephosphate isomerase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_225_0008"
                     /evalue="5.60E-99"
                     /label="ctg1_225"
                     /locus_tag="ctg1_225"
                     /protein_end="247"
                     /protein_start="4"
                     /score="330.6"
                     /tool="antismash"
                     /translation="IIAGNWKMNKTVDEAAKLIEELKPLVKDAKADVVVCPPYVCLDTV
                     LKAAKGTNIKVGAQNMHFEESGAYTGEIAPAMLESMGVEYVILGHSERRQYFNETDAAI
                     NKKVKKAFEHNLIPIICCGETLEEREADVTEEVLGKQIKLDLAGLEKSQVEKLVVAYEP
                     IWAIGTGKTATDEQANATIAYIRSVIGKLYGKDTAEKTRIQYGGSVKPATIKAQMAQPD
                     IDGGLIGGASLKAEDFSKIVN"
     CDS             5824..7356
                     /locus_tag="ctg1_226"
                     /transl_table=11
                     /translation="MNKKPVMLMILDGFGISDKVEGNAVKAASKPNFDKYYKNYPHTEL
                     GASGLSVGLPDGQMGNSEVGHLNIGAGRIVYQALTKITKSIQDGDFFENEALNKAADNA
                     LKNDSAFHLLGLLSPGGVHSHSEHLKGLIKFAKKKGLKKVYVHAFTDGRDVPPSSAKEF
                     IKDMEDYMKEIGLGEIASVSGRYYAMDRDKRWERVELAYNAIVLGKGKNANSAQEAVDN
                     SYKDGKTDEFIIPTVIEKNNAPIATVKNKDSIVFFNFRPDRARQLTRAIIDREFDGFKR
                     ENLDIEFVTMTEYDDTIKNVDVAFKNEHYKNTLGEYVSNLGKNQLRIAETEKYAHVTFF
                     FNGGVEEPNKNEDRALIPSPKVATYDLQPEMSAYKVTDELLKRIDQDKYDMIILNFANP
                     DMVGHTGILEAAKKAIEAVDVCLGKIVGKILEKDGTVFITADHGNSEQEIDYSTGNPMT
                     AHTTNPVPFVYVANNASEMRDGGVLADIAPTMLEAMGLEKPKEMTGRSLIKK"
     aSDomain        5833..7347
                     /aSDomain="TIGR01307"
                     /aSTool="tigrfam"
                     /description="pgm_bpd_ind: phosphoglycerate mutase
                     (2,3-diphosphoglycerate-independent)"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_226_0004"
                     /evalue="1.20E-224"
                     /identifier="TIGR01307"
                     /label="ctg1_226"
                     /locus_tag="ctg1_226"
                     /protein_end="508"
                     /protein_start="3"
                     /score="744.4"
                     /tool="antismash"
                     /translation="KPVMLMILDGFGISDKVEGNAVKAASKPNFDKYYKNYPHTELGAS
                     GLSVGLPDGQMGNSEVGHLNIGAGRIVYQALTKITKSIQDGDFFENEALNKAADNALKN
                     DSAFHLLGLLSPGGVHSHSEHLKGLIKFAKKKGLKKVYVHAFTDGRDVPPSSAKEFIKD
                     MEDYMKEIGLGEIASVSGRYYAMDRDKRWERVELAYNAIVLGKGKNANSAQEAVDNSYK
                     DGKTDEFIIPTVIEKNNAPIATVKNKDSIVFFNFRPDRARQLTRAIIDREFDGFKRENL
                     DIEFVTMTEYDDTIKNVDVAFKNEHYKNTLGEYVSNLGKNQLRIAETEKYAHVTFFFNG
                     GVEEPNKNEDRALIPSPKVATYDLQPEMSAYKVTDELLKRIDQDKYDMIILNFANPDMV
                     GHTGILEAAKKAIEAVDVCLGKIVGKILEKDGTVFITADHGNSEQEIDYSTGNPMTAHT
                     TNPVPFVYVANNASEMRDGGVLADIAPTMLEAMGLEKPKEMTGRSLI"
     PFAM_domain     6067..6711
                     /aSDomain="iPGM_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06415.15"
                     /description="BPG-independent PGAM N-terminus (iPGM_N)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_226_0009"
                     /evalue="2.50E-89"
                     /label="ctg1_226"
                     /locus_tag="ctg1_226"
                     /protein_end="296"
                     /protein_start="81"
                     /score="298.5"
                     /tool="antismash"
                     /translation="ITKSIQDGDFFENEALNKAADNALKNDSAFHLLGLLSPGGVHSHS
                     EHLKGLIKFAKKKGLKKVYVHAFTDGRDVPPSSAKEFIKDMEDYMKEIGLGEIASVSGR
                     YYAMDRDKRWERVELAYNAIVLGKGKNANSAQEAVDNSYKDGKTDEFIIPTVIEKNNAP
                     IATVKNKDSIVFFNFRPDRARQLTRAIIDREFDGFKRENLDIEFVTMTEYDD"
     PFAM_domain     6853..7167
                     /aSDomain="Phosphodiest"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01663.24"
                     /description="Type I phosphodiesterase / nucleotide
                     pyrophosphatase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_226_0010"
                     /evalue="3.20E-06"
                     /label="ctg1_226"
                     /locus_tag="ctg1_226"
                     /protein_end="448"
                     /protein_start="343"
                     /score="27.1"
                     /tool="antismash"
                     /translation="GVEEPNKNEDRALIPSPKVATYDLQPEMSAYKVTDELLKRIDQDK
                     YDMIILNFANPDMVGHTGILEAAKKAIEAVDVCLGKIVGKILEKDGTVFITADHGNSEQ
                     E"
     CDS             7486..8781
                     /locus_tag="ctg1_227"
                     /transl_table=11
                     /translation="MKNYVEIVDVSARQILDSRANPTVEVEVTLEDGTVGRAGVPSGAS
                     TGAFEAVELRDEDKDVYQGKGVTKAVDNVNNIIAEELIGMNIFDQILIDKTMIELDGTD
                     NKAKLGANATLGVSLACARAAAQYLGLSIYQYIGGVNGKVLPVPMMNILNGGKHADNNV
                     DLQEFMIMPAGAPSFSEAIRMSTEVYHTLKSLLKSKGYDTGVGDEGGFAPNLKSNEEAI
                     QIIVEAIEKAGYKPGKDIYIALDPASSEFYEDGKYNLKGEGKVLTPEQMVDFYVDLANK
                     YPIISLEDGMAEEDWDGWKVLTEKLGSKIQLVGDDLFVTNTTRLKKGIDLGVANSILIK
                     LNQIGTLTETLNAIEMAERAGYTAVVSHRSGETEDTTIADLVVGVNAGQIKTGAPARTE
                     RVAKYNQLLRIEEELGEAAEFRGLNAFYNLKK"
     PFAM_domain     7504..7896
                     /aSDomain="Enolase_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03952.18"
                     /description="Enolase, N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_227_0011"
                     /evalue="2.60E-58"
                     /label="ctg1_227"
                     /locus_tag="ctg1_227"
                     /protein_end="137"
                     /protein_start="6"
                     /score="196.0"
                     /tool="antismash"
                     /translation="IVDVSARQILDSRANPTVEVEVTLEDGTVGRAGVPSGASTGAFEA
                     VELRDEDKDVYQGKGVTKAVDNVNNIIAEELIGMNIFDQILIDKTMIELDGTDNKAKLG
                     ANATLGVSLACARAAAQYLGLSIYQYI"
     aSDomain        7504..8769
                     /aSDomain="TIGR01060"
                     /aSTool="tigrfam"
                     /description="eno: phosphopyruvate hydratase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_227_0005"
                     /evalue="2.00E-213"
                     /identifier="TIGR01060"
                     /label="ctg1_227"
                     /locus_tag="ctg1_227"
                     /protein_end="428"
                     /protein_start="6"
                     /score="706.7"
                     /tool="antismash"
                     /translation="IVDVSARQILDSRANPTVEVEVTLEDGTVGRAGVPSGASTGAFEA
                     VELRDEDKDVYQGKGVTKAVDNVNNIIAEELIGMNIFDQILIDKTMIELDGTDNKAKLG
                     ANATLGVSLACARAAAQYLGLSIYQYIGGVNGKVLPVPMMNILNGGKHADNNVDLQEFM
                     IMPAGAPSFSEAIRMSTEVYHTLKSLLKSKGYDTGVGDEGGFAPNLKSNEEAIQIIVEA
                     IEKAGYKPGKDIYIALDPASSEFYEDGKYNLKGEGKVLTPEQMVDFYVDLANKYPIISL
                     EDGMAEEDWDGWKVLTEKLGSKIQLVGDDLFVTNTTRLKKGIDLGVANSILIKLNQIGT
                     LTETLNAIEMAERAGYTAVVSHRSGETEDTTIADLVVGVNAGQIKTGAPARTERVAKYN
                     QLLRIEEELGEAAEFRGLNAFYN"
     PFAM_domain     7912..8766
                     /aSDomain="Enolase_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00113.24"
                     /description="Enolase, C-terminal TIM barrel domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_227_0012"
                     /evalue="5.90E-141"
                     /label="ctg1_227"
                     /locus_tag="ctg1_227"
                     /protein_end="427"
                     /protein_start="142"
                     /score="469.1"
                     /tool="antismash"
                     /translation="KVLPVPMMNILNGGKHADNNVDLQEFMIMPAGAPSFSEAIRMSTE
                     VYHTLKSLLKSKGYDTGVGDEGGFAPNLKSNEEAIQIIVEAIEKAGYKPGKDIYIALDP
                     ASSEFYEDGKYNLKGEGKVLTPEQMVDFYVDLANKYPIISLEDGMAEEDWDGWKVLTEK
                     LGSKIQLVGDDLFVTNTTRLKKGIDLGVANSILIKLNQIGTLTETLNAIEMAERAGYTA
                     VVSHRSGETEDTTIADLVVGVNAGQIKTGAPARTERVAKYNQLLRIEEELGEAAEFRGL
                     NAFY"
     CDS             8960..9487
                     /locus_tag="ctg1_228"
                     /transl_table=11
                     /translation="MCLILGKVNFTMLRITLLDLLLRATPESFLFVVSSYIFSHKKFAV
                     NSIIKSSIIMALSIYLIRLLPIQFGVHIILNMTVYLILLININKIGCKRSIEYAMVLMA
                     MLSTSELLNIAVVNILCEDSFNIIIKNDFHKNLYFAPSLILFIVGISLYYNLFCKHKRG
                     GNFDVIGRTGIK"
     CDS             9459..10124
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_229"
                     /sec_met_domain="AgrB (E-value: 8.3e-40, bitscore: 133.6,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLVEQASNKIAVKIASILNVNDDEKDIICYGAFCTLQTILSFFW
                     IVLFGIIFHVLPQSLLVVCTIAALRKYSGGQHATAPSRCMIITTFISTSFGLVIKNIFV
                     NFNIALIVSIGVLCFIISFCLVFKFAPADTGSKPISDKNMIYRLKKNSILIVCGLVIID
                     TLLMTFYFKYYNTMLLNLAVCIYMGVIWQSFTLTPIGYKTLYGVDLLMKNMYSRQINT"
     PFAM_domain     9480..10046
                     /aSDomain="AgrB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04647.17"
                     /description="Accessory gene regulator B"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_229_0013"
                     /evalue="4.60E-39"
                     /label="ctg1_229"
                     /locus_tag="ctg1_229"
                     /protein_end="196"
                     /protein_start="7"
                     /score="133.8"
                     /tool="antismash"
                     /translation="SNKIAVKIASILNVNDDEKDIICYGAFCTLQTILSFFWIVLFGII
                     FHVLPQSLLVVCTIAALRKYSGGQHATAPSRCMIITTFISTSFGLVIKNIFVNFNIALI
                     VSIGVLCFIISFCLVFKFAPADTGSKPISDKNMIYRLKKNSILIVCGLVIIDTLLMTFY
                     FKYYNTMLLNLAVCIYMGVIWQSFTL"
     CDS             10210..10677
                     /locus_tag="ctg1_230"
                     /transl_table=11
                     /translation="MLKISLLDLLLRTFPESFLFVFAVYLFCHKKFDRNRIIASTVIFS
                     FAVYSIRLLPIQFGIHTILNILVYVTLCIKINKIPFAKSIAYSLILMAMLSASEQLNTV
                     VLNHIFGQNVSTILNDDLFKNIYFMPSMILFFIGIIICYKVLYRKRENNLF"
     CDS             10711..10851
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_231"
                     /sec_met_domain="TIGR04223 (E-value: 5.2e-07, bitscore:
                     27.1, seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKISIKKTVAKLSKKIFIHAAFSTHNSACVLSAYQPKEPECMRHK
                     K"
     aSDomain        10729..10839
                     /aSDomain="TIGR04223"
                     /aSTool="tigrfam"
                     /description="quorum_AgrD: cyclic lactone autoinducer
                     peptide"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_231_0006"
                     /evalue="7.90E-07"
                     /identifier="TIGR04223"
                     /label="ctg1_231"
                     /locus_tag="ctg1_231"
                     /protein_end="43"
                     /protein_start="6"
                     /score="27.1"
                     /tool="antismash"
                     /translation="KTVAKLSKKIFIHAAFSTHNSACVLSAYQPKEPECMR"
     CDS             10922..11515
                     /locus_tag="ctg1_232"
                     /transl_table=11
                     /translation="MRYLEDMKRKKIYNIISIVKLVSLLFCYIIVYNRISTKNIYLNMN
                     NAFPNVFTVQVLICSIILIYIAWSFFSVKILNFRNTRTIEIVENFIFIALYSVLDIMCR
                     SSVSEYKFMFLFIIITATLQLGIKHGMITALVSAVSVLVIDLIYVPVSSSGVNFQFQND
                     LIVAAVYVLTAWPLGHYVEIEDESIRKKILNLKI"
     CDS             11569..12774
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 214.2; E-value: 7.6e-65)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_233"
                     /transl_table=11
                     /translation="LKNKACYNLLIENSRDSIIVHRFGKIIFLNESAAKIIGISQYNSI
                     KDISMDDIIPKDNRELVNGIYNNIYIKKKTNYTFDQEIVDINGNMLLIRNTSTYFTYEG
                     KPTVLTRIHDISSEKQIQKLEKDVQKSIKLLNESRELNKLITEFLSNVSHELKTPLNVI
                     FSAVQVLDMNDDLTSKNYVVKEKKYLQIVKQNCYRLMRLIENLLDVTKLNSGFLKLSLH
                     NSNIVSFVENITQSIVPYLDEKGIQLIFDTDTEEKIVAIDTDKMERIVLNLLSNSIKFT
                     DKGGKIFVNIVDENDHVLIKFKDTGIGIPQDKIKLIFERFGQVNKSLRRPCEGSGIGLY
                     LVKSFVELHGGTIDVKSKLGVGSEFIVNLPAKNVSENHDEIAIDSDSSLNKINMEFSDI
                     YF"
     aSDomain        11578..11934
                     /aSDomain="TIGR00229"
                     /aSTool="tigrfam"
                     /description="sensory_box: PAS domain S-box protein"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_233_0007"
                     /evalue="2.60E-10"
                     /identifier="TIGR00229"
                     /label="ctg1_233"
                     /locus_tag="ctg1_233"
                     /protein_end="122"
                     /protein_start="3"
                     /score="38.5"
                     /tool="antismash"
                     /translation="KACYNLLIENSRDSIIVHRFGKIIFLNESAAKIIGISQYNSIKDI
                     SMDDIIPKDNRELVNGIYNNIYIKKKTNYTFDQEIVDINGNMLLIRNTSTYFTYEGKPT
                     VLTRIHDISSEKQIQ"
     PFAM_domain     12004..12213
                     /aSDomain="HisKA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00512.27"
                     /description="His Kinase A (phospho-acceptor) domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_233_0014"
                     /evalue="4.60E-13"
                     /label="ctg1_233"
                     /locus_tag="ctg1_233"
                     /protein_end="215"
                     /protein_start="145"
                     /score="49.1"
                     /tool="antismash"
                     /translation="TEFLSNVSHELKTPLNVIFSAVQVLDMNDDLTSKNYVVKEKKYLQ
                     IVKQNCYRLMRLIENLLDVTKLNSG"
     PFAM_domain     12352..12684
                     /aSDomain="HATPase_c"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02518.28"
                     /description="Histidine kinase-, DNA gyrase B-, and
                     HSP90-like ATPase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_233_0015"
                     /evalue="3.20E-26"
                     /label="ctg1_233"
                     /locus_tag="ctg1_233"
                     /protein_end="372"
                     /protein_start="261"
                     /score="92.1"
                     /tool="antismash"
                     /translation="DTDKMERIVLNLLSNSIKFTDKGGKIFVNIVDENDHVLIKFKDTG
                     IGIPQDKIKLIFERFGQVNKSLRRPCEGSGIGLYLVKSFVELHGGTIDVKSKLGVGSEF
                     IVNLPAK"
     CDS             12856..13089
                     /locus_tag="ctg1_234"
                     /transl_table=11
                     /translation="VHTFVLVVQVIIAVLLIAVVLVQPGKTNGLSGFISGGAGESFYSK
                     NKSRTSEAMLSRLTVILAIIFAVLCIIQYLIK"
     aSDomain        12859..13080
                     /aSDomain="TIGR00810"
                     /aSTool="tigrfam"
                     /description="secG: preprotein translocase, SecG subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_234_0008"
                     /evalue="5.50E-24"
                     /identifier="TIGR00810"
                     /label="ctg1_234"
                     /locus_tag="ctg1_234"
                     /protein_end="75"
                     /protein_start="1"
                     /score="82.0"
                     /tool="antismash"
                     /translation="HTFVLVVQVIIAVLLIAVVLVQPGKTNGLSGFISGGAGESFYSKN
                     KSRTSEAMLSRLTVILAIIFAVLCIIQYL"
     PFAM_domain     12865..13077
                     /aSDomain="SecG"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03840.16"
                     /description="Preprotein translocase SecG subunit"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_234_0016"
                     /evalue="1.40E-22"
                     /label="ctg1_234"
                     /locus_tag="ctg1_234"
                     /protein_end="74"
                     /protein_start="3"
                     /score="79.8"
                     /tool="antismash"
                     /translation="FVLVVQVIIAVLLIAVVLVQPGKTNGLSGFISGGAGESFYSKNKS
                     RTSEAMLSRLTVILAIIFAVLCIIQY"
     CDS             13290..15425
                     /locus_tag="ctg1_235"
                     /transl_table=11
                     /translation="MNITEAILNFMREKAYKPTDIKELEKIFGIKKDEKKEFKKILRNM
                     EKDGRVVKTRTNKYGVPERMGLVVGKFQGHQKGYGFVIPEEGTDIFIPISGVNGAMNKD
                     KVMVRVLKEENSGKKCEGEIIRILERANKTIIGIYEDSRNFGFVVPEEKRIYQDIFIPK
                     NCKKGAKTGEVVIVEIVQWPDGRRNPEGKVINVLGKKTEKGIDILTIIKKNGLPEEFPA
                     KVESYADNIPNEIPEEEYERREDLRDLTIVTIDGEDAKDLDDAISIEKLPNGNFYLGVH
                     IADVSNYVTDRSPLDKEALKRGTSVYLIDRVIPMLPKKLSNGICSLNPKVDRLTLSCFM
                     EIDDTGKVVDHKIVESIIRTSERMTYTDVTKILKGEDDKVISRYSYLTGTFQLMGKLAD
                     ILYKKRILRGAVDFDFQECSIILDDLGKPVEIKPYERGISNRIIEEFMLVCNETIAEHM
                     FWSNMPFVYRIHEDPDEEKLMYFNEFVHNLGYTIKWGQEVHPKALQEIIEKVKGKKEET
                     VVSTLLLRSMKQARYSSKCIGHFGLAARYYCHFTSPIRRYPDLIIHRIIKELINGKLDE
                     KEVKRLNVKVEYASKQSSEMERVAQDAEREVDDLKKAEYMSKRIGEEYNGIVSSVTNFG
                     MFVELENTIEGLIHLSTMTDDYYIYDDRHLSLVGEKTRNIYKLGDEVRVRVLKVDMAAH
                     EIYFEMIKDEKNIKEQI"
     aSDomain        13293..15395
                     /aSDomain="TIGR02063"
                     /aSTool="tigrfam"
                     /description="RNase_R: ribonuclease R"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_235_0009"
                     /evalue="1.90E-277"
                     /identifier="TIGR02063"
                     /label="ctg1_235"
                     /locus_tag="ctg1_235"
                     /protein_end="702"
                     /protein_start="1"
                     /score="920.2"
                     /tool="antismash"
                     /translation="NITEAILNFMREKAYKPTDIKELEKIFGIKKDEKKEFKKILRNME
                     KDGRVVKTRTNKYGVPERMGLVVGKFQGHQKGYGFVIPEEGTDIFIPISGVNGAMNKDK
                     VMVRVLKEENSGKKCEGEIIRILERANKTIIGIYEDSRNFGFVVPEEKRIYQDIFIPKN
                     CKKGAKTGEVVIVEIVQWPDGRRNPEGKVINVLGKKTEKGIDILTIIKKNGLPEEFPAK
                     VESYADNIPNEIPEEEYERREDLRDLTIVTIDGEDAKDLDDAISIEKLPNGNFYLGVHI
                     ADVSNYVTDRSPLDKEALKRGTSVYLIDRVIPMLPKKLSNGICSLNPKVDRLTLSCFME
                     IDDTGKVVDHKIVESIIRTSERMTYTDVTKILKGEDDKVISRYSYLTGTFQLMGKLADI
                     LYKKRILRGAVDFDFQECSIILDDLGKPVEIKPYERGISNRIIEEFMLVCNETIAEHMF
                     WSNMPFVYRIHEDPDEEKLMYFNEFVHNLGYTIKWGQEVHPKALQEIIEKVKGKKEETV
                     VSTLLLRSMKQARYSSKCIGHFGLAARYYCHFTSPIRRYPDLIIHRIIKELINGKLDEK
                     EVKRLNVKVEYASKQSSEMERVAQDAEREVDDLKKAEYMSKRIGEEYNGIVSSVTNFGM
                     FVELENTIEGLIHLSTMTDDYYIYDDRHLSLVGEKTRNIYKLGDEVRVRVLKVDMAAHE
                     IYFEMIK"
     aSDomain        13455..15392
                     /aSDomain="TIGR00358"
                     /aSTool="tigrfam"
                     /description="3_prime_RNase: VacB and RNase II family 3'-5'
                     exoribonucleases"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_235_0010"
                     /evalue="1.70E-215"
                     /identifier="TIGR00358"
                     /label="ctg1_235"
                     /locus_tag="ctg1_235"
                     /protein_end="701"
                     /protein_start="55"
                     /score="715.2"
                     /tool="antismash"
                     /translation="TNKYGVPERMGLVVGKFQGHQKGYGFVIPEEGTDIFIPISGVNGA
                     MNKDKVMVRVLKEENSGKKCEGEIIRILERANKTIIGIYEDSRNFGFVVPEEKRIYQDI
                     FIPKNCKKGAKTGEVVIVEIVQWPDGRRNPEGKVINVLGKKTEKGIDILTIIKKNGLPE
                     EFPAKVESYADNIPNEIPEEEYERREDLRDLTIVTIDGEDAKDLDDAISIEKLPNGNFY
                     LGVHIADVSNYVTDRSPLDKEALKRGTSVYLIDRVIPMLPKKLSNGICSLNPKVDRLTL
                     SCFMEIDDTGKVVDHKIVESIIRTSERMTYTDVTKILKGEDDKVISRYSYLTGTFQLMG
                     KLADILYKKRILRGAVDFDFQECSIILDDLGKPVEIKPYERGISNRIIEEFMLVCNETI
                     AEHMFWSNMPFVYRIHEDPDEEKLMYFNEFVHNLGYTIKWGQEVHPKALQEIIEKVKGK
                     KEETVVSTLLLRSMKQARYSSKCIGHFGLAARYYCHFTSPIRRYPDLIIHRIIKELING
                     KLDEKEVKRLNVKVEYASKQSSEMERVAQDAEREVDDLKKAEYMSKRIGEEYNGIVSSV
                     TNFGMFVELENTIEGLIHLSTMTDDYYIYDDRHLSLVGEKTRNIYKLGDEVRVRVLKVD
                     MAAHEIYFEMI"
     PFAM_domain     13497..13670
                     /aSDomain="OB_RNB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08206.13"
                     /description="Ribonuclease B OB domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_235_0017"
                     /evalue="1.10E-19"
                     /label="ctg1_235"
                     /locus_tag="ctg1_235"
                     /protein_end="127"
                     /protein_start="69"
                     /score="70.0"
                     /tool="antismash"
                     /translation="GKFQGHQKGYGFVIPEEGTDIFIPISGVNGAMNKDKVMVRVLKEE
                     NSGKKCEGEIIRI"
     PFAM_domain     13728..13952
                     /aSDomain="CSD2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF17876.3"
                     /description="Cold shock domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_235_0018"
                     /evalue="3.00E-29"
                     /label="ctg1_235"
                     /locus_tag="ctg1_235"
                     /protein_end="221"
                     /protein_start="146"
                     /score="101.1"
                     /tool="antismash"
                     /translation="FVVPEEKRIYQDIFIPKNCKKGAKTGEVVIVEIVQWPDGRRNPEG
                     KVINVLGKKTEKGIDILTIIKKNGLPEEFP"
     PFAM_domain     14016..14999
                     /aSDomain="RNB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00773.21"
                     /description="RNB domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_235_0019"
                     /evalue="7.40E-107"
                     /label="ctg1_235"
                     /locus_tag="ctg1_235"
                     /protein_end="570"
                     /protein_start="242"
                     /score="357.5"
                     /tool="antismash"
                     /translation="REDLRDLTIVTIDGEDAKDLDDAISIEKLPNGNFYLGVHIADVSN
                     YVTDRSPLDKEALKRGTSVYLIDRVIPMLPKKLSNGICSLNPKVDRLTLSCFMEIDDTG
                     KVVDHKIVESIIRTSERMTYTDVTKILKGEDDKVISRYSYLTGTFQLMGKLADILYKKR
                     ILRGAVDFDFQECSIILDDLGKPVEIKPYERGISNRIIEEFMLVCNETIAEHMFWSNMP
                     FVYRIHEDPDEEKLMYFNEFVHNLGYTIKWGQEVHPKALQEIIEKVKGKKEETVVSTLL
                     LRSMKQARYSSKCIGHFGLAARYYCHFTSPIRRYPDLIIHRIIKELI"
     PFAM_domain     15144..15386
                     /aSDomain="S1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00575.25"
                     /description="S1 RNA binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_235_0020"
                     /evalue="4.00E-16"
                     /label="ctg1_235"
                     /locus_tag="ctg1_235"
                     /protein_end="699"
                     /protein_start="618"
                     /score="59.2"
                     /tool="antismash"
                     /translation="RIGEEYNGIVSSVTNFGMFVELENTIEGLIHLSTMTDDYYIYDDR
                     HLSLVGEKTRNIYKLGDEVRVRVLKVDMAAHEIYFE"
     CDS             15462..15932
                     /locus_tag="ctg1_236"
                     /transl_table=11
                     /translation="LTKKKTGRSTLAENRKARHDYFIEESMEAGIELVGTEVKSIREGK
                     ANLKDSYADIMNGEIYVKNMHISPYEKGNIFNKDPLRTRKLLLHKSEISKLLGYTAQKG
                     YTLVPMSLYLKHGRVKVNLAVAKGKRDYDKRNSLMEKAAKRDIDRQMKERYR"
     aSDomain        15492..15917
                     /aSDomain="TIGR00086"
                     /aSTool="tigrfam"
                     /description="smpB: SsrA-binding protein"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_236_0011"
                     /evalue="4.60E-57"
                     /identifier="TIGR00086"
                     /label="ctg1_236"
                     /locus_tag="ctg1_236"
                     /protein_end="152"
                     /protein_start="10"
                     /score="190.1"
                     /tool="antismash"
                     /translation="LAENRKARHDYFIEESMEAGIELVGTEVKSIREGKANLKDSYADI
                     MNGEIYVKNMHISPYEKGNIFNKDPLRTRKLLLHKSEISKLLGYTAQKGYTLVPMSLYL
                     KHGRVKVNLAVAKGKRDYDKRNSLMEKAAKRDIDRQMK"
     PFAM_domain     15495..15920
                     /aSDomain="SmpB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01668.20"
                     /description="SmpB protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_236_0021"
                     /evalue="8.80E-63"
                     /label="ctg1_236"
                     /locus_tag="ctg1_236"
                     /protein_end="153"
                     /protein_start="11"
                     /score="210.6"
                     /tool="antismash"
                     /translation="AENRKARHDYFIEESMEAGIELVGTEVKSIREGKANLKDSYADIM
                     NGEIYVKNMHISPYEKGNIFNKDPLRTRKLLLHKSEISKLLGYTAQKGYTLVPMSLYLK
                     HGRVKVNLAVAKGKRDYDKRNSLMEKAAKRDIDRQMKE"
     CDS             complement(16015..16881)
                     /locus_tag="ctg1_237"
                     /transl_table=11
                     /translation="MVKILLIILVIFALYFLLVFFKDYVQRLKDKEVDNKKFFIFGITG
                     FIANFFDTLGIGSFAILTTLLKNLKLTEDRLIPGTLNVACSIPVVVESLIFITIVKVNV
                     FTLVSMIISATIGAILGASFISKLNERKIQIGMGSALLIVAFIMFSGQINLMPSGGNAT
                     ELTGIRLVIGLIGNFIFGALMTVGIGIYAPCMALVFALGMSPRVTFPVMMGSCAFLEIA
                     ASIKFVKEKSYDIRVPIPTMIFGSIGVIIAAYIVKTLPVFILKWVLIVVIVYTSIIMFR
                     SSKHNSK"
     PFAM_domain     complement(16030..16371)
                     /aSDomain="TauE"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01925.21"
                     /description="Sulfite exporter TauE/SafE"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_237_0023"
                     /evalue="4.10E-08"
                     /label="ctg1_237"
                     /locus_tag="ctg1_237"
                     /protein_end="284"
                     /protein_start="170"
                     /score="33.3"
                     /tool="antismash"
                     /translation="VIGLIGNFIFGALMTVGIGIYAPCMALVFALGMSPRVTFPVMMGS
                     CAFLEIAASIKFVKEKSYDIRVPIPTMIFGSIGVIIAAYIVKTLPVFILKWVLIVVIVY
                     TSIIMFRSSK"
     PFAM_domain     complement(16444..16869)
                     /aSDomain="TauE"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01925.21"
                     /description="Sulfite exporter TauE/SafE"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_237_0022"
                     /evalue="6.70E-09"
                     /label="ctg1_237"
                     /locus_tag="ctg1_237"
                     /protein_end="146"
                     /protein_start="4"
                     /score="35.8"
                     /tool="antismash"
                     /translation="LLIILVIFALYFLLVFFKDYVQRLKDKEVDNKKFFIFGITGFIAN
                     FFDTLGIGSFAILTTLLKNLKLTEDRLIPGTLNVACSIPVVVESLIFITIVKVNVFTLV
                     SMIISATIGAILGASFISKLNERKIQIGMGSALLIVAF"
     CDS             complement(16994..17914)
                     /locus_tag="ctg1_238"
                     /transl_table=11
                     /translation="MISSIANPILRCNNNNKNTLKSLYNTTIKVSTISKNPKTINLKYT
                     SAKPIYTSINLNFNKPVIIAHRAASGAAPENSIPAIDEASKIGYWGVELDVCSSSDGVL
                     YLLHDGTLDRTTNSYGPISSKTSKEIDKLVINKGPNISNYPNLKLPRFEDALLECKKYN
                     LIPVFDIKFLSNKTRDLNTMLRIIKKHNYSHKLLIHSFNYKDLEYLRKRDKGLILMPMV
                     NPNKELYGYRYIKSFKSTELDCNIDYLNKNLIHKAHKDGLKVFCWTIDNPEELKRALNL
                     GVDFIYSDKFNPNDINAYYRPKTIR"
     PFAM_domain     complement(17045..17719)
                     /aSDomain="GDPD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03009.19"
                     /description="Glycerophosphoryl diester phosphodiesterase
                     family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_238_0024"
                     /evalue="1.80E-31"
                     /label="ctg1_238"
                     /locus_tag="ctg1_238"
                     /protein_end="290"
                     /protein_start="65"
                     /score="109.9"
                     /tool="antismash"
                     /translation="HRAASGAAPENSIPAIDEASKIGYWGVELDVCSSSDGVLYLLHDG
                     TLDRTTNSYGPISSKTSKEIDKLVINKGPNISNYPNLKLPRFEDALLECKKYNLIPVFD
                     IKFLSNKTRDLNTMLRIIKKHNYSHKLLIHSFNYKDLEYLRKRDKGLILMPMVNPNKEL
                     YGYRYIKSFKSTELDCNIDYLNKNLIHKAHKDGLKVFCWTIDNPEELKRALNLGVDFIY
                     SDK"
     CDS             18270..18758
                     /locus_tag="ctg1_239"
                     /transl_table=11
                     /translation="MKITIRKYIDKDIPCITRIWNNIVEEAKAFPQIEKMSEKEAEIFF
                     ASQSFTAVAVCDNQILGLYILHPNNIGRCSHIANASYAVCANYRGEHIGEKLVRHSMDK
                     ARELNFSILQFNAVVSTNQSAIHLYEKIGFNRIGIIPAGYLLGDGSYTDIILYYIPLI"
     PFAM_domain     18330..18671
                     /aSDomain="Acetyltransf_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00583.27"
                     /description="Acetyltransferase (GNAT) family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_239_0025"
                     /evalue="5.10E-12"
                     /label="ctg1_239"
                     /locus_tag="ctg1_239"
                     /protein_end="134"
                     /protein_start="20"
                     /score="46.2"
                     /tool="antismash"
                     /translation="NNIVEEAKAFPQIEKMSEKEAEIFFASQSFTAVAVCDNQILGLYI
                     LHPNNIGRCSHIANASYAVCANYRGEHIGEKLVRHSMDKARELNFSILQFNAVVSTNQS
                     AIHLYEKIGF"
     CDS             19205..19684
                     /locus_tag="ctg1_240"
                     /transl_table=11
                     /translation="MNKEERAMKGLWDIFKKRIWLDSFKMKDRLKGYNPSEIHCIAYIG
                     EDEDSNVTKLAESFGMTRGAISKLTKKLVKKGLIESYQKPNNNKEVYFELTEQGKTIYD
                     IHEEMHREFKDRDQPFFEQVTEEQLDIILGFAKKYNMHLDTEIKKLGVDMKSDNL"
     PFAM_domain     19304..19477
                     /aSDomain="MarR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01047.24"
                     /description="MarR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_240_0026"
                     /evalue="4.80E-12"
                     /label="ctg1_240"
                     /locus_tag="ctg1_240"
                     /protein_end="91"
                     /protein_start="33"
                     /score="45.7"
                     /tool="antismash"
                     /translation="NPSEIHCIAYIGEDEDSNVTKLAESFGMTRGAISKLTKKLVKKGL
                     IESYQKPNNNKEV"
     PFAM_domain     19954..20274
                     /aSDomain="FMN_red"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03358.17"
                     /description="NADPH-dependent FMN reductase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_241_0027"
                     /evalue="4.80E-23"
                     /label="ctg1_241"
                     /locus_tag="ctg1_241"
                     /protein_end="107"
                     /protein_start="0"
                     /score="81.7"
                     /tool="antismash"
                     /translation="MNIIGIIASQRKEGNTAFIVNKILEGAKEQGAQTSTFSFSDLDIK
                     PCCGCWACHNGDQGCVINDDMQKIYDALEYADAIVLGSPIYMGQMSAQGKIFTDRLFAR
                     FSP"
     CDS             19954..20532
                     /locus_tag="ctg1_241"
                     /transl_table=11
                     /translation="MNIIGIIASQRKEGNTAFIVNKILEGAKEQGAQTSTFSFSDLDIK
                     PCCGCWACHNGDQGCVINDDMQKIYDALEYADAIVLGSPIYMGQMSAQGKIFTDRLFAR
                     FSPRFSPFFKENAVKQKLILSFNQGNPDAGLFKSYIDYTKHMFEVLEFDAEEVPVVTGL
                     RNGPVHEREDLCTSLKNFGSVLVLEGCQK"
ORIGIN
        1 gtgaacttga attttggact caatctaaca caagaacaaa agttggtaat gacacagcag
       61 atgcagcttt ctgtaaggct tctccaaatg tcaagttttg aacttaaaga atatatagaa
      121 aaggaagtac aggaaaatcc tattctagat gcaaaagata ttgaattaaa caacaataat
      181 aaagaagaaa ctaaacttga ttataaggag tttataaaaa atatagagtt tgataattat
      241 agtcatcata gttatgaaag aaatgaagat aaagaaattt ccccttttaa ttttatatct
      301 gagaaaaagt cattgaaaga gtatttaaca gaacaaataa gatatttggg tgaaaaggat
      361 tacgtaaaag ccgtatgtaa ttatattata gagaatatag atagaagagg gtatttgatt
      421 ctgtccaatg aggaacttgg aaaagaactt aaaatttcaa aagacctttc agattattgt
      481 ataaaaattg tacaatcttt agatccaagc ggaataggtg ccagaaattt aaatgaatgt
      541 cttaaagtac aattaaatag aaaaaaatta tcggatgaaa atataataca gattatagat
      601 aactacttgg aacttattgc tgaaaataga tatgatacta tagcaaaaaa attgaatata
      661 gatgtaaaat gtgcccaaaa atatggagat ataatcaaag gattggatcc taagccatca
      721 cgtggttttt atacaggcga agaggtaaaa tatataatgc ctgatgcata tataagaaaa
      781 attgatggag aatattttat tttgatgaat gatgatcttg tacctagatt gaccataaat
      841 tccatgtata aggatataat aaagggtgaa gattcaaaag aaaatgataa aaatgcactg
      901 gactatgtaa aggacaaact aaacagagct gtatttttaa taaagagtat ccaacataga
      961 aaaagtacta tatatagagt actggaaaag atacttgaaa ttcaaagaga ttattttgat
     1021 tatggagaca gttatttaaa acctatgact ttaaaagaaa tatcagaaag tttagacatg
     1081 catgaatcta ctataagcag agcaataaga gagaaatata tatacacaag cagaggaacg
     1141 gtaaaaataa agaatttatt tactactgga atttcttcat ctttaaatgg tgaaaatatt
     1201 tctgcatcga ttattaaaat ggaaattaaa agtatagtag acggggagga caagaaaaaa
     1261 ccattatctg accagtcaat gtgcaattta attaatgaaa agggtatgaa tatttcaaga
     1321 agaactgtag caaaatatag agaggaactt ggaataaagt cgtcaaaagg gagaaaaagg
     1381 tactgatgat atgcctttaa taacaagttt ttaatatttt ttttaaaata ctatttaaaa
     1441 aagcttgtat atgttttata atagtagtgg gacagttagt aaagtactgg gacactaaca
     1501 ggccaggagg tatggatgtg gaagaagtac ttaaattaca aaaaagaata gtacccgaac
     1561 tagttgattt actggaaaaa aggtacaata ttttaagaac tatttactat aaccaaccta
     1621 ttggcagaag agtacttgca aatgatttgg gaattggtga gagaatagtt agaacagaaa
     1681 taaatttttt aaaaactcaa ggctttattg aaataaatac tcctggaatg actataacaa
     1741 aagatggaga ggacattata gataagttga aagattccat acatgagcta aggggcctgt
     1801 ctgaaatcga agattttata aaggaaagat tcaaacttga aaaagctata attgtgcctg
     1861 gaaattgtga tctagataaa accataatga gtgaaatagg aagggcagcc gcaatttatt
     1921 tgaagagtat cttaaaaaat gacagtacta ttgccattac cggaggctct acaatgaaac
     1981 aggtagttga taatatgcca agggtaacta atataaaaaa tgttcttgta gtaccggcaa
     2041 gaggtggtat gggtgccaat gtagagaccc aggcaaatac cttgtcggca agacttgcta
     2101 aaaagttgga tggcaattat aaattacttc atatcccgga tagtttaagt gataacgctg
     2161 ttagtactat tataaaggaa aagtccatac aggatatatt gcagtttatt tacaatgcag
     2221 atatactgat atatggtata ggcagggcca acaagatggc taaaagaaga ggcctgagtg
     2281 atgaaaaaat acaccagata gaagccgacg gaggtcttgg agaggccttt ggatactatt
     2341 ttgataaaaa gggaaatata gtttatgcaa ccccaagcat aggaataaaa aacagtgaaa
     2401 tagacaaaat aagtacagta atagcagttg cagggggagg cagtaaggca gaagccatac
     2461 tttccacaga aataagtaca catggtggtg tattgattac agacgaaggt gctgcaaaaa
     2521 aaatcgtaga acttataaat ggtcaataaa ttttttattt attataaata tttaattatt
     2581 taggaggagt ttaaatgaca aaggtagcta ttaatggttt tggaagaata ggaagattgg
     2641 cattaagaag aattcttgaa gtaccagact tagaggtcgt tgcaatcaat gatttaactg
     2701 atacaaagat gttagctcat ttattcaaat atgattcatc acagggaaga ttcaatggtg
     2761 aaatagaagt taaagaagga gctttcgtag ttaacggaaa agaagttaaa gtttttgctg
     2821 aagcagatcc tgaaaaatta ccatggggaa aacttggaat agacgttgtt cttgaatgca
     2881 caggtttctt cactaagaag gaaaaagctg aagctcatat aagagccggc gctaagaaag
     2941 ttgttatatc agctcctgct ggaaatgact tgaagacaat agttttcaat gtaaacaatg
     3001 attctttaga tggaactgaa acagttatat caggtgcatc atgtacaact aactgcttag
     3061 ctccaatggc taaagtatta aatgacaagt tcggaataga aaaaggattc atgactacaa
     3121 tccatgcata cactaatgac cagaatacat tagacggacc acacagaaaa ggtgatttaa
     3181 gaagagctag agctgctgct gtcagcataa tacctaactc aactggtgct gctaaagcta
     3241 tcagccaggt tattccagac ttaacaggaa aattagacgg aaatgctcag agggttccag
     3301 ttccaactgg ttcaataact gaattagttt cagttcttaa gaagaatgtt acagttgaag
     3361 aagttaatgc agctatgaag gaagcagcta atgaatcatt cggatatact gaagatccaa
     3421 tagtttctgc agatgttgta ggaatcaact atggttcatt atttgatgca actttaacta
     3481 aaatagtaga tgttaacgga tcacaattag ttaagactgc ttcatggtat gataatgaaa
     3541 tgtcatacac ttcacaatta gttagaactt tagcttactt tgcaaaaatt gctaaatagt
     3601 taaaatttac agctgattat ttaatatgta tatattaaac tggtagcata gtaaaggtct
     3661 ggttttgtag ttgaggctat gaggccgggc ctttaataat taataccaaa ataaataaaa
     3721 aatttaagaa gagaggtata ttattatggc ttttaataaa aagacaattg aagatataga
     3781 tgtcaaggga aaaaaggttt tagttagatg cgatttcaat gttccacttc aggacggaaa
     3841 gataacagat gaaaacaggt tggttggagc acttcctaca ataaaatatt tattggagaa
     3901 aggtgcaaag gttatattgt gttcacacct tggaaagcca aagggagaac caaagccaga
     3961 gctttctttg gcaccagttg caaagagact ttcagaaatg cttggaaaag aagtagtgtt
     4021 tgcagcagat gacaatgtag taggagaaaa tgcaaaagct gcagttgcaa agttaaagga
     4081 cggagaagca gtattacttc aaaatacaag atatagaata gaagaaacaa agaataaaga
     4141 aaacttttca aaagagcttg catcccttgc agatgtattt gtaaatgatg catttggtac
     4201 agctcacagg gcacactgct caactgttgg agttactcag ttcatagata cagctgtatg
     4261 tggatacctg atccagaaag aacttaaatt ccttggaaat gcagtagaag atccaacaag
     4321 acctttcata gctattcttg gaggggcaaa agtttcagac aagataaatg ttataaacaa
     4381 tttacttgaa aaagtagata cacttataat cggaggcgga atgtcctata cctttgaaaa
     4441 agcacaagga tttactatag gaacttcatt agttgaagga gataaaatag actatgcaaa
     4501 agaaatgata caaaaggcaa aggacaaggg agtaaaatta cttctgccta tagataatgt
     4561 tgtaggagac aaatttgatg catcagcaaa acctgttata acagaagatg aaaacataaa
     4621 agatggatat atgggacttg atattggacc taaaacttct aaattatatg cagatgctat
     4681 aaagaatgca aagactgttg tatggaacgg acctatggga gtatttgaat tcgaaaactt
     4741 tgccaaagga actattgcag tagctaaggc tatggcagaa tcaggtgcca ctacaataat
     4801 aggcggcgga gacagtgcag ctgcagttaa ccaattggga tttggtgata agatgactca
     4861 catatctaca ggtggtggag cttcacttga attcctagaa ggaaaagaac ttccaggaat
     4921 agcagcactt aatgataaat aacaaagaac aaagaacaaa taatgaggat tttcggatac
     4981 agccgaaaat cttccgaatt tgatatttgt tctctgaact ttgaacttta aaaaaagaga
     5041 gggagatata aatgagaaaa gcaataattg caggaaactg gaaaatgaat aaaactgttg
     5101 atgaggcagc aaaattaatt gaagaattaa aaccattggt aaaggatgcc aaggcagatg
     5161 tagttgtatg tccaccttat gtatgccttg acacggttct taaagctgca aagggaacca
     5221 acataaaagt tggagctcaa aacatgcatt ttgaagaaag tggtgcatat acaggagaaa
     5281 ttgcaccagc tatgctggaa tcaatgggtg tagaatatgt aatacttgga cacagtgaaa
     5341 gaagacagta tttcaacgaa acagatgctg ctataaataa aaaggtaaag aaagcttttg
     5401 aacacaattt aattcctata atctgctgtg gagagacttt agaagaaaga gaagcagatg
     5461 taactgaaga agtacttgga aaacagatta aattggattt ggcaggactt gaaaaatcac
     5521 aagtagaaaa attagttgta gcttatgaac caatatgggc tataggaaca ggaaaaactg
     5581 ctacagatga acaggcaaat gctacaatag cttatataag aagcgtaatt ggaaaacttt
     5641 atggaaaaga tactgctgaa aagactagaa ttcagtatgg tggatcagtt aagcctgcta
     5701 caataaaagc tcagatggct caaccagata tagatggtgg attaattgga ggagcaagtc
     5761 ttaaagcaga agacttctca aagatagtaa attactaatt tgtaataaaa tttggaggta
     5821 aatatgaata aaaaaccagt aatgcttatg atacttgatg gtttcggtat ttccgataaa
     5881 gtagaaggaa atgcagttaa agcagcaagc aaaccaaatt ttgataaata ctacaaaaat
     5941 tatcctcaca ctgaattagg tgcaagtgga ttaagtgtag gattacctga tggacagatg
     6001 ggaaattcag aagttgggca tttaaatata ggtgcaggaa gaatagtata tcaggctctt
     6061 acaaagataa caaaatcaat acaagatgga gacttttttg aaaatgaagc acttaacaag
     6121 gctgcggaca atgcattgaa aaatgattca gcttttcatt tgcttgggct tttatcacct
     6181 ggaggagttc attctcattc agagcattta aagggactta ttaagtttgc caaaaaaaag
     6241 ggattaaaga aagtatatgt tcatgctttt acagatggca gggatgtacc accatcatct
     6301 gctaaagaat tcataaaaga tatggaagat tacatgaaag aaattggatt aggtgagata
     6361 gcatcggttt caggaagata ctatgctatg gatagagaca aaagatggga aagggtggaa
     6421 cttgcctata atgccatagt acttggaaaa ggtaagaatg ccaatagtgc ccaggaagct
     6481 gtagataatt cctataaaga tggaaagaca gatgagttta taattccaac agtaattgaa
     6541 aaaaacaatg caccaattgc aactgttaaa aataaagact ctatagtttt cttcaatttt
     6601 agaccagaca gggcaagaca acttacaaga gctataatag acagagaatt tgatggattc
     6661 aagagagaaa acctggatat cgaatttgtc accatgacag aatatgacga tacaattaaa
     6721 aatgtagacg tagctttcaa aaatgaacac tacaagaata cattaggaga atatgtaagc
     6781 aatttaggaa aaaatcagct tagaatagct gaaactgaaa aatatgctca tgtcacattc
     6841 tttttcaatg gcggagtgga agaaccaaac aagaatgaag acagagcttt aataccatca
     6901 ccaaaggttg caacttatga ccttcagcca gaaatgagtg cttacaaagt taccgatgaa
     6961 cttttgaaga gaatagatca ggataaatat gacatgatca tattgaattt tgcaaatcca
     7021 gacatggtag gccatacagg aattcttgaa gctgcaaaaa aagcaattga agctgtagat
     7081 gtatgtctcg gcaaaattgt gggtaaaata ctagagaaag atggaactgt gtttataact
     7141 gccgatcatg gtaattcaga gcaggaaata gactactcta caggaaatcc tatgacagca
     7201 catactacaa atcccgttcc ttttgtatat gtggcaaata atgcttcaga gatgagagac
     7261 ggtggagtac ttgcagatat agctccaact atgcttgaag ccatgggact tgaaaaacca
     7321 aaggaaatga ctggcaggag ccttatcaaa aaatagtgta ttttagttat agcttccaat
     7381 attaattgta tgatttgtca tttaaatgat ataattagtt tgaaacaaaa agtataaatt
     7441 agaaaggagt tgaaagaacc gttattttat ttagcggtgg catttatgaa aaattatgta
     7501 gaaattgtag atgtaagtgc aagacaaatt cttgattcaa gagcaaatcc tacagtagag
     7561 gtggaagtta ccttggaaga tggaactgtt ggaagagctg gagtaccatc aggagcatca
     7621 acaggagctt ttgaagctgt tgaactcaga gatgaagaca aagacgtgta tcaaggaaaa
     7681 ggtgttacta aagccgttga caacgtaaat aacatcatag cagaagaatt aataggaatg
     7741 aatatattcg accagatatt aattgacaaa actatgatag agctagatgg tacggacaac
     7801 aaggcaaaat tgggtgccaa tgcaactctt ggagtatcac ttgcttgcgc aagagcagca
     7861 gctcaatatc ttggactcag catatatcaa tatataggcg gagttaatgg caaggttctt
     7921 ccagttccta tgatgaacat attaaatgga ggaaagcatg ctgacaacaa tgtagattta
     7981 caggaattta tgataatgcc ggctggagct cctagtttta gtgaagctat aagaatgagt
     8041 actgaagttt atcatacatt aaagtcactt ttaaaatcaa aaggttatga tacgggtgtt
     8101 ggtgatgagg gaggatttgc tccaaactta aagtccaacg aagaagctat acagataatt
     8161 gtagaagcta tagaaaaagc aggatacaaa cctggaaaag atatatatat agcacttgat
     8221 ccagcttcat ctgaattcta tgaagatgga aaatacaatc taaagggaga aggaaaagtt
     8281 ttaactcctg aacagatggt agatttttat gtggatttgg caaacaaata tcctataatt
     8341 tctcttgagg atggaatggc cgaagaagat tgggatggat ggaaagtcct gactgaaaaa
     8401 cttggaagca agattcagct tgtaggtgac gatctcttcg taacaaatac tacaaggctt
     8461 aaaaagggaa ttgatcttgg agtagcaaat tccatactta taaaattaaa tcagatagga
     8521 acccttactg aaacattaaa tgctatagaa atggcagaaa gagccggata tactgcagta
     8581 gtttcccata ggtcaggaga aactgaagat actactatag ctgatttggt tgtaggtgta
     8641 aatgcaggtc agataaaaac tggtgcgccg gcaagaacag aaagagttgc taagtacaat
     8701 caacttttga gaatagagga agaacttggt gaagctgctg agttcagagg attgaatgca
     8761 ttctataatt taaaaaaata ggcaatttat tttggaatct ggtagtaagt attatgtacc
     8821 agattctttt ttgttgaaaa acataaaaat ttttggaagg gtacttcctt tttcataata
     8881 aagtggtata attagtatat tataagtaat aatatattaa aaattataat tttatatatt
     8941 tatgtcataa tatataataa tgtgtctgat attgggaaag gtaaatttta ctatgcttag
     9001 aataacttta ttggatttat tgttaagggc tacaccagag tcatttttat ttgttgtttc
     9061 cagttatata ttttctcata aaaaatttgc tgtaaattca ataatcaaga gcagtattat
     9121 tatggctctt agcatatacc ttataagatt gcttccaata cagtttggag ttcatataat
     9181 tttaaatatg acggtttatt tgatattgtt aattaatata aataaaattg ggtgtaaaag
     9241 aagtatagag tatgcaatgg tactaatggc catgctttct acaagtgaat tactgaatat
     9301 agctgttgta aatatattat gtgaagatag ttttaatatt ataattaaaa atgattttca
     9361 taaaaatcta tattttgcgc catcactcat actttttata gttggtattt ctttatatta
     9421 caatttattt tgcaaacaca aaagaggagg taattttgat gtcattggta gaacaggcat
     9481 caaataagat agctgtaaaa atagcttcaa ttttaaatgt gaacgatgat gaaaaggata
     9541 taatatgtta tggagcattt tgtaccttac agacaatatt aagctttttt tggattgttt
     9601 tatttggaat catatttcat gtacttcctc aatctctttt ggtagtatgc acaatagctg
     9661 ctcttagaaa gtattcaggg gggcagcatg caactgcacc atcaagatgt atgataatta
     9721 ctacatttat ttcaacatct tttggacttg tcataaaaaa tatatttgta aattttaata
     9781 ttgcactcat agtatccata ggagttttat gtttcataat ttcattttgt cttgtattta
     9841 agtttgcccc agcagatact ggatccaagc ctatttcaga taaaaatatg atatatagac
     9901 taaagaaaaa ttctatttta attgtatgtg ggctagttat aattgatacc ttacttatga
     9961 cattctattt taaatattat aatactatgt tgttgaattt agcagtatgt atatatatgg
    10021 gagttatatg gcagtcattt acccttacac ctattggata taaaacttta tatggagtag
    10081 atctgctaat gaaaaatatg tatagtagac aaattaatac ataaaaactt atttgctgtc
    10141 tgattattta tttttatgca gaacaatagt acaatgataa tatattctaa taatagggga
    10201 gatagacaca tgcttaaaat atctttatta gatttattat tgagaacatt tccagaatca
    10261 tttttgtttg tatttgctgt atatttgttc tgtcataaaa aatttgatag aaatcgtata
    10321 attgccagta ctgttatttt ttctttcgca gtatattcta taagattgct tccaatacag
    10381 tttggaattc acactatttt aaatatactt gtgtatgtga cactatgtat aaaaataaat
    10441 aagattccat ttgctaaaag tattgcatat tctctgattt taatggctat gctttcagca
    10501 agtgaacaat taaatactgt agtattaaat catatatttg gacaaaatgt aagtacaata
    10561 ttaaatgatg atttgtttaa gaacatatat tttatgccat ctatgatttt attctttata
    10621 ggtataataa tttgttataa agtactttac aggaaaagag aaaataattt attttaatat
    10681 tttaatataa aattttggag atgatatact atgaaaattt caattaaaaa aactgtagcc
    10741 aagttaagca aaaaaatatt tattcatgca gcattttcca cacataattc agcatgtgtt
    10801 ctctcagcat atcaacctaa agagcctgag tgcatgagac ataagaaata acatcatgga
    10861 gtgaagtata ggaagtattc ctatacttct tataaatttt aagatacgga tgtgtaatta
    10921 tatgagatat ttggaggata tgaaacgaaa gaagatatac aatattatat ccattgtaaa
    10981 attggtttcc ctattgttct gttatattat agtttataac agaatttcta caaagaacat
    11041 atatttgaat atgaataatg catttcccaa tgtatttaca gttcaggtgt tgatttgttc
    11101 cataatttta atatatattg catggtcttt tttttctgta aaaatactta atttcagaaa
    11161 tactagaacc atagagatag ttgaaaactt tatttttata gcattgtatt ctgtattgga
    11221 tataatgtgc agatccagtg tatctgaata taaattcatg tttttgttta taattattac
    11281 agccactctt cagcttggaa taaaacatgg aatgattaca gccttggtgt cagcagtatc
    11341 agtactggtc atagacttga tatatgttcc agtttcaagt tctggggtta acttccaatt
    11401 ccaaaatgat ctgattgtag ctgcagtata tgtgcttaca gcctggccat taggccacta
    11461 tgtggagatc gaagatgaga gtataaggaa aaaaatattg aacttgaaaa tttaaatagc
    11521 aaaataaata ttcaggatat taagcgaaaa agaatagaag atatgatatt gaaaaacaag
    11581 gcctgttata atctgttgat agaaaattca agagattcaa ttattgtgca tagatttggg
    11641 aaaattatat ttttaaatga aagtgcagct aaaattatag ggatatctca atataatagt
    11701 attaaggata taagtatgga tgatataata ccaaaggata atagagaatt ggtaaacgga
    11761 atatataata atatatatat taaaaagaag actaattata cctttgatca ggaaatagtg
    11821 gacattaatg gtaatatgct attaataaga aatacctcaa catattttac atatgaaggc
    11881 aagcctactg tacttaccag aatacatgat attagttcgg aaaaacaaat tcaaaagctt
    11941 gaaaaagatg ttcaaaaaag tattaagtta ttaaatgaaa gcagggagtt aaacaagctc
    12001 attacagaat tcctgtcaaa tgtttcccat gaactaaaaa caccccttaa tgttattttc
    12061 tcagctgttc aggtattgga tatgaatgat gatttaactt caaaaaacta tgtagtaaag
    12121 gaaaagaaat atttgcaaat agttaagcaa aattgttaca gacttatgag gcttatagaa
    12181 aatctacttg atgttacaaa actcaactct ggatttttaa aacttagtct acataatagc
    12241 aacattgtaa gctttgtaga gaatataaca caatccatag ttccttattt ggatgaaaag
    12301 ggtatacaat tgatttttga tactgatact gaggaaaaga tagtagctat agatacagac
    12361 aaaatggaaa gaatagtatt gaatcttctt tccaattcaa taaaatttac tgataaaggc
    12421 ggtaagatat ttgtaaatat agtagatgaa aatgatcatg tcctcattaa atttaaagat
    12481 acaggcatag gtattcctca agataagata aaactgatat ttgaaagatt cggccaggtt
    12541 aataaaagcc ttagaaggcc atgtgaagga agcggcatag gcctctatct tgtaaaatca
    12601 tttgtagaat tgcatggagg aactatagat gtgaaaagca aactgggggt cggaagtgaa
    12661 tttatagtaa atttacctgc aaaaaatgta tctgaaaatc atgatgaaat agctattgat
    12721 agtgatagca gtttaaacaa gataaatatg gaattttcag atatatactt ttaaaaattg
    12781 aaattaggct ttatatgtga taaaatgtat gttatgtcaa tagcgttgtt agttgataat
    12841 taggagggcg atttcgtgca tacttttgtt ttggtagtgc aagttataat agcagtactt
    12901 ttaatagctg tagtattggt acagcctgga aagaccaatg ggttaagcgg atttatatca
    12961 ggtggggctg gcgagagttt ttattccaaa aataaatcaa gaacttcaga agccatgctt
    13021 tcaagattga ctgtgatttt agctataatt tttgcagtgt tgtgtataat tcagtattta
    13081 ataaagtagg tataccgtga atacagcaga gtttagattc tgaggtattc atttttttat
    13141 ataattgttt tcttcgggtt tggaattact tttaaaaaat tatatacgag ggttaagttc
    13201 agaagtataa tgtaaatagt ggatatgttt ataaaaatat tgaatatttt tagtgaaatt
    13261 gtaccaacat aataaaaggt ggtgaatata tgaatataac agaagcaatt ttaaatttta
    13321 tgagagaaaa ggcatataag cctacagata taaaggaatt ggaaaaaatt ttcggtataa
    13381 aaaaagatga aaaaaaggaa ttcaagaaga tacttagaaa tatggaaaag gacggacggg
    13441 tagttaagac aaggaccaat aaatacggtg tacctgagag aatgggactt gtagtaggaa
    13501 agtttcaagg gcatcaaaaa ggttatggat tcgtaattcc tgaagaggga accgatatat
    13561 ttatacctat ttccggtgtg aatggtgcca tgaacaaaga caaggtaatg gtaagagttt
    13621 taaaagaaga aaacagcgga aaaaaatgtg aaggagaaat aataaggata cttgaaaggg
    13681 ctaacaagac tattataggt atttatgagg acagcagaaa ttttggattt gtagtgccag
    13741 aagaaaagag aatatatcag gatatattta tacccaagaa ttgcaaaaaa ggggcaaaaa
    13801 ccggggaagt agttattgtg gagatagttc agtggcctga tgggagaaga aatccagaag
    13861 ggaaggtaat aaacgtactt ggaaagaaga ctgaaaaggg aatagacata ttgaccataa
    13921 tcaaaaagaa tggtcttcct gaagagttcc ctgcaaaagt tgaaagctat gcagataata
    13981 taccaaatga aattccagag gaggaatatg aaagaagaga ggatttaagg gatcttacaa
    14041 tagtcacaat agatggtgaa gatgcaaagg acttggatga tgccatatct attgaaaagc
    14101 ttccaaatgg taatttttat ttaggagttc acatagcaga tgtttccaac tatgtaacag
    14161 atagaagccc attggataaa gaagcactta agaggggaac ttctgtatat ttaatagata
    14221 gggtcatacc tatgctccct aaaaaattgt caaatggaat atgcagtttg aaccctaaag
    14281 ttgacagact tactttaagc tgttttatgg aaatagatga tacaggcaag gtagtagacc
    14341 ataaaattgt ggagagcata ataagaacaa gtgaaagaat gacatataca gatgttacca
    14401 agatattaaa aggtgaagac gacaaggtga taagcagata tagttatctg acaggtacat
    14461 tccagcttat gggaaaactt gccgacatat tgtataagaa gagaatactt aggggagctg
    14521 tagactttga ttttcaagaa tgcagtataa tacttgacga tctgggaaaa cctgtagaaa
    14581 taaagcctta tgaaagagga atttcaaatc gcataataga ggaatttatg cttgtatgta
    14641 atgaaactat agctgagcat atgttctgga gcaatatgcc tttcgtatat agaatacatg
    14701 aagaccctga tgaagaaaag ttgatgtact ttaatgagtt tgtacacaac ttggggtaca
    14761 ctataaagtg gggacaggaa gttcatccaa aggcacttca ggaaattata gaaaaggtaa
    14821 agggcaaaaa ggaagagaca gtagtcagta cacttctttt aagatccatg aaacaggcaa
    14881 gatattcttc taaatgtata ggacattttg gcctggcggc aaggtattac tgccatttta
    14941 catctccaat aagaaggtat ccggatttaa tcattcacag gataataaag gaattaataa
    15001 atggtaaact ggatgaaaaa gaagtaaaga gattgaatgt aaaagttgaa tatgcttcaa
    15061 agcaatcttc agaaatggag agggtggcac aggatgctga acgagaagtg gatgacttga
    15121 agaaggctga atacatgagt aagagaatag gagaagaata caatggtata gtatcctctg
    15181 ttaccaattt tggaatgttt gtggagcttg aaaatacaat tgaaggattg attcatctaa
    15241 gtactatgac tgacgattat tatatatatg atgacaggca tttgtcactt gtaggggaga
    15301 agaccaggaa tatctataaa ttgggggatg aagttagggt aagggtgctc aaagttgata
    15361 tggcagctca tgaaatttat tttgagatga ttaaagatga aaaaaatatc aaagagcaaa
    15421 tttaaacttt aatatttgaa ctttgtaaag gggtgatatg gttgactaaa aagaagacag
    15481 ggagaagtac cctggctgaa aatagaaagg caaggcatga ttattttatt gaggaatcaa
    15541 tggaagctgg aattgaactc gtaggaacgg aagtaaagtc cataagagaa ggaaaggcaa
    15601 acctgaagga tagttatgca gatataatga atggtgagat atatgtaaaa aatatgcata
    15661 taagccctta cgaaaaggga aatattttta acaaggatcc tttgaggacg agaaagttac
    15721 tacttcataa atctgaaata tcgaagcttc ttggatatac agcccaaaaa gggtataccc
    15781 tggttccaat gtctctctat cttaagcatg gacgcgtaaa agtaaatttg gcggttgcca
    15841 aaggtaaaag agactatgac aagagaaatt ctcttatgga aaaggcagcc aagagggata
    15901 tagacaggca aatgaaagaa agatatagat aactgaagag ataaatatat attaatcata
    15961 taatatctaa ccttaatata atcttatacc aaggttggat atttttatat agatttattt
    16021 ggagttatgt tttgaagatc tgaacatgat tatcgaggta tatactatga ctactataag
    16081 tacccacttg agtataaaaa caggcaatgt tttaactatg tatgcagcta ttatgacacc
    16141 aatacttcca aatatcatag ttggaatcgg aactcttata tcataagatt tttcttttac
    16201 aaattttatt gaagcggcaa tttctaaaaa tgcacatgat cccatcataa cgggaaatgt
    16261 tactcttggg ctcatgccaa gggcaaatac caatgccatg cagggagcat aaattcctat
    16321 gccaacagtc ataagagctc caaatatgaa atttcctatt aaacctataa ccagacgtat
    16381 tccagttaat tcagtagcat ttcctccaga gggcattaaa tttatctgtc ctgaaaacat
    16441 tataaatgcc actattagga gggctgaacc cattcctatc tgaattttcc tttcatttaa
    16501 ttttgatata aatgaagctc ctaaaatagc gccaattgta gctgatataa tcatggacac
    16561 taaagtaaat acgtttactt taactatagt tataaatata agggattcaa ctactacagg
    16621 tatggaacaa gctacattta gtgtacctgg tatgagtctg tcttcagtaa gtttgaggtt
    16681 ttttaaaagt gtagttaaaa ttgcaaaact ccctattcca agagtatcaa aaaaatttgc
    16741 tataaaacct gttattccaa atataaaaaa ttttttattg tctacttctt tatcctttaa
    16801 tctttgtaca tagtctttga aaaatacaag taaaaagtat agtgcaaaga taacgagtat
    16861 aattaataaa attttgacca ttgctcacat tccctccgat gtaataaaac caaatagata
    16921 tattcgacaa taattttaaa aatccttcat aaatagaaaa ctccaacctg attttaaagc
    16981 tggaattttt tacttatctt attgttttag gcctataata tgcatttatg tcattgggat
    17041 taaatttatc agagtatatg aaatctacac ctagatttaa tgccctttta agttcttcag
    17101 gattgtcaat tgtccagcag aatactttta gcccatcttt atgggcttta tgtataagat
    17161 tcttgtttag atagtcaata ttacaatcta gttcagtaga tttaaatgat tttatatatc
    17221 tatagccata aagttcttta tttgggttta ccataggcat caagataagt cctttgtctc
    17281 ttttacgaag atactctaaa tccttatagt taaatgaatg aattaataat ttatggctgt
    17341 agttatgctt ttttataatt cttaacattg tatttaaatc tctagttttg ttgctaagaa
    17401 attttatatc aaataccggt ataagattgt attttttaca ttctaaaaga gcatcttcaa
    17461 atctaggcaa tttcaagttt gggtaattgg atatattcgg gcctttattg atcacaagct
    17521 tgtctatttc cttggaagtt tttgacgata ttgggccata actattagtg gtcctatcaa
    17581 gtgtaccatc gtggagcaaa tataaaactc catcagatga tgaacacaca tccagttcta
    17641 caccccagta tccgattttt gacgcttcat caattgcagg aatagaattt tcaggggcag
    17701 caccacttgc agcacggtga gctattataa ctggtttgtt aaaatttaga tttatagaag
    17761 tataaattgg ttttgctgat gtatatttta aattaatggt tttgggattt ttacttatgg
    17821 tagatacttt tattgttgta ttatataaac tttttaaagt atttttatta ttattattgc
    17881 accttaaaat tggattagct attgatgaaa tcatcagatt aataaataat agtattataa
    17941 ttttataaat aatatcaccc tccctattac ataaaatagt tgatgtaatt aattttgcat
    18001 ataagcctat tatatattag aaattgcatg ttttatttac aaaaatatta cttatacgac
    18061 taatttgttt acaaaactgt gacattaact aaaaattcta tgcttacagg aaaaaatagg
    18121 agtatattaa actgattact tttagtaacc attgttatat acatcacatt caaggttatt
    18181 tttgaaatat aatgatataa tttatttaat atagtatctc ttgtaaattt cgatattcaa
    18241 tagttatgat aaagaaagga atgccaaaga tgaaaattac aatacgtaag tatattgata
    18301 aagacatacc atgcattaca aggatctgga ataatatagt tgaagaagca aaagcatttc
    18361 ctcaaataga aaaaatgagt gaaaaggagg cagaaatatt ttttgcatct cagtcattta
    18421 cagcagttgc tgtttgtgat aatcaaattt tgggattgta tattttacac cccaataata
    18481 ttggacgctg tagtcatatt gcaaatgctt catatgctgt ttgtgcaaat tatagggggg
    18541 agcatattgg agaaaagttg gtgcgccatt ctatggacaa ggcaagggaa ttgaattttt
    18601 ccattcttca gtttaatgct gttgtaagta caaatcaaag tgcgattcat ctgtatgaaa
    18661 agataggatt taatcgtatt ggtattattc ctgctggtta cttgcttggt gatggaagtt
    18721 atacggatat aattttatat tatattccat taatataatt ttattttggt aggctgttaa
    18781 atagttattt tcataagcag gcatatgcta attgttcttt aacaatattc ataaaatggt
    18841 ataaattgtt tacaaatact taaccaatat gacattaagc cgtaacaaaa actatataga
    18901 ataataagtg tcctaaggaa ataccttaga gaaaacggaa ataatgcttt tacataaatg
    18961 aataaaagta atggtaatta ccagactggt gcctgtggtt gcagggcaca ccaaacttaa
    19021 gtgcaaccgc cattagatac caataattgt tgttctccca acaatatatt acaaaatgag
    19081 cattcgtcat ttagggtgct catttttatg tattgtttat atatctaatt gccttgctat
    19141 tgttgcctgg gaaacgaaac tattatataa tacgattaag tgtcaacaga ttggaggaca
    19201 agcaatgaac aaagaagaac gggcaatgaa gggtttatgg gacatattta aaaaaagaat
    19261 atggcttgat agctttaaga tgaaagatag gcttaagggt tataatcctt ctgaaataca
    19321 ttgtattgct tatataggag aagatgaaga ttccaacgtg acaaagctgg cggagtcttt
    19381 tggcatgacc agaggtgcca taagcaaact aactaagaaa ctcgtaaaaa aagggcttat
    19441 agaaagttat cagaagccga ataataataa agaagtctat tttgaactca ctgagcaagg
    19501 aaaaacaatt tacgatatcc atgaggaaat gcacagagag tttaaggata gagatcaacc
    19561 cttttttgaa caagtaacag aggaacagct tgatattata ctcggcttcg cgaaaaagta
    19621 taatatgcat ttggacacgg aaataaagaa actgggtgta gatatgaaat ctgataacct
    19681 atagttttac ggactctcct tgaaacatat taagaaacaa caaatttccg gcagctctcc
    19741 cttattgagg atgggctgca tttttgtgcg tctttaaatt cacagacttt attgtttcct
    19801 cttcaatatt gatattgaca aggaaacaat gagatgataa aataattatg ttgacaagga
    19861 aacaaaaatg ccgttataag aggagatcgt acaatgaaca tacaatccgc ataacaaacg
    19921 gaaaacaaaa ctgatatgca aggaggaaaa agcatgaata tcatcggaat tatcgcaagt
    19981 cagcgtaaag aaggcaatac tgcttttatt gtaaataaaa tactcgaagg tgcaaaggaa
    20041 cagggtgccc agacgagtac tttcagtttc agcgatcttg atatcaaacc atgctgtgga
    20101 tgttgggctt gccacaacgg cgatcagggg tgtgttatca acgacgatat gcagaaaatt
    20161 tatgatgcac ttgagtatgc agatgccatt gttttaggct caccgattta catgggtcag
    20221 atgagtgccc aaggcaagat atttaccgat aggttgtttg cacggttttc cccgcgattc
    20281 tctccgtttt tcaaagaaaa tgctgtgaaa caaaagctga ttctttcatt taatcaaggt
    20341 aatcctgatg ctggcctgtt caaatcttat attgattata cgaaacacat gtttgaggta
    20401 ctggaatttg atgctgaaga ggtacctgtt gttacaggtt tgcgaaatgg gccggtgcat
    20461 gaaagagaag atctgtgcac gagcctgaag aattttggat cagtgttggt tttggaagga
    20521 tgccagaaat aa
//
