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Overview
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1.2
1.3
1.4

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP014170.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | cyclic-lactone-autoinducer | 244,780 | 265,311 |
Region 1.2 | ranthipeptide | 917,998 | 939,584 |
Region 1.3 | cyclic-lactone-autoinducer | 1,169,435 | 1,191,529 |
Region 1.4 | RiPP-like | 2,223,238 | 2,233,474 |

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | cyclic-lactone-autoinducer | 244,780 | 265,311 |
Region 1.2 | ranthipeptide | 917,998 | 939,584 |
Region 1.3 | cyclic-lactone-autoinducer | 1,169,435 | 1,191,529 |
Region 1.4 | RiPP-like | 2,223,238 | 2,233,474 |

No secondary metabolite regions were found in these records:
  NZ_CP014171.1

Compact view
NZ_CP014170.1 - Region 1 - cyclic-lactone-autoinducer
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 244,780 - 265,311 nt. (total: 20,532 nt) Show pHMM detection rules used
cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | cyclic-lactone-autoinducer | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000780.1 |  | 0.17 | Saccharide | O&K-antigen | Vibrio parahaemolyticus
BGC0000678.1 |  | 0.06 | Terpene | pentalenolactone | Streptomyces avermitilis MA-4680 = NBRC 14893
BGC0001483.1 |  | 0.06 | Other | 5-isoprenylindole-3-carboxylate β-D-glycosyl ester | Streptomyces sp. RM-5-8
BGC0002007.1 |  | 0.05 | Terpene | atolypene A, atolypene B | Amycolatopsis tolypomycina
BGC0000080.1 |  | 0.05 | Polyketide | jerangolid A, jerangolid D | Sorangium cellulosum
BGC0000653.1 |  | 0.04 | Terpene | pentalenolactone | Streptomyces arenae
BGC0001283.1 |  | 0.04 | Polyketide | arsono-polyketide | Streptomyces lividans 1326
BGC0001995.1 |  | 0.04 | Terpene | heptelidic acid | Aspergillus oryzae RIB40
BGC0001555.1 |  | 0.03 | RiPP | colicin V | Escherichia coli chi7122

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000780.1 |  | 0.48 | Saccharide | O&K-antigen | Vibrio parahaemolyticus
BGC0000678.1 |  | 0.27 | Terpene | pentalenolactone | Streptomyces avermitilis MA-4680 = NBRC 14893
BGC0001483.1 |  | 0.26 | Other | 5-isoprenylindole-3-carboxylate β-D-glycosyl ester | Streptomyces sp. RM-5-8
BGC0002007.1 |  | 0.21 | Terpene | atolypene A, atolypene B | Amycolatopsis tolypomycina
BGC0000080.1 |  | 0.21 | Polyketide | jerangolid A, jerangolid D | Sorangium cellulosum
BGC0000653.1 |  | 0.19 | Terpene | pentalenolactone | Streptomyces arenae
BGC0001283.1 |  | 0.18 | Polyketide | arsono-polyketide | Streptomyces lividans 1326
BGC0001995.1 |  | 0.18 | Terpene | heptelidic acid | Aspergillus oryzae RIB40
BGC0001555.1 |  | 0.17 | RiPP | colicin V | Escherichia coli chi7122

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP014170.1 - Region 2 - ranthipeptide
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 917,998 - 939,584 nt. (total: 21,587 nt) Show pHMM detection rules used
ranthipeptide: (TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085 or SPASM)) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716 or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or YcaO or TIGR03882)))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | ranthipeptide | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000599.1 |  | 0.15 | RiPP | thuricin CD α, thuricin CD β | Bacillus thuringiensis
BGC0001120.1 |  | 0.14 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0002026.1 |  | 0.07 | NRP | thaxteramide A1, thaxteramide A2, thaxteramide B1, thaxteramide B2 | Jahnella sp. MSr9139
BGC0001579.1 |  | 0.07 | RiPP | duramycin | Streptomyces cinnamoneus
BGC0001298.1 |  | 0.06 | Polyketide | 4-Z-annimycin | Streptomyces calvus
BGC0001591.1 |  | 0.05 | Other | fatty acid enol ester | uncultured bacterium CSLC2
BGC0001688.1 |  | 0.05 | Other | N-tetradecanoyl tyrosine | uncultured bacterium CSLC2
BGC0000027.1 |  | 0.05 | Polyketide | ankaflavin, monascin, rubropunctatine, monascorubrin | Monascus pilosus
BGC0000503.1 |  | 0.04 | RiPP | cinnamycin | Streptomyces cinnamoneus
BGC0001089.1 |  | 0.04 | Polyketide, NRP | bacillaene | Bacillus velezensis FZB42

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000599.1 |  | 0.46 | RiPP | thuricin CD α, thuricin CD β | Bacillus thuringiensis
BGC0001120.1 |  | 0.43 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0002026.1 |  | 0.28 | NRP | thaxteramide A1, thaxteramide A2, thaxteramide B1, thaxteramide B2 | Jahnella sp. MSr9139
BGC0001579.1 |  | 0.27 | RiPP | duramycin | Streptomyces cinnamoneus
BGC0001298.1 |  | 0.27 | Polyketide | 4-Z-annimycin | Streptomyces calvus
BGC0001591.1 |  | 0.23 | Other | fatty acid enol ester | uncultured bacterium CSLC2
BGC0001688.1 |  | 0.23 | Other | N-tetradecanoyl tyrosine | uncultured bacterium CSLC2
BGC0000027.1 |  | 0.21 | Polyketide | ankaflavin, monascin, rubropunctatine, monascorubrin | Monascus pilosus
BGC0000503.1 |  | 0.19 | RiPP | cinnamycin | Streptomyces cinnamoneus
BGC0001089.1 |  | 0.17 | Polyketide, NRP | bacillaene | Bacillus velezensis FZB42

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP014170.1 - Region 3 - cyclic-lactone-autoinducer
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,169,435 - 1,191,529 nt. (total: 22,095 nt) Show pHMM detection rules used
cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | cyclic-lactone-autoinducer | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000521.1 |  | 0.17 | RiPP | lacticin 481 | Lactococcus lactis subsp. lactis
BGC0000539.1 |  | 0.17 | RiPP | nukacin ISK-1 | Staphylococcus warneri
BGC0001391.1 |  | 0.16 | RiPP | thusin | Bacillus thuringiensis serovar rongseni
BGC0000523.1 |  | 0.16 | RiPP | lactocin S | Lactobacillus sakei
BGC0001210.1 |  | 0.16 | RiPP | pseudomycoicidin | Bacillus pseudomycoides DSM 12442
BGC0000563.1 |  | 0.16 | RiPP | venezuelin | Streptomyces venezuelae ATCC 10712
BGC0000542.1 |  | 0.16 | RiPP | paenicidin B | Paenibacillus terrae
BGC0000555.1 |  | 0.16 | RiPP | staphylococcin C55 α, staphylococcin C55 β | Staphylococcus aureus
BGC0000541.1 |  | 0.16 | RiPP | paenicidin A | Paenibacillus polymyxa
BGC0000626.1 |  | 0.16 | RiPP | thuricin | Bacillus thuringiensis

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000521.1 |  | 0.48 | RiPP | lacticin 481 | Lactococcus lactis subsp. lactis
BGC0000539.1 |  | 0.48 | RiPP | nukacin ISK-1 | Staphylococcus warneri
BGC0001391.1 |  | 0.47 | RiPP | thusin | Bacillus thuringiensis serovar rongseni
BGC0000523.1 |  | 0.47 | RiPP | lactocin S | Lactobacillus sakei
BGC0001210.1 |  | 0.47 | RiPP | pseudomycoicidin | Bacillus pseudomycoides DSM 12442
BGC0000563.1 |  | 0.47 | RiPP | venezuelin | Streptomyces venezuelae ATCC 10712
BGC0000542.1 |  | 0.47 | RiPP | paenicidin B | Paenibacillus terrae
BGC0000555.1 |  | 0.47 | RiPP | staphylococcin C55 α, staphylococcin C55 β | Staphylococcus aureus
BGC0000541.1 |  | 0.47 | RiPP | paenicidin A | Paenibacillus polymyxa
BGC0000626.1 |  | 0.47 | RiPP | thuricin | Bacillus thuringiensis

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP014170.1 - Region 4 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,223,238 - 2,233,474 nt. (total: 10,237 nt) Show pHMM detection rules used
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RiPP-like | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000386.1 |  | 0.16 | NRP | malleobactin A, malleobactin B, malleobactin C, malleobactin D | Burkholderia thailandensis E264
BGC0001654.1 |  | 0.16 | Saccharide | lipooligosaccharide | Bacteroides thetaiotaomicron VPI-5482
BGC0001586.1 |  | 0.15 | Saccharide | EPS273 | Pseudomonas stutzeri
BGC0000776.1 |  | 0.14 | Saccharide | lipopolysaccharide | Escherichia coli
BGC0000765.1 |  | 0.13 | Saccharide | exopolysaccharide | Lactobacillus johnsonii
BGC0000796.1 |  | 0.08 | Saccharide | S-layer glycan | Paenibacillus alvei
BGC0001009.1 |  | 0.04 | NRP, Polyketide | melithiazol A | Melittangium lichenicola
BGC0001010.1 |  | 0.04 | NRP, Polyketide | melithiazol A | Melittangium lichenicola
BGC0001096.1 |  | 0.03 | NRP, Polyketide | FR901464 | Pseudomonas sp. 2663
BGC0000995.1 |  | 0.03 | NRP, Polyketide | FR901464 | Pseudomonas sp. 2663

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000386.1 |  | 0.47 | NRP | malleobactin A, malleobactin B, malleobactin C, malleobactin D | Burkholderia thailandensis E264
BGC0001654.1 |  | 0.47 | Saccharide | lipooligosaccharide | Bacteroides thetaiotaomicron VPI-5482
BGC0001586.1 |  | 0.46 | Saccharide | EPS273 | Pseudomonas stutzeri
BGC0000776.1 |  | 0.43 | Saccharide | lipopolysaccharide | Escherichia coli
BGC0000765.1 |  | 0.42 | Saccharide | exopolysaccharide | Lactobacillus johnsonii
BGC0000796.1 |  | 0.30 | Saccharide | S-layer glycan | Paenibacillus alvei
BGC0001009.1 |  | 0.21 | NRP, Polyketide | melithiazol A | Melittangium lichenicola
BGC0001010.1 |  | 0.21 | NRP, Polyketide | melithiazol A | Melittangium lichenicola
BGC0001096.1 |  | 0.16 | NRP, Polyketide | FR901464 | Pseudomonas sp. 2663
BGC0000995.1 |  | 0.16 | NRP, Polyketide | FR901464 | Pseudomonas sp. 2663

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names