LOCUS       NZ_CP072983.1          22526 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP072983.1 Lactobacillus intestinalis strain DSM 6629 chromosome,
            complete genome.
ACCESSION   NZ_CP072983
VERSION     NZ_CP072983.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:36:57
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1389661
            Orig. end    :: 1412187
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22526
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[1399661:1402187](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12526)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
     cand_cluster    1..22526
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /kind="single"
                     /product="lanthipeptide-class-iv"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..22526
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iv"
                     /region_number="3"
                     /rules="(cds(LANC_like and Pkinase) and not micKC)"
                     /tool="antismash"
     CDS             complement(943..1494)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111:GCN5-related N-acetyltransferase (Score: 70.3;
                     E-value: 3.1e-21)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1256"
                     /transl_table=11
                     /translation="MLASKRIYLRNVSENDAPILLKWGKDKSYHDSAGFGSYENLAEAK
                     KAAKQYIMRKNSYLICLKENDQVVGLIELNERGMDERSGLLKTKELGFLMDKDYRQKGL
                     MTEAIDLVVKDAFINLDQNEIWAGTFENNLKSQNLLKKLGFKYIYEIDYSQISDLFSYK
                     EKYYLLKKTEWLKIEQNTKS"
     PFAM_domain     complement(1057..1479)
                     /aSDomain="Acetyltransf_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13302.9"
                     /description="Acetyltransferase (GNAT) domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1256_0031"
                     /evalue="3.70E-20"
                     /label="ctg1_1256"
                     /locus_tag="ctg1_1256"
                     /protein_end="146"
                     /protein_start="5"
                     /score="73.1"
                     /tool="antismash"
                     /translation="RIYLRNVSENDAPILLKWGKDKSYHDSAGFGSYENLAEAKKAAKQ
                     YIMRKNSYLICLKENDQVVGLIELNERGMDERSGLLKTKELGFLMDKDYRQKGLMTEAI
                     DLVVKDAFINLDQNEIWAGTFENNLKSQNLLKKLGFK"
     CDS             complement(1494..2099)
                     /locus_tag="ctg1_1257"
                     /transl_table=11
                     /translation="MHLSAKTSRKLINYATIICGIIIILLVIYWYRLGIFTNQEKMKAY
                     LQNKQIIGPIVFVLIQIVQVVIPIIPGGVSLLGGVVFFGPVAGFLYNYVGICIGSIINF
                     FLARYYGRSFIFHIVSEETLNKYMKWTKNQKKFNWFFALCILAPAAPDDVLCLLAGLTE
                     MKFWTYFWIIILCKPWTIAAYSIGLVYGANWLLKLVGK"
     PFAM_domain     complement(1542..1892)
                     /aSDomain="SNARE_assoc"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09335.13"
                     /description="SNARE associated Golgi protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1257_0032"
                     /evalue="4.10E-22"
                     /label="ctg1_1257"
                     /locus_tag="ctg1_1257"
                     /protein_end="186"
                     /protein_start="69"
                     /score="79.0"
                     /tool="antismash"
                     /translation="IPGGVSLLGGVVFFGPVAGFLYNYVGICIGSIINFFLARYYGRSF
                     IFHIVSEETLNKYMKWTKNQKKFNWFFALCILAPAAPDDVLCLLAGLTEMKFWTYFWII
                     ILCKPWTIAAYSI"
     CDS             2269..3063
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1066:alpha/beta hydrolase domain-containing protein
                     (Score: 87.2; E-value: 1.7e-26)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1258"
                     /sec_met_domain="Peptidase_S9 (E-value: 7.2e-06, bitscore:
                     22.1, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVVIKNDITYDSEKKLKTDIYYPNDTTSATKILIFWHGGGWFRGS
                     KDDAKKVGVNLANAGFMTFIPDYSLAPEHVFPEAHDDAVHFVKWLLNSNYTDKDDQKNI
                     VQIGASVGGTLALYVAGKYGFPTVTWSAPVEFSKWMKNHENVKPSYEGAKEFGLTDLHD
                     INNSFYKYFTLTYAGTADQKVLKKLDADSYDYSHLKELMMINSADELNPLPNVLNFIQF
                     LADQNLGVELLVIKGHRHAMAYASDYIDESLDFLYQTIKRQK"
     PFAM_domain     2365..2994
                     /aSDomain="Abhydrolase_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07859.15"
                     /description="alpha/beta hydrolase fold"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1258_0033"
                     /evalue="3.60E-20"
                     /label="ctg1_1258"
                     /locus_tag="ctg1_1258"
                     /protein_end="242"
                     /protein_start="32"
                     /score="72.8"
                     /tool="antismash"
                     /translation="LIFWHGGGWFRGSKDDAKKVGVNLANAGFMTFIPDYSLAPEHVFP
                     EAHDDAVHFVKWLLNSNYTDKDDQKNIVQIGASVGGTLALYVAGKYGFPTVTWSAPVEF
                     SKWMKNHENVKPSYEGAKEFGLTDLHDINNSFYKYFTLTYAGTADQKVLKKLDADSYDY
                     SHLKELMMINSADELNPLPNVLNFIQFLADQNLGVELLVIKGHRHAM"
     CDS             3066..3935
                     /locus_tag="ctg1_1259"
                     /transl_table=11
                     /translation="MINIDKFIKIRKSKKISQNELSHGICTQSTLSKFENNGQVPSFKI
                     LKQLCDRMGIEVGDIIRQSSDNPATKNMFEAEFAFITYDYNKIRDLLSSIHEQDLKHEQ
                     DRLHFDYLRGLYALDGEKNDMTALYYFNNILSNRDIADNNIYRLLALNGCSQIYASEND
                     MAKAHHYYDQILSYIKDIDIDDELTALQVLAILCDAGEFFGKQKEYKKSNSLLRYAYSI
                     ASEKHTVYFLARILFRWGLNDIEQGKGLDKALQHLYDACAFARLNKNHVILTKAKKLIK
                     ELNQKNVD"
     PFAM_domain     3090..3239
                     /aSDomain="HTH_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01381.24"
                     /description="Helix-turn-helix"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1259_0034"
                     /evalue="4.50E-08"
                     /label="ctg1_1259"
                     /locus_tag="ctg1_1259"
                     /protein_end="58"
                     /protein_start="8"
                     /score="33.1"
                     /tool="antismash"
                     /translation="KIRKSKKISQNELSHGICTQSTLSKFENNGQVPSFKILKQLCDRM
                     GIEVG"
     CDS             complement(3951..4454)
                     /locus_tag="ctg1_1260"
                     /transl_table=11
                     /translation="MTAEISTAKIYLGSPFYNDAQRERVTKARKLLAQNPTVWQVHFPF
                     DQNFVDPEEKNPEIGGVRSMTWRVATYQNDLNGIVNATCGVFLYDMDNIDDGSAFEIGF
                     FRALHKPVILVPFTEIENKEKEMNLMLAQGVTTIIDGNDSFEKLASYDFNSCPADPVVG
                     YKII"
     PFAM_domain     complement(4065..4427)
                     /aSDomain="Nuc_deoxyrib_tr"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05014.17"
                     /description="Nucleoside 2-deoxyribosyltransferase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1260_0035"
                     /evalue="6.00E-22"
                     /label="ctg1_1260"
                     /locus_tag="ctg1_1260"
                     /protein_end="130"
                     /protein_start="9"
                     /score="78.1"
                     /tool="antismash"
                     /translation="IYLGSPFYNDAQRERVTKARKLLAQNPTVWQVHFPFDQNFVDPEE
                     KNPEIGGVRSMTWRVATYQNDLNGIVNATCGVFLYDMDNIDDGSAFEIGFFRALHKPVI
                     LVPFTEIENKEKEMNLM"
     CDS             complement(4645..5802)
                     /gene_functions="other (smcogs) SMCOG1192:transposase
                     (Score: 206.5; E-value: 1.1e-62)"
                     /gene_kind="other"
                     /locus_tag="ctg1_1261"
                     /transl_table=11
                     /translation="MIKTQVVKLKVNKTMQKHLDTLCDYRRYCWNKGLETWQLMYEAHT
                     LNKKDNPNPNERRVRDELVANKADWQYNLSARCLQLAVKDLANAWKNFFDKAQPDWGKP
                     RFRSKKAPRQGFKTDRAKIVNGKLRLDRPRSISRDSWFDLASYEVLKMDEVKVVSIFKE
                     KDSYYASLPYEEDILAKTKTHNKTAIDVNVGHFNYTEGQIIVLPAKLQKLYKRIKHYQR
                     MLARKRKVNGKLAAKSNNYFAVRTKLQRNYRRVANIQNDLLQKFTTKLVNDYDQIVIED
                     LAIKQMMMTHVASKGMQRSLFGKFRQILTYKCDWYGKELILAEKTYPSTQRCAQCGYVK
                     KGDEKITLQGNKKHGTKHNEYICYECGYSNDRDENAVLNLLALAN"
     PFAM_domain     complement(4660..4899)
                     /aSDomain="OrfB_Zn_ribbon"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07282.13"
                     /description="Putative transposase DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1261_0037"
                     /evalue="5.80E-15"
                     /label="ctg1_1261"
                     /locus_tag="ctg1_1261"
                     /protein_end="381"
                     /protein_start="301"
                     /score="55.1"
                     /tool="antismash"
                     /translation="FGKFRQILTYKCDWYGKELILAEKTYPSTQRCAQCGYVKKGDEKI
                     TLQGNKKHGTKHNEYICYECGYSNDRDENAVLNLL"
     aSDomain        complement(4816..5034)
                     /aSDomain="TIGR01766"
                     /aSTool="tigrfam"
                     /description="tspaseT_teng_C: transposase, IS605 OrfB
                     family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1261_0011"
                     /evalue="3.70E-12"
                     /identifier="TIGR01766"
                     /label="ctg1_1261"
                     /locus_tag="ctg1_1261"
                     /protein_end="329"
                     /protein_start="256"
                     /score="44.6"
                     /tool="antismash"
                     /translation="NIQNDLLQKFTTKLVNDYDQIVIEDLAIKQMMMTHVASKGMQRSL
                     FGKFRQILTYKCDWYGKELILAEKTYPS"
     PFAM_domain     complement(4939..5292)
                     /aSDomain="OrfB_IS605"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01385.21"
                     /description="Probable transposase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1261_0036"
                     /evalue="1.50E-14"
                     /label="ctg1_1261"
                     /locus_tag="ctg1_1261"
                     /protein_end="288"
                     /protein_start="170"
                     /score="54.4"
                     /tool="antismash"
                     /translation="LPYEEDILAKTKTHNKTAIDVNVGHFNYTEGQIIVLPAKLQKLYK
                     RIKHYQRMLARKRKVNGKLAAKSNNYFAVRTKLQRNYRRVANIQNDLLQKFTTKLVNDY
                     DQIVIEDLAIKQMM"
     CDS             6101..7483
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017:aldehyde dehydrogenase (Score: 369.1; E-value:
                     4.4e-112)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1262"
                     /transl_table=11
                     /translation="MSRYQSINPYNGDVFATFENPTDKEIEESLNLAHMLYKKWRHEDP
                     STRSKELLAIAGGFRENEDKMAQMMTLEIGKLFSEAKEEVELCIQICEYYAVNGADMLK
                     PQPLESGLGNAYYLKQPTGVVLACEPWNFPLYQVIRVFAPNFMVGNPIILKHAHNVPSS
                     AALMAKIIKRAGAPEGSLINLYLSYDQLAQVIRDPRIQGVALTGSERGGSSVAEEAGKN
                     LKKSTMELGGNDPFIVLEDADKDVLRNVLSDARTYNDGQVCTSSKRIIVVKSRYEEVLR
                     ELKSLYEVLKPGDPLDSSTTLAPMNSEGAKEKLEKQVQEAVDHGAQIYYQHPEIESTGA
                     FFPPTILTHIGKDNPVFDKELFGPVAEVHCVEDEDEAIKLANDSSYGLGSSIISKNTAH
                     AEKLAAKIETGMTVINGRWVTAPELPFGGVKKSGYGRELGKLGLMAFVNEHLVIDTTSE
                     NE"
     PFAM_domain     6107..7444
                     /aSDomain="Aldedh"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00171.24"
                     /description="Aldehyde dehydrogenase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1262_0038"
                     /evalue="4.40E-121"
                     /label="ctg1_1262"
                     /locus_tag="ctg1_1262"
                     /protein_end="448"
                     /protein_start="2"
                     /score="404.7"
                     /tool="antismash"
                     /translation="RYQSINPYNGDVFATFENPTDKEIEESLNLAHMLYKKWRHEDPST
                     RSKELLAIAGGFRENEDKMAQMMTLEIGKLFSEAKEEVELCIQICEYYAVNGADMLKPQ
                     PLESGLGNAYYLKQPTGVVLACEPWNFPLYQVIRVFAPNFMVGNPIILKHAHNVPSSAA
                     LMAKIIKRAGAPEGSLINLYLSYDQLAQVIRDPRIQGVALTGSERGGSSVAEEAGKNLK
                     KSTMELGGNDPFIVLEDADKDVLRNVLSDARTYNDGQVCTSSKRIIVVKSRYEEVLREL
                     KSLYEVLKPGDPLDSSTTLAPMNSEGAKEKLEKQVQEAVDHGAQIYYQHPEIESTGAFF
                     PPTILTHIGKDNPVFDKELFGPVAEVHCVEDEDEAIKLANDSSYGLGSSIISKNTAHAE
                     KLAAKIETGMTVINGRWVTAPELPFGGVKKSGYGRELGKLGLMAFVN"
     CDS             complement(7543..8211)
                     /locus_tag="ctg1_1263"
                     /transl_table=11
                     /translation="LEFDIVKTVNNYDDAINFIEKVSFKSGIYFLDIEIGKKLYEKNGL
                     DLAEIIKKRDKNAQLIFITSHQDMAFLTFKRKLGAVDFIIKNGNVGDLQKDVNYALQSA
                     TKAISNADFIKKNTFSYKFGQEVRNINLGDVIYITTTSVGHKLKLIKTTGWGYFIGNLK
                     EIPEKYGSLVQISQSCVINPENVDRVNFREKKIGFVNGESQYYSVRNTHKMHKLFKNKF
                     "
     PFAM_domain     complement(7558..7833)
                     /aSDomain="LytTR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04397.17"
                     /description="LytTr DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1263_0040"
                     /evalue="5.50E-09"
                     /label="ctg1_1263"
                     /locus_tag="ctg1_1263"
                     /protein_end="218"
                     /protein_start="126"
                     /score="36.2"
                     /tool="antismash"
                     /translation="VRNINLGDVIYITTTSVGHKLKLIKTTGWGYFIGNLKEIPEKYGS
                     LVQISQSCVINPENVDRVNFREKKIGFVNGESQYYSVRNTHKMHKLF"
     PFAM_domain     complement(7921..8202)
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1263_0039"
                     /evalue="6.50E-11"
                     /label="ctg1_1263"
                     /locus_tag="ctg1_1263"
                     /protein_end="97"
                     /protein_start="3"
                     /score="42.5"
                     /tool="antismash"
                     /translation="DIVKTVNNYDDAINFIEKVSFKSGIYFLDIEIGKKLYEKNGLDLA
                     EIIKKRDKNAQLIFITSHQDMAFLTFKRKLGAVDFIIKNGNVGDLQKDV"
     CDS             complement(8333..9661)
                     /locus_tag="ctg1_1264"
                     /transl_table=11
                     /translation="MLLAIINIFFIGPAVDILIFLNITKLRVKSIFDRFVLIGLGITVI
                     LLESISDFIKLDQTDLIFTIIEASLFEIVFYKRVKDKILLVNAGIIVAMLSLISDFVIT
                     ISENLSFTNTALVEFMSMLLPIIEYIVIRHYSSKLNRLFSGINKKTIFYTLLYLYISTA
                     IAYIVATLEKQVTIETLTILGILVIQGVYAIVSLKLNLQLQTTLLEKAEQQKLKDVNHQ
                     LEKNNKQLKDYATSLEKDEDRLRRFKHDYRNILNGLKIAAQKDDSKALIKQLDEYSQNH
                     FDENTLSKFKDVHHIHNDMIKSIIITKLAKIYDDKIPYRFSCEKDIIDFPFISKDEELD
                     IVRIIGIAFDNAIEASEGLKNAQIEAMLYQSEGNLEFIIRNKIDQVDKDQILKAGFTTK
                     NDHNGLGLSNAMEIANKYFENIMVDVDTKGEWFTFSLVLLPTN"
     PFAM_domain     complement(8348..8653)
                     /aSDomain="HATPase_c_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14501.8"
                     /description="GHKL domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1264_0041"
                     /evalue="6.20E-15"
                     /label="ctg1_1264"
                     /locus_tag="ctg1_1264"
                     /protein_end="438"
                     /protein_start="336"
                     /score="55.0"
                     /tool="antismash"
                     /translation="EELDIVRIIGIAFDNAIEASEGLKNAQIEAMLYQSEGNLEFIIRN
                     KIDQVDKDQILKAGFTTKNDHNGLGLSNAMEIANKYFENIMVDVDTKGEWFTFSLVL"
     CDS             complement(9661..9780)
                     /locus_tag="ctg1_1265"
                     /transl_table=11
                     /translation="MKKIKLIEVNGLFNPYVSFFSKKTAEKHKVMQFLKRLFK"
     CDS             complement(9849..9998)
                     /locus_tag="ctg1_1266"
                     /transl_table=11
                     /translation="MHDENQDILNLQGTTPFVSLARRRGHGGTKNYNFSLFCWNHIKTI
                     FHLK"
     CDS             complement(10001..12526)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: Pkinase"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1030:serine/threonine protein kinase (Score: 55.7;
                     E-value: 9.1e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1267"
                     /sec_met_domain="LANC_like (E-value: 7.3e-14, bitscore:
                     47.8, seeds: 47, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 7.5e-17, bitscore: 58.1,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYNIEGYLPFTLNDKDFFSEPNKKANEFKVKVPQGWRQFSDLHW
                     QYFLNSKAKLPDQGWKIHLSAGYKDIEQLLQTVTKYLVDKGVTFKVTIGKEEWILKNSK
                     SADRVSSGKFITIYPQNDQEFKEIVHDVSKKIASFEIGPYILSDKRYKNTNIYYRYGAF
                     TELRNDQGILCIRDENGNLIPDSRQPFYQQPNFVEDPLMDEQDISQLRIANKEKLDKYH
                     ITGALQFSNAGGVYVGEFQNKNYVLKEGRLQAGIDSNYEDGFSRIKHESDILKKLQNSP
                     YVVNFKEYFPVWIHNYLVEEYLPYENLGDYITDNFPFHGENSEYLNIIKEIAHNLIKAI
                     KDVHSRGIAVGDLQPDNILINENKNVILIDFEQANNKTEKYNPGLKTTGFVDLDVQTYG
                     EADWIAVYKTIRHAFLPIINIDELSDNTSESYQDQNLKKYDPAVYKFLMSFKKECYEKI
                     SLESYSLNQKAYFSLDLNNLEEAVKKIRQGIKNNLDFNQERILKGDISQYLSTIGMFNI
                     LNGGMGLGLILSDLNEGTRTQFLDWFEQNKAEIWKGIQKDSGLFTGAAGIGSVIYSNIN
                     KDLGKKIIDQIDYSQISSLSLKDGLAGIGLALLALNQVEPEFARQRKIKEIARNVNDNY
                     DECPSAGLLDGKLGLLLFLEKVAIYLQDSILFKSVESKVNFFIKNELHRTERGLYLMDE
                     THSNYLPYLNSGSAGLEIVILEFIKDGINIEDGRKLIESLSATNDVKLTYMNGIFDGFC
                     GLMLADLAAENYDYSNALQKKIHLLNNYLVIKKDEILVPGRHGLKNSMDLDSGAIGVLL
                     TLQGIIDNDWGQWLPIIHSAKLSILKGGE"
     PFAM_domain     complement(10082..10747)
                     /aSDomain="LANC_like"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05147.15"
                     /description="Lanthionine synthetase C-like protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1267_0043"
                     /evalue="8.30E-08"
                     /label="ctg1_1267"
                     /locus_tag="ctg1_1267"
                     /protein_end="815"
                     /protein_start="593"
                     /score="31.3"
                     /tool="antismash"
                     /translation="SLSLKDGLAGIGLALLALNQVEPEFARQRKIKEIARNVNDNYDEC
                     PSAGLLDGKLGLLLFLEKVAIYLQDSILFKSVESKVNFFIKNELHRTERGLYLMDETHS
                     NYLPYLNSGSAGLEIVILEFIKDGINIEDGRKLIESLSATNDVKLTYMNGIFDGFCGLM
                     LADLAAENYDYSNALQKKIHLLNNYLVIKKDEILVPGRHGLKNSMDLDSGAIGVLLTLQ
                     "
     PFAM_domain     complement(11384..11803)
                     /aSDomain="Pkinase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00069.27"
                     /description="Protein kinase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1267_0042"
                     /evalue="4.00E-15"
                     /label="ctg1_1267"
                     /locus_tag="ctg1_1267"
                     /protein_end="381"
                     /protein_start="241"
                     /score="56.0"
                     /tool="antismash"
                     /translation="NKNYVLKEGRLQAGIDSNYEDGFSRIKHESDILKKLQNSPYVVNF
                     KEYFPVWIHNYLVEEYLPYENLGDYITDNFPFHGENSEYLNIIKEIAHNLIKAIKDVHS
                     RGIAVGDLQPDNILINENKNVILIDFEQANNKTEKY"
     CDS             complement(12528..14243)
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 288; E-value: 2.5e-87)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_1268"
                     /transl_table=11
                     /translation="MKKENQISLFAVDRLLIIAILLSVIGSLFNLILPLFVQQFIDLGS
                     KVKFSISTLLPIILLLIGGSIINAVSSYLISYSGDKRIRNIRAKLEKKLLNLPISFYEK
                     VSSGELVSRVINDSLIIKEFTTNELPSAIISIVTLCGSVLILLILDVRLTFVIIISFTL
                     VSLIAYPLGKVNEKYSFSIQKYLSKLSQVITENIQNIKIIKLYNAQTEVENNFKKQNDK
                     VYSLSKKVDKIFSITGPIQTSFTLLAFLVIILYGSSRVAHHTLSMGILASFMMYVFEII
                     TPINNLANFYVSYSEAKGASQVINKIMEEKEERLQGRNIEHPHVADLKMKHIFFNYTDS
                     PIKVLKDVNVLFEPAKKIAIVGPSGAGKTTLTSILTRLQNTFDGEVLWNKIDAQIFSLK
                     AWRSLFSVVTQDNSVFSGTIKDNLTLGLGYDPSQMQLAEAIKLARLEKFISQLSNGLDF
                     EVGENGKKLSGGQRQKIQIARAYLRNTPFIIFDEATSNLDPESEAEILKAIDKLSEKKT
                     LIVIAHRLSTIVNADKIYFMDNHTILGVGKHSDLLHQIPKYKEFVNDQFISNEE"
     PFAM_domain     complement(12759..13211)
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1268_0045"
                     /evalue="1.00E-27"
                     /label="ctg1_1268"
                     /locus_tag="ctg1_1268"
                     /protein_end="495"
                     /protein_start="344"
                     /score="97.4"
                     /tool="antismash"
                     /translation="LKDVNVLFEPAKKIAIVGPSGAGKTTLTSILTRLQNTFDGEVLWN
                     KIDAQIFSLKAWRSLFSVVTQDNSVFSGTIKDNLTLGLGYDPSQMQLAEAIKLARLEKF
                     ISQLSNGLDFEVGENGKKLSGGQRQKIQIARAYLRNTPFIIFDEATS"
     PFAM_domain     complement(13410..14198)
                     /aSDomain="ABC_membrane"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00664.25"
                     /description="ABC transporter transmembrane region"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1268_0044"
                     /evalue="5.30E-46"
                     /label="ctg1_1268"
                     /locus_tag="ctg1_1268"
                     /protein_end="278"
                     /protein_start="15"
                     /score="157.6"
                     /tool="antismash"
                     /translation="LIIAILLSVIGSLFNLILPLFVQQFIDLGSKVKFSISTLLPIILL
                     LIGGSIINAVSSYLISYSGDKRIRNIRAKLEKKLLNLPISFYEKVSSGELVSRVINDSL
                     IIKEFTTNELPSAIISIVTLCGSVLILLILDVRLTFVIIISFTLVSLIAYPLGKVNEKY
                     SFSIQKYLSKLSQVITENIQNIKIIKLYNAQTEVENNFKKQNDKVYSLSKKVDKIFSIT
                     GPIQTSFTLLAFLVIILYGSSRVAHHTLSMGILASFMMYVF"
     CDS             complement(14246..14404)
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1269"
                     /transl_table=11
                     /translation="MENSNILNLQKLNVNGTSSQALLTSKRISVFCFNKHGKHKMRNIY
                     LPPILFA"
     CDS_motif       complement(14339..14404)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MENSNILNLQKLNVNGTSSQAL"
                     /locus_tag="ctg1_1269_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(14246..14338)
                     /prepeptide="core"
                     /locus_tag="ctg1_1269_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="-2.70"
                     /molecular_weight="3506.2"
                     /monoisotopic_mass="3504.0"
                     /core_sequence="LTSKRISVFCFNKHGKHKMRNIYLPPILFA"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MENSNILNLQKLNVNGTSSQAL"
                     /leader_location="[14338:14404](-)"
                     /alternative_weights="3524.2"
                     /alternative_weights="3542.3"
     CDS             complement(14416..14541)
                     /locus_tag="ctg1_1270"
                     /transl_table=11
                     /translation="MNSIINMQAYPTQATVEYFVKKRRKHRTSRTRVTIICWNIF"
     CDS             complement(14557..14697)
                     /locus_tag="ctg1_1271"
                     /transl_table=11
                     /translation="MENIINAILGLQKQREEKKHHKQSDGNNEVKHSLICFHDFSDWFK
                     F"
     CDS             complement(14889..15896)
                     /locus_tag="ctg1_1272"
                     /transl_table=11
                     /translation="MTTCPNCGQSVTKDDDICPKCGFNLKKYRDTFFEDDSEKKSVSSQ
                     PKRAQYREEFRPKKQNTTIQKMIAWVRSNATIVFLLGVVLLVIMSFSRALGWTSFLVLM
                     VWLFIVCDKADKIEQYTADKRLTEMINKMGSDVVNTAKEHTDKVRKKGKNFTETHPHVN
                     RHVEKVKERSKSKFSYIQLSVVLTSVISLIVLFTGSGAAVADVSYTQKLSLSKVILNLA
                     NRLLSSSHTSMSAIILYVFWLLLVLFPIFIIYNIFKNTKNSQFFAFILSLLETAFLIYI
                     VFKISNNSSNHGVIGELTNQFLMYAVSIGSSAYFLILASLLTTGLAGYNYFKKR"
     PFAM_domain     complement(15831..15896)
                     /aSDomain="zf-ribbon_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13248.8"
                     /description="zinc-ribbon domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1272_0046"
                     /evalue="1.10E-06"
                     /label="ctg1_1272"
                     /locus_tag="ctg1_1272"
                     /protein_end="22"
                     /protein_start="0"
                     /score="27.9"
                     /tool="antismash"
                     /translation="MTTCPNCGQSVTKDDDICPKCG"
     CDS             complement(16102..20007)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1035:MMPL domain-containing transport protein (Score:
                     466.5; E-value: 2.3e-141)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1273"
                     /transl_table=11
                     /translation="LQKFLKNHVFSLIAWILILLISVFALPNVSQLTSEHSTISLPSNV
                     QSEVAQTIQNQWGKKKKNTYEVAVVFNKEHGKLNDADKAAINNTVSYLENHKKKYGITD
                     VLAPDSNIATRKKLQSKDGTTWVMQLNISKKHGRIGEVEDQITKAVKTQGVRTYVTGAD
                     ILQNAFSTSIQEGIKKTEAITVVFIFIVLIIVFRSPIVPLISLLTVGVSFLTSFSIVTN
                     LVEHANFPFSNFTQVFMVIVLFGIGTDYNILLYDKFKEDLGKGMDKYEALRDSLRNAGK
                     TILYSGSSILIGFTALSLAKFSIYQSAVGVAVGVATLLVVLLTLNPFFMAVLGKNMFWP
                     VKEFTGESENKLWHGISAETLKYPVIYLVVLAVVTIPFMLMYHGQLNYDDTDEIADNVP
                     AKAGLLVVQKHFSKGMAEPSYLYIKSDHRLDNEANLKLIDQLTKQLQASKDVSFVTSVT
                     QPYGEPIDQLYVNNQLGTVNEGVDQARSGLGKLSKGSQKLSNGASRLQSGAEQLENGTG
                     RLQSGADQLRSGTTRLQNGASRLQSGADRLQNGAGTLQNGTQSLQNGADRLQSGASSLQ
                     NGTSSLVSGVGRLQAGAGRLASGTLALQNGASSLQSGAARLQNGAGNLRNGTQSLQNGT
                     QELVNGLNQLNNQLSTQLNGSNRAQLAQLQSALPQINNGIQALNTALNGAVDTSATTNG
                     LASVQRDAARLQSSLSKLQSLAGSAGSSSNTNASAAESAISGAVQKAVEGALSNSKATD
                     EEKAAAAQAGASAASSAVKQALSGNSGSSSSGELQSTLAEANSAAQGLQSSMQAMQQSN
                     TLNQIQALKTQVNALAAASNQAIPGAVTALNQLNSGLSQVQGAVTQGVAGANRLNSGVA
                     SLNSGAGQLYNGLGSLSLGASRLNSGAAQLNSGIGTLNTGLGSLSSGANRLNSGAGQLY
                     NGLGSLSSGASRLNSGAGQLYSGLGSLSSGAGQLNSGLAQGASGAEQLSNGIGQLNSGA
                     SQLSRGAGRLADSTPQLTSGIDRVNSGLGQGEAYLRGLGSSAAADTFYIPKEFINNAMF
                     QKSIDVYLSPNKKSAMLIVVFNSNPSAPEATARSQELSAMAKKSLQGTKLKNATVAMGG
                     QSSKIEDTKNVASGDFIRTAAIMLIGIGIALMFVTRSLLQPVYILGTLLIAYLCSLSIN
                     QWIVKLVLGRDLLTWNTPFFSFIMLIALGVDYSIFLMTRYRELETEGLTSPSARILKAC
                     GIIGTVVISAAVILGGTFAALIPSGIPTLIEVALTVIVGLIILVFIMPITMSAGVKLTY
                     EGFSGFKLGKHKHSMTK"
     PFAM_domain     complement(16192..16851)
                     /aSDomain="MMPL"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03176.17"
                     /description="MMPL family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1273_0048"
                     /evalue="6.70E-34"
                     /label="ctg1_1273"
                     /locus_tag="ctg1_1273"
                     /protein_end="1272"
                     /protein_start="1052"
                     /score="117.4"
                     /tool="antismash"
                     /translation="DVYLSPNKKSAMLIVVFNSNPSAPEATARSQELSAMAKKSLQGTK
                     LKNATVAMGGQSSKIEDTKNVASGDFIRTAAIMLIGIGIALMFVTRSLLQPVYILGTLL
                     IAYLCSLSINQWIVKLVLGRDLLTWNTPFFSFIMLIALGVDYSIFLMTRYRELETEGLT
                     SPSARILKACGIIGTVVISAAVILGGTFAALIPSGIPTLIEVALTVIVGLIILVFIM"
     aSDomain        complement(16960..17043)
                     /aSDomain="TIGR03057"
                     /aSTool="tigrfam"
                     /description="xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad
                     repeats"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1273_0025"
                     /evalue="1.70E-04"
                     /identifier="TIGR03057"
                     /label="ctg1_1273"
                     /locus_tag="ctg1_1273"
                     /protein_end="1016"
                     /protein_start="988"
                     /score="19.7"
                     /tool="antismash"
                     /translation="ASQLSRGAGRLADSTPQLTSGIDRVNSG"
     aSDomain        complement(17005..17082)
                     /aSDomain="TIGR03057"
                     /aSTool="tigrfam"
                     /description="xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad
                     repeats"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1273_0024"
                     /evalue="2.70E-06"
                     /identifier="TIGR03057"
                     /label="ctg1_1273"
                     /locus_tag="ctg1_1273"
                     /protein_end="1001"
                     /protein_start="975"
                     /score="25.4"
                     /tool="antismash"
                     /translation="EQLSNGIGQLNSGASQLSRGAGRLAD"
     aSDomain        complement(17149..17232)
                     /aSDomain="TIGR03057"
                     /aSTool="tigrfam"
                     /description="xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad
                     repeats"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1273_0023"
                     /evalue="1.90E-06"
                     /identifier="TIGR03057"
                     /label="ctg1_1273"
                     /locus_tag="ctg1_1273"
                     /protein_end="953"
                     /protein_start="925"
                     /score="25.9"
                     /tool="antismash"
                     /translation="AGQLYNGLGSLSSGASRLNSGAGQLYSG"
     aSDomain        complement(17191..17271)
                     /aSDomain="TIGR03057"
                     /aSTool="tigrfam"
                     /description="xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad
                     repeats"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1273_0022"
                     /evalue="4.50E-05"
                     /identifier="TIGR03057"
                     /label="ctg1_1273"
                     /locus_tag="ctg1_1273"
                     /protein_end="939"
                     /protein_start="912"
                     /score="21.5"
                     /tool="antismash"
                     /translation="GSLSSGANRLNSGAGQLYNGLGSLSSG"
     aSDomain        complement(17212..17292)
                     /aSDomain="TIGR03057"
                     /aSTool="tigrfam"
                     /description="xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad
                     repeats"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1273_0021"
                     /evalue="1.40E-06"
                     /identifier="TIGR03057"
                     /label="ctg1_1273"
                     /locus_tag="ctg1_1273"
                     /protein_end="932"
                     /protein_start="905"
                     /score="26.3"
                     /tool="antismash"
                     /translation="GTLNTGLGSLSSGANRLNSGAGQLYNG"
     aSDomain        complement(17275..17352)
                     /aSDomain="TIGR03057"
                     /aSTool="tigrfam"
                     /description="xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad
                     repeats"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1273_0020"
                     /evalue="5.90E-05"
                     /identifier="TIGR03057"
                     /label="ctg1_1273"
                     /locus_tag="ctg1_1273"
                     /protein_end="911"
                     /protein_start="885"
                     /score="21.1"
                     /tool="antismash"
                     /translation="SLSLGASRLNSGAAQLNSGIGTLNTG"
     aSDomain        complement(17359..17430)
                     /aSDomain="TIGR03057"
                     /aSTool="tigrfam"
                     /description="xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad
                     repeats"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1273_0019"
                     /evalue="3.80E-05"
                     /identifier="TIGR03057"
                     /label="ctg1_1273"
                     /locus_tag="ctg1_1273"
                     /protein_end="883"
                     /protein_start="859"
                     /score="21.8"
                     /tool="antismash"
                     /translation="VAGANRLNSGVASLNSGAGQLYNG"
     aSDomain        complement(18067..18147)
                     /aSDomain="TIGR03057"
                     /aSTool="tigrfam"
                     /description="xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad
                     repeats"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1273_0018"
                     /evalue="1.70E-04"
                     /identifier="TIGR03057"
                     /label="ctg1_1273"
                     /locus_tag="ctg1_1273"
                     /protein_end="647"
                     /protein_start="620"
                     /score="19.7"
                     /tool="antismash"
                     /translation="AGNLRNGTQSLQNGTQELVNGLNQLNN"
     aSDomain        complement(18211..18294)
                     /aSDomain="TIGR03057"
                     /aSTool="tigrfam"
                     /description="xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad
                     repeats"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1273_0017"
                     /evalue="8.10E-05"
                     /identifier="TIGR03057"
                     /label="ctg1_1273"
                     /locus_tag="ctg1_1273"
                     /protein_end="599"
                     /protein_start="571"
                     /score="20.7"
                     /tool="antismash"
                     /translation="ASSLQNGTSSLVSGVGRLQAGAGRLASG"
     aSDomain        complement(18295..18372)
                     /aSDomain="TIGR03057"
                     /aSTool="tigrfam"
                     /description="xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad
                     repeats"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1273_0016"
                     /evalue="2.70E-04"
                     /identifier="TIGR03057"
                     /label="ctg1_1273"
                     /locus_tag="ctg1_1273"
                     /protein_end="571"
                     /protein_start="545"
                     /score="19.1"
                     /tool="antismash"
                     /translation="RLQNGAGTLQNGTQSLQNGADRLQSG"
     aSDomain        complement(18358..18441)
                     /aSDomain="TIGR03057"
                     /aSTool="tigrfam"
                     /description="xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad
                     repeats"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1273_0015"
                     /evalue="2.00E-05"
                     /identifier="TIGR03057"
                     /label="ctg1_1273"
                     /locus_tag="ctg1_1273"
                     /protein_end="550"
                     /protein_start="522"
                     /score="22.6"
                     /tool="antismash"
                     /translation="ADQLRSGTTRLQNGASRLQSGADRLQNG"
     aSDomain        complement(18379..18459)
                     /aSDomain="TIGR03057"
                     /aSTool="tigrfam"
                     /description="xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad
                     repeats"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1273_0014"
                     /evalue="1.10E-05"
                     /identifier="TIGR03057"
                     /label="ctg1_1273"
                     /locus_tag="ctg1_1273"
                     /protein_end="543"
                     /protein_start="516"
                     /score="23.5"
                     /tool="antismash"
                     /translation="GRLQSGADQLRSGTTRLQNGASRLQSG"
     aSDomain        complement(18421..18504)
                     /aSDomain="TIGR03057"
                     /aSTool="tigrfam"
                     /description="xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad
                     repeats"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1273_0013"
                     /evalue="9.20E-06"
                     /identifier="TIGR03057"
                     /label="ctg1_1273"
                     /locus_tag="ctg1_1273"
                     /protein_end="529"
                     /protein_start="501"
                     /score="23.7"
                     /tool="antismash"
                     /translation="ASRLQSGAEQLENGTGRLQSGADQLRSG"
     aSDomain        complement(18442..18525)
                     /aSDomain="TIGR03057"
                     /aSTool="tigrfam"
                     /description="xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad
                     repeats"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1273_0012"
                     /evalue="2.30E-06"
                     /identifier="TIGR03057"
                     /label="ctg1_1273"
                     /locus_tag="ctg1_1273"
                     /protein_end="522"
                     /protein_start="494"
                     /score="25.6"
                     /tool="antismash"
                     /translation="SQKLSNGASRLQSGAEQLENGTGRLQSG"
     PFAM_domain     complement(18916..19851)
                     /aSDomain="MMPL"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03176.17"
                     /description="MMPL family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1273_0047"
                     /evalue="3.10E-55"
                     /label="ctg1_1273"
                     /locus_tag="ctg1_1273"
                     /protein_end="364"
                     /protein_start="52"
                     /score="187.5"
                     /tool="antismash"
                     /translation="IQNQWGKKKKNTYEVAVVFNKEHGKLNDADKAAINNTVSYLENHK
                     KKYGITDVLAPDSNIATRKKLQSKDGTTWVMQLNISKKHGRIGEVEDQITKAVKTQGVR
                     TYVTGADILQNAFSTSIQEGIKKTEAITVVFIFIVLIIVFRSPIVPLISLLTVGVSFLT
                     SFSIVTNLVEHANFPFSNFTQVFMVIVLFGIGTDYNILLYDKFKEDLGKGMDKYEALRD
                     SLRNAGKTILYSGSSILIGFTALSLAKFSIYQSAVGVAVGVATLLVVLLTLNPFFMAVL
                     GKNMFWPVKEFTGESENKLWHGISAETLKYP"
     CDS             complement(20024..20587)
                     /locus_tag="ctg1_1274"
                     /transl_table=11
                     /translation="MTQKRSLDLNKIIDKAIQLIRDKGLTETTLPALAKELGVRSQSLY
                     HYVSNRKQLISLVGASRIKVLHQKLIENLMGVSGKEALLKFADVTRDFVLKDPALSSIL
                     YHLNEYSEDDAINREILNIIQLGEKLNLKTTSTISAHALIGAVLGYVFLDKSSSFPDES
                     EDEANRNYHEMILRLVQPIAVLQE"
     PFAM_domain     complement(20423..20554)
                     /aSDomain="TetR_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00440.25"
                     /description="Bacterial regulatory proteins, tetR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1274_0049"
                     /evalue="4.40E-09"
                     /label="ctg1_1274"
                     /locus_tag="ctg1_1274"
                     /protein_end="55"
                     /protein_start="11"
                     /score="36.1"
                     /tool="antismash"
                     /translation="IIDKAIQLIRDKGLTETTLPALAKELGVRSQSLYHYVSNRKQLI"
     CDS             complement(20689..21627)
                     /locus_tag="ctg1_1275"
                     /transl_table=11
                     /translation="MKNKVFIVSLIATIISFSLYFANLKRVKNASINIIEPKTSKTSPK
                     KKVKEPKPKIKEPKIKTIEYANHVKVASGSQKKLAQKIKQIMGKDYSYQVAVQDLNNSA
                     KFCRVANTKVAHNVDDTMKLYLLLAIYEQEQQGKLTSKTVIKIKKSDRVNGEKALKTNM
                     SYGISFLRQAMMRGNKTAANALIRKVGHDKIDAIIKKLGADQTTMSANFSKAPYGKTTA
                     HDLVKTMAGIYQGRILNQKHASLLLQALNSKPNFVKGINGGVYAIGDDHSAVAIVQTQG
                     HSYCMSVWSSNNKKFNELGKAINASFTAKKK"
     PFAM_domain     complement(20869..21297)
                     /aSDomain="Beta-lactamase2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13354.8"
                     /description="Beta-lactamase enzyme family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1275_0050"
                     /evalue="1.20E-21"
                     /label="ctg1_1275"
                     /locus_tag="ctg1_1275"
                     /protein_end="253"
                     /protein_start="110"
                     /score="77.3"
                     /tool="antismash"
                     /translation="NTKVAHNVDDTMKLYLLLAIYEQEQQGKLTSKTVIKIKKSDRVNG
                     EKALKTNMSYGISFLRQAMMRGNKTAANALIRKVGHDKIDAIIKKLGADQTTMSANFSK
                     APYGKTTAHDLVKTMAGIYQGRILNQKHASLLLQALNSK"
ORIGIN
        1 atggaacttc cgcagttgga ataagcgtca agtcacgtgg cttgtctgga tcatcgttat
       61 ctacaatagt gtatacgtct tcgcggaatt tagggaattg gcccgttcct tgcattgaag
      121 cgtcatttac aaggtaaggt ggaataattt ctgtatatcc ttctttggtg ttttcatcta
      181 agaagaagtt aaatacggcg cgttctaaaa gcgcaccagc tcccttatag taaacaaaac
      241 gagcaccaga aactttagca ccgcggtccc aatcaagaat atctaaatca gtaccaagat
      301 cccagtgagc ttttggtttg aaatcaaatt tagtaggttc ttcccactta cgaacttctt
      361 cgttatagct ttcatcagga ccaattggat cagaatcagc tgggaagttt ggtaaacgaa
      421 gcaagatata ttcttgcttt tcagataaat ctctaatttc attatcgaga tctttaatct
      481 tgttacttac ttctttcatt gatttaatgg catcgctagc gtcttcttta ttacgcttag
      541 cttcaccaat cttctttgag acattgttac gttctgcctt taattgttca ctttcattta
      601 aagcttcacg acgtctagca tcaatttgaa ttagttcatc caattcttct ggcttaattc
      661 cacgagttgc aagcttatct ttagcccaat caagattctc acgaattact tttatatcta
      721 gcatttataa aaacctccat aaaaaagagc cgtccatccc taaattggga cgaatcggct
      781 ctgtcacgac ttcgcggtac cacccatctt cagcctaaac ggctgcactt cattataagg
      841 cgaataacgg cgccaagccg tgcaactatt aattgcccac atttagaaat ctggaaacga
      901 catccgttcg ctcccaccaa ccgcgaactc tctgaagtag tcttaggatt tcgtgttttg
      961 ttctatttta agccattctg tttttttgag caaatagtat ttttccttat acgaaaaaag
     1021 atcgctaatt tggctatagt cgatttcata aatatattta aagcctaact ttttcaataa
     1081 attttgcgat ttgagattat tttcaaaagt tccggcccat atttcatttt gatctaaatt
     1141 aataaaagca tctttaacta ctaaatcaat agcttcggtc atcaaacctt tttgccggta
     1201 atctttatcc attaaaaagc ctaattcctt agtcttaagc agcccgcttc tttcatccat
     1261 ccctcgttca tttaattcga ttaagccgac aacctgatca ttttctttta aacaaatcaa
     1321 ataactattt ttacgcatga tatattgctt ggctgctttt ttggcctcag ctaaattctc
     1381 atagctacca aaaccagcac tatcatgata acttttgtct ttaccccatt ttaataaaat
     1441 tggagcatca ttttcagata catttcgtaa ataaattcgt tttgatgcta acattactta
     1501 ccaactaact ttaggagcca atttgctcca tatactaatc cgatactgta ggccgcaatc
     1561 gtccatggct tacacaaaat aataatccaa aaatacgtcc agaacttcat ttctgttagc
     1621 cccgctaata aacatagaac gtcatctgga gcagcaggtg ccaaaataca aagagcaaaa
     1681 aaccagttga atttcttttg atttttcgtc cacttcatgt atttattcaa agtttcttct
     1741 gaaacaatat gaaagataaa agatcgccca tagtatcttg ctaagaagaa gttaattatt
     1801 gatccaatac aaattcccac ataattatag aggaatccag caacgggacc aaagaaaacc
     1861 actcctccta aaagagaaac tcctcctgga ataatcggaa ttactacttg gacaatctga
     1921 atcaaaacaa agacaattgg tccaattatt tgcttatttt gcaaatatgc cttcattttt
     1981 tcttgattgg taaaaatccc taaccgatac caataaatca ccaacaatat aattatgatt
     2041 ccacaaatga tagtggcata attaattagc tttcgactag ttttagctga caagtgcatt
     2101 taaatcatcc cctaacttaa attaattcta tcaaaatact ggtgctgcac cctaaatctt
     2161 aaatatattt aattatgttt atcgaaaagt caatttttag ttaaatcaat actttataat
     2221 atataatata agcgacatat gagtttttta aaaaggatgt gtttataaat ggttgtaata
     2281 aaaaacgaca ttacttacga ttcagaaaag aaacttaaga cagacatcta ctatcctaat
     2341 gatacgactt cagcaacaaa gattttaatc ttttggcatg gtggcggttg gttccgcgga
     2401 agcaaagacg atgccaaaaa agttggagtt aacctggcta atgctggttt tatgaccttt
     2461 attccagatt atagtcttgc tcctgagcat gtttttcctg aagcccatga tgacgcagtc
     2521 catttcgtga agtggctttt aaattcaaac tatactgata aagatgatca aaaaaacatt
     2581 gttcaaatcg gagccagtgt tggaggaacg ctcgcacttt atgtagcggg gaaatatggc
     2641 tttcctaccg tcacttggtc agcgccagtt gaattttcaa aatggatgaa aaaccacgaa
     2701 aatgttaaac cttcatatga aggggctaaa gagtttggtt taacagattt gcatgacata
     2761 aataattcgt tctataaata tttcactcta acttatgcag gaactgctga tcaaaaagtc
     2821 cttaaaaagt tagatgcaga ctcttatgat tatagtcatt taaaagaact catgatgatt
     2881 aattcggctg atgaattgaa tcctttacct aacgttctta atttcattca atttttagct
     2941 gatcaaaatt taggtgttga attactcgtc atcaagggac atcgtcacgc tatggcatat
     3001 gcgagcgatt atattgatga atctcttgat tttttgtatc aaacaattaa gcggcagaaa
     3061 taattatgat taacattgat aaatttataa aaataagaaa atcaaagaaa atttcacaaa
     3121 atgaactgtc tcatggaatt tgtacacaat ccactttaag taaattcgaa aacaatggtc
     3181 aagtaccttc ttttaagata ttaaagcaat tgtgtgatcg aatggggatt gaagttggcg
     3241 atattattag acaaagtagt gataatcccg caacaaaaaa catgtttgaa gcagaatttg
     3301 cattcattac ttatgattat aataagatcc gtgacttact ttctagcatt cacgaacaag
     3361 atttaaagca cgaacaagat cgccttcatt ttgattattt gcgcgggctt tatgcgctgg
     3421 acggcgaaaa aaacgacatg actgcacttt attatttcaa caatatcctt tccaaccgtg
     3481 atattgccga taataatatt tatcgattgc ttgctttaaa tggatgtagt caaatttatg
     3541 ccagtgaaaa tgatatggca aaggcccatc attattatga tcagattttg agctacatta
     3601 aagatattga cattgatgat gaattaactg ctttacaagt tttggctatc ttatgtgatg
     3661 ctggtgaatt tttcggcaaa caaaaagaat ataagaagtc taactctctt ttacgttacg
     3721 cttattcaat tgcctctgag aagcatacag tttacttctt agcgcgtatt ttatttcgct
     3781 ggggactaaa tgatattgag caaggtaaag gcctagataa ggccttacag cacctctatg
     3841 atgcctgtgc atttgcccgc ttgaataaga atcatgtcat tttaactaag gcgaaaaaat
     3901 taattaaaga actcaatcaa aaaaacgtgg attaattcca cgttttttct ttagataatt
     3961 ttgtatccca caactggatc agctgggcaa gaattgaaat catagcttgc taatttttca
     4021 aaactgtcat ttccatcaat gatagttgtt acaccttgtg caagcattaa attcatttct
     4081 ttttctttat tttcaatttc agtaaatgga actaagataa ctggcttgtg aagtgcacgg
     4141 aaaaagccaa tttcaaaggc acttccgtca tcaatattgt ccatgtcata caagaaaaca
     4201 ccacaagtag cattcacaat cccatttaaa tcattttggt aagttgcaac acgccacgtc
     4261 atgctgcgaa caccgccaat ttcagggttc ttttcttctg gatctacgaa attttggtca
     4321 aatgggaaat gcacttgcca aactgtagga ttttgagcaa gcaactttct tgctttagta
     4381 acgcgttctc tttgagcatc attgtaaaat ggtgatccta aataaatctt tgcggtggaa
     4441 atttctgccg tcataattta ctggtatata aaacatagaa atatgtagaa gaatgcgaat
     4501 tttctacata tcagaaagat atatttttcc tttctttgtt tcacttactg tcgtcttcac
     4561 tagtattccg atattccaat ataggagtaa tcacattgac tagctcttcc agcttaaggg
     4621 cctagccagc cccgtttatt ttctttaatt tgctaaagct aaaagattta atactgcatt
     4681 ttcatctcga tcgttactgt agccacattc ataacagata tactcattat gctttgtgcc
     4741 atgctttttg ttgccttgca aagtgatctt ctcgtcacct tttttaacat agccgcactg
     4801 agcacatctt tgagttgatg ggtaggtttt ctcggccaag atcagttctt tgccatacca
     4861 atcgcatttg taagttaata tctgtctgaa tttaccaaag agcgatctct gcataccttt
     4921 ggaagcgaca tgcgtcatca tcatttgctt tattgctaag tcttcaatta caatttggtc
     4981 gtaatcatta acaagcttag tagtaaactt ctgtaaaaga tcgttttgga tattggctac
     5041 tctgcgataa tttctctgca atttggttct cactgcaaag taattattgg atttagcagc
     5101 caacttaccg ttaacctttc ttttacgagc tagcattctt tgataatgtt taatccgctt
     5161 atacagcttt tgcaatttag caggcaaaac aatgatttgc ccctcggtat agttgaaatg
     5221 accaacattg acatcaattg ccgttttatt atgagtttta gttttagcta gtatatcttc
     5281 ttcataaggc aaagatgcgt aataactatc tttttctttg aagatgctta ctaccttaac
     5341 ttcatccatc tttaagactt cataacttgc tagatcaaac caactatctc ttgaaatgct
     5401 tcttggacga tcaaggcgga gcttcccgtt cacaatctta gctctgtcag ttttaaagcc
     5461 ttgcctaggt gccttcttag atctaaatct aggcttgccc caatcaggct gagctttatc
     5521 aaagaaattc ttccaagcat tagccaagtc tttaacagct aattgtaagc atcgagctga
     5581 caaattatat tgccagtcgg ctttattagc cactaattca tcgcggactc tgcgttcgtt
     5641 aggattggga ttatcttttt tgtttaatgt atgagcttca tacattaact gccaagtttc
     5701 taagccttta ttccagcagt atcgacgata atcgcacaaa gtatcaagat gcttttgcat
     5761 ggtcttatta acttttagct ttactacttg tgttttaatc attgcttcac ctccttaaat
     5821 acaaacataa gtttatctaa agagataaag caaaacaagt aaaaatttaa ttaaagctta
     5881 ttttccatgt ttaactttct aaataagctc tatcttttgt tttatctaca aatttctata
     5941 tttttccata tttttgttaa cagttaatca gctcctttag aattaaaaat atttattccc
     6001 attctaccat gaccgggatg caattttagt caaaattctg gaagttaaat ctgaaaacgc
     6061 ttagaattaa agtgtattaa tttgaaaaga aggtttgaca atgtctagat atcaatcaat
     6121 aaatccatat aacggagatg tctttgccac ttttgaaaat ccaactgaca aagaaatcga
     6181 agaatcactt aacttagctc atatgcttta taaaaaatgg cgtcatgaag atccaagcac
     6241 tcgtagcaaa gaattgcttg ctattgcggg aggttttcgt gaaaacgaag acaaaatggc
     6301 ccaaatgatg accttagaaa taggtaaact tttcagcgaa gccaaagaag aagttgagct
     6361 ttgtattcaa atttgtgaat attacgctgt caatggtgca gatatgttaa aaccacaacc
     6421 tcttgaatca ggtttaggaa atgcttacta cttaaagcaa ccaactgggg tagttttagc
     6481 atgtgaacct tggaactttc cactttatca agttatccgc gtcttcgccc ctaacttcat
     6541 ggtaggtaac ccaatcattt tgaagcatgc tcacaatgtt ccatcttcag ctgctttaat
     6601 ggctaaaatt attaaaagag ctggtgctcc agaaggcagc ttaatcaatc tttatttaag
     6661 ttatgatcaa ttagcacaag ttattcgtga ccctagaatt caaggcgtag ctttaactgg
     6721 ttctgaacgc ggcggcagca gtgttgctga agaagctggt aagaacttaa agaaatcaac
     6781 catggaactc ggtggaaacg atccatttat tgtattagag gacgctgata aggatgtttt
     6841 acgcaatgtt ttgtctgacg cgagaactta caatgatggt caagtctgca cctcatctaa
     6901 gagaatcatt gttgttaagt cccgttacga agaagtctta cgagaattaa agagtttata
     6961 tgaagtatta aaaccaggcg acccacttga ttcatcaact actcttgctc caatgaattc
     7021 tgaaggtgct aaagaaaaac tagaaaagca agttcaagaa gcagttgatc atggtgcaca
     7081 aatttactac caacacccag aaatcgaatc aactggtgcc ttcttcccac caacaatcct
     7141 tacccacatt ggtaaggaca atcctgtctt tgacaaagaa ttgttcggcc cagtagctga
     7201 agttcactgc gtagaagatg aagatgaagc tattaaatta gctaatgatt caagctatgg
     7261 ccttggctct tcaatcatca gcaagaatac tgctcatgca gaaaagttag ctgctaagat
     7321 tgaaactggc atgactgtaa ttaatggccg ctgggtaact gctcctgaat taccatttgg
     7381 cggagttaag aagtctggct atggccgtga attaggcaaa cttggcttga tggcctttgt
     7441 caatgaacac ttggtaattg acactacttc agaaaacgaa taattaaata atttataaaa
     7501 aaacaaaaag acaaccttca cgtgaagttg tctttttgtt tatcaaaatt tatttttgaa
     7561 tagtttatgc attttgtgag tattccgcac agaatagtac tgtgactccc cattaacaaa
     7621 accaatcttc ttttctctaa agtttactct atctacattc tctggattaa ttacacaaga
     7681 ctgacttatt tgaacgagac ttccatattt ttctggaatt tcttttaggt ttccaataaa
     7741 atatccccac cccgttgttt ttatcaactt taatttatgc cctacagaag ttgtagttat
     7801 ataaattaca tcacctaaat taatatttct tacttcttga ccaaacttat aagaaaaagt
     7861 atttttctta ataaaatctg cattagaaat agctttagtt gcactttgta aagcataatt
     7921 tacatctttt tgtagatcac ctacattacc atttttaata ataaaatcta cagcacctaa
     7981 ttttctctta aaggttaaaa atgccatatc ttgatgactc gttataaaaa tcaattgagc
     8041 atttttgtct ctttttttaa taatctctgc taaatcgaga ccattttttt cgtaaagttt
     8101 ctttccgatt tcaatatcta aaaagtaaat tccagactta aaagatactt tttcaataaa
     8161 atttatagca tcatcgtagt tatttacagt tttaacaata tcaaattcca acttatcttc
     8221 atcacttaaa ataatgctag attttcgaat acattcttta aggatattta cttgttcttg
     8281 ctcgtcatcg catataaaaa ctgaatattt tatttttcta tcctccctta aactaattag
     8341 ttggcaaaag aactaaactg aatgtaaacc attctccttt agtatctaca tcaaccataa
     8401 tattttcaaa gtacttattg gcaatttcca tggcattact taagccaagc ccgttatggt
     8461 cgttcttagt agtaaatcct gcttttagaa tttggtcctt atccacttga tcgattttat
     8521 ttctaattat gaattctaaa tttccttcac tttgataaag catagcttca atttgtgcat
     8581 tttttaatcc ttcactagct tctatggcat tatcaaatgc gattccaatg attctcacaa
     8641 tatcaagctc ttcatcctta gaaataaaag gaaagtcaat tatatccttt tcacagctaa
     8701 atctataagg aattttatca tcatatattt tagctaattt ggtgataata atgcttttaa
     8761 tcatgtcgtt atgaatatga tgtacgtctt taaacttaga taatgtattc tcatcaaaat
     8821 gattttgact atactcatcc aattgtttta tcagtgcttt agaatcgtct ttctgggcag
     8881 caatttttaa accattcaaa atattgcggt aatcatgctt aaatctacgc aaacgatctt
     8941 catctttttc aagagaggtc gcataatcct ttaattgttt attattcttt tctaattgat
     9001 gatttacgtc ttttagtttt tgctgctctg ctttttcaag caaagtagtt tgaagttgga
     9061 gattcagttt taagctaaca atagcataaa ctccttgaat cactagtatt cccaaaatag
     9121 tcagggtttc aatagtaact tgcttttcca aagtagcaac aatataagct atggcagtcg
     9181 aaatgtatag ataaagcaaa gtgtaaaaaa ttgttttctt atttataccg gagaatagcc
     9241 tatttaattt tgaagaataa tgcctaataa ctatatattc tataatgggc aacagcatag
     9301 acatgaattc cactagagca gtattggtaa atgataaatt ttcacttatc gttataacaa
     9361 aatctgaaat taaacttagc atggctacta ttattccagc attaactagc aatattttat
     9421 ctttcactcg tttataaaaa actatttcaa acaaactagc ttctatgata gtaaaaataa
     9481 gatctgtttg atccaatttg ataaaatctg aaattgattc taataagatt actgtaatgc
     9541 ccaatccaat taagacaaat ctatcaaaaa tactttttac tcttagttta gttatattta
     9601 gaaaaattaa tatatctacc gcagggccta taaaaaatat attaataatt gcaagtaaca
     9661 ttatttaaac aatcttttta aaaattgcat tactttatgt ttttcggccg tttttttact
     9721 aaaaaaacta acatacggat taaaaaggcc atttacttca attaatttaa tttttttcat
     9781 cgatttttcc tttcctatac accaaaaagc gcaaccctag ttacgctttt tttgattatc
     9841 tctttcatct acttcaaatg aaagattgtc ttgatatgat tccaacaaaa cagagagaaa
     9901 ttataatttt tagttccacc atgaccacga cgtcttgcta gactaacaaa aggtgtggtt
     9961 ccttgtaagt tgaggatatc ttgattttca tcatgcatcc ctattcacct cctttcagta
    10021 tagataattt agcactatga ataatgggta accactgccc ccaatcatta tctattattc
    10081 cttgtaaagt cagtaaaact ccaattgcac ctgaatctaa atccattgaa ttctttaacc
    10141 catgtcgtcc tggaaccaga atttcatctt ttttaattac taaataatta ttcagaagat
    10201 gaatcttttt ctgtaacgca ttcgaatagt cataattctc agctgctaaa tctgccagca
    10261 ttaatccaca aaagccatca aatattccat tcatataagt taatttaaca tcattagtag
    10321 ctgacaatga ttcaattagt tttcttccgt cttcaatatt tatcccatcc ttaatgaatt
    10381 ctaaaataac aatttctagt cctgctgaac cagaatttag atagggtaaa taattagagt
    10441 gcgtttcatc cattaaatat aaacctcgtt cggttctatg cagctcgttt ttgataaaaa
    10501 agtttacttt actttctaca cttttaaata agatagaatc ttgcaaatag atggccacct
    10561 tttctaagaa aagcaataat cctaatttac catctaacaa tcctgctgaa ggacactcat
    10621 catagttatc atttacattc ctagctatct cttttatttt acgttgtcga gcaaattcag
    10681 gttctacttg atttaaggct aatagtgcta acccaatccc tgctaatcca tctttcaatg
    10741 ataaactcga aatttgggaa taatcaattt gatcgattat tttttttcca agatctttat
    10801 taatattaga atatattacc gaacctattc cagcagctcc agtgaataat cctgaatctt
    10861 tctggatgcc cttccatatc tcagctttat tttgttcaaa ccaatccaaa aattgagtcc
    10921 gcgtcccttc attcaaatcc gaaagaataa gacctaatcc cattccacca ttcagaatgt
    10981 taaacatccc tatggtagat aaatactgtg atatatcccc ttttaaaatt ctttcttgat
    11041 taaaatcgag attattttta ataccttgtc ttattttttt aactgcctct tctaaattat
    11101 taagatcaag tgaaaaataa gctttttgat ttaatgaata gctttctaag ctaatctttt
    11161 catagcattc tttcttaaat gacatcaaaa atttatagac tgctgggtca tacttcttca
    11221 aattctgatc ttgataactc tcgctagtat tatcagacaa ctcatcaata ttgattattg
    11281 gcaaaaaggc atgcctaatt gtcttgtata ccgcaatcca atcagcttct ccatacgttt
    11341 gaacatcaag atctacaaac ccagtagttt ttaatcccgg attatacttt tcggttttgt
    11401 tatttgcttg ttcaaagtca atcaaaatta catttttatt ttcattaatt aaaatattat
    11461 ctggttgtaa atcaccaact gctatccctc ggctatgcac atctttaatc gctttaatta
    11521 aattatgggc tatctctttg attatattta aatactcaga gttttctcca tgaaatggaa
    11581 aattatccgt aatataatct cccaaatttt catatggtaa atactcttca accaaataat
    11641 tatgaatcca tacaggaaag tattctttaa agttaactac atagggtgaa ttctgcagtt
    11701 ttttaagtat atcagattca tgcttaattc tagaaaatcc gtcttcgtaa ttagaatcaa
    11761 tcccggcctg taatcgacct tcttttaaaa cataattttt attttgaaat tctcctacat
    11821 atactcctcc agcattactg aattgcaatg ctcctgtaat gtggtattta tccaattttt
    11881 ctttattagc aattcgtagc tgtgaaatat cttgctcatc cattaatgga tcttctacaa
    11941 aattgggttg ttgataaaaa ggttgccttg aatctgggat tagatttcca ttctcatccc
    12001 gaatacatag aattccttga tcgtttcgta attctgtaaa agcaccatat cgataataaa
    12061 tattggtatt tttatatctt ttatctgaca aaatatatgg tccaatttca aaagaagcaa
    12121 ttttcttaga cacatcatga actatctctt taaattcttg atcattttgc ggataaatcg
    12181 taataaattt tcctgaagaa actctatcag ctgattttga attctttaaa atccattctt
    12241 ctttaccaat cgtgacttta aaagttactc ctttatcaac taaatattta gttacagttt
    12301 gaagtagctg ttctatatct ttatatccag ctgaaagatg aattttccat ccttggtctg
    12361 gaagctttgc tttagaattt aaaaaatact gccaatgtaa atcagaaaat tgccgccaac
    12421 cttgtggaac tttcacctta aattcattag cctttttatt aggttcgcta aaaaaatctt
    12481 tatcattaag tgtaaaagga aggtaacctt ctatattgta tttcatatta ttcctcgtta
    12541 gatatgaatt gatcatttac aaattcctta tatttaggaa tttgatgtaa tagatctgaa
    12601 tgctttccaa ctcctaaaat tgtatgatta tccataaagt aaatcttatc tgcattcaca
    12661 attgtcgata atcgatgtgc aatcacaatc aaagtctttt tctccgacaa tttgtcgatt
    12721 gcctttaaaa tttctgcttc tgattccgga tctaaatttg aagtagcttc atcaaaaata
    12781 ataaaaggag tattcctcaa ataagcgcgc gcaatttgaa ttttttgtcg ttgtcctcca
    12841 gataactttt taccattttc tccaacttca aaatccaatc catttgataa ttgactaata
    12901 aacttttcca atcttgccag cttgatcgct tcagctaatt gcatttgcga tggatcatag
    12961 cctaacccca aagttaaatt atccttgata gtccctgaaa agacgctatt atcttgggtt
    13021 actacactaa ataaagaacg ccatgccttt aaagaaaaaa tttgagcatc aattttattc
    13081 cataaaactt caccgtcaaa agtattttga agtctagtca aaatactagt taaggtagtt
    13141 tttccggctc cagaaggtcc cactatagca atttttttgg ctggctcaaa taaaacattt
    13201 acatctttta gtactttgat aggtgaatca gtataattaa aaaatatatg tttcatcttt
    13261 aaatcagcca catgaggatg ctcaatattt ctaccttgaa gacgctcctc tttttcttcc
    13321 ataatcttat taatgacctg ggaagcacct ttcgcctcag aatagctcac ataaaaatta
    13381 gccaaattat taataggagt aataatttca aacacgtaca tcataaagga cgctaaaatt
    13441 cccatagaca atgtgtgatg agctacacgt gaacttccgt aaagaataat taccaaaaat
    13501 gctaaaaggg taaacgaggt ttgaataggc cctgtaatac taaaaatctt atctactttc
    13561 ttagataagg agtaaacttt atcattttgc tttttaaaat tattctctac ttcagtttga
    13621 gcattatata gtttaatgat cttaatattt tggatatttt cagttataac ttgagataat
    13681 ttactcaaat atttttgaat agagaaagaa tatttttcat taactttccc taaaggataa
    13741 gcaataagtg atactaatgt aaacgaaata ataattacaa aagtaagacg aacgtctaat
    13801 attagtaaga tcagtacgct tccacataga gtaactatac taataattgc actgggcaat
    13861 tcatttgtag taaattcttt gataatcaaa gaatcattga tcactcggct tactaattca
    13921 ccgcttgaaa ctttttcata aaatgaaatt ggtaaattta ataatttctt ttctagtttc
    13981 gcccttatat ttcttatcct tttatctccg gaataactaa ttaaataaga gctaacagca
    14041 ttaatgatag atcctccaat taataagagt attattggca ataaagtgga aattgaaaat
    14101 ttgacttttg accctagatc aataaactgc tgaacaaaaa gtggcaaaat taaattaaat
    14161 aagcttccaa taacacttag cagaatagct attattaata atctatctac ggcgaataaa
    14221 ctaatttgat tttctttctt cataattagg cgaatagaat aggtggtaaa tagatatttc
    14281 tcattttatg ttttccatgt ttattaaaac agaacacact aattctttta cttgttaata
    14341 aagcttgaga agaagttcca ttcacattca atttttgtaa atttaatata ttagaatttt
    14401 ccattttttc ttcctctaaa aaatattcca gcaaattatt gttactcgag ttcttgaagt
    14461 tctatgcttt ctacgctttt ttacaaaata ttctacagtt gcttgcgtag ggtaagcctg
    14521 catatttata attgaattca ttttctcttc ctttttctaa aatttaaacc aatctgaaaa
    14581 atcatgaaag caaatcaaac tatgtttaac ttcattgtta ccatcacttt gcttatgatg
    14641 tttcttttcc tctctttgtt tttgcaatcc taaaattgcg tttataatgt tttccatttt
    14701 cgatctcctt ctcatttgac tttatcttga cgatttcata ttatcactgg cttaacttaa
    14761 tttacggaaa taacataaat ggttaaaaat ctaacaaatt tgtcgaattc taactcaact
    14821 tttatatcac tgatcaaaaa acaagcaatg aaccttctaa aataaagaag atttattgct
    14881 tgcttcaact accttttctt aaaataatta tacccagcaa ggcccgtcgt caataaactc
    14941 gctaaaatca agaaatatgc cgatgagcca attgagactg catacatcaa aaattgatta
    15001 gttaattcgc caattacacc atgatttgat gaattattgg aaatcttaaa gacaatataa
    15061 atcaaaaatg cagtttcaag cagcgacaaa ataaaggcaa agaattgact atttttcgtg
    15121 tttttgaaaa tattgtaaat aataaaaatt gggaaaagaa ccagtagtag ccaaaataca
    15181 tacaaaataa ttgctgacat agaagtatga ctagaggaaa gtagacgatt tgccaaattg
    15241 agaattactt tggaaagaga aagtttttga gtataactta catctgccac agctgctcct
    15301 gaacctgtaa atagcacaat taagctgatt acagaagtta aaactacaga aagttgaatg
    15361 tagctaaatt ttgacttgct acgctctttt actttttcaa catgccgatt aacgtgggga
    15421 tgggtttcag tgaaattctt tccctttttt cttactttat ccgtgtgctc tttagcagta
    15481 ttgaccacat ctgaacccat tttattaatc atttcagtta gccgtttatc agctgtatat
    15541 tgctcaattt tatctgcttt atcacaaaca ataaagagcc acaccatcaa aactaaaaac
    15601 gatgtccaac ctaaggctcg tgaaaagctc atgattacta aaagaactac tcctagtaag
    15661 aaaacaattg tcgcattact tctcacccaa gcaatcatct tttgaatagt cgtattttgt
    15721 tttttcggtc gaaattcttc gcgatattgt gcacgtttag gctgagatga gacactcttt
    15781 ttttcagagt catcttcaaa aaaggtatca cgatactttt ttaaattaaa accacacttt
    15841 gggcaaatat catcatcttt ggtaacggat tggccacaat ttggacatgt agtcatagta
    15901 atcctccctt ctcaaaatca atttacctaa attatatcat tttcattctt aaggtgttag
    15961 aagccatatt tccccttctc agcctttttt attttagaaa taaaattatc gttttcacat
    16021 ctcttgtcct cattatgcgc cactttttat tatttaagca aaaaaataga gcaggtctca
    16081 gacctactct attaatttat tttatttagt catcgaatgc ttgtgttttc ctaacttaaa
    16141 tccggaaaat ccttcataag tcaatttcac accagctgac attgtaattg gcatgataaa
    16201 tactaaaata atcaaaccaa caataactgt caatgcaact tcaattaaag ttggaatacc
    16261 tgatgggata agagcagcaa aagtaccacc taaaataacc gctgcagaaa ttactactgt
    16321 accgataata ccacaagcct taaggattct agcacttggg ctagtcagac cctcagtttc
    16381 cagctcacga tatctcgtca taaggaagat actatagtct acacctaaag caatcaacat
    16441 aataaagctg aagaatggtg tgttccaagt aagaagatct cttccaagaa caagcttaac
    16501 aatccattga ttgattgaaa gtgagcagag gtatgcaata agcaaagtac ccaagatata
    16561 tacaggttga agtaatgaac gagttacgaa cattaaggca ataccaatac caatcaacat
    16621 aattgcagca gttctgataa agtcaccact tgcaacattc ttggtatctt cgatcttaga
    16681 actttgtcca cccattgcaa ccgtagcatt cttgagttta gtaccttgta atgacttctt
    16741 agccattgca ctaagttctt gtgaacgagc cgtagcttca ggagcacttg ggtttgaatt
    16801 gaagacaaca attaacattg ctgacttctt atttggactc aagtaaacat caattgactt
    16861 ttggaacatt gcgttattaa tgaattcctt agggatgtag aacgtatctg ctgcagcaga
    16921 tgagccgaga cctcttaagt aagcttctcc ttgacctaaa ccactgttaa cacgatcaat
    16981 tcctgaggta agttgtggcg tactgtcagc taaacgtcct gcacctctac tcaattgact
    17041 tgcaccgctg ttaagttgac cgataccgtt actcaactgc tcagcaccac ttgcaccttg
    17101 tgcaagacct gagtttagtt gaccggcacc tgaacttaaa ctgccaagac cgctgtaaag
    17161 ttgacctgcg cctgagttta aacgacttgc acctgagctc aaactaccaa ggccgttgta
    17221 aagttgacct gcgcctgagt ttagacgatt tgcacctgaa cttaaactgc caagccctgt
    17281 attaagtgta ccgatacctg aatttaattg agcagcgcct gagttcaaac gacttgcacc
    17341 taaactcaaa ctacccagac cgttgtaaag ctgacctgcg cctgagttca atgaagcaac
    17401 tccactgttc aaacggtttg caccagcaac accttgagtc acagcacctt gaacttgtga
    17461 taaaccagaa ttcaattggt taagggcagt tactgcacct ggaattgctt gattagaagc
    17521 agcagctaaa gcattaactt gtgtcttcaa agcttgaatt tgattcaaag tattactttg
    17581 ttgcattgct tgcatagaac tttgaagtcc ttgagctgca gaatttgctt cagcaagagt
    17641 actttgaagt tcaccacttg aagatgaacc actattacca ctaagagctt gttttactgc
    17701 cgagcttgct gcactagcac cagcttgagc agcagcggcc ttttcttcat cagttgcttt
    17761 agagttactc aaagctcctt caacagcttt ttgaacagcg ccagaaattg cactttcagc
    17821 agcagaagca ttagtgttag aagaactacc agcactaccg gctaagcttt gcaacttact
    17881 taaactactt tgaagtctag cagcatccct ttgaacactt gctaaaccat tagtagttgc
    17941 acttgtatca actgcaccat ttaaagcagt attcaaagct tgaataccat tattaatttg
    18001 tggaagtgca gattgtaatt gtgcaagttg agcacgattt gagccattca attgggttga
    18061 caattgatta tttaattgat tcaagccatt tactaattct tgcgtaccat tttgtaaact
    18121 ttgggtacca tttcttaaat taccagcacc attttgcaaa cgggcagctc cgctttgaag
    18181 gctacttgca ccgttttgaa gagctaaagt accactagct aatctaccag caccagcttg
    18241 aagacgacca acaccgctca caagagaact agtaccattc tgtaagctgc ttgctccact
    18301 ttgtaaacga tcagctccgt tttgcaagct ttgagtacca ttttgcaaag taccagctcc
    18361 gttttgtaaa cgatctgctc cactttgtag acggcttgca ccattttgca aacgagtagt
    18421 tccgcttcta agttggtctg ctccactttg tagacgaccg gtaccatttt ctaattgttc
    18481 ggccccactt tgcagacggc ttgcaccatt acttaatttc tggctaccct tactcaattt
    18541 accaagtcca gaacgagctt ggtcaacacc ttcatttaca gtgcccaatt gattatttac
    18601 ataaagttga tcaattggtt caccataagg ttgagttaca gaagtcacaa atgaaacatc
    18661 ctttgaagct tgaagctgtt tagtcagttg atcaatcaac ttcaaattag cttcattatc
    18721 taaacgatgg tcactcttaa tatataagta tgaaggttca gccatccctt tagagaagtg
    18781 tttttgtact actaaaaggc cggccttcgc tggtacatta tccgcaattt catcagtatc
    18841 atcataattt agttgaccat gatacatcaa cataaacgga atagttacca cagctaaaac
    18901 taccaaatag atgaccggat atttcaaagt ttcagctgaa atcccatgcc aaagtttatt
    18961 ttcgctttca ccagtaaatt ctttaaccgg ccaaaacata tttttaccaa gaacagccat
    19021 aaagaatgga tttaaagtca agagaacaac taataaagtt gcaaccccaa cagcaactcc
    19081 gactgctgat tgataaatag agaatttagc taaacttaat gctgtaaatc caattaaaat
    19141 tgatgaacct gagtaaagaa tggttttacc ggcattgcgg agggaatccc taagtgcctc
    19201 atatttatcc attcctttac ccagatcttc tttaaattta tcatacagca aaatgttata
    19261 gtcggtacca atcccaaaca atacgataac cataaacact tgtgtaaagt tagaaaatgg
    19321 gaaattcgca tgttctacca aattggtaac gattgagaaa gatgttaaga atgacacacc
    19381 aaccgttaac aatgaaatta atggcacaat tggtgatctg aacacaataa taagtacgat
    19441 aaagataaat actactgtga tagcttctgt cttcttaata ccttcttgaa ttgaagttga
    19501 gaatgcattt tgtaaaatat ctgcacctgt tacgtaggta cgaactccct gcgttttaac
    19561 agctttagtg atttgatctt ctacttcacc gattcgacca tgctttttag aaatattaag
    19621 ttgcattacc caagtagtgc catcttttga ttgcaacttc tttcgtgtag caatgttaga
    19681 atcaggagct aaaacgtccg taattccata tttcttttta tggttttcta aataactgac
    19741 agtattatta atcgcagctt tgtcagcatc gtttaatttg ccatgttcct tattgaaaac
    19801 aaccgcaact tcataggtat tctttttctt ctttccccat tgattttgga ttgtttgtgc
    19861 aacttcgctt tgaacattgc ttggtaatga aatcgttgaa tgttcactag tcaattgact
    19921 aacatttggc aaagcgaaga cggaaattag caaaattaaa atccatgcaa ttaatgaaaa
    19981 cacatggttt ttcagaaatt tctgcaattt tcctttcccc ctattattcc tgcaaaacgg
    20041 caattggttg tactagtcgc aatatcattt catgataatt acgattggcc tcatcttcac
    20101 tttcatcagg aaatgatgat gatttatcca aaaagacata gccaagtact gcgccgatta
    20161 aggcatgagc tgaaatagtg ctagttgttt taagatttaa tttttcacct aattgaataa
    20221 tgttgagaat ctctctatta atagcatcat cttcagaata ttcattcaag tgatataaaa
    20281 tacttgataa agccggatcc tttaatacaa agtcacgtgt cacatctgcg aatttgagga
    20341 gagcctcttt acctgaaacc cccatcaaat tttcaattaa tttttgatgt aaaactttaa
    20401 ttcgactcgc accaactaga gatattaatt gcttacgatt ggatacgtaa tggtaaagag
    20461 actgggatct cacgcctaat tctttagcaa gagctggcag agtagtctca gttaaccctt
    20521 tatctcgaat caactgaata gctttatcaa ttattttatt taaatctaaa cttctctttt
    20581 gcgtcatttc cacccctcct tgtcacgcat agtaaataat atatcactac acaatgaaga
    20641 ttacaatcta caaactgtaa ataactaaaa aagtagaaga tttctcttct actttttctt
    20701 tgccgtaaat gacgcattta ttgctttacc taattcatta aacttcttat tattgctact
    20761 ccatacgctc atgcaatatg aatgaccttg ggtttgaaca atcgcaacag ctgaatgatc
    20821 atccccaatt gcataaactc caccatttat tcctttaaca aagtttggtt tagaattcaa
    20881 agcttgcaaa agcaaactag catgtttctg atttaagatt cgtccctgat aaattccagc
    20941 cattgttttt actaaatcat gggctgtagt ctttccatag ggagctttac taaagttagc
    21001 agacattgta gtctgatcgg cacctagttt tttgataatg gcatcgattt tatcatgacc
    21061 aactttacga atcaaagcat tggcggcagt cttattaccg cgcatcattg cctgtcttaa
    21121 aaacgaaatc ccataagaca tattagtctt gagcgctttt tcaccattaa cgcgatcaga
    21181 tttcttaatt ttaattacag tcttagatgt taatttaccc tgttgctctt gttcataaat
    21241 tgctaaaagc aggtataatt tcatggtgtc atccacatta tgtgccacct tagtattagc
    21301 cactcggcaa aacttagctg aattatttaa atcttgaact gcaacttgat aactataatc
    21361 tttacccata atctgcttaa tcttttgagc aagcttcttt tgactacctg atgcaacttt
    21421 cacatggtta gcgtactcaa tagttttgat tttaggttct tttattttag gtttaggctc
    21481 ttttactttc ttcttcggac tagttttact agttttaggc tcaattatat taatgctagc
    21541 attcttgacc ctttttaaat tagcaaaata aagtgaaaaa gaaataattg ttgcaatcaa
    21601 agagacgata aatactttat tcttcattga ttttttcctt aaaagaagtg atgtttacgc
    21661 attaaaacta ctaaccagac catcagaaca atcattaata cagtaatgat tacccaatca
    21721 aacgggctat gaatcacagg aaggtccaca ttcattccat aaaaacctgt caagatcgtt
    21781 ggaatagtca acaccaaaga ccagacagtt aagaatttca tcgtgtcatt taggttattg
    21841 ttcatcatat tattagaagt cgccgacaaa gttttcgtta cttgttgcga aatctgaatc
    21901 atttcagccg cctgattaga ttcaatcaat acgtcatcta gccgttcatg ggccgtttta
    21961 gtaaatgaca attttgaatg atctaaacta tgaagcatca ttagatcagt ttgaatggaa
    22021 ctagataaat aaaccaaact cttttcaatg ttggacaatt caactaaatc cttattatca
    22081 atatcatcag ataatttttg atctaagcta tttctttcta catccagctg agtgactgct
    22141 ctttggaaat attgagaagc gtaaagcaaa aatatcatca agagctcagt cacatcttta
    22201 gcttcagata aacgctcacg catgggttca tcattaaatt catcaaagac ataactagtt
    22261 gattcagtat ggaaagtaaa aacattttct cccacaacta agaaagtaat tggatgagcc
    22321 gtaaaatgct taattgtatt agttggccaa ataggaacat catacaccaa taaatgactg
    22381 tgggtgtgaa catcgtagtc atagtgagga cgttcatgcc ggtcggagat atacgaaatg
    22441 atatctggag tgaaattgaa ttcatcttgc aaccgatcac tgtcttgctc acttaaatta
    22501 ctgatatcgt accatttgta ctttgt
//
