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Overview
1.1
1.2

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_CM001167.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1 | arylpolyene | 2,827,455 | 2,868,666 |
Region 2 | RRE-containing | 2,896,794 | 2,917,150 |

NZ_CM001167.1 - Region 1 - arylpolyene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,827,455 - 2,868,666 nt. (total: 41,212 nt) Show pHMM detection rules used
arylpolyene: (APE_KS1 or APE_KS2)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | arylpolyene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001897.1 |  | 0.22 | Polyketide | cepacin A | Burkholderia ambifaria IOP40-10
BGC0001075.1 |  | 0.19 | Terpene, Polyketide | aurachin RE | Rhodococcus erythropolis
BGC0000837.1 |  | 0.18 | Other | APE Vf | Aliivibrio fischeri ES114
BGC0002000.1 |  | 0.17 | Polyketide | setomimycin | Streptomyces aurantiacus JA 4570
BGC0000231.1 |  | 0.17 | Polyketide | griseusin | Streptomyces griseus
BGC0000228.1 |  | 0.16 | Polyketide | granaticin | Streptomyces violaceoruber
BGC0002008.1 |  | 0.16 | Other | aryl polyenes | Xenorhabdus doucetiae
BGC0000836.1 |  | 0.16 | Other | APE Ec | Escherichia coli CFT073
BGC0001895.1 |  | 0.15 | Polyketide | huanglongmycin A, huanglongmycin B, huanglongmycin C | Streptomyces sp. CB09001
BGC0000509.1 |  | 0.15 | RiPP | epilancin 15x | Staphylococcus epidermidis

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001897.1 |  | 0.54 | Polyketide | cepacin A | Burkholderia ambifaria IOP40-10
BGC0001075.1 |  | 0.52 | Terpene, Polyketide | aurachin RE | Rhodococcus erythropolis
BGC0000837.1 |  | 0.50 | Other | APE Vf | Aliivibrio fischeri ES114
BGC0002000.1 |  | 0.49 | Polyketide | setomimycin | Streptomyces aurantiacus JA 4570
BGC0000231.1 |  | 0.48 | Polyketide | griseusin | Streptomyces griseus
BGC0000228.1 |  | 0.47 | Polyketide | granaticin | Streptomyces violaceoruber
BGC0002008.1 |  | 0.47 | Other | aryl polyenes | Xenorhabdus doucetiae
BGC0000836.1 |  | 0.46 | Other | APE Ec | Escherichia coli CFT073
BGC0001895.1 |  | 0.45 | Polyketide | huanglongmycin A, huanglongmycin B, huanglongmycin C | Streptomyces sp. CB09001
BGC0000509.1 |  | 0.45 | RiPP | epilancin 15x | Staphylococcus epidermidis

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CM001167.1 - Region 2 - RRE-containing
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,896,794 - 2,917,150 nt. (total: 20,357 nt) Show pHMM detection rules used
RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RRE-containing | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001361.1 |  | 0.26 | Terpene | sodorifen | Serratia plymuthica 4Rx13
BGC0001594.1 |  | 0.19 | Alkaloid | fischerindole L | Fischerella muscicola UTEX 1829
BGC0001588.1 |  | 0.17 | Saccharide | exopolysaccharides | Burkholderia pseudomallei 1026b
BGC0001589.1 |  | 0.17 | Saccharide | exopolysaccharides | Burkholderia cenocepacia J2315
BGC0001120.1 |  | 0.16 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0000668.1 |  | 0.16 | Terpene, Alkaloid | 12-epi-hapalindole C isonitrile, 12-epi-hapalindole E, 12-epi-fischerindole U isonitrile, fischerindole L, 12-epi-fischerindole I isonitrile, welwitindolinone A isonitrile, welwitindolinone B isothiocyanate, welwitindolinone C isothiocyanate, N-methylwelwitindolinone C isothiocyanate, N-methylwelwitinsolinone C isonitrile, 3-epi-welwitindolinone B isothiocyanate, 3-(Z-2'-isocyanoethenyl)-indole | Hapalosiphon welwitschii UTEX B 1830
BGC0001664.1 |  | 0.16 | Terpene | merosterol | Scytonema sp. PCC 10023
BGC0001501.1 |  | 0.15 | Alkaloid | ambiguine P | Fischerella sp. TAU
BGC0000666.1 |  | 0.15 | Terpene | xiamycin A | Streptomyces sp. SCSIO 02999
BGC0000665.1 |  | 0.15 | Terpene, Alkaloid | xiamycin | Streptomyces sp. HKI0576

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001361.1 |  | 0.60 | Terpene | sodorifen | Serratia plymuthica 4Rx13
BGC0001594.1 |  | 0.51 | Alkaloid | fischerindole L | Fischerella muscicola UTEX 1829
BGC0001588.1 |  | 0.48 | Saccharide | exopolysaccharides | Burkholderia pseudomallei 1026b
BGC0001589.1 |  | 0.48 | Saccharide | exopolysaccharides | Burkholderia cenocepacia J2315
BGC0001120.1 |  | 0.47 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0000668.1 |  | 0.47 | Terpene, Alkaloid | 12-epi-hapalindole C isonitrile, 12-epi-hapalindole E, 12-epi-fischerindole U isonitrile, fischerindole L, 12-epi-fischerindole I isonitrile, welwitindolinone A isonitrile, welwitindolinone B isothiocyanate, welwitindolinone C isothiocyanate, N-methylwelwitindolinone C isothiocyanate, N-methylwelwitinsolinone C isonitrile, 3-epi-welwitindolinone B isothiocyanate, 3-(Z-2'-isocyanoethenyl)-indole | Hapalosiphon welwitschii UTEX B 1830
BGC0001664.1 |  | 0.46 | Terpene | merosterol | Scytonema sp. PCC 10023
BGC0001501.1 |  | 0.45 | Alkaloid | ambiguine P | Fischerella sp. TAU
BGC0000666.1 |  | 0.44 | Terpene | xiamycin A | Streptomyces sp. SCSIO 02999
BGC0000665.1 |  | 0.44 | Terpene, Alkaloid | xiamycin | Streptomyces sp. HKI0576

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names