LOCUS       NZ_CP084663.1          18445 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP084663.1 UNVERIFIED_ORG: Clostridium sporogenes strain
            FDAARGOS_1532 plasmid unnamed, complete sequence.
ACCESSION   NZ_CP084663
VERSION     NZ_CP084663.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 15:46:14
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 26998
            Orig. end    :: 45443
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..18445
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[36998:39773](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12775
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     cand_cluster    1..18445
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..18445
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     CDS             complement(1010..2317)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_39"
                     /sec_met_domain="PF04055 (E-value: 4.1e-13, bitscore: 41.8,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 5e-11, bitscore: 34.8,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 3.7e-18, bitscore:
                     57.6, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFKKSLYNILIEQSDGETLIFNTYSTALAVLNSNQKKIYNNIELK
                     ETNEQNEDINFLKQNGFIVMSDIDEFKRLCVEERTNRFDKSILNLTIAPTMACNMACSY
                     CYEEKYAKFMDDDIINKLIDFVNKKISENQLKQINIIWYGGEPLLSIDVLKKISSQIIS
                     LCNENSIQYSSSIVTNGVLLDIDTAKMLKEQCNVTNAQITIDGLRDLHNKRRRLKNNKD
                     SFDIILKNIDDIKDIINITIRVNIDKKNVMEINKLVDYLIDYKKFGNKVKINFYPIVVK
                     NTDFCSVQKNDCLDPKEFGKEETILINKLYAKGALKSIYKLQPLYSSVFCTAVCNNSFV
                     IDPEGFLYPCWDFIGVKEKSIGNISNEKISISNEYCKWLLLDIPQQCSNCKLVPMCKGG
                     CPSARLYDNKPHCDPRIMSLEQKLCISYDNFKNTLN"
     aSDomain        complement(1094..1327)
                     /aSDomain="TIGR04085"
                     /aSTool="tigrfam"
                     /description="rSAM_more_4Fe4S: radical SAM additional
                     4Fe4S-binding SPASM domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg2_39_0001"
                     /evalue="3.10E-16"
                     /identifier="TIGR04085"
                     /label="ctg2_39"
                     /locus_tag="ctg2_39"
                     /protein_end="408"
                     /protein_start="330"
                     /score="57.6"
                     /tool="antismash"
                     /translation="CTAVCNNSFVIDPEGFLYPCWDFIGVKEKSIGNISNEKISISNEY
                     CKWLLLDIPQQCSNCKLVPMCKGGCPSARLYDN"
     PFAM_domain     complement(1667..2029)
                     /aSDomain="Fer4_12"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13353.8"
                     /description="4Fe-4S single cluster domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_39_0001"
                     /evalue="7.30E-08"
                     /label="ctg2_39"
                     /locus_tag="ctg2_39"
                     /protein_end="217"
                     /protein_start="96"
                     /score="33.1"
                     /tool="antismash"
                     /translation="ACNMACSYCYEEKYAKFMDDDIINKLIDFVNKKISENQLKQINII
                     WYGGEPLLSIDVLKKISSQIISLCNENSIQYSSSIVTNGVLLDIDTAKMLKEQCNVTNA
                     QITIDGLRDLHNKRRRL"
     CDS             2886..3431
                     /locus_tag="ctg2_40"
                     /transl_table=11
                     /translation="MRKWKRIYKIIFIILILIFLVFERFYLFIPNINPTYSKDIDRTNL
                     NQVISDYIINNYIINNYGISKDQFNYKRFESHKVYKIKPRYGLQYVYIYTLYGIYELEN
                     GKYQLGSGGANPLVIIVNKGKNDRYSVLGYKDFDDIDDNNINLPPTERKIFNEIDTDKL
                     LKELNNDIYSQMQGKLGI"
     CDS             complement(3488..4156)
                     /locus_tag="ctg2_41"
                     /transl_table=11
                     /translation="MNYINAFLHKELWEIKSSWKKLMWMSFIVLLPLIFLYNSRFEIIP
                     KQMQPIYLVTLVAFAVSGQLSSNSLIREKNYKTLDIILCDNIPKYSVVIGKILPATIIG
                     YIYCIVSLLLLKITVFSIYGSNLRIEITQLFIILPLAIAYLGSSASVLANLIIRDERVI
                     SLMSLIICLLVSGCVYLVNTHILQINIYINSLLILILSFVLNIISVFILKHSSSLLIKF
                     "
     CDS             complement(4161..4862)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 175.3; E-value:
                     2.7e-53)"
                     /gene_kind="transport"
                     /locus_tag="ctg2_42"
                     /transl_table=11
                     /translation="MLKIKNIAFKYNKQKVLDHVSCEIKSGDVFALLGHNGAGKTTMFR
                     IIMGLLPPSNGQVIFTDTNMKKKGFNYISFLPENNGIYENLTAYRNLEFRGRISNLPLK
                     IIKENSQKLLKKFKLINRGNEKAYTWSNGMKKRLGLASAMITKPRILILDEPTNGIDPE
                     SLNILTKTMKELQDEGTTIIFSSHNLDFVSKVSTKVMILQNGKKVFSSEMKNINEPLEN
                     LYLKHTESLEE"
     PFAM_domain     complement(4389..4814)
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_42_0002"
                     /evalue="5.30E-27"
                     /label="ctg2_42"
                     /locus_tag="ctg2_42"
                     /protein_end="158"
                     /protein_start="16"
                     /score="95.1"
                     /tool="antismash"
                     /translation="LDHVSCEIKSGDVFALLGHNGAGKTTMFRIIMGLLPPSNGQVIFT
                     DTNMKKKGFNYISFLPENNGIYENLTAYRNLEFRGRISNLPLKIIKENSQKLLKKFKLI
                     NRGNEKAYTWSNGMKKRLGLASAMITKPRILILDEPTN"
     CDS             5091..5474
                     /locus_tag="ctg2_43"
                     /transl_table=11
                     /translation="LIFVIITSVVYKYVNKKVKLNINNIKRIDVIKLPVPPKKKVVTKK
                     EDIVEIINFINSIQLLEEINDPVKGWIYTINIYNNSNNTNNTIEFLGDKINIYNKWYKI
                     NDNNLEKLRKIYKDLNYEQASFP"
     CDS             complement(5657..5824)
                     /locus_tag="ctg2_44"
                     /transl_table=11
                     /translation="MKSKVLSVTCSLFTFVIFIVLSKITNLGIIKSAIISFCSSIIIFM
                     LFIIIFSNKK"
     CDS             complement(6713..6877)
                     /gene="allorf_33711_33875"
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="allorf_33711_33875"
                     /protein_id="allorf_33711_33875"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MLLTLKELSLLIFLTVLHTALLCPSKSICLCNLLCISVCLTPLLF
                     IDFITFSLF"
     CDS_motif       complement(6818..6877)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MLLTLKELSLLIFLTVLHTA"
                     /locus_tag="allorf_33711_33875_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(6713..6817)
                     /prepeptide="core"
                     /locus_tag="allorf_33711_33875_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.90"
                     /molecular_weight="3686.6"
                     /monoisotopic_mass="3684.0"
                     /core_sequence="LLCPSKSICLCNLLCISVCLTPLLFIDFITFSLF"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MLLTLKELSLLIFLTVLHTA"
                     /leader_location="[6817:6877](-)"
                     /alternative_weights="3704.6"
     CDS             7425..8144
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 206.4; E-value:
                     8.2e-63)"
                     /gene_kind="transport"
                     /locus_tag="ctg2_45"
                     /transl_table=11
                     /translation="MIEVKNLAKIFKNGVTAVNNINFKVTDGEILGLLGENGAGKTTTL
                     RMLATMLKITEGQALINGHDVSKEADKVRGQIGILFGGEVGLYDRLTARENIKYFAELN
                     GMSEEETNKSIEELAKNLDMTEYLDRRVGKFSRGMKQKVAIARSIVHNPSVVLFDEPTI
                     GLDVTSAKIVQDFILKCKSDGRTIIFSSHTIPEVEKLCDRIVIIHKGKIVEEGKLKELE
                     EKYNNSIEEIFVNLIAK"
     PFAM_domain     7476..7910
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_45_0003"
                     /evalue="2.00E-32"
                     /label="ctg2_45"
                     /locus_tag="ctg2_45"
                     /protein_end="162"
                     /protein_start="17"
                     /score="112.7"
                     /tool="antismash"
                     /translation="VNNINFKVTDGEILGLLGENGAGKTTTLRMLATMLKITEGQALIN
                     GHDVSKEADKVRGQIGILFGGEVGLYDRLTARENIKYFAELNGMSEEETNKSIEELAKN
                     LDMTEYLDRRVGKFSRGMKQKVAIARSIVHNPSVVLFDEPT"
     CDS             8158..9336
                     /locus_tag="ctg2_46"
                     /transl_table=11
                     /translation="MKNVVGVVLKKELLDLFRDKKTLILSILIPIILLPIMSFGIGKVA
                     KSDSDKVQNNLKIVIVDQGESSFSKFIKSHKNVNIINSKNIDKDIKEGDVYVQIKIPKG
                     FDENISKNFNEKIELKYDNSSNDAMTAVSMIKNYIEEYSKQIVSKRLEKSNIDQSILTP
                     INIVDNVVGNKEEGLGKIMAAMLIPLLLMLYSATSTIGASVDLGAGEKERGTLEPLLTT
                     KAGRTSLLVGKFLTITIMGILMSCAYLIGIIITMKQPNGMFGNAGLNLGTATLVLIMIL
                     PILYTMVFGALQLAISIYARSFKEAQTYLSPITVIAIVLIYMVMMKDPKSIPIVYFNIP
                     LTNGVCVMKEFLAGIYNYTHIAITFGWIVFYIFLAILFARYMFSKEEVIFRT"
     PFAM_domain     8179..9318
                     /aSDomain="ABC2_membrane_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12679.9"
                     /description="ABC-2 family transporter protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_46_0004"
                     /evalue="1.90E-27"
                     /label="ctg2_46"
                     /locus_tag="ctg2_46"
                     /protein_end="387"
                     /protein_start="7"
                     /score="96.3"
                     /tool="antismash"
                     /translation="VLKKELLDLFRDKKTLILSILIPIILLPIMSFGIGKVAKSDSDKV
                     QNNLKIVIVDQGESSFSKFIKSHKNVNIINSKNIDKDIKEGDVYVQIKIPKGFDENISK
                     NFNEKIELKYDNSSNDAMTAVSMIKNYIEEYSKQIVSKRLEKSNIDQSILTPINIVDNV
                     VGNKEEGLGKIMAAMLIPLLLMLYSATSTIGASVDLGAGEKERGTLEPLLTTKAGRTSL
                     LVGKFLTITIMGILMSCAYLIGIIITMKQPNGMFGNAGLNLGTATLVLIMILPILYTMV
                     FGALQLAISIYARSFKEAQTYLSPITVIAIVLIYMVMMKDPKSIPIVYFNIPLTNGVCV
                     MKEFLAGIYNYTHIAITFGWIVFYIFLAILFARYMFSKEE"
     CDS             9381..9728
                     /locus_tag="ctg2_47"
                     /transl_table=11
                     /translation="MNIEKLIEEFGKTLGKVIFNKKEEKSEKVNINQLSSTDIFKINFN
                     KLFHEGNYNKAEDLIFDELERNNSPEVYEVAIKFYNLLANKSDKELNESNFPRNEIYKG
                     LHDIQKFKIDL"
     PFAM_domain     9387..9710
                     /aSDomain="DUF6483"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF20092.1"
                     /description="Family of unknown function (DUF6483)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_47_0005"
                     /evalue="3.50E-27"
                     /label="ctg2_47"
                     /locus_tag="ctg2_47"
                     /protein_end="110"
                     /protein_start="2"
                     /score="95.3"
                     /tool="antismash"
                     /translation="IEKLIEEFGKTLGKVIFNKKEEKSEKVNINQLSSTDIFKINFNKL
                     FHEGNYNKAEDLIFDELERNNSPEVYEVAIKFYNLLANKSDKELNESNFPRNEIYKGLH
                     DIQK"
     CDS             10001..12775
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070:lanthionine synthetase C family protein (Score:
                     661.1; E-value: 4.7e-200)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_48"
                     /sec_met_domain="LANC_like (E-value: 2.2e-45, bitscore:
                     146.6, seeds: 47, tool: rule-based-clusters)"
                     /sec_met_domain="DUF4135 (E-value: 2.5e-90, bitscore:
                     295.1, seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHLFFDTVPKENIMFPDFFSLYLEKFDYKFNVLYKNKNKNVSFNG
                     IYSYLYTSLLNCSIRTLIRELHNYKAKNLLSGDTSKERFLSFEKITKNKSFITYLYQEY
                     PELKSLLEQKITQTALYVCEIMNNFEKDKLELQKNFQKNFEKIIDIHLGKGDTHNGGKS
                     VAIIESNCGKIVYKPHNLSPDIVFENIISWVNLKNILKCKLNSLKVIDYDNYGWQEFVR
                     YEECENYIEVQNYYYRSGCFLAIFYTLGTNDIHFENVIVNGEYPCFIDLETLVGINRPG
                     QISSVLATGFIPNKSLNNLFDIDLSGLCGKMQTSSKLTTIAITNPKTDEMIVESQPAKI
                     YCNNNIVKLNNKSVKIENYTSVFITGFKDTLELIINNKIEYISLIEKEFNKFQKFRQVI
                     RHTQVYSKFLIAASHPDYLKSENKRMELFKRLYNGCENEREHKRISNEINTLFKWDIPY
                     YYCNYDSKDLFSDNITICKNYFQSTVKKSLYNKIERINSEIENFQIDVIKKSLFTVYED
                     QFMNNKFNRVKIYNNNNKVSHEEIIMKISNDISSNILELEDNNKVSFLINIIQNNQVLL
                     SPINFNLYEGGGIIWLFASLGKLFNNKYYEKMSIKLLESSILTYEYYDKKQNNIEKISA
                     FFGIGSLMYLYYNISVLYNNKEYYYKFIDVANKILEYNCDHLEESNNSLDYDFVCGISG
                     ILVLSVKIYLKEKNYLMKKIIDRYSDYLFKFINNNIKDLNKIGLAHGLSGYSLALIMIY
                     YAKQDKVYLDLATKLINKENLIYSNDENVDKIKTSWCNGQTGMALVRSEILKINYDKNI
                     SNDILKYLRNMVTDGFYNMNSMCLCHGIYGNIEIVNKIINNINQTNKIITHDEVTEFET
                     KLISNINDIQLGFKNNFMLDTFMAGSSGIAYAKLRLLYPEMPSILSLDIIKDF"
     aSDomain        10049..12730
                     /aSDomain="TIGR03897"
                     /aSTool="tigrfam"
                     /description="lanti_2_LanM: type 2 lantibiotic biosynthesis
                     protein LanM"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg2_48_0002"
                     /evalue="1.30E-185"
                     /identifier="TIGR03897"
                     /label="ctg2_48"
                     /locus_tag="ctg2_48"
                     /protein_end="910"
                     /protein_start="16"
                     /score="616.8"
                     /tool="antismash"
                     /translation="DFFSLYLEKFDYKFNVLYKNKNKNVSFNGIYSYLYTSLLNCSIRT
                     LIRELHNYKAKNLLSGDTSKERFLSFEKITKNKSFITYLYQEYPELKSLLEQKITQTAL
                     YVCEIMNNFEKDKLELQKNFQKNFEKIIDIHLGKGDTHNGGKSVAIIESNCGKIVYKPH
                     NLSPDIVFENIISWVNLKNILKCKLNSLKVIDYDNYGWQEFVRYEECENYIEVQNYYYR
                     SGCFLAIFYTLGTNDIHFENVIVNGEYPCFIDLETLVGINRPGQISSVLATGFIPNKSL
                     NNLFDIDLSGLCGKMQTSSKLTTIAITNPKTDEMIVESQPAKIYCNNNIVKLNNKSVKI
                     ENYTSVFITGFKDTLELIINNKIEYISLIEKEFNKFQKFRQVIRHTQVYSKFLIAASHP
                     DYLKSENKRMELFKRLYNGCENEREHKRISNEINTLFKWDIPYYYCNYDSKDLFSDNIT
                     ICKNYFQSTVKKSLYNKIERINSEIENFQIDVIKKSLFTVYEDQFMNNKFNRVKIYNNN
                     NKVSHEEIIMKISNDISSNILELEDNNKVSFLINIIQNNQVLLSPINFNLYEGGGIIWL
                     FASLGKLFNNKYYEKMSIKLLESSILTYEYYDKKQNNIEKISAFFGIGSLMYLYYNISV
                     LYNNKEYYYKFIDVANKILEYNCDHLEESNNSLDYDFVCGISGILVLSVKIYLKEKNYL
                     MKKIIDRYSDYLFKFINNNIKDLNKIGLAHGLSGYSLALIMIYYAKQDKVYLDLATKLI
                     NKENLIYSNDENVDKIKTSWCNGQTGMALVRSEILKINYDKNISNDILKYLRNMVTDGF
                     YNMNSMCLCHGIYGNIEIVNKIINNINQTNKIITHDEVTEFETKLISNINDIQLGFKNN
                     FMLDTFMAGSSGIAYAKLRLLYP"
     PFAM_domain     10310..11383
                     /aSDomain="DUF4135"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13575.8"
                     /description="Domain of unknown function (DUF4135)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_48_0006"
                     /evalue="8.30E-92"
                     /label="ctg2_48"
                     /locus_tag="ctg2_48"
                     /protein_end="461"
                     /protein_start="103"
                     /score="308.4"
                     /tool="antismash"
                     /translation="YPELKSLLEQKITQTALYVCEIMNNFEKDKLELQKNFQKNFEKII
                     DIHLGKGDTHNGGKSVAIIESNCGKIVYKPHNLSPDIVFENIISWVNLKNILKCKLNSL
                     KVIDYDNYGWQEFVRYEECENYIEVQNYYYRSGCFLAIFYTLGTNDIHFENVIVNGEYP
                     CFIDLETLVGINRPGQISSVLATGFIPNKSLNNLFDIDLSGLCGKMQTSSKLTTIAITN
                     PKTDEMIVESQPAKIYCNNNIVKLNNKSVKIENYTSVFITGFKDTLELIINNKIEYISL
                     IEKEFNKFQKFRQVIRHTQVYSKFLIAASHPDYLKSENKRMELFKRLYNGCENEREHKR
                     ISNEINTLFKWDIPYYYC"
     PFAM_domain     11732..12745
                     /aSDomain="LANC_like"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05147.15"
                     /description="Lanthionine synthetase C-like protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_48_0007"
                     /evalue="7.00E-42"
                     /label="ctg2_48"
                     /locus_tag="ctg2_48"
                     /protein_end="915"
                     /protein_start="577"
                     /score="143.4"
                     /tool="antismash"
                     /translation="PINFNLYEGGGIIWLFASLGKLFNNKYYEKMSIKLLESSILTYEY
                     YDKKQNNIEKISAFFGIGSLMYLYYNISVLYNNKEYYYKFIDVANKILEYNCDHLEESN
                     NSLDYDFVCGISGILVLSVKIYLKEKNYLMKKIIDRYSDYLFKFINNNIKDLNKIGLAH
                     GLSGYSLALIMIYYAKQDKVYLDLATKLINKENLIYSNDENVDKIKTSWCNGQTGMALV
                     RSEILKINYDKNISNDILKYLRNMVTDGFYNMNSMCLCHGIYGNIEIVNKIINNINQTN
                     KIITHDEVTEFETKLISNINDIQLGFKNNFMLDTFMAGSSGIAYAKLRLLYPEMPSI"
     CDS             12849..13580
                     /locus_tag="ctg2_49"
                     /transl_table=11
                     /translation="MKKLVSIIGSHKGYNSKTYDIAYKVSEGLKNKNNNISSEFFILSE
                     LDINKCTGCLGCFTKCSSCVIFNDSMSILEKSMFDADIIIFGSPVYAHNITGDMKIFID
                     RLCHLLHIMGLCGKYGVTVSTSSSNGNTFVDNYLFKIMEYLGIRVVDQISYVSYHKFED
                     KHITKCVDKIDGILNNKILLPPSEFQEQIFNIYKKIYFKSYEESIINKNVVKNQEACYW
                     HDNGYFNYNSFEELFNIMKNK"
     PFAM_domain     12855..13316
                     /aSDomain="FMN_red"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03358.17"
                     /description="NADPH-dependent FMN reductase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_49_0008"
                     /evalue="1.10E-18"
                     /label="ctg2_49"
                     /locus_tag="ctg2_49"
                     /protein_end="156"
                     /protein_start="2"
                     /score="67.5"
                     /tool="antismash"
                     /translation="KLVSIIGSHKGYNSKTYDIAYKVSEGLKNKNNNISSEFFILSELD
                     INKCTGCLGCFTKCSSCVIFNDSMSILEKSMFDADIIIFGSPVYAHNITGDMKIFIDRL
                     CHLLHIMGLCGKYGVTVSTSSSNGNTFVDNYLFKIMEYLGIRVVDQISYV"
     CDS             13664..13843
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_50"
                     /transl_table=11
                     /translation="MTKNFDPAGIVDLKELDELAHIGGSDVEAQTTPTIASVLVSVISV
                     ELTVSAATVTAQCL"
     CDS_motif       13664..13738
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MTKNFDPAGIVDLKELDELAHIGGS"
                     /locus_tag="ctg2_50_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       13739..13843
                     /prepeptide="core"
                     /locus_tag="ctg2_50_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-2.30"
                     /molecular_weight="3237.7"
                     /monoisotopic_mass="3235.8"
                     /core_sequence="DVEAQTTPTIASVLVSVISVELTVSAATVTAQCL"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTKNFDPAGIVDLKELDELAHIGGS"
                     /leader_location="[13663:13738](+)"
                     /alternative_weights="3255.7"
                     /alternative_weights="3273.7"
                     /alternative_weights="3291.7"
                     /alternative_weights="3309.8"
                     /alternative_weights="3327.8"
                     /alternative_weights="3345.8"
                     /alternative_weights="3363.8"
                     /alternative_weights="3381.8"
                     /alternative_weights="3399.9"
     CDS             13997..15040
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075:alkaline serine protease, subtilase family
                     (Score: 239.5; E-value: 1.4e-72)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_51"
                     /sec_met_domain="Peptidase_S8 (E-value: 1.7e-44, bitscore:
                     144.0, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VSSLNNKYERWRWDIDKVTNNRKSYKIQQGNHTVKVAIIDSGIDK
                     NHPDLKNNIISNKSFIPQNNSLEDTFGHGTMVAGEIAANGNVKGVAPRIGIASYKVFDG
                     TNCESIWVINAIIEAANDGMDVINLSLGTYKSILDKKDIYILLAYKKAIEYAQSKNCIV
                     ITASGTRLKGVDISNPFKLSKNLGNKNDLKIYLPGGLPNVITVSATNKNDELAYYSNYG
                     NTVQIAAPAGDYGPNYQTQKITNFKYMTLVTYPTGLPQSQLSLSMGFKKGYEFIEGGTS
                     IAAAKVSAAAALLIAQYNETYGFKPSRLKVEKLLYDGVTPAVKRDTEIYFGKGILNVEN
                     SLNLIKN"
     PFAM_domain     14093..14908
                     /aSDomain="Peptidase_S8"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00082.24"
                     /description="Subtilase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_51_0009"
                     /evalue="6.30E-49"
                     /label="ctg2_51"
                     /locus_tag="ctg2_51"
                     /protein_end="304"
                     /protein_start="32"
                     /score="166.8"
                     /tool="antismash"
                     /translation="TVKVAIIDSGIDKNHPDLKNNIISNKSFIPQNNSLEDTFGHGTMV
                     AGEIAANGNVKGVAPRIGIASYKVFDGTNCESIWVINAIIEAANDGMDVINLSLGTYKS
                     ILDKKDIYILLAYKKAIEYAQSKNCIVITASGTRLKGVDISNPFKLSKNLGNKNDLKIY
                     LPGGLPNVITVSATNKNDELAYYSNYGNTVQIAAPAGDYGPNYQTQKITNFKYMTLVTY
                     PTGLPQSQLSLSMGFKKGYEFIEGGTSIAAAKVSAAAALLIAQYNETYGF"
     CDS             15776..16363
                     /locus_tag="ctg2_52"
                     /transl_table=11
                     /translation="MKKTLKKITIICISLIVTFLIHREITTELIYNYIFITNNNIETIV
                     HIGAILIQFMCFYLIIREIINQRVDKLFYKTLWFCYFIVLSFLLFGRARGFQGFQECNT
                     NPLHFIENFESNKDSLIITIMNILFFIPIGYLFRHKRYIISILIICLSIESIQYIFSLG
                     IFDICDIIFNIIGFFIGYLSCKNKNFNSITVS"
     PFAM_domain     16007..16330
                     /aSDomain="VanZ"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04892.14"
                     /description="VanZ like family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_52_0010"
                     /evalue="3.40E-13"
                     /label="ctg2_52"
                     /locus_tag="ctg2_52"
                     /protein_end="185"
                     /protein_start="77"
                     /score="50.4"
                     /tool="antismash"
                     /translation="WFCYFIVLSFLLFGRARGFQGFQECNTNPLHFIENFESNKDSLII
                     TIMNILFFIPIGYLFRHKRYIISILIICLSIESIQYIFSLGIFDICDIIFNIIGFFIGY
                     LSCK"
     CDS             complement(17497..18444)
                     /locus_tag="ctg2_53"
                     /transl_table=11
                     /translation="EDFKPYKFMISDFMKLINVNTKTKYIEIPKITKELMKKVFEINEG
                     DTLIQTAWLSSATYKKGSGIVELEFSPKLKPYMLKLNSMFTQYKLENILTMKSKYSPRI
                     YEILKCNEFKKQGYIELEIEDLRKLLKAENVYPLYANFKQKLLKSTQKELKEKTDISFE
                     FEEIKTGRKVTALRFYIKSKKQNNIAKEEICATFEETNYIEQVKSIFHEEISSLQAKQI
                     FDVSKRNIELIKEKYQIAKQTNNINNLVGWIIEALKRDYKEPIGKTKVDKFNDFEQRQY
                     DFVDLERKLLGWNKTEESIELNEQKTKEFYYFNF"
     PFAM_domain     complement(17905..18441)
                     /aSDomain="Rep_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01051.23"
                     /description="Initiator Replication protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_53_0011"
                     /evalue="7.00E-43"
                     /label="ctg2_53"
                     /locus_tag="ctg2_53"
                     /protein_end="180"
                     /protein_start="1"
                     /score="147.1"
                     /tool="antismash"
                     /translation="DFKPYKFMISDFMKLINVNTKTKYIEIPKITKELMKKVFEINEGD
                     TLIQTAWLSSATYKKGSGIVELEFSPKLKPYMLKLNSMFTQYKLENILTMKSKYSPRIY
                     EILKCNEFKKQGYIELEIEDLRKLLKAENVYPLYANFKQKLLKSTQKELKEKTDISFEF
                     EEIKTGRKVTALRFYI"
ORIGIN
        1 taaaaaacta attattatta aatttatata aggaataaag ttagatttaa atagatcaat
       61 ataaacatta ctattagtta tagataatat aaaaaacaat atacatatac aagatatatc
      121 taaaaataat attttaccta attgaaactt ttcagataaa atattacaaa gtattggggc
      181 taaaaaaact gataaaattg atattgaatt taacattcct aattgataat ctgacacaga
      241 caaatttatt ttagctatat aattaaatcc aattgataca ataggagtat atacaaaatt
      301 tataactaat ccaagaatag caatattcaa taacatagat tcagatttat tttttaaaaa
      361 tataagccct tctttgaaat cttttataaa ttgttttaca gtaacttctt tataaatata
      421 atttttagga atatttataa ataactcact tatagaagat ataaaaaaac aaatagaatt
      481 tagaattaaa attattgaaa tcccatatat cccaaataaa tatcctgcta tgagaggagc
      541 aacaaaagta gctatacttc taaatatatt attaaaacca ttagcactta ttaagacttc
      601 tttatcaata atggatggaa taatggtgct tatagctgga ttaaatattg ctgatattat
      661 tgaaagaatt attacaagta aataaatact ataaatactt aaagaattat ttgattgaaa
      721 gtataaataa tatcctccta atataagaaa attaataaaa tctaatgaaa ctattatttt
      781 ttttctatct acccaatcta ctataactcc agcaatagga gttataatta actgtggtat
      841 aatagaaatt gctaaaactg atgcaaattt agtagcagat ccagttgtat ttagcacata
      901 tagagataaa gaaaatgata atgcctgtgt acccaacaat gatgtaaaat tacccaaaat
      961 taaaagaata aaacttttat tttttagcaa tacattattc attataatct caattcaaag
     1021 tatttttaaa attatcataa gaaatacata acttttgttc taaactcata attctaggat
     1081 cacagtgtgg tttattatca tataatctgg cagaaggaca accaccttta cacataggga
     1141 ctaatttaca gtttgagcat tgctgaggaa tatctaacaa aagccattta caatattcat
     1201 tacttattga tattttttca ttagaaatat taccgatact cttttcttta actcctatga
     1261 aatcccaaca aggatataaa aatccttctg gatctataac aaaagaatta ttacatacag
     1321 cggtacaaaa cacagaagaa tatagaggtt gtaatttata tattgacttt agagctcctt
     1381 tggcatataa cttattaatt aaaatagttt cttctttacc aaattcttta ggatcaagac
     1441 aatcgttctt ctgtacacta caaaaatcag tatttttaac tactattgga taaaaattta
     1501 tttttacttt attaccaaat tttttataat ctattaagta gtcaactagc ttgtttattt
     1561 ccattacatt ttttttatct atatttactc taattgtaat atttataata tctttaatat
     1621 catcaatatt cttaagaata atatcaaaac tatctttatt attttttagt cttcttcgtt
     1681 tgttatgaag atcccttaat ccatcaatag taatttgtgc attagtaaca ttacattgct
     1741 cttttaacat tttagctgta tctatatcaa gtaatactcc attggtaaca attgaagaag
     1801 aatattgtat actattttca ttacataaag agattatttg ggaagatatt ttctttaata
     1861 catctataga aagtaatggc tcgcccccat accaaattat attaatttgt tttaattgat
     1921 tttcactaat ttttttatta acaaaatcaa ttaatttatt aataatatca tcatccataa
     1981 atttagcata tttttcttca taacaatagg aacatgccat gttacaggcc attgttggag
     2041 ctatggtaag atttaaaatt gatttatcaa atctattagt tctctcttct acacacaagc
     2101 gtttaaattc atcaatatca ctcattacaa taaatccatt ttgttttaga aaatttatat
     2161 cttcattttg ttcattagtt tcttttaatt ctatattatt atatattttt ttttgatttg
     2221 aattaagaac tgccaaagct gtagaatatg tgttaaatat taaagtctct ccatcagatt
     2281 gttctattaa tatattgtaa agtgattttt taaacattaa taattccccc caataagtca
     2341 aaatgaggta ataaagcaaa attataaaaa tgctttatta cctcatttca tattagccta
     2401 tttgaactcc acaacctaca actactcctc caccaggttt acaacaactt gtaattaaca
     2461 ttaaaatccc cccttttcaa tatataattt aactagttaa ttatataaaa tcctgatatc
     2521 attataataa caataatacc ttttttagta aaagtcaata tttttttaca gatattttta
     2581 ataaaatagc aaaaattatt gactttttat taaaaattaa taatttttat taaaaattta
     2641 atgaaatatt aataaatatt taacaaagct aaggtaagga agtataaaca ttttattaaa
     2701 agttttaata agcactcatt gaattcagtt ataaacggta aaatttatta ttggtgctag
     2761 tatactattc tagacacaga aatccgagca tattaaaatg taaataaaag aaggatgtgt
     2821 taaaatggca agaggtaaaa aacaatatac agaggaattt aaaattataa ggggataaac
     2881 tttaaatgag gaaatggaaa agaatttata aaataatttt tattatactg atattaattt
     2941 ttttagtatt tgaaaggttt tatttattca tacctaacat taatcccaca tattctaaag
     3001 atatagatag aactaattta aaccaagtta tatcggatta tattattaat aattacatta
     3061 ttaataatta tggtatttca aaagatcaat ttaattataa aagatttgaa agtcataaag
     3121 tttataaaat aaagccaaga tatggtttgc agtatgtata tatttatact ttatatggaa
     3181 tatacgaatt agaaaatggg aaatatcaac ttggcagtgg aggagcaaat cctttagtta
     3241 taatagtaaa taaaggtaag aacgatagat attctgtttt aggatataaa gattttgatg
     3301 atattgatga taataatatt aatttaccac ctactgaaag aaagatattt aatgaaatag
     3361 acactgataa attattaaaa gagttaaaca atgatatata ttctcaaatg caaggaaaat
     3421 taggtattta aagaagatat aaaacattaa tagaaatgtc ttatatcttc ttattgatgt
     3481 gtaattttta aaacttaatt aataatgacg agctatgttt taaaataaag acagaaatta
     3541 tatttaaaac aaagcttagt attaaaatta ataatgagtt tatatatata ttaatttgta
     3601 aaatatgtgt attaactaaa tatacacatc cagatacaag taaacagata ataagtgaca
     3661 ttaagcttat aactctctcg tctcttatta tcaaatttgc taaaacactt gctgaacttc
     3721 ctaagtaagc tatagccagt gggagtataa taaataattg agttatttct attcttaaat
     3781 tactaccgta aatagaaaat acagtgattt ttaacaacaa taaagataca atacaatata
     3841 tataaccaat aattgttgct gggagtattt tacctataac aacagaatac ttaggtatat
     3901 tgtcacataa aataatatcc aatgttttat agtttttttc acgtataaga gaattggatg
     3961 aaagttgtcc acttacagca aatgcaacaa gggtgactaa atatattggt tgcatttgtt
     4021 ttggtataat ttcaaatcta ctattatata aaaaaatcaa tggaagtaat acaataaaag
     4081 acatccacat tagttttttc caggatgatt ttatttccca caattcctta tgtaaaaatg
     4141 catttatata attcattaat ctattcctcc aatgattctg tatgttttaa atacagattt
     4201 tctaaaggtt cgtttatatt tttcatttct gaagaaaaaa ctttcttccc attttgaagt
     4261 atcattactt ttgtagatac cttggaaacg aaatccaaat tatggctgct aaaaataata
     4321 gttgtacctt catcttgtaa ttctttcatt gttttagtca aaatgtttaa actttctgga
     4381 tctataccat tggtaggttc atctaaaatt aatattctag gtttagtaat catggctgag
     4441 gctagtccta atcttttttt cattccatta gaccatgtat acgctttttc attacctcta
     4501 tttattaatt tgaatttctt tagtaatttt tgtgaatttt ctttaataat ttttaaaggt
     4561 agatttgata tgcgcccacg aaactctaaa tttctataag cagttaaatt ttcatatatt
     4621 ccattatttt cgggtaaaaa agaaatataa ttaaacccct tttttttcat attagtatca
     4681 gtaaatataa cttgtccatt actagggggt aacaacccca ttataattct aaacatagtt
     4741 gtttttccag caccgttatg tccaagcaat gcaaaaacat cacctgattt aatttcacac
     4801 gaaacatgat ccagtacttt ctgtttattg tatttaaatg ctatattttt tattttaagc
     4861 attactttcc tccactaaaa attaaatttt tattgtttca taacaaataa attataataa
     4921 tattatttta tttgtaaaaa atttaaatat tattataata taataactat tttagattat
     4981 ttatgataaa ctgtaaataa aaattatttt tgtattttat taatttgtat atttgataat
     5041 gttttaaaaa agggggcaat aaaattaaaa aaattttttt aactataata ttgatttttg
     5101 taattataac atctgttgta tataaatatg ttaataaaaa agttaaatta aatataaata
     5161 acataaagcg aatagatgtt ataaaattgc cagtgccacc gaagaaaaag gtagtaacaa
     5221 agaaagaaga tattgtggaa attataaatt ttataaattc aatacaatta ttagaagaaa
     5281 ttaatgatcc tgttaaaggg tggatttaca ccataaatat ttataataat tcaaataata
     5341 caaataatac aatagaattt ttaggagata aaataaacat ttataataaa tggtataaaa
     5401 ttaatgataa taatttggaa aaattgagaa aaatatataa agatttaaat tatgagcaag
     5461 cttcttttcc ttaattatta tttagatggt agataaatat atgtaacagt ataaataatt
     5521 gcttatttat tttataatta cttaactaat ctttaaatta aaagttatta cacaaatata
     5581 cacaggaaat ataagaagta cgtcaagtac tagtagagta tctattaatg atgaacttta
     5641 aaatcattta atataattat tttttatttg aaaaaataat tataaatagc ataaatatta
     5701 taatactgga gcagaaagag ataatagcgg attttattat tcccaaattt gtaatttttg
     5761 ataaaacaat gaaaattaca aatgtaaata aactacatgt aactgataaa actttagatt
     5821 tcattttatt cctcctataa ttgaattaat tggggggtta attattaata tttttcttat
     5881 tcattaagta aaatatatgt tcttgaattt catttcctaa ctaaaattat tatataataa
     5941 ctttattagt taaaaatagt aataattata aaaattaaat ttggaataat tttagcatga
     6001 aaacttagct ctatcaagga atttataaat aataacattt gttatatatg tatgtaataa
     6061 ctgtatttat aagcatcatt tgatgtatat aagaaaagaa caatctatat tttaagtaat
     6121 ataaaatttg acaattacgt tatagggggc actaatcaat gaatattgaa aaacttattg
     6181 aacaatttgg gaaaacatta ggtaaagtaa tttttaataa gaaggaagaa aaaagtaaat
     6241 attaatcaac ttagttcaac agacctattt agaataaatt ttaataaatt atttcataaa
     6301 aaaaattata ataaagcaga agatttaatt tttgatgagt taggaagaaa taattcccag
     6361 gaagtatatg aaatagcaat taaattttat aattcgttag caaataagag tgctaaagaa
     6421 ttaaatgaaa gtaattttcc taggaatgaa atttataaag gattacgaga tatacaaaaa
     6481 tttaagattg acttataaat tagtataatt tttttattag ttttattaat tgatttttat
     6541 atatttgatt gtaataaata ctattatagt aatattatta catttaacta agttgagata
     6601 aatctatgtt catataactt aacagaacaa attcactaag gatggaatag aaaataaact
     6661 tggatataat aaagaaaaag caagaaatga aggaactaaa ggatttaaat tatcaaaaga
     6721 gagagaaagt aataaaatca ataaataata aaggagttaa gcaaactgat atacaaagta
     6781 gattacatag acaaattgac ttggaaggac agagcaaagc agtatgcagt acagttagga
     6841 atatcagtag ggacaattct tttagtgtta ggagcatatc atctgataac ttatttgata
     6901 aaataattaa agatgttaca acagatattg aaaaatcatc aaaagaagaa taagaaattc
     6961 aattagaatt aaaaaataaa aaaatatcta aattaaagaa taggtgtaag gatttagata
     7021 tagaaagata aaaaaactag cattttaaca tgctagtttt ctaattataa ctaaaaataa
     7081 tggagtaaaa atggagcaaa acagagtaaa aatagagtaa ttttagagta aaaatggagt
     7141 aaaaaaaact tgaatatgat atcatttttt ctagtgtttt ttatcttgaa atatagttgg
     7201 cacagccaac ttagaacttt gcggatagca tgtgatatca tatttttctt atgctctttt
     7261 ttatgtgata ttttaaaaaa aattaattct tataacatta aattcaattg cattattata
     7321 atgtatttaa tgcgatttat taccatttat gatataattt aagaaaaaat tatatttttt
     7381 attttataga atgaaaataa atttattgag gaggtttaaa ggggatgatt gaagttaaaa
     7441 atttagctaa gatatttaag aatggagtta cagcagtaaa taatataaat ttcaaagtaa
     7501 ctgatggaga aatacttggc ttacttggag aaaatggagc aggtaaaaca acaaccctta
     7561 gaatgcttgc taccatgctt aaaatcacag agggacaggc attgataaat ggtcatgatg
     7621 taagtaaaga agcggataaa gtaaggggac aaataggtat tctgtttggt ggtgaagttg
     7681 gcctttatga cagacttaca gcaagggaga atataaaata ttttgcagaa cttaatggca
     7741 tgtctgaaga agaaactaat aaaagtatag aggaacttgc aaaaaattta gatatgacag
     7801 aatatcttga tagaagagtt ggaaagtttt caagaggtat gaaacaaaaa gtggctattg
     7861 caagatctat agtacataat ccatctgttg ttttgtttga tgagccaact ataggattag
     7921 atgtaacctc tgcaaaaatt gtacaagatt tcatattaaa atgtaaaagt gatggaagaa
     7981 ctattatatt ctcaagtcac acaataccag aagtagaaaa gctatgtgat agaattgtta
     8041 taattcataa aggtaagata gttgaagaag gaaagcttaa agaacttgaa gaaaaatata
     8101 ataatagcat agaagaaata tttgtaaatt taatagcaaa gtaaagaagg tgaaaatatg
     8161 aaaaatgtag taggagtagt attaaaaaaa gaacttttag atttatttag agacaaaaaa
     8221 actctaatat taagtatatt gattccaata attcttttac ctataatgtc ttttggtatt
     8281 ggtaaagttg caaaatcaga tagtgataag gttcaaaaca atcttaaaat agtcatagta
     8341 gaccaaggag agagtagttt ttctaaattt ataaaatctc ataaaaatgt taatataata
     8401 aattctaaaa acattgacaa agatataaaa gagggagacg tatatgtaca gattaaaatc
     8461 ccaaaaggat ttgatgagaa tatatcaaag aattttaatg aaaaaataga attaaaatat
     8521 gataactcaa gtaatgatgc aatgacagct gtatcaatga taaaaaatta tatagaggaa
     8581 tattcaaaac aaatagtctc aaaacgactt gaaaagagta atatagatca atcaatatta
     8641 actccaatta atattgtaga taatgtggtt ggaaataaag aagagggttt gggaaaaata
     8701 atggctgcta tgcttattcc tttacttttg atgctctata gtgcaacaag tacaattgga
     8761 gcatcagtgg atctaggtgc aggagagaaa gaaagaggaa cacttgaacc acttcttaca
     8821 acaaaagctg gaagaacctc tttacttgtt ggaaaatttc ttacaataac aataatggga
     8881 atattaatgt cctgtgcata tttgattgga ataataatta caatgaaaca gcctaatgga
     8941 atgtttggaa atgcaggact aaacttagga acagctactt tagttcttat tatgatttta
     9001 cctatcttat atacaatggt atttggagca cttcaacttg ccattagtat ttatgcaaga
     9061 tcgtttaaag aagcgcaaac ttatttaagt ccaataactg ttatagctat agttttaatt
     9121 tatatggtta tgatgaaaga ccctaaaagc attccaatag tttattttaa tataccactt
     9181 acaaatggag tatgcgttat gaaggaattt ttagcaggaa tttataatta tactcacata
     9241 gcaataactt ttggatggat agtattttat atatttctgg ctatcttatt tgcaagatac
     9301 atgttctcaa aagaagaagt tatatttaga acataaaata atataaaatt ttagaagtgt
     9361 gttatacgag gtacaagtca atgaatattg aaaaacttat tgaagagttt gggaaaacat
     9421 taggtaaagt aatttttaat aagaaggaag aaaaaagtga aaaagtaaat attaatcaac
     9481 ttagttcaac agacatattt aaaataaatt ttaataaatt atttcatgaa ggaaattata
     9541 ataaagcaga agatttaatt tttgatgagt tagaaagaaa taattcgcca gaagtatatg
     9601 aagtagcaat taaattttat aatttgttag caaataagag tgataaagaa ttaaatgaaa
     9661 gtaattttcc aagaaatgaa atttataaag gattgcatga tatacaaaaa tttaagattg
     9721 atttatagat tagtataatt ttttataggt attaaaagtg cttaacaatt atattgattt
     9781 ttactaaaat aactagataa gtttatgtaa aaacaaattt atctagttat ttttacataa
     9841 atattttact tatttataca aaatttaaaa taatatcatt gacagttaaa ctatattata
     9901 atatactatt tttaattaaa tatcatattt ttgtaaatta taataaaaaa atgtattaac
     9961 tttaataaaa atataataac gaaattggtg gtgagagaat atgcatttat tctttgatac
    10021 agtacccaaa gaaaatataa tgtttccaga ttttttttca ttgtatttag aaaaatttga
    10081 ttataaattt aatgttcttt ataagaataa aaataaaaat gttagcttta atggaatata
    10141 ttcttattta tatacaagtt tattaaattg ttctattaga actttaataa gagaattaca
    10201 taattataaa gctaaaaatt tattatcagg agatacatct aaggaaagat ttttatcttt
    10261 tgaaaaaata actaaaaata aatcttttat tacatatctt taccaagaat atccagagtt
    10321 aaaatctctt ttagaacaaa aaataacaca aacagcgtta tatgtatgtg aaattatgaa
    10381 taattttgaa aaagataaat tagaacttca aaaaaatttt caaaaaaatt ttgagaaaat
    10441 aatagatatt catctgggta aaggggatac tcataatgga ggaaagtctg ttgcaattat
    10501 agagtctaat tgtggaaaaa ttgtatacaa gcctcataat ctttcacctg atatagtttt
    10561 tgaaaatata attagttggg taaatttgaa aaatatatta aagtgtaaat taaactcatt
    10621 aaaagttatt gattatgata attatggctg gcaagagttt gttagatacg aggaatgtga
    10681 aaattatata gaagtacaaa attattatta tagatcgggt tgttttttag caatatttta
    10741 tactttaggt acaaatgata ttcattttga aaatgttatt gttaatggag aatacccatg
    10801 ttttattgat ttagaaacat tggttggtat aaatagaccg ggacaaatat cttcagtttt
    10861 agcaacagga tttattccta ataaatcctt aaataattta tttgatatag atttaagcgg
    10921 tttatgtggg aaaatgcaaa catcatcaaa acttacaaca atagcaataa ctaatcctaa
    10981 aacggatgaa atgatagtag aaagccaacc tgcaaaaata tattgcaata ataatatagt
    11041 taagttaaat aataaaagtg taaaaattga aaattataca agtgttttta taactggatt
    11101 taaagatact ttagagttaa taattaataa taaaattgaa tatattagct taatagaaaa
    11161 agagtttaat aaatttcaaa agtttagaca agtaattagg catactcaag tttattctaa
    11221 atttttaata gcagcttcac atccagatta tttaaaaagc gaaaataaac ggatggaatt
    11281 atttaaaaga ctttataatg gatgtgaaaa tgaaagagaa cataaaagaa tttctaatga
    11341 aattaatact ttatttaaat gggatattcc atattattat tgtaattatg attcaaaaga
    11401 tttattttca gataatataa caatatgtaa aaattatttt caatcgactg taaaaaaatc
    11461 tttatataac aaaattgaaa gaataaatag tgaaattgaa aattttcaaa tagatgtcat
    11521 taaaaaatct ttatttaccg tatatgaaga tcaattcatg aataacaaat ttaatagagt
    11581 aaaaatttat aataataata ataaagtatc acatgaagaa attataatga aaatttcaaa
    11641 cgatatatct tctaatattt tagaattaga agataataat aaagtatcat ttttgattaa
    11701 tataattcag aataatcaag ttttactttc accaataaat tttaatttat atgaaggtgg
    11761 aggaattata tggttatttg cttctttagg aaaactattt aataataagt attatgaaaa
    11821 aatgtcaatt aaattattgg aatcttctat attaacatat gagtattatg ataaaaaaca
    11881 aaataatatt gaaaaaattt cagcattttt tggaatagga tcacttatgt atttatatta
    11941 taatatatcc gttctttata ataataagga atattattat aaatttatag atgttgcaaa
    12001 taagatactt gaatataatt gtgatcattt ggaagaatct aacaattcat tagattatga
    12061 ttttgtttgt ggaatttctg gtatattagt attgtctgtt aagatttatt taaaagaaaa
    12121 aaattattta atgaaaaaaa ttattgatag atattctgat tatttattca aatttattaa
    12181 taataatatt aaggatttaa ataaaattgg gttagctcat ggcttatcag gatattcatt
    12241 agctttaatt atgatttact atgcaaaaca ggataaggta tatttagatt tagctactaa
    12301 acttataaat aaagaaaatt taatttattc aaatgatgaa aatgtagata agattaaaac
    12361 gtcatggtgt aatggacaaa cagggatggc attagtccgt agtgaaatac taaaaattaa
    12421 ttatgataaa aatatatcaa atgatattct taaatatctg agaaatatgg taactgatgg
    12481 attttacaac atgaatagta tgtgtttatg tcatggaatt tatggaaata tagagattgt
    12541 aaataaaatt attaataata taaatcaaac taataaaata attactcatg atgaagtaac
    12601 cgagttcgaa acaaagctaa ttagtaatat aaacgatatt cagttaggtt ttaaaaataa
    12661 ttttatgtta gatacgttta tggctggaag tagtggtatt gcatatgcaa agttaagact
    12721 tttatatcct gaaatgccat caatcttatc tttagatata ataaaagatt tttaaaatta
    12781 gaatgtaaac aagctatagt tgaatagatt atttttttaa taaaatttat aatctatgag
    12841 gtgaaaatat gaaaaaatta gtttcaataa ttggtagcca taaaggttat aattctaaaa
    12901 catatgatat tgcatataaa gtttcagaag gattaaaaaa taaaaataat aatatttcta
    12961 gtgaattttt tatcttatct gaactagaca taaataaatg cacagggtgt ttaggatgtt
    13021 ttactaaatg tagttcatgt gtaattttta atgatagtat gagtatatta gaaaagtcaa
    13081 tgtttgatgc tgatattatt atatttggct cacctgtata tgcacataat attactgggg
    13141 atatgaaaat ttttattgat agattgtgtc atttacttca tataatgggg ttatgcggga
    13201 aatatggagt aacagtttct acttcttcat caaatggaaa tacatttgta gataattatt
    13261 tatttaaaat tatggagtat ttaggaatac gtgttgttga tcaaatttct tatgtttcat
    13321 atcataaatt tgaagacaag catattacta aatgtgttga taaaattgat ggaattttaa
    13381 ataataaaat tttattacca cctagtgaat ttcaagaaca aatttttaat atttataaaa
    13441 aaatttattt taaaagttat gaagaaagta ttataaataa aaatgttgta aaaaatcaag
    13501 aagcatgtta ttggcatgat aatggatact ttaattataa ttcgtttgaa gaattgttta
    13561 atataatgaa aaataaataa aattaatgat attaaccttt ggttttatgt atgtttaaac
    13621 aaaaggttaa cataaatcat aaattaagaa aggtggaaaa aagatgacaa aaaattttga
    13681 tccagcagga atagttgatt taaaagaact tgatgagctt gctcatattg gaggttctga
    13741 tgttgaagct caaacaactc caacaattgc atcagtatta gtatctgtta taagtgttga
    13801 attaacagta tcagcagcca ctgttacagc tcaatgtttg taataaaaag taatcaagcc
    13861 accatatgag gtggcttgat taaattatac cttatttcaa aattattttg tctaaatatt
    13921 aatttatgat gtattattaa gtatctatat ttattttagt ttggaaatag ttataaatat
    13981 tggaggtaaa gctatagtga gtagcttaaa taataaatat gaaagatgga gatgggatat
    14041 tgataaagta acaaataata gaaaaagtta taaaattcaa caaggaaatc atacggttaa
    14101 agtagcaatt atagatagtg gtatagataa aaatcatcca gatttaaaaa ataatattat
    14161 tagtaataaa agttttatac cccaaaataa ctctcttgaa gatacttttg ggcatggaac
    14221 aatggtagct ggggaaatag cagctaatgg taatgtaaaa ggtgttgcac ctaggattgg
    14281 tatagcatct tataaagttt ttgatggtac taattgtgaa tcgatatggg tgataaatgc
    14341 tataattgaa gctgcaaatg atgggatgga tgtaattaat ttaagtttgg gaacctataa
    14401 atcaatatta gataaaaaag atatatatat attgcttgct tacaaaaaag ctatcgaata
    14461 tgcacagtca aaaaattgca tagttataac agcttcagga acaagactta aaggagtaga
    14521 tatatcgaat ccttttaagt tatcaaaaaa tttaggaaat aaaaatgatt taaaaatata
    14581 tttaccaggg gggttaccta atgtaataac agtttctgct acaaataaaa atgatgaact
    14641 tgcatactat tctaattatg gtaatactgt tcaaatagct gctccagcag gagattatgg
    14701 accaaattat caaacacaaa aaattacgaa ttttaaatat atgacattag taacataccc
    14761 tactggttta ccccaatctc aattaagttt atcgatggga tttaaaaaag ggtatgaatt
    14821 tattgaaggc ggaacaagta ttgcagcggc aaaagtttca gcagcagcag cattgttaat
    14881 tgcacaatat aatgaaacat atggatttaa accatcaaga ttgaaagtag aaaagttatt
    14941 atatgatggt gtaactccag cagttaaaag agatactgaa atatattttg gaaaaggaat
    15001 tttaaatgtt gaaaattctt tgaatttaat taaaaactaa atttctagca taacaagttt
    15061 attacaatta tattttttat aataatggtt attatgtatt attatatttc taaaaattga
    15121 tttgagttaa atataactaa ataataatat aatgtagatt taaaacaaag tttaatcgtt
    15181 ttgaataaag tttaatcatt cgtatttttc tctatataga tagaaatgct ttaattttaa
    15241 aatgaagtac ttctatttat tttaaaatat cacgaactat tactatatat taaaatttaa
    15301 tattcaatag actttaaagt tttgatcaaa ctttgtttaa aaatattgaa aatacttttg
    15361 agattttaag ccatttacat gtattgtttt gattgaactt tatttaaaac ctacatataa
    15421 aataaatgta ttatagaatt aatcaatgta tattttaaat gtaacacact ggagattttg
    15481 taacattgga gaaaaatagg gtataagtat tgagatgtaa gtacttgtag cctatttttt
    15541 tattattcta ctgtgagagt atttaaggga atgtaacata tcttatctat aaataccatt
    15601 caatgtatta taatgtatgt aagaggtgat aaaattcaat aagatgaaag tggtttaaat
    15661 gatgattaaa gaatggttaa aacaaggcag agaaattttc atactataaa taattatatt
    15721 ttctattaaa atataatcta cattttgtta taattttata aaggggggca atcacatgaa
    15781 aaaaacacta aaaaaaataa ctataatctg catttcttta attgtcacat ttctaattca
    15841 tagagaaatt acaacggaac taatttataa ttatatattt attactaata ataacattga
    15901 aacaatcgta catataggag caatattaat tcaatttatg tgtttttatt taataataag
    15961 ggaaataatt aatcagagag tggataaact tttctataaa actctatggt tttgctattt
    16021 catagtatta tcttttttac tctttggtag agctagggga tttcaaggat ttcaagaatg
    16081 taatactaat cccttacatt tcatagaaaa ctttgaatca aataaagatt ctttaataat
    16141 tacaatcatg aatatattat tttttatacc tattggatat ttattcagac acaaaagata
    16201 tataatatct attttaataa tatgtttatc aatagaatca atacaatata ttttttcatt
    16261 aggtattttt gatatttgtg atattatatt taatataatt ggttttttta taggatattt
    16321 aagttgtaaa aataaaaatt tcaattctat aacagtttca taaatataat aacatataaa
    16381 actgttattt ttgcaatata aaaaaggagt tttttatatt gcaaaaattt aattataata
    16441 aattctaaat gtaattatac tcatcgtaag ctactctaaa ccatttttct tttcctaaat
    16501 acaatccaaa taatcatttg cacaaaacgt tttaaaattg attacagaga gctctaagct
    16561 gatatattaa ctatagttac ctacaaaata attaaaaata cctttagtta ttctcgtttt
    16621 agaaatatct tttaatcaaa aggcaatcat ctacggaatt tacctattta aattaaagtg
    16681 agttaaggtg caatacgtat ttaaaaccaa gtttgcttgg cttgtttttt taaccaaata
    16741 aactctttcc atagcaaggc tttatttaaa gttaaaaaat tttaaataca tcagggactg
    16801 catcttaact caacacataa tttattctat ttctaaaaca tttatatatt gataaataaa
    16861 gggcttattt gtttttatat acacatattt ttttaaaatt agtattgtat ataatttcat
    16921 ataatctttg tatatataaa ttatatcaaa aatattctaa ggaaatcaat aaatataagt
    16981 atctttaaca atatagtatt cattatcatt tacataagta ttcttaatta attcagtgtc
    17041 tatgccactc tttgagttgt ggtaatcaac tctttatcct gcgctatgcg aattttaatt
    17101 aaaagttaag aaataatcaa tttaaaatta tagaatctaa agaaatatgt gcaaatgaaa
    17161 taaaagtggg cagacctaaa aaaacaataa gggcagtaag cacactgtaa tttttaatga
    17221 tgatgtttgg aggatttaag aataaaaagt ataaaggagc atacaactgc atctgaaatt
    17281 cttgctataa actttttata taaataaaat ttatttaacc aactaaacca atggaggtat
    17341 tgggaggctc cattggtggg ggcggtagtt tttgggtagg gttttaggga aatttctatt
    17401 ccctaacagg ggtggacgga ggtcaccgtc cataatccta ctttggaact ttggagttga
    17461 gtacaacttc ttcttttata ttttttacat atcaatctaa aaattgaaat aataaaattc
    17521 ttttgttttt tgttcattta attctatgct ttcctctgtt ttattccaac ctaataattt
    17581 tctttctaaa tcaacaaaat catattgtct ttgttcaaag tcattaaatt tatccacttt
    17641 tgtttttcct ataggctctt tataatctct ttttaaagcc tctataatcc aacccactaa
    17701 attattaata ttattagttt gttttgctat ttgatacttt tctttaatta attcaatatt
    17761 tctttttgat acatcaaata tttgtttagc ttgtaaactt gatatttctt catgaaaaat
    17821 tgatttaact tgctctatgt aatttgtttc ttcaaaagtg gcacatattt cttccttagc
    17881 tatattattt tgcttcttag attttatata aaatctaaga gcagttacct ttcttccagt
    17941 ttttatttct tcaaactcaa aacttatgtc tgttttttct tttaattctt tttgagttga
    18001 ttttagtaat ttttgtttaa aattagcata taaaggatat acattttctg cttttaaaag
    18061 ttttcttaaa tcttctattt ctaattcaat atatccctgt tttttaaact cattacattt
    18121 taaaatctca tatattctag gagaatattt acttttcata gttaatatgt tttctaattt
    18181 atattgagta aacatactat taagtttcaa catataaggc tttagctttg gtgaaaattc
    18241 taattcaact attccacttc cttttttata agttgcagaa cttaaccaag cagtttgaat
    18301 taaagtatca ccttcattaa tttcaaatac ctttttcatt aattctttag ttattttagg
    18361 tatttctata tattttgttt tagtattaac atttattaat ttcataaaat ctgaaatcat
    18421 aaatttataa ggtttaaaat cctca
//
