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Overview
1.1
1.2
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1.4

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP075979.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | RRE-containing | 590,841 | 609,460 |
Region 1.2 | cyclic-lactone-autoinducer | 1,088,282 | 1,099,897 |
Region 1.3 | cyclic-lactone-autoinducer | 2,030,346 | 2,051,145 |
Region 1.4 | ranthipeptide | 2,440,643 | 2,462,226 |

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | RRE-containing | 590,841 | 609,460 |
Region 1.2 | cyclic-lactone-autoinducer | 1,088,282 | 1,099,897 |
Region 1.3 | cyclic-lactone-autoinducer | 2,030,346 | 2,051,145 |
Region 1.4 | ranthipeptide | 2,440,643 | 2,462,226 |

No secondary metabolite regions were found in these records:
  NZ_CP075980.1

Compact view
NZ_CP075979.1 - Region 1 - RRE-containing
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 590,841 - 609,460 nt. (total: 18,620 nt) Show pHMM detection rules used
RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RRE-containing | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000775.1 |  | 0.19 | Saccharide | lipopolysaccharide | Legionella pneumophila
BGC0001526.1 |  | 0.18 | Other | bartolosides E, bartolosides F, bartolosides G, bartolosides H, bartolosides I, bartolosides J, bartolosides K | Synechocystis salina LEGE 06099
BGC0001356.1 |  | 0.17 | RiPP | paeninodin | Paenibacillus dendritiformis C454
BGC0001525.1 |  | 0.17 | Other | bartoloside 2, bartoloside 3, bartoloside 4 | Synechocystis salina LEGE 06155
BGC0000744.1 |  | 0.17 | Saccharide | capsular polysaccharide | Streptococcus agalactiae
BGC0000748.1 |  | 0.17 | Saccharide | capsular polysaccharide | Streptococcus agalactiae
BGC0000740.1 |  | 0.17 | Saccharide | capsular polysaccharide | Streptococcus agalactiae
BGC0000745.1 |  | 0.17 | Saccharide | capsular polysaccharide | Streptococcus agalactiae
BGC0000747.1 |  | 0.17 | Saccharide | capsular polysaccharide | Streptococcus agalactiae
BGC0000746.1 |  | 0.17 | Saccharide | capsular polysaccharide | Streptococcus agalactiae

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000775.1 |  | 0.51 | Saccharide | lipopolysaccharide | Legionella pneumophila
BGC0001526.1 |  | 0.49 | Other | bartolosides E, bartolosides F, bartolosides G, bartolosides H, bartolosides I, bartolosides J, bartolosides K | Synechocystis salina LEGE 06099
BGC0001356.1 |  | 0.49 | RiPP | paeninodin | Paenibacillus dendritiformis C454
BGC0001525.1 |  | 0.48 | Other | bartoloside 2, bartoloside 3, bartoloside 4 | Synechocystis salina LEGE 06155
BGC0000744.1 |  | 0.48 | Saccharide | capsular polysaccharide | Streptococcus agalactiae
BGC0000748.1 |  | 0.48 | Saccharide | capsular polysaccharide | Streptococcus agalactiae
BGC0000740.1 |  | 0.48 | Saccharide | capsular polysaccharide | Streptococcus agalactiae
BGC0000745.1 |  | 0.48 | Saccharide | capsular polysaccharide | Streptococcus agalactiae
BGC0000747.1 |  | 0.48 | Saccharide | capsular polysaccharide | Streptococcus agalactiae
BGC0000746.1 |  | 0.48 | Saccharide | capsular polysaccharide | Streptococcus agalactiae

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP075979.1 - Region 2 - cyclic-lactone-autoinducer
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,088,282 - 1,099,897 nt. (total: 11,616 nt) Show pHMM detection rules used
cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

No matches found.

No matches found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP075979.1 - Region 3 - cyclic-lactone-autoinducer
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,030,346 - 2,051,145 nt. (total: 20,800 nt) Show pHMM detection rules used
cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | cyclic-lactone-autoinducer | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001586.1 |  | 0.15 | Saccharide | EPS273 | Pseudomonas stutzeri
BGC0000648.1 |  | 0.15 | Terpene | carotenoid | Myxococcus xanthus
BGC0000645.1 |  | 0.11 | Terpene | carotenoid | Halobacillus halophilus DSM 2266
BGC0001686.1 |  | 0.08 | NRP | N-octanoyl-Met-Phe-H | Clostridium sp. CAG:567
BGC0001053.1 |  | 0.05 | NRP, Polyketide | tubulysin A | Archangium disciforme

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001586.1 |  | 0.46 | Saccharide | EPS273 | Pseudomonas stutzeri
BGC0000648.1 |  | 0.46 | Terpene | carotenoid | Myxococcus xanthus
BGC0000645.1 |  | 0.38 | Terpene | carotenoid | Halobacillus halophilus DSM 2266
BGC0001686.1 |  | 0.31 | NRP | N-octanoyl-Met-Phe-H | Clostridium sp. CAG:567
BGC0001053.1 |  | 0.23 | NRP, Polyketide | tubulysin A | Archangium disciforme

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP075979.1 - Region 4 - ranthipeptide
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,440,643 - 2,462,226 nt. (total: 21,584 nt) Show pHMM detection rules used
ranthipeptide: (TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085 or SPASM)) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716 or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or YcaO or TIGR03882)))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | ranthipeptide | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001891.1 |  | 0.22 | Other | closthioamide | Ruminiclostridium cellulolyticum H10
BGC0001387.1 |  | 0.17 | Other | nucleocidin | Streptomyces calvus
BGC0000599.1 |  | 0.17 | RiPP | thuricin CD α, thuricin CD β | Bacillus thuringiensis
BGC0001591.1 |  | 0.09 | Other | fatty acid enol ester | uncultured bacterium CSLC2
BGC0001688.1 |  | 0.09 | Other | N-tetradecanoyl tyrosine | uncultured bacterium CSLC2
BGC0001155.1 |  | 0.09 | RiPP | GE2270 | Planobispora rosea
BGC0000027.1 |  | 0.08 | Polyketide | ankaflavin, monascin, rubropunctatine, monascorubrin | Monascus pilosus
BGC0001089.1 |  | 0.05 | Polyketide, NRP | bacillaene | Bacillus velezensis FZB42
BGC0000413.1 |  | 0.03 | NRP | pyoverdin | Pseudomonas protegens Pf-5

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001891.1 |  | 0.55 | Other | closthioamide | Ruminiclostridium cellulolyticum H10
BGC0001387.1 |  | 0.49 | Other | nucleocidin | Streptomyces calvus
BGC0000599.1 |  | 0.49 | RiPP | thuricin CD α, thuricin CD β | Bacillus thuringiensis
BGC0001591.1 |  | 0.33 | Other | fatty acid enol ester | uncultured bacterium CSLC2
BGC0001688.1 |  | 0.33 | Other | N-tetradecanoyl tyrosine | uncultured bacterium CSLC2
BGC0001155.1 |  | 0.32 | RiPP | GE2270 | Planobispora rosea
BGC0000027.1 |  | 0.30 | Polyketide | ankaflavin, monascin, rubropunctatine, monascorubrin | Monascus pilosus
BGC0001089.1 |  | 0.23 | Polyketide, NRP | bacillaene | Bacillus velezensis FZB42
BGC0000413.1 |  | 0.17 | NRP | pyoverdin | Pseudomonas protegens Pf-5

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names