GCF_001856695.1_ASM185669v1_genomic - 11 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP013019.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	RiPP-like	206,603	218,633
Region 2	cyclic-lactone-autoinducer	484,464	503,740	thurincin H	RiPP	20%
Region 3	cyclic-lactone-autoinducer	1,387,207	1,407,452
Region 4	RRE-containing,cyclic-lactone-autoinducer	2,121,424	2,147,979
Region 5	cyclic-lactone-autoinducer	2,195,011	2,214,719
Region 6	ranthipeptide	2,382,073	2,403,693
Region 7	cyclic-lactone-autoinducer	2,670,330	2,688,177
Region 8	cyclic-lactone-autoinducer	2,732,238	2,751,830
Region 9	cyclic-lactone-autoinducer	2,996,968	3,014,830
Region 10	T1PKS,NRPS-like,NRPS	3,125,445	3,181,971
Region 11	cyclic-lactone-autoinducer	3,555,093	3,575,746

NZ_CP013019.1 - Region 1 - RiPP-like

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Location: 206,603 - 218,633 nt. (total: 12,031 nt) Show pHMM detection rules used

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000558.1	0.24	RiPP	sublancin 168	Bacillus subtilis subsp. subtilis str. 168
BGC0001862.1	0.22	RiPP	geocillicin	Aeribacillus pallidus
BGC0001930.1	0.22	RiPP	pallidocin	Aeribacillus pallidus
BGC0001863.1	0.22	RiPP, Terpene	bacillicn CER074	Bacillus mycoides
BGC0001861.1	0.21	RiPP	bacillicin BAG2O	Bacillus cereus BAG2O-1
BGC0000554.1	0.20	RiPP	SRO15-3108	Streptomyces filamentosus NRRL 15998
BGC0000484.1	0.20	RiPP	glycocin F	Lactobacillus plantarum
BGC0000617.1	0.20	RiPP	coagulin	Bacillus coagulans
BGC0000500.1	0.19	RiPP	carnolysin A1, carnolysin A2	Carnobacterium maltaromaticum
BGC0000504.1	0.19	RiPP	cytolysin ClyLl, cytolysin ClyLs	Plasmid pAD1

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000558.1	0.58	RiPP	sublancin 168	Bacillus subtilis subsp. subtilis str. 168
BGC0001862.1	0.55	RiPP	geocillicin	Aeribacillus pallidus
BGC0001930.1	0.55	RiPP	pallidocin	Aeribacillus pallidus
BGC0001863.1	0.55	RiPP, Terpene	bacillicn CER074	Bacillus mycoides
BGC0001861.1	0.54	RiPP	bacillicin BAG2O	Bacillus cereus BAG2O-1
BGC0000554.1	0.53	RiPP	SRO15-3108	Streptomyces filamentosus NRRL 15998
BGC0000484.1	0.53	RiPP	glycocin F	Lactobacillus plantarum
BGC0000617.1	0.52	RiPP	coagulin	Bacillus coagulans
BGC0000500.1	0.51	RiPP	carnolysin A1, carnolysin A2	Carnobacterium maltaromaticum
BGC0000504.1	0.51	RiPP	cytolysin ClyLl, cytolysin ClyLs	Plasmid pAD1

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

Selected features only

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NZ_CP013019.1 - Region 2 - cyclic-lactone-autoinducer

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Location: 484,464 - 503,740 nt. (total: 19,277 nt) Show pHMM detection rules used

cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000486.1	0.17	RiPP	butyrivibriocin AR10	Butyrivibrio fibrisolvens
BGC0000616.1	0.16	RiPP	amylocyclicin	Bacillus velezensis FZB42
BGC0001743.1	0.16	RiPP	plantaricyclin	Lactobacillus plantarum
BGC0001222.1	0.16	RiPP	acidocin B	Lactobacillus acidophilus
BGC0000491.1	0.16	RiPP	gassericin A	Lactobacillus gasseri
BGC0000494.1	0.16	RiPP	uberolysin	Streptococcus uberis
BGC0001863.1	0.16	RiPP, Terpene	bacillicn CER074	Bacillus mycoides
BGC0001862.1	0.15	RiPP	geocillicin	Aeribacillus pallidus
BGC0001930.1	0.15	RiPP	pallidocin	Aeribacillus pallidus
BGC0000600.1	0.15	RiPP	thurincin H	Bacillus thuringiensis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000486.1	0.48	RiPP	butyrivibriocin AR10	Butyrivibrio fibrisolvens
BGC0000616.1	0.47	RiPP	amylocyclicin	Bacillus velezensis FZB42
BGC0001743.1	0.46	RiPP	plantaricyclin	Lactobacillus plantarum
BGC0001222.1	0.46	RiPP	acidocin B	Lactobacillus acidophilus
BGC0000491.1	0.46	RiPP	gassericin A	Lactobacillus gasseri
BGC0000494.1	0.46	RiPP	uberolysin	Streptococcus uberis
BGC0001863.1	0.46	RiPP, Terpene	bacillicn CER074	Bacillus mycoides
BGC0001862.1	0.46	RiPP	geocillicin	Aeribacillus pallidus
BGC0001930.1	0.46	RiPP	pallidocin	Aeribacillus pallidus
BGC0000600.1	0.45	RiPP	thurincin H	Bacillus thuringiensis

Similar known gene clusters

Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

Selected features only

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NZ_CP013019.1 - Region 3 - cyclic-lactone-autoinducer

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Location: 1,387,207 - 1,407,452 nt. (total: 20,246 nt) Show pHMM detection rules used

cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000494.1	0.16	RiPP	uberolysin	Streptococcus uberis
BGC0000486.1	0.16	RiPP	butyrivibriocin AR10	Butyrivibrio fibrisolvens
BGC0001861.1	0.15	RiPP	bacillicin BAG2O	Bacillus cereus BAG2O-1
BGC0001206.1	0.13	Other	indolmycin	Streptomyces griseus subsp. griseus
BGC0000523.1	0.13	RiPP	lactocin S	Lactobacillus sakei
BGC0001407.1	0.13	RiPP	bicereucin	Bacillus cereus SJ1
BGC0000540.1	0.13	RiPP	paenibacillin	Paenibacillus polymyxa OSY-DF
BGC0000555.1	0.12	RiPP	staphylococcin C55 α, staphylococcin C55 β	Staphylococcus aureus
BGC0000542.1	0.10	RiPP	paenicidin B	Paenibacillus terrae
BGC0000541.1	0.10	RiPP	paenicidin A	Paenibacillus polymyxa

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000494.1	0.47	RiPP	uberolysin	Streptococcus uberis
BGC0000486.1	0.46	RiPP	butyrivibriocin AR10	Butyrivibrio fibrisolvens
BGC0001861.1	0.45	RiPP	bacillicin BAG2O	Bacillus cereus BAG2O-1
BGC0001206.1	0.41	Other	indolmycin	Streptomyces griseus subsp. griseus
BGC0000523.1	0.41	RiPP	lactocin S	Lactobacillus sakei
BGC0001407.1	0.41	RiPP	bicereucin	Bacillus cereus SJ1
BGC0000540.1	0.41	RiPP	paenibacillin	Paenibacillus polymyxa OSY-DF
BGC0000555.1	0.39	RiPP	staphylococcin C55 α, staphylococcin C55 β	Staphylococcus aureus
BGC0000542.1	0.36	RiPP	paenicidin B	Paenibacillus terrae
BGC0000541.1	0.35	RiPP	paenicidin A	Paenibacillus polymyxa

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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NZ_CP013019.1 - Region 4 - RRE-containing,cyclic-lactone-autoinducer

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Location: 2,121,424 - 2,147,979 nt. (total: 26,556 nt) Show pHMM detection rules used

RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])
cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000928.1	0.29	Other	T3 toxin	Cylindrospermopsis raciborskii T3
BGC0000188.1	0.29	Alkaloid	saxitoxin, neosaxitoxin, decarbamoylsaxitoxin, gonyautoxin 3, gonyautoxin 2	Cylindrospermopsis raciborskii T3
BGC0000599.1	0.29	RiPP	thuricin CD α, thuricin CD β	Bacillus thuringiensis
BGC0001521.1	0.29	NRP	auriculamide	Herpetosiphon aurantiacus DSM 785
BGC0000780.1	0.28	Saccharide	O&K-antigen	Vibrio parahaemolyticus
BGC0000557.1	0.27	RiPP	streptococcin A-FF22	Streptococcus pyogenes
BGC0000540.1	0.25	RiPP	paenibacillin	Paenibacillus polymyxa OSY-DF
BGC0000842.1	0.24	Other (Non-NRP beta-lactam)	carbapenem MM4550	Streptomyces argenteolus
BGC0000515.1	0.24	RiPP	geobacillin I	Geobacillus thermodenitrificans NG80-2
BGC0000506.1	0.24	RiPP	entianin	Bacillus subtilis subsp. spizizenii

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000571.1	0.48	RiPP	burhizin	Paraburkholderia rhizoxinica HKI 454
BGC0000557.1	0.47	RiPP	streptococcin A-FF22	Streptococcus pyogenes
BGC0001289.1	0.47	RiPP	penisin	Paenibacillus ehimensis
BGC0000599.1	0.47	RiPP	thuricin CD α, thuricin CD β	Bacillus thuringiensis
BGC0000486.1	0.46	RiPP	butyrivibriocin AR10	Butyrivibrio fibrisolvens
BGC0000539.1	0.46	RiPP	nukacin ISK-1	Staphylococcus warneri
BGC0000538.1	0.46	RiPP	nisin Z	Lactococcus lactis
BGC0001407.1	0.46	RiPP	bicereucin	Bacillus cereus SJ1
BGC0000541.1	0.46	RiPP	paenicidin A	Paenibacillus polymyxa
BGC0000616.1	0.46	RiPP	amylocyclicin	Bacillus velezensis FZB42

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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NZ_CP013019.1 - Region 5 - cyclic-lactone-autoinducer

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Location: 2,195,011 - 2,214,719 nt. (total: 19,709 nt) Show pHMM detection rules used

cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000887.1	0.14	Alkaloid	saxitoxin, gonyautoxin 2, gonyautoxin 3, toxin C2, toxin C3, gonyautoxin 5, decarbamoylsaxitoxin, decarbamoylgonyautoxin 2, decarbamoylgonyautoxin 3	Dolichospermum circinale AWQC131C
BGC0000472.1	0.11	RiPP	anacyclamide A10	Anabaena sp. 90
BGC0000565.1	0.10	RiPP	goadsporin	Streptomyces sp. TP-A0584
BGC0001591.1	0.05	Other	fatty acid enol ester	uncultured bacterium CSLC2
BGC0001688.1	0.05	Other	N-tetradecanoyl tyrosine	uncultured bacterium CSLC2
BGC0000806.1	0.04	Saccharide	phosphonoglycans	Glycomyces sp. NRRL B-16210

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000887.1	0.44	Alkaloid	saxitoxin, gonyautoxin 2, gonyautoxin 3, toxin C2, toxin C3, gonyautoxin 5, decarbamoylsaxitoxin, decarbamoylgonyautoxin 2, decarbamoylgonyautoxin 3	Dolichospermum circinale AWQC131C
BGC0000472.1	0.38	RiPP	anacyclamide A10	Anabaena sp. 90
BGC0000565.1	0.35	RiPP	goadsporin	Streptomyces sp. TP-A0584
BGC0001591.1	0.23	Other	fatty acid enol ester	uncultured bacterium CSLC2
BGC0001688.1	0.23	Other	N-tetradecanoyl tyrosine	uncultured bacterium CSLC2
BGC0000806.1	0.20	Saccharide	phosphonoglycans	Glycomyces sp. NRRL B-16210

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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NZ_CP013019.1 - Region 6 - ranthipeptide

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Location: 2,382,073 - 2,403,693 nt. (total: 21,621 nt) Show pHMM detection rules used

ranthipeptide: (TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085 or SPASM)) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716 or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or YcaO or TIGR03882)))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000599.1	0.17	RiPP	thuricin CD α, thuricin CD β	Bacillus thuringiensis
BGC0001595.1	0.10	Alkaloid	fischerindole	Fischerella sp. SAG 46.79
BGC0001591.1	0.10	Other	fatty acid enol ester	uncultured bacterium CSLC2
BGC0001688.1	0.10	Other	N-tetradecanoyl tyrosine	uncultured bacterium CSLC2
BGC0000613.1	0.10	RiPP	thiomuracin A	Nonomuraea sp. Bp3714-39
BGC0001860.1	0.10	RiPP	thiomuracin	Thermobispora bispora DSM 43833
BGC0001387.1	0.09	Other	nucleocidin	Streptomyces calvus
BGC0001155.1	0.09	RiPP	GE2270	Planobispora rosea
BGC0000604.1	0.08	RiPP	GE2270A	Nonomuraea sp. WU8817
BGC0000825.1	0.07	Alkaloid	staurosporine	Streptomyces sp. TP-A0274

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000599.1	0.48	RiPP	thuricin CD α, thuricin CD β	Bacillus thuringiensis
BGC0001595.1	0.36	Alkaloid	fischerindole	Fischerella sp. SAG 46.79
BGC0001591.1	0.36	Other	fatty acid enol ester	uncultured bacterium CSLC2
BGC0001688.1	0.36	Other	N-tetradecanoyl tyrosine	uncultured bacterium CSLC2
BGC0000613.1	0.35	RiPP	thiomuracin A	Nonomuraea sp. Bp3714-39
BGC0001860.1	0.35	RiPP	thiomuracin	Thermobispora bispora DSM 43833
BGC0001387.1	0.34	Other	nucleocidin	Streptomyces calvus
BGC0001155.1	0.33	RiPP	GE2270	Planobispora rosea
BGC0000604.1	0.30	RiPP	GE2270A	Nonomuraea sp. WU8817
BGC0000825.1	0.29	Alkaloid	staurosporine	Streptomyces sp. TP-A0274

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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NZ_CP013019.1 - Region 7 - cyclic-lactone-autoinducer

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Location: 2,670,330 - 2,688,177 nt. (total: 17,848 nt) Show pHMM detection rules used

cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000616.1	0.16	RiPP	amylocyclicin	Bacillus velezensis FZB42
BGC0000528.1	0.16	RiPP	michiganin A	Clavibacter michiganensis subsp. michiganensis NCPPB 382
BGC0000928.1	0.15	Other	T3 toxin	Cylindrospermopsis raciborskii T3
BGC0000188.1	0.15	Alkaloid	saxitoxin, neosaxitoxin, decarbamoylsaxitoxin, gonyautoxin 3, gonyautoxin 2	Cylindrospermopsis raciborskii T3
BGC0001787.1	0.14	RiPP	suicin 3908	Streptococcus suis
BGC0000774.1	0.14	Saccharide	lipopolysaccharide	Xanthomonas campestris pv. campestris
BGC0000561.1	0.14	RiPP	thermophilin 1277	Streptococcus thermophilus
BGC0000498.1	0.14	RiPP	bovicin HJ50	Streptococcus equinus
BGC0000734.1	0.14	Saccharide	capsular polysaccharide	Pasteurella multocida
BGC0000735.1	0.13	Saccharide	capsular polysaccharide	Pasteurella multocida

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000616.1	0.47	RiPP	amylocyclicin	Bacillus velezensis FZB42
BGC0000528.1	0.46	RiPP	michiganin A	Clavibacter michiganensis subsp. michiganensis NCPPB 382
BGC0000928.1	0.45	Other	T3 toxin	Cylindrospermopsis raciborskii T3
BGC0000188.1	0.45	Alkaloid	saxitoxin, neosaxitoxin, decarbamoylsaxitoxin, gonyautoxin 3, gonyautoxin 2	Cylindrospermopsis raciborskii T3
BGC0001787.1	0.44	RiPP	suicin 3908	Streptococcus suis
BGC0000774.1	0.43	Saccharide	lipopolysaccharide	Xanthomonas campestris pv. campestris
BGC0000561.1	0.43	RiPP	thermophilin 1277	Streptococcus thermophilus
BGC0000498.1	0.43	RiPP	bovicin HJ50	Streptococcus equinus
BGC0000734.1	0.43	Saccharide	capsular polysaccharide	Pasteurella multocida
BGC0000735.1	0.42	Saccharide	capsular polysaccharide	Pasteurella multocida

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NZ_CP013019.1 - Region 8 - cyclic-lactone-autoinducer

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Location: 2,732,238 - 2,751,830 nt. (total: 19,593 nt) Show pHMM detection rules used

cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001387.1	0.15	Other	nucleocidin	Streptomyces calvus
BGC0001607.1	0.14	Other	gilvusmycin	Streptomyces sp. NRRL B-1347
BGC0000928.1	0.12	Other	T3 toxin	Cylindrospermopsis raciborskii T3
BGC0000188.1	0.12	Alkaloid	saxitoxin, neosaxitoxin, decarbamoylsaxitoxin, gonyautoxin 3, gonyautoxin 2	Cylindrospermopsis raciborskii T3
BGC0000043.1	0.12	Polyketide	curacin A	Moorea producens 19L
BGC0000527.1	0.12	RiPP	mersacidin	Bacillus sp. HIL-Y85/54728
BGC0001789.1	0.11	RiPP	suicin 90-1330	Streptococcus suis
BGC0000537.1	0.11	RiPP	nisin U	Streptococcus uberis
BGC0000535.1	0.11	RiPP	nisin A	Lactococcus lactis subsp. lactis
BGC0000536.1	0.11	RiPP	nisin Q	Lactococcus lactis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001387.1	0.45	Other	nucleocidin	Streptomyces calvus
BGC0001607.1	0.44	Other	gilvusmycin	Streptomyces sp. NRRL B-1347
BGC0000928.1	0.40	Other	T3 toxin	Cylindrospermopsis raciborskii T3
BGC0000188.1	0.40	Alkaloid	saxitoxin, neosaxitoxin, decarbamoylsaxitoxin, gonyautoxin 3, gonyautoxin 2	Cylindrospermopsis raciborskii T3
BGC0000043.1	0.40	Polyketide	curacin A	Moorea producens 19L
BGC0000527.1	0.39	RiPP	mersacidin	Bacillus sp. HIL-Y85/54728
BGC0001789.1	0.37	RiPP	suicin 90-1330	Streptococcus suis
BGC0000537.1	0.37	RiPP	nisin U	Streptococcus uberis
BGC0000535.1	0.37	RiPP	nisin A	Lactococcus lactis subsp. lactis
BGC0000536.1	0.37	RiPP	nisin Q	Lactococcus lactis

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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NZ_CP013019.1 - Region 9 - cyclic-lactone-autoinducer

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Location: 2,996,968 - 3,014,830 nt. (total: 17,863 nt) Show pHMM detection rules used

cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000488.1	0.19	RiPP	circularin A	Clostridium beijerinckii
BGC0001407.1	0.16	RiPP	bicereucin	Bacillus cereus SJ1
BGC0000517.1	0.16	RiPP	haloduracin β, haloduracin α	Bacillus halodurans C-125
BGC0000543.1	0.16	RiPP	pep5	Staphylococcus epidermidis
BGC0000571.1	0.16	RiPP	burhizin	Paraburkholderia rhizoxinica HKI 454
BGC0000508.1	0.16	RiPP	epidermin	Staphylococcus epidermidis
BGC0000617.1	0.16	RiPP	coagulin	Bacillus coagulans
BGC0000500.1	0.16	RiPP	carnolysin A1, carnolysin A2	Carnobacterium maltaromaticum
BGC0000538.1	0.16	RiPP	nisin Z	Lactococcus lactis
BGC0000554.1	0.16	RiPP	SRO15-3108	Streptomyces filamentosus NRRL 15998

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000488.1	0.51	RiPP	circularin A	Clostridium beijerinckii
BGC0001407.1	0.47	RiPP	bicereucin	Bacillus cereus SJ1
BGC0000517.1	0.47	RiPP	haloduracin β, haloduracin α	Bacillus halodurans C-125
BGC0000543.1	0.47	RiPP	pep5	Staphylococcus epidermidis
BGC0000571.1	0.47	RiPP	burhizin	Paraburkholderia rhizoxinica HKI 454
BGC0000508.1	0.47	RiPP	epidermin	Staphylococcus epidermidis
BGC0000617.1	0.47	RiPP	coagulin	Bacillus coagulans
BGC0000500.1	0.47	RiPP	carnolysin A1, carnolysin A2	Carnobacterium maltaromaticum
BGC0000538.1	0.47	RiPP	nisin Z	Lactococcus lactis
BGC0000554.1	0.46	RiPP	SRO15-3108	Streptomyces filamentosus NRRL 15998

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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NZ_CP013019.1 - Region 10 - NRPS,NRPS-like,T1PKS

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Location: 3,125,445 - 3,181,971 nt. (total: 56,527 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))
NRPS: cds(Condensation and (AMP-binding or A-OX))

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NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001162.1	0.92	Polyketide	1-heptadecene	Moorea producens JHB
BGC0001163.1	0.92	Polyketide	1-heptadecene	Moorea producens 3L
BGC0001161.1	0.92	Polyketide	1-heptadecene	Moorea bouillonii PNG
BGC0001399.1	0.75	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0001831.1	0.69	Polyketide	alkylpyrone-407, alkylpyrone-393	Myxococcus xanthus DK 1622
BGC0000195.1	0.66	Polyketide	alnumycin A, alnumycin B, alnumycin C, alnumycin P, prealnumycin, thalnumycin A, thalnumycin B, K1115A, 1,6-dihydro-8-propylanthraquinone	Streptomyces sp. CM020
BGC0000348.1	0.65	NRP	ergovaline	Epichloe festucae var. lolii
BGC0001873.1	0.64	NRP	pyrrolizixenamide A	Xenorhabdus szentirmaii DSM 16338
BGC0002000.1	0.62	Polyketide	setomimycin	Streptomyces aurantiacus JA 4570
BGC0000679.1	0.62	Terpene	diazepinomicin	Micromonospora sp. M42

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001162.1	0.64	Polyketide	1-heptadecene	Moorea producens JHB
BGC0001163.1	0.64	Polyketide	1-heptadecene	Moorea producens 3L
BGC0001161.1	0.64	Polyketide	1-heptadecene	Moorea bouillonii PNG
BGC0001399.1	0.58	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0000195.1	0.57	Polyketide	alnumycin A, alnumycin B, alnumycin C, alnumycin P, prealnumycin, thalnumycin A, thalnumycin B, K1115A, 1,6-dihydro-8-propylanthraquinone	Streptomyces sp. CM020
BGC0001831.1	0.56	Polyketide	alkylpyrone-407, alkylpyrone-393	Myxococcus xanthus DK 1622
BGC0001927.1	0.55	Other	A-94964	Streptomyces sp.
BGC0000838.1	0.55	Polyketide	flexirubin	Flavobacterium johnsoniae UW101
BGC0000348.1	0.54	NRP	ergovaline	Epichloe festucae var. lolii
BGC0000679.1	0.54	Terpene	diazepinomicin	Micromonospora sp. M42

Similar known gene clusters

No matches found.

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Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 12, location 3125444 - 3181971:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ohmal)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 13, location 3125444 - 3174768:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ohmal)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 14, location 3136097 - 3181971:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ohmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg1_2862

CAL_domain (162..469): pk

minowa: fatty_acid

Prediction, score:

fatty_acid: 122.2
NH2: 24.3
shikimic_acid: 0.0
Acetyl-CoA: 0.0
AHBA: 0.0

ctg1_2863

CAL_domain (187..487): pk

minowa: fatty_acid

Prediction, score:

fatty_acid: 81.5
NH2: 17.8
shikimic_acid: 0.0
Acetyl-CoA: 0.0
AHBA: 0.0

PKS_AT (1263..1556): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 83.3%; inactive: 75.0%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 113.4
inactive: 82.1
Methoxymalonyl-CoA: 40.0
Methylmalonyl-CoA: 33.9
Propionyl-CoA: 21.4
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

ctg1_2865

Search NORINE for peptide: strict or relaxed

AMP-binding (686..1111): ser

NRPSPredictor2: ser

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: ser
Single AA prediction:: ser

Stachelhaus prediction details:

Stachelhaus sequence:: DiWHISLIDK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 90% (moderate)

NZ_CP013019.1 - Region 11 - cyclic-lactone-autoinducer

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Location: 3,555,093 - 3,575,746 nt. (total: 20,654 nt) Show pHMM detection rules used

cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

Legend:

core biosynthetic genes

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Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001654.1	0.15	Saccharide	lipooligosaccharide	Bacteroides thetaiotaomicron VPI-5482
BGC0002026.1	0.09	NRP	thaxteramide A1, thaxteramide A2, thaxteramide B1, thaxteramide B2	Jahnella sp. MSr9139
BGC0000632.1	0.06	Terpene, Saccharide	brasilicardin A	Nocardia terpenica
BGC0000446.1	0.05	NRP	tilivalline, 9-deoxy tilivalline, dihydroxy tilivalline, dehydro tilivalline, dihydroxy-dehydro tilivalline	Klebsiella oxytoca
BGC0001805.1	0.05	NRP	tilivalline	Klebsiella oxytoca
BGC0000982.1	0.05	NRP, Polyketide	cystothiazole A	Cystobacter fuscus
BGC0000458.1	0.05	NRP	viomycin	Streptomyces vinaceus
BGC0001055.1	0.05	NRP, Polyketide	yersiniabactin	Escherichia coli
BGC0000434.1	0.05	NRP	SW-163C, UK-63598, SW-163E, SW-163F, SW-163G	Streptomyces sp. SNA15896
BGC0000433.1	0.04	NRP	surfactin	Bacillus velezensis FZB42

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001654.1	0.46	Saccharide	lipooligosaccharide	Bacteroides thetaiotaomicron VPI-5482
BGC0002026.1	0.33	NRP	thaxteramide A1, thaxteramide A2, thaxteramide B1, thaxteramide B2	Jahnella sp. MSr9139
BGC0000632.1	0.25	Terpene, Saccharide	brasilicardin A	Nocardia terpenica
BGC0000446.1	0.24	NRP	tilivalline, 9-deoxy tilivalline, dihydroxy tilivalline, dehydro tilivalline, dihydroxy-dehydro tilivalline	Klebsiella oxytoca
BGC0001805.1	0.24	NRP	tilivalline	Klebsiella oxytoca
BGC0000982.1	0.22	NRP, Polyketide	cystothiazole A	Cystobacter fuscus
BGC0000458.1	0.22	NRP	viomycin	Streptomyces vinaceus
BGC0001055.1	0.21	NRP, Polyketide	yersiniabactin	Escherichia coli
BGC0000434.1	0.21	NRP	SW-163C, UK-63598, SW-163E, SW-163F, SW-163G	Streptomyces sp. SNA15896
BGC0000433.1	0.21	NRP	surfactin	Bacillus velezensis FZB42

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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