LOCUS       c00018_NZ_CABK..       21866 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CABKTQ010000021.1 Bacillus rubiinfantis isolate MGYG-HGUT-01475,
            whole genome shotgun sequence.
ACCESSION   c00018_NZ_CABK..
VERSION     c00018_NZ_CABK..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:29:53
            Original ID  :: NZ_CABKTQ010000021.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 282196
            Orig. end    :: 304062
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21866
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[292196:294062](-)"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11866)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     cand_cluster    1..21866
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21866
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(Terpene_synth or Terpene_synth_C or phytoene_synt
                     or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps
                     or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /tool="antismash"
     CDS             283..1260
                     /locus_tag="ctg18_309"
                     /transl_table=11
                     /translation="MRPIIIGIFAAFFFAFTFVLNRAMDLAGGSWIWSASLRYFFMIPF
                     LFLIVMARKNLKELWLEMKQQPYKWFVWSSIGFGLFYAPLCFSAAFAPGWLIAATWQIT
                     IISGSLLAPLFYEIVMTSKGPALRKGKIPFRGMAMSMIILLGIILMQLQQASRLSLLEI
                     SLGIVPVIVASFAYPLGNRKMMDVCGGRLDVFQRVLGMTLASMPFWIVLSLYGFFTVGL
                     PSIDQTVQSSLVAVSSGVIATVLFFQATDLVRGNMQKLAAVEATQSLEVLFALLGEIVL
                     LNSVFPSSLSWAGMVLVMAGMILHSYSSHRQKHTIKPVEKSLSS"
     PFAM_domain     394..1197
                     /aSDomain="EmrE"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13536.8"
                     /description="Putative multidrug resistance efflux
                     transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_309_0001"
                     /evalue="4.60E-115"
                     /label="ctg18_309"
                     /locus_tag="ctg18_309"
                     /protein_end="305"
                     /protein_start="37"
                     /score="383.7"
                     /tool="antismash"
                     /translation="RYFFMIPFLFLIVMARKNLKELWLEMKQQPYKWFVWSSIGFGLFY
                     APLCFSAAFAPGWLIAATWQITIISGSLLAPLFYEIVMTSKGPALRKGKIPFRGMAMSM
                     IILLGIILMQLQQASRLSLLEISLGIVPVIVASFAYPLGNRKMMDVCGGRLDVFQRVLG
                     MTLASMPFWIVLSLYGFFTVGLPSIDQTVQSSLVAVSSGVIATVLFFQATDLVRGNMQK
                     LAAVEATQSLEVLFALLGEIVLLNSVFPSSLSWAGMVLVMAGMILH"
     CDS             2031..2189
                     /locus_tag="ctg18_310"
                     /transl_table=11
                     /translation="MEKRKSQKNNDPALAPGINDLEELQKSASEEEINNGEYTHVITLK
                     LDDADPS"
     CDS             complement(2306..2557)
                     /locus_tag="ctg18_311"
                     /transl_table=11
                     /translation="MDKTLLYLRETLSNYTDGHTEGHQIYHKLVKGNYKSEENFVRSLN
                     PKEIDFLNRVMEAEISYAQDVQDDKRLYELNEVYELLF"
     PFAM_domain     complement(2309..2557)
                     /aSDomain="CsgA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF17334.4"
                     /description="Minor curli fiber component A"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_311_0002"
                     /evalue="5.90E-36"
                     /label="ctg18_311"
                     /locus_tag="ctg18_311"
                     /protein_end="83"
                     /protein_start="0"
                     /score="123.2"
                     /tool="antismash"
                     /translation="MDKTLLYLRETLSNYTDGHTEGHQIYHKLVKGNYKSEENFVRSLN
                     PKEIDFLNRVMEAEISYAQDVQDDKRLYELNEVYELLF"
     CDS             complement(2699..3412)
                     /NRPS_PKS="Domain: oMT (34-145). E-value: 4.9e-16. Score:
                     49.6. Matches aSDomain: nrpspksdomains_ctg18_312_oMT.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 110.7; E-value:
                     1.4e-33)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_312"
                     /transl_table=11
                     /translation="MGGLTYIDFLAKFGVGGAHPGGINLTKNVLSQEKISSNSSILDAG
                     CGTGQTAAFMYERYQANIVCLELNPIMVEKAKNRFQLLKYPIQLVQGSVEDIPFPDDSF
                     EFILCESVLAFVNKPQALHEFYRVLKTGGRLLANEMTINSSLPEDAKREIMEFYNIDSL
                     LLESDWRTLLQASGFKEIDIRQLQSDLMNGNTAQEFNFSQNFEPELFSILNQHGNMLVK
                     YHDILSHRIFTCTKI"
     aSDomain        complement(2978..3310)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg18_312_oMT.1"
                     /domain_subtype="oMT"
                     /evalue="4.90E-16"
                     /label="ctg18_312_oMT.1"
                     /locus_tag="ctg18_312"
                     /protein_end="145"
                     /protein_start="34"
                     /score="49.6"
                     /tool="antismash"
                     /translation="ISSNSSILDAGCGTGQTAAFMYERYQANIVCLELNPIMVEKAKNR
                     FQLLKYPIQLVQGSVEDIPFPDDSFEFILCESVLAFVNKPQALHEFYRVLKTGGRLLAN
                     EMTINSS"
     PFAM_domain     complement(3005..3289)
                     /aSDomain="Methyltransf_11"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08241.14"
                     /description="Methyltransferase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_312_0003"
                     /evalue="2.20E-22"
                     /label="ctg18_312"
                     /locus_tag="ctg18_312"
                     /protein_end="136"
                     /protein_start="41"
                     /score="79.6"
                     /tool="antismash"
                     /translation="LDAGCGTGQTAAFMYERYQANIVCLELNPIMVEKAKNRFQLLKYP
                     IQLVQGSVEDIPFPDDSFEFILCESVLAFVNKPQALHEFYRVLKTGGRLL"
     CDS             3634..3927
                     /locus_tag="ctg18_313"
                     /transl_table=11
                     /translation="MRKSVIKMFRPKRRNNGAIWASLASIGIGAAVYGMTRGKQNNQAL
                     PLTDTMRNLASPLKETVKNIVPKMNIGKMNTAQLAEFSEDLMNGALHNQKSK"
     CDS             complement(3968..4852)
                     /locus_tag="ctg18_314"
                     /transl_table=11
                     /translation="MLKLSWILTIFLAAHPVNEANDIAITKDGVSLTTINRYDFFHPYS
                     DLPIMNNKKFNRFLYQLNQQVSTEPKNAYINNKGQIIPEKPGSEINKEAFAKELYSIFY
                     QNNKPTLEIPMNTAYPKVDSELLSNIRTVRIGRYVTSFNPGNKNRSFNIKLAAEAINNY
                     VVFPNEIFSFNKVVGKRTKQKGYLKAPVIVKGEYSEDIGGGICQVSSTLFNAVDNAGLA
                     IIQRFSHSKDVSYIPPGRDATVSWYGPDFVFKNKYQQPILIRARTMGSLLIINLYSSDG
                     IQYKPKNIPPPPK"
     PFAM_domain     complement(4022..4411)
                     /aSDomain="VanW"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04294.15"
                     /description="VanW like protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_314_0005"
                     /evalue="1.70E-48"
                     /label="ctg18_314"
                     /locus_tag="ctg18_314"
                     /protein_end="277"
                     /protein_start="147"
                     /score="163.6"
                     /tool="antismash"
                     /translation="NRSFNIKLAAEAINNYVVFPNEIFSFNKVVGKRTKQKGYLKAPVI
                     VKGEYSEDIGGGICQVSSTLFNAVDNAGLAIIQRFSHSKDVSYIPPGRDATVSWYGPDF
                     VFKNKYQQPILIRARTMGSLLIINLY"
     PFAM_domain     complement(4556..4705)
                     /aSDomain="PG_binding_4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12229.10"
                     /description="Putative peptidoglycan binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_314_0004"
                     /evalue="4.30E-05"
                     /label="ctg18_314"
                     /locus_tag="ctg18_314"
                     /protein_end="99"
                     /protein_start="49"
                     /score="23.8"
                     /tool="antismash"
                     /translation="MNNKKFNRFLYQLNQQVSTEPKNAYINNKGQIIPEKPGSEINKEA
                     FAKEL"
     CDS             5069..5473
                     /locus_tag="ctg18_315"
                     /transl_table=11
                     /translation="MEHEIQVIARFSETDALGHINNTSYFIYLEEARIRFLEMLGFDLN
                     GQNFSFILASAKCDYISQGFFNQQLRITTYVTKIGTKSFQLEHDIINKDTNQLIAHGQV
                     VMVYFDFEKQQSKPLPELMKQGLNTYLVHL"
     PFAM_domain     5096..5440
                     /aSDomain="4HBT_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13279.8"
                     /description="Thioesterase-like superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_315_0006"
                     /evalue="2.40E-19"
                     /label="ctg18_315"
                     /locus_tag="ctg18_315"
                     /protein_end="124"
                     /protein_start="9"
                     /score="70.1"
                     /tool="antismash"
                     /translation="RFSETDALGHINNTSYFIYLEEARIRFLEMLGFDLNGQNFSFILA
                     SAKCDYISQGFFNQQLRITTYVTKIGTKSFQLEHDIINKDTNQLIAHGQVVMVYFDFEK
                     QQSKPLPELMK"
     CDS             5691..6389
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 217; E-value: 4e-66)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg18_316"
                     /transl_table=11
                     /translation="LKILVIEDNKSVCSMIEMFFAKEGIEGVFVNDGLEGYQRFKSGTW
                     DALIVDWMLPGLDGVTICRRIREEQYSVPIIMLTAKDSESDQVLGLEMGADDYVTKPFS
                     PLTLMARIKAVTRRYQNQVPKELDGLLQTEHFKINKTTREVYVDGVPITNLTPKEFDLL
                     FYLVEHPRQVFSREQLLESVWGYQFYGDERTVDVHIKRLRKKLETVSQFFHTVWGVGYK
                     FDDTTKADEI"
     PFAM_domain     5697..6029
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_316_0007"
                     /evalue="1.30E-25"
                     /label="ctg18_316"
                     /locus_tag="ctg18_316"
                     /protein_end="113"
                     /protein_start="2"
                     /score="89.8"
                     /tool="antismash"
                     /translation="ILVIEDNKSVCSMIEMFFAKEGIEGVFVNDGLEGYQRFKSGTWDA
                     LIVDWMLPGLDGVTICRRIREEQYSVPIIMLTAKDSESDQVLGLEMGADDYVTKPFSPL
                     TLMARIK"
     PFAM_domain     6150..6359
                     /aSDomain="Trans_reg_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00486.30"
                     /description="Transcriptional regulatory protein, C
                     terminal"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_316_0008"
                     /evalue="7.20E-29"
                     /label="ctg18_316"
                     /locus_tag="ctg18_316"
                     /protein_end="223"
                     /protein_start="153"
                     /score="99.8"
                     /tool="antismash"
                     /translation="NLTPKEFDLLFYLVEHPRQVFSREQLLESVWGYQFYGDERTVDVH
                     IKRLRKKLETVSQFFHTVWGVGYKF"
     CDS             6361..7788
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 246.1; E-value: 1.7e-74)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg18_317"
                     /transl_table=11
                     /translation="MTQRKPMKFKYFYQQFFSHISIIIVAFLLLSLLFAHYLENLVYEN
                     KTDELISYGKAILAEIKEDPLRTEDVVKQYSDVLAARKMSFSMFDQDGNLYFVNNQGPA
                     IKNLPRSDWQKLTKGQTIVVQSDYKRFDQDGVTFVVLPYLYQDKFFGGILLTSPISGSI
                     KMIHEINKILLSTILIAFGVSFLQSWFLSQIHVRRIQRLRDATSSVSAGNYNVHVHSSN
                     YDEIGELASDFNNMVDTINASMLEIESLENRRRQFMADVSHEMRTPLTTISGVIEGLKN
                     NMIPEEDKEKGINLVSQEAKRLIRLVNENLDYEKIRSNQIRLFKEDIQLTEVLEIIQEQ
                     LSLQAEEKNNQLIVEASPEVYVFADYDRLVQILINITKNSIQFTSDGTIWLRGQAEGNH
                     VIIEVEDTGIGIDASEVENIWRRFYKADLSRTSNPYGEFGLGLSIVKQLVQLHNGEINV
                     TSEKGKGTKFVIRFPKK"
     PFAM_domain     6931..7083
                     /aSDomain="HAMP"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00672.27"
                     /description="HAMP domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_317_0009"
                     /evalue="1.80E-09"
                     /label="ctg18_317"
                     /locus_tag="ctg18_317"
                     /protein_end="241"
                     /protein_start="190"
                     /score="37.9"
                     /tool="antismash"
                     /translation="LSQIHVRRIQRLRDATSSVSAGNYNVHVHSSNYDEIGELASDFNN
                     MVDTIN"
     PFAM_domain     7120..7314
                     /aSDomain="HisKA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00512.27"
                     /description="His Kinase A (phospho-acceptor) domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_317_0010"
                     /evalue="7.10E-14"
                     /label="ctg18_317"
                     /locus_tag="ctg18_317"
                     /protein_end="318"
                     /protein_start="253"
                     /score="51.7"
                     /tool="antismash"
                     /translation="RRQFMADVSHEMRTPLTTISGVIEGLKNNMIPEEDKEKGINLVSQ
                     EAKRLIRLVNENLDYEKIRS"
     PFAM_domain     7453..7782
                     /aSDomain="HATPase_c"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02518.28"
                     /description="Histidine kinase-, DNA gyrase B-, and
                     HSP90-like ATPase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_317_0011"
                     /evalue="3.50E-26"
                     /label="ctg18_317"
                     /locus_tag="ctg18_317"
                     /protein_end="474"
                     /protein_start="364"
                     /score="92.0"
                     /tool="antismash"
                     /translation="DYDRLVQILINITKNSIQFTSDGTIWLRGQAEGNHVIIEVEDTGI
                     GIDASEVENIWRRFYKADLSRTSNPYGEFGLGLSIVKQLVQLHNGEINVTSEKGKGTKF
                     VIRFPK"
     CDS             7951..9345
                     /locus_tag="ctg18_318"
                     /transl_table=11
                     /translation="MDNKEPLDQETSIDVSIPAKTTVDNKDITNETIQSENHEPQICSQ
                     EEESKQESPNSDLNTSQTVTAGNNLKNSYGTKKKIKGAASTIAAGVIGSVLTLAILPHT
                     NYVKNFQGSEAPAVAQAEQVSGQVKPVTTQKSSSNSIADTVEKLSKTIVGIENYQQQQS
                     IDFFGNKQSSQNVEAGSGSGVIFQKTNGSAYVVTNNHVVEGASRLEVSLYNGSKTSATV
                     IGTDALTDLAVLKIDDKNVTDTASFGDSSSLRPGDQVYAIGNPLGSELSRTVTQGIVSA
                     TNRSISVSTSAGDWETTVIQTDAAINPGNSGGALINNQGQVVGINSMKISENGVEGLGF
                     AIPSNDVIPIVNQLIKNGKIDRPYLGVGLADLDEVSRVYLAELPDKVTQGALVMNIDAN
                     SAAAKAGFQPKDVIVSMNGEKITNSSDLRKYLYTKAKIGDDIRFKVYRDGKRITLTAKL
                     TNNRTN"
     PFAM_domain     8491..8925
                     /aSDomain="Trypsin_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13365.8"
                     /description="Trypsin-like peptidase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_318_0012"
                     /evalue="8.20E-30"
                     /label="ctg18_318"
                     /locus_tag="ctg18_318"
                     /protein_end="325"
                     /protein_start="180"
                     /score="104.9"
                     /tool="antismash"
                     /translation="GSGVIFQKTNGSAYVVTNNHVVEGASRLEVSLYNGSKTSATVIGT
                     DALTDLAVLKIDDKNVTDTASFGDSSSLRPGDQVYAIGNPLGSELSRTVTQGIVSATNR
                     SISVSTSAGDWETTVIQTDAAINPGNSGGALINNQGQVVGI"
     PFAM_domain     9037..9324
                     /aSDomain="PDZ_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13180.8"
                     /description="PDZ domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_318_0013"
                     /evalue="3.70E-20"
                     /label="ctg18_318"
                     /locus_tag="ctg18_318"
                     /protein_end="458"
                     /protein_start="362"
                     /score="72.2"
                     /tool="antismash"
                     /translation="PYLGVGLADLDEVSRVYLAELPDKVTQGALVMNIDANSAAAKAGF
                     QPKDVIVSMNGEKITNSSDLRKYLYTKAKIGDDIRFKVYRDGKRITLTAKL"
     CDS             9448..9951
                     /locus_tag="ctg18_319"
                     /transl_table=11
                     /translation="LKEVDDRIKENLNILFVGFNPSIRSSETGHHFANPNNRFWRILVE
                     SGLTSRKFSPEEDDLLLDLGYGITNIVARPTKAADEITKQEYMVGRKILIQKITRFQPK
                     IICYVGKGVYLQFSGKKTAPWGVQEEAVVPDTIDFVAPSSSGLVRMKLEEMVDIYKELR
                     ELIA"
     PFAM_domain     9472..9933
                     /aSDomain="UDG"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03167.21"
                     /description="Uracil DNA glycosylase superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_319_0014"
                     /evalue="4.70E-22"
                     /label="ctg18_319"
                     /locus_tag="ctg18_319"
                     /protein_end="162"
                     /protein_start="8"
                     /score="78.7"
                     /tool="antismash"
                     /translation="KENLNILFVGFNPSIRSSETGHHFANPNNRFWRILVESGLTSRKF
                     SPEEDDLLLDLGYGITNIVARPTKAADEITKQEYMVGRKILIQKITRFQPKIICYVGKG
                     VYLQFSGKKTAPWGVQEEAVVPDTIDFVAPSSSGLVRMKLEEMVDIYKEL"
     CDS             complement(10001..11866)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: terpene_cyclase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_320"
                     /sec_met_domain="terpene_cyclase (E-value: 2.6e-18,
                     bitscore: 61.6, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VVETKEGINWLIETLRNDQSHDGSWNYPFDTGISTDAYMIILLRS
                     LEIDEEELIKGLCKRILSKQTRYGTWKLFYDEGKGNVTATLEAYYALLYSGYYSKTDKR
                     LELAKKFIKTNGGIEAVSIFTKIMLAITGQYKWPNHSPLPIEMILLPPIFPINFFSFSI
                     FGRANLTPIMILAAKNYSLKTVKSPVLTDLVTHRNIEDPWIRSEEWRSLLSLIKEGVKN
                     LVGLPEELRSLALERGKKYMLERIEVNGTLCSYYSSTFLMIFALLALGYKKTDHVITQA
                     IAGLKSMKCEINGLPHMQYTTANVWNTALITHALQFAGVSSKDPMVAKSHQYLLSRQQQ
                     RFGDWVVHNPTSLPGGWGFSDINTFVPDVDDTTAALRSISRIVPPENVAWERGISWTLS
                     MQNADGGWPAFEKNTDSKLLEWLPLDKAKFLLLDPSCADLTGRTLEFFGHYTNLSENHP
                     VIKKGIRWIKKKQEKDGSWYGRWGISYLYGTWAAITGLRAVGVTNNDSSIDTAINWLRN
                     IQNKDGGWGESCHSDVQNRYVPLGSSTVVHTAWVVDALLSASDRPTNEITRGMNYLLSS
                     LKHEDWTMDYPNGQGMGGAFYIHYHSYRYIFPLLTLAHYQQKFGN"
     aSDomain        complement(10013..11854)
                     /aSDomain="TIGR01507"
                     /aSTool="tigrfam"
                     /description="hopene_cyclase: squalene-hopene cyclase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg18_320_0001"
                     /evalue="1.10E-130"
                     /identifier="TIGR01507"
                     /label="ctg18_320"
                     /locus_tag="ctg18_320"
                     /protein_end="618"
                     /protein_start="4"
                     /score="434.9"
                     /tool="antismash"
                     /translation="KEGINWLIETLRNDQSHDGSWNYPFDTGISTDAYMIILLRSLEID
                     EEELIKGLCKRILSKQTRYGTWKLFYDEGKGNVTATLEAYYALLYSGYYSKTDKRLELA
                     KKFIKTNGGIEAVSIFTKIMLAITGQYKWPNHSPLPIEMILLPPIFPINFFSFSIFGRA
                     NLTPIMILAAKNYSLKTVKSPVLTDLVTHRNIEDPWIRSEEWRSLLSLIKEGVKNLVGL
                     PEELRSLALERGKKYMLERIEVNGTLCSYYSSTFLMIFALLALGYKKTDHVITQAIAGL
                     KSMKCEINGLPHMQYTTANVWNTALITHALQFAGVSSKDPMVAKSHQYLLSRQQQRFGD
                     WVVHNPTSLPGGWGFSDINTFVPDVDDTTAALRSISRIVPPENVAWERGISWTLSMQNA
                     DGGWPAFEKNTDSKLLEWLPLDKAKFLLLDPSCADLTGRTLEFFGHYTNLSENHPVIKK
                     GIRWIKKKQEKDGSWYGRWGISYLYGTWAAITGLRAVGVTNNDSSIDTAINWLRNIQNK
                     DGGWGESCHSDVQNRYVPLGSSTVVHTAWVVDALLSASDRPTNEITRGMNYLLSSLKHE
                     DWTMDYPNGQGMGGAFYIHYHSYRYIFPLLTLAHYQQK"
     PFAM_domain     complement(10016..10957)
                     /aSDomain="SQHop_cyclase_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13243.8"
                     /description="Squalene-hopene cyclase C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_320_0016"
                     /evalue="2.80E-92"
                     /label="ctg18_320"
                     /locus_tag="ctg18_320"
                     /protein_end="617"
                     /protein_start="303"
                     /score="309.3"
                     /tool="antismash"
                     /translation="NVWNTALITHALQFAGVSSKDPMVAKSHQYLLSRQQQRFGDWVVH
                     NPTSLPGGWGFSDINTFVPDVDDTTAALRSISRIVPPENVAWERGISWTLSMQNADGGW
                     PAFEKNTDSKLLEWLPLDKAKFLLLDPSCADLTGRTLEFFGHYTNLSENHPVIKKGIRW
                     IKKKQEKDGSWYGRWGISYLYGTWAAITGLRAVGVTNNDSSIDTAINWLRNIQNKDGGW
                     GESCHSDVQNRYVPLGSSTVVHTAWVVDALLSASDRPTNEITRGMNYLLSSLKHEDWTM
                     DYPNGQGMGGAFYIHYHSYRYIFPLLTLAHYQQ"
     aSDomain        complement(10016..11830)
                     /aSDomain="TIGR01787"
                     /aSTool="tigrfam"
                     /description="squalene_cyclas: squalene/oxidosqualene
                     cyclases"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg18_320_0002"
                     /evalue="3.80E-121"
                     /identifier="TIGR01787"
                     /label="ctg18_320"
                     /locus_tag="ctg18_320"
                     /protein_end="617"
                     /protein_start="12"
                     /score="403.6"
                     /tool="antismash"
                     /translation="ETLRNDQSHDGSWNYPFDTGISTDAYMIILLRSLEIDEEELIKGL
                     CKRILSKQTRYGTWKLFYDEGKGNVTATLEAYYALLYSGYYSKTDKRLELAKKFIKTNG
                     GIEAVSIFTKIMLAITGQYKWPNHSPLPIEMILLPPIFPINFFSFSIFGRANLTPIMIL
                     AAKNYSLKTVKSPVLTDLVTHRNIEDPWIRSEEWRSLLSLIKEGVKNLVGLPEELRSLA
                     LERGKKYMLERIEVNGTLCSYYSSTFLMIFALLALGYKKTDHVITQAIAGLKSMKCEIN
                     GLPHMQYTTANVWNTALITHALQFAGVSSKDPMVAKSHQYLLSRQQQRFGDWVVHNPTS
                     LPGGWGFSDINTFVPDVDDTTAALRSISRIVPPENVAWERGISWTLSMQNADGGWPAFE
                     KNTDSKLLEWLPLDKAKFLLLDPSCADLTGRTLEFFGHYTNLSENHPVIKKGIRWIKKK
                     QEKDGSWYGRWGISYLYGTWAAITGLRAVGVTNNDSSIDTAINWLRNIQNKDGGWGESC
                     HSDVQNRYVPLGSSTVVHTAWVVDALLSASDRPTNEITRGMNYLLSSLKHEDWTMDYPN
                     GQGMGGAFYIHYHSYRYIFPLLTLAHYQQ"
     PFAM_domain     complement(10994..11830)
                     /aSDomain="SQHop_cyclase_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13249.8"
                     /description="Squalene-hopene cyclase N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_320_0015"
                     /evalue="3.00E-65"
                     /label="ctg18_320"
                     /locus_tag="ctg18_320"
                     /protein_end="291"
                     /protein_start="12"
                     /score="220.3"
                     /tool="antismash"
                     /translation="ETLRNDQSHDGSWNYPFDTGISTDAYMIILLRSLEIDEEELIKGL
                     CKRILSKQTRYGTWKLFYDEGKGNVTATLEAYYALLYSGYYSKTDKRLELAKKFIKTNG
                     GIEAVSIFTKIMLAITGQYKWPNHSPLPIEMILLPPIFPINFFSFSIFGRANLTPIMIL
                     AAKNYSLKTVKSPVLTDLVTHRNIEDPWIRSEEWRSLLSLIKEGVKNLVGLPEELRSLA
                     LERGKKYMLERIEVNGTLCSYYSSTFLMIFALLALGYKKTDHVITQAIAGLKSMKCE"
     CDS             11978..13078
                     /locus_tag="ctg18_321"
                     /transl_table=11
                     /translation="MSPLEHIRAELRQKSKGPASTPHDLTVQERRLLEKIRRKTEESNS
                     NNITRTKAYLDFYLRYPDIHWAFLGHMVSRNGGWNMTDLQGEFLPRLLSEKERKSFYHF
                     LERGNWLIFQDAFPQFLIYEESLQQQKPLFHLFPFLNVSTFMETVWNHYWKQPDHYLLC
                     MALIINEQHYLEQRVIRQPLYQKEVLHQFKFFLQDLLSFNHILFPYENGKLAGQTMHQF
                     ESLHERILLGKRLYSVLFANKDFLRQVIDWAKRHPHTGSRKDYWPHLFNDVKEGGPGIT
                     YPLRLKSCRLRKGAKRLYSPRLEYAWKNVVQQEAEKGDWFTNEDVANYLVDDTKNIDRE
                     IKHEYCKTLERLEIAAVAKKTINFLG"
     PFAM_domain     12077..13045
                     /aSDomain="DUF2515"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10720.11"
                     /description="Protein of unknown function (DUF2515)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_321_0017"
                     /evalue="5.70E-127"
                     /label="ctg18_321"
                     /locus_tag="ctg18_321"
                     /protein_end="356"
                     /protein_start="33"
                     /score="423.3"
                     /tool="antismash"
                     /translation="EKIRRKTEESNSNNITRTKAYLDFYLRYPDIHWAFLGHMVSRNGG
                     WNMTDLQGEFLPRLLSEKERKSFYHFLERGNWLIFQDAFPQFLIYEESLQQQKPLFHLF
                     PFLNVSTFMETVWNHYWKQPDHYLLCMALIINEQHYLEQRVIRQPLYQKEVLHQFKFFL
                     QDLLSFNHILFPYENGKLAGQTMHQFESLHERILLGKRLYSVLFANKDFLRQVIDWAKR
                     HPHTGSRKDYWPHLFNDVKEGGPGITYPLRLKSCRLRKGAKRLYSPRLEYAWKNVVQQE
                     AEKGDWFTNEDVANYLVDDTKNIDREIKHEYCKTLERLEIAA"
     CDS             13674..14114
                     /locus_tag="ctg18_322"
                     /transl_table=11
                     /translation="MAKKGYIVMENGEKIEFDLFPNEAPGTVANFEKLANEGFYNGVIF
                     HRVIPGFVSQGGDPTGTGMGGPGYTIKCETEGNPHKHVPGALSMAHAGRDTGGSQFFIV
                     HESQPHLDGVHTVFGQVTSGLDTVKAMRNGDKMVEVKVFDEE"
     PFAM_domain     13698..14081
                     /aSDomain="Pro_isomerase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00160.23"
                     /description="Cyclophilin type peptidyl-prolyl cis-trans
                     isomerase/CLD"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_322_0018"
                     /evalue="2.20E-41"
                     /label="ctg18_322"
                     /locus_tag="ctg18_322"
                     /protein_end="136"
                     /protein_start="8"
                     /score="141.8"
                     /tool="antismash"
                     /translation="MENGEKIEFDLFPNEAPGTVANFEKLANEGFYNGVIFHRVIPGFV
                     SQGGDPTGTGMGGPGYTIKCETEGNPHKHVPGALSMAHAGRDTGGSQFFIVHESQPHLD
                     GVHTVFGQVTSGLDTVKAMRNGDK"
     aSDomain        14236..14982
                     /aSDomain="TIGR00633"
                     /aSTool="tigrfam"
                     /description="xth: exodeoxyribonuclease III (xth)"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg18_323_0003"
                     /evalue="2.00E-100"
                     /identifier="TIGR00633"
                     /label="ctg18_323"
                     /locus_tag="ctg18_323"
                     /protein_end="249"
                     /protein_start="0"
                     /score="333.5"
                     /tool="antismash"
                     /translation="MKLISWNVNGLRACVKKGFLDFFHEIDADIFCIQETKLQEGQIQL
                     ELDGYYQYWNYAVKKGYSGTAVFTKVEPISVRYGVGVEESEDEGRILTLEFAEFFLVNV
                     YTPNSQRDLARLGYRLQWEDRIRKYLQELDEQKPVILCGDLNVAHKEIDLRNAKTNIGN
                     SGFTDEEREKMTMLLQSGFIDSFRYFYPEKEGAYTWWSYMNKVRERNIGWRIDYFIVSQ
                     SLTNRLKNAEIYADIMGSDHCPVMLEI"
     aSDomain        14236..14982
                     /aSDomain="TIGR00195"
                     /aSTool="tigrfam"
                     /description="exoDNase_III: exodeoxyribonuclease III"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg18_323_0004"
                     /evalue="1.50E-99"
                     /identifier="TIGR00195"
                     /label="ctg18_323"
                     /locus_tag="ctg18_323"
                     /protein_end="249"
                     /protein_start="0"
                     /score="330.7"
                     /tool="antismash"
                     /translation="MKLISWNVNGLRACVKKGFLDFFHEIDADIFCIQETKLQEGQIQL
                     ELDGYYQYWNYAVKKGYSGTAVFTKVEPISVRYGVGVEESEDEGRILTLEFAEFFLVNV
                     YTPNSQRDLARLGYRLQWEDRIRKYLQELDEQKPVILCGDLNVAHKEIDLRNAKTNIGN
                     SGFTDEEREKMTMLLQSGFIDSFRYFYPEKEGAYTWWSYMNKVRERNIGWRIDYFIVSQ
                     SLTNRLKNAEIYADIMGSDHCPVMLEI"
     CDS             14236..14988
                     /locus_tag="ctg18_323"
                     /transl_table=11
                     /translation="MKLISWNVNGLRACVKKGFLDFFHEIDADIFCIQETKLQEGQIQL
                     ELDGYYQYWNYAVKKGYSGTAVFTKVEPISVRYGVGVEESEDEGRILTLEFAEFFLVNV
                     YTPNSQRDLARLGYRLQWEDRIRKYLQELDEQKPVILCGDLNVAHKEIDLRNAKTNIGN
                     SGFTDEEREKMTMLLQSGFIDSFRYFYPEKEGAYTWWSYMNKVRERNIGWRIDYFIVSQ
                     SLTNRLKNAEIYADIMGSDHCPVMLEIC"
     PFAM_domain     14248..14961
                     /aSDomain="Exo_endo_phos"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03372.25"
                     /description="Endonuclease/Exonuclease/phosphatase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_323_0019"
                     /evalue="2.60E-23"
                     /label="ctg18_323"
                     /locus_tag="ctg18_323"
                     /protein_end="242"
                     /protein_start="4"
                     /score="82.9"
                     /tool="antismash"
                     /translation="SWNVNGLRACVKKGFLDFFHEIDADIFCIQETKLQEGQIQLELDG
                     YYQYWNYAVKKGYSGTAVFTKVEPISVRYGVGVEESEDEGRILTLEFAEFFLVNVYTPN
                     SQRDLARLGYRLQWEDRIRKYLQELDEQKPVILCGDLNVAHKEIDLRNAKTNIGNSGFT
                     DEEREKMTMLLQSGFIDSFRYFYPEKEGAYTWWSYMNKVRERNIGWRIDYFIVSQSLTN
                     RLKNAEIYADIMGSDH"
     CDS             complement(15047..15178)
                     /locus_tag="ctg18_324"
                     /transl_table=11
                     /translation="VPSKRISEANENFDQDVQEQNKPIIETNRLPEFDELGTALNQL"
     CDS             complement(15281..16102)
                     /locus_tag="ctg18_325"
                     /transl_table=11
                     /translation="MKKTALQLIAITFFTISMAYSMNTFLIPHKVLTGGIAGVAMIIHH
                     FLAINTGWIILILNIPLLILGYFYLGRKFMFLTVYSVVLLSVSMKIIPVQEFSNDFLLS
                     SVFGGVINGISIGTIIRLGGSGGGTDIISLILSKKKDLSVGYLNTCVNFIIVLISSLVF
                     GADSTLYTLFAIFASGKAVDTVYTNQTKLAVSIITERWEQLSKELIQLHSRGVTMSDAE
                     GVYSHQHKKVLTTVITKYELTETKEAIKKVDPTAFVYITKAIAVMGRFRRS"
     PFAM_domain     complement(15299..15463)
                     /aSDomain="DUF2179"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10035.11"
                     /description="Uncharacterized protein conserved in bacteria
                     (DUF2179)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_325_0021"
                     /evalue="8.50E-18"
                     /label="ctg18_325"
                     /locus_tag="ctg18_325"
                     /protein_end="268"
                     /protein_start="213"
                     /score="64.0"
                     /tool="antismash"
                     /translation="RGVTMSDAEGVYSHQHKKVLTTVITKYELTETKEAIKKVDPTAFV
                     YITKAIAVMG"
     PFAM_domain     complement(15479..16081)
                     /aSDomain="YitT_membrane"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02588.17"
                     /description="Uncharacterised 5xTM membrane BCR, YitT
                     family COG1284"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_325_0020"
                     /evalue="3.20E-58"
                     /label="ctg18_325"
                     /locus_tag="ctg18_325"
                     /protein_end="208"
                     /protein_start="7"
                     /score="196.6"
                     /tool="antismash"
                     /translation="LIAITFFTISMAYSMNTFLIPHKVLTGGIAGVAMIIHHFLAINTG
                     WIILILNIPLLILGYFYLGRKFMFLTVYSVVLLSVSMKIIPVQEFSNDFLLSSVFGGVI
                     NGISIGTIIRLGGSGGGTDIISLILSKKKDLSVGYLNTCVNFIIVLISSLVFGADSTLY
                     TLFAIFASGKAVDTVYTNQTKLAVSIITERWEQLSKEL"
     CDS             17183..17782
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_326"
                     /sec_met_domain="RmlD_sub_bind (E-value: 1.7e-09, bitscore:
                     32.5, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVLIVGANGMLGSQIVEELKDEFELIRASRQNSDIKVDITSPQS
                     IKKMFETVGKIDALISAAGSTHFGSIESMTPELNAVSLNNKLAGQINLVLLGLDYINDN
                     GSITLTSGVLMDDPVKDGASAAMANGGIKAFVKAAALDMPRGIRLNNVSPTILEESADQ
                     YGELFKGFLPVPGKRVALAYRKSLQGGQTGQTYEIY"
     PFAM_domain     17228..17671
                     /aSDomain="adh_short_C2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13561.8"
                     /description="Enoyl-(Acyl carrier protein) reductase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_326_0022"
                     /evalue="5.40E-14"
                     /label="ctg18_326"
                     /locus_tag="ctg18_326"
                     /protein_end="163"
                     /protein_start="15"
                     /score="52.4"
                     /tool="antismash"
                     /translation="IVEELKDEFELIRASRQNSDIKVDITSPQSIKKMFETVGKIDALI
                     SAAGSTHFGSIESMTPELNAVSLNNKLAGQINLVLLGLDYINDNGSITLTSGVLMDDPV
                     KDGASAAMANGGIKAFVKAAALDMPRGIRLNNVSPTILEESADQ"
     CDS             18007..19182
                     /NRPS_PKS="Domain: Aminotran_1_2 (31-382). E-value:
                     1.7e-61. Score: 200.2. Matches aSDomain:
                     nrpspksdomains_ctg18_327_Aminotran_1_2.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:aminotransferase (Score: 258.4; E-value:
                     1.9e-78)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_327"
                     /transl_table=11
                     /translation="VNFTSNRVGQIPPYLFAEINKKKAEMLKAGIDIIDLGIGDPDLPT
                     PKHIVDKLAEESQDPKNLKYPSFVGCPEFKQAVANFYQREYGVILDPDTEVLALIGSKE
                     GIAHIVPTLVDPGDYVLIPDPSYPVYRMATLLANGQYHNMPLTKENSFKPDFEAIPSEI
                     LGHSKLMFLNYPGNPTSATVDVSFFEKAVAFGKKHNIPIAHDSAYNMVTFDFYKAPSIL
                     EVEGAKEIAVEFGSLSKTYSMTGFRIGYVVGNKEIIKALSVLKSNTDTGQFTPIQKAAA
                     YALNGNQSCVTEYNGIYKERMKAMLDGLKSIGIKVDPPKGSFFIWAPVPNGYTSSEFVT
                     SVLEQTGVIITPGTAFGPSGEGYFRVSLSVPTERLYEAVNRIKEKLKIVMS"
     aSDomain        18100..19152
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg18_327_Aminotran_1_2.1"
                     /evalue="1.70E-61"
                     /label="ctg18_327_Aminotran_1_2.1"
                     /locus_tag="ctg18_327"
                     /protein_end="382"
                     /protein_start="31"
                     /score="200.2"
                     /tool="antismash"
                     /translation="DIIDLGIGDPDLPTPKHIVDKLAEESQDPKNLKYPSFVGCPEFKQ
                     AVANFYQREYGVILDPDTEVLALIGSKEGIAHIVPTLVDPGDYVLIPDPSYPVYRMATL
                     LANGQYHNMPLTKENSFKPDFEAIPSEILGHSKLMFLNYPGNPTSATVDVSFFEKAVAF
                     GKKHNIPIAHDSAYNMVTFDFYKAPSILEVEGAKEIAVEFGSLSKTYSMTGFRIGYVVG
                     NKEIIKALSVLKSNTDTGQFTPIQKAAAYALNGNQSCVTEYNGIYKERMKAMLDGLKSI
                     GIKVDPPKGSFFIWAPVPNGYTSSEFVTSVLEQTGVIITPGTAFGPSGEGYFRVSLSVP
                     TERLYEAVNRI"
     PFAM_domain     18100..19152
                     /aSDomain="Aminotran_1_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00155.23"
                     /description="Aminotransferase class I and II"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_327_0023"
                     /evalue="6.00E-59"
                     /label="ctg18_327"
                     /locus_tag="ctg18_327"
                     /protein_end="382"
                     /protein_start="31"
                     /score="200.1"
                     /tool="antismash"
                     /translation="DIIDLGIGDPDLPTPKHIVDKLAEESQDPKNLKYPSFVGCPEFKQ
                     AVANFYQREYGVILDPDTEVLALIGSKEGIAHIVPTLVDPGDYVLIPDPSYPVYRMATL
                     LANGQYHNMPLTKENSFKPDFEAIPSEILGHSKLMFLNYPGNPTSATVDVSFFEKAVAF
                     GKKHNIPIAHDSAYNMVTFDFYKAPSILEVEGAKEIAVEFGSLSKTYSMTGFRIGYVVG
                     NKEIIKALSVLKSNTDTGQFTPIQKAAAYALNGNQSCVTEYNGIYKERMKAMLDGLKSI
                     GIKVDPPKGSFFIWAPVPNGYTSSEFVTSVLEQTGVIITPGTAFGPSGEGYFRVSLSVP
                     TERLYEAVNRI"
     CDS             19204..20685
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017:aldehyde dehydrogenase (Score: 527.9; E-value:
                     2.9e-160)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_328"
                     /transl_table=11
                     /translation="MQKILNYINGEWCESASGKFVPVLNPATGGVLAEVTQSTKEDVDR
                     AVQAAREAQKSWRLVPAPERAEILYKVAYLLKERKEQLAQVLTSEMGKVIAEGRGEVQE
                     AIDMAFYMAGEGRRLFGDTIPSELRNKFAMSVRVPIGVAGLITPWNFPIAIASWKSLPA
                     LVSGNAVVWKPATETPMVAAEFVKIYEEAGLPKGLINLVNGSGSEVGNAMVDHPGIDLI
                     SFTGSNEVGAAINGRAGALLKRTSLEMGGKNAITVLEDADLDLAVEGILWGAFGTSGQR
                     CTATSRVIVHEDVKEALTEKLLARIGELKMGNGLDESVKVGPVINRSALERIHEYVKIG
                     QEEGATLLTGGQIATGKSLDEGNFYLPTIFTDVTPDMRIAKEEIFGPVVSIISVRSLEE
                     AIEVNNSVEFGLSSAIYTANVNRAFHAMRDLDTGIVYINAGTTGAEIHLPFGGTKGTGN
                     GHRDSGVAALDVYTEWKSVYVDYSGKLQRAQIDNY"
     PFAM_domain     19237..20634
                     /aSDomain="Aldedh"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00171.24"
                     /description="Aldehyde dehydrogenase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_328_0024"
                     /evalue="1.70E-179"
                     /label="ctg18_328"
                     /locus_tag="ctg18_328"
                     /protein_end="477"
                     /protein_start="11"
                     /score="597.3"
                     /tool="antismash"
                     /translation="WCESASGKFVPVLNPATGGVLAEVTQSTKEDVDRAVQAAREAQKS
                     WRLVPAPERAEILYKVAYLLKERKEQLAQVLTSEMGKVIAEGRGEVQEAIDMAFYMAGE
                     GRRLFGDTIPSELRNKFAMSVRVPIGVAGLITPWNFPIAIASWKSLPALVSGNAVVWKP
                     ATETPMVAAEFVKIYEEAGLPKGLINLVNGSGSEVGNAMVDHPGIDLISFTGSNEVGAA
                     INGRAGALLKRTSLEMGGKNAITVLEDADLDLAVEGILWGAFGTSGQRCTATSRVIVHE
                     DVKEALTEKLLARIGELKMGNGLDESVKVGPVINRSALERIHEYVKIGQEEGATLLTGG
                     QIATGKSLDEGNFYLPTIFTDVTPDMRIAKEEIFGPVVSIISVRSLEEAIEVNNSVEFG
                     LSSAIYTANVNRAFHAMRDLDTGIVYINAGTTGAEIHLPFGGTKGTGNGHRDSGVAALD
                     VYTEWKSV"
ORIGIN
        1 tttactgacc aatttatatc gcgggttaac cattatggac ggagttggcg gctattcgaa
       61 tgatcagcgt gatgtactca ttactgtgat ttcgagatac gaattaaatg aagtgaaaca
      121 tcttattagt gaagttgatg caggtgcctt tgtcaatata acgaaaactc tggaagtaat
      181 gggcttattt catcgtccgg ctccaaaata acgtaaaaat attaacaaat tattctgaaa
      241 tttgttatac ttagaaaagc tacttttcta aggggtgaga acatgcgccc gattattatt
      301 gggatttttg cagctttctt ctttgcgttt acatttgttt taaatagggc gatggattta
      361 gcgggaggaa gctggatctg gagtgcttca cttcgttatt tttttatgat tccatttctt
      421 tttcttattg tcatggcgag aaaaaatctg aaggaattat ggcttgaaat gaaacaacag
      481 ccttataaat ggtttgtatg gagttcaatt ggttttggcc tgttttatgc gccgctttgt
      541 ttttcggcag cttttgcgcc cggatggtta attgcggcca catggcaaat aacaatcatc
      601 tctggctcac ttttagcacc attattttat gaaatagtca tgacttcaaa aggtcccgcc
      661 ctaagaaaag gtaaaatccc ttttagaggt atggcaatgt caatgattat tctgctagga
      721 attattctga tgcaattgca gcaggctagc agactatcgc tattggagat ttccctagga
      781 attgtacccg taatcgttgc ttcttttgct tacccgcttg ggaaccgaaa aatgatggat
      841 gtatgcggtg ggcgcttaga tgtttttcaa cgagtactag gaatgacgct ggcaagtatg
      901 ccattttgga ttgttttatc gctttatggt ttctttacgg ttggtttgcc tagtattgat
      961 caaacagttc aatcgagttt agtagcggta tcatcaggtg taatcgcaac agtgcttttc
     1021 tttcaggcta cagatcttgt caggggaaat atgcagaagt tagcggctgt agaggccaca
     1081 caatctttgg aggtattatt tgcccttttg ggagagatag tattgttaaa ctcggtgttc
     1141 ccatcgtctc tttcctgggc tggaatggtg ctggtgatgg ccggtatgat tctacatagt
     1201 tattcttccc accgccaaaa acatacaatt aaaccagttg aaaaatcctt atcaagctaa
     1261 agataaggat ttttttctgg aatttgtaaa gaatatcaaa aaacattcaa atagtttgaa
     1321 ttgttcacaa taatgtcaca attatcaggt ttattatttg tctttcgtgc tataatgaaa
     1381 ttgtaaaaga taaagaaaga aaaaataaca tcttaggagg ctcaaccata cgtgttcgtt
     1441 ccgttagtga acgagtagta aggttattct tgaaaagttt aacaggagaa gcagtctctt
     1501 agaaaaagag taaatcttaa tcaatccttc aaaattaact tgatgcaagc attaagatta
     1561 attgcgaagc aagctaatta agaaaagtaa atcttaatta gctagaaaga ttactgatta
     1621 caaggtgagg aactggagaa agtaaaccag tatactatac ctaaactttt tcaaaggagg
     1681 ccaagtgagg aaccctaaaa ccaagtaagg aaaagagtct caaatcggtg ctaaaccaaa
     1741 tatgtttcta ataataggag tttgaattcc atttaacatg tgaattaatt cctttttaac
     1801 ggaacaacac acatcggctg aatgattcaa aatgttcctt cattagatgc aaatctaaaa
     1861 agaacaaagt gtgaatcaaa aatttggctg atgtaaatgg ttgggtctcc taagatgtta
     1921 attattaagg ggctgcttca ataatgaagt agttcctttt tatttcctca tttttcgtga
     1981 atatgtttgt taaatattga aaaaataata gtagaagggg gtgaagcaaa atggaaaaaa
     2041 gaaaaagtca aaaaaataac gaccccgcac ttgcgcctgg aattaatgac ctagaggaat
     2101 tacaaaaaag tgcttcagaa gaagagataa ataatggcga gtacacgcat gttattacgc
     2161 taaaacttga tgatgctgat ccaagctaag catgacaaat catatcggtt tttgtcggat
     2221 ggtgcgcttc cctaggaaat aaattctgaa gtatcagatt attaaataaa aaagatggca
     2281 tctgttaaca acgccatctt tgcttttaaa agagaagctc gtatacctcg ttaagttcgt
     2341 ataaccgttt atcatcctga acatcttgtg cataactaat ttctgcttcc atcaccctat
     2401 ttagaaaatc aatttctttc ggattgaggc tcctgacaaa gttttcttca gatttataat
     2461 ttcctttcac caatttgtga taaatctgat gaccttcagt atgaccatct gtatagttgg
     2521 atagtgtttc tctcaagtat agcaatgttt tatccattgt gctcacccat cctttctaat
     2581 aataattttc ttcttaacag gatatttatt caccctatat attgcatgtg gtgatgcaaa
     2641 gattaccaga gaggttggag gaatttgagc tagaatggaa tagggacttt gcttacctct
     2701 aaatttttgt acatgtaaag attctatggc ttaaaatatc atgatacttt actaacatgt
     2761 taccgtgctg atttaaaata ctaaacaact ctggttcaaa attttgagag aagttaaatt
     2821 cctgtgctgt gtttccattc attaaatctg attgaagctg ccttatgtca atttctttaa
     2881 aaccgcttgc ttgtaaaagc gtacgccaat ctgattctaa cagtaaggaa tcaatattat
     2941 aaaattccat aatttcgcgc ttagcatcct ctggaaggct actgttgatt gtcatttcat
     3001 tcgctaaaag acgaccccca gtttttaata ccctgtaaaa ttcatgtaaa gcctgcggtt
     3061 tatttacgaa agctaaaact gattcacata atatgaactc aaaggagtca tctggaaaag
     3121 gaatatcttc cacagagcct tggactaatt gaatagggta ttttaatagc tgaaagcgat
     3181 tttttgcttt ttcaaccata atcgggttga gctcaaggca aacaatattg gcttgatatc
     3241 gttcatacat aaatgctgca gtctgccctg tgccacagcc ggcatctaat atggaagaat
     3301 tggaggagat tttttcttga gatagtacgt ttttggttag atttatccca ccaggatgtg
     3361 caccgccaac accaaatttg gccaggaaat caatatatgt taaaccaccc atagacacca
     3421 tcctcatttc ttttttgcat cttatgataa tacttcactg taggtgcgat agttattgca
     3481 aaattagtta ttaataataa cattatgtta actaaataat gattgaaaaa gttaacactt
     3541 atatctcttt actaagcgag catattaaga aaatggaaga tttctttatc ttcctaacga
     3601 tgtaagaaaa aggggtgctg aaggatgcgc aacatgagaa aatcggttat aaaaatgttt
     3661 agaccgaaac ggagaaataa tggagctatt tgggcctctc ttgctagtat tggaataggg
     3721 gcagccgttt atggaatgac aagggggaaa caaaataatc aggcacttcc cttaacagac
     3781 acgatgagga atcttgctag tccactgaag gaaactgtaa aaaatattgt tccaaaaatg
     3841 aatataggca aaatgaatac cgcacaatta gcagagtttt ccgaagacct aatgaatggt
     3901 gctttacaca atcaaaaatc aaaataagta aaaagtccgc ttgtcagcgg acttttttac
     3961 tatattctta tttaggtggt ggtggaatat ttttcggctt gtactgtatt ccatctgagg
     4021 aataaaggtt gataatgagt aaacttccca ttgtgcgcgc ccgtattaat atcggctgct
     4081 ggtatttatt tttgaataca aaatcagggc cgtaccagct aacggttgca tctcttccag
     4141 gggggatata agatacatct ttactatgtg aaaatcgttg aataattgcg agacctgcat
     4201 tatcaacagc attgaaaaga gttgatgata cttgacaaat tccgccgcca atatcttctg
     4261 aatattcccc tttgacgatg acaggtgctt ttaagtatcc tttttgcttt gttcgtttac
     4321 caactacttt attaaaggaa aagatctcat tgggaaacac aacataatta ttgatggctt
     4381 ctgcagctaa tttaatatta aaagacctat ttttatttcc cgggttaaaa gacgtgacat
     4441 accgtccaat tcgtaccgtc cggatattgc taagtaattc gctatcaact ttagggtagg
     4501 cagtattcat gggaatctca agagttggct tgttattttg ataaaaaatg gaataaagtt
     4561 cttttgcaaa tgcttcttta ttgatttcac ttcccggttt ttctggaata atctggcctt
     4621 tattatttat ataggcattt ttgggttcag tagatacttg ctgattcaac tgataaagaa
     4681 agcggttgaa tttcttgtta ttcataatcg gcaaatctga ataaggatga aaaaaatcgt
     4741 agcggttaat ggttgtcagc gatacaccgt cttttgtaat ggctatatca ttagcctcgt
     4801 taacggggtg ggcagccagg aaaattgtca aaatccatga aagttttaac ataagaaagc
     4861 acctccttat gttaatatag gcaatttact gttgtttcat gtaattgctg aaatgccttg
     4921 agaaacagtg agttctgagg ggtttgaata ttaaaaaaac ttttgtataa tgatattatt
     4981 cagtgtatct tccttacaga agaagtacaa aggtgatggt tattataata aatgggaatg
     5041 tgaggctgta atagtggggg aaattaaaat ggaacatgaa atacaagtga ttgcacggtt
     5101 tagtgaaacg gatgcgcttg gtcatattaa taacactagc tactttattt atctagaaga
     5161 agcacgaatc cgttttttgg aaatgttagg attcgattta aacggtcaga attttagttt
     5221 tatattggca tctgcaaaat gtgactatat tagtcaaggc tttttcaatc agcagttacg
     5281 gattacaaca tatgtaacaa aaattggtac aaaaagcttt cagcttgaac atgatattat
     5341 taacaaagat actaatcagt tgattgcaca tggccaggta gtaatggtat attttgattt
     5401 tgaaaagcaa caaagtaaac cactgcctga attgatgaaa caaggactaa atacgtactt
     5461 agtccattta taagctgttt tcgtaagatg aaactgcata gttttaaaca tttggccttg
     5521 gatcacaagg tcttttttac atttaaacaa aataacaaga ttggtggaga tactaagcaa
     5581 attaagacta atctattaaa aagttcgtaa caatttggat atatctttgc tatcacaaaa
     5641 aattcgatta cacttgtagt atggagtttt tttataggag tggagtaaca ttgaagatat
     5701 tagtgattga agataacaag agtgtttgtt caatgataga aatgtttttt gccaaggagg
     5761 gtattgaggg tgtatttgtc aatgacggtc ttgaaggata tcaacgcttt aaaagtggga
     5821 catgggatgc actaatcgtt gactggatgc tgccaggact tgacggtgta accatttgcc
     5881 gaagaattag ggaagaacag tatagtgtgc cgattattat gctaaccgcg aaagatagtg
     5941 aatctgatca agtactaggt cttgaaatgg gagctgatga ttatgtaact aagcctttca
     6001 gtccgctaac actgatggcg cggattaagg cagttacacg acgatatcaa aatcaagttc
     6061 ccaaagaatt ggacgggtta ttacagacag agcattttaa aataaataaa accacaaggg
     6121 aggtatatgt tgatggagtg ccaattacaa acttaacccc taaggaattt gacttattat
     6181 tctatctggt tgaacatccg cggcaggttt tttcaaggga acagctgtta gaaagtgttt
     6241 ggggctacca attttatggt gatgaacgga ctgttgatgt tcatataaag cggttgcgaa
     6301 aaaagctaga aaccgtgtcg caatttttcc atactgtatg gggagtaggg tataagttcg
     6361 atgacacaac gaaagccgat gaaatttaaa tatttttacc aacaattttt cagtcatatc
     6421 agtattatta ttgtggcatt tctattattg agtctgctgt ttgcccatta tcttgaaaat
     6481 cttgtttatg aaaataaaac ggacgagttg atttcatacg gaaaagcgat cttggcagaa
     6541 attaaagaag atccgctgcg aacagaggat gtagtgaaac aatacagcga tgtattggcc
     6601 gctagaaaaa tgagttttag catgtttgat caagacggaa atctttattt tgttaataat
     6661 caagggccgg caatcaagaa tctgccgcgt tctgattggc aaaagcttac gaagggacag
     6721 accatcgtcg ttcaaagcga ctataaacga tttgatcaag atggtgttac ttttgttgta
     6781 ctgccttacc tgtatcaaga taaattcttt ggcggaatct tattaacttc acccattagc
     6841 ggatcaatta agatgattca tgagatcaat aaaattttgt tgtcgacgat tttaatagca
     6901 tttggtgttt ccttcttaca gagttggttc ctgtcacaaa tacatgtgcg gcggattcaa
     6961 cgattgcgtg atgcaacatc aagtgtttcc gcagggaact acaacgtcca tgttcattcc
     7021 tccaattacg atgaaatagg ggaattagcg agcgatttta acaacatggt tgatacgatt
     7081 aatgcttcga tgctggaaat tgaaagcttg gaaaaccgca ggcgccagtt tatggccgac
     7141 gtttcgcatg agatgcgtac accgctaacc accatcagcg gcgtgataga agggttaaaa
     7201 aataacatga ttcccgaaga agataaggaa aaaggtatta accttgtcag ccaagaggct
     7261 aaacgattga ttcggcttgt aaatgaaaat ctagattatg aaaaaattcg ctccaatcaa
     7321 attcgcttat ttaaagaaga cattcagctg acggaagtgc tggagattat tcaagagcag
     7381 ttaagtttac aggctgaaga gaagaataat caacttattg ttgaggcttc acctgaggtt
     7441 tatgtctttg ctgattatga ccgcttggtg caaatcttaa taaatattac gaaaaatagc
     7501 attcaattta cttccgacgg aacaatttgg ctgcgagggc aagcggaggg aaatcatgtg
     7561 atcatcgaag ttgaggatac agggattgga attgatgcta gcgaagttga aaatatttgg
     7621 cgacgttttt ataaggctga tttatcgcga acgagtaatc cttatgggga gtttggctta
     7681 gggttatcga ttgttaaaca attagttcag cttcataacg gggaaatcaa tgtcacaagc
     7741 gaaaaaggga aagggacaaa atttgtcatt cgttttccaa agaagtgact taatggcaaa
     7801 gctgcaggaa ttagtcttgc agctttttaa tataacccta ataatttttt caaatgctga
     7861 ttaaaaattg ttcatagttt tttaatattt gttcgataaa gtaagagcag agattaattt
     7921 aagagaaaca gctataagga gttgtttaat atggacaata aagaaccgtt ggatcaagaa
     7981 acttcgattg atgtttccat accagctaaa acaactgttg ataataagga cataacgaat
     8041 gaaacgattc aaagcgaaaa tcatgagcca caaatctgtt cacaggagga agaaagcaag
     8101 caagaatcac ctaattcaga tttgaataca tcacaaactg taacagcagg caacaattta
     8161 aaaaatagct atgggacgaa gaagaaaatc aaaggggcgg catcgactat cgcagcaggt
     8221 gttatcggtt cggtgcttac actggcgata ttacctcata cgaactatgt aaagaacttt
     8281 caagggtccg aagcaccggc agtagctcaa gcagaacaag tcagcggcca ggtaaaaccg
     8341 gtaaccacgc aaaagtcgag ttccaattct attgctgata ccgtcgaaaa actgtcaaag
     8401 acaattgtgg gtattgaaaa ttatcagcaa cagcaaagta tcgacttttt cgggaataaa
     8461 caatcctctc aaaacgtgga ggcaggctca ggatccgggg ttatttttca aaaaacgaat
     8521 ggctcagcct atgttgtgac caataatcat gttgttgaag gggcttctag gctggaagta
     8581 tctttatata atggttcaaa aacaagtgca acagttattg gaacagatgc gttaactgat
     8641 ttagcggtcc ttaaaattga tgataaaaat gttactgaca ctgcttcttt cggagattct
     8701 tccagcttgc ggccgggaga ccaagtatat gcaatcggca atccattagg ttcagaacta
     8761 tcaaggactg ttacgcaagg gattgttagt gcgactaatc gcagtatttc agtttcgaca
     8821 tcagcaggag actgggaaac aacggtaatt cagacggatg cggcaataaa tcctggaaat
     8881 agcggcggtg ctttaattaa taatcaaggt caagtcgtcg ggataaatag tatgaaaata
     8941 tctgaaaatg gggttgaagg tctaggcttc gcaataccaa gtaatgatgt gattccaata
     9001 gttaatcaac taataaaaaa tggtaagatt gaccgcccat atttaggggt tggcttggct
     9061 gacttagatg aagtttcccg tgtttactta gcagagcttc ctgataaagt tacccaaggt
     9121 gcattagtaa tgaatattga tgcgaactcc gccgctgcca aggcaggctt ccagccaaaa
     9181 gatgtgattg tatcaatgaa cggggaaaaa ataactaatt catctgattt acgtaaatat
     9241 ctgtatacaa aagcaaagat tggcgatgac atacgattta aggtgtatcg tgacggaaaa
     9301 cggattacgt taacagcaaa gctaacgaac aatcgtacaa attaaaaact tgtttatctt
     9361 tcattgttct gtcaggactt gctgggcgtc tcctgcttat ggtaaaaata aacagcaaga
     9421 gtatttttcg aaaaaagggt gatcaagttg aaagaagtag atgatcgaat aaaggaaaac
     9481 ttaaacatcc tctttgtcgg ttttaatccg agcatccgtt ccagtgaaac cggtcaccat
     9541 tttgcaaacc ctaataaccg tttttggcga atccttgttg aatcgggtct aacatcaaga
     9601 aaattttccc cggaagaaga tgacctttta ctggatttgg gctacgggat aacaaatatt
     9661 gtggcaagac caacaaaggc ggcagatgaa attacaaagc aagaatatat ggttggacga
     9721 aagattctaa tacaaaagat tacaaggttt cagccgaaaa taatttgtta tgttggcaaa
     9781 ggggtatatt tacaatttag cgggaaaaag acagctcctt ggggtgttca agaagaggcg
     9841 gtcgttccgg atacaattga ttttgttgcc ccgtcatcaa gcggattagt acggatgaag
     9901 cttgaagaga tggtagacat ttataaagaa cttagagagt taatagctta gaaataataa
     9961 tcgacggcag gagggccgtc gattaattgt agtacatctc ctagttgccg aatttctgtt
    10021 gatagtgggc aagagttagg agcggaaaaa tatagcgata gctatgataa tgaatataaa
    10081 aagcaccacc catgccttgg ccattcgggt agtccattgt ccagtcttcg tgcttgagag
    10141 atgatagtaa ataattcatt cctcgcgtaa tttcatttgt gggacggtct gatgcagata
    10201 gtaaagcatc caccacccac gctgtatgaa caaccgtact gctaccgagt ggaacatagc
    10261 ggttttggac atcactgtgg catgattctc cccaaccgcc atctttattt tgaatatttc
    10321 gtaaccaatt aattgccgta tcaatagatg aatcattatt agtcacgcca acggctcgca
    10381 gtccagtaat cgcagcccat gtcccgtata aataagaaat cccccagcgt ccataccaag
    10441 aaccatcctt ttcctgcttc ttttttatcc atcttattcc ttttttgatg acaggatgat
    10501 tttctgatag atttgtataa tgtccaaaaa attctagagt tctgcctgtt aagtcggcac
    10561 aagacggatc caacagtagg aacttcgctt tatcaagcgg aagccattct aacagcttgg
    10621 aatcggtatt tttttcgaaa gccggccagc cgccatcggc gttttgcatc gacagagtcc
    10681 agctgatgcc gcgttcccat gcgacgtttt ccggaggaac gatgcgagaa atcgagcgta
    10741 aagccgctgt tgtatcgtca acatcgggta cgaacgtatt aatatcagaa aaaccccacc
    10801 cacctggcag gctggttgga ttatggacca cccagtctcc aaaacgctgc tgttgtctgc
    10861 tcaatagata ttgatgggac ttggccacca ttgggtcttt tgatgataca ccagcaaatt
    10921 gtaaagcatg agttataagt gccgtgttcc aaacattagc ggttgtgtat tgcatatgtg
    10981 gaagtccatt aatctcacat ttcatagact ttaaaccagc gattgcctga gtgatgacgt
    11041 ggtctgtttt tttatatcca agtgcaagca gggcaaaaat cattaaaaat gtagagctgt
    11101 agtaactgca caacgtacca tttacttcaa tcctttcaag catgtatttt tttccgcgtt
    11161 caagcgctaa acttcggagt tcttcgggaa ggccgactaa gtttttgact ccttccttaa
    11221 tcaatgataa tagtgagcgc cattcctctg agcgtatcca cggatcttct atgtttcggt
    11281 gggtgactaa gtcagttaaa actggggatt tgacggtttt gagtgaatag tttttggcag
    11341 cgagtatcat aatgggcgtt agattagctc ttccaaaaat cgaaaatgaa aagaaattaa
    11401 taggaaaaat tggtgggagt aatatcattt caatcggtaa tggggaatgg tttggccact
    11461 tatattgtcc cgtaatggcg agcatgattt tggtaaatat actgactgct tcaattcctc
    11521 cgtttgtttt aataaatttc ttggcaagct cgagccgctt atctgtttta ctataataac
    11581 cggaatagag cagcgcatag taagcctcca atgtggcagt aacatttccc tttccttcat
    11641 cgtaaaatag cttccaggta ccatatcttg tttgcttgct aaggattctc ttgcatagac
    11701 ctttaattaa ttcctcctca tctatctcta ggctccgtaa taaaataatc atatacgcat
    11761 ctgtggatat ccccgtatca aatggataat tccaagaacc atcatgagac tgatcattcc
    11821 ttaatgtttc aatgagccaa ttaatgcctt ccttcgtttc aaccacagat aatcatcctt
    11881 tctcatcgct aattaatcat aagttataca tattcccaaa ttgtaaggtc aattcttgaa
    11941 ggaggtgttt acaatttttt ttacacgagg ccggaaaatg tcaccgctgg aacatattcg
    12001 tgctgaattg cggcaaaaga gcaaaggccc agcatccact ccacatgact taacagttca
    12061 agaacggcgg ctgttggaaa aaatccgcag aaaaacagag gaaagcaata gtaataatat
    12121 tacgcggaca aaggcatacc tggattttta tttgcgctat cctgatatcc attgggcctt
    12181 tttaggacat atggtttcgc gaaatggcgg ctggaatatg actgatttgc agggggaatt
    12241 cttgccacga ttattatctg aaaaagaacg gaagtctttc tatcactttt tggaacgagg
    12301 aaattggctc atctttcaag atgcttttcc gcaatttttg atttacgaag aaagtttaca
    12361 gcagcaaaaa ccattgtttc atttgtttcc attcttaaat gtttccactt ttatggagac
    12421 ggtttggaac cattattgga aacagcctga tcattatcta ctttgtatgg cacttattat
    12481 taatgaacaa cactatttgg agcaaagggt aattcggcag ccactatatc aaaaagaagt
    12541 gctgcatcaa tttaaatttt tcctgcagga tttgctgtca tttaatcata ttctctttcc
    12601 ctatgaaaat ggaaaactgg caggacaaac aatgcatcaa tttgagtcgt tacacgagcg
    12661 aatattactc gggaaaaggt tatattctgt cctctttgct aataaagatt ttttaagaca
    12721 agttattgat tgggcaaaac gccatccaca tacgggatcg agaaaagatt attggccaca
    12781 tctctttaat gacgtgaagg aaggggggcc gggcattact tacccactcc ggctaaagtc
    12841 ctgtcgactt cgaaaagggg caaagcgatt gtatagtcca cgacttgaat atgcctggaa
    12901 gaatgttgtt cagcaagaag cggagaaagg ggattggttt acaaatgagg atgtagcaaa
    12961 ttacttagtg gatgatacga aaaacataga tagggagatt aagcatgaat actgtaaaac
    13021 actcgaacga ctcgagattg cagccgtggc gaaaaagacg attaactttt tgggatagaa
    13081 gataccttcc tgctgcacta ttggctgggt tagtcggaac ctattctgac ctattgtttg
    13141 tgggtatggg tctgtacgaa tttccacttc ggccgtttcc gcaaatcttc ccgataaata
    13201 ttgtatttac cctcggtgtc ctgccgctat gtgtgatgat ctttttgtat tatggctcgc
    13261 aggtaactaa gtggggcaaa ttggggatta ttttatttat tagtctgtta gtaccgattt
    13321 tggaaaagct ggcggagcaa ctaggttatt ttgtgcattc agaaaattgg cagcatattt
    13381 attcattttt cgggtatttg ttttttctta tatggattga tcactttaat cattgggtaa
    13441 aaagtagaaa aagccgtgcc taaaatcacg gctttatttc tatagtgggg aggctctgtc
    13501 cgtccgtaca gtggttaagt gtcccgcaac aagcgaaatg tgcggacaga gcctctacac
    13561 ttattttatc ataaattggt tggaattatg ctcaagagaa tataattact ttcctttcta
    13621 tttcgaaaag tgtatgatta taatgatttt acataagtaa ggagttgttt ataatggcaa
    13681 aaaaaggata catagtaatg gaaaatggag aaaagattga atttgattta ttcccgaatg
    13741 aggctcctgg aacagtggct aattttgaaa aattagctaa tgaaggtttt tataatgggg
    13801 ttatctttca ccgtgtcatt ccaggctttg taagccaagg gggagaccca actggaactg
    13861 gtatgggtgg tccaggatat accattaaat gtgaaacgga aggcaatcct cataagcatg
    13921 ttcctggtgc gctttcgatg gctcatgcag gcagagatac agggggaagc cagttcttta
    13981 tcgttcatga atcacagccg catctagatg gagtacatac cgtatttgga caagtgactt
    14041 caggtttaga tacagtaaaa gcaatgagaa atggcgataa gatggttgaa gtaaaggttt
    14101 ttgatgaaga ataataaaga ttttcaggga gctttttatg agctctcttt ttttaggtca
    14161 tgcaaatact ttaatataat ttctattatt gatacaatga tttctatcaa actattgatt
    14221 agatgaggat tgcctatgaa actgatatct tggaatgtaa acggcttgcg ggcgtgtgta
    14281 aaaaaaggat ttttagattt ctttcatgaa atcgatgcag atattttctg catccaggaa
    14341 acaaaattgc aagaaggaca gattcaactt gagttggacg gctattatca atattggaat
    14401 tatgctgtca agaagggata ttcgggaaca gctgtattta ctaaggtaga gccaatttct
    14461 gtccgctatg gtgtaggggt agaggagagt gaggacgaag gaagaattct aacgttagag
    14521 tttgcggaat tcttcctagt gaatgtctac acgcccaact cacagcgtga tttggcaaga
    14581 ttaggctacc gccttcagtg ggaggaccgt atcagaaaat atttgcagga actggatgag
    14641 caaaagccgg tcattttatg tggtgattta aatgtagccc ataaggaaat agacttgcgg
    14701 aatgctaaaa ccaatatcgg gaattccggg tttaccgatg aggaacgtga aaaaatgaca
    14761 atgctgcttc aatcggggtt tattgatagt ttccgatatt tttatccgga aaaagaaggt
    14821 gcctatacat ggtggtctta tatgaataag gttagggagc ggaatatcgg ctggcgtatc
    14881 gattatttta ttgtttcgca gtctctaaca aataggttaa aaaatgcaga aatatatgct
    14941 gatatcatgg gcagtgatca ttgcccagtt atgcttgaaa tttgttaaaa tagtttaata
    15001 agaaggccct ttgcaaagaa gattatactc atgcaaaggg ctctttctat agttgattaa
    15061 gtgcagttcc taattcatcg aattctggaa ggcgattggt ctcgataatg ggcttgtttt
    15121 gctcttgaac atcttgatca aaattttcat tagcctcgct gattctttta gatggcacgc
    15181 ttacatctcc tttaaacagg aattatacag gtatagttta tccttaatta attttcataa
    15241 acaaaaggga tgttccaaat ctatgtaaaa aatactaata ctaacttctg cgaaatctcc
    15301 ccatcaccgc aattgccttg gtaatataaa caaaggcagt aggatcaact tttttaatag
    15361 cttctttcgt ctccgttaat tcgtatttag tgataacggt tgttaacact tttttatgtt
    15421 gatgagaata aaccccttca gcatcactca ttgttacccc acgtgaatgg agttgaatta
    15481 attccttact taattgctcc catctttccg ttataattga tacagctagt ttagtttgat
    15541 ttgtataaac tgtgtcaact gcttttcccg aagcaaaaat ggcaaaaaga gtatatagag
    15601 tagaatctgc accaaatact aatgatgaga ttaggacaat aatgaaattt acacatgtat
    15661 ttagatagcc gacagaaagg tcctttttct ttgataaaat caaactaata atgtctgtcc
    15721 cgccacctga tccgcctaaa cggataatgg taccaatgct aattccgttt atcactccgc
    15781 cgaatacact tgataacaag aaatcattac tgaattcttg aacaggtata attttcatcg
    15841 acaccgataa aagcacaaca gagtatacag ttaaaaacat aaactttctt cctaaataaa
    15901 aataacccaa gataagtaac gggatattta aaattagaat gatccatcca gtgtttattg
    15961 ctaaaaaatg gtgaatgatc atagctactc cggcaatacc acctgttaag accttatgcg
    16021 gaatcagaaa agtattcatg gagtaggcca ttgaaatagt aaaaaaagtg atagcaataa
    16081 gttgtaaagc tgtttttttc atataatgac acctctaaat tgttaacctt aaaccttcca
    16141 ttttgtagtg taatgtttat tacatcaatt gactagagaa atatttgtga aaaatattag
    16201 accgtttggc ttaatcgcta cattttttat gtgaaaaatg aagtatttta agcaaaaatt
    16261 actgttgacg aatcgaaaca ctggtagtat gattattaat gttctctttg gggacatgat
    16321 ttagaacttg atattttttg tttttgaaaa aagtatctga cctctttttc tttgtatatg
    16381 cgggtgtggc ggaatcggca gacgcgctag attcaggttc tagtggtagt aataccgtat
    16441 gggttcaagt cccttcaccc gcatcattaa tatgcggaag tagttcagtg gtagaacacc
    16501 accttgccaa ggtgggggtc gcgggttcga atcccgtctt ccgctccatt tctctaacgg
    16561 gaaatagctc agcttggtag agcaccacgt tcgggacgtg ggggtcgcag gttcaaatcc
    16621 tgttttcccg actgtttagg gtttcagcct agatggaggg tttctctttc acatttagca
    16681 ggtcaacagt tttcatttcg ttaggtaatt atttttatat caatatttgg cggtgtagct
    16741 cagctggcta gagcgtacgg ttcatacccg taaggtcggg ggttcgatcc cctccgccgc
    16801 taccatatga ttatggagga atacccaagt ccggctgaag ggatcggtct tgaaaaccga
    16861 caggcgggtt aaaccgcgcg ggggttcgaa tccctcttcc tccgtttttt attatggagg
    16921 ggtagcgaag tggctaaacg cggcggactg taaatccgct ccctcagggt tcggcggttc
    16981 gaatccgtcc ccctccatta attttcaggt taatatagac ttcaattact gacgttttcc
    17041 aattatatgg aaaacgtttt ttgtattaaa aaaaatacat tcgaattctt ttttatttaa
    17101 tatttacctt acctattatt ggtattttac ctggattacg ttaatataaa gtaaagtaga
    17161 ggggaaaggg aggaaaagaa ggatgaaagt attaattgtt ggtgcaaatg gaatgttggg
    17221 aagccagatt gttgaagaat taaaagatga gtttgaactc attcgagcaa gcaggcagaa
    17281 ctcagacatc aaggttgata ttacttcacc acaaagcatc aagaaaatgt ttgaaacagt
    17341 gggtaagata gatgccttaa ttagtgctgc tggatcgact cattttggat caattgaatc
    17401 aatgacaccg gaattaaacg cagtatcatt aaataacaaa ttagctggcc aaattaatct
    17461 cgtattatta ggattggatt acataaacga caatggcagc atcaccctta ctagcggggt
    17521 tctcatggat gatccagtta aggatggagc ctctgcagct atggcaaatg gaggaatcaa
    17581 agcgtttgta aaagcggctg ctttggatat gccaagagga atcaggttaa ataacgtaag
    17641 cccaacgata ttagaagaat ctgctgacca atatggtgaa ctatttaaag gtttcctgcc
    17701 agtgccagga aaacgtgtcg cacttgccta cagaaaaagt ttacaaggcg ggcaaacagg
    17761 gcaaacctat gaaatatatt aatgatggaa tactgtagaa agtgtttggg gttcaaactc
    17821 cagacacttt tttattttaa cggagaggtc tctttgtaaa aatcatacgg aaagaatagt
    17881 aaaatctatt ttatttttgt ataaatcaac catagtgatt attttgaaaa atcgataaat
    17941 ttaaaatatg gaaattaaaa ctttctcaat aataatttca ttttagaaat aaaggcgggt
    18001 gagtgcgtga actttacatc taatcgtgtc ggtcaaattc ccccctattt atttgcagaa
    18061 atcaataaga aaaaagcaga aatgttaaag gcgggcatcg atattattga cctaggaatt
    18121 ggtgatccag atcttccaac accaaaacac atagtcgata aattagcgga ggaatcacag
    18181 gatccgaaaa atttaaaata tccaagcttt gttggttgtc cagaatttaa acaggcagta
    18241 gctaattttt atcagcgaga atatggggta attttagatc ctgatacaga ggtattagca
    18301 ttaattggtt ctaaagaagg gattgctcac attgtaccaa cgttggttga tccaggagat
    18361 tatgtattaa tccctgatcc aagttatcca gtataccgca tggctacgct attggcaaat
    18421 ggtcagtatc ataacatgcc gttaacaaag gaaaacagct tcaagccaga ttttgaagct
    18481 attcctagtg aaatccttgg gcactccaag ctaatgtttt taaattatcc gggaaatcca
    18541 acatcagcaa cagtcgacgt ttcctttttt gagaaggcgg ttgcatttgg aaaaaaacat
    18601 aatatcccaa ttgcccatga ttctgcttat aatatggtaa cctttgattt ttacaaagct
    18661 cctagtattc tagaagtcga aggggccaag gaaatagccg ttgaatttgg ctctctatcc
    18721 aagacctata gtatgactgg ttttcgaatt ggctatgtgg tagggaacaa ggaaataatc
    18781 aaagccctct cggtattaaa aagtaataca gacacaggac aattcacacc gattcaaaaa
    18841 gcagcagctt atgccttaaa tggcaatcag agttgtgtga ccgaatacaa tggaatctat
    18901 aaagagcgca tgaaagcgat gttggacggg ctcaaatcaa ttggaattaa agtagacccg
    18961 ccaaaaggca gctttttcat atgggcaccg gttccaaatg gatatacgtc tagcgaattt
    19021 gtgacaagcg tactagaaca aacgggtgtc attattaccc ctggaacagc ctttggacca
    19081 tctggggagg gatattttcg cgtttcccta tcggtaccaa cggagcgact gtatgaagca
    19141 gtaaatcgaa ttaaagaaaa attaaaaatt gtgatgagtt aactagaatt ggagggtttt
    19201 attatgcaga aaattttaaa ctatattaat ggtgaatggt gtgaatcagc ttcgggaaaa
    19261 tttgttcctg ttttgaaccc cgcgactgga ggggtacttg cggaagtcac gcaatctact
    19321 aaggaagatg ttgaccgcgc tgtccaagca gcaagagaag cacaaaaatc atggcgtttg
    19381 gttcctgctc ctgaacgggc agaaattctc tataaagtag catatctgct taaggagcga
    19441 aaagagcagc ttgctcaagt attaacaagc gaaatgggta aggtaatcgc tgaaggccgc
    19501 ggcgaggtac aagaagcaat agatatggct ttttatatgg caggagaagg gcgtcgatta
    19561 tttggtgaca cgattccttc agagttacgt aacaaatttg cgatgagtgt ccgcgttcct
    19621 atcggagtcg caggtctaat taccccttgg aatttcccaa ttgctatcgc ttcttggaaa
    19681 tcactccctg ctcttgtatc tgggaatgca gtagtctgga aaccggcaac cgaaacacca
    19741 atggtagcag cggaattcgt gaaaatctat gaagaagcag gtctgccaaa gggattaatc
    19801 aatcttgtaa atggctctgg tagcgaagtt ggaaatgcaa tggtagacca tccgggaatt
    19861 gatcttattt catttaccgg gtctaatgaa gttggtgcag cgattaatgg tcgtgccggt
    19921 gcattattaa agcggacatc tttggaaatg ggcggaaaga atgcaattac tgttttagaa
    19981 gatgctgacc ttgacctagc agtagagggc atattatggg gtgcattcgg aactagtggt
    20041 caaagatgta ctgcgacaag ccgtgtaatt gtccacgaag atgtaaaaga agctttgaca
    20101 gaaaaattac ttgctcgaat tggcgagtta aaaatgggta atggtttaga tgagtcggtt
    20161 aaggttggtc cagttattaa ccgttctgca ctagagcgga ttcatgaata tgtaaagatt
    20221 ggtcaagagg aaggggcaac tctgctcacc ggaggtcaaa ttgctactgg taaaagccta
    20281 gatgagggta atttctactt gccaacaatt ttcacagatg ttactccaga catgagaatt
    20341 gccaaagaag aaatctttgg accagtagtc tcaattattt ctgttaggag tttagaagaa
    20401 gcaattgagg ttaacaatag tgtggaattt ggattatcga gtgcaattta cacggcaaat
    20461 gtaaaccgtg ccttccacgc tatgagggat cttgatactg gtatcgttta tatcaatgca
    20521 ggtacaaccg gtgccgaaat tcacctgcca tttggcggta caaagggaac aggcaatggc
    20581 cacagagatt ctggcgttgc agcgcttgat gtctatacag agtggaaatc tgtatatgta
    20641 gattatagcg ggaaattaca acgagcgcag attgataact attaatttaa taaactagtt
    20701 gaatacaaaa aggagtctaa gtagttagac tcctttttgt attctccaat aaaaaatgaa
    20761 ggcatttagg tgcgtcgcca agcacgtaag gaattattat taagcatatc atcagtactg
    20821 tgggggatag aagtctattc atacactctt ttataaatta atcagataaa tattaaaaat
    20881 attttgacta atctataaat tttagctata attacggtat tccatggtca gaccaaaacc
    20941 aaagggttct gtttaccagg ggttaaagtg ttaatggaca tggttttgca taattagtaa
    21001 aaagtgaggt ggtttaggtt gttaattgtt tatccagatg ccgatccgga agcaagggat
    21061 tggcttatgg atcatccact agcgaatgaa ctgaggaagc tagcggagtt tcggatttat
    21121 gttgggaggc ctgaatcaca taaagaatat gtgaaaaggg taaaggacgc ggatgggatt
    21181 ttattagggt ggggcatccc taatgaagta attactgaat gtcctaatct taaagttatt
    21241 tctttcactg ggattggtgc ttccaatttt gttgatttga aatatgcaga atctcgaggc
    21301 attatcgtta caaacacccc aggctatgca gataatacgg ttgcggaaca tgctcttgct
    21361 ttgctgctat cattaacaaa gaacattgtc cctaatcatc agaggttggc aaaaggtgtt
    21421 tgggatcaga gtcgcaactc agttgaacta agaggaaaaa caattgggct tatcgggctt
    21481 ggtggtatcg gaaaaagaat ggccgaacta tgtaaggcca ttggcatgaa cgttatttgt
    21541 tggacattta atccaacccc tgaccgggca caacaattgg gaataacgtt taccggttta
    21601 gaagagctcc tccaagaatc tgacgttgtt tcattacatc tcccatacac agaacaaaca
    21661 gcacatatgc ttagctacaa ggaattgtca ttgatgaaaa acgaggccat tctgattaat
    21721 acatcacgag ctcaattgat tgatacagac gccatggtta aatgcctgtt aacaggaagg
    21781 atttcggggg ccggaattga tgttttcgat gaagaaccaa ttataaagga tcatccacta
    21841 ctgtccttgc ctaatgtggt cttgag
//
