LOCUS       NZ_CP076401.1          20144 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP076401.1 Clostridioides difficile strain S-0253 chromosome,
            complete genome.
ACCESSION   NZ_CP076401
VERSION     NZ_CP076401.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 12:55:40
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 3053251
            Orig. end    :: 3073395
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..20144
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[3063251:3063395](-)"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10144)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..20144
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..20144
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="ranthipeptide"
                     /region_number="3"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /tool="antismash"
     CDS             complement(5615..7048)
                     /locus_tag="ctg1_2650"
                     /transl_table=11
                     /translation="MKSTLGVENNMKNSKKILAIGLTLFLVMVNTPMVNALTSVEQIKG
                     NDRYETAAKIADKQNYNTAILINSDNSLADGLSASGLAGALNAPILMTKQNQIPNTTME
                     RLNKAKTVYIIGSESTISKNVENQLLSKKKVVQRIFGENRFDTSIKIAEKIKEIKPIDK
                     VIIANGFTGEADAISASPVAARDGVPIILTDGNSVGFDTTGLKSYALGSSEIISDELVK
                     STNSIRLGGTDRFETNKIVIQEFYKNSKEFYLSKGLQLTDALAASTIAKNAPVVLVENG
                     SNKSILSGADKLTVLGGINQNVIKQCINQASPNQQGLYYNPNDRAFKERIKGKVYALTK
                     QYRKENGVRALSVASRLEGLANDWSNLMANKKTLSHTINGKNSYSTFLKYLDWSEIKPG
                     YIAVQGENIIKYKIPDKPVYTNRDADDIGNFIFNEWKTNPEEGTNMLHKGYEIMGFGIA
                     ITGDKNLYATHEFYGRYKE"
     PFAM_domain     complement(5657..6037)
                     /aSDomain="CAP"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00188.28"
                     /description="Cysteine-rich secretory protein family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2650_0085"
                     /evalue="8.30E-09"
                     /label="ctg1_2650"
                     /locus_tag="ctg1_2650"
                     /protein_end="464"
                     /protein_start="337"
                     /score="36.4"
                     /tool="antismash"
                     /translation="LTKQYRKENGVRALSVASRLEGLANDWSNLMANKKTLSHTINGKN
                     SYSTFLKYLDWSEIKPGYIAVQGENIIKYKIPDKPVYTNRDADDIGNFIFNEWKTNPEE
                     GTNMLHKGYEIMGFGIAITGDKN"
     PFAM_domain     complement(6152..6367)
                     /aSDomain="CW_binding_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04122.14"
                     /description="ell wall binding domain 2 (CWB2)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2650_0084"
                     /evalue="3.40E-10"
                     /label="ctg1_2650"
                     /locus_tag="ctg1_2650"
                     /protein_end="299"
                     /protein_start="227"
                     /score="40.5"
                     /tool="antismash"
                     /translation="RLGGTDRFETNKIVIQEFYKNSKEFYLSKGLQLTDALAASTIAKN
                     APVVLVENGSNKSILSGADKLTVLGGI"
     PFAM_domain     complement(6389..6637)
                     /aSDomain="CW_binding_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04122.14"
                     /description="ell wall binding domain 2 (CWB2)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2650_0083"
                     /evalue="7.90E-15"
                     /label="ctg1_2650"
                     /locus_tag="ctg1_2650"
                     /protein_end="220"
                     /protein_start="137"
                     /score="55.4"
                     /tool="antismash"
                     /translation="RIFGENRFDTSIKIAEKIKEIKPIDKVIIANGFTGEADAISASPV
                     AARDGVPIILTDGNSVGFDTTGLKSYALGSSEIISDEL"
     PFAM_domain     complement(6671..6922)
                     /aSDomain="CW_binding_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04122.14"
                     /description="ell wall binding domain 2 (CWB2)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2650_0082"
                     /evalue="1.10E-17"
                     /label="ctg1_2650"
                     /locus_tag="ctg1_2650"
                     /protein_end="126"
                     /protein_start="42"
                     /score="64.5"
                     /tool="antismash"
                     /translation="IKGNDRYETAAKIADKQNYNTAILINSDNSLADGLSASGLAGALN
                     APILMTKQNQIPNTTMERLNKAKTVYIIGSESTISKNVE"
     CDS             complement(7480..9375)
                     /locus_tag="ctg1_2651"
                     /transl_table=11
                     /translation="MLSNKKRSMAIVMAGATVMSAAAPIFADNTVTENVDKNYTVSAKD
                     SAKLIEEVRKALEVKFEDTKAGANVNDRVYDIKVDNVNLTNATQLQNKINSLTEGQSLK
                     VTIQDKGHQVLGGKVVDYKIENYKTAQEIVDAVNAYNATLAEDSDNKLTATIKSTNTVE
                     VKRAKDSANVITLNVGDQHLDFSKVITSEEGTFEGYEKSYSDIDSKELHTITVKNADLQ
                     DISAEELFDGIRLTTLGREIVNKVKNGYALTFENEAILTQEQEDSDDKDKPEKSSFDIV
                     LSKANEKPETISVSSKNHKLVRDLHKVLTDVKGGKELKVEVLSGDSRFTTAVEVSKERF
                     KDGEAEAIILVGEDAIVDGLASAPLASQKNAPILLSKKDSLPSEIEAEILRVLGSNLSS
                     KKIYIVGGESKVSKETEEKLSKLGVSKVERVSGEDRFETSLEIAKQLKDTFKTAFVVGG
                     NGEADAMSISARAAQFGAPIIVTGNELDANAEKLLKGKELEIVGGENSVSKEVEDKLVD
                     IDLNNKVERLAGENRKDTNAKVINKYYAGATKAYVAKDGYVGGNGQLVDALTAAPLAAS
                     SKAPIVLTTEELSKSQEEVVELRLKNATKLVQIGEGIAKNAIEKIAEKINLFTKN"
     PFAM_domain     complement(7606..7800)
                     /aSDomain="CW_binding_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04122.14"
                     /description="ell wall binding domain 2 (CWB2)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2651_0088"
                     /evalue="2.20E-10"
                     /label="ctg1_2651"
                     /locus_tag="ctg1_2651"
                     /protein_end="590"
                     /protein_start="525"
                     /score="41.1"
                     /tool="antismash"
                     /translation="RLAGENRKDTNAKVINKYYAGATKAYVAKDGYVGGNGQLVDALTA
                     APLAASSKAPIVLTTEELSK"
     PFAM_domain     complement(7840..8091)
                     /aSDomain="CW_binding_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04122.14"
                     /description="ell wall binding domain 2 (CWB2)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2651_0087"
                     /evalue="9.10E-16"
                     /label="ctg1_2651"
                     /locus_tag="ctg1_2651"
                     /protein_end="512"
                     /protein_start="428"
                     /score="58.4"
                     /tool="antismash"
                     /translation="RVSGEDRFETSLEIAKQLKDTFKTAFVVGGNGEADAMSISARAAQ
                     FGAPIIVTGNELDANAEKLLKGKELEIVGGENSVSKEVE"
     PFAM_domain     complement(8131..8409)
                     /aSDomain="CW_binding_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04122.14"
                     /description="ell wall binding domain 2 (CWB2)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2651_0086"
                     /evalue="8.10E-13"
                     /label="ctg1_2651"
                     /locus_tag="ctg1_2651"
                     /protein_end="415"
                     /protein_start="322"
                     /score="49.0"
                     /tool="antismash"
                     /translation="LSGDSRFTTAVEVSKERFKDGEAEAIILVGEDAIVDGLASAPLAS
                     QKNAPILLSKKDSLPSEIEAEILRVLGSNLSSKKIYIVGGESKVSKET"
     CDS             complement(10001..10144)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SCIFF"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR03973"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2652"
                     /sec_met_domain="TIGR03973 (E-value: 7.3e-24, bitscore:
                     81.1, seeds: 29, tool: rule-based-clusters)"
                     /sec_met_domain="SCIFF (E-value: 2.2e-24, bitscore: 82.8,
                     seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKHVKTLSQATLKQSAAKGGCGECQTSCQSACKTSCTVANQEC
                     ER"
     aSDomain        complement(10007..10135)
                     /aSDomain="TIGR03973"
                     /aSTool="tigrfam"
                     /description="six_Cys_in_45: six-cysteine peptide SCIFF"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2652_0024"
                     /evalue="9.10E-24"
                     /identifier="TIGR03973"
                     /label="ctg1_2652"
                     /locus_tag="ctg1_2652"
                     /protein_end="46"
                     /protein_start="3"
                     /score="81.1"
                     /tool="antismash"
                     /translation="KHVKTLSQATLKQSAAKGGCGECQTSCQSACKTSCTVANQECE"
     PFAM_domain     complement(10007..10135)
                     /aSDomain="SCIFF"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13165.8"
                     /description="Six-cysteine peptide SCIFF"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2652_0089"
                     /evalue="1.10E-23"
                     /label="ctg1_2652"
                     /locus_tag="ctg1_2652"
                     /protein_end="46"
                     /protein_start="3"
                     /score="83.0"
                     /tool="antismash"
                     /translation="KHVKTLSQATLKQSAAKGGCGECQTSCQSACKTSCTVANQECE"
     CDS             complement(10210..10572)
                     /locus_tag="ctg1_2653"
                     /transl_table=11
                     /translation="MGKSNYIFKGLGYAYIITLAVLLVYNLFLTFTDIGGDNITMVSSF
                     ITTISAAIGGFYTSKHMKEKGLMYGLLVGLLYIVCIFLTVFLAQEKFVFEVGMIYKLLL
                     ISAAGGIGGVLGVNFK"
     aSDomain        complement(10216..10557)
                     /aSDomain="TIGR04086"
                     /aSTool="tigrfam"
                     /description="TIGR04086_membr: putative membrane protein,
                     TIGR04086 family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2653_0025"
                     /evalue="3.40E-29"
                     /identifier="TIGR04086"
                     /label="ctg1_2653"
                     /locus_tag="ctg1_2653"
                     /protein_end="119"
                     /protein_start="5"
                     /score="99.3"
                     /tool="antismash"
                     /translation="YIFKGLGYAYIITLAVLLVYNLFLTFTDIGGDNITMVSSFITTIS
                     AAIGGFYTSKHMKEKGLMYGLLVGLLYIVCIFLTVFLAQEKFVFEVGMIYKLLLISAAG
                     GIGGVLGVNF"
     PFAM_domain     complement(10225..10557)
                     /aSDomain="DUF3792"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12670.9"
                     /description="Protein of unknown function (DUF3792)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2653_0090"
                     /evalue="4.20E-26"
                     /label="ctg1_2653"
                     /locus_tag="ctg1_2653"
                     /protein_end="116"
                     /protein_start="5"
                     /score="91.5"
                     /tool="antismash"
                     /translation="YIFKGLGYAYIITLAVLLVYNLFLTFTDIGGDNITMVSSFITTIS
                     AAIGGFYTSKHMKEKGLMYGLLVGLLYIVCIFLTVFLAQEKFVFEVGMIYKLLLISAAG
                     GIGGVLG"
     CDS             complement(10630..10923)
                     /locus_tag="ctg1_2654"
                     /transl_table=11
                     /translation="MPQQQIIMSIGLWVVVIAIFYFLMIRPQKKKDKQLKEMRSSLSVG
                     DKVITIGGIVANVAKVEDDVVILELGPNRTKVPFEKWAIGTVKSKKEEIEED"
     aSDomain        complement(10663..10890)
                     /aSDomain="TIGR00739"
                     /aSTool="tigrfam"
                     /description="yajC: preprotein translocase, YajC subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2654_0026"
                     /evalue="3.60E-24"
                     /identifier="TIGR00739"
                     /label="ctg1_2654"
                     /locus_tag="ctg1_2654"
                     /protein_end="87"
                     /protein_start="11"
                     /score="82.6"
                     /tool="antismash"
                     /translation="LWVVVIAIFYFLMIRPQKKKDKQLKEMRSSLSVGDKVITIGGIVA
                     NVAKVEDDVVILELGPNRTKVPFEKWAIGTV"
     PFAM_domain     complement(10669..10896)
                     /aSDomain="YajC"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02699.17"
                     /description="Preprotein translocase subunit"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2654_0091"
                     /evalue="7.70E-29"
                     /label="ctg1_2654"
                     /locus_tag="ctg1_2654"
                     /protein_end="85"
                     /protein_start="9"
                     /score="99.5"
                     /tool="antismash"
                     /translation="IGLWVVVIAIFYFLMIRPQKKKDKQLKEMRSSLSVGDKVITIGGI
                     VANVAKVEDDVVILELGPNRTKVPFEKWAIG"
     CDS             complement(11057..12178)
                     /locus_tag="ctg1_2655"
                     /transl_table=11
                     /translation="MYAVRYELIKTCKQSGARLGRLHTPHGIIETPIFMPVGTQATVKS
                     MTPEELKEIGSQIILSNTYHLYMRPGHELIKRAGGLHKFMNWDKPILTDSGGFQVFSLG
                     PLRKIKEEGVEFRSHLDGSKHFLTPEKAMEIQNALGSDIMMAFDECAPYPSDREYVKNS
                     LERTTRWLKRCKDAHNNTDKQALFGIIQGGMYKDLREQSAKEITNIDLPGYAIGGLSVG
                     EPKPLMYDVLEHTTPLMPKDKPRYLMGVGSPDDLVEGVIRGVDMFDCVLPTRIARNGTA
                     MTSQGKVVVRNATYAEDFTPLDPECDCYACKNYSRAYIRHLIKANEILGARLITTHNLH
                     FLLNLMKQIRQAIMEDRLLDFRNEFFAKYGYEI"
     aSDomain        complement(11063..12163)
                     /aSDomain="TIGR00430"
                     /aSTool="tigrfam"
                     /description="Q_tRNA_tgt: tRNA-guanine transglycosylase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2655_0027"
                     /evalue="4.20E-182"
                     /identifier="TIGR00430"
                     /label="ctg1_2655"
                     /locus_tag="ctg1_2655"
                     /protein_end="372"
                     /protein_start="5"
                     /score="603.0"
                     /tool="antismash"
                     /translation="YELIKTCKQSGARLGRLHTPHGIIETPIFMPVGTQATVKSMTPEE
                     LKEIGSQIILSNTYHLYMRPGHELIKRAGGLHKFMNWDKPILTDSGGFQVFSLGPLRKI
                     KEEGVEFRSHLDGSKHFLTPEKAMEIQNALGSDIMMAFDECAPYPSDREYVKNSLERTT
                     RWLKRCKDAHNNTDKQALFGIIQGGMYKDLREQSAKEITNIDLPGYAIGGLSVGEPKPL
                     MYDVLEHTTPLMPKDKPRYLMGVGSPDDLVEGVIRGVDMFDCVLPTRIARNGTAMTSQG
                     KVVVRNATYAEDFTPLDPECDCYACKNYSRAYIRHLIKANEILGARLITTHNLHFLLNL
                     MKQIRQAIMEDRLLDFRNEFFAKYGYE"
     aSDomain        complement(11066..12163)
                     /aSDomain="TIGR00449"
                     /aSTool="tigrfam"
                     /description="tgt_general: tRNA-guanine family
                     transglycosylase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2655_0028"
                     /evalue="5.40E-174"
                     /identifier="TIGR00449"
                     /label="ctg1_2655"
                     /locus_tag="ctg1_2655"
                     /protein_end="371"
                     /protein_start="5"
                     /score="576.3"
                     /tool="antismash"
                     /translation="YELIKTCKQSGARLGRLHTPHGIIETPIFMPVGTQATVKSMTPEE
                     LKEIGSQIILSNTYHLYMRPGHELIKRAGGLHKFMNWDKPILTDSGGFQVFSLGPLRKI
                     KEEGVEFRSHLDGSKHFLTPEKAMEIQNALGSDIMMAFDECAPYPSDREYVKNSLERTT
                     RWLKRCKDAHNNTDKQALFGIIQGGMYKDLREQSAKEITNIDLPGYAIGGLSVGEPKPL
                     MYDVLEHTTPLMPKDKPRYLMGVGSPDDLVEGVIRGVDMFDCVLPTRIARNGTAMTSQG
                     KVVVRNATYAEDFTPLDPECDCYACKNYSRAYIRHLIKANEILGARLITTHNLHFLLNL
                     MKQIRQAIMEDRLLDFRNEFFAKYGY"
     PFAM_domain     complement(11072..12133)
                     /aSDomain="TGT"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01702.20"
                     /description="Queuine tRNA-ribosyltransferase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2655_0092"
                     /evalue="8.20E-167"
                     /label="ctg1_2655"
                     /locus_tag="ctg1_2655"
                     /protein_end="369"
                     /protein_start="15"
                     /score="554.9"
                     /tool="antismash"
                     /translation="GARLGRLHTPHGIIETPIFMPVGTQATVKSMTPEELKEIGSQIIL
                     SNTYHLYMRPGHELIKRAGGLHKFMNWDKPILTDSGGFQVFSLGPLRKIKEEGVEFRSH
                     LDGSKHFLTPEKAMEIQNALGSDIMMAFDECAPYPSDREYVKNSLERTTRWLKRCKDAH
                     NNTDKQALFGIIQGGMYKDLREQSAKEITNIDLPGYAIGGLSVGEPKPLMYDVLEHTTP
                     LMPKDKPRYLMGVGSPDDLVEGVIRGVDMFDCVLPTRIARNGTAMTSQGKVVVRNATYA
                     EDFTPLDPECDCYACKNYSRAYIRHLIKANEILGARLITTHNLHFLLNLMKQIRQAIME
                     DRLLDFRNEFFAKY"
     CDS             complement(12257..12742)
                     /locus_tag="ctg1_2656"
                     /transl_table=11
                     /translation="MHSLQKQKKNNPILKIAFIFERVLAVVVLIAVFLGTIDVLRLMWG
                     AYIVDFQNPVQYSQLNDFLAQILLLVIGVELVVMLSLHIPGAFIEALLYAIARKMLLLP
                     KNEGMIDVLIGVIAIAGLFAIKKFLVTKDKSALNIMSIHDEEAIKEQQNKEDEDKSI"
     PFAM_domain     complement(12347..12688)
                     /aSDomain="PsiE"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06146.14"
                     /description="Phosphate-starvation-inducible E family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2656_0093"
                     /evalue="3.60E-05"
                     /label="ctg1_2656"
                     /locus_tag="ctg1_2656"
                     /protein_end="132"
                     /protein_start="18"
                     /score="24.1"
                     /tool="antismash"
                     /translation="IFERVLAVVVLIAVFLGTIDVLRLMWGAYIVDFQNPVQYSQLNDF
                     LAQILLLVIGVELVVMLSLHIPGAFIEALLYAIARKMLLLPKNEGMIDVLIGVIAIAGL
                     FAIKKFLVTK"
     CDS             complement(12754..13779)
                     /locus_tag="ctg1_2657"
                     /transl_table=11
                     /translation="LKTSDFKFDLPQELIAQVPIEDRASSRLMVLDKETGNIEHKVFRD
                     IIEYLNPGDCLVLNNTRVIPARLIGEKLETGGKIEFLLLKRTEEDTWQALVKPGKRAKV
                     GTKFSFGNGKLIGEVVDLSDEGSRIIKFHYDGIFEEILDELGNMPLPPYITARLDEKER
                     YQTVYSKHNGSAAAPTAGLHFTEELLNKIKEKGVDIAFVTLHVGLGTFRPVKVEDVLNH
                     KMHSEYYMVSQEAADKINRAKENGKNVICVGTTSCRTIESACNEDGKMKETSGWTEIFI
                     YPGYKFKVLDKLITNFHLPESTLIMLVSAICGKDNVLNAYNEAVKERYRFFSFGDAMII
                     K"
     PFAM_domain     complement(12760..13773)
                     /aSDomain="Queuosine_synth"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02547.17"
                     /description="Queuosine biosynthesis protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2657_0094"
                     /evalue="3.40E-147"
                     /label="ctg1_2657"
                     /locus_tag="ctg1_2657"
                     /protein_end="340"
                     /protein_start="2"
                     /score="489.9"
                     /tool="antismash"
                     /translation="TSDFKFDLPQELIAQVPIEDRASSRLMVLDKETGNIEHKVFRDII
                     EYLNPGDCLVLNNTRVIPARLIGEKLETGGKIEFLLLKRTEEDTWQALVKPGKRAKVGT
                     KFSFGNGKLIGEVVDLSDEGSRIIKFHYDGIFEEILDELGNMPLPPYITARLDEKERYQ
                     TVYSKHNGSAAAPTAGLHFTEELLNKIKEKGVDIAFVTLHVGLGTFRPVKVEDVLNHKM
                     HSEYYMVSQEAADKINRAKENGKNVICVGTTSCRTIESACNEDGKMKETSGWTEIFIYP
                     GYKFKVLDKLITNFHLPESTLIMLVSAICGKDNVLNAYNEAVKERYRFFSFGDAMII"
     aSDomain        complement(12760..13776)
                     /aSDomain="TIGR00113"
                     /aSTool="tigrfam"
                     /description="queA: S-adenosylmethionine:tRNA
                     ribosyltransferase-isomerase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2657_0029"
                     /evalue="2.80E-143"
                     /identifier="TIGR00113"
                     /label="ctg1_2657"
                     /locus_tag="ctg1_2657"
                     /protein_end="340"
                     /protein_start="1"
                     /score="475.0"
                     /tool="antismash"
                     /translation="KTSDFKFDLPQELIAQVPIEDRASSRLMVLDKETGNIEHKVFRDI
                     IEYLNPGDCLVLNNTRVIPARLIGEKLETGGKIEFLLLKRTEEDTWQALVKPGKRAKVG
                     TKFSFGNGKLIGEVVDLSDEGSRIIKFHYDGIFEEILDELGNMPLPPYITARLDEKERY
                     QTVYSKHNGSAAAPTAGLHFTEELLNKIKEKGVDIAFVTLHVGLGTFRPVKVEDVLNHK
                     MHSEYYMVSQEAADKINRAKENGKNVICVGTTSCRTIESACNEDGKMKETSGWTEIFIY
                     PGYKFKVLDKLITNFHLPESTLIMLVSAICGKDNVLNAYNEAVKERYRFFSFGDAMII"
     CDS             complement(14097..15116)
                     /locus_tag="ctg1_2658"
                     /transl_table=11
                     /translation="MQGFEDENRIITSTMKMEDIDIENSLRPKTLEDYLGQEKSKEQLS
                     IFIEAAKSRNEQLDHVLLYGPPGLGKTTLASIIANEMGVNLRITSGPAIERAGDLAAIL
                     TNLNENDVLFIDEIHRINRSVEEVLYPAMEDFCLDIIIGKGPSARSIRLDLPKFTLIGA
                     TTRAGMLTNPLRDRFGVICKLDYYTVDELSKIVLRSSSILDAEIQSNGALELAKRSRGT
                     PRIANRLLKRVRDFAQVRADGKITDKVAKDALELLGVDSLGLDFVDEKLLMTIIEKFRG
                     GPVGLDTLAASIGEDRNTIEDVYEPYLLQLGFINRGPRGRVAMPLAYEHLKIPYPNEK"
     PFAM_domain     complement(14121..14333)
                     /aSDomain="RuvB_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05491.15"
                     /description="RuvB C-terminal winged helix domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2658_0097"
                     /evalue="1.40E-23"
                     /label="ctg1_2658"
                     /locus_tag="ctg1_2658"
                     /protein_end="332"
                     /protein_start="261"
                     /score="82.6"
                     /tool="antismash"
                     /translation="LGLDFVDEKLLMTIIEKFRGGPVGLDTLAASIGEDRNTIEDVYEP
                     YLLQLGFINRGPRGRVAMPLAYEHLK"
     aSDomain        complement(14121..15032)
                     /aSDomain="TIGR00635"
                     /aSTool="tigrfam"
                     /description="ruvB: Holliday junction DNA helicase RuvB"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2658_0030"
                     /evalue="4.60E-148"
                     /identifier="TIGR00635"
                     /label="ctg1_2658"
                     /locus_tag="ctg1_2658"
                     /protein_end="332"
                     /protein_start="28"
                     /score="490.2"
                     /tool="antismash"
                     /translation="KTLEDYLGQEKSKEQLSIFIEAAKSRNEQLDHVLLYGPPGLGKTT
                     LASIIANEMGVNLRITSGPAIERAGDLAAILTNLNENDVLFIDEIHRINRSVEEVLYPA
                     MEDFCLDIIIGKGPSARSIRLDLPKFTLIGATTRAGMLTNPLRDRFGVICKLDYYTVDE
                     LSKIVLRSSSILDAEIQSNGALELAKRSRGTPRIANRLLKRVRDFAQVRADGKITDKVA
                     KDALELLGVDSLGLDFVDEKLLMTIIEKFRGGPVGLDTLAASIGEDRNTIEDVYEPYLL
                     QLGFINRGPRGRVAMPLAYEHLK"
     PFAM_domain     complement(14337..14558)
                     /aSDomain="AAA_lid_4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF17864.3"
                     /description="RuvB AAA lid domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2658_0096"
                     /evalue="1.50E-32"
                     /label="ctg1_2658"
                     /locus_tag="ctg1_2658"
                     /protein_end="260"
                     /protein_start="186"
                     /score="111.2"
                     /tool="antismash"
                     /translation="YTVDELSKIVLRSSSILDAEIQSNGALELAKRSRGTPRIANRLLK
                     RVRDFAQVRADGKITDKVAKDALELLGVD"
     PFAM_domain     complement(14565..15041)
                     /aSDomain="RuvB_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05496.14"
                     /description="Holliday junction DNA helicase RuvB P-loop
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2658_0095"
                     /evalue="7.80E-85"
                     /label="ctg1_2658"
                     /locus_tag="ctg1_2658"
                     /protein_end="184"
                     /protein_start="25"
                     /score="282.5"
                     /tool="antismash"
                     /translation="LRPKTLEDYLGQEKSKEQLSIFIEAAKSRNEQLDHVLLYGPPGLG
                     KTTLASIIANEMGVNLRITSGPAIERAGDLAAILTNLNENDVLFIDEIHRINRSVEEVL
                     YPAMEDFCLDIIIGKGPSARSIRLDLPKFTLIGATTRAGMLTNPLRDRFGVICKL"
     CDS             complement(15223..15825)
                     /locus_tag="ctg1_2659"
                     /transl_table=11
                     /translation="MYSYIKGTVEEIYIDSIVVENNGIGYKINVSSNTIMNLQVGEATK
                     IYTKLIVREDDMSLCGFVSREELKMFELLTSVSKIGPKVALSILSFASPAQLGAYILSE
                     DIGKLSKAPGVGKKTAERIVLELKDKVDKNNIEFEPTLLSQKPTLISQDESVDALVALG
                     YTLSESKEAVQKCKKDGMNTEAIIKKALTYIMSKSLK"
     aSDomain        complement(15241..15822)
                     /aSDomain="TIGR00084"
                     /aSTool="tigrfam"
                     /description="ruvA: Holliday junction DNA helicase RuvA"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2659_0031"
                     /evalue="9.60E-45"
                     /identifier="TIGR00084"
                     /label="ctg1_2659"
                     /locus_tag="ctg1_2659"
                     /protein_end="195"
                     /protein_start="1"
                     /score="150.4"
                     /tool="antismash"
                     /translation="YSYIKGTVEEIYIDSIVVENNGIGYKINVSSNTIMNLQVGEATKI
                     YTKLIVREDDMSLCGFVSREELKMFELLTSVSKIGPKVALSILSFASPAQLGAYILSED
                     IGKLSKAPGVGKKTAERIVLELKDKVDKNNIEFEPTLLSQKPTLISQDESVDALVALGY
                     TLSESKEAVQKCKKDGMNTEAIIKKALTYIM"
     PFAM_domain     complement(15244..15369)
                     /aSDomain="RuvA_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07499.15"
                     /description="RuvA, C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2659_0100"
                     /evalue="1.30E-10"
                     /label="ctg1_2659"
                     /locus_tag="ctg1_2659"
                     /protein_end="194"
                     /protein_start="152"
                     /score="41.7"
                     /tool="antismash"
                     /translation="DESVDALVALGYTLSESKEAVQKCKKDGMNTEAIIKKALTYI"
     PFAM_domain     complement(15439..15615)
                     /aSDomain="HHH_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14520.8"
                     /description="Helix-hairpin-helix domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2659_0099"
                     /evalue="3.40E-17"
                     /label="ctg1_2659"
                     /locus_tag="ctg1_2659"
                     /protein_end="129"
                     /protein_start="70"
                     /score="62.8"
                     /tool="antismash"
                     /translation="FELLTSVSKIGPKVALSILSFASPAQLGAYILSEDIGKLSKAPGV
                     GKKTAERIVLELKD"
     PFAM_domain     complement(15649..15825)
                     /aSDomain="RuvA_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01330.23"
                     /description="RuvA N terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2659_0098"
                     /evalue="1.70E-20"
                     /label="ctg1_2659"
                     /locus_tag="ctg1_2659"
                     /protein_end="59"
                     /protein_start="0"
                     /score="73.0"
                     /tool="antismash"
                     /translation="MYSYIKGTVEEIYIDSIVVENNGIGYKINVSSNTIMNLQVGEATK
                     IYTKLIVREDDMSL"
     CDS             complement(15818..16327)
                     /locus_tag="ctg1_2660"
                     /transl_table=11
                     /translation="MIILGIDPGIAIVGYGIIEYKNSKFKAIDYGAVTTPAHMNISRRL
                     ELVYKGIDTIVKNYNIDEVGMEELFFNKNVKTAITVAQARGVTMLACAHNGKPVYEYTP
                     LQVKQGVVGYGRADKAQVQQMVTSFLSLKKVPKPDDVADALAVAICHAHSNKLEKTLKN
                     IGGKYV"
     aSDomain        complement(15860..16321)
                     /aSDomain="TIGR00228"
                     /aSTool="tigrfam"
                     /description="ruvC: crossover junction
                     endodeoxyribonuclease RuvC"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2660_0032"
                     /evalue="2.40E-45"
                     /identifier="TIGR00228"
                     /label="ctg1_2660"
                     /locus_tag="ctg1_2660"
                     /protein_end="156"
                     /protein_start="2"
                     /score="152.2"
                     /tool="antismash"
                     /translation="ILGIDPGIAIVGYGIIEYKNSKFKAIDYGAVTTPAHMNISRRLEL
                     VYKGIDTIVKNYNIDEVGMEELFFNKNVKTAITVAQARGVTMLACAHNGKPVYEYTPLQ
                     VKQGVVGYGRADKAQVQQMVTSFLSLKKVPKPDDVADALAVAICHAHSNK"
     PFAM_domain     complement(15875..16321)
                     /aSDomain="RuvC"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02075.19"
                     /description="Crossover junction endodeoxyribonuclease
                     RuvC"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2660_0101"
                     /evalue="8.70E-52"
                     /label="ctg1_2660"
                     /locus_tag="ctg1_2660"
                     /protein_end="151"
                     /protein_start="2"
                     /score="175.0"
                     /tool="antismash"
                     /translation="ILGIDPGIAIVGYGIIEYKNSKFKAIDYGAVTTPAHMNISRRLEL
                     VYKGIDTIVKNYNIDEVGMEELFFNKNVKTAITVAQARGVTMLACAHNGKPVYEYTPLQ
                     VKQGVVGYGRADKAQVQQMVTSFLSLKKVPKPDDVADALAVAICH"
     CDS             complement(16639..17268)
                     /locus_tag="ctg1_2661"
                     /transl_table=11
                     /translation="MFEKKKKELFPWKISALILVGVFVLSSGVYIGTRLKHNGVQTGEV
                     VSTSANMNEKSKEAFGLNKNCEVWLQSEGENETNYKRTLTMAGIVPESLLDKTKSEIVS
                     YFKKEYPTKKIKSMDKNEIILVESKYSDNKDVQAMDVTIKGKYTIENDNGNIALYKYDD
                     SGSKTLVEKTKIRVDSLPKTVQDEIKKGVVMDTEEEAYSRLEDFAS"
     CDS             17471..17794
                     /locus_tag="ctg1_2662"
                     /transl_table=11
                     /translation="LERINCNVINCSHNNSHICYADKIFINGEKAHNDRHTCCSSFLDE
                     SIYSNLSSNVNNKNCEELVCTVKNCKYNKDGSLCTLDNILVAPETDRVNLYIETCCSSF
                     ECK"
     PFAM_domain     17480..17596
                     /aSDomain="DUF1540"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07561.13"
                     /description="Domain of Unknown Function (DUF1540)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2662_0102"
                     /evalue="4.60E-08"
                     /label="ctg1_2662"
                     /locus_tag="ctg1_2662"
                     /protein_end="42"
                     /protein_start="3"
                     /score="33.4"
                     /tool="antismash"
                     /translation="INCNVINCSHNNSHICYADKIFINGEKAHNDRHTCCSSF"
     PFAM_domain     17663..17782
                     /aSDomain="DUF1540"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07561.13"
                     /description="Domain of Unknown Function (DUF1540)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2662_0103"
                     /evalue="5.50E-12"
                     /label="ctg1_2662"
                     /locus_tag="ctg1_2662"
                     /protein_end="104"
                     /protein_start="64"
                     /score="45.9"
                     /tool="antismash"
                     /translation="CTVKNCKYNKDGSLCTLDNILVAPETDRVNLYIETCCSSF"
     CDS             18062..18916
                     /locus_tag="ctg1_2663"
                     /transl_table=11
                     /translation="MSTFYIQFLYFVIYSFIGWCCETTYCSVLQKQFVNRGFLNGPFCP
                     IYGFGALAIVATLTPFVHNIPLLFLFSIIITSIMEYCTSFILEKIFNMTWWDYSKHKFN
                     IHGRVCLENSLMFGVLSLIVMLIVHPIVVDFINSISKNVLFIFAISIEIYFVLDLVITV
                     HTILQLNGKLKQINLIIKELKDKKEYYKLITQETIENKLESLVENRLDTLEDRFEILKE
                     KENYRYAKNRIDELKNKLNTLLSNHKLLHRRIIKAFPNISSNKHTDILNKIKENIKSIK
                     KDK"
     PFAM_domain     18086..18550
                     /aSDomain="ABC_trans_CmpB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06541.13"
                     /description="Putative ABC-transporter type IV"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2663_0104"
                     /evalue="1.60E-53"
                     /label="ctg1_2663"
                     /locus_tag="ctg1_2663"
                     /protein_end="163"
                     /protein_start="8"
                     /score="181.0"
                     /tool="antismash"
                     /translation="LYFVIYSFIGWCCETTYCSVLQKQFVNRGFLNGPFCPIYGFGALA
                     IVATLTPFVHNIPLLFLFSIIITSIMEYCTSFILEKIFNMTWWDYSKHKFNIHGRVCLE
                     NSLMFGVLSLIVMLIVHPIVVDFINSISKNVLFIFAISIEIYFVLDLVITV"
ORIGIN
        1 actaaatctt gtccatattc aaaagttcct tgacttacat cttcccagtt ctttttatca
       61 ttacttactt gtattttgta attagttaaa ggattgtatg ttgtgctagt attctttcta
      121 aagttaaata atccttttaa tgagaacttc ctagcttctg tctctggttt tgtatatttt
      181 agtcctacta taggtaatgt ttctttcatg tctactatta tatatggatt ttcctctaca
      241 tttatatcag ggtctttttg agggtctttg ttccactctg ctttacttat tatctttcct
      301 ttatatgtag tatttgcatc attatctttt atattatcaa tttcaggatt ttgtaatggt
      361 ccatgtgagt cattttcagt tctaacatca ccgtcagaaa cagtatttgt tatgaatgac
      421 catgctgatt tatttatttt cccttcatct gataatttta cagtaccaac ttcaaattct
      481 tctgttggat ttaggtgata atcatatgca actaccttat atgtaaatgc tctgttatta
      541 agaggagata tattatcagt aaatttagtc ttactatttc cttttgcatc cacaaatcca
      601 actgttctgt attttacctg tgttccattt tcaccatcta aataatttcc atcacttctt
      661 attatttcgt atcctagtat cttatcttta tccttatcta catctaggtc tatagatatt
      721 ttattagatt taactagaga accactttgt attccatcag aaaaactagc acttacttta
      781 gtatcttttg ccatactagc tatattttca tttaaaatct ttcttctagc ttcgtcattt
      841 acatattgta tctttcttga ttctttttcg tagttcttac tatccattat actgtttaat
      901 tctggtgtaa tttctactcc ccatgcctta aagtaatctc ttaaatcttt ttcaacaaca
      961 cttgatgcca ttgctactag catttggtct tttggcaaac tattaattgg gtcactactt
     1021 gaaagtgctc tgtattttct tgaaatcttt gcatagaatg tatcattact taaatcagca
     1081 tctgagttat tctttaacat tgaacccgta aaatcatcat cataagctag atgtaattgc
     1141 cataacattc caagcctttc aaatacattg cttggtatac ctaagctatt tgaagttaca
     1201 tgctcatata tcttatccat tgttgaacct tcaattcttg aatgtgtctt atcatcaaag
     1261 gtctgagcaa gtaaagcaag tacattgtta ctagtttcgc tatatgtcat ctttccaata
     1321 tctgtaacat gtcctatctc atgacctatt ccccatccaa ataagtttcc tcctgtagct
     1381 tttccactat catctatttg gaaaggtact ccattcataa gccctggaac tgaaccatat
     1441 tctactccta catgtaatcc agaagcatac ataaatgctc caataaacat tctttggtat
     1501 tttatgttca tacgagattt tggagccata tcatttttag ttaagttaaa ttcattatca
     1561 tctacagttc cattaccatc taaatcttgt gttttaaata ctcctctttc tgagtaaact
     1621 aaatccatta tttgttccca tgcaagcata ctattatata atctatctac ttgtgtattt
     1681 aaatcagcat ttccttttga tatcccttga tatacagctg ttgcaggaac atttaatgtt
     1741 actttatcac tttcaatatc tgtagtgttt aacacaccag ttttttctga atatccatat
     1801 gaattaccaa catttgttcc tggataatat ggttctcctt ttacagcatc tttatatcta
     1861 gctaattctt ctatatatgc ttttatcttt ttcttagatt cagaaactcc cgcaggactc
     1921 ttatcattta ttgttccatt tagattaagg tgtggtatct tagtagctcc tgctacacgt
     1981 acttttatat ctcctccact tggagtatct tcagcgtatc ttatgtataa acttcctcca
     2041 cattctatat ctaaactatg aagtttgctt aattgaatta cattttttcc agtgttaaga
     2101 tttatttctc cactcttata tgcaccagat tctccatagt actgtgtata tatcaactta
     2161 ggagtttttc cacttttact tccaacatat actgtgattt catctcctgc tctagcagct
     2221 actcctaatg cctgccagtc attttgcata cctaaattat tggaatttac agtatactgt
     2281 ccgtttttat ctttatattt tcctaattta tttatttctt gatttacagt agttacatca
     2341 gtaagtgtgg ctctatcatt atataagtct tgagctaatt ttaattctct ctcaataact
     2401 gtcttatatg gatgatattc tccactagct ttatctggag tatttaatct atcttttaat
     2461 tcagttattt tttcttgagt tacatcttct tttaattcaa cttgtaggtc atccataaat
     2521 agatttctta catcatcttc tatactgtca tactcataaa acttaagttc tgatatatta
     2581 gacttatatg aataggatga acaaacactt acttgtatct tggtagcagt tattggttct
     2641 tttaatctaa ccattacata cttattatta tttacagggt ctgtctttgt ttcaaaagga
     2701 acatccccca gattgtgtaa ttgaccattt tcatcccaat atcgtacctc aaagtcattt
     2761 attgtcttat cagaaacatc aaaacgaggt gtagccataa aagtatccat agtataagat
     2821 ttatcaaaag ttattattgg tcctctattc gttccctcag ctgcattata tgttgggaat
     2881 gtccaatgtg ttgtaaagtc cccatctact acattgaatt tatcaaatgg atttttatca
     2941 ctatattcac ttttgtcata tcctgctgga taagtaacat ctacaatgtg atttgttggt
     3001 attccaaatc caccattctc tttaggagta ttaattaatc tatagttagg tgttgttggt
     3061 gcatccatgc tttcagttgt acctatatat gttttagaca ttccactagt tcccaagtgg
     3121 ttagtagctg tcattctaac ttcatatgtt gtattatcct taagaccttc tatctttgaa
     3181 cttgtcccac gaataagctt atcattgtat tttatccaag acccattaga gcctttttct
     3241 ttatagtaca agtcaaaatc tttagcttgt ttatgatttt tccagcttac atcaagagat
     3301 ttaaatttac ctttaacatt tataccttct ggtggttctg gttttgtgtc tggaacaact
     3361 tgaaattcta atatactatc tgggctaaat tgtataggtt tatagtttga atctacattt
     3421 tctggtactc cgtctaagtt ttctggtgtt gcatctttat aaccactaga ccaatctcca
     3481 tttaaagatt gtatgctaac cctatatagt ccatatgctt ctatatctct aacttctatt
     3541 gtatttttac tggtttgtaa ttttttagta gataatactt ttcccttact atcaatttta
     3601 tctagtataa gttcgtatgc tgatacattt acttcattat tccaataaaa agatactttt
     3661 tcatttccaa cagcagtgct agtcgatatt ttatttattt taggtatatt catctctggc
     3721 tttggtattt ctttatatac attgtttaaa aattcaactt ttgatatttc tgcaagattt
     3781 ctatcgtttg ctgttgtagc tgttattttt atagttatct tttttactgc tacttgttta
     3841 ccaagattta ttactatatc actattttga acatctgcat atgtttctaa tgttgactta
     3901 ctatatgtag atgttgtaga gttatcatct ttactgatat taccctcttc ttttggagta
     3961 tcttcatctg aattaggttt atccattgat gaattttctt tatcattatt tttatcttga
     4021 ttggtattag agtttacttc ttgtttatcg ctattttcct gttgttcatc attattttca
     4081 tctttattat ttgagttatt atcagtctgg tttatatttt catctttatt atttacttct
     4141 tcttgattta cttcttcttg ttcgttattt acttcctctt gttgctcctc atcttttaag
     4201 tttttcatat attctttgtt ttcataagga atctgttgaa cattaccatc tttgtcagta
     4261 acctcaacta ttccttttgc tggagcagta ccttctggag cttttatatt gatgacttcc
     4321 atattaagtg cttctgataa agctatatcc attactgctg gtttttcctc agatatttca
     4381 tcattttttg aagatattgt aactccatta ttttctccac taaataaatt ttctacatta
     4441 ccattaatat ctacatcact atttcctttt aattcaacct tacttgtatc tactatagga
     4501 ttggtagata ctatactttc taggcttttt gcatcttcac tttgtcctaa atttttctgt
     4561 acataatcta agtcaacaat atctaccttt ccatctctat ttaaatcaaa ttctctttta
     4621 tttgaatcta tattctctaa aaccttatta taatcactct tatctacttt accgtctcca
     4681 tttacatcac ccattaagaa caattcataa tttaaaggtt tatttttatt atctacactt
     4741 gctctattgc ttaataagac tctttgtgaa taacttgata tatcaatgtc tttaatttct
     4801 ttgttcttaa atccatctcc agagacttct acattgtatt ttccaacagg taaattatta
     4861 aatacaatat tataatatga tatattctca tctttatttt ttatttcact tctacttgca
     4921 gataattttt ttatagtata ttctatatta tctgtcccaa catttactgt tcctgaatct
     4981 ttttctccaa gctttattat tccactattg ttactatcat cttttaatcg taactgcata
     5041 ttagtcatac tttctgaatc gctatttttt attggcagtg aaaaatttaa atctacttca
     5101 agactccccc ttaacttttc tgtaactgat ttttcaactg cccttagctt cccctctaat
     5161 ataggttctg caaaaacgtt tagtggtgca ctacacatag atactgctag tacacaagat
     5221 attgcctttt tcatgaaata acaatcctcc cttaataaat atctaatttt tcatgaattt
     5281 aaatactata agtttcagac aataaaaaaa gacactcaaa gagaatctta attataaaat
     5341 aaaaagactt tactcttttt agcaactggc tgatatggct ttaaaagctt taatccctat
     5401 agttttgcgt cattagattt ccctaatttt gccatttaat tttcactact ttcttaccca
     5461 ttttatacta tatttaaact ttttaataca atttttttag attaaattat aaaaaaataa
     5521 catttatatt aatttattaa tataaatgtt attttccatt ataatttaat tatttatata
     5581 gcttccttac aagcataatt ttgtgtatat tttcttattc tttatatctt ccataaaatt
     5641 catgtgtagc atatagattc ttatctcctg ttatagctat accaaatccc attatttcat
     5701 accctttatg caacatgtta gttccttctt ctggatttgt cttccactca ttaaaaataa
     5761 agtttcctat atcatctgca tctctatttg tatatacagg tttatctgga attttatatt
     5821 taattatatt ttcaccttga actgctatat atccaggttt aatctcactc caatctaagt
     5881 atttcaaaaa agtagaatat gaattttttc catttatcgt atgagataaa gtcttcttat
     5941 ttgccattaa attagaccaa tcatttgcta aaccctctaa tctgcttgct acagataacg
     6001 ctcttactcc attctctttt ctatactgct ttgtaagagc atatacttta ccctttattc
     6061 tctctttaaa tgctctatca tttggattgt aatataaacc ttgttgattt ggtgaagctt
     6121 gatttataca ttgcttgata acattctgat ttatgcctcc tagtacagtc aatttgtctg
     6181 caccacttaa aatactcttg ttactgccat tttcaactaa aactacagga gcattttttg
     6241 ctattgtaga ggcagccaaa gcgtctgtta attgtaagcc tttacttaga taaaattctt
     6301 tactattttt ataaaactct tgtataacta tcttattagt ttcaaatcta tctgtgccac
     6361 ccaatctaat agaatttgtg ctcttaacta attcgtcgct gattatttca ctagaaccaa
     6421 gcgcataact ctttaagcct gtcgtgtcaa atcccacact atttccatct gtaagtatta
     6481 taggtactcc atctctagca gctactggtg atgcacttat cgcatctgct tctcctgtaa
     6541 atccattggc tataattact ttatctattg gcttaatttc tttgattttt tcagctattt
     6601 ttatacttgt atcaaatcta ttttcaccaa agattctttg tacaaccttc tttttggata
     6661 gtaactgatt ctcaacattt ttacttattg ttgattctga gcctattata tacacagtct
     6721 ttgctttgtt taatctttcc atagttgtgt ttggaatctg attttgtttt gtcatcaaaa
     6781 taggcgcatt taaggctcca gctaaaccac ttgcacttag accatctgct aagctattat
     6841 ctgagttgat tagtattgct gtattgtagt tttgcttatc tgctattttt gctgctgtct
     6901 catatctgtc attccctttt atttgctcaa ctgatgtcaa cgcatttacc ataggagtat
     6961 ttaccattac taaaaatagt gtaagtccta tagctaatat ctttttacta ttcttcatat
     7021 tattttctac ccccaatgta cttttcatat tttttattag tactcatact tatttttaat
     7081 caaaagttac aattttgtta ccatatttta tatatgatac catagttatc catacaactc
     7141 aaacaatata cctaaagttt ttattctcta taaattcaaa acattataat ttattttatt
     7201 taattaagtt ataagttcaa aataatttat gttaataaga tgtttaatca ttataagaag
     7261 tatcttttta taataatttt tgcaatatga atttctcaac attataatca aaaaataaaa
     7321 taaggtatct caatctaatt ctaaatgaga caccttattt ttattatttt atcttgttat
     7381 ttgtatattt tataatatct acactatgtc ttacatatta acgcattgta taatcatata
     7441 ttatctaaac aaacttttaa tattaattcc tatatcttat tagttcttag taaataagtt
     7501 tattttttct gctatttttt caatagcgtt tttagctatt ccttcaccta tttgtactaa
     7561 cttagtagca ttcttaagtc ttaactcaac tacttcttct tgtgatttag aaagttcttc
     7621 tgtagttaat actattggag cctttgaact agctgcaagt ggtgctgctg taagtgcatc
     7681 aactaattgt ccatttccac ctacataacc atcttttgct acatatgctt tagttgcacc
     7741 tgcatagtat ttattgatta ctttagcatt agtatctttt ctattttctc cagctaatct
     7801 ttcaacttta ttatttaaat ctatatcaac taatttgtct tcaacttctt ttgatacaga
     7861 attttctcca cccactattt ctaattcttt tccttttaat aatttttcag catttgcatc
     7921 taattcgtta cctgtaacta ttattggagc accaaattga gcagctctag ctgatatact
     7981 catagcatca gcttctccat ttccacctac tacaaaagca gtcttaaatg tatcttttaa
     8041 ttgttttgct atttctaaag aagtttcaaa tctatcttct ccagaaactc tctcaacttt
     8101 acttacacct aatttagaaa gtttttcttc agtttctttt gatactttag attctccacc
     8161 tactatatat attttcttag aagatagatt acttccaagt actcttaata tttcagcttc
     8221 tatttctgat ggtagtgaat cttttttaga taataatatt ggtgcatttt tttgagaggc
     8281 aagtggtgct gatgctaatc catcaactat agcatcttct ccaactaaaa ttatagcttc
     8341 tgcttctcca tctttgaatc tctctttact aacttctact gctgttgtaa atcttgaatc
     8401 accagataaa acttctactt ttaattcttt tccacctttt acatcagtta atactttgtg
     8461 taagtctcta actaacttat ggtttttact tgaaacactt attgtttctg gcttttcatt
     8521 tgccttgctt aaaactatat caaagcttga tttttctggt ttatctttat catcactatc
     8581 ttcttgttct tgagtaagga ttgcttcatt ttcaaatgtt aaagcatatc catttttaac
     8641 tttattaact atttctcttc ctaatgtagt taatctaatt ccatcaaata attcttctgc
     8701 tgatatgtct tgtaaatctg cgtttttaac tgttatcgta tgtaattctt ttgaatctat
     8761 gtcactataa ctcttttcat aaccttcaaa agtaccttct tctgatgtta tcacttttga
     8821 gaaatctaaa tgttggtctc ctacatttaa tgtaataaca tttgctgaat cttttgctct
     8881 ttttacttca actgtatttg tagattttat agttgctgtt aacttgttat cagaatcttc
     8941 tgctaaagtt gcattgtaag cattaactgc atctactatt tcttgagcag ttttgtagtt
     9001 ttcaatttta tagtcaacta cttttccacc taacacttga tgtcctttat cttgaatagt
     9061 aacttttaaa ctttgccctt ctgttaaaga gtttatctta ttttgtaatt gagttgcatt
     9121 agttaagttt acattgtcta cttttatatc gtaaactcta tcatttacat ttgctcctgc
     9181 ttttgtatct tcaaacttaa cttctaatgc ttttctaacc tcttcgatta gtttagcaga
     9241 atctttcgca cttactgtgt aatttttatc aacattttct gtcacagtat tgtctgcgaa
     9301 tattggtgct gctgcactca taactgtagc acctgccatt actattgcca tacttctctt
     9361 tttgttgctt aacatattta tgtcctccga atattatttt ttatttttta tattcgtatt
     9421 tcccacacat aaataatatt atatataata ttatttttca atatatttta tgtgtttaca
     9481 taatttacta acacaaacac taataatatc ttcttgaacc ccttccccct gcttagctct
     9541 ctataattat gctcaaagat agaaatccta ttttatagtg attttctact aaacaatcat
     9601 atactaacaa aagtattcaa actccatttt tatatactac tatgcactaa tttttgcttt
     9661 actcttatta cttaaatata tatcactaaa ttaatatcta tctccatata ttaaaatata
     9721 taacatatta taaaaatcat cataaattag agtttaaaat taaaaattat tctaatacat
     9781 gtaattgata aaaaataaaa tataagagta gctactttaa aataaatgct cttatatgat
     9841 tagatatttt tgcataatta aacgataaga aatcaaattt aattttacat aaatagaata
     9901 tatattttta tataataatt gaaaataaaa gaggatacct cataatgata aaagaatcac
     9961 tttgagatac cctcttacaa acaactaaat caataatttt ctatctttca cactcttgat
    10021 ttgcaactgt acaagaagtt ttacaagctg attgacaaga agtttgacac tctccacatc
    10081 caccttttgc agcactttgc tttaaagtag cttgagataa agtttttaca tgtttatttt
    10141 ccattttcaa cgcctccatt tctaattgtt tcctattgat tatatcataa aactacttta
    10201 atataaactc tatttaaagt tgacacccaa tacgcctcca atgcctcctg ctgctgatat
    10261 taacaataac ttataaatca tccctacttc aaatacaaac ttttcttgtg ctaaaaacac
    10321 agtcaaaaaa atacatacta tgtacaaaag tcctactaaa agcccataca taagtccttt
    10381 ttctttcatg tgttttgaag tgtaaaaccc tcctatagct gcagaaatag tagttataaa
    10441 tgatgagacc atagttatat tatctccacc aatatctgta aatgtcaaaa ataagttata
    10501 cactaataaa acagccaaag ttattatata tgcatatcct agacctttaa aaatataatt
    10561 agattttccc ataaaaaaac ctcctctcaa attaatatat attcgagaaa aggcttttaa
    10621 attactaatt tagtcttctt ctatttcttc ttttttagat ttaacagttc ctatagccca
    10681 tttttcaaat ggaactttag ttctatttgg tcctaattct aatattacaa catcatcttc
    10741 aactttagct acattagcta ctattccacc tattgtaatg accttgtctc ctacacttag
    10801 gctacttctc atttctttta attgtttgtc ttttttcttt tgaggtctaa tcattaggaa
    10861 ataaaagatt gcgattacta ctacccatag acctatactc ataattattt gttgctgtgg
    10921 cattaatttt tcactccttt gtaaattata ctcttttgta aatcataata aatgtttata
    10981 taacaattta ctttctctat ctttgagtac tattgaatat tatatattaa aatgattata
    11041 attaatagtg caaaacctat atttcatatc catattttgc aaaaaattca tttctaaaat
    11101 caagtaatct atcttccatt atcgcttgtc ttatttgttt cattaaattt aataaaaagt
    11161 gaagattatg agtagttatt aatcttgcac ccagtatttc atttgctttt ataaggtgtc
    11221 ttatataagc tcttgaatag tttttacaag cataacaatc acattcaggg tcaagtggag
    11281 taaagtcttc agcataagtt gcatttctaa ctactacttt accttggcta gtcattgcag
    11341 ttccatttct agcgatacga gtaggtagga cacaatcaaa catgtctact cctcttataa
    11401 caccttctac taagtcatct ggactaccaa ctcccattag gtatcttggt ttatcctttg
    11461 gcataagtgg agttgtatgc tctaacacgt catacataag tggttttggt tctccaacac
    11521 taagtccacc aatagcatat cctggtaaat caatattagt tatttctttc gctgattgtt
    11581 cccttaagtc tttatacatc ccaccttgta ttataccaaa taaagcttgc ttgtcggtat
    11641 tattatgggc atctttacat ctttttaacc atcttgttgt tctttctaaa gaatttttta
    11701 catattctct atctgatggg tatggtgcac actcatcaaa tgccatcatt atgtctgaac
    11761 ccaatgcatt ttgtatttcc atagcttttt ctggagttag aaaatgtttt gaaccatcta
    11821 agtgtgacct aaattctaca ccttcttctt ttatctttct taaaggccct agactaaata
    11881 cctggaaccc tccactatct gtaagtattg gtttatccca attcataaac ttatgaagac
    11941 caccagctct ttttataagt tcatgacctg gtctcatata taaatggtat gtgttactaa
    12001 gtattatttg tgaaccaatc tcttttaatt cttctggtgt catagatttt acagttgctt
    12061 gagttccaac tggcatgaat attggtgttt caataatccc atgtggagtg tgtaatcttc
    12121 ctaaccttgc accactctgc ttacaagtct ttatcaattc gtatcttact gcgtacataa
    12181 agttctcctt aatcatattt atttctcatt atttcttaag atatatttgt aataagctat
    12241 tcatataatt tattgtctaa atagatttat cttcgtcttc tttgttctgt tgttccttaa
    12301 ttgcttcttc atcatgaata ctcattatat taagagcact cttgtctttt gttactaaaa
    12361 acttttttat agcaaatagt cctgctatag ctataactcc tattaaaaca tctatcatac
    12421 cttcattttt aggcagtagc aacatttttc tagcaattgc gtaaagtaat gcctcaataa
    12481 atgctcctgg tatatgaaga gatagcatta ctacaagttc aacacctatt actaaaagta
    12541 atatttgtgc taaaaaatca ttaagctgac tgtattgtac tggattttga aaatcaacta
    12601 tatatgctcc ccacataagt cttagaacat ctatagttcc taaaaatact gctattagaa
    12661 ctactactgc taaaacacgt tcaaatataa aagcaatctt taatataggg ttattctttt
    12721 tttgtttttg taaactatgc atctattacc tccctacttt ataatcatag catctccaaa
    12781 actgaagaat ctatatcttt cttttactgc ctcattatat gcatttaaaa cattatcctt
    12841 tccacaaata gcacttacta acattattag tgtagactct ggtaagtgaa aattagtaat
    12901 aagtttatct aaaactttaa atttataacc tggatatata aatatttctg tccatccact
    12961 agtttctttc atctttccat cctcattaca agctgattct atagttctac aactagtagt
    13021 accaacacat attacatttt ttccattttc ctttgctcta tttattttgt cagctgcttc
    13081 ttggctaacc atataatatt ctgaatgcat cttgtgattt aaaacatcct ctacttttac
    13141 tggtctaaaa gttcctaagc caacatgtag agttacaaag gctatatcta cacctttttc
    13201 ttttatttta tttaacaatt cttctgtaaa atgtaatcct gctgtaggtg ctgctgctga
    13261 accattatgc tttgaataaa cagtctggta tctttctttt tcatctagtc tagcagtgat
    13321 atatggaggt agtggcatat ttccaagttc atccaatatt tcttcaaaaa ttccatcata
    13381 atggaatttt ataattcttg aaccttcatc tgataaatct acaacttctc caattagctt
    13441 tccatttcca aaagaaaatt tagtccctac ttttgctctt tttcctggtt ttactaaagc
    13501 ctgccaagta tcttcctctg ttctttttaa taataaaaac tctattttac ctccagtttc
    13561 aagcttctct cctattaatc tagctggtat aactctagta ttatttaata ctaagcaatc
    13621 tcctggattt aaatattcta ttatatctct aaatacttta tgttcaatat tacctgtctc
    13681 tttatctaat accatcaatc ttgagctagc tctatcttct ataggaactt gagctataag
    13741 ttcctgtggt aagtcaaatt taaaatcact tgttttcaat gttaaacttc ctctcttaaa
    13801 atttctccag ctacaataat atcaaaaaaa caacttattt tccacaatat taccataatc
    13861 tatcaagaaa ttgctatttt taacagacac catatccaca atatatagat atttttccac
    13921 gatatacatg ccttatccac aatatataga tacaatacac acaattttta tcgtgtttat
    13981 ccacagtatc tacagatata attaccattt tgtggatatg tttgaatttt tagccatttt
    14041 agaaatattt taatttaatg actcttttat tttataaata ctcgtataat ctatttttat
    14101 ttttcattgg gatatggaat ttttaagtgt tcatatgcta atggcatagc tactcttcct
    14161 ctaggacctc tatttataaa tcctaattga agcaaatatg gctcatatac atcttctatt
    14221 gtatttctat cttctccgat agaagctgcc aatgtatcta aacccactgg tcctcctcta
    14281 aatttttcta ttatagtcat aagaagcttc tcatctacaa aatcgagacc caaactatcg
    14341 actcctaaaa gttccagagc atcttttgcc actttatcag ttatttttcc atcagctctg
    14401 acttgtgcaa aatctctaac tctttttagt aatctatttg ctatccttgg agtccctctt
    14461 gaacgttttg caagttctaa tgctccatta gactgtatct ctgcatctaa gatgcttgaa
    14521 gacctaagta ctatttttga aagttcatca actgtataat agtccaattt acaaataaca
    14581 ccaaatctat ctctaagtgg atttgtaagc ataccagctc ttgtagtagc tccaataagt
    14641 gtaaatttag gaaggtcaag tcttatgctt ctagcagatg gccctttccc tattattata
    14701 tctaggcaaa aatcctccat tgctggatat aaaacttctt caacacttct attgattcta
    14761 tgaatctcat ctataaataa aacatcattt tcatttaaat tcgtaagtat ggctgccaaa
    14821 tctccagctc tttctattgc aggtcctgac gtaattctta aatttacccc catctcattg
    14881 gctattatac ttgctagtgt agtttttcca agacctggtg gtccatataa aagcacatgg
    14941 tctaactgct catttctcga tttagctgct tctataaata tactaagttg ttctttggat
    15001 ttttcttgac ccaaataatc ttctaaagtt tttggtctta aactgttttc tatatctata
    15061 tcttccatct tcattgtaga agttattatc ctattttcat cttcaaaacc ttgcatttat
    15121 acccctcctc tcgtactttt gaaaatctac tttatatatt ttcaaattta cataaactcc
    15181 ttaaatattg ttttaaaatc caaatattat aaaatccaaa tactatttca aggatttact
    15241 cattatatat gtaagtgctt tctttataat agcttctgta ttcataccat cttttttaca
    15301 tttttgaact gcctcttttg attccgacaa agtatagcct aaagctacaa gtgcatctac
    15361 agactcatct tgtgatatca aggtaggttt ttgtgataat aacgttggtt caaactctat
    15421 gttatttttg tctaccttat ccttaagctc taagacgatt ctttctgctg tctttttacc
    15481 aacaccagga gctttggata attttccaat gtcttcactt aaaatatatg ctcctaactg
    15541 tgctggtgat gcaaatgata gtattgaaag cgccacctta ggtcctattt tagatacaga
    15601 tgttagtaat tcaaacatct taagttcttc cctacttaca aaaccacaaa gactcatatc
    15661 atcttctctt acaattaatt tagtatatat ttttgtggct tctcccactt gtaaattcat
    15721 tattgtattg gatgatacat ttattttata tcctatccca ttattttcaa caactatact
    15781 gtctatataa atttcttcta ctgtaccttt tatataacta tacatactta ccacctatat
    15841 tctttagagt tttttcaagt ttgtttgaat gagcatggca aatagccaca gctaaagcat
    15901 ctgcaacatc atctggtttt ggaacttttt ttagacttaa aaatgaagtt accatctgtt
    15961 gaacttgtgc cttatctgct ctcccatatc caactacacc ttgttttact tgaagtggag
    16021 tgtattcata tacaggcttc ccattatgag cacatgcaag catagtaaca cctctagctt
    16081 gtgcaactgt tatagctgtt tttacattct tgttaaagaa taattcttcc attccaactt
    16141 catctatatt gtaattcttt actattgtat caattccttt atacacaagt tccaatcttc
    16201 tcgatatatt catatgggca ggtgttgtaa ctgctccata atcgattgct ttaaacttgc
    16261 tatttttgta ttcaattata ccatatccaa ctatggctat acctgggtca atccccaata
    16321 ttatcatttt ttaaaattcc ccctaaaaat aaaagaaata ccaaaatgta tttctcataa
    16381 aaacttatgt tctaaatcat tatatcataa ataatattaa caaatcataa aatgctctat
    16441 gtaaaatata aaatcaaata aaaaagttat atcaaagcaa gattttacct caatataact
    16501 tttatattta ttacaaataa attattgtat ttttatagga attaaatgtg actacaattt
    16561 taatactaat ctatttaata ttaaattatt tattattaat ttacttagta tttaacttaa
    16621 aataatatta atttactatt aacttgcaaa gtcttctaat cttgaatagg cctcttcttc
    16681 agtatccata actacacctt ttttgatttc atcttgaact gttttaggaa gtgaatctac
    16741 tcttattttt gttttttcta ctaatgtttt acttccgcta tcatcatatt tatatagtgc
    16801 tatatttcca ttatcatttt caatagtata tttacctttt atagtaacat ccattgcttg
    16861 tacatcttta ttatcactat atttagattc taccaatatg atttcatttt tatccatact
    16921 ctttattttt ttagttggat attctttttt aaaatatgat actatttctg acttcgtctt
    16981 atctaataat gactctggaa ctattcctgc cattgtaagt gttctcttat agttagtttc
    17041 attttcgcct tcactttgaa gccaaacttc acaattttta tttaatccaa aagcttcttt
    17101 tgacttttca ttcatattcg cactagtact tacaacttca ccagtttgaa ctccattgtg
    17161 ttttaatctt gtccctatat aaactccgct acttaataca aatactccaa ccagtattaa
    17221 ggcagatatt ttccaaggaa ataattcttt tttcttcttt tcaaacattg attacgcctc
    17281 ctttttctat tattttctcc aagctgtaag tttttataca atttaggtaa attttagaag
    17341 aaaatatatt tatatttcaa attactctaa gaatagatat tttctaaaag gtagttttct
    17401 cttaatggtt atattcttgt aattatatgg acataattta taataaataa tcgtttagga
    17461 ggtaataact ttggaaagaa taaactgtaa tgtaattaac tgttcacata acaacagcca
    17521 tatatgttat gcagataaaa tttttataaa tggtgaaaaa gctcacaatg acagacatac
    17581 ttgttgtagt tcatttttag atgaatctat ttatagtaat ttatctagca acgttaataa
    17641 taaaaattgt gaggaattag tttgtactgt aaaaaattgt aaatacaaca aagatggtag
    17701 cttatgtaca cttgataata tattggttgc tcctgaaact gatagagtaa acctttatat
    17761 tgaaacatgt tgctctagtt tcgaatgtaa atagtcatag tataaatata agggtgtcaa
    17821 atgtaattaa actaacatag tgtagagtat ctacaactat tagtttgatt atacttgaca
    17881 cccttattta ttttaaataa aatttcatta ttataaccat gtttataatg ttctaactgt
    17941 aattaaattt gataaatttc tataaattgg tataatcaat atgtaaattg aatttagtaa
    18001 attaatcata aaaataaaat atcgagtata tagtgttata ctaactagaa atgaggtgct
    18061 tatgagtaca ttttatattc aatttcttta ttttgtaatt tatagcttta taggatggtg
    18121 ttgtgaaact acatattgtt cagttttaca aaaacaattt gtaaatagag gttttttaaa
    18181 tggtccattt tgccctatat atggatttgg agcattagca atagttgcta ccttgactcc
    18241 ttttgtacac aatattcctt tgttattttt gtttagtata attataacta gcataatgga
    18301 gtactgtacg agctttattt tagaaaaaat atttaatatg acttggtggg attattctaa
    18361 acataaattt aatattcatg gaagagtttg tctggaaaac tcacttatgt ttggtgtatt
    18421 atcattgatt gtaatgctta tagtacatcc tattgtggtt gactttatta actctatctc
    18481 taaaaatgtg ctatttatat ttgctatatc tatagaaatt tattttgttt tagatttagt
    18541 tatcacagtc catacaattt tacaattaaa tggtaagtta aaacaaatca atcttataat
    18601 taaggaatta aaagataaga aagaatacta caaacttatt acacaagaaa ctatagaaaa
    18661 caaacttgaa tctttagttg aaaatagact ggatactttg gaagataggt ttgaaatact
    18721 taaagaaaaa gaaaattatc gctatgctaa aaatcgtatt gatgagctaa aaaataaact
    18781 taatactttg ctgtctaacc acaaattact tcatagacgt ataatcaaag cattccccaa
    18841 cataagctct aataagcata cagatatttt aaataaaatc aaagaaaata ttaaatcaat
    18901 taaaaaagat aaataataaa ataaacacat aagttaaata ataaaaatac taatacataa
    18961 gattaaggtt tagaatattt tttgtaaaat actctaaacc ctaattaata tactattatt
    19021 tttaatctta atttataatt ttagtttatt ttaattttaa ctcagtaaat ttaagcgttt
    19081 aaacttcaat acactaatat actaccccat caatatctca actgattctc taagtgtgct
    19141 aatctctccc acatttccag ggaaaattat atatggcata ttaggaaatt tgctttcttt
    19201 gcctgtcatc catactggta taccaggttt tatctgtccc attactgtag ctttttttac
    19261 tcttagtgct ttagtaccaa catcactaga agtaattcca cccttagcta taataaaatt
    19321 tggtcttaca ttaagcatac caattatact ggtaactgca tctgatattt ctacagaaat
    19381 cataagctgt ttatctttat cattcgtatc caagtcaaaa cgctctcgtc tagtataaac
    19441 agcaacagtt ttaccactgc ttattttttc ctctacaact tttataactc tttttacctc
    19501 attttttaga ccattttctt gaagaactaa atgttgatta aattctataa attctatcgg
    19561 atatttacaa tttttaagtt cttctaactg ttgggtagtc ttattcacat gtgaaccaac
    19621 aagtataatt cctccattgg tattaccttt tgatactaat tcatccttag taagtagttc
    19681 cttgtcactc actccgccaa gtacttttgt tatggcagca gcgcttctaa acataaattc
    19741 cttaccacca tttactgctc gtataaacgc aattgtaaat acctttacat ctacataatc
    19801 ggttgcattt acaataattt tattgaatcc ttcagctttt ttaagttttt ctgttatagc
    19861 ttcaatattt agctctctaa gttcttttga cgaaatatat atcatatcac tagatttgta
    19921 ctttccattt gtcttttctt cacaccactc acctatatca gatgatttat atccaaaaga
    19981 tttatctttt gcaaattcag tcattcctgc tggtacaagt atttctcctt ctttaacata
    20041 atgtacatta tctatagtaa acctaccacc ttctttaaaa aatggcatta ttatttcacc
    20101 ctgaaataac ttccccgata atctctctac ttcgcttttt aata
//
