Select genomic region:
Overview
1.1
1.2
1.3
1.4

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP076401.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | NRPS | 1,449,954 | 1,492,143 |
Region 1.2 | ranthipeptide,cyclic-lactone-autoinducer | 2,978,255 | 2,999,276 |
Region 1.3 | ranthipeptide | 3,053,252 | 3,073,395 |
Region 1.4 | cyclic-lactone-autoinducer | 3,727,268 | 3,748,048 |

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | NRPS | 1,449,954 | 1,492,143 |
Region 1.2 | ranthipeptide,cyclic-lactone-autoinducer | 2,978,255 | 2,999,276 |
Region 1.3 | ranthipeptide | 3,053,252 | 3,073,395 |
Region 1.4 | cyclic-lactone-autoinducer | 3,727,268 | 3,748,048 |

No secondary metabolite regions were found in these records:
  NZ_CP076402.1

Compact view
NZ_CP076401.1 - Region 1 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,449,954 - 1,492,143 nt. (total: 42,190 nt) Show pHMM detection rules used
NRPS: cds(Condensation and (AMP-binding or A-OX))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | NRPS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000600.1 |  | 0.19 | RiPP | thurincin H | Bacillus thuringiensis
BGC0000349.1 |  | 0.18 | NRP | erythrochelin | Saccharopolyspora erythraea NRRL 2338
BGC0001479.1 |  | 0.18 | NRP | anabaenopeptin NZ857, nostamide A | Nostoc punctiforme PCC 73102
BGC0001844.1 |  | 0.18 | NRP | holrhizin | Paraburkholderia rhizoxinica HKI 454
BGC0001135.1 |  | 0.18 | NRP | bicornutin A1, bicornutin A2 | Xenorhabdus budapestensis
BGC0001758.1 |  | 0.18 | NRP | rhizomide A, rhizomide B, rhizomide C | Paraburkholderia rhizoxinica HKI 454
BGC0001131.1 |  | 0.18 | NRP | ambactin | Xenorhabdus miraniensis
BGC0001767.1 |  | 0.18 | NRP | salinichelins | Salinispora pacifica CNY331
BGC0001833.1 |  | 0.18 | NRP | icosalide A, icosalide B | Burkholderia gladioli
BGC0001128.1 |  | 0.18 | NRP | luminmide | Photorhabdus laumondii subsp. laumondii TTO1

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000600.1 |  | 0.51 | RiPP | thurincin H | Bacillus thuringiensis
BGC0000349.1 |  | 0.50 | NRP | erythrochelin | Saccharopolyspora erythraea NRRL 2338
BGC0001479.1 |  | 0.49 | NRP | anabaenopeptin NZ857, nostamide A | Nostoc punctiforme PCC 73102
BGC0001844.1 |  | 0.49 | NRP | holrhizin | Paraburkholderia rhizoxinica HKI 454
BGC0001135.1 |  | 0.49 | NRP | bicornutin A1, bicornutin A2 | Xenorhabdus budapestensis
BGC0001758.1 |  | 0.49 | NRP | rhizomide A, rhizomide B, rhizomide C | Paraburkholderia rhizoxinica HKI 454
BGC0001131.1 |  | 0.49 | NRP | ambactin | Xenorhabdus miraniensis
BGC0001767.1 |  | 0.49 | NRP | salinichelins | Salinispora pacifica CNY331
BGC0001833.1 |  | 0.49 | NRP | icosalide A, icosalide B | Burkholderia gladioli
BGC0001128.1 |  | 0.49 | NRP | luminmide | Photorhabdus laumondii subsp. laumondii TTO1

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP076401.1 - Region 2 - cyclic-lactone-autoinducer,ranthipeptide
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,978,255 - 2,999,276 nt. (total: 21,022 nt) Show pHMM detection rules used
ranthipeptide: (TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085 or SPASM)) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716 or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or YcaO or TIGR03882)))
cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | ranthipeptide | cyclic-lactone-autoinducer | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | --- | ---
BGC0001387.1 |  |  | 0.36 | Other | nucleocidin | Streptomyces calvus
BGC0001935.1 |  |  | 0.18 | Other | 3,7-dihydroxytropolone | Streptomyces cyaneofuscatus
BGC0001487.1 |  |  | 0.18 | Other | 3,7-dihydroxytropolone | Streptomyces cyaneofuscatus
BGC0001943.1 |  |  | 0.09 | NRP | vioprolides A, vioprolides B, vioprolides C, vioprolides D | Cystobacter sp.
BGC0001822.1 |  |  | 0.09 | NRP | vioprolide A | Cystobacter sp.
BGC0001704.1 |  |  | 0.09 | Other | nocuolin A | Nodularia sp. HBU26
BGC0001591.1 |  |  | 0.09 | Other | fatty acid enol ester | uncultured bacterium CSLC2
BGC0001688.1 |  |  | 0.09 | Other | N-tetradecanoyl tyrosine | uncultured bacterium CSLC2
BGC0001358.1 |  |  | 0.08 | Polyketide | leucinostatin A, leucinostatin B | Purpureocillium lilacinum
BGC0001703.1 |  |  | 0.08 | Other | nocuolin A | Nostoc sp. CCAP 1453/38

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001387.1 |  | 0.50 | Other | nucleocidin | Streptomyces calvus
BGC0001935.1 |  | 0.38 | Other | 3,7-dihydroxytropolone | Streptomyces cyaneofuscatus
BGC0001487.1 |  | 0.38 | Other | 3,7-dihydroxytropolone | Streptomyces cyaneofuscatus
BGC0001943.1 |  | 0.24 | NRP | vioprolides A, vioprolides B, vioprolides C, vioprolides D | Cystobacter sp.
BGC0001822.1 |  | 0.24 | NRP | vioprolide A | Cystobacter sp.
BGC0001591.1 |  | 0.23 | Other | fatty acid enol ester | uncultured bacterium CSLC2
BGC0001688.1 |  | 0.23 | Other | N-tetradecanoyl tyrosine | uncultured bacterium CSLC2
BGC0001704.1 |  | 0.22 | Other | nocuolin A | Nodularia sp. HBU26
BGC0000027.1 |  | 0.22 | Polyketide | ankaflavin, monascin, rubropunctatine, monascorubrin | Monascus pilosus
BGC0001358.1 |  | 0.20 | Polyketide | leucinostatin A, leucinostatin B | Purpureocillium lilacinum

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP076401.1 - Region 3 - ranthipeptide
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 3,053,252 - 3,073,395 nt. (total: 20,144 nt) Show pHMM detection rules used
ranthipeptide: (TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085 or SPASM)) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716 or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or YcaO or TIGR03882)))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

No matches found.

No matches found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP076401.1 - Region 4 - cyclic-lactone-autoinducer
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 3,727,268 - 3,748,048 nt. (total: 20,781 nt) Show pHMM detection rules used
cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | cyclic-lactone-autoinducer | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000484.1 |  | 0.21 | RiPP | glycocin F | Lactobacillus plantarum
BGC0000488.1 |  | 0.17 | RiPP | circularin A | Clostridium beijerinckii
BGC0000616.1 |  | 0.16 | RiPP | amylocyclicin | Bacillus velezensis FZB42
BGC0000528.1 |  | 0.16 | RiPP | michiganin A | Clavibacter michiganensis subsp. michiganensis NCPPB 382
BGC0000571.1 |  | 0.16 | RiPP | burhizin | Paraburkholderia rhizoxinica HKI 454
BGC0000643.1 |  | 0.16 | Terpene | carotenoid | Brevundimonas vesicularis
BGC0000522.1 |  | 0.16 | RiPP | lacticin Z | Lactococcus lactis
BGC0000634.1 |  | 0.15 | Terpene | carotenoid | Brevundimonas sp. SD212
BGC0001289.1 |  | 0.15 | RiPP | penisin | Paenibacillus ehimensis
BGC0000500.1 |  | 0.15 | RiPP | carnolysin A1, carnolysin A2 | Carnobacterium maltaromaticum

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000484.1 |  | 0.54 | RiPP | glycocin F | Lactobacillus plantarum
BGC0000488.1 |  | 0.49 | RiPP | circularin A | Clostridium beijerinckii
BGC0000616.1 |  | 0.47 | RiPP | amylocyclicin | Bacillus velezensis FZB42
BGC0000528.1 |  | 0.47 | RiPP | michiganin A | Clavibacter michiganensis subsp. michiganensis NCPPB 382
BGC0000571.1 |  | 0.46 | RiPP | burhizin | Paraburkholderia rhizoxinica HKI 454
BGC0000643.1 |  | 0.46 | Terpene | carotenoid | Brevundimonas vesicularis
BGC0000522.1 |  | 0.46 | RiPP | lacticin Z | Lactococcus lactis
BGC0000634.1 |  | 0.46 | Terpene | carotenoid | Brevundimonas sp. SD212
BGC0001289.1 |  | 0.46 | RiPP | penisin | Paenibacillus ehimensis
BGC0000500.1 |  | 0.46 | RiPP | carnolysin A1, carnolysin A2 | Carnobacterium maltaromaticum

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names