LOCUS       NC_009495.1            23755 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_009495.1 Clostridium botulinum A str. ATCC 3502, complete
            sequence.
ACCESSION   NC_009495
VERSION     NC_009495.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:33:46
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 566455
            Orig. end    :: 590210
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23755
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[576455:580210]"
                     /cutoff="20000"
                     /detection_rule="((((goadsporin_like or PF00881 or
                     TIGR03605) and (YcaO or TIGR03882 or TIGR03604)) or
                     TIGR03603 or TIGR03602) and not cyanobactin_synth)"
                     /neighbourhood="10000"
                     /product="LAP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13755
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((((goadsporin_like or PF00881 or
                     TIGR03605) and (YcaO or TIGR03882 or TIGR03604)) or
                     TIGR03603 or TIGR03602) and not cyanobactin_synth)"
                     /neighbourhood="10000"
                     /product="LAP"
                     /protocluster_number="1"
     cand_cluster    1..23755
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((((goadsporin_like or PF00881 or
                     TIGR03605) and (YcaO or TIGR03882 or TIGR03604)) or
                     TIGR03603 or TIGR03602) and not cyanobactin_synth)"
                     /kind="single"
                     /product="LAP"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..23755
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="LAP"
                     /region_number="2"
                     /rules="((((goadsporin_like or PF00881 or TIGR03605) and
                     (YcaO or TIGR03882 or TIGR03604)) or TIGR03603 or
                     TIGR03602) and not cyanobactin_synth)"
                     /tool="antismash"
     CDS             2091..2327
                     /locus_tag="ctg1_466"
                     /transl_table=11
                     /translation="LASPNNLNSLLKAKEKALPKGFNEARFLQNCMTVLKDIKNIEKCN
                     EVSVVRTMLKGVFLGLDFFNKECYAIPVYLNLF"
     PFAM_domain     2163..2309
                     /aSDomain="RecT"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03837.16"
                     /description="RecT family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_466_0024"
                     /evalue="1.40E-08"
                     /label="ctg1_466"
                     /locus_tag="ctg1_466"
                     /protein_end="73"
                     /protein_start="24"
                     /score="34.5"
                     /tool="antismash"
                     /translation="ARFLQNCMTVLKDIKNIEKCNEVSVVRTMLKGVFLGLDFFNKECY
                     AIPV"
     CDS             2404..2499
                     /locus_tag="ctg1_467"
                     /transl_table=11
                     /translation="MKGELEFIRCGKYDYCKITKELKEIIHYKKL"
     CDS             3208..3555
                     /locus_tag="ctg1_468"
                     /transl_table=11
                     /translation="MTPIEIMEKIGACQRGLTKGNIELKALGVKKARAEHDYRIALRKE
                     ILRLRQLENQPATIINDLAKGKEDIAKLRLERDIAETNYSVYIESMRNLRLEIEAYRSF
                     LTWERVELKNT"
     CDS             complement(3574..3723)
                     /locus_tag="ctg1_469"
                     /transl_table=11
                     /translation="MSNLNSLELQNLPHLIGAHETIADKLNKIRVKQSIIIYIRKEEVF
                     FTSL"
     CDS             4241..5050
                     /locus_tag="ctg1_470"
                     /transl_table=11
                     /translation="LKISNIKEITLFEHHFWLQILGDHSRFILNSLSPKEKSFIEEANR
                     FKNLFDNLLKKSKQSLSEEELFALNNHAYNAAMKIREFKLDIIDRQITDKIVISLPPTF
                     INHMVNEVDEYIFILTKLMKGNVSNIGPIHLHLLWLPDGAGHASNIASSLDITEKELIK
                     KSNQYSKKFNNLYLRTIEYNGYTRTGICDFPALDSLNNNADETMSCFKEFLNELKKGVI
                     EKKILGTIVPLVPDHMFREECYYLTKLSMVSNIKKPECDPTKSRVES"
     PFAM_domain     4271..4597
                     /aSDomain="DUF2935"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF11155.10"
                     /description="Domain of unknown function (DUF2935)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_470_0025"
                     /evalue="8.50E-26"
                     /label="ctg1_470"
                     /locus_tag="ctg1_470"
                     /protein_end="119"
                     /protein_start="10"
                     /score="90.9"
                     /tool="antismash"
                     /translation="LFEHHFWLQILGDHSRFILNSLSPKEKSFIEEANRFKNLFDNLLK
                     KSKQSLSEEELFALNNHAYNAAMKIREFKLDIIDRQITDKIVISLPPTFINHMVNEVDE
                     YIFIL"
     PFAM_domain     4634..4987
                     /aSDomain="DUF2935"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF11155.10"
                     /description="Domain of unknown function (DUF2935)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_470_0026"
                     /evalue="3.60E-32"
                     /label="ctg1_470"
                     /locus_tag="ctg1_470"
                     /protein_end="249"
                     /protein_start="131"
                     /score="111.5"
                     /tool="antismash"
                     /translation="PIHLHLLWLPDGAGHASNIASSLDITEKELIKKSNQYSKKFNNLY
                     LRTIEYNGYTRTGICDFPALDSLNNNADETMSCFKEFLNELKKGVIEKKILGTIVPLVP
                     DHMFREECYYLTKL"
     CDS             6007..7383
                     /locus_tag="ctg1_471"
                     /transl_table=11
                     /translation="LKLTYVLDTNVILYSPGAIFSFADNDVVIPEVVLEELDSFKKNNY
                     DLGANARHAARIIDKLRKDGSLIDGIVLPGGGTLRVEMNHYDVKLPPSWDKNKPDNRII
                     QVCKGLKEKGEEVVLITKDTFERIKADTINIDVEDFYEKVVPEYESQYKGRCDAFASHS
                     TLESFYKNKYMDVESLFFYSEEKNDYYKADININEFILIKSMENPKQTALGRYNGEKVV
                     PLFYKDVKPLGISPRNIGQKFMLEAFLTDSKNAPLVIVKGPAGTAKTLFSLATGLHKVM
                     EEGEDGYRKILICRPNVTMDEDIGFLPGTEEEKIMPFMRPIFDNLEILVDSDEKERYKN
                     EKELYDKIKELFDRRIITTEAVAYLRGRSIVKNWVIIDEAQNLTPKQVKAVITRVGQGT
                     KLILVGDPDQIDQPFLDSRSNGLCYASEKMKGSKLCYQVTLKDHECERSPLAYEGAKRL
                     "
     PFAM_domain     6019..6426
                     /aSDomain="PIN_4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13638.8"
                     /description="PIN domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_471_0027"
                     /evalue="1.60E-33"
                     /label="ctg1_471"
                     /locus_tag="ctg1_471"
                     /protein_end="140"
                     /protein_start="4"
                     /score="115.9"
                     /tool="antismash"
                     /translation="YVLDTNVILYSPGAIFSFADNDVVIPEVVLEELDSFKKNNYDLGA
                     NARHAARIIDKLRKDGSLIDGIVLPGGGTLRVEMNHYDVKLPPSWDKNKPDNRIIQVCK
                     GLKEKGEEVVLITKDTFERIKADTINIDVEDF"
     PFAM_domain     6706..7359
                     /aSDomain="PhoH"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02562.18"
                     /description="PhoH-like protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_471_0028"
                     /evalue="2.00E-48"
                     /label="ctg1_471"
                     /locus_tag="ctg1_471"
                     /protein_end="451"
                     /protein_start="233"
                     /score="164.7"
                     /tool="antismash"
                     /translation="ISPRNIGQKFMLEAFLTDSKNAPLVIVKGPAGTAKTLFSLATGLH
                     KVMEEGEDGYRKILICRPNVTMDEDIGFLPGTEEEKIMPFMRPIFDNLEILVDSDEKER
                     YKNEKELYDKIKELFDRRIITTEAVAYLRGRSIVKNWVIIDEAQNLTPKQVKAVITRVG
                     QGTKLILVGDPDQIDQPFLDSRSNGLCYASEKMKGSKLCYQVTLKDHECERSPLA"
     CDS             7651..8655
                     /locus_tag="ctg1_472"
                     /transl_table=11
                     /translation="MENKEKKSKNKKFSFKIFLYFIIFELFFTAATAPFIIFHGPFKNV
                     KKTMVGAAMTTLKHQYIAKTFLSDAKIKEILGEDSIQTIKQDKNSVLKFENKHDSTIER
                     YDISYGKKFKGYMLVVHDPSRVKVGYSSKLPVQGELTSQIARNKRAVAAINAGGFTDKS
                     ANSKWTGTGGNVEGVIISKGEVKYNSNKQGEFTGDVAAITKKGALVVGKHSIQELKDLN
                     VQEAITFGPALVVKGQGTITSGDGGWGMAPRTAIGQREDGAILMLVIDGRQASSLGATL
                     KDVQDIMLQYDAYTATNLDGGSSTTMYHEGEVINNPANSLGERSVPSILYVEP"
     PFAM_domain     8095..8646
                     /aSDomain="NAGPA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09992.11"
                     /description="Phosphodiester glycosidase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_472_0029"
                     /evalue="1.40E-47"
                     /label="ctg1_472"
                     /locus_tag="ctg1_472"
                     /protein_end="332"
                     /protein_start="148"
                     /score="162.1"
                     /tool="antismash"
                     /translation="RAVAAINAGGFTDKSANSKWTGTGGNVEGVIISKGEVKYNSNKQG
                     EFTGDVAAITKKGALVVGKHSIQELKDLNVQEAITFGPALVVKGQGTITSGDGGWGMAP
                     RTAIGQREDGAILMLVIDGRQASSLGATLKDVQDIMLQYDAYTATNLDGGSSTTMYHEG
                     EVINNPANSLGERSVPSILYV"
     CDS             8665..9681
                     /locus_tag="ctg1_473"
                     /transl_table=11
                     /translation="MKVVKKIILWVMISLTLQFAGLFYIDKYFLASGGTRIKAKKVTNT
                     GTENKDYDVNIPENVEELDVSFNGKYISYFKDNKLNIISTKNGEKKNIEFDSKKDKLEY
                     IWLSDRNRIIYAENKEGQVLLNSYDVDKDQKDKICEFNFESSSAKIEDIKAAPLMNLIY
                     VKVNVGGNNNRLYSVNIMKEKDRIDIMTEAVGDMNIIPHEDILIYEDKINKKIFATHNE
                     SSINIGGVTSPKLLSIDDNDNVYIGELKEDEVVKIYYGNVKNNTSTWKALDIPNGAKVK
                     DIYVSPLGSVYVNDDLKGVIKEISTGKETKYSGVMMKMYIDGVASISDGKLVKTKFK"
     aSDomain        10001..10168
                     /aSDomain="TIGR03602"
                     /aSTool="tigrfam"
                     /description="streptolysinS: bacteriocin protoxin,
                     streptolysin S family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_474_0006"
                     /evalue="2.60E-33"
                     /identifier="TIGR03602"
                     /label="ctg1_474"
                     /locus_tag="ctg1_474"
                     /protein_end="56"
                     /protein_start="0"
                     /score="112.0"
                     /tool="antismash"
                     /translation="MLKFNEHVLTTTNNSNNKVTVAPGSCCCCSCCCCVSVSVGGGSAS
                     TGGGAAAGQGG"
     CDS             10001..10174
                     /gene_functions="biosynthetic (rule-based-clusters) LAP:
                     TIGR03602"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_474"
                     /sec_met_domain="TIGR03602 (E-value: 2.1e-33, bitscore:
                     112.0, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKFNEHVLTTTNNSNNKVTVAPGSCCCCSCCCCVSVSVGGGSAS
                     TGGGAAAGQGGN"
     CDS             10339..11295
                     /gene_functions="biosynthetic (rule-based-clusters) LAP:
                     PF00881"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_475"
                     /sec_met_domain="PF00881 (E-value: 3.5e-26, bitscore: 90.0,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLKNLKKQKVKKQRNTDIGNKMLVHFNTQYSSISPYVDSTVIKT
                     PDTIIKGSLYSKDNRFLSEEYLLNYRTNNDNLGFRMGVSSFFQKDAALTFVNLDMEEDG
                     QNVIELPPSKNIRVGLSTAIKSRRSVRGYSSKSMSLNDVANIFYYTQGICDEVEPYNLE
                     GNKKKIKLRANPSAGGLYPIQLYVYMKNIKDLKDGIYTYYPYSHGLKPIEVNKELLKVD
                     NFAEFGVLNAENANLIVFYVYNFLKNSRKYGDAGFSYALIETGEMAQNLQLVSTALGYG
                     ACDIGGYEKQYIEEVLDIDGVLKHVVHMTVVGWEQGD"
     PFAM_domain     10708..11280
                     /aSDomain="Nitroreductase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00881.26"
                     /description="Nitroreductase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_475_0030"
                     /evalue="2.20E-20"
                     /label="ctg1_475"
                     /locus_tag="ctg1_475"
                     /protein_end="314"
                     /protein_start="123"
                     /score="73.5"
                     /tool="antismash"
                     /translation="IKSRRSVRGYSSKSMSLNDVANIFYYTQGICDEVEPYNLEGNKKK
                     IKLRANPSAGGLYPIQLYVYMKNIKDLKDGIYTYYPYSHGLKPIEVNKELLKVDNFAEF
                     GVLNAENANLIVFYVYNFLKNSRKYGDAGFSYALIETGEMAQNLQLVSTALGYGACDIG
                     GYEKQYIEEVLDIDGVLKHVVHMTVVGW"
     aSDomain        10753..11280
                     /aSDomain="TIGR03605"
                     /aSTool="tigrfam"
                     /description="antibiot_sagB: SagB-type dehydrogenase
                     domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_475_0007"
                     /evalue="7.60E-60"
                     /identifier="TIGR03605"
                     /label="ctg1_475"
                     /locus_tag="ctg1_475"
                     /protein_end="314"
                     /protein_start="138"
                     /score="199.3"
                     /tool="antismash"
                     /translation="SLNDVANIFYYTQGICDEVEPYNLEGNKKKIKLRANPSAGGLYPI
                     QLYVYMKNIKDLKDGIYTYYPYSHGLKPIEVNKELLKVDNFAEFGVLNAENANLIVFYV
                     YNFLKNSRKYGDAGFSYALIETGEMAQNLQLVSTALGYGACDIGGYEKQYIEEVLDIDG
                     VLKHVVHMTVVGW"
     CDS             11299..12381
                     /gene_functions="biosynthetic (rule-based-clusters) LAP:
                     TIGR03603"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Cytolysin_C_RRE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_476"
                     /sec_met_domain="TIGR03603 (E-value: 8.7e-138, bitscore:
                     457.0, seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="Cytolysin_C_RRE (E-value: 1.7e-34,
                     bitscore: 115.7, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNNTIYRLSNNLRIYDNGENEIRFRSGLWNYNEAVLDLSAETEN
                     FTKSFRKVIDNLKNNKGISVKDLDGYELNNEEKNNLISIIDSLNEAGMLCSEDEKDNDF
                     AMSKVLLGDFSYNLNKKEENNQKLLFISDNDYAKQTAKNLSDGMNTNLDLYSKENIDNI
                     ISKDLTSNLDALEKKSNIEDIKNQLKDYSAILICMSHINMNLFRNINRVSIELKKPIIM
                     SFIDGPFITILSTLPPKTGCLECFEQRILSRLEDHVLYHKFIESDFKPSDKSHKSIIPL
                     LNIMTNMVISEGFLINNFNTCKIEGRVLSIFVPTLEIQSQDLLRVPFCPACGNISKAKL
                     KEINISTRNIVDGILEDINS"
     aSDomain        11386..12366
                     /aSDomain="TIGR03603"
                     /aSTool="tigrfam"
                     /description="cyclo_dehy_ocin: thiazole/oxazole-forming
                     peptide maturase, SagC family component"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_476_0008"
                     /evalue="1.10E-137"
                     /identifier="TIGR03603"
                     /label="ctg1_476"
                     /locus_tag="ctg1_476"
                     /protein_end="356"
                     /protein_start="29"
                     /score="457.0"
                     /tool="antismash"
                     /translation="WNYNEAVLDLSAETENFTKSFRKVIDNLKNNKGISVKDLDGYELN
                     NEEKNNLISIIDSLNEAGMLCSEDEKDNDFAMSKVLLGDFSYNLNKKEENNQKLLFISD
                     NDYAKQTAKNLSDGMNTNLDLYSKENIDNIISKDLTSNLDALEKKSNIEDIKNQLKDYS
                     AILICMSHINMNLFRNINRVSIELKKPIIMSFIDGPFITILSTLPPKTGCLECFEQRIL
                     SRLEDHVLYHKFIESDFKPSDKSHKSIIPLLNIMTNMVISEGFLINNFNTCKIEGRVLS
                     IFVPTLEIQSQDLLRVPFCPACGNISKAKLKEINISTRNIVDGILE"
     CDS             12397..13755
                     /gene_functions="biosynthetic (rule-based-clusters) LAP:
                     YcaO"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_477"
                     /sec_met_domain="YcaO (E-value: 5.6e-58, bitscore: 194.9,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKFSPSFNNILENFKSLAGNQSGILEAACMPVVNFNSDVSLKSI
                     TGNMPDYHKQVFNKDVSMQYHIMGYGSHYEEALIKYTGESIERYSSIMGPTLLKDKIVY
                     ESYKELSKNNKVMPLKYIDVFTENQIKKAKELNVSICDKKVEEDDIIGWIKCPSLLKKG
                     KEIYVPAKMMFVGYEEDKNKGEMTFIPSFSTGTAAHKSLKKALLNALVEYIQIDSFMIN
                     WHTKGKCSLVKIDDENVLKVLEDVNLGEKSPYEIIPLYMSLEECPIHNFGVFLRRKDNK
                     LPYLLFGIQGGLDASHALTRGIMEAASISYGAYFNAIYNKDMLNNVIKDDHKFLDLDSN
                     VLYYSLPNKIEEKNKLIEDFIGDEITLSSLNKLNIKGVDEQIKTLLNYLKDISEYAVYL
                     DLTPPETRDKGWYVMRAMIPELIEMCIPEFPFENHPRMKKYGGVINEYPHPMP"
     PFAM_domain     12598..13659
                     /aSDomain="YcaO"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02624.18"
                     /description="YcaO cyclodehydratase, ATP-ad Mg2+-binding"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_477_0031"
                     /evalue="1.80E-47"
                     /label="ctg1_477"
                     /locus_tag="ctg1_477"
                     /protein_end="421"
                     /protein_start="67"
                     /score="162.4"
                     /tool="antismash"
                     /translation="MGYGSHYEEALIKYTGESIERYSSIMGPTLLKDKIVYESYKELSK
                     NNKVMPLKYIDVFTENQIKKAKELNVSICDKKVEEDDIIGWIKCPSLLKKGKEIYVPAK
                     MMFVGYEEDKNKGEMTFIPSFSTGTAAHKSLKKALLNALVEYIQIDSFMINWHTKGKCS
                     LVKIDDENVLKVLEDVNLGEKSPYEIIPLYMSLEECPIHNFGVFLRRKDNKLPYLLFGI
                     QGGLDASHALTRGIMEAASISYGAYFNAIYNKDMLNNVIKDDHKFLDLDSNVLYYSLPN
                     KIEEKNKLIEDFIGDEITLSSLNKLNIKGVDEQIKTLLNYLKDISEYAVYLDLTPPETR
                     DKGWYVMRAMIPEL"
     aSDomain        12601..13752
                     /aSDomain="TIGR03604"
                     /aSTool="tigrfam"
                     /description="TOMM_cyclo_SagD: thiazole/oxazole-forming
                     peptide maturase, SagD family component"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_477_0009"
                     /evalue="3.60E-111"
                     /identifier="TIGR03604"
                     /label="ctg1_477"
                     /locus_tag="ctg1_477"
                     /protein_end="452"
                     /protein_start="68"
                     /score="369.7"
                     /tool="antismash"
                     /translation="GYGSHYEEALIKYTGESIERYSSIMGPTLLKDKIVYESYKELSKN
                     NKVMPLKYIDVFTENQIKKAKELNVSICDKKVEEDDIIGWIKCPSLLKKGKEIYVPAKM
                     MFVGYEEDKNKGEMTFIPSFSTGTAAHKSLKKALLNALVEYIQIDSFMINWHTKGKCSL
                     VKIDDENVLKVLEDVNLGEKSPYEIIPLYMSLEECPIHNFGVFLRRKDNKLPYLLFGIQ
                     GGLDASHALTRGIMEAASISYGAYFNAIYNKDMLNNVIKDDHKFLDLDSNVLYYSLPNK
                     IEEKNKLIEDFIGDEITLSSLNKLNIKGVDEQIKTLLNYLKDISEYAVYLDLTPPETRD
                     KGWYVMRAMIPELIEMCIPEFPFENHPRMKKYGGVINEYPHPMP"
     CDS             13730..14368
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_478"
                     /sec_met_domain="Abi (E-value: 2.6e-11, bitscore: 41.5,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIRTQCLNLLILLVTFNPIVLAQLFLNNEKSYNESLKRSFKALA
                     IIYTIILTSIFIISKERFYINIDNNYYGYIIAVMFVPITIISEIAVGYIMLGISNKTIP
                     KFKISLVFTKTNINVIILSVFIGICEEFAYRQLWFNILFKDFKMNIAIVLIITSFVYAL
                     NHIFLGKQVFSQKMVAGLIYGALFYFSGFNIIVPIITHSLENIAILLKG"
     PFAM_domain     14081..14347
                     /aSDomain="Rce1-like"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02517.18"
                     /description="Type II CAAX prenyl endopeptidase Rce1-like"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_478_0032"
                     /evalue="5.30E-11"
                     /label="ctg1_478"
                     /locus_tag="ctg1_478"
                     /protein_end="206"
                     /protein_start="117"
                     /score="42.8"
                     /tool="antismash"
                     /translation="NVIILSVFIGICEEFAYRQLWFNILFKDFKMNIAIVLIITSFVYA
                     LNHIFLGKQVFSQKMVAGLIYGALFYFSGFNIIVPIITHSLENI"
     CDS             14376..15104
                     /locus_tag="ctg1_479"
                     /transl_table=11
                     /translation="MNLYLKILVFLLMTIYIVILYLPMNINYKKFKFTKKLCLNLSGAI
                     GTSPTNCWCLMKYVHLLIIGVIPIACFFYRGIVKNYSLYTETNIIKSFILIILSFIGIL
                     EISFFMIIVVVSYLMKKDSRKEMSNVSWVKFNKKYPFYTGILKPIMYTVFEILLYYYVM
                     FYVINDYLKVSVMYSILGIAILYSVSKLAFTKNKEQALIYGIWAFALNIIGSCIMIYSN
                     SIILTFILYLLYSFVIAFKE"
     PFAM_domain     14652..15101
                     /aSDomain="DUF5968"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF19393.1"
                     /description="Family of unknown function (DUF5968)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_479_0033"
                     /evalue="1.90E-69"
                     /label="ctg1_479"
                     /locus_tag="ctg1_479"
                     /protein_end="242"
                     /protein_start="92"
                     /score="232.7"
                     /tool="antismash"
                     /translation="FILIILSFIGILEISFFMIIVVVSYLMKKDSRKEMSNVSWVKFNK
                     KYPFYTGILKPIMYTVFEILLYYYVMFYVINDYLKVSVMYSILGIAILYSVSKLAFTKN
                     KEQALIYGIWAFALNIIGSCIMIYSNSIILTFILYLLYSFVIAFKE"
     CDS             15413..16345
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 218.2; E-value:
                     2e-66)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_480"
                     /transl_table=11
                     /translation="MNIVEIKNLEKKFKNNTAVNNINLTVKEGQVFGFLGPNGAGKSTT
                     INMICGLLTPTKGEIFILGKKMDNKAKDLKNNIGIVPQDIAIYEDLTAYENVAFFGGLY
                     GVRGQELKERAKETLEFVGLLDRAKDFPYKFSGGMKRRLNIACALVHQPKLIIMDEPTV
                     GIDPQSRNHILESIKKLNERGCTIIYTSHYIEEVEQLCTDIAIIDKGTIIAKGKKDELV
                     EKYSDLNMVVINIKDSTKVNIKALKSIEGVVEVNIKENTIEITNKSSDNLDDIIMYFLN
                     NKIKIKNIENKHSDLETIFLKLTGKKLRD"
     PFAM_domain     15467..15898
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_480_0034"
                     /evalue="1.10E-34"
                     /label="ctg1_480"
                     /locus_tag="ctg1_480"
                     /protein_end="162"
                     /protein_start="18"
                     /score="120.0"
                     /tool="antismash"
                     /translation="VNNINLTVKEGQVFGFLGPNGAGKSTTINMICGLLTPTKGEIFIL
                     GKKMDNKAKDLKNNIGIVPQDIAIYEDLTAYENVAFFGGLYGVRGQELKERAKETLEFV
                     GLLDRAKDFPYKFSGGMKRRLNIACALVHQPKLIIMDEPT"
     CDS             16357..17481
                     /locus_tag="ctg1_481"
                     /transl_table=11
                     /translation="MKILNILKKEILENFRDKKAMFLMTLFPMLLITILGTVFSGNFAS
                     TINIPEINVMYSINKDVKIDKNFKDFTKEIQKNMKVNFKETKEEKDALEKISNGKADVY
                     IKIPNDKKIYIYENNVRAFNSQLVSTLLDTFVDKVNMTKEVSSKNPMALSKIKVDNSPN
                     FVNTKTIDGKNSPRGIDYYAVTMLTMTILYGTAVGAMSIASEIKRRTYKRLICSNTSPL
                     KILFSKILASFLVIAFQSFLIYLFSKYILGTNWGNNKLALISVVASLIFMAVSAGVCIA
                     NTIKNEGVMSIIIYMFVPVLTFLGGGYIPLDTIGSKMLNSASNISPLKWSNDAIFKIIF
                     GNDLSIFGTTMLINLGAGVLFLLIAILFPRKDVV"
     PFAM_domain     16414..17457
                     /aSDomain="ABC2_membrane_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12698.9"
                     /description="ABC-2 family transporter protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_481_0035"
                     /evalue="8.40E-34"
                     /label="ctg1_481"
                     /locus_tag="ctg1_481"
                     /protein_end="367"
                     /protein_start="19"
                     /score="117.3"
                     /tool="antismash"
                     /translation="AMFLMTLFPMLLITILGTVFSGNFASTINIPEINVMYSINKDVKI
                     DKNFKDFTKEIQKNMKVNFKETKEEKDALEKISNGKADVYIKIPNDKKIYIYENNVRAF
                     NSQLVSTLLDTFVDKVNMTKEVSSKNPMALSKIKVDNSPNFVNTKTIDGKNSPRGIDYY
                     AVTMLTMTILYGTAVGAMSIASEIKRRTYKRLICSNTSPLKILFSKILASFLVIAFQSF
                     LIYLFSKYILGTNWGNNKLALISVVASLIFMAVSAGVCIANTIKNEGVMSIIIYMFVPV
                     LTFLGGGYIPLDTIGSKMLNSASNISPLKWSNDAIFKIIFGNDLSIFGTTMLINLGAGV
                     LFLLIAIL"
     CDS             17483..18625
                     /locus_tag="ctg1_482"
                     /transl_table=11
                     /translation="MKQIFLLTKSILKRTFRKKSNIITFILLPLLAVFIALFLNASGNS
                     YSKIGVVDLNESYLSKDMIKSIDAKKNFVVVKISKNNMNKLLLDKRVDCVVVIPKDFNK
                     DIIDGNFKKLDIISVRGEDITSWIKNYLNYYIDTLNNISVASNKNEKDFKAIYDGYKKQ
                     DLKLNYKAIGDKTKTKSVTKQSIGLLLVFMLIASSTASSFILKDKYNKTYYRIFCSNTS
                     KSKYIIANVIANFVIFLIQIFVILFMSIYVLKLNFYIDTSIMFIILCSFGFVSIGFGII
                     IAAFSKSLNQSSYLSNILITPTCMLSGCFWPLDMMPSFMQKLANIFPQTWVLKTIDSLQ
                     QGKSFNEVISYLGIVILFALAFFVVGILKLTKDENLKSIF"
     PFAM_domain     17543..18583
                     /aSDomain="ABC2_membrane_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12698.9"
                     /description="ABC-2 family transporter protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_482_0036"
                     /evalue="2.30E-37"
                     /label="ctg1_482"
                     /locus_tag="ctg1_482"
                     /protein_end="367"
                     /protein_start="20"
                     /score="129.0"
                     /tool="antismash"
                     /translation="NIITFILLPLLAVFIALFLNASGNSYSKIGVVDLNESYLSKDMIK
                     SIDAKKNFVVVKISKNNMNKLLLDKRVDCVVVIPKDFNKDIIDGNFKKLDIISVRGEDI
                     TSWIKNYLNYYIDTLNNISVASNKNEKDFKAIYDGYKKQDLKLNYKAIGDKTKTKSVTK
                     QSIGLLLVFMLIASSTASSFILKDKYNKTYYRIFCSNTSKSKYIIANVIANFVIFLIQI
                     FVILFMSIYVLKLNFYIDTSIMFIILCSFGFVSIGFGIIIAAFSKSLNQSSYLSNILIT
                     PTCMLSGCFWPLDMMPSFMQKLANIFPQTWVLKTIDSLQQGKSFNEVISYLGIVILFAL
                     AFFVVGI"
     CDS             18744..19403
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M50"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_483"
                     /sec_met_domain="Peptidase_M50 (E-value: 3.4e-08, bitscore:
                     30.8, seeds: 56, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSFLDLNYRILSKILIIPAILVGLTVHEFAHAYVADKLGDKTPKF
                     QGRLTLNPFSHIDIIGFIMILLIGFGWAKPVQINPSALKRGYKDEIKVSVAGVTANVIT
                     AFLFALLTAFLLKLNLVNFGDITSLGGIIGLILNYIVRINCMLAIFNLMPIPGLDGFDI
                     LRDLWPKTFYKISDVIYRYQMIILLIFVVTPISSFLVGIPTNFLHYSFMKIAMTIF"
     PFAM_domain     19146..19307
                     /aSDomain="Peptidase_M50"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02163.24"
                     /description="Peptidase family M50"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_483_0037"
                     /evalue="1.00E-07"
                     /label="ctg1_483"
                     /locus_tag="ctg1_483"
                     /protein_end="188"
                     /protein_start="134"
                     /score="31.6"
                     /tool="antismash"
                     /translation="LILNYIVRINCMLAIFNLMPIPGLDGFDILRDLWPKTFYKISDVI
                     YRYQMIILL"
     CDS             complement(19871..20341)
                     /locus_tag="ctg1_484"
                     /transl_table=11
                     /translation="MDNYMKVKNSMLTFLLEQMGAKIHRITGIVCYVEFTIDSVKIKYM
                     YHLDKKNKYFLERISPYNVTIGQFEKEEDVINTIKIDISKFENAKNSNKFNKFINTGKD
                     FVDIVKSFENLYLHYNVSKYDLADIQQNIDSLKEKLEEVSTKADVVYDKTTK"
     CDS             complement(20459..21721)
                     /locus_tag="ctg1_485"
                     /transl_table=11
                     /translation="MMLPAIIFIIVYALIISEKVNRVVASLGGAAIMLILKLITQEKAF
                     LKIDFNTIGLLVGMMIIVNITKRTGVFEYIAIKAAKFSKGNPIKILILFSVITAVLSGV
                     LDNVTTVLLIVPVTLVITKTLEIDPIPFLMCEIFASNIGGTATLIGDPPNLMIGSAAGL
                     SFLDFVKNLAPVIIIILTVTLLGIRQLYKNSMKTSEEDKKKIMALDESKAIRDMSLMKK
                     CLTVLFLTLIGFLTHSYLGFESATIAIAGSAILLAISKVEPDEILQETEWGTIFFFIGL
                     FIMTGVLEDVGIMEVLAQKTMSLTKGNLVMTGIFVLWISAIASAFIDNIPFVATMIPLI
                     KAMGTMGGMDIVPLWWALSLGACLGGNGTMIGASANLVVIGIAEKSGYKISFKDYFKLG
                     FPVMLVSIIICTAYLLMFFLK"
     PFAM_domain     complement(20639..21688)
                     /aSDomain="CitMHS"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03600.18"
                     /description="Citrate transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_485_0038"
                     /evalue="6.50E-57"
                     /label="ctg1_485"
                     /locus_tag="ctg1_485"
                     /protein_end="361"
                     /protein_start="11"
                     /score="193.1"
                     /tool="antismash"
                     /translation="YALIISEKVNRVVASLGGAAIMLILKLITQEKAFLKIDFNTIGLL
                     VGMMIIVNITKRTGVFEYIAIKAAKFSKGNPIKILILFSVITAVLSGVLDNVTTVLLIV
                     PVTLVITKTLEIDPIPFLMCEIFASNIGGTATLIGDPPNLMIGSAAGLSFLDFVKNLAP
                     VIIIILTVTLLGIRQLYKNSMKTSEEDKKKIMALDESKAIRDMSLMKKCLTVLFLTLIG
                     FLTHSYLGFESATIAIAGSAILLAISKVEPDEILQETEWGTIFFFIGLFIMTGVLEDVG
                     IMEVLAQKTMSLTKGNLVMTGIFVLWISAIASAFIDNIPFVATMIPLIKAMGTMGGMDI
                     VPLWWALSLG"
     CDS             complement(21848..23164)
                     /locus_tag="ctg1_486"
                     /transl_table=11
                     /translation="MSNFLEELKATKIISKNDIEKIKKFINIKYKNEDSKRKAYMVSST
                     IHNIIESKIDFFPKSIHKDLKNAILKNTFLNNKDSIYLWDIFYSYIDYVDFKKENIKIL
                     LNWININIKNKTDEESLVNYFYTNSLLKNHEKNGEIKTSSSSSSSSSSSSSSSSSSSSS
                     SSSSSKDSSTKIADEQPYIKIKKVDSIYLQNAHTESNNNFINIKQNTANITNNKYNTKS
                     ITKKFNIDFLYKNNIFKLYNNSITFALTILFISSISIYLFNMDTSIKTNSKNIIVYENK
                     NVKTKKNNILDKNKHLPQYVKYKTLNNEKLKKYLYTKNSLLADEPYFSSIISSAEEFDI
                     NPLILFAITGQEQGFVPKSNKSAKKIGNNPFNVFHSWEEYNSDIKDSSRIAGRTVFNLL
                     KTMPKGQDPFKWVNNTYAEDINWWKGVKSLFNELEKAVK"
ORIGIN
        1 gatatagaag tagtttctcc agaagatatt aatatagatg atattataat ggtaaaacca
       61 ggagaaaaaa ttcctctaga tggtatagtt gtagaaggac aatcttttgt agatacatca
      121 gctataacag gtgaatcttt aataagtgaa gtttcaaaag atagtaatgt attaagtgga
      181 tatataaaca aaaatggtgt tataaaaata aaagttacaa aaacctttgg agaatctaca
      241 gtgtccaaaa tattggaatt aacagaaaac gcatcagcta ctaaggcaaa tacagaaaaa
      301 tttataacaa agttcgccag atattatact cctgtagttg tttttgctgc tttagcttta
      361 gcagtaattc ctacactaat actaaaagat ccagatatat ctaaatggat ttatagagca
      421 gctgtatttt tagtagtatc ttgtccatgt gctttagtaa tatcaatacc tttaagcttc
      481 tttgctggta ttggaggggc atctaaaaaa ggtgttttaa taaaagcagg aacagcatta
      541 gaagctctaa atgatgcaga tacaatagta tttgataaaa caggaacttt aactaaaggt
      601 gtgtttaaag tatcaaaaat tgattcagaa gaaggagtaa atacagaaga attaatagaa
      661 tatgctgctt atgtagaaag ttattctaat caccctatcg caaaatctat actaaagtat
      721 tatgaaaaaa ccatagataa taaaagaata gaaggttatg aagaaatagt tgcaagaggt
      781 gtaactgctt atattgatgg caaaaaagtt tatgctggta acaataaatt aatggaagaa
      841 ttaaatatta actataaaaa agctcaagag gatggagtaa tcctttatat agcattagaa
      901 gataagtata taggttatat agttataaac gacgaaataa agaaagattc aaaagaaaca
      961 ataaaatcat taaaagatat aggtataaaa aaagcagcta tgcttacagg agatagaaaa
     1021 tctacagcta ataatatagg gacttttcta ggaatggatg aaatatactc agaactttta
     1081 ccacaggaaa aggtagaaaa gatgcaatcc ttaaagtcca aaacatctaa agatgggaaa
     1141 attgtttttg taggggatgg agtaaatgat gctccagtat tagctatgtc agatataggg
     1201 gtatccatgg gaggcttagg atctgatgca gccatagaag catctgattt agttttaatg
     1261 tctgatgaac catcaaaatt agtagatgcc ataaaaatag ctagaaaaac tcataaaata
     1321 gtatggcaaa atataattat agttttaata atcaagtttg cagtattagc tctagctgta
     1381 atgggaaaaa gtactatgtg gatggctgtt tttgccgatg taggtgtggc tttaatagca
     1441 gtaataaatg cattaagaat actaaaataa gaatttacta aaataataac tttctaaaga
     1501 aggataggaa cgaataattt taaagaaaaa tatttaatta tatttatata gttttagtta
     1561 agtagtttta ggttcagatg gagtttgctt agaataatta tttttctcca tctgaacatt
     1621 attatttatc agagagtaat aaatatagaa gattaatttt tatgaaagta taaaaaatta
     1681 tcaaattgta taaacaaagt atacttatga gaaattataa gatgagtatt aggtacttct
     1741 atatattctt caataaatgt tatgtaaaaa taaaagattt aataatttaa taaaaaaatt
     1801 aaaaacaaaa gaaaatattt ctaaaaaata ttgacttaaa atttaggctg taatataatt
     1861 atatatgttc aaagaaaata aataattgag gcttcttggt caagcggtta agacgccacc
     1921 ctctcacggt ggaatcaggg gttcgactcc cctaggagct accagatttg aagaaatgct
     1981 gtaaacagtg atgtttacag catttcttat ttagaagtga aaatggaaaa ttaatatttt
     2041 cccacactag aaaaatacaa atataaactt cctttctaat caaatttcca ttggcatccc
     2101 ccaataattt aaatagtttg ttaaaggcta aagaaaaagc tttaccaaaa ggatttaatg
     2161 aagctagatt tttacaaaat tgcatgacag tattaaaaga tattaaaaat atagaaaaat
     2221 gtaatgaagt gagtgtagta agaacaatgc ttaaaggagt atttctaggt ttagacttct
     2281 ttaataagga atgttatgca ataccagttt atttaaatct tttttagaag aatataatgg
     2341 atgtgaagct aggatgatgg cagtattaaa tgtatccatg aaaatataaa gagttaaaaa
     2401 agtatgaaag gtgaattaga gtttattaga tgtggtaaat atgattattg caagattact
     2461 aaagaattaa aagaaattat acactataaa aaattataag aggggtaata aagtggcagg
     2521 tacaacctca tatatagata aagaaacaaa agtaaatatt taagaggatg atgatttttt
     2581 tgttaaaatt cacaagttat ttgatgaata tgctttaagt attattggaa gaagagaagt
     2641 tcctcaaaaa gtatatgatg ttctaccaag taatttatct gattgtccaa tctatagtga
     2701 actagaagaa cagttaataa ataaagagtt gcttttataa gaagcataaa gtcaaattga
     2761 atgtttaaaa gatataatag attttttaaa aagataacac taccgtagta gaaattaata
     2821 tggcaagata agtgaaagcc tggataagtt tatatagaag tatacaagag cattggttat
     2881 agcaagagaa gcttttttca aaaagacagg catgactgaa cattattttc ttagagaatg
     2941 aattgataat tggtgcaaga ggtagcttca taacatcacc aaaaaagttg atccaaaaat
     3001 ggggatgggg ttataaaaag accagaagat ttttaaaaag aagcgttatg taatactata
     3061 tttggattaa aagatttaaa ataggtaata ctacatttac attaaaagac ttaaaacaag
     3121 tggtatagga actagtacaa gcggaagaag ttatagagaa attaaaataa attacaggat
     3181 ttatatccct gatgataagg aggaaatatg acaccgatag aaataatgga aaagataggg
     3241 gcatgtcaac gggggctgac gaaagggaat atagaattaa aagctttagg agtgaagaag
     3301 gctagagcag aacatgacta taggatagct ctaagaaaag agattttaag attaagacag
     3361 ttagagaatc agccagcaac aataataaat gacttagcta aaggaaaaga agatattgca
     3421 aaattaagac ttgaaaggga tatagcagaa actaattaca gtgtatatat agaaagtatg
     3481 aggaatttaa gattagagat tgaggcgtat agaagttttc tcacatggga acgtgtagaa
     3541 cttaaaaata cgtaatgtta aaattatgat gaactaaaga gaggtaaaga agacctcttc
     3601 ttttctgatg taaattatta ttgattgctt aactctgatt ttatttaatt tatctgctat
     3661 tgtttcatgt gcaccaataa gatgaggaag attttgtaat tctagtgagt ttaaatttga
     3721 cataaaatca cctctttaat aattagttca ataatattat tggaaagaga attaaaaatt
     3781 atacagtgat gtttaatact taaatataaa gttgagtgag ctcatggcaa aattcaaata
     3841 ttgaactaag ataaaagata agcttgtatt agctgaagaa agggcaagaa atgaagtaag
     3901 taatggacaa ataacaaaga atctagggat agataagggt atattttata aatataaaaa
     3961 gcaagtatat aggatttttt atatcttaga aagggggaag gagataatga tgatagattt
     4021 tggaattaaa gattcatttt taaaaagaac attagaatat aagtataagg aagtaaccaa
     4081 ggaattagta taagatcata ggactaaatt gtatacatat ataataactt tgatcattat
     4141 taaatatgta taataaataa taaatatatc agtaacataa tgttgtttgt gaacatatta
     4201 tattaagtaa tatagattag aaatattttg gagggtaact ttgaagatta gtaatattaa
     4261 agaaataaca ttatttgagc atcatttttg gttacagatt ttaggagatc attctagatt
     4321 tattttaaac tcactctcac caaaagaaaa atcttttatt gaagaagcaa acagatttaa
     4381 aaatttattt gataatttat taaagaaatc aaaacaatca ctttcagaag aagagctttt
     4441 cgctttaaat aatcatgcct ataatgcagc tatgaaaatt agagagttta agctagatat
     4501 aattgatagg cagattacag ataaaattgt catttcattg ccacctacat ttattaatca
     4561 tatggttaac gaagttgatg aatatatatt tatattaact aaattaatga aaggaaatgt
     4621 atctaatata ggacctattc atctccatct tttatggctt ccagatggag caggtcatgc
     4681 atccaatata gctagtagtc ttgatataac ggagaaagaa ttgattaaaa agagtaatca
     4741 atattctaaa aaatttaata atttatactt aaggactata gagtacaatg gttatacaag
     4801 aactggtatt tgtgatttcc cagcacttga tagtctaaat aataatgctg acgaaacaat
     4861 gagttgtttt aaagaatttt taaatgaatt aaagaaaggt gtcatagaaa agaaaatact
     4921 tggaactatt gtaccactag tacccgatca tatgtttaga gaagaatgtt actatttaac
     4981 taagctttca atggtttcaa acataaaaaa acccgaatgt gatcctacaa aatcaagagt
     5041 agagagctaa atttaacaaa gcaaaagagt catattttat tatctaaggt tcttttggta
     5101 tgattttatt atatagattg atgtagtata ttagtttatt tttattatac caaggtataa
     5161 taatcctaat cataaagtta tcaacaatat gcataataaa agggtgacaa ttacaatatt
     5221 gtcacctgaa tttttcctac accagtttga aattatcatg atttgatgaa aaatcctata
     5281 aatttcaaac ttagtaatat caatgaatag aagtatttat aaattttata aagacaaatt
     5341 aaaagggagc tattcaaaaa gctacaattt agtaatataa atgactgtag ctttttatta
     5401 tgttttttat atagaatttt taatataaat tattaataag gcttgcttag ttgaaaatta
     5461 gaaattgagt tttaaatatt tataatccta ttacattcat ttgcaatatt tttatcatag
     5521 gttactatta caattgtttt tcctttttta tttaaaagtt ttaatagacc tattatttta
     5581 taggaatttt cttcgtccag tgagccagta ggttcatctg ctaatattgt tattaggaag
     5641 gattagaaaa aatattgaca ggtcttaaga ggtgatgtat agttttatta agcggtataa
     5701 tttactactt aataaaacta tttttactat ttattattat attatatagg ggacattctt
     5761 atttacgcct ctttatttta tttttattta aaaggatttc tattgatata tagaggtcct
     5821 tttttattta aaagattttt gttaatataa aaattttttt atttcaaatc atatatataa
     5881 caaattaaat aatttagaaa atataatatt aaaagtctat aaatattttt aatttaataa
     5941 aatagagaat ttaataaagt tataacttta tctgaatata ataatataaa gagaggagga
     6001 gtagacttga aactaactta tgtattagat actaatgtta ttttgtattc accaggagct
     6061 atattttctt ttgcagataa tgatgtagtt atacctgaag tagttttaga agaattagat
     6121 agctttaaaa agaataatta tgatttaggg gctaatgcta ggcatgcagc aagaataata
     6181 gataaattaa gaaaagatgg aagtttaata gatggtatag tattacctgg tggaggaact
     6241 ttaagagtag aaatgaatca ttatgatgta aaattgcctc cgtcttggga taagaataag
     6301 ccggataaca gaataataca ggtttgtaag ggattaaaag aaaaagggga agaagtagta
     6361 ttaattacaa aggatacctt tgagaggata aaggcggata ctattaatat agatgtagag
     6421 gatttttatg aaaaggtagt accagaatat gaaagtcaat ataaaggaag atgtgatgct
     6481 tttgcatctc acagtacttt agaaagtttt tataaaaata aatatatgga tgtagagagc
     6541 ttattttttt attcagaaga gaaaaatgat tactataaag cagatatcaa tataaatgaa
     6601 tttatattaa ttaaatctat ggaaaatcca aaacaaacag ctctgggaag atataatgga
     6661 gaaaaagttg ttcctctttt ttataaagac gtcaagcctc taggaataag tcctagaaac
     6721 ataggacaaa agtttatgtt agaagctttt ttaacagatt ctaaaaatgc acctttagtt
     6781 atagtaaagg gacctgcagg tacagccaag actttattct ctttagctac aggacttcat
     6841 aaagttatgg aagagggaga agatggatat agaaaaattt taatctgtag acctaatgta
     6901 actatggatg aagatatagg gtttttacct ggaacagagg aagaaaaaat aatgcctttt
     6961 atgagaccca tttttgataa tttagagatt ttagtggatt ctgatgaaaa ggaaagatat
     7021 aaaaatgaaa aagaattata tgataagata aaagagctat ttgataggag aattataact
     7081 acagaagcag tagcttattt gagaggtaga tctatagtga aaaattgggt tataatagat
     7141 gaagctcaaa atttaacacc aaagcaggtg aaggcggtta taactagagt aggacaagga
     7201 acgaaactta tattagtagg tgatccagat caaatagatc aaccgttttt agactctaga
     7261 tcaaatggtt tatgttatgc atcagaaaaa atgaaaggaa gcaaactttg ttatcaggta
     7321 acattaaagg atcatgaatg tgaaagatca ccattagcct atgagggagc aaagcgatta
     7381 taattttata ctatatgtaa gtagagggcg cctcaaaatc aaatatattt tgtggtgtcc
     7441 tctatatttt atatgatata atttattaca attgcactta tgtaagttaa tgtataaata
     7501 gttttaattt ggaaaatata ttgcagttta aagggaaata aaatgaattt taggaagttt
     7561 tacaatattt cataaagctt actatttaaa aaaatttata tttagtgtac aataatgaaa
     7621 gatgtaaaat aaagagaaag gaatttttag atggaaaata aagagaaaaa gtcgaaaaat
     7681 aagaaatttt cttttaaaat atttttatat tttataattt ttgaattgtt ttttacagca
     7741 gccacagcgc cttttataat attccatggt ccttttaaaa atgttaaaaa gactatggta
     7801 ggagcagcta tgactacttt aaaacatcaa tatatagcta aaacattttt atcagatgct
     7861 aaaataaaag agatattagg tgaagattct atacaaacta taaaacaaga taagaactct
     7921 gtgttaaaat ttgaaaacaa acatgatagt acaatagaaa gatatgatat aagttatggt
     7981 aaaaagttca aaggatatat gttagtagtt catgatccat ctagggtaaa ggttggatat
     8041 agttctaagt taccagtaca aggagaactt acaagtcaga tagcaagaaa taaaagagct
     8101 gttgcagcta ttaatgcagg tggctttaca gataaatcag ctaatagcaa gtggacaggt
     8161 accggtggaa atgttgaagg ggtaataatt agtaaaggtg aagttaaata taatagtaat
     8221 aagcaaggag aatttacagg agatgtagca gctataacta aaaagggggc tttagttgta
     8281 ggtaaacata gtatacaaga attaaaagat ttaaatgtac aagaagctat aacttttgga
     8341 ccagccttag tagtaaaggg gcaaggcacc ataacttctg gagatggcgg atggggaatg
     8401 gcgcctagaa ctgctattgg acaaagagaa gacggagcta tacttatgct ggttatagat
     8461 ggtagacaag catctagttt aggagctaca ttaaaagatg tacaagatat catgttacaa
     8521 tatgatgcat atactgctac aaatttagac ggtggatctt caactacaat gtatcatgaa
     8581 ggagaagtta taaataatcc tgctaattct ttaggagaaa gatcagtacc atctattttg
     8641 tatgttgaac cttaggagga aaatatgaaa gtagtaaaaa aaataatatt atgggtaatg
     8701 atttcattaa cattacaatt tgcaggattg ttttatattg ataaatattt tttagcatca
     8761 ggaggaacac ggataaaggc taaaaaagtt acaaatacag gaacggaaaa taaagattat
     8821 gatgtaaata taccagaaaa tgtagaagag ttagatgtat cctttaatgg aaaatatatt
     8881 tcctatttta aggataataa attaaatata attagtacta aaaatggtga gaaaaagaat
     8941 attgaatttg atagtaaaaa agataaatta gaatatatat ggctttcaga tagaaataga
     9001 attatatatg cagaaaataa agaagggcaa gtattactaa attcttatga tgtagataaa
     9061 gatcaaaagg ataaaatatg tgaattcaat tttgaaagtt caagtgctaa aattgaagat
     9121 ataaaagcag caccacttat gaatttaata tatgttaagg taaatgtagg tggcaataat
     9181 aatagattat atagtgttaa tataatgaaa gaaaaagata ggatagacat aatgacagag
     9241 gcagttgggg atatgaatat aattcctcat gaagatatat taatttatga agataaaata
     9301 aataaaaaga tttttgctac acataatgaa tcatctataa atataggagg agtaacatca
     9361 ccaaaattgt tatctataga tgataacgat aatgtatata taggagaatt aaaggaagac
     9421 gaagtagtaa aaatttatta tggtaatgta aaaaataaca catctacttg gaaagcatta
     9481 gacataccta atggagctaa agtaaaagat atttatgttt caccactagg aagtgtatat
     9541 gtaaatgatg acttaaaagg tgttataaaa gagataagca caggaaaaga aacaaagtat
     9601 tctggagtta tgatgaagat gtatatagat ggagtagctt ctattagtga tggtaaatta
     9661 gtaaaaacca aatttaaata ataatataaa atttaaatgt atatgaaaat aattaaaaaa
     9721 gattgttggg tataataaat ttgaggttgt ctcaaaataa aatatatttt gagacaacct
     9781 cttttgtgta attctattga taagatgaat ttattagtat aaataataag atagatccaa
     9841 ttttttataa aacatataac aaatttggtt atttttttta caaaattgtt aaaaagtata
     9901 aattatatat aaagctattc gatattataa atataaagaa gtattaaatt aaatattaaa
     9961 tgtcatttaa tttaatattt aatagtaagg ggtgaaagat atgttaaaat ttaatgaaca
    10021 cgtactgaca accactaata acagtaataa taaggttact gtggctccag gaagttgctg
    10081 ctgctgctct tgttgttgtt gcgttagtgt tagtgtaggt ggcggttcag cttcaacagg
    10141 tggcggagca gctgctggac aaggtggaaa ttaataattt tatcttgtac aagcatcttt
    10201 cacagttcaa ttatctaata ataatttaaa cccaggtagc caggtgatta taatttaata
    10261 ttattttatc acctggctaa tatcatttaa atatttaatt tctatttaac atttaaaaat
    10321 ataaacaagg agctaaaaat gttattaaaa aacttaaaaa aacaaaaagt aaaaaagcaa
    10381 agaaatactg atataggaaa taagatgctt gttcatttta atactcagta ttctagtata
    10441 tcaccctatg tcgatagtac tgtgattaaa actccagata caataataaa ggggagcttg
    10501 tactctaaag ataacagatt tttaagtgaa gaatatcttt taaattatag aactaataat
    10561 gataatttag gttttagaat gggagtttca agtttttttc agaaggatgc tgctctcacc
    10621 tttgtaaatt tggatatgga agaagatgga caaaacgtta tagaacttcc accttctaaa
    10681 aatataagag taggtttaag tacggctata aaatctagac gtagtgtcag aggatattct
    10741 agtaaatcta tgtctttaaa tgatgtggca aatatatttt attataccca aggtatatgt
    10801 gatgaagtag aaccatataa tcttgaaggt aataaaaaga aaattaaact acgagctaat
    10861 ccatctgcag gagggttata tcctatacaa ttatatgtat atatgaagaa cataaaagac
    10921 ttaaaggatg gaatatatac atactatcct tattctcatg gtctaaaacc tattgaagta
    10981 aataaagaac ttttaaaggt agacaatttt gcagaatttg gagttctaaa tgctgaaaat
    11041 gcgaatctaa ttgtttttta tgtatataat ttcttaaaaa actcaagaaa atatggtgat
    11101 gctggatttt catatgcctt aattgagaca ggagagatgg ctcaaaatct gcaacttgtg
    11161 tctacagctt taggttatgg ggcttgtgac atagggggat atgaaaaaca atacatagaa
    11221 gaggttttag atatagatgg agtattaaaa cacgtagtac atatgactgt tgtaggctgg
    11281 gaacaggggg attaatttat gaaaaataac actatatata gattaagtaa taatttaaga
    11341 atatacgata atggtgaaaa tgaaataaga tttagaagtg gactttggaa ttacaatgaa
    11401 gcggttttag acttgagcgc tgaaacagaa aattttacaa agtcttttag aaaagttatt
    11461 gataatctaa aaaacaataa gggcatatca gtaaaggatt tagatggata tgaattaaac
    11521 aatgaagaaa aaaataattt aattagtatt atagattcct taaatgaagc tggtatgtta
    11581 tgtagtgaag atgaaaaaga taatgacttt gcaatgtcta aagtgttatt aggagatttt
    11641 agctataatc ttaataaaaa ggaagaaaat aatcaaaagc tattatttat atcagataat
    11701 gattatgcaa aacaaactgc taaaaattta tccgatggga tgaatacaaa tttagattta
    11761 tattcaaaag aaaatataga taatataatt tctaaagatt tgacatcaaa tttagatgcc
    11821 ctagaaaaaa aatctaatat agaggatata aaaaatcaat taaaagatta ttcggctata
    11881 ctaatatgca tgagtcatat taacatgaat ttatttagaa atataaatag agtatctata
    11941 gaactaaaaa aacctattat tatgtctttt attgatggac cttttataac tattttaagt
    12001 acattaccac ctaaaactgg ctgtttagag tgctttgaac aaagaatctt atcaagactt
    12061 gaagatcatg tgttatatca caaatttata gaaagtgatt ttaaacctag tgataaatct
    12121 cacaaatcca taattccctt attaaatatt atgactaaca tggtcatatc tgaaggattt
    12181 ttaataaaca attttaatac ctgcaaaatt gaaggtagag tacttagtat atttgttcca
    12241 acattagaaa tacaatctca agacctattg agagttccat tttgcccagc ttgcggaaat
    12301 atatcaaagg ctaaattgaa agaaataaac atatctacta ggaatattgt ggatggaatt
    12361 ttagaagata ttaattctta actaggaggc tttaacatga taaaattttc cccaagtttt
    12421 aataatatat tagagaattt taaatcatta gcaggaaatc aaagtggtat attagaggct
    12481 gcatgtatgc ctgtagttaa ctttaatagt gatgtgtctt taaaaagcat aacaggaaat
    12541 atgccagatt atcataaaca agtatttaat aaagatgtgt ccatgcaata tcacataatg
    12601 ggttatggat ctcattacga ggaagcttta attaaatata ccggtgaaag tatagaaaga
    12661 tattctagta ttatgggacc aacactatta aaagataaaa ttgtatatga aagttataaa
    12721 gaattaagta aaaacaataa agtcatgccc ttaaaatata tagacgtatt cacagaaaat
    12781 caaataaaga aagctaagga attaaatgtg tctatttgtg ataaaaaagt agaggaagat
    12841 gacataatag gatggattaa atgtccttca ctattaaaaa aaggtaaaga aatatatgta
    12901 ccagcaaaga tgatgtttgt aggctatgaa gaggataaaa ataaaggtga gatgactttt
    12961 ataccatcct ttagtacagg aacagcagca cataaaagtt taaagaaagc ccttttaaat
    13021 gctttagttg agtatattca aattgattct tttatgatta attggcatac aaaaggaaaa
    13081 tgttctttag tgaaaataga tgatgaaaat gtgcttaaag ttttagaaga tgtaaattta
    13141 ggagaaaagt ctccctatga aataatacct ttatatatgt ctttggagga atgtcctata
    13201 cataattttg gggttttctt aagaagaaag gataataaac ttccttattt attatttggt
    13261 atacaagggg gactggatgc ttctcatgct ttaactagag ggataatgga agcagcttca
    13321 atatcctatg gtgcatattt taatgcaatt tacaacaaag atatgttaaa taatgtaata
    13381 aaagatgatc ataaattttt agatttagat tcaaatgtgc tatattattc tcttccaaat
    13441 aaaattgaag aaaaaaataa attaatagaa gattttatag gagatgaaat tactctaagt
    13501 tctttaaata aattaaatat aaaaggtgta gatgagcaaa taaaaacttt attaaattat
    13561 ttaaaggata taagtgaata tgcagtatat ttagatttaa ctccaccaga aactagggac
    13621 aagggatggt atgttatgag agctatgatt ccggaattaa ttgaaatgtg tataccggag
    13681 tttccttttg aaaaccatcc aagaatgaaa aaatatggag gggtgattaa tgaatatccg
    13741 cacccaatgc cttaatttat taatattatt agttacattt aatccaatag tattagctca
    13801 gttattttta aataatgaaa aatcctataa tgaatcttta aaaagaagtt ttaaagcatt
    13861 agctataatt tatactataa tacttacaag tatatttatt atttccaagg aaagatttta
    13921 tataaatata gataataatt actatgggta tattattgcc gttatgtttg tacctataac
    13981 tataatttcg gaaatagctg tagggtatat tatgttaggt atttctaata aaactattcc
    14041 aaaatttaaa atatcattag tatttacaaa aactaatatt aatgtgatta tattatctgt
    14101 ttttatagga atttgtgaag aatttgcata taggcaatta tggtttaata ttttatttaa
    14161 agattttaag atgaatatag ctatagtttt aattattaca tcttttgtat atgccttaaa
    14221 ccatatattt ttaggtaaac aggtattttc ccaaaaaatg gtagcaggtc tgatttatgg
    14281 agctttattt tattttagtg gatttaatat aatagttcca ataataactc actctctaga
    14341 aaatatagct attctcttga aaggttgata aacttatgaa tttatatctt aaaattttag
    14401 tatttttatt gatgactata tacatagtaa tactttattt acctatgaat attaactata
    14461 aaaaatttaa attcacaaaa aaattatgtt taaatttaag tggagctata gggacatcac
    14521 caactaattg ttggtgttta atgaaatatg tacatttatt aattattggt gtaataccta
    14581 tagcatgctt tttttatagg gggattgtta aaaactatag tttatataca gaaacaaata
    14641 taattaagtc ttttatatta ataatattat cttttatagg aattttagaa ataagctttt
    14701 ttatgattat agttgttgtt tcatatttaa tgaaaaaaga tagtagaaaa gaaatgagca
    14761 atgtgtcatg ggtaaagttt aataaaaaat atccttttta tacaggaata cttaaaccaa
    14821 taatgtatac tgtttttgaa atattacttt attactatgt aatgttctat gtaattaatg
    14881 attatttaaa agtatcagtt atgtattcta ttttgggtat tgcaatatta tactcagtaa
    14941 gtaaactagc ttttacgaaa aataaagagc aggctttaat atatggaatt tgggcctttg
    15001 ctttaaatat tattggatct tgtataatga tttacagtaa ttctataatt cttacattta
    15061 ttctatattt attgtattca tttgtaatag cttttaaaga ataaatagag ttatttgttt
    15121 taaagggaga ttttacgcca tctaaagctt aagaaatggt tagccaagta tgcgatcact
    15181 ttttacgcca tctaaagctt tggaaatgat tggctaagta cgtagctgat ttttatattt
    15241 ccacttttaa taaaatggaa gtattagagc agtagtctat atataaaata ctataaatgc
    15301 ttattttata tggttaatat aggataagtt cataaagtat ggtatatgct gctataacat
    15361 aaatgcttac tttgcatggt tactacagaa gatatataaa ggagatgact ttatgaatat
    15421 tgtagaaata aaaaatcttg aaaagaaatt taagaataat actgctgtta ataatataaa
    15481 tttaactgtt aaagaaggac aagtctttgg attcttaggg ccaaatgggg caggaaaaag
    15541 tactactata aatatgattt gtggactttt aactcctact aagggtgaga tatttatttt
    15601 aggtaagaaa atggacaata aagctaagga tttaaaaaat aatattggta ttgttccgca
    15661 agacatagct atatatgagg atctaactgc ctatgaaaat gtagctttct ttggaggact
    15721 ttatggtgtg agaggacaag aactaaaaga aagagcaaag gaaactttag aatttgttgg
    15781 cttattagat agagcaaagg attttcctta taaattttcc ggcggtatga aacgtagatt
    15841 aaatattgcc tgtgctctag tacatcaacc taaacttata ataatggacg agcctaccgt
    15901 gggaattgat cctcaatcaa gaaatcatat cttagaatct ataaaaaaac taaatgaaag
    15961 aggctgtaca ataatataca caagtcatta tatagaagaa gtagagcagt tatgtacaga
    16021 tatagccatt attgataaag gaactattat agctaagggc aaaaaagatg agttagtaga
    16081 aaaatactct gatttaaata tggttgtaat taatattaaa gattcaacta aagtaaatat
    16141 aaaagcatta aaatctatag aaggtgtagt ggaggttaat attaaagaaa atactattga
    16201 aattacaaat aagtcctctg ataatttgga tgatataata atgtactttt taaacaataa
    16261 aataaaaata aaaaatatag agaataaaca tagtgattta gaaactatat tccttaaatt
    16321 aactggcaaa aaattaagag attagaggtg aactctatga agatattaaa tatattaaaa
    16381 aaagaaatac ttgaaaattt cagagataaa aaagctatgt ttttaatgac gttgtttcct
    16441 atgcttttaa ttaccatatt aggaacggtt ttttcaggaa actttgcatc tacaattaat
    16501 attccagaga ttaatgttat gtattctata aataaggatg taaaaataga taaaaacttt
    16561 aaagatttta ctaaagagat tcaaaaaaac atgaaggtta attttaaaga aactaaagaa
    16621 gaaaaagatg ctttagaaaa aataagtaat ggaaaagctg atgtgtatat aaaaattcca
    16681 aatgataaaa aaatatatat ttatgaaaat aatgtgagag catttaattc tcaattagtt
    16741 agtacgttgt tagatacttt tgtggataaa gtaaatatga caaaggaagt atcctcaaaa
    16801 aatccaatgg cattgtctaa aataaaagta gataattcac ctaattttgt aaatacaaaa
    16861 acaatagatg gcaaaaattc gccaagagga atagattatt atgctgttac tatgcttact
    16921 atgactattt tatatggaac tgcagttggg gctatgagta ttgccagtga aataaaaaga
    16981 aggacttaca aaagattaat ttgtagtaat acatcacctt taaaaatatt attttcaaaa
    17041 atattagctt cttttttagt aatagccttt caaagctttc taatatattt atttagtaaa
    17101 tatattttag gaacaaattg ggggaataat aaattagctt tgatttctgt ggtagcatct
    17161 ttaatattta tggcagtatc tgcaggagta tgtatagcta atactataaa aaatgaaggg
    17221 gttatgtcta tcattatata tatgtttgta cctgttttaa cttttcttgg tggaggttat
    17281 atacctttag atacaatagg cagtaaaatg ttaaattctg catcaaatat atcaccactt
    17341 aaatggagca acgatgccat atttaagatt atttttggta acgatctgag tatatttgga
    17401 acaactatgt taatcaacct aggggcagga gttttattct tattaattgc tatattattc
    17461 ccaagaaagg atgtggtata aaatgaaaca aatattttta ttaaccaaaa gtattctaaa
    17521 aagaactttt agaaaaaaat ctaatataat aacttttata ttacttcctt tattagctgt
    17581 atttatagct ttatttttaa atgcttcagg aaattcttat agcaaaatag gagtagtaga
    17641 tttaaatgaa tcctatttat ctaaagacat gataaagtca atagatgcca agaaaaattt
    17701 tgttgtagtt aaaatttcaa agaataatat gaataaatta ttactggata aaagagtaga
    17761 ttgtgtagta gttattccta aggattttaa taaagatata atagatggaa attttaaaaa
    17821 attggatata atatctgtta gaggagaaga tattacttct tggattaaaa attatttaaa
    17881 ttattatata gatactctta ataatataag tgtggcatct aataaaaatg aaaaagattt
    17941 taaagctata tatgatggat ataaaaagca agatttgaag cttaattata aagctatagg
    18001 agacaaaact aaaactaaat ctgtaacaaa gcaaagcata ggattattac ttgtatttat
    18061 gctaatagct tctagtacag cctcatcttt tatattaaag gataaatata ataaaacata
    18121 ctatagaata ttttgttcta atactagtaa aagcaaatat ataatagcta atgtaatagc
    18181 taactttgtg atttttttaa tacagatatt tgtgattcta tttatgtcca tatatgttct
    18241 gaaacttaat ttttatatag atacaagtat aatgtttata atattgtgtt cttttggatt
    18301 tgtatccatt ggctttggaa taatcattgc agccttttcc aaaagtctta atcaatcatc
    18361 ctatttatct aatatactaa taacacctac ttgtatgcta tcaggatgtt tttggccttt
    18421 agacatgatg ccaagtttca tgcaaaaatt agctaatata tttcctcaaa catgggtgct
    18481 taaaactata gattctcttc agcaaggaaa aagttttaat gaggttattt catatcttgg
    18541 tatagtaatt ttatttgcat tagctttctt tgtagtagga atactaaaat taactaagga
    18601 tgaaaactta aaaagtattt tttaagatat aaaaaataaa tgtatatata tgaatatcta
    18661 tttattttat attaatattt atttaattgt tgtatttatt taaatttgct ataattgttt
    18721 tgaagtttca attttaggag aggatgagtt ttttggactt aaactataga atactttcga
    18781 aaatactaat aataccagct atattagtag gccttacagt acatgaattt gctcatgcct
    18841 atgtagcaga caaattagga gataaaactc ctaaatttca aggaagatta acattaaatc
    18901 ccttttcaca tatagacatt ataggtttta taatgatatt attaattgga tttggatggg
    18961 caaagccagt acaaattaat ccaagtgcat taaaaagagg atataaagat gagataaaag
    19021 tttctgtagc aggggtaact gcaaatgtaa ttacagcatt tttatttgca ttattaacag
    19081 ctttcttgtt aaagttaaat ttagtgaact ttggagatat aacttcctta ggtggtataa
    19141 taggtttaat attgaactat atagttagaa taaattgtat gctagcaata tttaatttaa
    19201 tgcctatacc aggacttgat ggctttgaca tattgagaga tttatggcct aagacttttt
    19261 ataaaatatc tgatgtaatt tatagatatc aaatgattat tctattgata tttgtggtaa
    19321 ctcctatttc atcattttta gtaggaattc caactaattt tttacattat tcttttatga
    19381 aaatagctat gactatattt tagaatttta attttttaat aaaagtataa aaattagata
    19441 tttatcgtat taaaattaaa ctagaaaaag gtgatttttg tattgtacag aggtcatctt
    19501 tttttacata tttatattta gggagattat ttttatttaa tggatatttt acaaagttta
    19561 cataaacaga gttcttggtt ttagagggag tttttacttc tactaaagct taggaaatgg
    19621 ttatcaaggg acatagccgc tctttacttc cactttgaag aagatgggag tattagagag
    19681 gatagtcatc ggataaaaca atttaagcat aagtagttat ggagctgatt tgttgtttaa
    19741 atataaaaaa gtctaggaac atgtcttaaa aaatatattc ctagacttta atagtttact
    19801 actataaaat ttataatttt gtacattata aattatttat atactaattt tgctttatta
    19861 attttttaat ttattttgta gttttatcat aaacaacatc agctttagta gatacttcct
    19921 caagtttttc ttttaagcta tctatattct gttgtatatc agctaaatca tattttgaaa
    19981 cattatagtg taaataaaga ttttcaaaag atttaactat atcaacaaaa tcctttccag
    20041 tattaatgaa tttattgaac ttattactat tttttgcatt ttcaaactta gatatatcta
    20101 tttttatagt atttattaca tcttcttctt tctcaaactg tccaatagtt acattgtaag
    20161 gagaaattct ttctagaaaa tatttatttt ttttatccaa gtgatacatg tattttatct
    20221 tcacagagtc tattgtaaat tctacataac atactattcc tgtgattcta tgaatcttag
    20281 ctcccatttg ttctagtaaa aaagttaaca ttgaattttt tactttcata taattgtcca
    20341 tttaaaagcc ccctcatgaa ttaagtgagt tatcttttgt ttatattata tcattaagcg
    20401 agtatcaata tccacaattt tcaaaatatt ataaaataat tttgaaatca tctcaaaatt
    20461 atttcaaaaa aaacattaaa aggtaagcgg tacatattat tattgatact aacattacag
    20521 gaaacccaag tttaaagtag tctttaaaag aaattttata accacttttt tctgctatgc
    20581 caattactac taggttggca gaagctccga tcatagttcc atttccacca agacaagcac
    20641 ctaaagataa tgcccaccaa agtggaacta tatccatacc acccatggtg cccatagctt
    20701 ttattaaagg tatcatagta gctacaaaag gaatattatc tataaatgca gaggcaatag
    20761 cagatatcca aagcacaaat attcccgtca taactaggtt gccttttgtt agtgacattg
    20821 ttttctgtgc taagacttcc atgatgccaa catcttctaa aactccagtc attataaata
    20881 aacctatgaa aaagaatata gtaccccatt ctgtttcttg tagtatttca tctggctcta
    20941 ctttgcttat agctaataat atagcagaac cagctatggc gatagttgca gattcaaaac
    21001 ctaaataact atgagttaag aatcctatta aagttaaaaa tagtactgtt aagcattttt
    21061 tcataagaga catatcacga atagctttac tttcatctaa agccataatt tttttcttat
    21121 cttcttcaga agttttcata gaatttttat ataattgtct tattcctaat aatgtaactg
    21181 tgagtattat tattattaca ggagctaagt tcttaacaaa atctaaaaag cttaatccag
    21241 cagcacttcc tatcattaag tttggtggat ctcctattaa agtagcagtg cctcctatgt
    21301 tagatgcaaa tatttcacac attaaaaaag gaatcggatc tatttctaat gttttagtta
    21361 taactaaggt tacaggtact attaaaagca cggtagtaac gttgtctaat actccagata
    21421 aaacagcagt tattacagaa aatagtatta atattttaat aggattccct ttggaaaatt
    21481 tagctgcttt tatagctata tattcaaaga cacctgttct tttagttata tttactataa
    21541 tcatcattcc aactaatagg cctatagtat taaaatcaat ttttaagaaa gccttttctt
    21601 gggtgattaa ttttaatata agcataatag cagctccgcc tagcgaagca acaaccctgt
    21661 ttactttttc tgaaataatt aatgcataaa ctattataaa tataattgct ggaagcatca
    21721 tgttaaaatt attaaatatt ttaatcatcc ccctataaaa aattttagta cgtacctcta
    21781 gattttaata cgaatttgga aataaataaa ccccttttca attaattata tatttaacaa
    21841 agatttctta ttttacggcc ttttctaatt cattaaataa ggatttaaca cctttccacc
    21901 aattaatatc ttcagcatat gtattgttca cccatttaaa aggatcttgt cctttaggca
    21961 tagtttttaa taaattaaat acggttcttc ctgctattct agaagaatct ttaatatcag
    22021 aattatattc ttcccaacta tgaaaaacgt tgaatggatt atttcctatt tttttagcag
    22081 atttgttgct tttaggtaca aaaccttgtt cttgtccagt tattgcaaat aatattaaag
    22141 gatttatatc aaattcctct gcagatgata ttatagatga gaaataaggt tcatctgcta
    22201 ataaagagtt tttggtatat aaatatttct tcagtttttc attatttaaa gttttatatt
    22261 taacatattg aggtagatgc ttatttttat cgagaatatt atttttttta gttttaacat
    22321 ttttattttc ataaacaata atatttttac tattagtttt aatagaagta tccatattaa
    22381 ataaatatat agatattgaa gaaataaata atatagttaa tgcaaaagta atagagttat
    22441 tataaagttt aaatatatta tttttgtata aaaaatctat attgaatttt ttagtaatac
    22501 ttttagtatt atatttatta tttgttatat ttgctgtatt ctgtttgata ttaataaaat
    22561 tattattaga ttctgtatgg gcgttttgta gataaataga atcaaccttt ttaattttta
    22621 tatagggttg ttcatctgcg attttggtgc tagaatcttt agaactagaa ctagaactag
    22681 aactagaact agaactagaa ctagaactag aactagaact agaactagaa ctagaactag
    22741 ttttaatttc accatttttt tcatgatttt ttagtaaact atttgtatag aaataattta
    22801 ctaaagattc ttcatcagtt ttatttttta tattaatgtt aatccaattt aataatattt
    22861 ttatgttttc ttttttaaaa tctacatagt ctatataaga ataaaagata tcccataaat
    22921 aaatggaatc tttattattt aaaaatgtat tttttaaaat agcatttttt aaatctttat
    22981 gtattgattt tggaaagaaa tctattttac tttcaataat attatgaata gtagaagata
    23041 ccatataagc ttttcttttg ctatcttcat ttttatattt aatatttata aatttcttaa
    23101 tcttttcaat atcattttta cttataattt tagtggcttt taattcttct aaaaaattac
    23161 tcataatata tgttcctata taatccttcc aatgataatt ctactaaata gtataattat
    23221 cgccatataa tgttgttact taaattatta gagaaaataa taaaaacata aatttacaga
    23281 atgtgaggat aggcattagt ataatcgtca caggttaaaa taattagagt atggtgtagt
    23341 tgttttttaa aatataatta aatatagatt actaataata ataggtgtta tgatataata
    23401 tttcagtagt agattaaaaa gatatctgga ggttaaaaaa tgagacttag aaaaaaatgg
    23461 tgggcaagac cagagataga agctagtgat aaatttgcag aggaacctaa agaattaaga
    23521 ggaaaatgga ataaggaatt taataataat aatgatatac atttagaatt aggttgtgga
    23581 agaggaggat ttatatcaca attagtagaa aaaaataaag atataaatta tgtaggaata
    23641 gatttaaagg atgaagttat agtttatgct ataagaaaag ttaaagaaaa ggaagaagaa
    23701 gttaaaagag agtttaaaaa tataaaattt gttacaatga atataatggg aatag
//
