LOCUS       NZ_CP079740.1          20894 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP079740.1 Paraclostridium bifermentans strain DSM 14991 plasmid
            unnamed3, complete sequence.
ACCESSION   NZ_CP079740
VERSION     NZ_CP079740.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:54:38
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 5406
            Orig. end    :: 26300
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..20894
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[15406:16300](-)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10894)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..20894
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..20894
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(728..847)
                     /locus_tag="ctg4_6"
                     /transl_table=11
                     /translation="MTLLLIIGIIIYIVKNKRNNEDVFLENDKIIDVNYREVD"
     CDS             complement(892..987)
                     /locus_tag="ctg4_7"
                     /transl_table=11
                     /translation="MTTIIGSLMIVPFILAVGAGLLKNELEIANQ"
     CDS             complement(1049..1144)
                     /locus_tag="ctg4_8"
                     /transl_table=11
                     /translation="MIVICSVVMAPFILAVGAGLVSNELDAANQQ"
     CDS             complement(1204..1299)
                     /locus_tag="ctg4_9"
                     /transl_table=11
                     /translation="MAIVIGSLMIVPFILAVGAGIVSNELEMANQ"
     CDS             complement(1388..1477)
                     /locus_tag="ctg4_10"
                     /transl_table=11
                     /translation="MTIIGVLMIVPFVLAVGAGLVSSELEVAN"
     CDS             complement(1671..2498)
                     /locus_tag="ctg4_11"
                     /transl_table=11
                     /translation="MKKILFVTDLYYKANGRNYYQEDLFITSKLVDKFNLVICNPKDMN
                     KFNDDFDLTIFRNAGPVANFPKEYNNFREKIKRNNLKTYNSFDGKGDMNGKDYLIELTN
                     LGYPVISTVDSINNINKLPKVDKYVIKPKDGADSIGMEFVTKEELYEKVLKDDFNTLIQ
                     PAINFEYEVSFYYIDKEFQYALYAPDKRKRWELKEYDATTSDLEFAMKFVEWNNIDHGI
                     QRIDACRDEEGNLLLVELEDLNPYLSVLELSNQLQNKFIESLKKSIENVLNGN"
     CDS             complement(2935..4251)
                     /locus_tag="ctg4_12"
                     /transl_table=11
                     /translation="MLNKVGIDTRDIFKVSIVFMNFIIFFCTLDVVSIRKISNIKILQY
                     IGILICILVVVSVSNIFRNFRILLYIIFGIIYYNLVYDEVLVKCLIVTILFWISVMVVE
                     TTSIGAIAAINNISDLNYIINQKRYVIQAIILSKVLLLIEFVLLRYFKLALEFKPKDMA
                     LIGLSISYNILSLLLVFGYNFLNSILSKLNIVFLILITMLLMLSTISLLVVIARIRRSD
                     RLKLETELINERTQMNYKNYENIYEVHSSLRHVYHDLKNHMMCIKNYNSKEDIIKYIDN
                     LSFEIRMFDSISHTGNETLDIILSQKIHECNKYNIKFESNINFSKLGFISNIDVCSIFG
                     NALDNSIEACKLIDCCIDRKIEVKVTYIKQFCIIKIINTKQNKINLTKKGIQTSKYNKY
                     EHGIGLASIKRTVDKYDGEVAVNFSETEFILKIMIPIKS"
     PFAM_domain     complement(2947..3261)
                     /aSDomain="HATPase_c_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14501.8"
                     /description="GHKL domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_12_0001"
                     /evalue="8.20E-26"
                     /label="ctg4_12"
                     /locus_tag="ctg4_12"
                     /protein_end="435"
                     /protein_start="330"
                     /score="89.9"
                     /tool="antismash"
                     /translation="SNIDVCSIFGNALDNSIEACKLIDCCIDRKIEVKVTYIKQFCIIK
                     IINTKQNKINLTKKGIQTSKYNKYEHGIGLASIKRTVDKYDGEVAVNFSETEFILKIMI
                     P"
     CDS             complement(4245..4955)
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 66.2; E-value: 5.3e-20)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg4_13"
                     /transl_table=11
                     /translation="MVVLGICDDEKHYRSIIRKYLEEILQSNVQSYEIHEFTSGEELLE
                     NYPNNLDILILDIQMDGIDGMNTARRIRTFDSKVEIIFMTSYSEFMQEGYEVRAYRYLL
                     KPIDFDKLNKHITPCVKEVKRSNSNYLTINTKNYIDRINIDSILYIETQRPNLLIYTRK
                     KIHSVRMSMRKIEGILEEYSFYRCHNSFLVNLKEIESMDGEYIFIDHIKIPVSRYRTKG
                     LKLAITNTLGDIVC"
     PFAM_domain     complement(4278..4535)
                     /aSDomain="LytTR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04397.17"
                     /description="LytTr DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_13_0003"
                     /evalue="4.00E-18"
                     /label="ctg4_13"
                     /locus_tag="ctg4_13"
                     /protein_end="226"
                     /protein_start="140"
                     /score="65.6"
                     /tool="antismash"
                     /translation="RINIDSILYIETQRPNLLIYTRKKIHSVRMSMRKIEGILEEYSFY
                     RCHNSFLVNLKEIESMDGEYIFIDHIKIPVSRYRTKGLKLA"
     PFAM_domain     complement(4608..4940)
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_13_0002"
                     /evalue="5.70E-22"
                     /label="ctg4_13"
                     /locus_tag="ctg4_13"
                     /protein_end="116"
                     /protein_start="5"
                     /score="78.1"
                     /tool="antismash"
                     /translation="ICDDEKHYRSIIRKYLEEILQSNVQSYEIHEFTSGEELLENYPNN
                     LDILILDIQMDGIDGMNTARRIRTFDSKVEIIFMTSYSEFMQEGYEVRAYRYLLKPIDF
                     DKLNKHI"
     CDS             5467..6027
                     /locus_tag="ctg4_14"
                     /transl_table=11
                     /translation="LENKKDWSYDKKINYIITLQEKGLSRKEIAEKMSYTRVDTLDRFM
                     KKYGYQKFDGKFILTIDNIYPKHNSNSLISSNYDPFTVNSNQLFNNYEIQEKLLNIVKN
                     YDKIISLINNFESKEDNCPIDVIEVKTGLQINFNKSEVIKTTIRLDKDIWNDFSDLCKN
                     KYSHLNKHDIISKAFLEFIDKYN"
     CDS             6794..6970
                     /locus_tag="ctg4_15"
                     /transl_table=11
                     /translation="MFLLNFIGINYSNWLWIDYALFVFAIFIILSVIFYFGNGFYIVFK
                     QKKASKKQNTKSN"
     CDS             7150..7998
                     /gene_functions="other (smcogs) SMCOG1157:hypothetical
                     protein (Score: 96.8; E-value: 2.6e-29)"
                     /gene_kind="other"
                     /locus_tag="ctg4_16"
                     /transl_table=11
                     /translation="VAKNQTILTHMSFKGGSSKTCLNLNFIHQFCTNYPHKKVLFIDAD
                     PQSNASVFLLGEEVIQSNIYTLKDGLESNIEIDKLIMKSPLSKFQNLDIIASNIDMVTL
                     ELVLNTKAGKEYTLLNYLTDDKNIDVFSEYDLVLFDLNPAISVLNTNVFICCTDIVPII
                     NYGCYSTLTGYDLLLKTYGDIKKALRIDKDDIRKPVITKFEKQENNKIKMWLECATEKG
                     ILGNTFKQTMRKSVHYENSILYNESISEYVKVKERKIKTDIGNEISDLINEYIEEGLIV
                     I"
     PFAM_domain     7168..7713
                     /aSDomain="AAA_31"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13614.8"
                     /description="AAA domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_16_0004"
                     /evalue="1.20E-22"
                     /label="ctg4_16"
                     /locus_tag="ctg4_16"
                     /protein_end="188"
                     /protein_start="6"
                     /score="80.7"
                     /tool="antismash"
                     /translation="ILTHMSFKGGSSKTCLNLNFIHQFCTNYPHKKVLFIDADPQSNAS
                     VFLLGEEVIQSNIYTLKDGLESNIEIDKLIMKSPLSKFQNLDIIASNIDMVTLELVLNT
                     KAGKEYTLLNYLTDDKNIDVFSEYDLVLFDLNPAISVLNTNVFICCTDIVPIINYGCYS
                     TLTGYDLLLKTYGDIKKAL"
     CDS             8071..8424
                     /locus_tag="ctg4_17"
                     /transl_table=11
                     /translation="MNIENPMLNKKSSLLNIKQKVDEKSTGQEFIENKNTDINVFDLIN
                     KPKLKEEKVMIGIKLKKEIADKVKSFSYENNMTVSQVLEDIVCKMFDSVELNVDALTAY
                     EEKYKKKSKKNKK"
     CDS             complement(8479..9111)
                     /locus_tag="ctg4_18"
                     /transl_table=11
                     /translation="MKYISKIPDTDINLNKDMLSTGWKMLKEPRNLVTATLISLPISII
                     NIYLCIFFIKLINKDLLTIINSIFYDGKFVFTIKPVYIVYIYMYIFLHEVIHLVCIPNF
                     ANSKSTFISVKLWGGFVYTEEIISRNRYLIVTIMPFIILSFVMPIIMTLLGVNPMIILI
                     LEIVNAAGASVDVLSFILLFFQAPRNSKIKNNGIKTFYKSSKVSNLD"
     PFAM_domain     complement(8545..8853)
                     /aSDomain="DUF3267"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF11667.10"
                     /description="Putative zincin peptidase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_18_0005"
                     /evalue="7.70E-18"
                     /label="ctg4_18"
                     /locus_tag="ctg4_18"
                     /protein_end="189"
                     /protein_start="86"
                     /score="64.9"
                     /tool="antismash"
                     /translation="YMYIFLHEVIHLVCIPNFANSKSTFISVKLWGGFVYTEEIISRNR
                     YLIVTIMPFIILSFVMPIIMTLLGVNPMIILILEIVNAAGASVDVLSFILLFFQAPRN"
     CDS             complement(9155..9727)
                     /locus_tag="ctg4_19"
                     /transl_table=11
                     /translation="MDKKRVVKLVLFIAFITICISAYSIYSKGKETIDTKYGLAYGDPN
                     AKIKLVEYMSFQCIDCYELHENIGDTLRDKIKNGEIYYVVKHVDFEKFKYDDVIFNRID
                     NLDKIETVDYIMDNYKTWSKMKNVKDVEEFFKLGAIKKDRVEMQKHILSERDDLGIDFI
                     PTFYLNGEKHVGSFTEKEFNKMISDVK"
     PFAM_domain     complement(9167..9622)
                     /aSDomain="Thioredoxin_4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13462.8"
                     /description="Thioredoxin"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_19_0006"
                     /evalue="1.30E-18"
                     /label="ctg4_19"
                     /locus_tag="ctg4_19"
                     /protein_end="187"
                     /protein_start="35"
                     /score="67.8"
                     /tool="antismash"
                     /translation="KYGLAYGDPNAKIKLVEYMSFQCIDCYELHENIGDTLRDKIKNGE
                     IYYVVKHVDFEKFKYDDVIFNRIDNLDKIETVDYIMDNYKTWSKMKNVKDVEEFFKLGA
                     IKKDRVEMQKHILSERDDLGIDFIPTFYLNGEKHVGSFTEKEFNKMIS"
     CDS             complement(9720..10004)
                     /locus_tag="ctg4_20"
                     /transl_table=11
                     /translation="MKKTLGIVSAAYFILIPFSIVFYLLYSLISNKSVNLFNGGVVLDI
                     AQSSFKLNISSNLVLIYIVLYIVLIGLVFIVSRTKFCKNFYEKGKRANG"
     CDS             complement(10001..10894)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Thurincin_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_21"
                     /sec_met_domain="PF05402 (E-value: 6.4e-17, bitscore: 53.6,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1.7e-11,
                     bitscore: 35.9, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 5.5e-12, bitscore:
                     37.3, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="Thurincin_rSAM_RRE (E-value: 7.4e-12,
                     bitscore: 37.1, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLFTFLIEKIKELLKIKTVFIIPNSVDLNENLIFDKDLNKSITL
                     NGVAYEILKLVNGKNTIDDIVIALLKKYNVKKTVLERDVINILSNLQDKNLVESKVIGN
                     KIVVLFLNISIFQYVYKKRYSVSESKFGSLTLLIYVVTKKLFVMWMITFITIYLFKHNL
                     VSEFNEKINYAIDCYLVFILSIIGGFVMHEWIHIAVSKIQNQEFRGYILARRFTVSIVK
                     VNTESSLLSILLGPLIPSVLGIIIIVISIKIQSVMIFTLGIGFAINVINLLPFTQDGKG
                     ILRKILMKKLMKGAIK"
     PFAM_domain     complement(10604..10795)
                     /aSDomain="PqqD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05402.14"
                     /description="Coenzyme PQQ synthesis protein D (PqqD)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_21_0007"
                     /evalue="1.20E-13"
                     /label="ctg4_21"
                     /locus_tag="ctg4_21"
                     /protein_end="97"
                     /protein_start="33"
                     /score="51.2"
                     /tool="antismash"
                     /translation="IFDKDLNKSITLNGVAYEILKLVNGKNTIDDIVIALLKKYNVKKT
                     VLERDVINILSNLQDKNLV"
     CDS             complement(10940..12403)
                     /locus_tag="ctg4_22"
                     /transl_table=11
                     /translation="MRLEKSFLILTTMLKGVKNSLYNKIKKYFVFISIVVPFFILLGAI
                     ISYKIFSPMINAIISGNKSMLFSFISSSMLNVTLITFVIYIILINSDNDSSNYSKIIKW
                     LPLTKKEKICAQTIQELFFIIITNLCYVTFFHLPSFIGSKVNIKIIIIYLISVILQSLL
                     IYFLLNIIYLLIIRLLYFISHKKFIRELASIILGINTFIYLVSKINLDSLLVKSNSYKV
                     SIVNILLPVIDMCLGYGYFNYKDAKVGLTLSGIILILGILITIIFAGIELDNRNLMIFK
                     YIPKYKGKMLWIVIKEVKHIVRSETNISNFFVLICIIISVGFLDPNTIDKTIANLILSS
                     FCSIFALSSFGEDRNFTIYSNIVPISSKLISYGKLIGNLIIGILLYTILFFIVFTYLGI
                     NIELFKSGLMYTAMGVIVIYTYGIVIPVREKEPFSNIIVFLSFAAICILISIISLTFSG
                     AYIYQLILISVVAITLMIPKLYKLNSKLD"
     CDS             complement(12360..13115)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 144.1; E-value:
                     9.1e-44)"
                     /gene_kind="transport"
                     /locus_tag="ctg4_23"
                     /transl_table=11
                     /translation="MLYVDNLTKTYNNKIVAIKNLSFSLNKNKVLGLVGPNGSGKTTTI
                     NLILGTIKRDTGKILYENYKNDSLEFKQKVGYIPDDLILPESLTGREYIDFILSVYSIK
                     KSDKLKKLIQLYNMQDFLDILIKEYSHGMKKKIQIIVAFSLESEVIIIDEPFRGLDIES
                     IIITKQLFKSFISSGSILLCSHDLNLIEELSDEVIMLYKGNTVAKGTSHRLKEEFECED
                     LEEVFMKVAIGEDRKNEIGEIISNFNNNA"
     PFAM_domain     complement(12648..13061)
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_23_0008"
                     /evalue="2.60E-24"
                     /label="ctg4_23"
                     /locus_tag="ctg4_23"
                     /protein_end="156"
                     /protein_start="18"
                     /score="86.4"
                     /tool="antismash"
                     /translation="KNLSFSLNKNKVLGLVGPNGSGKTTTINLILGTIKRDTGKILYEN
                     YKNDSLEFKQKVGYIPDDLILPESLTGREYIDFILSVYSIKKSDKLKKLIQLYNMQDFL
                     DILIKEYSHGMKKKIQIIVAFSLESEVIIIDEPF"
     CDS             complement(13238..13456)
                     /locus_tag="ctg4_24"
                     /transl_table=11
                     /translation="MELIQYNAPVIECDNFEITEEQAWFLVFVAVLLALGATVVLGAAI
                     WCLVQGKGSFTGGVKWENGLNVNIECK"
     CDS             14079..14222
                     /locus_tag="ctg4_25"
                     /transl_table=11
                     /translation="MVLISLFQILSILLLINVFVIIFISIFKFLKSNNQIDIEINKLKD
                     KE"
     CDS             14316..14525
                     /locus_tag="ctg4_26"
                     /transl_table=11
                     /translation="MEKKQYVCPKCSNTSYESDQFQATGGNFAKIFDIQNKKFITISCT
                     KCGYTELYKSNTSDGWNILDFLIG"
     PFAM_domain     14334..14522
                     /aSDomain="zinc_ribbon_13"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09855.11"
                     /description="Nucleic-acid-binding protein containing
                     Zn-ribbon domain (DUF2082)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_26_0009"
                     /evalue="1.50E-31"
                     /label="ctg4_26"
                     /locus_tag="ctg4_26"
                     /protein_end="69"
                     /protein_start="6"
                     /score="108.4"
                     /tool="antismash"
                     /translation="VCPKCSNTSYESDQFQATGGNFAKIFDIQNKKFITISCTKCGYTE
                     LYKSNTSDGWNILDFLIG"
     CDS             15273..16379
                     /locus_tag="ctg4_27"
                     /transl_table=11
                     /translation="MSNLTDIENPKILMKNNVLIQSKYSLTLNENRIFLLILYKLQKNY
                     NGSMHCDIHYDEFKEIIKRTNDRTVKKISSYLEGLMNKSIFFIEKKRNDKLIWGQYNFI
                     SGYQFDEETQIFRIESPKKIYTLLDQYLKTGYTPANLAILFSLKNYNAQRLYDLIRVWS
                     GTKQTINYKIEDIKMYLMLEDSYPQYSNFKRRVILPAIKELNESGFFEIDIKENKSGRK
                     VESIDFIVKDLDKRKYFSKDDVIDQIGESNIYEQSSVPEPFEESKINLKLEKSILNREF
                     FVPDETVFTKGTLRSFKMDFENIDFKNDYMKKAFDDAVMITLDKDDVETIKAVSYKFFK
                     GTLDNKILEYKKEYEEDLKHKEEMDLFW"
     PFAM_domain     15303..15959
                     /aSDomain="Rep_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01051.23"
                     /description="Initiator Replication protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_27_0010"
                     /evalue="9.70E-33"
                     /label="ctg4_27"
                     /locus_tag="ctg4_27"
                     /protein_end="229"
                     /protein_start="10"
                     /score="113.9"
                     /tool="antismash"
                     /translation="KILMKNNVLIQSKYSLTLNENRIFLLILYKLQKNYNGSMHCDIHY
                     DEFKEIIKRTNDRTVKKISSYLEGLMNKSIFFIEKKRNDKLIWGQYNFISGYQFDEETQ
                     IFRIESPKKIYTLLDQYLKTGYTPANLAILFSLKNYNAQRLYDLIRVWSGTKQTINYKI
                     EDIKMYLMLEDSYPQYSNFKRRVILPAIKELNESGFFEIDIKENKSGRKVESIDFI"
     CDS             complement(16686..16907)
                     /locus_tag="ctg4_28"
                     /transl_table=11
                     /translation="MAIIVNLDVMMAKRKMSSTELSEKLGITMANLSILKNNKAKAVRF
                     TTLNSICNILECQPGDILEYVDDTEDVK"
     PFAM_domain     complement(16704..16892)
                     /aSDomain="HTH_26"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13443.8"
                     /description="Cro/C1-type HTH DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_28_0011"
                     /evalue="2.50E-24"
                     /label="ctg4_28"
                     /locus_tag="ctg4_28"
                     /protein_end="68"
                     /protein_start="5"
                     /score="85.6"
                     /tool="antismash"
                     /translation="NLDVMMAKRKMSSTELSEKLGITMANLSILKNNKAKAVRFTTLNS
                     ICNILECQPGDILEYVDD"
     CDS             complement(16917..17405)
                     /locus_tag="ctg4_29"
                     /transl_table=11
                     /translation="MEKNISSKILNNIVLLGITLTICLLLFLPLGFTAFFKSNFGIVGS
                     NIPIILSVGVYVCAVPYLIALISLKKLCSLIANKDPFSRQIPYHLKTISICAFSEILIF
                     NVVQLFLCYFFNVYFYALNIIPAILVSFISLAIGFLSLVLGRLYTMAIEIKEENDKTI"
     PFAM_domain     complement(16920..17267)
                     /aSDomain="DUF2975"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF11188.10"
                     /description="Protein of unknown function (DUF2975)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_29_0012"
                     /evalue="3.10E-17"
                     /label="ctg4_29"
                     /locus_tag="ctg4_29"
                     /protein_end="162"
                     /protein_start="46"
                     /score="62.8"
                     /tool="antismash"
                     /translation="IPIILSVGVYVCAVPYLIALISLKKLCSLIANKDPFSRQIPYHLK
                     TISICAFSEILIFNVVQLFLCYFFNVYFYALNIIPAILVSFISLAIGFLSLVLGRLYTM
                     AIEIKEENDKTI"
     CDS             complement(17423..17899)
                     /locus_tag="ctg4_30"
                     /transl_table=11
                     /translation="MNKNFSSTILNNIVSIGIFITLILFLLIPLSFNYFFKNTLGLVGG
                     NISLFVSTGVYICIIPYLIALITLKKLCSLIYNKNPFSRETTYLLKTISLCAFSEFFVF
                     NIVQLYLCNLFDIYLYSINVIPTVLISFISLFVGLFSLVLCNINSKILKIKNIK"
     PFAM_domain     complement(17435..17746)
                     /aSDomain="DUF2975"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF11188.10"
                     /description="Protein of unknown function (DUF2975)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_30_0013"
                     /evalue="5.90E-11"
                     /label="ctg4_30"
                     /locus_tag="ctg4_30"
                     /protein_end="155"
                     /protein_start="51"
                     /score="42.4"
                     /tool="antismash"
                     /translation="STGVYICIIPYLIALITLKKLCSLIYNKNPFSRETTYLLKTISLC
                     AFSEFFVFNIVQLYLCNLFDIYLYSINVIPTVLISFISLFVGLFSLVLCNINSKILKIK
                     "
     CDS             complement(17927..18142)
                     /locus_tag="ctg4_31"
                     /transl_table=11
                     /translation="MKKNLLYSIPFLIAIGCLVIFNIIGSEVATDGTLIEPFFLIPTFW
                     LFSFIGILALIFKFMLFLFKKKHISQ"
     PFAM_domain     complement(17975..18127)
                     /aSDomain="DUF3955"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13127.8"
                     /description="Protein of unknown function (DUF3955)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_31_0014"
                     /evalue="1.10E-12"
                     /label="ctg4_31"
                     /locus_tag="ctg4_31"
                     /protein_end="56"
                     /protein_start="5"
                     /score="47.8"
                     /tool="antismash"
                     /translation="LYSIPFLIAIGCLVIFNIIGSEVATDGTLIEPFFLIPTFWLFSFI
                     GILALI"
     CDS             complement(18452..18820)
                     /locus_tag="ctg4_32"
                     /transl_table=11
                     /translation="MISLSNKKQVEKLQFEKTRLEIKVVKLEDEVLKLKSEVKKQEDLI
                     NEWRRYYKESVQEISKLKNQLKEFNPNLKPRSKKISQNDIDKIKELFNMKKYTYREISN
                     ISNWSICTISKVINGYYD"
     CDS             19086..19448
                     /locus_tag="ctg4_33"
                     /transl_table=11
                     /translation="MKEKQKEECSKIIKEILFTESNISKSFDELLNKVIVNEFDSISHY
                     NNKLNLIKDILGYYNERTYLVQKILSDYLNLIEPSQEFKDFKFKSENTHKNYINTDLEK
                     LKVDDDYEIIDRCKSD"
     CDS             complement(19508..19765)
                     /locus_tag="ctg4_34"
                     /transl_table=11
                     /translation="MLTNLVLILLSITALSLNHTEDKDANKYVFYGTFLIINIVLLFGV
                     RNLISYIIIALLSILCIFAFIKISFKNNKLSQQKSRIKKD"
     CDS             complement(19973..20434)
                     /gene_functions="regulatory (smcogs)
                     SMCOG1284:transcriptional regulator, MarR family (Score:
                     64.4; E-value: 1.6e-19)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg4_35"
                     /transl_table=11
                     /translation="MDNNDIKLKKAIEVLQSFYSVIKETSDFTKKNAHELGMTIQQLSI
                     LNALATNSNLTLKNLTEVMSMSLSKSSVSLIVDKLVEQDIVERKSSTLDRRQIILNLTE
                     KGIQLYQQSQSNAYAYKAMLLALNGIDSKDIDLLLTVHDHIIENIKALK"
     PFAM_domain     complement(20144..20329)
                     /aSDomain="MarR_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12802.9"
                     /description="MarR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_35_0015"
                     /evalue="7.40E-10"
                     /label="ctg4_35"
                     /locus_tag="ctg4_35"
                     /protein_end="97"
                     /protein_start="35"
                     /score="38.8"
                     /tool="antismash"
                     /translation="LGMTIQQLSILNALATNSNLTLKNLTEVMSMSLSKSSVSLIVDKL
                     VEQDIVERKSSTLDRRQ"
ORIGIN
        1 aggtaaaaaa atttggtaaa acttggttaa taacagaaca atctatgata aaacactttg
       61 gtgttgatga atttaatttg tatattggta aaattacttt agacgattta gatgaagtga
      121 aacagaaaaa aattaaaaag aaaatggata aaaagtctga gttaaatgaa cttaaaatag
      181 gtatttaaaa agtataaata taatcttttt cattatacaa tttttttcat aatgaaaaag
      241 attatattta tttttttact cattaaactt taaggtattg taaaaagaaa tagttatatt
      301 tgaatcgact tgaattatga tttatctgaa tctagattaa tagatttgaa atataataaa
      361 tttgtgttag atttgtatat atggtcatat aaattttatt aaaaaatcta atttaaagta
      421 ttaatttttc tgtttgctag acgtatatct aatataccta aacaattata ctttttatat
      481 aatttaaata gaatcaatta aaaccctata tttttattga tagagttata taaaacctaa
      541 ttatgttttg ttttaatttt ttatacttaa tacaagtaga attacatttt accctcattg
      601 tattaaatta ttaagatttg tcctaattag ccttctacac actaacctat ataaacggtg
      661 gcgtatgaag gttaatttgc ttatatacta tttttttgta atattgaatt atataataag
      721 acttgttcta gtcaacttct ctataattaa catctattat tttatcattt tctaaaaaaa
      781 catcttcatt atttcttttg tttttaacaa tatatattat aattcctatt attaataata
      841 atgtcatagt aactcctcca tttttattat gtcttaaatt ttcaatttat attattggtt
      901 tgctatttct aattcatttt ttaataaacc ggctcctact gctagtataa atggaactat
      961 cattaaactc cctattattg ttgtcatctt attgttcctc cctcattttg tatcctataa
     1021 tcttatatta tctaactgct ttaccattct attgttggtt agctgcatct agttcattac
     1081 ttactagtcc tgcgcctact gctaatataa acggtgccat cactacactg catattacta
     1141 tcatatataa tttctccttc gcctttttat atttattcta tacactcaaa ttaattttaa
     1201 gttttattga tttgccattt ctagttcatt gcttactatc cctgcgccta ctgctaatat
     1261 gaatggaact atcattaaac tccctattac tattgccatc ttattattcc tcccttgttt
     1321 tttatcttat attcttatat tacatcttta atcttaaaca tttcttaaat attttaaacg
     1381 tctattgtta gttagctact tctaattcac tacttactag ccctgctcct actgctagta
     1441 cgaatggaac tatcattaaa actcctatta ttgtcatata taattcctcc tttgttttat
     1501 ttgttaactc tattatacat ttacatactt aaaatagcct ttcaccaacc ttaaagattt
     1561 cttacatttt tgatatgtta aatttattat tataataagt ctaaaaacaa caaaaataga
     1621 tatataaaag gagcatcatt aatgatgctc cttttatata tctatttttg ttaattaccg
     1681 tttaaaacat tttcaattga tttttttagt gattcaataa atttattttg aagttgattt
     1741 gataattcta atacagatag atacgggttt aaatcttcta attcaacaag taaaagattg
     1801 ccttcttcat ctctgcatgc atcaatcctt tgaataccat gatctatatt attccattca
     1861 acaaacttca tcgcaaactc taagtcagat gtagttgcat catattcttt taattcccat
     1921 ctctttcttt tatccggggc ataaagagca tattgaaact ctttatctat atagtaaaaa
     1981 gacacttcat attcaaagtt tatcgctggc tgaattaatg tattaaaatc atcctttaga
     2041 actttttcat ataattcttc ttttgttaca aattccattc ctattgaatc tgccccatct
     2101 tttggcttta taacatattt atctacttta ggtagtttat taatattatt aattgaatct
     2161 acagtgctga ttacaggata tcctaaatta gttaattcaa tcaaataatc cttgccattc
     2221 atatctccct ttccatcaaa tgagttatat gtctttaaat tatttctttt tattttttct
     2281 ctaaaattat tatactcttt aggaaaattt gcaacaggac ctgcatttct aaatatagtt
     2341 aagtcaaaat catcattaaa cttattcata tcttttggat tgcaaataac taggttaaat
     2401 ttatctacta atttagatgt tataaaaaga tcttcttgat agtagtttct tccgttcgct
     2461 ttataatata aatctgttac gaataatatt tttttcataa tagcgcactc ctttttaata
     2521 cattctatca gattgaaaaa tatttacaat aaatttttaa aattcagaat tattatttca
     2581 taaataatta aatacttctt ctattttcat ttttgaccaa aattcttgtt tattttaagt
     2641 ttaaaaagtc aaaataattc caattttttt gactttttta aatttaatga tgtatatatt
     2701 atagtgtttt caatatatgc atcattaaat ccatttatat tttttatatt cctcttaatt
     2761 tttaactttt aataaataat ccacttataa aataatatat tgttgcattt gaaaaattaa
     2821 tacattaaga gttaaactat ttttttaatg ggtaatataa acataagcac cttctaattt
     2881 aacataataa aaaagcacat aaaatataga gtctatattt tatgtgcttt tttattatga
     2941 ctttataggt atcattatct tcaaaataaa ttcagtctca gaaaagttca cagcaacttc
     3001 tccatcatac ttatctacag ttctttttat acttgctaat cctataccat gttcatattt
     3061 attatattta cttgtttgta ttcccttttt tgtaaggtta attttatttt gtttagtatt
     3121 tataattttt attatgcaaa actgtttaat ataggttact tttacctcta tttttctatc
     3181 aatacaacaa tctattaatt tacatgcctc tattgagtta tctaacgcat ttccaaatat
     3241 ggaacataca tctatattac ttataaaccc tagttttgag aaatttatat tcgattcaaa
     3301 cttaatgttg tatttattac actcatgtat cttttggctt aaaattatat ctaaagtctc
     3361 attccctgta tgagaaatac tatcgaacat tcttatttcg aaacttaagt tatctatgta
     3421 tttaataata tcttctttac tattataatt ttttatacac atcatatgat tctttaaatc
     3481 atgatataca tgccttaagc tactatggac ctcatatata ttttcataat ttttgtaatt
     3541 catttgagtc ctttcattta taagctctgt ttcaagctta agtctatcag atcttctaat
     3601 tctagctata actactagta atgaaatagt tgataacatt aaaagcattg taattaatat
     3661 taaaaataca atatttaatt tgcttaatat actatttaaa aaattatatc caaaaactaa
     3721 taataaactt aatatattat aacttatcga aagacctata agagccatat cttttggttt
     3781 aaactctaat gccaatttaa agtatcttaa taatacaaat tctattaaaa gtaatacttt
     3841 agatagtata attgcttgaa ttacatacct tttttgattt attatgtaat ttagatctga
     3901 tatattgtta attgctgcta tagccccaat tgatgtagtc tctacaacca ttacacttat
     3961 ccaaaacaat atagtcacta ttagacattt cactaaaact tcatcatata ctaggttata
     4021 gtatatgatt ccaaatatta tatataataa aattctaaaa tttctaaata tatttgatac
     4081 acttaccact actaaaatac aaattaaaat gcctatatac tgcaaaatct ttatattact
     4141 aatctttcta atacttacta catctagtgt gcaaaaaaat attataaaat tcataaatac
     4201 tattgagact ttaaatatgt ctctagtgtc tatacctact ttatttaaca tactatatcc
     4261 cctagagtat tggttatagc tagttttaat cctttcgttc tatacctact tactggtatt
     4321 tttatatgat ctataaatat gtattctcca tccattgatt caatttcttt taaattaact
     4381 aagaaactat tgtgacatct ataaaaactg tattcttcta atattccttc aatcttcctc
     4441 atactcatcc ttacactatg aatctttttc cttgtataaa ttaataaatt cggtctttga
     4501 gtttcaatat acaatataga atctatgttt attctatcta tatagttctt tgtattaatt
     4561 gttaaatagt tactattgct tctttttact tcttttacac aaggtgttat atgtttattt
     4621 aatttatcga aatctatagg ttttaatagg tatctataag ctcttacttc atatccttct
     4681 tgcataaatt cagaatagga agtcataaat ataatttcta ctttactatc aaatgttcta
     4741 atccttctag ctgtattcat accatcgatg ccatccattt gtatatctaa aatcaagata
     4801 tctaaattat tagggtaatt ctctagtagt tcttctccag atgtaaattc atgtatttcg
     4861 taactctgta catttgattg taatatttct tctaaatatt ttctaataat tgacctataa
     4921 tgcttttcat catcgcatat gccaagtaca accatttaaa aatcccccta acatattttt
     4981 tgtcattaca taatatctta tatcggtacc tttttctagt ttttaaagat aattatctca
     5041 ttttagttat cttttaattg ttaaatttaa ttaacttaac acaaaaagaa gtattcaatt
     5101 tgaatacttc ttttgttaag ttaattaaat ttatgtttat aaccctaaaa cacaactatt
     5161 aaaaatctaa atataccctt ttctatttag attttaatta acttttatat acttttatcg
     5221 acactatgag tttgaatttg aattgagata cttagttcat acttttatgt atgtacttat
     5281 ttacaaacta tataaaaagt atacgtctta aaaaaacttt gttcaatgct ttgttgcata
     5341 ctagacctta acttatgcat tttagatatt ttttaattaa aagctaaatt tcaactaaat
     5401 acgcaatttt taaatagtat aataatatgg aggactagtg tcctccatat tgttgggggt
     5461 ggtaacttgg aaaataagaa agattggagc tatgataaaa aaataaatta tataattact
     5521 ctacaggaaa aagggctatc aagaaaagaa attgctgaaa aaatgagtta tacaagagtt
     5581 gatactttag atagattcat gaaaaaatat ggatatcaaa aatttgatgg taaattcatt
     5641 ttaaccatag ataatatata tcctaaacat aactcaaact cacttatttc aagcaattat
     5701 gacccattta cagtaaattc aaatcagcta tttaataatt atgaaattca agaaaaacta
     5761 ttaaatatag ttaaaaatta cgataagata attagtctta taaataactt tgaatctaag
     5821 gaggacaatt gtcctataga tgtaatcgag gtaaagactg gccttcaaat aaatttcaat
     5881 aaatccgaag ttataaaaac tacaatcaga ttagataaag atatatggaa tgatttttct
     5941 gatttatgta aaaataaata ttctcattta aataaacatg acattataag taaagcattt
     6001 ttagagttta tagataaata taattaattt tattaatatc taacttttaa atgtaacact
     6061 aactcaaacc taatataatc aattggtgac tgcatacata tattagttga taaaataagg
     6121 aggacaaacg tcctccttat tttatttata agtctatatt tatatatttc gcttatcata
     6181 tccctttata attattttaa catgacgata attatattta gaatcactat ttatttaata
     6241 taacaatgag gtgaccccta tgagaatcga gtacaatgac aataaatcta tttttaaatt
     6301 caacttttta aaaaacaaag atttgaaaaa gcaaagtaac ttttatttta tttttggagt
     6361 aataatttat ataatttata ccattaatac tttaaaatct tatactataa tagatggaag
     6421 ttttgaggtg tttttcatta gcttattttt taattttata ttaatgattt taacttttat
     6481 aatttttcat ttagtctatt ttacaaaata taatagtgaa tttataccta caaatactac
     6541 tttaattatt acaataatta cttttctgcc atctgtagta ttattgtttt tatctatttg
     6601 aaaattcaca tttataaaat aatcagcata tatttaaaag taattaaata tacatttaat
     6661 agtgtattta ataattatct ctaattttga aagagacttg ttatcacgaa ataagtctct
     6721 tttttctata cttaaataac attttcaaca ttaaattaat aaattaaaaa aataaaaatg
     6781 aggtgttagt gtaatgtttt tactaaactt tataggcata aactattcaa actggctctg
     6841 gattgattat gctttatttg tatttgctat atttataata ttaagtgtaa ttttctattt
     6901 tggtaatggt ttctatattg ttttcaaaca gaaaaaggct tctaaaaaac aaaataccaa
     6961 atctaattaa tttaaaactg aattatataa tagtattaat attttatttt taaagagcta
     7021 tatttttagc tctttatttt taatctttat aaatagatta aattagtatt taaaaataat
     7081 ttaattaatg ataaaatata tattaaacta ctattaaatg tatatttaat ataaaaagga
     7141 gtaataaaag tggctaaaaa tcaaacaatt ttaacacata tgagctttaa gggtggtagt
     7201 tccaaaacat gtttaaatct aaattttata catcaatttt gtacaaacta tccccataaa
     7261 aaagtattgt ttatagatgc tgatcctcaa tcaaatgcat cagtattttt attaggagaa
     7321 gaagtaattc aatccaatat atatactttg aaagatgggt tagaaagcaa tattgaaata
     7381 gataagttaa ttatgaaatc tccgctaagt aaatttcaaa atttagatat tatagcaagt
     7441 aatatagata tggttactct tgaattagtt cttaatacaa aagccggtaa ggaatatact
     7501 ttattgaatt acttaactga cgataagaat atagatgttt tttcagaata tgatttagta
     7561 ttatttgatt taaatcctgc tatatctgtt ttaaatacaa atgtatttat atgttgtaca
     7621 gatattgtgc ctataataaa ctacggatgt tatagcactc taacaggtta tgatttgtta
     7681 ttaaaaacct atggagatat aaagaaagct cttagaatag ataaagatga tataagaaaa
     7741 ccagttatca ctaaatttga aaaacaagaa aacaataaaa taaaaatgtg gttagagtgt
     7801 gctacagaaa aaggaatttt aggaaataca tttaaacaaa ctatgagaaa gtctgttcac
     7861 tatgaaaact caatattata taacgaatcg attagtgagt atgtgaaagt taaagaaaga
     7921 aaaataaaaa ctgatatagg aaatgaaatt tccgacttaa taaatgaata catagaagaa
     7981 ggtttaatag ttatttaata aaaattttat aattattaaa aatacattta atcaatatta
     8041 aatatttatt aaatattagg agagaaagct atgaatattg aaaatccaat gttaaataaa
     8101 aaaagcagtt tattaaacat aaaacaaaaa gtagatgaaa aatcaacggg ccaagaattt
     8161 attgagaata aaaatactga tattaatgta tttgacttaa taaataaacc aaaattaaaa
     8221 gaagaaaaag ttatgattgg aattaaatta aaaaaggaaa tcgctgataa ggttaaatct
     8281 ttttcttatg aaaataatat gactgtttct caagtcttag aagatatcgt ctgtaaaatg
     8341 tttgactcag ttgaacttaa tgtagatgcc ttaactgcat atgaagagaa gtataaaaaa
     8401 aaatcaaaga aaaataaaaa ataattaata aatgtataaa aaagggagga caattgtcct
     8461 ccctttttta tacatttatt aatctaaatt agatacttta ctactcttgt agaaagtttt
     8521 tattccattg ttttttatct tgctatttct tggagcttga aaaaacaata gtataaaaga
     8581 taatacatct actgatgctc ctgcagcatt aacaatttcc aaaattaaaa taatcatagg
     8641 gtttacccct aataaggtca ttataattgg cattacaaat gacaatatta taaatggcat
     8701 tatagttact atcaagtatc tatttctact aattatttct tctgtataaa caaaaccacc
     8761 ccatagtttt actgaaataa atgttgattt agagtttgca aagtttggaa tacatactaa
     8821 atgaataact tcatgtaaaa atatatacat atatatgtat actatatata caggcttaat
     8881 tgtaaaaaca aattttccat cataaaaaat agagtttata attgtcaata agtctttatt
     8941 tataagctta ataaaaaata tacataaata aatatttata attgatatag gtaatgatat
     9001 tagagttgct gtcactaagt ttcgaggttc ttttaacatt ttccaaccag tactaagcat
     9061 gtccttattt aaattaatat ctgtatctgg tattttactt atatacttca taaaaatttc
     9121 ctttcattta catgtatgcg tattctatat atacttattt tacatcactt atcattttat
     9181 tgaactcttt ttctgtaaat gatccaacat gcttttcacc atttaaataa aatgtaggta
     9241 taaaatctat cccaagatca tctctttcag acagaatatg tttttgcatc tcaactctat
     9301 cttttttaat agcacctagt ttaaaaaact cttcaacatc tttcacgttt ttcattttac
     9361 tccatgtttt ataattatcc attatataat ctaccgtttc tattttatct aagttatcaa
     9421 ttctgttgaa tataacatca tcatacttaa acttttcaaa atcaacatgc tttactacat
     9481 aatatatttc accattttta attttatctc ttaatgtatc tcctatattt tcatgtaact
     9541 catagcagtc tatacattga aaactcatgt attctaccaa ttttattttg gcattagggt
     9601 ctccatatgc tagtccatac tttgtatcta tagtttcttt acctttagag tatattgaat
     9661 atgctgatat acagattgta ataaaagcaa taaataaaac taatttaact actcttttct
     9721 tatccatttg ccctctttcc tttttcatag aaatttttac aaaacttcgt tcttgaaact
     9781 atgaatacta atccaataag tactatatat aaaactatgt atatcaaaac taagtttgaa
     9841 cttatgttta atttgaaact actttgtgct atatctagta caactccacc attaaataaa
     9901 tttacgcttt tgttacttat caaggaatat aacaagtaaa aaactatact aaacggtata
     9961 agtataaaat atgcagcaga tacaattcct aatgtttttt tcattttata gctcccttca
    10021 ttagtttctt cattagaatt tttctaagta ttcctttccc atcttgtgta aaaggtaata
    10081 gatttattac attaattgca aatcctattc ctagagtaaa tatcattaca ctttgtattt
    10141 ttattgaaat tactattatt atgattccta aaacgcttgg aatcaatggt cctagtaaaa
    10201 tagataataa actagattct gtatttacct taactatgct tacagtaaat cttcttgcta
    10261 atatgtatcc acgaaattcc tgattttgaa ttttactaac agctatatga atccattcat
    10321 gcataacaaa tccacctata attgaaagta taaaaaccaa gtagcagtca atggcataat
    10381 ttatcttctc attaaactca gatactaaat tatgtttaaa taagtaaata gttataaaag
    10441 taatcatcca cattacaaac aacttttttg ttactacata aatcaaaaga gtcaaagatc
    10501 caaatttaga ttcagaaaca gagtatcttt tcttatacac atattgaaat atacttatgt
    10561 ttaaaaataa aactactatt ttattcccta ttaccttact ttcaactaag tttttatctt
    10621 gtaaattgct taatatattt attacatctc tttctaatac agtctttttt acattatact
    10681 ttttgagtag cgctataact atgtcatcta tagtgttttt gccattaacc aattttaaaa
    10741 tttcataagc aaccccattt agtgtaatgc ttttatttaa atccttatca aaaattaaat
    10801 tttcatttaa atctacgcta ttaggaataa taaaaactgt ttttattttt aataattctt
    10861 ttatcttttc aattaaaaat gtaaataggt tcatctaatc tctcctttat aaattaaaat
    10921 gtattattta aatataaatt taatctaact tagaatttaa cttataaagc tttggtatca
    10981 tcagcgttat agctactaca gatattaaaa taagttgata tatatatgca ccactaaatg
    11041 ttagtgatat tatagaaatc aaaatacata ttgccgcaaa agataaaaat acaattatat
    11101 ttgaaaatgg ctctttttct ctaactggaa ttacaatacc atatgtgtaa atcactataa
    11161 cccccattgc agtatacatt aatccacttt taaataattc tatatttata cctaaatatg
    11221 taaatacgat gaaaaatagt atcgtatata gcaatattcc aataataaga ttccctatta
    11281 gtttcccata agaaattaac ttactagaaa taggaactat attagagtaa atagtgaaat
    11341 ttctatcttc accaaatgaa cttagtgcga atattgaaca aaaacttgat aaaattaaat
    11401 tagcaattgt tttgtctata gtgtttggat ccaaaaaccc tacagatata attatgcata
    11461 ttaatacaaa gaaatttgaa atattagtct cacttcgtac aatatgttta acttctttta
    11521 ttacaatcca taacatttta cctttgtatt ttggtatata tttaaaaatc attaaatttc
    11581 tattatcaag ttcaattcca gcaaatataa tcgttattaa tattcctaaa atcaaaatta
    11641 ttccacttaa agtcaaacca acttttgcat ctttatagtt aaaatatcca tatcccaaac
    11701 acatatctat aacgggtaat aaaatattta ctattgatac cttatatgag ttacttttaa
    11761 ctaaaagact atctaggtta attttactaa ctaaataaat aaacgtattt atacctaaaa
    11821 taattgaggc taattctctg ataaattttt tatgtgatat aaagtacagt aatctaatta
    11881 ttaatagata aataatattt aataagaaat atatcaataa tgattgcaaa attacagata
    11941 ttaaatatat aataataatt tttatattaa ccttggatcc gataaatgat ggtaggtgaa
    12001 aaaatgttac atagcataga ttggtaataa ttataaaaaa taattcttga attgtttgtg
    12061 cacatatctt ttctttcttt gtaagaggta accattttat tattttgcta taattactgc
    12121 tatcattgtc tgagttaatt agtattatgt atataacaaa agtaattaaa gttacattta
    12181 acatacttga ggaaataaat gaaaaaagca tacttttatt tccgctaata atagcattaa
    12241 tcataggcga aaatatctta tacgatataa tagctcctaa aagaataaaa aatgggacta
    12301 caatagatat aaaaacaaag tattttttaa ttttattata taaactattt ttaactccct
    12361 taagcattgt tgttaaaatt agaaatgatt tctccaatct cattttttct gtcctcccct
    12421 atagcaactt tcataaaaac ttcttctaag tcttcacatt caaattcttc ttttaaacga
    12481 tgacttgtgc cctttgctac agtattacct ttataaagca ttattacctc atccgataat
    12541 tcctcaatta aatttaaatc atgtgagcat aataatatac ttcctgagct tataaagctc
    12601 ttaaaaagct gttttgttat tataattgac tctatatcta accccctgaa aggttcatca
    12661 ataattatta cctcgctttc taatgagaaa gcaactatta tctgaatttt tttcttcatt
    12721 ccatgtgaat attcttttat caaaatatct aaaaagtctt gcatattata cagttgaatt
    12781 aattttttta atttatcact tttctttata gagtatactg ataaaataaa atctatatat
    12841 tctctcccag tcaaagattc cggtagtatc aagtcatctg ggatgtatcc aactttctgt
    12901 ttaaattcta gactatcatt tttataattt tcatataata tcttacctgt atctcttttg
    12961 atagtcccta agattaaatt aattgttgta gtctttccag atccattagg gcctacaagc
    13021 cctaaaactt tatttttatt taaagaaaaa ctgagatttt ttatagcaac aattttattg
    13081 ttataagttt ttgtcaagtt atctacataa agcatagttt acacattcct cccagtactt
    13141 aaatcaattt atagacttag gtgtcctaaa tttaaatctt tatcttttgt tatagtttta
    13201 aattttttag tataatttta ataaattaaa gtcctatcta tttacactct atgttaacgt
    13261 taagtccatt ttcccactta actccaccag taaaacttcc tttaccttga actaaacacc
    13321 aaattgcagc tcctaaaaca acagtagctc ctaatgctaa aagtactgct acgaaaacta
    13381 aaaaccatgc ttgttcctca gttatttcaa aattatcaca ctctattaca ggtgcattgt
    13441 attgtattaa ttccatttcc caatctcctc ctctaattta aatagaacac ctaagtcaaa
    13501 agacattgtt agatatttga caaccttgcc tttgtataaa ttgttgcata tcaaaaaatc
    13561 gtttgcaata ttcagttcga ataatgtcaa aatttttata taatttaata aattgaaata
    13621 agtaaacgtg tttagttaat ctactatata tactgtgtac gaatattgga attacataat
    13681 attcactttc atgatgtaag gatattttgg aaataaattt ttatattttg tatattaaaa
    13741 atcaaataag tctatttttg ttgaaatttg cttaatttta tatttttttg tcattttctt
    13801 ccctattagc taactttttc tcttttctaa aacttaaagt tcggatgaaa tttaataata
    13861 tttatcctaa gtattaaaat aaatattgtt gtaagtagtt aattctaacc tatatgttaa
    13921 aacttttaaa aatactttat atttaaatct taatctaaat atatgctcat tttaatccaa
    13981 ttttatttta attcactcta tttaaattga tttattttac ttaatctgta taataattat
    14041 caatctgagt taactacaaa tatgtaaagg agttcataat ggttttaata tccttattcc
    14101 aaatcttaag cattctgtta ttaattaatg tatttgtaat tatatttata tcaattttta
    14161 agtttttaaa atctaataat cagattgata ttgaaatcaa taaattaaaa gataaggaat
    14221 aatataaagt tttatattgt aactaatttt aattagtttt tttttattta ttatagtaaa
    14281 attttactca aatcaatatt aggaggattt aagttatgga gaaaaaacaa tatgtttgcc
    14341 ctaaatgttc aaatacatct tatgaaagtg atcaatttca agctacaggt ggaaactttg
    14401 caaaaatatt tgatatccaa aataaaaaat ttataactat aagctgtact aaatgtggat
    14461 acactgaact ttataaaagt aatacatcag atggatggaa tattttagat tttcttatag
    14521 gttaatatat caaattcaaa taaaaaaagg atattattta ctaatatcct ttttttattt
    14581 gaatttgata ttaaatttct cattttattt tataaaaatt acagtttttt cgatctttat
    14641 cttccgtttt tagctaaatt ttctaaattc ccatatattt acccattttg atgtgcaaaa
    14701 actttctcat aggcgctgag aggtttttat ctatatgtaa actttattct ttgatagtta
    14761 atatttcttg aaaaagattt ttacgtaaag ttaaaaaata tattactaat atttataatt
    14821 aaattaatca tctaaatagc aaaataaata tgtcatattg ataatatatt ttgatttaaa
    14881 tagattagat tagaacagaa aagtaccttt actagtcttt actattattt aaaatagtat
    14941 ttaatagtat ttatagtatt taagtagcag tgaaaacctt gaaatcactt atactgaagc
    15001 gattaaaagt gtcaacttga tagttaaaag tgtcaacttg atagttaaaa gtgtcacttt
    15061 gatagttttt atatgtcaac ttgatagtta aaagtgtcaa cttgatagtt aaaagtgtca
    15121 ctttgatagc attaaaagtg tcactttgat agcatattaa tataacaaaa agttaatact
    15181 gttaaaatac agtgtcaaaa ttgaaaaagt gacactttta aattatacat atgatatact
    15241 agttttagta gttaatagaa ttggggggta ttatgagtaa tttaactgat atagaaaatc
    15301 caaaaatact tatgaagaac aatgtgctaa tacaatctaa atatagctta acattgaatg
    15361 aaaatagaat atttttgtta atactttata aacttcaaaa aaactataat ggatcaatgc
    15421 attgtgatat tcattatgat gaatttaaag aaataataaa aagaacgaat gatagaactg
    15481 tgaaaaaaat aagtagctat ttagaaggtc ttatgaacaa aagtatattt ttcattgaaa
    15541 aaaagagaaa tgataaattg atttggggac aatacaattt tatatcagga taccagtttg
    15601 atgaagaaac tcagattttt agaatcgaaa gccccaaaaa aatttatact ctattagacc
    15661 aatacttaaa gacaggatat actcctgcaa acttagctat actatttagt ttgaagaatt
    15721 ataatgctca aagattatat gatttaataa gagtttggtc aggaactaaa caaactataa
    15781 attataaaat tgaggatata aagatgtatt taatgctaga agatagttat cctcaatatt
    15841 caaattttaa aagacgtgta attttaccag caataaaaga actaaatgaa agtgggtttt
    15901 ttgaaataga tataaaagaa aacaaatcag gaagaaaagt tgaatcaata gattttatag
    15961 taaaagactt agacaagaga aagtacttct ctaaagatga tgtaattgat caaattgggg
    16021 agtctaatat ttatgaacaa tcaagtgtac ctgaaccatt tgaagaaagt aaaataaatt
    16081 taaaattaga aaaatctatt ttaaatagag aattttttgt tccagatgaa acagttttta
    16141 caaaaggaac cttaagaagt tttaaaatgg atttcgaaaa tatagacttt aaaaatgatt
    16201 atatgaaaaa agcatttgat gatgctgtta tgataactct agataaagac gatgttgaaa
    16261 ctataaaagc cgtatcatat aaattcttta agggaacctt agataataaa attttggagt
    16321 acaagaaaga gtatgaagaa gatttaaagc ataaagaaga aatggattta ttttggtagt
    16381 cttaaaatat gtcaacttga taatcacact aaaagtttaa ataataaaaa atatatatat
    16441 taaacatttc aagtatagta gaaatagtag acaaataaat caaaatgtgt catattgata
    16501 atttaaaaaa attattatgt atcaaaactt caagtgaaat gctaagtgat tgaaaatgct
    16561 aatgtttaac tgttttaaat tataatgatt taaaaaaatt tttatataaa agcaacacat
    16621 tgataattag aattaaaaag ctactgtttt tttattaaaa acagtagctt tttgattaac
    16681 tatagctatt taacatcttc agtatcatca acatattcca aaatatctcc aggttgacat
    16741 tccaatatgt tacaaatact atttaaagtt gtgaatctaa cagctttagc tttattattt
    16801 ttcaaaatgg aaagattagc catagtgatt ccgagctttt ctgaaagctc agtagaactc
    16861 atttttctct ttgccatcat tacatctaaa ttaactataa tcgccataat atctccttat
    16921 atagtcttat cattttcttc ttttatttca attgccatag tgtataacct acctagcact
    16981 aaacttaaaa atcctatagc taaagaaata aatgaaacta aaatagctgg aattatgtta
    17041 agtgcataaa agtaaacatt aaagaagtag cataaaaata attgtaccac attaaatatc
    17101 aaaatttcac taaaagcaca tattgatatg gtttttagat gataaggaat ttgccttgaa
    17161 aaaggatctt tgttagcaat taaactgcat aattttttca atgatatcaa tgctattaaa
    17221 taaggtacag cacacacata aactcctaca gataaaataa taggaatatt cgagccaact
    17281 attccaaagt tacttttaaa aaaggctgta aacccaaggg gcaagaataa aagcaaacat
    17341 attgttaatg ttattcctag taaaacaata ttatttaaaa tttttgaact aatgtttttt
    17401 tccataatta ttacctcgtt ttttatttta tgttttttat ttttagtatt tttgaattaa
    17461 tattgcataa aactaaacta aaaagtccta caaataaaga aataaatgaa attaaaactg
    17521 ttggaattac atttattgaa tataaataaa tatcaaataa attacacaaa tataattgta
    17581 ctatattaaa tacaaaaaat tcactaaaag cacataatga tattgttttt aataaataag
    17641 tagtttccct tgaaaatgga tttttattat atattaaact acataatttt ttaagtgtaa
    17701 ttaatgctat taaataagga attatgcata tataaactcc ggttgaaaca aataaagata
    17761 tattcccacc cactaatccc aaagtatttt taaaaaaata gttgaacgat aaaggtataa
    17821 gtaaaaataa tattagagtt ataaatatac ctattgagac aatattgttt aaaattgttg
    17881 agctaaaatt tttattcatt atttcatatc ctattttaaa atatatctat tggctaatat
    17941 gttttttctt aaatagaaat agcataaatt taaaaattaa ggctaaaatt cctatgaaag
    18001 aaaataacca gaatgtaggt attaagaaaa atggttctat aagagttcca tctgtagcaa
    18061 cttcagatcc tataatattg aaaattacta agcatcctat tgctattaaa aatggtattg
    18121 aatataataa attttttttc attgtagact ctcctttaaa tttgctttaa ttaaattata
    18181 acatataatt ataataaatc aatataaaat tattgttttt cgataaaaaa gtattctttc
    18241 ggaatattta gatgaaaatt taataatgaa attgtataaa atattttata gattttaatt
    18301 agatgcttat ggtaattaag gttaaatatt tacaatcata aataaaaaag gatctaaaag
    18361 attatatagt aaaaatcttt tagatccttg gtaaaatgta taaaaataat attgattaat
    18421 tgatagattt aacttatata ttctaaagta attaatcata ataaccatta attactttag
    18481 aaatagtaca tatactccaa ttagaaatat tacttatttc tcgataggta tattttttca
    18541 tattaaataa ttcttttatt ttgtctatat cattttgaga tatttttttg cttctaggtt
    18601 ttaaatttgg attaaattcc ttaagttgat tttttaactt ggatatttct tgtacggatt
    18661 ctttataata tcttcgccat tcattgataa gatcttcttg ctttttgact tcagatttta
    18721 acttaagaac ttcatcttct aattttacaa ctttaatttc aagcctagtt ttttcaaatt
    18781 gaagtttttc aacttgcttt ttatttgata aacttatcat aaaaaaacct ccgttaatga
    18841 cctacttaac attaactgta gtatattata caaaaaaatc aactattttt tgagaaaact
    18901 aaaattatct aagttaacta gctaaataac gaataattcc tagttgaaac aagtatttaa
    18961 aaatattaaa ggtttaaata actaagtgta aactaaaaag ttcaattgaa tacattatta
    19021 atataatttt taagatgtta actttattaa tataacaaaa ttatgcagaa aggatagatt
    19081 gacacatgaa agagaaacag aaagaagaat gttctaagat aataaaggaa attttattta
    19141 cagagtctaa tataagcaaa tcttttgacg agttattaaa taaggttata gtaaatgaat
    19201 ttgattctat atcacactac aataataaac taaatttaat aaaagatatt ttaggttatt
    19261 ataatgaaag aacttatcta gttcaaaaaa ttttgagtga ctatttaaac ttaattgaac
    19321 cttctcagga gtttaaagat tttaaattta aaagtgaaaa tacgcataaa aactatataa
    19381 atactgattt agaaaagtta aaagttgatg atgattatga aataatagat agatgcaaat
    19441 cagattaatg attgctaaat taattatctc agcaaaaatc aagaataaaa aaagattaaa
    19501 tatacattta atcttttttt attcttgatt tttgctgaga taatttgtta tttttaaatg
    19561 agatttttat aaatgcaaat atacacaaaa tagaaagcaa agcaattatt atataagaaa
    19621 ttaaatttct tacaccaaat aataaaacta tattgataat tagaaatgtt ccataaaaaa
    19681 catacttgtt tgcatcttta tcttcggtgt gatttaagct taatgccgtt atagacaata
    19741 agattaaaac taaatttgtt agcatagtta tcacctacga atttattttt tgtttaataa
    19801 accgttttaa tatgtattaa taataattta tacccgaata tattttttta tatcataaaa
    19861 cttataatcg ggtatgatac ttaacattta attatattaa aaaagttata ccagtaaaga
    19921 tagtgtaaag caaattccgc aaatcacctt taacctttaa ataatgatat aactatttta
    19981 aagcctttat attttcaatt atatggtcat gtactgtaag taataaatct atatctttag
    20041 aatctattcc attaagagct aataacattg ctttataggc ataggcgtta ctttgtgatt
    20101 gttggtaaag ctgaatacct ttttcagtaa gatttagtat aatttgtctt cgatctaatg
    20161 ttgatgattt tcgttcaact atatcttgct caactaattt atcaactatt aagcttacag
    20221 aacttttcga aagagacatt gacattacct cagtaagatt ttttagcgtt aagtttgaat
    20281 ttgtagctag tgcatttaaa atagataatt gctgaatagt catccctaac tcatgagcat
    20341 ttttctttgt aaaatcacta gtttctttta taaccgaata aaatgattgc aatacttcaa
    20401 ttgctttttt taatttaatg tcattattat ccattattat cctccaaaaa tattttacaa
    20461 ttaaattgtt taataataaa ataatttaac cataaaaatt tattgatgtc aattttatat
    20521 actacaatta tagtatataa aaatccatca gagtatagaa ataaagactc tgatggattt
    20581 aaaagatgat atacacataa aataaatttt attttaagct tggatttttt ctatactgag
    20641 tatcaccttc atatatatta gctatattaa atagtttacc ttcttcaaac attgagccta
    20701 caaaagtaat gccgactggc tctccgttac ttttatagcc agcaggaact gtaagagctg
    20761 gataaccagc aggtgcatat gctatggcag cttgattact taatgaaact attacatctg
    20821 agctttttaa tatagtatct atttccttgc ttgctatttt tttattggat tcaattagtt
    20881 tattatattc ttct
//
