LOCUS       NC_015687.1            21757 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_015687.1 Clostridium acetobutylicum DSM 1731, complete sequence.
ACCESSION   NC_015687
VERSION     NC_015687.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 15:30:49
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2374119
            Orig. end    :: 2395876
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21757
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[2384119:2385876]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11757
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..21757
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21757
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="ranthipeptide"
                     /region_number="4"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /tool="antismash"
     CDS             complement(1112..2542)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2266"
                     /sec_met_domain="PF04055 (E-value: 1.1e-22, bitscore: 79.0,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKIKISDEAHSYAVYHMAILFFDEVKIVKSTLWDYSIVFNNESM
                     EICSKESEPENYKFDLRLNINENVKMAVFKYFSGLTGKRNIPWGTLIGIRPSKIASKLL
                     EENKSDKEIIEYFKVHNSTDEKKAKLCIEVSKNEKKFLKSVDNSVSIYLGMPFCPTRCR
                     YCSFISDTISHCKSYVDDYLKAMMYDIEKTSSYIRQRGLKIGCVYFGGGTPTSVSDEQF
                     ETIMKSVYESFIEGNNVKEFTVECGRPDSITRKKLLTMKKYKVHRISINPQTMNDETIK
                     SMGRGHTSKDVIDAFNMAREIGFDNINMDIIIGLPGENLDKINNTCIEILKLKPESLTI
                     HGLSLKRGSKLFEDMLEDKRIEAPNQDDIVNMFEKAYSCARELNMKPYYMYRQKNMVGN
                     MENVGYSLEGKECIYNIQMIEDSQPIIAIGCHGVSKILFKETNRIERYPNLKDVKEYIN
                     RIEEKVNGKIYFLKTLYG"
     aSDomain        complement(1142..2344)
                     /aSDomain="TIGR03994"
                     /aSTool="tigrfam"
                     /description="rSAM_HemZ: coproporphyrinogen dehydrogenase
                     HemZ"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2266_0013"
                     /evalue="8.80E-158"
                     /identifier="TIGR03994"
                     /label="ctg1_2266"
                     /locus_tag="ctg1_2266"
                     /protein_end="467"
                     /protein_start="66"
                     /score="523.6"
                     /tool="antismash"
                     /translation="ENVKMAVFKYFSGLTGKRNIPWGTLIGIRPSKIASKLLEENKSDK
                     EIIEYFKVHNSTDEKKAKLCIEVSKNEKKFLKSVDNSVSIYLGMPFCPTRCRYCSFISD
                     TISHCKSYVDDYLKAMMYDIEKTSSYIRQRGLKIGCVYFGGGTPTSVSDEQFETIMKSV
                     YESFIEGNNVKEFTVECGRPDSITRKKLLTMKKYKVHRISINPQTMNDETIKSMGRGHT
                     SKDVIDAFNMAREIGFDNINMDIIIGLPGENLDKINNTCIEILKLKPESLTIHGLSLKR
                     GSKLFEDMLEDKRIEAPNQDDIVNMFEKAYSCARELNMKPYYMYRQKNMVGNMENVGYS
                     LEGKECIYNIQMIEDSQPIIAIGCHGVSKILFKETNRIERYPNLKDVKEYINRIEEKVN
                     GK"
     PFAM_domain     complement(1565..2080)
                     /aSDomain="Radical_SAM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04055.23"
                     /description="Radical SAM superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2266_0087"
                     /evalue="4.70E-22"
                     /label="ctg1_2266"
                     /locus_tag="ctg1_2266"
                     /protein_end="326"
                     /protein_start="154"
                     /score="79.2"
                     /tool="antismash"
                     /translation="MPFCPTRCRYCSFISDTISHCKSYVDDYLKAMMYDIEKTSSYIRQ
                     RGLKIGCVYFGGGTPTSVSDEQFETIMKSVYESFIEGNNVKEFTVECGRPDSITRKKLL
                     TMKKYKVHRISINPQTMNDETIKSMGRGHTSKDVIDAFNMAREIGFDNINMDIIIGLPG
                     ENLDKINNT"
     CDS             complement(2563..3162)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1170:metallo-beta-lactamase family protein (Score:
                     171.4; E-value: 2.8e-52)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2267"
                     /transl_table=11
                     /translation="MKISVIQAGAYMTNCYILVDEKSNESVVIDPGDAPQAILEAFKDT
                     ETNLKFVLLTHGHADHTAAVAELKKEYNVDVYMNKDDCKLIENGEYMFGDKSENATKYV
                     DDGDELQFGELKIKCIKTPGHTPGGMCYLVDNYLFSGDTLFNSSIGRTDFPGGDFSTLI
                     NSIKSKLMKLDENIVVYPGHGEGTTIGYEKIHNPFI"
     PFAM_domain     complement(2614..3138)
                     /aSDomain="Lactamase_B"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00753.29"
                     /description="Metallo-beta-lactamase superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2267_0088"
                     /evalue="1.60E-28"
                     /label="ctg1_2267"
                     /locus_tag="ctg1_2267"
                     /protein_end="183"
                     /protein_start="8"
                     /score="100.1"
                     /tool="antismash"
                     /translation="GAYMTNCYILVDEKSNESVVIDPGDAPQAILEAFKDTETNLKFVL
                     LTHGHADHTAAVAELKKEYNVDVYMNKDDCKLIENGEYMFGDKSENATKYVDDGDELQF
                     GELKIKCIKTPGHTPGGMCYLVDNYLFSGDTLFNSSIGRTDFPGGDFSTLINSIKSKLM
                     KLDENIVVYPGH"
     CDS             complement(3173..3622)
                     /locus_tag="ctg1_2268"
                     /transl_table=11
                     /translation="MRAVVQKVKKSSVKVDGKVVGQIGKGINALIGITEGDTLEDIEYL
                     KNKILNLRIFEDEEGKLNKSLKDVNGELLVISQFTLYGDCRRGRRPSFIEALSGDKSEK
                     IYNDFVDLCRKEVPNVQTGVFGAHMDVDIQNDGPVTLLIDSKKVF"
     aSDomain        complement(3188..3622)
                     /aSDomain="TIGR00256"
                     /aSTool="tigrfam"
                     /description="TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2268_0014"
                     /evalue="1.80E-55"
                     /identifier="TIGR00256"
                     /label="ctg1_2268"
                     /locus_tag="ctg1_2268"
                     /protein_end="145"
                     /protein_start="0"
                     /score="185.4"
                     /tool="antismash"
                     /translation="MRAVVQKVKKSSVKVDGKVVGQIGKGINALIGITEGDTLEDIEYL
                     KNKILNLRIFEDEEGKLNKSLKDVNGELLVISQFTLYGDCRRGRRPSFIEALSGDKSEK
                     IYNDFVDLCRKEVPNVQTGVFGAHMDVDIQNDGPVTLLIDS"
     PFAM_domain     complement(3191..3619)
                     /aSDomain="Tyr_Deacylase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02580.18"
                     /description="D-Tyr-tRNA(Tyr) deacylase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2268_0089"
                     /evalue="1.60E-56"
                     /label="ctg1_2268"
                     /locus_tag="ctg1_2268"
                     /protein_end="144"
                     /protein_start="1"
                     /score="190.9"
                     /tool="antismash"
                     /translation="RAVVQKVKKSSVKVDGKVVGQIGKGINALIGITEGDTLEDIEYLK
                     NKILNLRIFEDEEGKLNKSLKDVNGELLVISQFTLYGDCRRGRRPSFIEALSGDKSEKI
                     YNDFVDLCRKEVPNVQTGVFGAHMDVDIQNDGPVTLLID"
     CDS             complement(3633..5855)
                     /locus_tag="ctg1_2269"
                     /transl_table=11
                     /translation="MAELSDLLEKIDENCNNVDKDIVIKAYNFAYEAHKHQMRESGEPY
                     ISHPLDVACILAEMGMDMSTIVAGILHDVIEDTSYSYDDITEMFSKEVADLVSGVTKLD
                     KITYKTKEEQQADNVRKMLLAMAKDIRVILIKLADRLHNMRTLKFKREQKQKEKAKETL
                     DIYAPLAHRLGMSKIKWELEDLSFRYLKPKEYYELVDLIAEKRVEREEYISKIVEELKL
                     NLEASGITPDIDGRPKHFYSIYRKMLNKSKSLDQIFDLTAVRILVNNIKECYAALGIVH
                     TMYKPIPGRFKDYIAMPKPNMYQSLHSTVIGPEGKPFEIQIRTYDMHKTAEYGIAAHWK
                     YKEGTIESTQNVPQNKNANKDDTKLTWIREMLEWQRETPSAQEFMENFKIDLFSDEIFV
                     FTPKGKVINLPYNATPVDFAYKIHTDIGNRCVGAKVNGKIVPLDYKLKTGEIVDILTTS
                     LVKGPNINWLNSVTSNQAKSKIRSWFKKAKRDENISKGKELLEKESKKQEFNFGEIAKG
                     ENLELVLKRYNMNSIDDLYASVGIGAVGASVILSRFKDIYEKNKDNGSLTNEEVLENVN
                     KNIHKEHSSKKISKSEQPGVTVKGVSDVLVRFAKCCTPVPGDPIIGYITKGRGVSVHRT
                     DCTNVNNLIKEDSSRIIEVKWGKSKNESYMAEVEIKAEDRQALLADVVEVISYMEIAIE
                     SVNAKTSKGSAYLNLKLKIQDVEHLALLMKKLRRLPGIIDIYRTNS"
     PFAM_domain     complement(3645..3875)
                     /aSDomain="ACT_4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13291.8"
                     /description="ACT domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2269_0094"
                     /evalue="1.40E-21"
                     /label="ctg1_2269"
                     /locus_tag="ctg1_2269"
                     /protein_end="737"
                     /protein_start="660"
                     /score="76.9"
                     /tool="antismash"
                     /translation="NESYMAEVEIKAEDRQALLADVVEVISYMEIAIESVNAKTSKGSA
                     YLNLKLKIQDVEHLALLMKKLRRLPGIIDIYR"
     aSDomain        complement(3645..5780)
                     /aSDomain="TIGR00691"
                     /aSTool="tigrfam"
                     /description="spoT_relA: RelA/SpoT family protein"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2269_0015"
                     /evalue="2.30E-255"
                     /identifier="TIGR00691"
                     /label="ctg1_2269"
                     /locus_tag="ctg1_2269"
                     /protein_end="737"
                     /protein_start="25"
                     /score="847.1"
                     /tool="antismash"
                     /translation="AYNFAYEAHKHQMRESGEPYISHPLDVACILAEMGMDMSTIVAGI
                     LHDVIEDTSYSYDDITEMFSKEVADLVSGVTKLDKITYKTKEEQQADNVRKMLLAMAKD
                     IRVILIKLADRLHNMRTLKFKREQKQKEKAKETLDIYAPLAHRLGMSKIKWELEDLSFR
                     YLKPKEYYELVDLIAEKRVEREEYISKIVEELKLNLEASGITPDIDGRPKHFYSIYRKM
                     LNKSKSLDQIFDLTAVRILVNNIKECYAALGIVHTMYKPIPGRFKDYIAMPKPNMYQSL
                     HSTVIGPEGKPFEIQIRTYDMHKTAEYGIAAHWKYKEGTIESTQNVPQNKNANKDDTKL
                     TWIREMLEWQRETPSAQEFMENFKIDLFSDEIFVFTPKGKVINLPYNATPVDFAYKIHT
                     DIGNRCVGAKVNGKIVPLDYKLKTGEIVDILTTSLVKGPNINWLNSVTSNQAKSKIRSW
                     FKKAKRDENISKGKELLEKESKKQEFNFGEIAKGENLELVLKRYNMNSIDDLYASVGIG
                     AVGASVILSRFKDIYEKNKDNGSLTNEEVLENVNKNIHKEHSSKKISKSEQPGVTVKGV
                     SDVLVRFAKCCTPVPGDPIIGYITKGRGVSVHRTDCTNVNNLIKEDSSRIIEVKWGKSK
                     NESYMAEVEIKAEDRQALLADVVEVISYMEIAIESVNAKTSKGSAYLNLKLKIQDVEHL
                     ALLMKKLRRLPGIIDIYR"
     PFAM_domain     complement(3948..4442)
                     /aSDomain="DUF5913"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF19296.1"
                     /description="Domain of unknown function (DUF5913)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2269_0093"
                     /evalue="8.30E-15"
                     /label="ctg1_2269"
                     /locus_tag="ctg1_2269"
                     /protein_end="636"
                     /protein_start="471"
                     /score="55.4"
                     /tool="antismash"
                     /translation="TSNQAKSKIRSWFKKAKRDENISKGKELLEKESKKQEFNFGEIAK
                     GENLELVLKRYNMNSIDDLYASVGIGAVGASVILSRFKDIYEKNKDNGSLTNEEVLENV
                     NKNIHKEHSSKKISKSEQPGVTVKGVSDVLVRFAKCCTPVPGDPIIGYITKGRGVSVHR
                     TD"
     PFAM_domain     complement(4488..4667)
                     /aSDomain="TGS"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02824.23"
                     /description="TGS domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2269_0092"
                     /evalue="9.40E-23"
                     /label="ctg1_2269"
                     /locus_tag="ctg1_2269"
                     /protein_end="456"
                     /protein_start="396"
                     /score="80.1"
                     /tool="antismash"
                     /translation="IFVFTPKGKVINLPYNATPVDFAYKIHTDIGNRCVGAKVNGKIVP
                     LDYKLKTGEIVDILT"
     PFAM_domain     complement(4824..5153)
                     /aSDomain="RelA_SpoT"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04607.19"
                     /description="Region found in RelA / SpoT proteins"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2269_0091"
                     /evalue="3.40E-37"
                     /label="ctg1_2269"
                     /locus_tag="ctg1_2269"
                     /protein_end="344"
                     /protein_start="234"
                     /score="127.4"
                     /tool="antismash"
                     /translation="GRPKHFYSIYRKMLNKSKSLDQIFDLTAVRILVNNIKECYAALGI
                     VHTMYKPIPGRFKDYIAMPKPNMYQSLHSTVIGPEGKPFEIQIRTYDMHKTAEYGIAAH
                     WKYKEG"
     PFAM_domain     complement(5331..5780)
                     /aSDomain="HD_4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13328.8"
                     /description="HD domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2269_0090"
                     /evalue="5.60E-52"
                     /label="ctg1_2269"
                     /locus_tag="ctg1_2269"
                     /protein_end="175"
                     /protein_start="25"
                     /score="175.7"
                     /tool="antismash"
                     /translation="AYNFAYEAHKHQMRESGEPYISHPLDVACILAEMGMDMSTIVAGI
                     LHDVIEDTSYSYDDITEMFSKEVADLVSGVTKLDKITYKTKEEQQADNVRKMLLAMAKD
                     IRVILIKLADRLHNMRTLKFKREQKQKEKAKETLDIYAPLAHRLGM"
     CDS             complement(5990..6508)
                     /locus_tag="ctg1_2270"
                     /transl_table=11
                     /translation="MDLKDSIRVIDGFPKEGISFKDVTTLIQDKEAYKYSVDKIGEYLK
                     DKNVDLIVAPEARGFLFGAPVAYKIGAGFIPVRKKGKLPCETVEVTYELEYGEDILEMH
                     KDAIKKGQRVAIVDDLLATGGTINSVAKLVEALGGEVVAACFVVELTDLNGKDKLGDYD
                     TMSLVKYNV"
     aSDomain        complement(5999..6502)
                     /aSDomain="TIGR01090"
                     /aSTool="tigrfam"
                     /description="apt: adenine phosphoribosyltransferase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2270_0016"
                     /evalue="5.40E-70"
                     /identifier="TIGR01090"
                     /label="ctg1_2270"
                     /locus_tag="ctg1_2270"
                     /protein_end="170"
                     /protein_start="2"
                     /score="232.8"
                     /tool="antismash"
                     /translation="LKDSIRVIDGFPKEGISFKDVTTLIQDKEAYKYSVDKIGEYLKDK
                     NVDLIVAPEARGFLFGAPVAYKIGAGFIPVRKKGKLPCETVEVTYELEYGEDILEMHKD
                     AIKKGQRVAIVDDLLATGGTINSVAKLVEALGGEVVAACFVVELTDLNGKDKLGDYDTM
                     SLVKY"
     PFAM_domain     complement(6020..6385)
                     /aSDomain="Pribosyltran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00156.29"
                     /description="Phosphoribosyl transferase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2270_0095"
                     /evalue="8.50E-15"
                     /label="ctg1_2270"
                     /locus_tag="ctg1_2270"
                     /protein_end="163"
                     /protein_start="41"
                     /score="54.6"
                     /tool="antismash"
                     /translation="EYLKDKNVDLIVAPEARGFLFGAPVAYKIGAGFIPVRKKGKLPCE
                     TVEVTYELEYGEDILEMHKDAIKKGQRVAIVDDLLATGGTINSVAKLVEALGGEVVAAC
                     FVVELTDLNGKDKLGDYD"
     CDS             complement(6617..7486)
                     /locus_tag="ctg1_2271"
                     /transl_table=11
                     /translation="MERTGDKLQYFGLKGMHNPFLIEGMNEALQRIAKAINNREKIVLY
                     GYCDVDSIIGMSIMLLVLKYLNADVEYLIPDDFCGSYEVNADYVNDKIKYFGANLLITI
                     GCGINSKESTALLKKLKIDTIVVDYHEMCNEEDYAIVVNPNRKESKYPFNEFCVSGIVF
                     KLCEAISMYYQMKCVNKYLDLAAIGTIHKCEELSGENKIIVDQGIRKIQNTNNYGIEAL
                     LKLKSVEKVDIDEVRKLSEAVVPTVNAVGKMDNARIIVQLFTTEDSYKAEQIAKYLNNE
                     FRYKGDFF"
     PFAM_domain     complement(6920..7366)
                     /aSDomain="DHH"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01368.22"
                     /description="DHH family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2271_0096"
                     /evalue="4.50E-12"
                     /label="ctg1_2271"
                     /locus_tag="ctg1_2271"
                     /protein_end="189"
                     /protein_start="40"
                     /score="46.4"
                     /tool="antismash"
                     /translation="KIVLYGYCDVDSIIGMSIMLLVLKYLNADVEYLIPDDFCGSYEVN
                     ADYVNDKIKYFGANLLITIGCGINSKESTALLKKLKIDTIVVDYHEMCNEEDYAIVVNP
                     NRKESKYPFNEFCVSGIVFKLCEAISMYYQMKCVNKYLDLAAIGT"
     CDS             complement(7591..8493)
                     /locus_tag="ctg1_2272"
                     /transl_table=11
                     /translation="MLKVIKHTKVWFGISLTIIFLGIAFMIYRGVTTGKPLEFGIDFVG
                     GNSMDIKIGKSFNKTDVEKIVDKYIKDSTITTVNNTEVEIKSSTMTDAIGNKIFKDMQK
                     KYNLKSKALVSQEKIGGTIGQELKTKALIALAIALVIILLYIAWRFEFKFGVAAMISLV
                     HDVLVTLAVYGIFAIPLNSPFIAGMLTIVGYSMSDTIVVFDRIRENSRKHRRMSTSEIA
                     DFSINETLTRSIYTVLTVLIAVSSVHVFVPSVRDFTKPLLVGIVSGCYSSIFIASPLWV
                     IFKERANKKKLQIKAEAQK"
     PFAM_domain     complement(7639..8193)
                     /aSDomain="SecD_SecF"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02355.18"
                     /description="Protein export membrane protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2272_0097"
                     /evalue="5.20E-59"
                     /label="ctg1_2272"
                     /locus_tag="ctg1_2272"
                     /protein_end="285"
                     /protein_start="100"
                     /score="198.9"
                     /tool="antismash"
                     /translation="DMQKKYNLKSKALVSQEKIGGTIGQELKTKALIALAIALVIILLY
                     IAWRFEFKFGVAAMISLVHDVLVTLAVYGIFAIPLNSPFIAGMLTIVGYSMSDTIVVFD
                     RIRENSRKHRRMSTSEIADFSINETLTRSIYTVLTVLIAVSSVHVFVPSVRDFTKPLLV
                     GIVSGCYSSIFIASPLWVIFKE"
     aSDomain        complement(7666..8385)
                     /aSDomain="TIGR00966"
                     /aSTool="tigrfam"
                     /description="3a0501s07: protein-export membrane protein
                     SecF"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2272_0017"
                     /evalue="1.70E-66"
                     /identifier="TIGR00966"
                     /label="ctg1_2272"
                     /locus_tag="ctg1_2272"
                     /protein_end="276"
                     /protein_start="36"
                     /score="222.5"
                     /tool="antismash"
                     /translation="LEFGIDFVGGNSMDIKIGKSFNKTDVEKIVDKYIKDSTITTVNNT
                     EVEIKSSTMTDAIGNKIFKDMQKKYNLKSKALVSQEKIGGTIGQELKTKALIALAIALV
                     IILLYIAWRFEFKFGVAAMISLVHDVLVTLAVYGIFAIPLNSPFIAGMLTIVGYSMSDT
                     IVVFDRIRENSRKHRRMSTSEIADFSINETLTRSIYTVLTVLIAVSSVHVFVPSVRDFT
                     KPLLVGIVSGCYSSIFIA"
     aSDomain        complement(7675..8301)
                     /aSDomain="TIGR00916"
                     /aSTool="tigrfam"
                     /description="2A0604s01: protein-export membrane protein,
                     SecD/SecF family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2272_0018"
                     /evalue="2.80E-46"
                     /identifier="TIGR00916"
                     /label="ctg1_2272"
                     /locus_tag="ctg1_2272"
                     /protein_end="273"
                     /protein_start="64"
                     /score="156.0"
                     /tool="antismash"
                     /translation="IVDKYIKDSTITTVNNTEVEIKSSTMTDAIGNKIFKDMQKKYNLK
                     SKALVSQEKIGGTIGQELKTKALIALAIALVIILLYIAWRFEFKFGVAAMISLVHDVLV
                     TLAVYGIFAIPLNSPFIAGMLTIVGYSMSDTIVVFDRIRENSRKHRRMSTSEIADFSIN
                     ETLTRSIYTVLTVLIAVSSVHVFVPSVRDFTKPLLVGIVSGCYSSI"
     CDS             complement(8493..9746)
                     /locus_tag="ctg1_2273"
                     /transl_table=11
                     /translation="MKKKGRSTIFFIISVLIIAGLAYLGSTGLNVGDYRIKSFTESIDK
                     GLDLQGGVSVVEEIQGKVNSDAMGRTIELLNLRVNKLGVSETTVSRVGNNKIEIDVPGM
                     YNKDEVINKIGKTGKLKFVGPDKKTVLTGSDVKKATAGTDPNTNQPIISLQLNSSGTKK
                     FADATQKFLGQKISIYMDTDLLSDPTVDSVITGGNAQITGNKSIQEAQRIANIINSGAL
                     PVTLKVVQSKTVGASLGASALPNSILAGAVAICIIFLFMILVYRIPGLMADIALVLFTV
                     LVLGAFVAVKVTLTLSGIAGLLLTIGMAVDANVLIFERFKEELKIGKTVRSAFDAGFHR
                     AMSSIIDSNVTTIISGVILYALGSGEVKGFALTLVIGVLISMVTAIIVTRRLLMWAIDM
                     GLINKASHFGVNLEGSGK"
     PFAM_domain     complement(8559..9071)
                     /aSDomain="SecD_SecF"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02355.18"
                     /description="Protein export membrane protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2273_0098"
                     /evalue="1.40E-17"
                     /label="ctg1_2273"
                     /locus_tag="ctg1_2273"
                     /protein_end="396"
                     /protein_start="225"
                     /score="63.8"
                     /tool="antismash"
                     /translation="LKVVQSKTVGASLGASALPNSILAGAVAICIIFLFMILVYRIPGL
                     MADIALVLFTVLVLGAFVAVKVTLTLSGIAGLLLTIGMAVDANVLIFERFKEELKIGKT
                     VRSAFDAGFHRAMSSIIDSNVTTIISGVILYALGSGEVKGFALTLVIGVLISMVTAIIV
                     TRRLLMWA"
     aSDomain        complement(8568..9368)
                     /aSDomain="TIGR01129"
                     /aSTool="tigrfam"
                     /description="secD: protein-export membrane protein SecD"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2273_0019"
                     /evalue="8.00E-97"
                     /identifier="TIGR01129"
                     /label="ctg1_2273"
                     /locus_tag="ctg1_2273"
                     /protein_end="393"
                     /protein_start="126"
                     /score="322.8"
                     /tool="antismash"
                     /translation="KKTVLTGSDVKKATAGTDPNTNQPIISLQLNSSGTKKFADATQKF
                     LGQKISIYMDTDLLSDPTVDSVITGGNAQITGNKSIQEAQRIANIINSGALPVTLKVVQ
                     SKTVGASLGASALPNSILAGAVAICIIFLFMILVYRIPGLMADIALVLFTVLVLGAFVA
                     VKVTLTLSGIAGLLLTIGMAVDANVLIFERFKEELKIGKTVRSAFDAGFHRAMSSIIDS
                     NVTTIISGVILYALGSGEVKGFALTLVIGVLISMVTAIIVTRRLL"
     aSDomain        complement(8589..9281)
                     /aSDomain="TIGR00916"
                     /aSTool="tigrfam"
                     /description="2A0604s01: protein-export membrane protein,
                     SecD/SecF family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2273_0020"
                     /evalue="1.60E-70"
                     /identifier="TIGR00916"
                     /label="ctg1_2273"
                     /locus_tag="ctg1_2273"
                     /protein_end="386"
                     /protein_start="155"
                     /score="235.3"
                     /tool="antismash"
                     /translation="LNSSGTKKFADATQKFLGQKISIYMDTDLLSDPTVDSVITGGNAQ
                     ITGNKSIQEAQRIANIINSGALPVTLKVVQSKTVGASLGASALPNSILAGAVAICIIFL
                     FMILVYRIPGLMADIALVLFTVLVLGAFVAVKVTLTLSGIAGLLLTIGMAVDANVLIFE
                     RFKEELKIGKTVRSAFDAGFHRAMSSIIDSNVTTIISGVILYALGSGEVKGFALTLVIG
                     VLISMVTAI"
     CDS             complement(10001..11365)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SPASM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2274"
                     /sec_met_domain="PF04055 (E-value: 2.1e-15, bitscore: 55.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 8.7e-13, bitscore: 46.5,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 5.2e-21, bitscore:
                     72.6, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 3.8e-07, bitscore: 28.3,
                     seeds: 166, tool: rule-based-clusters)"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 5.9e-28,
                     bitscore: 94.8, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LSLVHKFIQDDQRYIIDVNSGSIHEVDEMVYDLIDEDKIRSKKKL
                     LDRLKNKYKEEEISEAYDEIKELIDEGVLYSKDLYEDIAKESTKSPSFIKALCLNIAHD
                     CNLKCKYCFADEGEYKGCREIMSPEVAKKSIDFVIKHSGPRKNIEVDLFGGEPLMAFDT
                     IKQVVEYAKKEEKKYNKNIRFTMTTNATLLNDEIMDYLDKNMGNIILSFDGRKEVNDKV
                     RVRADGTGSHDAILKNIKKMVARRDKSKQYYVRGTFTRNNTDFFEDVKYIADMGFKEIS
                     IEPVVLPDDHNLSLREEDIPQIFEQYDKLYKDMIKRHKEGKEIKFYHFNIDINGGPCVY
                     KRISGCGAGHEYVSITPSGDVYPCHQFVGNEDFKMGTIYDDDNINKEMGNEFREAHIYN
                     KPKCRECWARFYCSGGCQANNYNFNGDMHIPYEIGCKMQKKRIECAIALKAQMVD"
     aSDomain        complement(10016..11356)
                     /aSDomain="TIGR03974"
                     /aSTool="tigrfam"
                     /description="rSAM_six_Cys: SCIFF radical SAM maturase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2274_0021"
                     /evalue="7.00E-200"
                     /identifier="TIGR03974"
                     /label="ctg1_2274"
                     /locus_tag="ctg1_2274"
                     /protein_end="450"
                     /protein_start="3"
                     /score="662.5"
                     /tool="antismash"
                     /translation="VHKFIQDDQRYIIDVNSGSIHEVDEMVYDLIDEDKIRSKKKLLDR
                     LKNKYKEEEISEAYDEIKELIDEGVLYSKDLYEDIAKESTKSPSFIKALCLNIAHDCNL
                     KCKYCFADEGEYKGCREIMSPEVAKKSIDFVIKHSGPRKNIEVDLFGGEPLMAFDTIKQ
                     VVEYAKKEEKKYNKNIRFTMTTNATLLNDEIMDYLDKNMGNIILSFDGRKEVNDKVRVR
                     ADGTGSHDAILKNIKKMVARRDKSKQYYVRGTFTRNNTDFFEDVKYIADMGFKEISIEP
                     VVLPDDHNLSLREEDIPQIFEQYDKLYKDMIKRHKEGKEIKFYHFNIDINGGPCVYKRI
                     SGCGAGHEYVSITPSGDVYPCHQFVGNEDFKMGTIYDDDNINKEMGNEFREAHIYNKPK
                     CRECWARFYCSGGCQANNYNFNGDMHIPYEIGCKMQKKRIECAIALKA"
     aSDomain        complement(10076..10330)
                     /aSDomain="TIGR04085"
                     /aSTool="tigrfam"
                     /description="rSAM_more_4Fe4S: radical SAM additional
                     4Fe4S-binding SPASM domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2274_0022"
                     /evalue="6.30E-21"
                     /identifier="TIGR04085"
                     /label="ctg1_2274"
                     /locus_tag="ctg1_2274"
                     /protein_end="430"
                     /protein_start="345"
                     /score="72.6"
                     /tool="antismash"
                     /translation="CGAGHEYVSITPSGDVYPCHQFVGNEDFKMGTIYDDDNINKEMGN
                     EFREAHIYNKPKCRECWARFYCSGGCQANNYNFNGDMHIP"
     PFAM_domain     complement(10145..10330)
                     /aSDomain="SPASM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13186.8"
                     /description="Iron-sulfur cluster-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2274_0100"
                     /evalue="2.20E-06"
                     /label="ctg1_2274"
                     /locus_tag="ctg1_2274"
                     /protein_end="407"
                     /protein_start="345"
                     /score="28.1"
                     /tool="antismash"
                     /translation="CGAGHEYVSITPSGDVYPCHQFVGNEDFKMGTIYDDDNINKEMGN
                     EFREAHIYNKPKCRECW"
     PFAM_domain     complement(10760..11065)
                     /aSDomain="Fer4_12"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13353.8"
                     /description="4Fe-4S single cluster domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2274_0099"
                     /evalue="1.30E-12"
                     /label="ctg1_2274"
                     /locus_tag="ctg1_2274"
                     /protein_end="202"
                     /protein_start="100"
                     /score="48.5"
                     /tool="antismash"
                     /translation="IAHDCNLKCKYCFADEGEYKGCREIMSPEVAKKSIDFVIKHSGPR
                     KNIEVDLFGGEPLMAFDTIKQVVEYAKKEEKKYNKNIRFTMTTNATLLNDEIMDYLD"
     CDS             complement(11617..11757)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR03973"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SCIFF"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2275"
                     /sec_met_domain="TIGR03973 (E-value: 2.7e-23, bitscore:
                     79.4, seeds: 29, tool: rule-based-clusters)"
                     /sec_met_domain="SCIFF (E-value: 4.5e-22, bitscore: 75.5,
                     seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHIKSINKSNIKESLKKPGCKECANSCQSACKTSCTVANLACES
                     K"
     aSDomain        complement(11626..11754)
                     /aSDomain="TIGR03973"
                     /aSTool="tigrfam"
                     /description="six_Cys_in_45: six-cysteine peptide SCIFF"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2275_0023"
                     /evalue="3.20E-23"
                     /identifier="TIGR03973"
                     /label="ctg1_2275"
                     /locus_tag="ctg1_2275"
                     /protein_end="44"
                     /protein_start="1"
                     /score="79.4"
                     /tool="antismash"
                     /translation="KHIKSINKSNIKESLKKPGCKECANSCQSACKTSCTVANLACE"
     PFAM_domain     complement(11626..11754)
                     /aSDomain="SCIFF"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13165.8"
                     /description="Six-cysteine peptide SCIFF"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2275_0101"
                     /evalue="2.20E-21"
                     /label="ctg1_2275"
                     /locus_tag="ctg1_2275"
                     /protein_end="44"
                     /protein_start="1"
                     /score="75.6"
                     /tool="antismash"
                     /translation="KHIKSINKSNIKESLKKPGCKECANSCQSACKTSCTVANLACE"
     CDS             complement(11825..12196)
                     /locus_tag="ctg1_2276"
                     /transl_table=11
                     /translation="LEKSSKIYVSAAGGVLRAIFVTLIVILIFSFVSTKISFSEGITNM
                     VILVTTLLSVMYGSIYSSRKSGKKGWLNGLLVGLFYILIFYIVSLVDGSSGGMQLRDFI
                     RVTLAIVVGILSGMLGINI"
     aSDomain        complement(11828..12160)
                     /aSDomain="TIGR04086"
                     /aSTool="tigrfam"
                     /description="TIGR04086_membr: putative membrane protein,
                     TIGR04086 family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2276_0024"
                     /evalue="6.40E-29"
                     /identifier="TIGR04086"
                     /label="ctg1_2276"
                     /locus_tag="ctg1_2276"
                     /protein_end="123"
                     /protein_start="12"
                     /score="98.4"
                     /tool="antismash"
                     /translation="GGVLRAIFVTLIVILIFSFVSTKISFSEGITNMVILVTTLLSVMY
                     GSIYSSRKSGKKGWLNGLLVGLFYILIFYIVSLVDGSSGGMQLRDFIRVTLAIVVGILS
                     GMLGINI"
     PFAM_domain     complement(11837..12160)
                     /aSDomain="DUF3792"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12670.9"
                     /description="Protein of unknown function (DUF3792)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2276_0102"
                     /evalue="3.60E-24"
                     /label="ctg1_2276"
                     /locus_tag="ctg1_2276"
                     /protein_end="120"
                     /protein_start="12"
                     /score="85.2"
                     /tool="antismash"
                     /translation="GGVLRAIFVTLIVILIFSFVSTKISFSEGITNMVILVTTLLSVMY
                     GSIYSSRKSGKKGWLNGLLVGLFYILIFYIVSLVDGSSGGMQLRDFIRVTLAIVVGILS
                     GMLG"
     CDS             complement(12286..12570)
                     /locus_tag="ctg1_2277"
                     /transl_table=11
                     /translation="MPNTVLTILYVVFLLGMFYVAMYIPDRAKKKKFNKMLSEMRVNDK
                     VVTTGGIMGQITNIQEQFVIIQTGPDKVKIKIKKEAIATVETRKADNQK"
     aSDomain        complement(12316..12558)
                     /aSDomain="TIGR00739"
                     /aSTool="tigrfam"
                     /description="yajC: preprotein translocase, YajC subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2277_0025"
                     /evalue="3.50E-17"
                     /identifier="TIGR00739"
                     /label="ctg1_2277"
                     /locus_tag="ctg1_2277"
                     /protein_end="85"
                     /protein_start="4"
                     /score="60.3"
                     /tool="antismash"
                     /translation="VLTILYVVFLLGMFYVAMYIPDRAKKKKFNKMLSEMRVNDKVVTT
                     GGIMGQITNIQEQFVIIQTGPDKVKIKIKKEAIATV"
     PFAM_domain     complement(12322..12552)
                     /aSDomain="YajC"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02699.17"
                     /description="Preprotein translocase subunit"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2277_0103"
                     /evalue="8.00E-22"
                     /label="ctg1_2277"
                     /locus_tag="ctg1_2277"
                     /protein_end="83"
                     /protein_start="6"
                     /score="77.0"
                     /tool="antismash"
                     /translation="TILYVVFLLGMFYVAMYIPDRAKKKKFNKMLSEMRVNDKVVTTGG
                     IMGQITNIQEQFVIIQTGPDKVKIKIKKEAIA"
     CDS             complement(12603..13733)
                     /locus_tag="ctg1_2278"
                     /transl_table=11
                     /translation="LYTLLKKTGKVRRGRFETVHGTIETPVFMNVGTLAAIKGAVSSMD
                     LKEINCQVELSNTYHLSLRPGDDVVKKLGGLHKFMNWDRPILTDSGGFQVFSLAEIRKI
                     KEEGVYFNSHIDGRKIFMGPEESMKIQSNLASTIAMAFDECVENPSPREYVERSVERTT
                     RWLVRCKEELDRLNSLPDTINKKQMLFGINQGGVYDDIRIEHAKTIAKMDLDGYAIGGL
                     AVGETHEEMYRIIDAVVPHLPQDKPIYLMGVGTPSNILEAVSRGVDFFDCVLPARNGRH
                     GHVFTKHGKINLRNEKFELDASPIDEGCQCPTCKHYSRAYIRHLFKAKEMLAMRLCVLH
                     NLYFYNTLMEDIRNAIDADCFEEFKNEKLKAWAGKA"
     PFAM_domain     complement(12618..13703)
                     /aSDomain="TGT"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01702.20"
                     /description="Queuine tRNA-ribosyltransferase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2278_0104"
                     /evalue="5.60E-150"
                     /label="ctg1_2278"
                     /locus_tag="ctg1_2278"
                     /protein_end="372"
                     /protein_start="10"
                     /score="499.5"
                     /tool="antismash"
                     /translation="VRRGRFETVHGTIETPVFMNVGTLAAIKGAVSSMDLKEINCQVEL
                     SNTYHLSLRPGDDVVKKLGGLHKFMNWDRPILTDSGGFQVFSLAEIRKIKEEGVYFNSH
                     IDGRKIFMGPEESMKIQSNLASTIAMAFDECVENPSPREYVERSVERTTRWLVRCKEEL
                     DRLNSLPDTINKKQMLFGINQGGVYDDIRIEHAKTIAKMDLDGYAIGGLAVGETHEEMY
                     RIIDAVVPHLPQDKPIYLMGVGTPSNILEAVSRGVDFFDCVLPARNGRHGHVFTKHGKI
                     NLRNEKFELDASPIDEGCQCPTCKHYSRAYIRHLFKAKEMLAMRLCVLHNLYFYNTLME
                     DIRNAIDADCFEEFKNEKLKAW"
     aSDomain        complement(12621..13730)
                     /aSDomain="TIGR00449"
                     /aSTool="tigrfam"
                     /description="tgt_general: tRNA-guanine family
                     transglycosylase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2278_0027"
                     /evalue="5.00E-146"
                     /identifier="TIGR00449"
                     /label="ctg1_2278"
                     /locus_tag="ctg1_2278"
                     /protein_end="371"
                     /protein_start="1"
                     /score="484.2"
                     /tool="antismash"
                     /translation="YTLLKKTGKVRRGRFETVHGTIETPVFMNVGTLAAIKGAVSSMDL
                     KEINCQVELSNTYHLSLRPGDDVVKKLGGLHKFMNWDRPILTDSGGFQVFSLAEIRKIK
                     EEGVYFNSHIDGRKIFMGPEESMKIQSNLASTIAMAFDECVENPSPREYVERSVERTTR
                     WLVRCKEELDRLNSLPDTINKKQMLFGINQGGVYDDIRIEHAKTIAKMDLDGYAIGGLA
                     VGETHEEMYRIIDAVVPHLPQDKPIYLMGVGTPSNILEAVSRGVDFFDCVLPARNGRHG
                     HVFTKHGKINLRNEKFELDASPIDEGCQCPTCKHYSRAYIRHLFKAKEMLAMRLCVLHN
                     LYFYNTLMEDIRNAIDADCFEEFKNEKLKA"
     aSDomain        complement(12624..13730)
                     /aSDomain="TIGR00430"
                     /aSTool="tigrfam"
                     /description="Q_tRNA_tgt: tRNA-guanine transglycosylase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2278_0026"
                     /evalue="5.00E-153"
                     /identifier="TIGR00430"
                     /label="ctg1_2278"
                     /locus_tag="ctg1_2278"
                     /protein_end="370"
                     /protein_start="1"
                     /score="507.4"
                     /tool="antismash"
                     /translation="YTLLKKTGKVRRGRFETVHGTIETPVFMNVGTLAAIKGAVSSMDL
                     KEINCQVELSNTYHLSLRPGDDVVKKLGGLHKFMNWDRPILTDSGGFQVFSLAEIRKIK
                     EEGVYFNSHIDGRKIFMGPEESMKIQSNLASTIAMAFDECVENPSPREYVERSVERTTR
                     WLVRCKEELDRLNSLPDTINKKQMLFGINQGGVYDDIRIEHAKTIAKMDLDGYAIGGLA
                     VGETHEEMYRIIDAVVPHLPQDKPIYLMGVGTPSNILEAVSRGVDFFDCVLPARNGRHG
                     HVFTKHGKINLRNEKFELDASPIDEGCQCPTCKHYSRAYIRHLFKAKEMLAMRLCVLHN
                     LYFYNTLMEDIRNAIDADCFEEFKNEKLK"
     CDS             complement(13751..14776)
                     /locus_tag="ctg1_2279"
                     /transl_table=11
                     /translation="LQLEDFDYYLPEELIAQHPCDKRDECRLMVVDKKSGEVEHRIFKD
                     VIDYLNPGDCLVLNDTRVLPARLIGNKVGTGGKMEFLLLKRIDKDTWETLVKPGKRAKV
                     GAEFEFGGGVLKAVIKSIGEDGNRVVEFKYEGIFEEILDKLGQMPLPPYITEELENKEE
                     YQTVYSKNNGSAAAPTAGLHFTNELLDKIRAKGIKTVFLTLHVGLGTFRPVKVENIESH
                     HMHSEYYMLSKESADTINETRKNGGRIISVGTTSTRTLETIADEKGNVREQSGWTDIYI
                     YPGYKYKIVDGLITNFHLPKSTLVMLVSALSSRDNILNAYKIAVENRYRFFSFGDAMFI
                     K"
     PFAM_domain     complement(13757..14770)
                     /aSDomain="Queuosine_synth"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02547.17"
                     /description="Queuosine biosynthesis protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2279_0105"
                     /evalue="5.10E-143"
                     /label="ctg1_2279"
                     /locus_tag="ctg1_2279"
                     /protein_end="340"
                     /protein_start="2"
                     /score="476.2"
                     /tool="antismash"
                     /translation="LEDFDYYLPEELIAQHPCDKRDECRLMVVDKKSGEVEHRIFKDVI
                     DYLNPGDCLVLNDTRVLPARLIGNKVGTGGKMEFLLLKRIDKDTWETLVKPGKRAKVGA
                     EFEFGGGVLKAVIKSIGEDGNRVVEFKYEGIFEEILDKLGQMPLPPYITEELENKEEYQ
                     TVYSKNNGSAAAPTAGLHFTNELLDKIRAKGIKTVFLTLHVGLGTFRPVKVENIESHHM
                     HSEYYMLSKESADTINETRKNGGRIISVGTTSTRTLETIADEKGNVREQSGWTDIYIYP
                     GYKYKIVDGLITNFHLPKSTLVMLVSALSSRDNILNAYKIAVENRYRFFSFGDAMFI"
     aSDomain        complement(13757..14773)
                     /aSDomain="TIGR00113"
                     /aSTool="tigrfam"
                     /description="queA: S-adenosylmethionine:tRNA
                     ribosyltransferase-isomerase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2279_0028"
                     /evalue="2.70E-143"
                     /identifier="TIGR00113"
                     /label="ctg1_2279"
                     /locus_tag="ctg1_2279"
                     /protein_end="340"
                     /protein_start="1"
                     /score="475.1"
                     /tool="antismash"
                     /translation="QLEDFDYYLPEELIAQHPCDKRDECRLMVVDKKSGEVEHRIFKDV
                     IDYLNPGDCLVLNDTRVLPARLIGNKVGTGGKMEFLLLKRIDKDTWETLVKPGKRAKVG
                     AEFEFGGGVLKAVIKSIGEDGNRVVEFKYEGIFEEILDKLGQMPLPPYITEELENKEEY
                     QTVYSKNNGSAAAPTAGLHFTNELLDKIRAKGIKTVFLTLHVGLGTFRPVKVENIESHH
                     MHSEYYMLSKESADTINETRKNGGRIISVGTTSTRTLETIADEKGNVREQSGWTDIYIY
                     PGYKYKIVDGLITNFHLPKSTLVMLVSALSSRDNILNAYKIAVENRYRFFSFGDAMFI"
     CDS             complement(14813..15862)
                     /locus_tag="ctg1_2280"
                     /transl_table=11
                     /translation="MDDRILTSVNLEEDSAEYNLRPQKLNEYIGQSKVKEKMDIFIRAA
                     KKRGEALDHVLFYGPPGLGKTTLANIIAKEMGGNLKVTSGPAIERAGDLAAILTGLSEY
                     DVLFIDEIHRLNRSVEEILYPAMEDYALDIIIGKGAAAKSIRLDLPKFTLIGATTRVGL
                     LTAPLRDRFGVLCPMEFYNDEELKEIIVRSSSILDIDIDEDAALEIAMRSRGTPRIANR
                     LLKRVRDYADVKGRGIVNLDSAKKALNLLEVDDEGFDSIDNKIIQAIVNNFAGGPVGIE
                     TLSYFVGEEIDTIEDVYEPYLLQKGFIMRTPRGRMATKKAYEHLKVPFNMKKNGTVNND
                     QCSFFKKEK"
     PFAM_domain     complement(14885..15097)
                     /aSDomain="RuvB_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05491.15"
                     /description="RuvB C-terminal winged helix domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2280_0108"
                     /evalue="5.10E-27"
                     /label="ctg1_2280"
                     /locus_tag="ctg1_2280"
                     /protein_end="326"
                     /protein_start="255"
                     /score="93.7"
                     /tool="antismash"
                     /translation="EGFDSIDNKIIQAIVNNFAGGPVGIETLSYFVGEEIDTIEDVYEP
                     YLLQKGFIMRTPRGRMATKKAYEHLK"
     aSDomain        complement(14885..15796)
                     /aSDomain="TIGR00635"
                     /aSTool="tigrfam"
                     /description="ruvB: Holliday junction DNA helicase RuvB"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2280_0029"
                     /evalue="1.70E-145"
                     /identifier="TIGR00635"
                     /label="ctg1_2280"
                     /locus_tag="ctg1_2280"
                     /protein_end="326"
                     /protein_start="22"
                     /score="481.7"
                     /tool="antismash"
                     /translation="QKLNEYIGQSKVKEKMDIFIRAAKKRGEALDHVLFYGPPGLGKTT
                     LANIIAKEMGGNLKVTSGPAIERAGDLAAILTGLSEYDVLFIDEIHRLNRSVEEILYPA
                     MEDYALDIIIGKGAAAKSIRLDLPKFTLIGATTRVGLLTAPLRDRFGVLCPMEFYNDEE
                     LKEIIVRSSSILDIDIDEDAALEIAMRSRGTPRIANRLLKRVRDYADVKGRGIVNLDSA
                     KKALNLLEVDDEGFDSIDNKIIQAIVNNFAGGPVGIETLSYFVGEEIDTIEDVYEPYLL
                     QKGFIMRTPRGRMATKKAYEHLK"
     PFAM_domain     complement(15101..15322)
                     /aSDomain="AAA_lid_4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF17864.3"
                     /description="RuvB AAA lid domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2280_0107"
                     /evalue="4.70E-32"
                     /label="ctg1_2280"
                     /locus_tag="ctg1_2280"
                     /protein_end="254"
                     /protein_start="180"
                     /score="109.6"
                     /tool="antismash"
                     /translation="YNDEELKEIIVRSSSILDIDIDEDAALEIAMRSRGTPRIANRLLK
                     RVRDYADVKGRGIVNLDSAKKALNLLEVD"
     PFAM_domain     complement(15335..15805)
                     /aSDomain="RuvB_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05496.14"
                     /description="Holliday junction DNA helicase RuvB P-loop
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2280_0106"
                     /evalue="3.80E-82"
                     /label="ctg1_2280"
                     /locus_tag="ctg1_2280"
                     /protein_end="176"
                     /protein_start="19"
                     /score="273.8"
                     /tool="antismash"
                     /translation="LRPQKLNEYIGQSKVKEKMDIFIRAAKKRGEALDHVLFYGPPGLG
                     KTTLANIIAKEMGGNLKVTSGPAIERAGDLAAILTGLSEYDVLFIDEIHRLNRSVEEIL
                     YPAMEDYALDIIIGKGAAAKSIRLDLPKFTLIGATTRVGLLTAPLRDRFGVLC"
     CDS             complement(15875..16564)
                     /locus_tag="ctg1_2281"
                     /transl_table=11
                     /translation="MLRNLQVMIKRPVGFIFKMIIFYLGVTILYEYIKGKYIGINKDYI
                     IVDNNGVGYKIFTSGNTMANMPKPEEDVLIYLTQIVRQDFIGLYGFLTKDELEMFNKLL
                     TINGVGAKASLSLLSICTVNNLKYAIITGDEKTIVKAPGIGKKTAQRIILELKDKFKST
                     DISKGNSEINNLDVDYDEHSKKLEEVRFALNSLGYSEKETDRAINNVDKSEGIENIIKS
                     CLRFLMN"
     PFAM_domain     complement(15881..16009)
                     /aSDomain="RuvA_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07499.15"
                     /description="RuvA, C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2281_0111"
                     /evalue="2.10E-10"
                     /label="ctg1_2281"
                     /locus_tag="ctg1_2281"
                     /protein_end="228"
                     /protein_start="185"
                     /score="41.0"
                     /tool="antismash"
                     /translation="LEEVRFALNSLGYSEKETDRAINNVDKSEGIENIIKSCLRFLM"
     aSDomain        complement(15881..16471)
                     /aSDomain="TIGR00084"
                     /aSTool="tigrfam"
                     /description="ruvA: Holliday junction DNA helicase RuvA"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2281_0030"
                     /evalue="8.70E-46"
                     /identifier="TIGR00084"
                     /label="ctg1_2281"
                     /locus_tag="ctg1_2281"
                     /protein_end="228"
                     /protein_start="31"
                     /score="153.8"
                     /tool="antismash"
                     /translation="YIKGKYIGINKDYIIVDNNGVGYKIFTSGNTMANMPKPEEDVLIY
                     LTQIVRQDFIGLYGFLTKDELEMFNKLLTINGVGAKASLSLLSICTVNNLKYAIITGDE
                     KTIVKAPGIGKKTAQRIILELKDKFKSTDISKGNSEINNLDVDYDEHSKKLEEVRFALN
                     SLGYSEKETDRAINNVDKSEGIENIIKSCLRFLM"
     PFAM_domain     complement(16091..16267)
                     /aSDomain="HHH_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14520.8"
                     /description="Helix-hairpin-helix domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2281_0110"
                     /evalue="3.30E-16"
                     /label="ctg1_2281"
                     /locus_tag="ctg1_2281"
                     /protein_end="158"
                     /protein_start="99"
                     /score="59.6"
                     /tool="antismash"
                     /translation="FNKLLTINGVGAKASLSLLSICTVNNLKYAIITGDEKTIVKAPGI
                     GKKTAQRIILELKD"
     PFAM_domain     complement(16295..16477)
                     /aSDomain="RuvA_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01330.23"
                     /description="RuvA N terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2281_0109"
                     /evalue="3.60E-16"
                     /label="ctg1_2281"
                     /locus_tag="ctg1_2281"
                     /protein_end="90"
                     /protein_start="29"
                     /score="59.1"
                     /tool="antismash"
                     /translation="YEYIKGKYIGINKDYIIVDNNGVGYKIFTSGNTMANMPKPEEDVL
                     IYLTQIVRQDFIGLYG"
     CDS             complement(16536..17183)
                     /locus_tag="ctg1_2282"
                     /transl_table=11
                     /translation="MTLKKKVILSVVALLVTFIFSFCIGYRGNLIKIMNAEKYKISKGI
                     DEFLGRNESEKARYTSNNKEGKKTLALLIVKQNYDITFDPEDETKNNVLTSSEETNAEK
                     EHKAGMTKEQITRSYEKQGYIVIWDNDMKVEVIKNRYINNHKVDGVFILNKDKNSDKIN
                     VYKVDDNGSLIKTNEQAYISVNQLKNETRDLLRKGFLVFGSKEDAKKLAGYD"
     CDS             complement(17388..18743)
                     /locus_tag="ctg1_2283"
                     /transl_table=11
                     /translation="MKLEFTCGEEITIKEVNKLKLELMTSGKGDVEKELERLKKNKNKV
                     HDIKTEETIDLLDRCAKLWLDDNYSKKHIETLAQITNQSFELVNYEFKSMMQMLLRENI
                     QNTIKRELGEVDILDSWHKTNYGYEHRQPRGIIFHNISGNAFVVIPMSISMGLLSKNCN
                     LVKVSKDEPYFAYAFYKSLCELDETVKDRLSVLYFDSSKTEIYDTIVKNSDGVIHWGGE
                     YSSRIIGEMCAKYQKHMIMHGAKISFEVVDKCDDLNKVSEEIAKDIICWEQKACLSPRV
                     VFLNDKIDVDEFSHCLSASLRKITEVIPKAYLSEWNSVKTIQDRQYCTLKYGMKNERRF
                     KVYSSFNADYTVILSDGMPEKEDINKCFYRFIFVCPYSSKSDVVNYVSENLKDYLQTMG
                     YSGNDEEFIEKMTLLGVSIVTKPGKMSLHEPGTSHDGIHNLKEFTFLVSRQI"
     PFAM_domain     complement(17409..18611)
                     /aSDomain="LuxC"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05893.16"
                     /description="Acyl-CoA reductase (LuxC)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2283_0112"
                     /evalue="9.50E-161"
                     /label="ctg1_2283"
                     /locus_tag="ctg1_2283"
                     /protein_end="445"
                     /protein_start="44"
                     /score="535.3"
                     /tool="antismash"
                     /translation="VHDIKTEETIDLLDRCAKLWLDDNYSKKHIETLAQITNQSFELVN
                     YEFKSMMQMLLRENIQNTIKRELGEVDILDSWHKTNYGYEHRQPRGIIFHNISGNAFVV
                     IPMSISMGLLSKNCNLVKVSKDEPYFAYAFYKSLCELDETVKDRLSVLYFDSSKTEIYD
                     TIVKNSDGVIHWGGEYSSRIIGEMCAKYQKHMIMHGAKISFEVVDKCDDLNKVSEEIAK
                     DIICWEQKACLSPRVVFLNDKIDVDEFSHCLSASLRKITEVIPKAYLSEWNSVKTIQDR
                     QYCTLKYGMKNERRFKVYSSFNADYTVILSDGMPEKEDINKCFYRFIFVCPYSSKSDVV
                     NYVSENLKDYLQTMGYSGNDEEFIEKMTLLGVSIVTKPGKMSLHEPGTSHDGIHNLKEF
                     TF"
     CDS             complement(18740..19885)
                     /locus_tag="ctg1_2284"
                     /transl_table=11
                     /translation="MEYSNFFDDLKSNIIGQYEECKAYRILCESQGYNPSEHLRSEKDI
                     TNIPFLATTLFKKSANLFLSLLRVEPDKLDKWTLSSSTSGDPSMVGRRNSDLMQIRKFV
                     LMDDKFYDSASEYNCVFYPEPKVMREYKSVRIMDKPTESYIGNLLGIFDFSENTTFLLK
                     SCGEGFSVDMNSFEEFLKFNNERNNHLSLRGSTLLLYNAVLELKKQGKGPYNLGSRAIV
                     HTGGGGWDGKKGNISIGTKIERYQFVEEISEFLGIPQKNFRDTYSFTENTFPMDGHYSE
                     KLRSYLFHVPTWGRVIIRDVKTLEPLNKPGDRGLVQVLNAYGTSSFAGASILVDDIAEI
                     VANDSCPECKHEGMTFKIVGRVKGSEAKGCGATLDVRGKQK"
     PFAM_domain     complement(18761..19849)
                     /aSDomain="LuxE"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04443.14"
                     /description="Acyl-protein synthetase, LuxE"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2284_0113"
                     /evalue="2.40E-25"
                     /label="ctg1_2284"
                     /locus_tag="ctg1_2284"
                     /protein_end="375"
                     /protein_start="12"
                     /score="89.5"
                     /tool="antismash"
                     /translation="NIIGQYEECKAYRILCESQGYNPSEHLRSEKDITNIPFLATTLFK
                     KSANLFLSLLRVEPDKLDKWTLSSSTSGDPSMVGRRNSDLMQIRKFVLMDDKFYDSASE
                     YNCVFYPEPKVMREYKSVRIMDKPTESYIGNLLGIFDFSENTTFLLKSCGEGFSVDMNS
                     FEEFLKFNNERNNHLSLRGSTLLLYNAVLELKKQGKGPYNLGSRAIVHTGGGGWDGKKG
                     NISIGTKIERYQFVEEISEFLGIPQKNFRDTYSFTENTFPMDGHYSEKLRSYLFHVPTW
                     GRVIIRDVKTLEPLNKPGDRGLVQVLNAYGTSSFAGASILVDDIAEIVANDSCPECKHE
                     GMTFKIVGRVKGSEAKGCGATLD"
     CDS             20257..20646
                     /locus_tag="ctg1_2285"
                     /transl_table=11
                     /translation="MNRNNLLEFINQMSRVSDKYINSEKTDFDKANYTITQFNDEICCT
                     IEDTHIIQIKSLYVGTVNILNNKTNSLYVELGNEIECGQTLCTINHLKIPINIVSPTKG
                     ILTNILVKNKDIVQYGEILFEVTKK"
     PFAM_domain     20461..20631
                     /aSDomain="Biotin_lipoyl"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00364.24"
                     /description="Biotin-requiring enzyme"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2285_0114"
                     /evalue="9.70E-10"
                     /label="ctg1_2285"
                     /locus_tag="ctg1_2285"
                     /protein_end="125"
                     /protein_start="68"
                     /score="38.2"
                     /tool="antismash"
                     /translation="TNSLYVELGNEIECGQTLCTINHLKIPINIVSPTKGILTNILVKN
                     KDIVQYGEILFE"
ORIGIN
        1 tgctttaatt gctctaacac ttccgccttc ttctatggct gacttaaata ctttaaaatc
       61 tgaagtactt acagcctcac ttatatcatt gatttccata ccaaatctta aatccggttt
      121 atccgaaccg tacttttcca tagcagtttt ccaagtcatt ctctctattg gaagtttaac
      181 ctctactccc gccatttcct taaatacctt ctgtataagt ctttcattta attctattac
      241 atcatcttct tctacaaatg acatttccat atctacttgt gtaaactctg gctgcctatt
      301 agcccttaaa tcctcgtctc taaagcactt tgctatttga aaatatttat cgtatccaga
      361 aaccattaaa agctgcttaa ataactgtgg tgactgtgga agtgcataaa attttccatt
      421 ataatttctg cttggaacca aatagtccct tgcaccttct ggtgtactct tagtaagtat
      481 aggtgtctcc atttcaagga agttctcttc atccatgaaa tcccttatta tttttgtagt
      541 cttatgtctt atcttaaaaa ttttctgcat atctggtctt ctaagatcaa gatatctata
      601 tctgagtctt atattttcag cagcatcaag attttctttt atgtaaatag gtggtgtctc
      661 actttctgac aatattttta tttcttcgcc ctttagttcc accattcctg ttggcatatt
      721 tgggtttggc gattctctct tgactaaagt tccagaaact gaaatacaat attctgattt
      781 aactaaatcc gctttcataa aagcatcctt atttatttct tctccaaaaa ctacttgaag
      841 tataccttct ctatctctta aatctacgaa tactaaccct ccaagatttc tttttctctg
      901 gacccatccc atcactacaa ctctatttcc aatatggttc tctcttattt ctccacacat
      961 aatggttcgc ttcaatccat ttaaagattc tcccattttt attcctccta aaatacgtaa
     1021 tacctatgtc ataaataaac cacttcatat agtccattga agtggtctca aatttaattt
     1081 taaacctata atatactttt atcaaggttt attatccata taatgttttt aaaaaatata
     1141 ttttgccatt taccttttct tcaatcctat ttatgtactc ttttacatcc tttaaatttg
     1201 gatatctttc tattctgtta gtctctttaa atagtatctt tgaaacccca tggcacccaa
     1261 ttgcaattat tggttggcta tcctctatca tttgtatatt gtatatgcat tctttaccct
     1321 ctagagagta tcctacattc tccatatttc ctaccatgtt cttctgtcta tacatgtaat
     1381 agggcttcat attaagctct cttgcacagc tgtatgcctt ttcaaacata ttcactatat
     1441 catcttgatt tggtgcttct atccttttat cctctagcat atcctcaaat aacttggatc
     1501 ctctttttaa agatagtcca tgtattgtta aactttcagg tttaagcttc aatatttcta
     1561 tgcaagtatt attaatctta tccaaattct ctccaggaag tcctattata atgtccatgt
     1621 ttatattgtc aaagcctatt tctcttgcca tattgaatgc gtcaattacg tcttttgatg
     1681 tatgtcctcg tcccattgac ttaatggtct cgtcattcat agtttgagga tttatactta
     1741 ttctatgaac tttatacttt ttcattgtca atagtttttt ccgtgttatg ctatctggtc
     1801 ttccacactc cacagtaaat tccttaacat tattaccctc tataaagctt tcatatactg
     1861 atttcattat agtttcaaat tgttcatcgc tcacagaagt tggagtacca ccaccaaaat
     1921 atacacatcc tatttttagt cccctttgcc ttatataact tgatgttttt tctatatcgt
     1981 acatcatagc ctttaagtaa tcatccacat aacttttaca gtgactaatg gtatctgata
     2041 taaatgaaca atatctgcac cttgtaggac aaaatggcat gcctagataa atgctcacac
     2101 tattgtctac agatttcaaa aacttctttt catttttact aacttctata caaagcttag
     2161 ccttcttttc atcagtacta ttatgaacct tgaagtattc aattatttct ttatcacttt
     2221 tattttcttc caaaagctta cttgctattt tacttggtct tatacctatg agtgttcccc
     2281 atggtatatt tcttttacct gtaagtccag agaaatattt gaatacagcc atttttacat
     2341 tctcattaat attaagcctc aaatcaaatt tataattttc aggctcactt tcttttgagc
     2401 aaatttccat actctcatta ttaaatacta tgctataatc ccataatgta gattttacaa
     2461 ttttaacttc atcgaagaac aaaattgcca tatgataaac agcatacgaa tgcgcttcat
     2521 cacttatctt aattttagtc ataaaatctc ctctagtttg atttaaatga aaggattatg
     2581 aattttttca tatcctatag tagttccttc accatgtccc ggatatacaa caatgttttc
     2641 atcgagtttc ataagtttac tttttattga atttataaga gtagaaaaat cccctcctgg
     2701 aaagtctgtt ctgcctatag aactgttaaa aagcgtatct ccagaaaaca agtaattatc
     2761 cactaaatag cacattccac ccggagtatg accaggtgtt ttgatgcatt ttatttttaa
     2821 ttctccaaat tgaagttcat caccatcatc cacatacttc gtagcatttt cgcttttatc
     2881 accaaacata tattctccat tttctattaa cttgcaatca tctttattca tgtagacatc
     2941 cacattatat tcctttttta actctgccac agcagctgta tggtctgcat gtccatgagt
     3001 taatagcaca aatttaaggt tcgtctctgt atccttaaaa gcttctaaaa tagcctgtgg
     3061 tgcatcccct gggtctataa ctacactttc gttggatttt tcatcaacga gtatatagca
     3121 atttgtcata tatgctccag cctgaattac actaattttc ataatatcac ctctaaaata
     3181 cttttttact atcaataaga agagttacag gaccatcatt ttgtatatct acatccatat
     3241 gtgccccaaa tactccagtc tgaacatttg gaacttcttt tctacacaaa tcaacaaaat
     3301 cgttgtatat tttttcagac ttatctccag aaagagcctc tataaaactc ggtcttctcc
     3361 ctcttctaca atctccatat aatgtgaatt gtgaaattac aagaagttct ccattaacat
     3421 cctttaagga tttatttaat tttccctctt catcttcaaa tatccttaaa tttagtattt
     3481 tattctttaa atactctatg tcctctagag tatctccttc tgttattcca ataagtgcat
     3541 ttataccttt tcctatttgc ccaactactt taccgtcaac ctttactgaa gatttcttta
     3601 ctttttgaac gactgctctc ataaaatccc ccctagctat tagttctata tatatcaata
     3661 atgcctggaa gccttctaag ctttttcata agcagcgcta aatgctcaac atcctgtatc
     3721 tttaacttca aattgagata tgctgatccc tttgaagttt ttgcattaac cgattctatt
     3781 gctatttcca tgtaacttat aacttctacc acatccgcaa gaagagcttg cctatcttcc
     3841 gctttaattt caacttcagc catataactt tcgtttttac tttttcccca ttttacttct
     3901 atgattcttg aactatcctc tttgattaaa ttatttacat ttgtgcaatc agtcctatga
     3961 actgaaactc ctctgccttt tgtaatataa cctattatag gatcaccagg aactggtgta
     4021 cagcatttcg caaatcttac taggacatca gaaacgccct taaccgttac tccaggctgc
     4081 tcactcttag aaatcttttt agaggagtgt tctttatgaa tgttcttatt tacattttca
     4141 agtacttctt catttgtaag agaaccatta tccttattct tttcataaat atctttaaat
     4201 ctacttaata tcactgatgc ccctactgca cctattccaa cagaagcata taaatcgtct
     4261 attgagttca tattatatcg ttttaatact aactctaaat tttcaccctt agctatctct
     4321 ccaaaattaa attcctgctt tttcgattct ttttctaaga gttctttgcc cttgcttatg
     4381 ttttcatctc ttttagcctt tttaaaccaa gaccttattt tgcttttagc ctgattgcta
     4441 gtaacagaat taagccaatt aatattcgga cctttaacta aagatgttgt tagtatatca
     4501 actatttctc ctgttttaag cttataatca agtggaacta ttttaccatt aacctttgca
     4561 cccacacacc tatttcctat atctgtatgt attttataag caaagtctac tggtgttgca
     4621 ttatacggca aatttattac cttaccttta ggtgtaaaaa caaaaatttc atctgaaaat
     4681 aaatctatct taaagttttc catgaactct tgagcacttg gcgtttctct ttgccattca
     4741 agcatctctc ttatccatgt aagcttagta tcatctttat ttgcattctt attttgagga
     4801 acattttgag tactttctat tgttccttcc ttatatttcc aatgagcagc tattccatat
     4861 tcagctgtct tatgcatgtc ataagttcta atctgaatct caaaaggctt tccctcaggt
     4921 cctattaccg tagaatgaag tgattgatac atattaggtt ttggcatagc tatataatct
     4981 ttaaatctgc ctggtatagg tttatacatt gtatgcacta ttccaagggc agcataacac
     5041 tcttttatgt tatttactag tattctaaca gctgttaaat caaaaatctg atctaagctt
     5101 ttactcttat ttaacatctt tctatatata ctataaaaat gttttggcct tccatcaata
     5161 tctggagtta tccctgatgc ttccaaatta agtttaagtt cttctactat cttgcttatg
     5221 tattcttctc tttcaactct tttttcagct attagatcca caagctcata gtattccttt
     5281 ggtttcaaat atctgaagga caaatcttca agttcccatt ttatcttaga cataccaagt
     5341 ctatgtgcaa gtggagcata tatatccaga gtctcctttg ccttctcttt ttgtttttgc
     5401 tcacgtttaa atttaagagt acgcatatta tgaagtctat ctgcaagttt tattaaaata
     5461 actcttatat ccttagccat tgcaagaagc atctttctta cattatcagc ttgctgctct
     5521 tccttcgtct tataagttat tttatctagc tttgttaccc ctgatactaa atcagcaact
     5581 tctttgctaa acatttctgt aatatcatca tagctataac ttgtgtcctc tataacatca
     5641 tggagtattc ctgcaactat agtactcata tccataccca tctctgctaa aatacacgct
     5701 acatcgagag gatgacttat gtaaggttct ccggactccc tcatttgatg tttatgagcc
     5761 tcatatgcaa aattgtaagc tttaatgaca atatctttat ctacattatt acaattttca
     5821 tctatctttt ctaataaatc tgataattca gccattatgg tactctccta aaatcaaagg
     5881 ctggtcacat aaccagccaa atttattatt atttattata tagtatacat tttaatttta
     5941 taattgtaaa gagattagac ttttgtttac tttttacaat aatttttatc tatacattgt
     6001 acttaactaa tgacattgta tcataatctc caagcttatc ttttccattc aaatctgtaa
     6061 gctctacaac aaaacatgcc gctacaacct ctccaccaag agcttctaca agttttgcaa
     6121 ctgagttaat cgtaccacct gttgcaagaa gatcatcaac tattgcaact ctttggccct
     6181 ttttaattgc atccttgtgc atttccaaaa tatcttctcc atactcaagc tcgtatgtaa
     6241 cctcaactgt ctcacatgga agcttacctt tttttctaac tggtataaaa cccgctccta
     6301 ttttgtaagc tacaggagct ccgaataaaa atcctcttgc ttcgggtgca actattaaat
     6361 ctacgttctt atccttaaga tactctccaa tcttatctac ggaatattta tatgcttctt
     6421 tatcttgaat aagggtagta acatccttga agcttattcc ttcttttgga aacccatcta
     6481 taactcttat actatctttt aaatccattt aaatttcccc ctaaaatata tttagaaaat
     6541 actaacttaa cttatatgta atattgaaaa ccctataaaa taattatata tcaattattt
     6601 tacattttac aatacactaa aaaaaatcac ctttatatct aaactcatta tttagatact
     6661 tggctatttg ctctgcttta taactgtcct ctgttgtaaa aagttgaact attattctcg
     6721 cattatccat cttacccacg gcatttacag taggtacaac agcttcagat aacttcctta
     6781 cctcatctat atcaactttc tcgacagatt ttaattttag caaagcttct attccataat
     6841 tattggtatt ttgtattttt cttataccct gatcaactat aattttattt tctcctgata
     6901 actcttcaca tttatgtata gtaccaattg ctgcaagatc taaatattta ttaacgcatt
     6961 tcatttgata atacattgaa atagcttcac atagtttaaa tactattcca gaaacacaaa
     7021 attcgttaaa cggatactta gattccttcc tattaggatt tactactatt gcataatcct
     7081 cttcattgca catttcatga taatcaacta ctattgtatc tattttaagc ttttttaata
     7141 atgcggtact ttcttttgaa ttaattccac atcctattgt tataagcaaa tttgctccaa
     7201 agtattttat tttatcattt acataatcag catttacttc atagctacca caaaaatcat
     7261 cgggtataag gtattctaca tcagcattaa ggtatttcaa aaccaataac attatggaca
     7321 tacctattat actgtccaca tcgcaataac catataacac tattttctct ctattgttta
     7381 tagcctttgc tattctctgt agtgcttcat tcattccttc aattaagaat ggattatgca
     7441 ttccctttaa tccgaaatat tgtaacttat ctcccgttct ttccatcttt attcctccga
     7501 atttgtagaa aacaaatata ttataatgta ttatgagata ttttacaaat acttttttag
     7561 ctaaaaaaat aaaacagccc ataggctgtt ttatttttga gcttctgctt taatttggag
     7621 cttttttttg ttagctcttt ccttaaatat aacccataat ggactagcta taaatattga
     7681 agaatagcat ccagaaacta taccaacaag taaaggcttt gtaaaatctc ttacagatgg
     7741 aacgaataca tgtactgaag agactgctat taaaacagtt agaaccgtat aaattgatct
     7801 tgtcaaagtt tcatttatac taaaatcagc aatttcagat gtactcattc ttctatgctt
     7861 cctgctattt tctcttattc tatcaaaaac aactatagta tcactcatag aatatcctac
     7921 tattgttagc attccagcta taaatggtga atttaatggt attgcaaaaa tcccatatac
     7981 cgcaagtgtt acaagtacat catgaactaa cgatatcata gctgctacac caaatttaaa
     8041 ttcaaatctc caagctatgt acaaaagtat aattaccagt gcaattgcaa gtgcaatcaa
     8101 cgcttttgtt ttaagttcct gtcctatagt tcctcctatc ttctcttgag aaaccaaggc
     8161 ctttgatttt aaattatatt ttttttgcat atccttaaat attttgttac caatagcatc
     8221 tgtcatggta ctacttttta tttcaacctc agtattatta accgtggtta tagtactatc
     8281 ttttatatat ttatctacta tcttttcaac atcagttttg ttaaaggact tccctatctt
     8341 tatatccatt gagtttcctc caacaaaatc tataccaaat tccaaaggtt ttcctgtagt
     8401 aactcctcta tatatcatga atgcaattcc taaaaatatt atagtaagag atataccaaa
     8461 ccaaacttta gtatgtttaa taaccttaag cattacttac cactcccttc cagattaact
     8521 ccgaaatgag atgctttatt tataagtccc atgtctatag cccacatcaa aagtcttcta
     8581 gttacaataa tagcagtaac catacttata agaacaccaa ttaccagtgt taacgcaaat
     8641 ccttttacct cgccacttcc aagagcataa agtataacac ctgaaataat agtggtaaca
     8701 tttgaatcta ttattgatga catagcccta tgaaaacctg catcaaaagc tgatctaact
     8761 gttttaccaa ttttaagttc ttctttaaat ctttcaaata taagaacatt ggcatctaca
     8821 gccataccta tcgtaagtaa aagtccagct atacctgaaa gtgttaatgt aacttttaca
     8881 gctacaaatg cacctaaaac caaaacagta aataaaacta gtgctatatc tgccataaga
     8941 ccaggtattc tatatactaa aatcatgaat aagaatatta tacatatagc aactgctcct
     9001 gcaagtatac tgtttggaag tgcacttgca ccaagtgagg cacctacagt tttggattga
     9061 acaactttta gtgttacagg aagagctcct gagtttatta tattagctat acgctgtgct
     9121 tcttgaatag atttattacc agttatctgt gcatttccac ctgttattac tgaatcaaca
     9181 gttggatcac ttaaaagatc agtatccata tatatagata tcttttgtcc taagaacttt
     9241 tgtgttgcat cagcaaattt ctttgttcct gaactattta attgaagtga tataataggc
     9301 tgattagtat ttggatcagt acctgctgtt gcctttttta catcgcttcc agttaaaact
     9361 gttttcttat caggacctac gaacttaagt ttaccagttt tacctatttt atttataact
     9421 tcgtctttat tgtacattcc agggacatca atttcaattt tattgtttcc cactcttgat
     9481 acagttgttt cactaactcc taacttatta actcttaaat ttagaagttc tatagtccta
     9541 cccattgcat cactatttac cttaccttgt atttcttcta ctacagaaac accaccttga
     9601 agatcaagac ctttatctat tgattctgta aaggatttaa ttctgtaatc ccccacatta
     9661 agtccagtac tgcctaaata ggctaatcct gctattataa gaacgcttat aataaagaag
     9721 atggtgcttc tacccttctt tttcattttt atcccccttc atcaccaaat tatgccatat
     9781 aatttatatt gtaaaactta ttctttaatt ttgcaataac aattttctct tattttaaaa
     9841 gttttatgcc aaaaaagccc aaacgtaaac catatggttt aatttagcgt ctattttttt
     9901 agtaaatatt agttctttct tcctctaagc atattttact atactttttt attataaata
     9961 cgggatttaa atctcgtcaa caaaatctaa tattttaaat ttaatctacc atctgtgctt
    10021 ttaatgcaat agcacactct attctctttt tttgcatttt acatcctatt tcatacggaa
    10081 tatgcatatc tccattaaaa ttataattat tagcctgaca tccaccactg cagtaaaatc
    10141 tagcccaaca ttctctacat ttaggcttat tgtatatatg tgcctctcta aattcattac
    10201 ccatttcttt attaatattg tcatcatcat atatagttcc cattttgaaa tcttcgtttc
    10261 caacaaattg atgacatggg tatacatcac ctgatggcgt tatagataca tattcatgtc
    10321 ctgcaccaca tcccgaaatc cttttgtata cgcatggtcc accatttata tcaatattaa
    10381 aatgatagaa tttaatttct tttccttctt tatgtctctt tatcatatct ttatacaatt
    10441 tgtcgtattg ctcaaatatt tgtggtatat cttcttccct taatgaaaga ttatgatcat
    10501 ctggcaacac tacaggttca atggatatct ctttaaagcc catatccgca atatacttta
    10561 cgtcttcaaa gaaatcagta ttatttcttg taaatgttcc tcttacataa tactgttttg
    10621 atttgtctct tctagctacc attttcttta tattcttaag tatagcatca tgtgatccag
    10681 ttccatctgc tcgtactctt accttatcat taacttcttt tcttccatca aagctaagaa
    10741 ttatattgcc catattttta tctaaataat ccattatttc atcatttaaa agtgttgcat
    10801 ttgtagtcat tgtaaatctt atatttttat tgtatttttt ttcttctttc ttggcatatt
    10861 caacaacctg ctttattgta tcaaatgcca taagaggttc tcctccaaat aaatccactt
    10921 caatgttttt acgaggtcca ctatgtttta tgacgaaatc aattgacttt ttagcaactt
    10981 caggagacat tatttctctg cagcctttat attctccctc atccgcaaaa caatacttgc
    11041 actttaaatt gcaatcatgt gctatattta aacataaagc ctttataaat gatggagatt
    11101 tagtactttc tttagctata tcctcatata aatctttaga ataaagaact ccctcatcaa
    11161 taagttcctt tatttcatca tatgcttctg aaatttcttc ttccttgtat ttattcttca
    11221 atctatctaa tagttttttc ttacttctta ttttatcctc atcaattaaa tcataaacca
    11281 tctcatctac ttcatgtatt gaaccagaat taacgtctat tatatatctt tgatcatctt
    11341 gaatgaactt atgcactaat gacaaaattt tttcctcctt aaaatcaact tctaattttt
    11401 attattataa cttcacaaaa agtttagggc tgtcccaaaa tattcaacta ataaggaagg
    11461 gtttaacctt gctatcgtta aaactaagga ttttcttcgt gaaaaatttt ttcataactt
    11521 ttcctctcaa aaatcttagt ttttaacgag taaagcaaag ttaaacccct agtccccgtt
    11581 ctcaccttaa aggtgactgt tacctgattt tttatattat ttactttcgc aagctaaatt
    11641 tgcaactgtg caagatgtct tacatgctga ttggcatgaa tttgcacatt ccttacatcc
    11701 aggtttttta agactttctt ttatatttga tttattaata ctttttatat gtttcattat
    11761 gattcctccc atttaataca agctacaata aattatagca taatttaaaa attaaataaa
    11821 gaatttaaat gttaattcca agcattcctg acaatatacc aactacaatt gccaaagtaa
    11881 ctcttataaa atctctcaat tgcatacctc cacttgatcc atctacaaga gaaacaatat
    11941 aaaatatcaa gatataaaac aatccaacta aaagtccatt aagccagccc tttttgccag
    12001 attttcttga ggaatagata ctgccataca ttacacttaa aagagtagtt actagtataa
    12061 ccatattagt aataccttct gaaaaactga ttttagtaga aacaaaagaa aaaatcaaaa
    12121 taacaataag agtaacaaat attgccctta aaactcctcc tgctgccgaa acgtaaattt
    12181 tactactttt ctccaaataa actcaccccc atccacacaa aaaacaattt catacaataa
    12241 ccgtacaatt attatttatg tagacagaag tagttttatt acactctact tttgattatc
    12301 tgcttttctc gtttcaactg ttgctattgc ttcttttttt atttttattt taactttatc
    12361 aggtcctgtt tgaataatga caaattgttc ttgtatgtta gttatctgtc ccattattcc
    12421 cccagttgta acaaccttat catttactct catctctgaa agcattttat taaacttctt
    12481 ctttttagct ctatccggta tatacatagc aacataaaac attccaagta aaaatacaac
    12541 ataaagtatc gttaaaactg tatttggcat aataaagtat cactccctat aatattgaat
    12601 ttttaagctt ttccagccca tgcttttaat ttctcatttt taaattcttc aaaacaatct
    12661 gcatctattg cattacgtat atcttccata agtgtattat agaaataaag attatggagt
    12721 acacataagc gcatagcaag catctctttt gctttaaata aatgtcttat ataagctcta
    12781 ctatagtgct tacatgttgg acattgacat ccttcatcta tcggagaagc atctaattca
    12841 aacttttcat ttcttagatt tatcttaccg tgtttagtaa atacatgtcc atgccttcca
    12901 tttctagcag gtagaacaca atcaaaaaag tccactcctc ttgaaactgc ttcaagtata
    12961 ttacttggag tcccaactcc cattaagtat ataggcttat cttgtggcaa atgtggaaca
    13021 actgcatcta ttatgcggta catctcttca tgagtttctc ctactgcaag cccacctatt
    13081 gcatagccat ctaaatccat tttagctata gtttttgcat gctctattct tatgtcatca
    13141 taaactcctc cctgatttat accaaaaagc atttgctttt tatttattgt atcaggaagc
    13201 gaatttaacc tgtctaactc ttccttacat cttacaagcc atctagtagt tctctcaacg
    13261 gatctttcaa catattctct cggagatggg ttctcaacac attcatcaaa agccatagca
    13321 atagtagacg caagattact ttgtatcttc atactttctt ctggtcccat aaatatcttt
    13381 cttccatcaa tatgcgaatt gaaataaact ccttcctctt tgatttttct tatttctgcc
    13441 aaagaaaaaa cttgaaatcc accagaatct gttaaaatag gcctatccca attcataaat
    13501 ttatgaagac cacctaattt ttttactacg tcatcacctg gacgaagact tagatgatat
    13561 gtatttgaaa gctcaacttg acaatttatt tccttaagat ccatggagga cactgcgcct
    13621 tttatagctg caagcgtacc aacattcata aatacaggag tttctattgt tccatgaaca
    13681 gtctcaaatc gtcctcttct gactttacca gttttcttta aaagtgtgta caaatgtatt
    13741 cctcctcagt ttattttata aacatagcat ccccaaagct aaagaatcta tatctatttt
    13801 ctacagctat tttatacgca ttcagtatat tatctcttga agataatgca ctgacaagca
    13861 tcactaatgt tgactttgga agatggaaat ttgttataag cccatctact atcttgtatt
    13921 tatatccagg atatatgtat atatcagtcc acccagactg ttctctaaca tttccttttt
    13981 catctgcaat agtctccaag gttctagttg aagttgttcc aacagatata attcttccac
    14041 cattttttct agtttcattt atagtatcag cactctcttt tgaaagcata taatactccg
    14101 aatgcatatg gtgactttct atattttcta cctttacagg cctaaatgta ccaagaccaa
    14161 catgaagagt taaaaataca gtttttattc ccttagctct tattttatct aatagctcat
    14221 ttgtaaaatg caaccctgct gtaggtgctg ctgcagatcc attatttttt gagtatacag
    14281 tctgatactc ttctttattt tctaattctt ctgttatata cggtgggagt ggcatttgcc
    14341 caagcttatc aagtatttct tcaaaaatcc cttcatactt aaattccaca actctattgc
    14401 cgtcttctcc tatactctta attactgcct ttaaaactcc accaccaaac tcaaactcgg
    14461 ctccaacttt tgctcgctta cctggtttaa caagagtttc ccacgtatct ttatcaattc
    14521 tctttagaag taaaaactcc atctttccgc ctgttcctac cttatttcca ataagtcttg
    14581 caggcaaaac tcttgtatca tttagtacaa ggcaatctcc tggatttaaa taatctatta
    14641 catctttaaa aattctatgc tctacttctc cacttttttt atctactacc ataagcctac
    14701 actcatctct tttatcacaa ggatgctgag ctataagttc ttctggtaag taataatcaa
    14761 aatcttctaa ctgcaaaata tccacattcc tttcatttac ctacttaaaa tcttactttt
    14821 cctttttaaa aaatgagcat tgatcattat ttacagtacc attttttttc atattaaatg
    14881 gcacttttaa atgttcatat gcttttttag ttgccattct acctctaggg gtcctcatta
    14941 taaatccctt ttgaagaaga taaggttcat atacatcttc tatagtatct atctcttctc
    15001 caacaaaata agacaaagtt tcaatgccta caggtcctcc agcaaaatta ttaactattg
    15061 cctgtattat tttattatct atgctatcaa aaccttcatc atcaacttca agtaaattaa
    15121 gggccttttt agcagaatca agattaacta tacctctccc ctttacatct gcataatccc
    15181 taacccgctt aagaagccta tttgcaattc taggagtacc tcttgatctc attgcaattt
    15241 cgagagctgc atcttcatcg atatcaatat caagtataga tgatgatctt actattattt
    15301 ccttaagttc ttcatcatta taaaactcca tagggcaaag aacaccaaat ctatccctta
    15361 agggtgcagt taataatcct accctagttg tagctcctat aagagtaaat ttaggcaaat
    15421 caagtcttat agattttgcg gcagctcctt tacctattat tatatccaaa gcatagtctt
    15481 ccattgcagg gtataatatt tcttcaacac ttctgttaag cctatgtatt tcatctataa
    15541 atagtacatc atactcagaa agtcctgtta aaatagcggc taaatcccct gctctttcaa
    15601 tagctggtcc agatgtaact tttaaatttc cacccatttc cttagctatt atatttgcaa
    15661 gagtagtttt tccaagacct ggaggcccat aaaaaagtac gtgatcaaga gcctcacctc
    15721 tctttttagc tgcccttata aatatatcca ttttttcttt tactttactt tgacctatat
    15781 attcatttaa cttttgaggc cttaagttat attctgcaga atcttcttct aaatttactg
    15841 atgttaaaat tctatcatcc atattaaatc actctcaatt cattaaaaac cttaaacaac
    15901 tttttataat attttcaatg ccttcactct tgtccacatt atttatagcc ctatctgttt
    15961 ctttttctga gtatccaagc gaatttaatg caaatcttac ttcttctagc ttcttactgt
    16021 gttcatcata atccacatct aaattattaa tttcagaatt tccctttgaa atatctgtag
    16081 acttaaattt atcttttaac tccagtatta tcctttgcgc agtcttttta cctattccag
    16141 gagcctttac tatggtcttt tcatcacctg taattatagc atattttaaa ttatttacag
    16201 tacaaatgga caatagtgac aaagaagctt ttgccccaac tccatttatg gtaagaagtt
    16261 tattgaacat ttcaagttca tctttagtca agaaaccata aagacctata aaatcctgtc
    16321 ttactatttg agttaaatat atgagaacat cttcttccgg cttaggcata ttagccatag
    16381 tattacctga tgtaaaaatc ttgtatccca caccattatt atctactatt atgtaatcct
    16441 tatttattcc tatatacttt ccctttatgt attcatacaa aatcgttacc cccaagtaaa
    16501 atattatcat tttaaaaata aaacctacag gtcgtttaat cataacctgc aagtttctta
    16561 gcatcttctt ttgatccaaa aaccaaaaat ccttttctta aaagatccct agtttcattt
    16621 ttgagctgat ttacacttat ataagcctgc tcattagttt ttataaggct tccattgtca
    16681 tctaccttat atacatttat tttatcacta tttttgtctt tatttaagat aaatacacca
    16741 tcaactttat gattgtttat atatctattt tttatgacct cgactttcat atcattgtcc
    16801 catattacaa tatatccttg tttctcataa cttctagtta tttgttcttt agtcattcct
    16861 gctttatgct ctttttctgc attagtttct tcacttgatg ttaaaacatt attctttgtc
    16921 tcatcttctg gatcaaaggt tatatcataa ttttgtttta ctatcaaaag ggccaaggtc
    16981 ttttttccct ctttattatt tgaagtgtat ctagctttct cactttcatt tcgtcccaaa
    17041 aattcatcaa tgcctttgga tattttatat ttttctgcat tcataatctt aattaagttt
    17101 cctctatacc ctatgcaaaa tgaaaaaata aaagttacta ataaagccac aacacttaaa
    17161 ataactttct ttttcagtgt catactatcc ctcctattta tattggatag tattaacact
    17221 tttaatattt tttattcaaa attaactata taaaatatgc taccaactat tatatatcaa
    17281 ctatttatat aattgcaaat taattatagg atttctcaac ctttaaacag ctaagaaatc
    17341 ctataaaaaa attagttaat atttatatta tgacctatac ttatatttta gatttgtcta
    17401 ctaaccaaaa atgtaaactc cttaagattg tgtattccgt catgagaagt tcccggctca
    17461 tgtaaagaca tctttccagg tttagttact atgctaacac caagtaaagt cattttttct
    17521 atgaattctt cgtcattgcc gctatatccc atagtctgaa gataatcctt taagttttca
    17581 gagacgtaat ttacaacatc gcttttactt gaataaggac atacaaatat aaatctataa
    17641 aaacatttgt ttatatcttc tttttcaggc attccatctg atagaattac tgtataatca
    17701 gcattgaagg aagaataaac tttaaatctt ctttcatttt tcattccata tttaagagta
    17761 cagtattgtc tgtcttgtat tgtcttaact gaattccatt cacttaaata tgccttaggt
    17821 ataacctctg tgatttttct aagagaagcc gaaagacaat gtgaaaattc atctacatct
    17881 atcttatcat ttagaaatac taccctaggt gataaacaag ccttctgttc ccaacatatt
    17941 atatcctttg ctatctcctc tgatacttta tttaagtcat cacatttatc aactacttca
    18001 aaacttattt ttgctccatg cattatcatg tgtttttgat actttgcgca catttcacct
    18061 attattcttg aagaatactc tccaccccag tgtataacac catctgaatt tttaacgatt
    18121 gtgtcataga tttcagtttt actactatca aagtacaaaa cggatagcct atctttcaca
    18181 gtttcatcta actcacatag acttttataa aatgcatacg caaaatatgg ttcatcttta
    18241 gataccttaa ctaaattaca gttttttgac aaaagaccca tggatatgct cattggtata
    18301 accacgaaag catttcctga aatattatga aatataatcc ctcttggctg tctatgctca
    18361 tagccataat ttgttttgtg ccatgaatct aaaatatcta cctctccaag ttccctctta
    18421 atagtatttt gtatattttc acgaagaagc atttgcatca tactcttaaa ctcataattt
    18481 actaattcaa aactttggtt tgttatctgt gctaatgttt caatatgctt ttttgaataa
    18541 ttgtcatcaa gccataattt tgcacatcta tcaagcaagt caattgtttc ctcggttttt
    18601 atatcatgaa ctttattttt attcttttta agcctttcta attccttctc tacatcacct
    18661 ttaccgcttg tcataagttc aagctttaat ttattaactt ccttaatagt tatctcttcg
    18721 ccacatgtaa attcaagctt catttttgtt tcccccttac atctaaagta gctccgcatc
    18781 cttttgcttc tgatccttta actcttccaa ctatcttaaa tgtcattcct tcatgcttac
    18841 attcagggca agaatcatta gctactattt ctgcaatatc atccacaagt atagatgctc
    18901 cagcaaaaga agatgttcca taagcattca aaacctgtac aagtcctcta tcaccaggtt
    18961 tatttagtgg ctctaaagtt ttcacatctc ttattattac tcttccccat gttggaacat
    19021 gaaataaata acttctaagc ttttctgaat aatgtccgtc cattggaaat gtgttttctg
    19081 taaatgaata agtatcacgg aaattttttt gaggtatgcc tagaaactct gaaatttcct
    19141 caacgaattg atatctttct attttagttc caatagatat atttcctttt tttccatccc
    19201 agcctccacc gccagtatgt actatcgctc tacttcctaa gttatacgga ccttttcctt
    19261 gttttttcaa ttccaaaacg gcattatata aaagaagcgt tgatcctcta agtgataaat
    19321 gattatttct ctcgttatta aactttagaa attcttcaaa ggaattcata tcaactgaga
    19381 agccttcacc gcaagacttt aacaagaaag tagtattttc actaaaatca aaaataccta
    19441 ataagtttcc tatataagac tctgttggct tgtccattat acgaacactt ttatattctc
    19501 tcattacttt tggttcagga taaaatacac aattatattc acttgcagaa tcatagaatt
    19561 tatcatccat taatacaaat ttccttattt gcattaaatc agagtttctt ctgccaacca
    19621 tactaggatc cccacttgta ctacttgata aagtccattt atctaattta tcaggttcta
    19681 ctctaagaag actcaaaaac aagtttgcag attttttaaa aagagtagtt gccaaaaaag
    19741 gaatgtttgt tatatccttt tcacttctta agtgttcact tggattatat ccttgacttt
    19801 cacacaatat cctataggcc ttacactctt catattgacc aataatatta ctttttaagt
    19861 catcaaaaaa attcgaatat tccatattat gtcacctcac atattttaca tttattatat
    19921 ttttttctat attataatta taattcaaaa aaattctatt acaaattagg atatatactg
    19981 tatttatcat tatagcttct taattttaag tatgaccagt cagtctagtt ttttcttaaa
    20041 attcattgat tttcctttaa taagtcttaa aactataaat aaaattatat aacattaaaa
    20101 ttttaatgca ttaatgttcc aatatcaata cctatattta gaattaattt aaaatgtagg
    20161 catattattt aattctaata aatggtataa ttatattatt atagaaactt tgtattaata
    20221 ttatagaaag gagaagtttt aaattaaaat aagcatatga atagaaataa cttattagaa
    20281 ttcattaatc aaatgtcaag agtatctgat aaatacataa attccgaaaa aacagacttt
    20341 gataaagcaa attatactat tacgcaattt aatgatgaaa tttgctgtac tattgaggat
    20401 actcacatta tacaaatcaa atctctgtat gttggtaccg taaatatact aaataataaa
    20461 acaaattccc tgtatgttga acttggaaat gagattgagt gcggccaaac cttatgcacc
    20521 attaatcatt taaaaatacc tataaatatt gtttcaccaa ctaaaggcat acttaccaat
    20581 atacttgtaa aaaataaaga tattgttcaa tatggtgaaa tacttttcga agttaccaaa
    20641 aaatagacta tacatattat atttttttac tttaataaat aagaatggca cctgtataaa
    20701 agcgccattc ttatttatta aattctattt ttcaataatt attatcttca tagcttcaat
    20761 tctcaaactt ttaccgacag tccctgctgt ctccccatcc ttaacccagt tttgccatcc
    20821 ttggttttgg acttcagctt gatacaaaat actgtattta tcagctccag ttccttctag
    20881 cattatctgt agagactcta ttcttaatcc ttttccttct gttcccgtta gagctccatt
    20941 ataaatccag tcttgccacc ctatattttg cacttgagtt ttatatttta tgtttaaacc
    21001 taccggtgtg ttatttaagt ttattttaag tgcctctact cttaaccctt gtccttccgt
    21061 tcccgaaact gctccatctt gaacatagtt ctgccacccc acattttgta catgactctg
    21121 ataagatacc ataggtggtt tttcagtaat tttaattttt atagcctcga ttctttctga
    21181 ttttccaaca gttccagctg tctgaccatc cctaaaccaa ggctgccagc cttcattctg
    21241 tacatgaacc tcatactcca cactatattt atctgcatcc gttccctcta gcattatttg
    21301 aatagcctca actcttagcc cttgtccttc tgttcctgct agagctccat tatataccca
    21361 actctgccaa cctatatttt gtacttgagt tttgtatttt atatttaaac ccgccggcgc
    21421 gttatttaag tttattttaa aagcctccac tcttaatcct tgcccttctg ttcctgctag
    21481 agctccatct ttgacataat tttgccaacc tatattctgc acgtgtgctt catatataac
    21541 tgatggagtg gctactgcca aattctgacc aattccaact gtatcaaaag cattattcac
    21601 agctgcaacc tccgctgaac cacctccata caaatctaca gcggactcta ctaaaacatt
    21661 tcgagcttca ttaaaatcag tagtgggagt catataattc actaatgccc tgtaatatat
    21721 tcttgctgtc ttttccatac caatactttg tgcaata
//
