LOCUS       NC_015687.1            20763 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_015687.1 Clostridium acetobutylicum DSM 1731, complete sequence.
ACCESSION   NC_015687
VERSION     NC_015687.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 15:30:49
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 76727
            Orig. end    :: 97490
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..20763
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[86727:87490]"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10763
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..20763
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..20763
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="1"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             571..1269
                     /gene_functions="transport (smcogs) SMCOG1243:ABC
                     transporter, permease component (Score: 176.6; E-value:
                     1.5e-53)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_68"
                     /transl_table=11
                     /translation="MTFSEIAYKMFKKDAKKYRLFILCNVAAIAVLYSFISIVLNKQFM
                     NSSIVDPMISSNIYAPTFFIVMFAGMFIPYSQSVFMKARQKDYGILLSIGMTENEVRKS
                     VIIENLVLHAVSLVAGLMFGTILSLFFLGFIHSIIGISNINVTVSVVSYEMVTVCELIL
                     FIISLIVNCYSMVKSTIYAKIKHTEKTESTGRYSIKFIFIGLVITIAGLILVAFFYENN
                     DNIGLMGLLI"
     CDS             1285..2484
                     /locus_tag="ctg1_69"
                     /transl_table=11
                     /translation="LIFFNGEALIGCFEGRNYKKYIRNIFLFSDMKYYYGKNKKVFLVS
                     SWLIFVVMFFSALSFINYPSSIKYAYTYHPFHMAYGDIKDGLKPLDDNEVASIVHKNNN
                     SITRSNTVKFLRNRVFTVFSVNDVNRTLKTNYRVKPNLFIYVHPYDINDGYKREDINIR
                     IPSIDINSDDGVRKFKVQDTIIKPLFGQINCISNNIILVNEDDYNWIALNGTDYVFKGT
                     LHLYNFASWRNSNPIVNEVRKRLLKGNNRSKEDAFYKISSKVEAYNTSLKSCNFLIFNL
                     IYICVLLYFSVFIMIHYKLMMEYKDDQMRYFSLYKIGIDEIEIKRIVKQKILMTYFIPF
                     IYAVIINIPFSYYVFNSHIHSGLENPIIITTSIAFFIIHLVMCKLYTNVYYKRIISELP
                     "
     CDS             2678..3067
                     /locus_tag="ctg1_70"
                     /transl_table=11
                     /translation="MFVWKDEFELGIDKIDNEHRKLFEIANKGYELLKNEFYVDKYDKI
                     MDIIVELKEYAEFHFSEEEDYLASIGYKKLFTHKLEHDSFIKKVESFNIKEIDYDQDKY
                     IQEMLDFVVTWIKEHILEKDREYID"
     aSDomain        2687..3061
                     /aSDomain="TIGR02481"
                     /aSTool="tigrfam"
                     /description="hemeryth_dom: hemerythrin-like metal-binding
                     domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_70_0001"
                     /evalue="4.50E-31"
                     /identifier="TIGR02481"
                     /label="ctg1_70"
                     /locus_tag="ctg1_70"
                     /protein_end="128"
                     /protein_start="3"
                     /score="105.5"
                     /tool="antismash"
                     /translation="WKDEFELGIDKIDNEHRKLFEIANKGYELLKNEFYVDKYDKIMDI
                     IVELKEYAEFHFSEEEDYLASIGYKKLFTHKLEHDSFIKKVESFNIKEIDYDQDKYIQE
                     MLDFVVTWIKEHILEKDREYI"
     PFAM_domain     2708..3058
                     /aSDomain="Hemerythrin"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01814.25"
                     /description="Hemerythrin HHE cation binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_70_0001"
                     /evalue="2.40E-09"
                     /label="ctg1_70"
                     /locus_tag="ctg1_70"
                     /protein_end="127"
                     /protein_start="10"
                     /score="38.0"
                     /tool="antismash"
                     /translation="GIDKIDNEHRKLFEIANKGYELLKNEFYVDKYDKIMDIIVELKEY
                     AEFHFSEEEDYLASIGYKKLFTHKLEHDSFIKKVESFNIKEIDYDQDKYIQEMLDFVVT
                     WIKEHILEKDREY"
     CDS             complement(3127..4095)
                     /locus_tag="ctg1_71"
                     /transl_table=11
                     /translation="MNKKILLTTLIGASIFIMAGCSNSQSNDQSKTPSKQSKVSTAKAP
                     NTSTAKDPKQSENINSSSENNTKSTSKTTNSNTPNNKATSSTPAPTNKPSSMYSIAQNT
                     YTIANIKINYPQISNLGDNNKQLAINNLIKDSVINGFNLTQAIKTKTLPNYNEPIENLT
                     LNVNYTVELQNSNILSIRYLGSSNMKGSAHPNNELYTTNIDINNAKTMNLQGMFSINQT
                     LINTFRKGAYIPYNSSIDSQTISKEISTYNDSYLQTAFEKSDNPIGQENPSSAFSYLTK
                     DGLVISIGITHAAGDHAELKIPYSSIKSIVKTDNKALNGLF"
     PFAM_domain     complement(3511..3774)
                     /aSDomain="PdaC"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13739.8"
                     /description="Deacetylase PdaC"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_71_0002"
                     /evalue="6.20E-10"
                     /label="ctg1_71"
                     /locus_tag="ctg1_71"
                     /protein_end="195"
                     /protein_start="107"
                     /score="40.1"
                     /tool="antismash"
                     /translation="ANIKINYPQISNLGDNNKQLAINNLIKDSVINGFNLTQAIKTKTL
                     PNYNEPIENLTLNVNYTVELQNSNILSIRYLGSSNMKGSAHPN"
     CDS             4293..5012
                     /locus_tag="ctg1_72"
                     /transl_table=11
                     /translation="MQNVFNVNQKIGDIVVKFPRAIEILKRYKIDFCCGGDRVLEEAIK
                     EQGLNGQEIIDEINEDYNKYIMEEVKDRDWATEPYSKLIEHVINTHHAYLNETLPRLSE
                     LTTKILRVHGAKHSELAKVHKLLHSLKMELEQHLIKEEEIVFPLIQEYERTGNNETLSN
                     AVEKIIELEEEHEGAGSILKELREVTKNYELPEDACNSYKAAYKLLEDVEDDTFRHIHL
                     ENNIMFPRLVSESKKHK"
     PFAM_domain     4314..4472
                     /aSDomain="ScdA_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04405.16"
                     /description="Domain of Unknown function (DUF542)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_72_0003"
                     /evalue="2.50E-21"
                     /label="ctg1_72"
                     /locus_tag="ctg1_72"
                     /protein_end="60"
                     /protein_start="7"
                     /score="75.2"
                     /tool="antismash"
                     /translation="NQKIGDIVVKFPRAIEILKRYKIDFCCGGDRVLEEAIKEQGLNGQ
                     EIIDEINE"
     aSDomain        4323..4982
                     /aSDomain="TIGR03652"
                     /aSTool="tigrfam"
                     /description="FeS_repair_RIC: iron-sulfur cluster repair
                     di-iron protein"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_72_0002"
                     /evalue="1.40E-82"
                     /identifier="TIGR03652"
                     /label="ctg1_72"
                     /locus_tag="ctg1_72"
                     /protein_end="230"
                     /protein_start="10"
                     /score="274.7"
                     /tool="antismash"
                     /translation="IGDIVVKFPRAIEILKRYKIDFCCGGDRVLEEAIKEQGLNGQEII
                     DEINEDYNKYIMEEVKDRDWATEPYSKLIEHVINTHHAYLNETLPRLSELTTKILRVHG
                     AKHSELAKVHKLLHSLKMELEQHLIKEEEIVFPLIQEYERTGNNETLSNAVEKIIELEE
                     EHEGAGSILKELREVTKNYELPEDACNSYKAAYKLLEDVEDDTFRHIHLENNIMFPR"
     PFAM_domain     4548..4985
                     /aSDomain="Hemerythrin"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01814.25"
                     /description="Hemerythrin HHE cation binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_72_0004"
                     /evalue="3.10E-24"
                     /label="ctg1_72"
                     /locus_tag="ctg1_72"
                     /protein_end="231"
                     /protein_start="85"
                     /score="86.2"
                     /tool="antismash"
                     /translation="HVINTHHAYLNETLPRLSELTTKILRVHGAKHSELAKVHKLLHSL
                     KMELEQHLIKEEEIVFPLIQEYERTGNNETLSNAVEKIIELEEEHEGAGSILKELREVT
                     KNYELPEDACNSYKAAYKLLEDVEDDTFRHIHLENNIMFPRL"
     CDS             complement(5060..5293)
                     /locus_tag="ctg1_73"
                     /transl_table=11
                     /translation="MSEFTASVDVRKYPPRDKHAVIFDTLGKLKSGEAMELINDHDPKP
                     LYYELSAEHEEKFEWEYLQNGPELWRVSIKRK"
     PFAM_domain     complement(5066..5272)
                     /aSDomain="DUF2249"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10006.11"
                     /description="Uncharacterized conserved protein (DUF2249)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_73_0005"
                     /evalue="2.10E-28"
                     /label="ctg1_73"
                     /locus_tag="ctg1_73"
                     /protein_end="76"
                     /protein_start="7"
                     /score="98.1"
                     /tool="antismash"
                     /translation="VDVRKYPPRDKHAVIFDTLGKLKSGEAMELINDHDPKPLYYELSA
                     EHEEKFEWEYLQNGPELWRVSIKR"
     CDS             5561..6373
                     /gene_functions="other (smcogs) SMCOG1286:Pentapeptide
                     repeat protein (Score: 74.1; E-value: 1.4e-22)"
                     /gene_kind="other"
                     /locus_tag="ctg1_74"
                     /transl_table=11
                     /translation="MIDKYNEELKADCKKCFGLCCTALYFSASEGFPEDKEAGRPCLNL
                     QSDFSCIVHKSLRDKGLKGCTAYDCLGAGQKVAQVTFEGQSWSDNTKYADKMFEAFIIM
                     RQLHEMLWYLTEVFKLNKDQDKKSIELLIEETEKRTLLKADELLKLDIEAHRNKVNLVL
                     KNTSELIRTKSGNNSRKKKRVDYFGANLKKANLRGADLRGALLIAANMRGADLSYADLI
                     GADMRDADISGANLEKSIFVTQAQINTTKGDSNTRLPKRITRPSYWAK"
     PFAM_domain     6122..6223
                     /aSDomain="Pentapeptide"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00805.24"
                     /description="Pentapeptide repeats (8 copies)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_74_0006"
                     /evalue="5.10E-10"
                     /label="ctg1_74"
                     /locus_tag="ctg1_74"
                     /protein_end="221"
                     /protein_start="187"
                     /score="38.9"
                     /tool="antismash"
                     /translation="GANLKKANLRGADLRGALLIAANMRGADLSYADL"
     CDS             6504..6677
                     /locus_tag="ctg1_75"
                     /transl_table=11
                     /translation="MNKNRNFMLLAIIAVLQGLVFYGPIATIYRENRGLSVYDIFVIEA
                     INMVLMIILEVP"
     CDS             6786..7721
                     /locus_tag="ctg1_76"
                     /transl_table=11
                     /translation="LLERILLAISISGVSGCDIALLYNSVEEKDSEKAFSLYNSFSVVG
                     YLIATVMSTFIIKISMDLLVLATIFPYGISVIVALFLKDVTCEKRGKESIKRVLMFVIK
                     SPQILIFLISVALESEVCHSITVFLNQLQYKRVNIDIKYYGLILVVIQIVSMISSQAYK
                     LTRKFGKGKTLTFMLFSIAISCIFLVEIKSAFFSILLIVIISFSESIILPVATEIESKS
                     VSLGNRATVLSAYAVIIDIISAVVNLVIGKAANHSLRIAFFMCGILVILAVGLNIIYFT
                     MIKILDVKLEAVLITYLTSFCIHWNMYDIH"
     PFAM_domain     6795..7517
                     /aSDomain="MFS_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07690.18"
                     /description="Major Facilitator Superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_76_0007"
                     /evalue="2.50E-13"
                     /label="ctg1_76"
                     /locus_tag="ctg1_76"
                     /protein_end="244"
                     /protein_start="3"
                     /score="49.8"
                     /tool="antismash"
                     /translation="RILLAISISGVSGCDIALLYNSVEEKDSEKAFSLYNSFSVVGYLI
                     ATVMSTFIIKISMDLLVLATIFPYGISVIVALFLKDVTCEKRGKESIKRVLMFVIKSPQ
                     ILIFLISVALESEVCHSITVFLNQLQYKRVNIDIKYYGLILVVIQIVSMISSQAYKLTR
                     KFGKGKTLTFMLFSIAISCIFLVEIKSAFFSILLIVIISFSESIILPVATEIESKSVSL
                     GNRATVLSAYAVIIDIISA"
     CDS             complement(7669..8016)
                     /locus_tag="ctg1_77"
                     /transl_table=11
                     /translation="MGVATMVTDKYQKCIDACNRCSQACYECFKACLNEPDVNARRTCI
                     SILFECAQMCQMSSALMSMDAQFAIDHCKLCSVICDKCAQECSMFQDPHCQKCANECRT
                     CSNECRMMSGM"
     PFAM_domain     complement(7747..7806)
                     /aSDomain="DUF326"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03860.18"
                     /description="Domain of Unknown Function (DUF326)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_77_0010"
                     /evalue="1.50E-06"
                     /label="ctg1_77"
                     /locus_tag="ctg1_77"
                     /protein_end="90"
                     /protein_start="70"
                     /score="28.1"
                     /tool="antismash"
                     /translation="DHCKLCSVICDKCAQECSMF"
     PFAM_domain     complement(7846..7902)
                     /aSDomain="DUF326"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03860.18"
                     /description="Domain of Unknown Function (DUF326)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_77_0009"
                     /evalue="1.50E-05"
                     /label="ctg1_77"
                     /locus_tag="ctg1_77"
                     /protein_end="57"
                     /protein_start="38"
                     /score="24.9"
                     /tool="antismash"
                     /translation="NARRTCISILFECAQMCQM"
     PFAM_domain     complement(7933..7992)
                     /aSDomain="DUF326"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03860.18"
                     /description="Domain of Unknown Function (DUF326)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_77_0008"
                     /evalue="1.70E-05"
                     /label="ctg1_77"
                     /locus_tag="ctg1_77"
                     /protein_end="28"
                     /protein_start="8"
                     /score="24.7"
                     /tool="antismash"
                     /translation="DKYQKCIDACNRCSQACYEC"
     CDS             8150..9061
                     /gene_functions="transport (smcogs) SMCOG1166:transporter,
                     EamA family (Score: 106.4; E-value: 3e-32)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_78"
                     /transl_table=11
                     /translation="MKSKTIKSNIILLITALIWGLAFTAQSVGMKYVGPFTFNGIRFIL
                     GAICIVPVMLFFKEDKIEENSKYARAALVGGIICGMVNFLGTTLQQIGLMYTTVGKAGF
                     ITGLYIVIVPIIGIFLKHHMGINSWIGVLFALVGLYLLCNTGSFSVGYGETLELSGAFF
                     FAVQIFIIDHFSKKANCYRLAFFQYVTCGAVSLIIALFTEKITFNALYGAAIPILYGGL
                     GSVGIAYTLQIIGQKNAKPSHAAIIMSMESVFGALGGAIILGERMGAKNLIGCGLMLLG
                     MLVAQIKLTKTSKKQIIEKKAV"
     PFAM_domain     8174..8575
                     /aSDomain="EamA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00892.22"
                     /description="EamA-like transporter family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_78_0011"
                     /evalue="2.50E-18"
                     /label="ctg1_78"
                     /locus_tag="ctg1_78"
                     /protein_end="142"
                     /protein_start="8"
                     /score="66.7"
                     /tool="antismash"
                     /translation="NIILLITALIWGLAFTAQSVGMKYVGPFTFNGIRFILGAICIVPV
                     MLFFKEDKIEENSKYARAALVGGIICGMVNFLGTTLQQIGLMYTTVGKAGFITGLYIVI
                     VPIIGIFLKHHMGINSWIGVLFALVGLYLL"
     PFAM_domain     8606..9001
                     /aSDomain="EamA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00892.22"
                     /description="EamA-like transporter family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_78_0012"
                     /evalue="1.40E-19"
                     /label="ctg1_78"
                     /locus_tag="ctg1_78"
                     /protein_end="284"
                     /protein_start="152"
                     /score="70.8"
                     /tool="antismash"
                     /translation="GETLELSGAFFFAVQIFIIDHFSKKANCYRLAFFQYVTCGAVSLI
                     IALFTEKITFNALYGAAIPILYGGLGSVGIAYTLQIIGQKNAKPSHAAIIMSMESVFGA
                     LGGAIILGERMGAKNLIGCGLMLLGMLV"
     CDS             complement(9039..9770)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_79"
                     /sec_met_domain="Abi (E-value: 4.6e-16, bitscore: 56.8,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKSDLFFIFISLAFTVIFLNCTSNSLKGIGLELLFLSIGLITIF
                     ILNKKKLLIPINLKNINCSIVLYTVVLSLLASLLTAYVVCTFSYFNLNYLFQKSASYKI
                     TLLSIFTTIIISPICEEMLFRAAILGILIRKIPVHLSIFIQCIIFAFLHGLSFKTVTFY
                     TALIGGFILGYVFYYTKSILSSILCHSIYNFMSIFAGILSFKISNTSTLILCLLLCSIS
                     IYLTVYCITKIKTLSKQPFSQ"
     PFAM_domain     complement(9186..9455)
                     /aSDomain="Rce1-like"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02517.18"
                     /description="Type II CAAX prenyl endopeptidase Rce1-like"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_79_0013"
                     /evalue="3.10E-15"
                     /label="ctg1_79"
                     /locus_tag="ctg1_79"
                     /protein_end="195"
                     /protein_start="105"
                     /score="56.4"
                     /tool="antismash"
                     /translation="LLSIFTTIIISPICEEMLFRAAILGILIRKIPVHLSIFIQCIIFA
                     FLHGLSFKTVTFYTALIGGFILGYVFYYTKSILSSILCHSIYNFM"
     CDS             10001..10630
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_80"
                     /sec_met_domain="AgrB (E-value: 1.9e-36, bitscore: 122.9,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKGKSSVMEKLAEVVSLKLNKHLKMEGIELIKLKLGVEIIFINIS
                     KLAILFLVSYYFGLIKETIIMLAAFGFLRSNAFGLHAKNSIVCTVMSLLMFVLGAYLSK
                     YLLFNNYMVLASFIIVNLLLFRYAPGDTEAHPLVGAKLRDKLKKQAVLMGMLLMAITLI
                     IPDELIKTCISLSSYFEIISILPITYKVLGRRYKNYYEFERTIKQS"
     PFAM_domain     10055..10549
                     /aSDomain="AgrB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04647.17"
                     /description="Accessory gene regulator B"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_80_0014"
                     /evalue="1.20E-35"
                     /label="ctg1_80"
                     /locus_tag="ctg1_80"
                     /protein_end="183"
                     /protein_start="18"
                     /score="122.6"
                     /tool="antismash"
                     /translation="LNKHLKMEGIELIKLKLGVEIIFINISKLAILFLVSYYFGLIKET
                     IIMLAAFGFLRSNAFGLHAKNSIVCTVMSLLMFVLGAYLSKYLLFNNYMVLASFIIVNL
                     LLFRYAPGDTEAHPLVGAKLRDKLKKQAVLMGMLLMAITLIIPDELIKTCISLSSYFEI
                     IS"
     CDS             10599..10763
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_81"
                     /sec_met_domain="TIGR04223 (E-value: 1.7e-10, bitscore:
                     38.5, seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLKEQLNKVNDKFIKGLGKASMKIGEQANGKCVLVTLYEPKMPE
                     ELLKENIDK"
     aSDomain        10635..10745
                     /aSDomain="TIGR04223"
                     /aSTool="tigrfam"
                     /description="quorum_AgrD: cyclic lactone autoinducer
                     peptide"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_81_0003"
                     /evalue="2.00E-10"
                     /identifier="TIGR04223"
                     /label="ctg1_81"
                     /locus_tag="ctg1_81"
                     /protein_end="49"
                     /protein_start="12"
                     /score="38.5"
                     /tool="antismash"
                     /translation="KFIKGLGKASMKIGEQANGKCVLVTLYEPKMPEELLK"
     CDS             10890..12233
                     /locus_tag="ctg1_82"
                     /transl_table=11
                     /translation="MMQYVELVGIIMNLYVSIFSLYSCRIKWKRLVGMIVITEIISLIF
                     LMLGWQQVTVMAYLIIPCIFMYLQTSDVVLSISLPVAGCLIIIVWDYFLSVLYNYVFLV
                     NQSVIKNDVSIHWITFCIEFIGTYVTSRTIKKFVRDKFKAYNGHLKGTIGVVAAGTLIL
                     MLFVFYNTNVVFAPNNSVVNSNTMRIKGIVLFFSYAILLIIVIRTILRGIIKEMELKSK
                     ENEFQSLQEYTNKLEKLHKDMRGFRHDYINILLSMAGYIQNRDLEGLERFFDDKIMPLS
                     KAMKSNNFKIGLLQNIEVPEIKGMFSAKIIRAQETGIDVYIDVAESIKSFNMEIIDLSR
                     VIGILLDNAIEASEKCDRPSMKVAVINKDKSVMIVIINNYNEEIPPIYKIYKRGFSTKG
                     DNRGIGLSNLKDIIGKYPNVMLDTVIEDNQFKQIIDIKNKIEEGVFNA"
     PFAM_domain     11886..12197
                     /aSDomain="HATPase_c_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14501.8"
                     /description="GHKL domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_82_0015"
                     /evalue="1.10E-19"
                     /label="ctg1_82"
                     /locus_tag="ctg1_82"
                     /protein_end="436"
                     /protein_start="332"
                     /score="70.3"
                     /tool="antismash"
                     /translation="MEIIDLSRVIGILLDNAIEASEKCDRPSMKVAVINKDKSVMIVII
                     NNYNEEIPPIYKIYKRGFSTKGDNRGIGLSNLKDIIGKYPNVMLDTVIEDNQFKQIIDI
                     "
     CDS             12226..12951
                     /locus_tag="ctg1_83"
                     /transl_table=11
                     /translation="MLEVFVCEDNKEQKENFRKIIDNFIIMENLDMKISVVTENPDDII
                     NYVIKNSVSGLYFLDIDLNASINGIQLAAEIRKYDPRGFIVFVTTHAEMSYLTFLYKVE
                     AMDYIIKDNYKNIGDRIYQCIVDAQRKYSAKTTDLQKIFTIKADDRIINIEFQKILFFE
                     TSFTIHKVVLHSVNRQIEFYAKMKDIEGELDDSFYRCHKSYIVNKKNIKEININKRRIY
                     MINGEECLISTRMLKGLIK"
     PFAM_domain     12235..12561
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_83_0016"
                     /evalue="2.40E-15"
                     /label="ctg1_83"
                     /locus_tag="ctg1_83"
                     /protein_end="112"
                     /protein_start="3"
                     /score="56.7"
                     /tool="antismash"
                     /translation="VFVCEDNKEQKENFRKIIDNFIIMENLDMKISVVTENPDDIINYV
                     IKNSVSGLYFLDIDLNASINGIQLAAEIRKYDPRGFIVFVTTHAEMSYLTFLYKVEAMD
                     YIIKD"
     PFAM_domain     12670..12942
                     /aSDomain="LytTR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04397.17"
                     /description="LytTr DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_83_0017"
                     /evalue="1.60E-22"
                     /label="ctg1_83"
                     /locus_tag="ctg1_83"
                     /protein_end="239"
                     /protein_start="148"
                     /score="79.7"
                     /tool="antismash"
                     /translation="DRIINIEFQKILFFETSFTIHKVVLHSVNRQIEFYAKMKDIEGEL
                     DDSFYRCHKSYIVNKKNIKEININKRRIYMINGEECLISTRMLKGL"
     CDS             13031..15100
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070:lanthionine synthetase C family protein (Score:
                     261.1; E-value: 3.4e-79)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_84"
                     /sec_met_domain="LANC_like (E-value: 2.8e-25, bitscore:
                     86.6, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVIMLGRRKNGIAMELKSIETVGDFISLSGNSRRLTSILKVKRLI
                     RENYSIIRSNLLNTEDKVAIKEIKYYEKEERAIVTFTDNEKVVFQSYISKDEEIINKFI
                     RWINQKVDKEHSLYVKKILYAEGCSFSEYIKPINSIGKREIFDYYFKSGELLLILYVLR
                     CSKIKSKNIIDMEDCPILDEVKDAFYSTNDVPSFNFSANEVAEKLVKYSVYNIEFLPES
                     KKSITEEEIYHIKCGFEYIYNMIMYNKLELIEVMKVIFKEDILKLSAVITNIYGLNEED
                     LKRQLYFIDIRFIGVKIARRKVNFCISERKETIDKNYFISIANDLGEHMIKRGIIGVKD
                     FVTSRTWISTTRDGNNQGYSLSPLSSDLMDGSSGVALFFAYLGLVTGKDYYKAIAIEAI
                     QDSINHINNLNNNDDINIGAFKGISGEIYAMWKIYSVTRSNYLEASIENGIRALYILVQ
                     KSKDIDITNGLCGVSCVLVSIYKDKDSNKFNDIIMNLIRICMEKITGNMSSKQMALNDV
                     YLNDAIILTLAKLLELTGERSLVKKIKELFSIQRMKYKDIFARWDRRILITLMGRVTLK
                     KINFQDESIDREIQQISKYIINNGFGNSFSCCDDMGIIEVLKHTAAILSDEKLNSSCIK
                     TFNELVKKKIKPTINKEITYANENISLMNGVVGLAYSLIRISSEKFVPKILWLE"
     PFAM_domain     13259..13720
                     /aSDomain="DUF4135"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13575.8"
                     /description="Domain of unknown function (DUF4135)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_84_0018"
                     /evalue="1.60E-16"
                     /label="ctg1_84"
                     /locus_tag="ctg1_84"
                     /protein_end="230"
                     /protein_start="76"
                     /score="60.7"
                     /tool="antismash"
                     /translation="AIVTFTDNEKVVFQSYISKDEEIINKFIRWINQKVDKEHSLYVKK
                     ILYAEGCSFSEYIKPINSIGKREIFDYYFKSGELLLILYVLRCSKIKSKNIIDMEDCPI
                     LDEVKDAFYSTNDVPSFNFSANEVAEKLVKYSVYNIEFLPESKKSITEEE"
     PFAM_domain     14117..14548
                     /aSDomain="LANC_like"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05147.15"
                     /description="Lanthionine synthetase C-like protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_84_0019"
                     /evalue="6.80E-12"
                     /label="ctg1_84"
                     /locus_tag="ctg1_84"
                     /protein_end="506"
                     /protein_start="362"
                     /score="44.7"
                     /tool="antismash"
                     /translation="PLSSDLMDGSSGVALFFAYLGLVTGKDYYKAIAIEAIQDSINHIN
                     NLNNNDDINIGAFKGISGEIYAMWKIYSVTRSNYLEASIENGIRALYILVQKSKDIDIT
                     NGLCGVSCVLVSIYKDKDSNKFNDIIMNLIRICMEKITGN"
     PFAM_domain     14750..15085
                     /aSDomain="LANC_like"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05147.15"
                     /description="Lanthionine synthetase C-like protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_84_0020"
                     /evalue="1.20E-09"
                     /label="ctg1_84"
                     /locus_tag="ctg1_84"
                     /protein_end="685"
                     /protein_start="573"
                     /score="37.4"
                     /tool="antismash"
                     /translation="TLKKINFQDESIDREIQQISKYIINNGFGNSFSCCDDMGIIEVLK
                     HTAAILSDEKLNSSCIKTFNELVKKKIKPTINKEITYANENISLMNGVVGLAYSLIRIS
                     SEKFVPKI"
     CDS             15442..16041
                     /locus_tag="ctg1_85"
                     /transl_table=11
                     /translation="LKNTRIKDMRDDELQAYIKETKKEIEQQLKLYVKLNNDKLSNNGQ
                     IQNLKKKAYNLKEVYEYIKWANDKIAINNNVESSYGTIPKRGEIWTCQLGENIGSEENK
                     IRPAIIIQNDTGNEKGPTTIIVPISNRPKKISTHIELRPGDYKLVHGEVNKITGTILCE
                     QIKVVSKARLGRHVATLNSDFVNKILNSKLKISIKV"
     PFAM_domain     15694..16023
                     /aSDomain="PemK_toxin"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02452.19"
                     /description="PemK-like, MazF-like toxin of type II
                     toxin-antitoxin system"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_85_0021"
                     /evalue="4.90E-30"
                     /label="ctg1_85"
                     /locus_tag="ctg1_85"
                     /protein_end="194"
                     /protein_start="84"
                     /score="104.2"
                     /tool="antismash"
                     /translation="KRGEIWTCQLGENIGSEENKIRPAIIIQNDTGNEKGPTTIIVPIS
                     NRPKKISTHIELRPGDYKLVHGEVNKITGTILCEQIKVVSKARLGRHVATLNSDFVNKI
                     LNSKLK"
     CDS             16321..16797
                     /locus_tag="ctg1_86"
                     /transl_table=11
                     /translation="MDQLRYTICFIKREDEVLLLNREKPSWMGSWNGVGGKFQNSETPM
                     ECILREIHEETGMKFQEAKFKGIVTWDEGDKDIGGMYLFLIEVPANYNYSVPVKTREGI
                     LDWKKISWVMNPENTGIAANVPKYLPKMLKEEGEFRYHCVFKNKMLLGVNIEEI"
     PFAM_domain     16342..16656
                     /aSDomain="NUDIX"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00293.30"
                     /description="NUDIX domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_86_0022"
                     /evalue="1.60E-10"
                     /label="ctg1_86"
                     /locus_tag="ctg1_86"
                     /protein_end="112"
                     /protein_start="7"
                     /score="41.2"
                     /tool="antismash"
                     /translation="ICFIKREDEVLLLNREKPSWMGSWNGVGGKFQNSETPMECILREI
                     HEETGMKFQEAKFKGIVTWDEGDKDIGGMYLFLIEVPANYNYSVPVKTREGILDWKKIS
                     W"
     CDS             16861..17040
                     /locus_tag="ctg1_87"
                     /transl_table=11
                     /translation="MEPGDIVRIDDDNEWKGLYGVVKYTNQSEAFIFCVQNPCYLYKAT
                     TENNVAIVIKRSER"
     CDS             complement(17046..18125)
                     /locus_tag="ctg1_88"
                     /transl_table=11
                     /translation="MSNYEKVYIGTYTNGESRGIYSFNIISDSRKTTAPILSCEIENPT
                     YLTFNMNNKTAYSVIKSGNLGGAASFYVDDRNNHLELLNCKFGYENPPERFSGKQPCYV
                     SLDKTNSYLFSVNYHTSRVDVFPIRNDGSIDTVSSFVIHEGFGPNKERQETSHVHCAVT
                     TPLNDFLCVVDLGTDKIVLYRFDDGILCRFNEFKLKPGCGPRHIIFHPNGKIAYIATEL
                     SSEVIVLKYSPLDGSFEELQYVSCLPTDYTGKNGSAAIHISRNSNYLYVSNRGHNSISC
                     FHVDNSTGLLTLNSNTSTYGLSPRDFDLSSSGNLLIAANQDSSNLTIFSVDQVSGNLSK
                     ITSDIYVPNPVCVKFYHDK"
     PFAM_domain     complement(17061..18107)
                     /aSDomain="Lactonase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10282.11"
                     /description="Lactonase, 7-bladed beta-propeller"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_88_0023"
                     /evalue="6.00E-125"
                     /label="ctg1_88"
                     /locus_tag="ctg1_88"
                     /protein_end="355"
                     /protein_start="6"
                     /score="417.1"
                     /tool="antismash"
                     /translation="VYIGTYTNGESRGIYSFNIISDSRKTTAPILSCEIENPTYLTFNM
                     NNKTAYSVIKSGNLGGAASFYVDDRNNHLELLNCKFGYENPPERFSGKQPCYVSLDKTN
                     SYLFSVNYHTSRVDVFPIRNDGSIDTVSSFVIHEGFGPNKERQETSHVHCAVTTPLNDF
                     LCVVDLGTDKIVLYRFDDGILCRFNEFKLKPGCGPRHIIFHPNGKIAYIATELSSEVIV
                     LKYSPLDGSFEELQYVSCLPTDYTGKNGSAAIHISRNSNYLYVSNRGHNSISCFHVDNS
                     TGLLTLNSNTSTYGLSPRDFDLSSSGNLLIAANQDSSNLTIFSVDQVSGNLSKITSDIY
                     VPNPVCVKF"
     CDS             18227..19105
                     /locus_tag="ctg1_89"
                     /transl_table=11
                     /translation="MEDNYKNLKIAERGVRISLIIYVVLSIFKFFMGYFFKSEALKADG
                     INSSTDIIAAIAIIVGLKIARKPADKEHTYGHLRAETISSLLASLIMIAVGVDVVYNGV
                     KNTIFLRNEKPDIKAAIVSLICASVVYTLYRYNRSVADKIHSSALMVSSKDNLSDSMVG
                     FGSAFGIFASQFGFPWMDSITAVLVGIIICKTGFGIFREAVNNLTDAFDPEKLENITKI
                     IKDIDGVSDIKDIRARVHGNSILLDAIILVDPGLSVRESHEITEAVEKILKEEFNIRNA
                     IIHVEPNIDEL"
     aSDomain        18260..19090
                     /aSDomain="TIGR01297"
                     /aSTool="tigrfam"
                     /description="CDF: cation diffusion facilitator family
                     transporter"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_89_0004"
                     /evalue="1.30E-62"
                     /identifier="TIGR01297"
                     /label="ctg1_89"
                     /locus_tag="ctg1_89"
                     /protein_end="288"
                     /protein_start="11"
                     /score="209.6"
                     /tool="antismash"
                     /translation="ERGVRISLIIYVVLSIFKFFMGYFFKSEALKADGINSSTDIIAAI
                     AIIVGLKIARKPADKEHTYGHLRAETISSLLASLIMIAVGVDVVYNGVKNTIFLRNEKP
                     DIKAAIVSLICASVVYTLYRYNRSVADKIHSSALMVSSKDNLSDSMVGFGSAFGIFASQ
                     FGFPWMDSITAVLVGIIICKTGFGIFREAVNNLTDAFDPEKLENITKIIKDIDGVSDIK
                     DIRARVHGNSILLDAIILVDPGLSVRESHEITEAVEKILKEEFNIRNAIIHVEPN"
     PFAM_domain     18272..18847
                     /aSDomain="Cation_efflux"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01545.23"
                     /description="Cation efflux family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_89_0024"
                     /evalue="1.20E-41"
                     /label="ctg1_89"
                     /locus_tag="ctg1_89"
                     /protein_end="207"
                     /protein_start="15"
                     /score="142.8"
                     /tool="antismash"
                     /translation="RISLIIYVVLSIFKFFMGYFFKSEALKADGINSSTDIIAAIAIIV
                     GLKIARKPADKEHTYGHLRAETISSLLASLIMIAVGVDVVYNGVKNTIFLRNEKPDIKA
                     AIVSLICASVVYTLYRYNRSVADKIHSSALMVSSKDNLSDSMVGFGSAFGIFASQFGFP
                     WMDSITAVLVGIIICKTGFGIFREAVNNL"
     PFAM_domain     18860..19087
                     /aSDomain="ZT_dimer"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF16916.7"
                     /description="Dimerisation domain of Zinc Transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_89_0025"
                     /evalue="1.30E-20"
                     /label="ctg1_89"
                     /locus_tag="ctg1_89"
                     /protein_end="287"
                     /protein_start="211"
                     /score="73.4"
                     /tool="antismash"
                     /translation="DPEKLENITKIIKDIDGVSDIKDIRARVHGNSILLDAIILVDPGL
                     SVRESHEITEAVEKILKEEFNIRNAIIHVEP"
     CDS             19191..19679
                     /locus_tag="ctg1_90"
                     /transl_table=11
                     /translation="MKKIIFAGGCFWGVEAYFNTIDGVLNTKVGYANGNTEDPTYEDVC
                     TDSTGYAEACYIEYDEKQLKLEKLIDAYWKVVDPTLKNRQGHDEGTQYRTGIYYVDEED
                     LKVILESKDKEQEKYDAPIVTEILPLKNFYDAEEYHQKYLDKNPNGYCHIPKELLKKH"
     aSDomain        19194..19646
                     /aSDomain="TIGR00401"
                     /aSTool="tigrfam"
                     /description="msrA: peptide-methionine (S)-S-oxide
                     reductase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_90_0005"
                     /evalue="5.40E-66"
                     /identifier="TIGR00401"
                     /label="ctg1_90"
                     /locus_tag="ctg1_90"
                     /protein_end="152"
                     /protein_start="1"
                     /score="219.7"
                     /tool="antismash"
                     /translation="KKIIFAGGCFWGVEAYFNTIDGVLNTKVGYANGNTEDPTYEDVCT
                     DSTGYAEACYIEYDEKQLKLEKLIDAYWKVVDPTLKNRQGHDEGTQYRTGIYYVDEEDL
                     KVILESKDKEQEKYDAPIVTEILPLKNFYDAEEYHQKYLDKNPNGYC"
     PFAM_domain     19197..19649
                     /aSDomain="PMSR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01625.23"
                     /description="Peptide methionine sulfoxide reductase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_90_0026"
                     /evalue="1.10E-64"
                     /label="ctg1_90"
                     /locus_tag="ctg1_90"
                     /protein_end="153"
                     /protein_start="2"
                     /score="217.3"
                     /tool="antismash"
                     /translation="KIIFAGGCFWGVEAYFNTIDGVLNTKVGYANGNTEDPTYEDVCTD
                     STGYAEACYIEYDEKQLKLEKLIDAYWKVVDPTLKNRQGHDEGTQYRTGIYYVDEEDLK
                     VILESKDKEQEKYDAPIVTEILPLKNFYDAEEYHQKYLDKNPNGYCH"
     CDS             19713..20669
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1072:dehydrogenase (Score: 320.1; E-value: 1.7e-97)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_91"
                     /transl_table=11
                     /translation="MRISVIEPLGISEEEIRSIAKTITDRGHEIVIYNEKSTDTNVLKE
                     RVKDSEVIVLANMPLKAEVINSDSKLKMMSIAFTGVDHVELSALNNKEVVVSNASGYST
                     ESVTELTFGLVFSVLRNIVPLDKVTREGKTKNGFSQSDLSGKTFGVIGTGLIGASVCRI
                     AKAFGCKVIAYSRSKKEELEVIGVNYVTLDELLAKSDVISVHVPQTQETIGMISKEKIK
                     LMKKTAILINVARGPIVDNEALAEALENGTIAGAGIDVFDKEPPLDLGYRLLKAPNTVV
                     LPHVGFATKEAMVRRAHITFENIVKWLDGTPQNIVKY"
     PFAM_domain     20046..20570
                     /aSDomain="2-Hacid_dh_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02826.21"
                     /description="D-isomer specific 2-hydroxyacid
                     dehydrogenase, NAD binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_91_0027"
                     /evalue="1.40E-59"
                     /label="ctg1_91"
                     /locus_tag="ctg1_91"
                     /protein_end="286"
                     /protein_start="111"
                     /score="200.5"
                     /tool="antismash"
                     /translation="FGLVFSVLRNIVPLDKVTREGKTKNGFSQSDLSGKTFGVIGTGLI
                     GASVCRIAKAFGCKVIAYSRSKKEELEVIGVNYVTLDELLAKSDVISVHVPQTQETIGM
                     ISKEKIKLMKKTAILINVARGPIVDNEALAEALENGTIAGAGIDVFDKEPPLDLGYRLL
                     KAPNTVVLPHVG"
ORIGIN
        1 aataatatat gtaaaatgaa gaagaacgaa ttgtccttgt tcagaagaaa taatatcggt
       61 atggtgtttc aagatttcaa tctcctaaac agcttaactg taaaagaaaa tattatggtt
      121 cccttaattt tagataagaa atatgaaatt atggatggaa atacggtgat ggagcttgca
      181 aaaaggtttg atatgggaga gataatggac aaatatcctt atgaaatatc aggtggacaa
      241 aagcaaagag cagctatttg tagagctatt gtaaataacc ccaaaataat atttgctgat
      301 gagccaacag gtaatcttga ttcaagatca tctaaaaagg ttctatcgta ctttgaagtt
      361 atgaatagtg aatacaacgc aagtatacta atggtaacac atgatgccta ttctgcaagt
      421 tactgtgata gagtagtgtt tcttaaggat ggttcaataa ttaaggaaat tagaaagcag
      481 ggggataaga ctaagttttt tagctgtatt atgaaaactc ttgaggattt gaatactgtc
      541 aaagaaagtt taagggagga aaaatagaat atgaccttta gtgaaattgc atataaaatg
      601 tttaaaaaag atgctaaaaa atatagacta tttatattat gcaatgtggc agcaattgct
      661 gttttatata gttttatatc aatagtttta aataagcagt tcatgaattc ttccatagtt
      721 gatccgatga tatcaagcaa tatatatgct ccaactttct tcatagtaat gtttgcaggt
      781 atgtttattc catattccca aagtgtattt atgaaggcaa ggcaaaagga ttatggcatt
      841 ttgttatcaa taggtatgac agaaaacgag gttagaaaaa gcgtcataat agaaaattta
      901 gtactgcatg cagtttcatt agtagctggt ctaatgtttg gaacaatttt atcattattt
      961 tttttaggtt ttatacatag tataatagga atttctaata ttaatgttac tgtttctgta
     1021 gtgtcatatg aaatggtaac tgtatgtgaa ttaatattat ttattatttc tttaattgtt
     1081 aactgttata gtatggttaa aagtactata tacgcaaaga taaagcatac tgaaaaaact
     1141 gaaagtacag gacgttatag tattaaattt atttttatag ggctagttat aacaattgca
     1201 ggacttattc tagttgcttt tttttatgaa aataatgaca atattggtct aatgggttta
     1261 ttaatttgaa cagtaggatc aacattgata ttttttaatg gagaagcttt aattggatgc
     1321 tttgaaggca ggaattataa gaagtacatt agaaatattt ttttattttc agatatgaaa
     1381 tattattatg gtaaaaataa aaaggtgttt ttggtaagtt catggttgat ttttgtagta
     1441 atgttttttt cagcacttag ttttattaat tatcctagtt ccattaaata tgcttatact
     1501 tatcatccat ttcatatggc atatggagat ataaaggatg gccttaaacc attagatgat
     1561 aatgaagttg catcaattgt gcataagaat aataatagta taacacgaag caatactgtt
     1621 aaatttttaa ggaatagagt ttttacagtt ttttctgtta atgatgtaaa tagaacatta
     1681 aaaaccaatt atagagtcaa accgaattta tttatatatg ttcatcctta tgatataaat
     1741 gacggatata agagggagga cattaatata agaattccta gtattgatat taactctgat
     1801 gatggagtaa gaaagtttaa ggttcaagat acaattatta aaccattgtt tggtcaaata
     1861 aattgcatat caaataatat aattttagtt aatgaagatg attacaactg gattgcatta
     1921 aatggaacgg attatgtgtt taagggtaca ttgcacttat ataattttgc tagctggaga
     1981 aactctaatc ctatagtaaa tgaagtaagg aaaagattac taaaagggaa taatagaagt
     2041 aaggaagatg ctttttataa aataagttca aaagtagagg catataacac gagcttaaag
     2101 agttgtaatt ttttaatttt taaccttata tacatatgtg ttcttttata tttttctgtt
     2161 tttataatga ttcattataa attgatgatg gaatataaag atgatcaaat gagatatttc
     2221 agcctttata agattggaat agatgaaata gagataaaaa gaatagtaaa acaaaaaata
     2281 cttatgacat attttatacc atttatatat gcggttataa tcaatattcc ctttagctat
     2341 tatgttttca attcacatat acatagtggt ttagaaaatc caatcataat aactacgtca
     2401 attgcttttt ttataataca tcttgttatg tgtaaattat atacaaatgt atattataaa
     2461 agaattattt cagaattacc ttaagaagat aatttaataa aacaaggtat ttacatttta
     2521 ggaatagtac ataattataa atagatttca tccaaaattg taacaaatat tacggttaac
     2581 tttttctcaa aaagtaagat aataatagat aggaagtaat acagatctta aaataaaaca
     2641 caactaaaga taagtcattt tggagggaga attatttatg tttgtatgga aggacgaatt
     2701 tgagttaggg attgataaaa ttgacaatga gcacagaaaa ctttttgaaa tagctaataa
     2761 aggatatgag cttttaaaaa atgagtttta tgtggacaag tacgacaaaa taatggatat
     2821 aatagtagaa ttaaaggagt atgctgaatt ccatttttca gaggaagaag attaccttgc
     2881 aagtataggg tataagaagt tgtttaccca taagcttgaa cacgattcat ttataaaaaa
     2941 ggttgaaagt tttaatatta aagaaattga ctatgatcaa gataaatata tacaagaaat
     3001 gctggatttt gttgttactt ggatcaaaga acatatatta gaaaaggata gagaatatat
     3061 agattaagta tagtaagtgc tgccttaaag ttaataaagg cagcacttat tttatactaa
     3121 aagaatttaa aataagccat ttaatgcttt attgtccgtt tttacaattg attttatact
     3181 gctataaggt atttttagct cagcatgatc cccagcagca tgagttatac cgatactaat
     3241 aacaagacca tcctttgtca gataactaaa ggcacttgaa ggattttctt gaccaattgg
     3301 attatctgat ttttcaaatg ctgtttgtaa atagctatca ttataagtac ttatctcttt
     3361 agatatggtt tgcgaatcaa tagaactgtt ataaggaata taagctcctt ttctaaaagt
     3421 atttataagt gtttgattta ttgaaaacat tccttgcaag ttcattgttt ttgcattatt
     3481 tatatctatg tttgtagtat acaattcatt attaggatga gcactgcctt tcatattaga
     3541 agatcctaaa tatctaatac ttaatatatt tgagttctgt aattctacag tgtaattaac
     3601 gtttaaagtt aagttttcta taggttcatt ataatttggt agagttttag ttttaattgc
     3661 ttgcgttaaa ttaaagccgt ttatcacaga atctttaatt aaattattta ttgctaattg
     3721 tttgttatta tcgcctaaat tagatatctg cggataatta atttttatgt tagcaattgt
     3781 ataggtattt tgagctatgc tgtacatact actaggttta tttgttggag ctggagtact
     3841 tgaagtagct ttattatttg gagtattgct atttgtagtt ttgctagtac ttttagtatt
     3901 attttcactt gatgaattta tgttttctga ttgctttgga tcttttgctg tactagtatt
     3961 tggagcttta gctgtactta cctttgattg ttttgaaggt gtttttgatt gatcattgct
     4021 ttggctattg ctgcaacctg ccataataaa aatactggca ccgattaatg ttgttaataa
     4081 tattttttta ttcataattt ataaaacctc cgattatgga tttaagtact attgcatgat
     4141 aaattataca tccgttgtga tctaaaattc aatggggatt taaaaaaata catataattt
     4201 aaagaaactt caaaatttaa ctttaattat agaattaata gcttgaattc gggtaaatta
     4261 tcaataaaga ataaattaac tggaggtaaa aaatgcaaaa tgtatttaat gtaaatcaaa
     4321 agattgggga tatagtagtt aagtttccaa gagctattga aatacttaaa agatataaaa
     4381 tagatttttg ctgtggagga gatagagtac ttgaagaggc aataaaggaa caagggctta
     4441 atggacaaga aataatagat gaaataaatg aggattataa taaatatata atggaggaag
     4501 taaaggatag agattgggca actgaaccat attcaaaatt aatagaacac gttataaaca
     4561 cacatcacgc atatttaaat gaaacgctgc cgcgcttaag cgagcttaca actaaaatac
     4621 ttagagtgca tggagcaaaa cattctgaat tggctaaggt gcataagctt ctgcatagct
     4681 taaaaatgga attagaacag catttgataa aagaggagga aatagtattt ccgctcatac
     4741 aggaatacga aagaacggga aataatgaga ctttaagtaa tgctgtagaa aagattatag
     4801 aattagaaga ggaacatgaa ggtgcaggct caatactaaa ggagcttagg gaggttacta
     4861 agaattatga gcttcctgaa gatgcctgca acagctataa agcagcatat aaacttttag
     4921 aggatgtaga ggatgatacc tttagacaca tacatcttga aaataatatt atgtttccaa
     4981 ggcttgttag tgaatcaaag aagcataagt aataagaagg cgcaaaagta tttatcatac
     5041 tctagcgtct ttttatgatt tatttccttt taatagatac cctccagagt tctgggccgt
     5101 tttggaggta ttcccattca aatttttcct cgtgttctgc tgaaagttca tagtatagtg
     5161 gttttggatc atggtcattt ataagttcca ttgcctctcc agatttaagc ttacccaatg
     5221 tatcaaatat tactgcatgc ttatctctag ggggatattt tcgcacatct acacttgctg
     5281 tgaattcaga catttagaga tcatcctttc atatctaatt tattatttaa gatattgttt
     5341 gcttaattgc attattttat atatgaatat tattttttgt aaataggtgt gagggaaaat
     5401 tgataatgtt gtgttggggt atgtcatatg cttaagaaag agattaagga tgattttgta
     5461 ataaatgaag agtacaagga tgaaggaagc attaaaataa tagtgtactt cttttgtgat
     5521 ataatttaaa aataacacta aatatatgag gtaaacaaat atgattgata aatataatga
     5581 agaactaaag gcagattgta aaaaatgttt tggactatgc tgcacagctt tatatttttc
     5641 tgcgtcagaa ggctttccag aagataaaga agcaggtagg ccttgtttga atttgcaatc
     5701 ggacttttca tgcatagtac acaaaagtct tagggataag gggcttaaag ggtgtacagc
     5761 ttacgattgc cttggagcag gacaaaaggt agcacaggtt acatttgaag ggcaaagttg
     5821 gagcgataac actaaatatg ctgataaaat gtttgaagct tttattatta tgagacaact
     5881 tcatgaaatg ttgtggtatc ttacagaagt atttaaacta aataaggacc aggataaaaa
     5941 gagtatagaa ttacttatag aagaaacaga aaaacgtact cttttgaagg ctgatgaatt
     6001 attaaaactt gatatagaag ctcatagaaa taaggttaac cttgtgctta aaaataccag
     6061 cgagcttata cgtaccaaaa gtggaaataa ctcaagaaag aaaaagaggg tagattattt
     6121 tggcgctaat cttaaaaagg ctaatcttag gggagcagat cttagagggg ccctacttat
     6181 tgcagcaaat atgagaggtg cggatttaag ttacgctgat ttaattggtg cagatatgag
     6241 agatgcagat attagcggag caaatttaga aaaaagtata tttgttactc aagcccagat
     6301 aaataccact aagggagatt ctaatacaag gcttcctaaa agaataactc gtccaagtta
     6361 ctgggcaaag taattaaatg taaaatgtaa aggagcatga aaatgatttt aatttatatg
     6421 ccttgataaa aaaatatgta taaaaagttt tatagccttt tgttaggctt ttttgttgtg
     6481 catattttgg aggtatataa ataatgaata agaatagaaa ttttatgctt ttagctatta
     6541 ttgcggtgct acaggggctt gttttttatg gaccaattgc aactatctat cgtgaaaata
     6601 ggggattaag tgtatatgat atatttgtaa tcgaagctat aaacatggta ttaatgatta
     6661 tacttgaagt accatagggg tggtttgctg ataaattcgg ttacaaaaaa actctattta
     6721 tctcgctttt agtaaatttt atttcaaaga tagtttttta tagggcacat tcttttaatt
     6781 tatttttgct tgagagaatt ttacttgcaa tatcaatttc aggagtttca ggatgtgata
     6841 ttgcactatt atacaattcg gttgaagaga aagattctga gaaggcattt agcttatata
     6901 attcgttttc tgtagtaggg tatcttatag ctacagtaat gtctacattt ataattaaaa
     6961 tatctatgga tttattagta ttagctacaa tatttccata tgggatttca gttattgtag
     7021 cattattttt gaaagatgtg acatgtgaaa aaaggggcaa agagagtatt aaaagagtat
     7081 tgatgtttgt aattaaaagc ccccaaattt taatatttct aatttctgtg gctttagaat
     7141 cagaggtttg tcattcaatt acagtgtttt taaatcaact tcaatataag agagtaaata
     7201 tagatattaa gtattatggg ttaatacttg tagttattca gattgtttca atgatttcat
     7261 cacaggcata taagcttact agaaaatttg gaaaaggcaa gacacttacg tttatgttat
     7321 tttctatagc aattagttgt atcttcttag tggaaataaa aagtgctttt tttagcattt
     7381 tacttattgt aattattagt tttagtgaat ccattatact tcctgtagca acagaaattg
     7441 aaagtaagtc agtaagccta ggaaataggg caactgttct ttcagcctat gctgtgatta
     7501 ttgacattat atcagcagtt gttaatttag ttataggtaa agctgctaac cattcactta
     7561 gaatagcatt ttttatgtgc ggcatacttg tcattttagc agttggttta aatattattt
     7621 attttacaat gattaagatt ttagatgtaa aattagaagc agtattgatt acatacctga
     7681 catcattctg cattcattgg aacatgtacg acattcatta gcacattttt ggcaatgggg
     7741 atcttgaaac atagagcact cttgagcaca tttatcacaa attactgaac aaagtttaca
     7801 gtgatctatt gcaaattggg catccataga cataagagct gatgacattt gacacatttg
     7861 agcacattca aacaaaatgc ttatacaagt tcttctagca ttaacatcag gttcatttaa
     7921 acaagctttg aaacattcat aacaggcctg agaacatcga ttacatgcat caatacattt
     7981 ttgatattta tctgttacca tagttgcaac acccatttta aacactcctc tatagttttt
     8041 aattattaca aatattagtc tgcgttatta ggatgttttt attcttaaag agaaattttt
     8101 aaatattata tatgatataa tattatttaa aaattagtga ggtgacagga tgaaatccaa
     8161 aactattaag tcaaatataa ttttactaat tactgcactc atatggggat tagcttttac
     8221 tgctcaaagt gttggtatga agtatgtagg accatttacg tttaatggta taaggtttat
     8281 actaggtgca atttgtatag ttccagtaat gctgtttttt aaggaagata aaatagaaga
     8341 aaacagtaaa tatgcaagag cagctcttgt tggtggaatt atatgtggaa tggttaattt
     8401 tttaggaaca acgcttcaac aaattggact tatgtataca acggtaggaa aggctggttt
     8461 tataactggg ttatacattg taattgtacc tataataggc atatttttaa aacatcatat
     8521 gggcataaat tcatggatag gagttttatt tgccctagtt ggactctatc ttttatgtaa
     8581 tacgggaagc ttttctgttg gatatggtga aacgcttgaa ctttcaggag cttttttctt
     8641 tgcggttcaa atatttataa tagatcattt cagtaaaaag gcaaattgtt ataggttagc
     8701 attttttcag tatgtaacct gtggtgcagt tagtttaatt atagcattat ttacagagaa
     8761 gataactttt aatgcattat atggagcagc aattcctatt ctttatggag gactaggatc
     8821 agttggaatt gcatatactc ttcaaattat cggtcaaaaa aatgccaagc cttctcatgc
     8881 cgctataata atgagcatgg aatctgtttt tggagcgctt ggtggagcta taattttagg
     8941 tgaaagaatg ggtgcgaaaa acctaattgg atgcggatta atgctcttag gtatgttagt
     9001 tgctcaaatt aagcttacaa aaacatcaaa aaaacaaatc attgagaaaa aggctgttta
     9061 gataaagttt ttatcttcgt aatacaatat acagtgagat atatactaat tgaacataga
     9121 agcaagcaga gtattaaggt agaagtatta gaaattttaa aggataaaat acctgcaaag
     9181 atactcatga aattataaat tgagtggcat aggatagatg aaagtattga ttttgtatag
     9241 taaaaaacat atcctagaat aaatccacct ataagagcag tataaaaggt aacagtttta
     9301 aaacttaaac catgcaaaaa tgcaaaaata atacattgaa taaaaattga taaatgtact
     9361 ggtatttttc gtataagtat acctaaaata gcagctctaa ataacatttc ttcacatata
     9421 ggacttataa taatagtagt aaatatgctc aaaagcgtga ttttgtaaga ggcgcttttt
     9481 tgaaataaat agtttaaatt aaaataggag aaagtacaga ctacataggc tgtcaaaaga
     9541 gatgcaagta aacttaatac aacagtatat aggactattg aacaattaat gttttttaaa
     9601 ttgattggta tcaatagttt tttcttgttt aaaataaaaa ttgttattag accaatagat
     9661 aaaaaaagca gttcaagtcc aatgcccttt aaagaattgc ttgtacaatt gagaaaaatt
     9721 acagtaaaag ctaaagatat aaatataaaa aacaaatcag attttttcat tacaaactcc
     9781 acctatatat taataattct taccaaaata tatcataata atgagtactt tacaaacaac
     9841 aaatttccag agaaaaatac agtcgcttat tacaataaaa ttaacacttg ttacagaaaa
     9901 aggctaattg taatacattt gttatttatt ataagcaata tagtatatat tttagttagt
     9961 ataaggttaa ggtcgtataa ttaaattaaa ggtaagggat atgaaaggaa aatcaagtgt
    10021 tatggaaaag ttagcagaag ttgtttcttt gaaattgaac aagcatctaa aaatggaggg
    10081 tatagagtta ataaaattaa aattaggagt agagataatt tttataaata tatctaagct
    10141 tgcaatttta tttttagtat cgtactattt tgggcttata aaagaaacta ttataatgct
    10201 tgctgcattt ggattcctaa gatcaaatgc atttggacta catgcaaaga atagcatagt
    10261 ttgtacagtg atgtcccttt taatgtttgt attaggagca tatttaagta aatatttatt
    10321 atttaataat tatatggttc tggcgtcttt tataatcgta aacctacttc tatttagata
    10381 tgcgcctgga gatacagagg ctcatccttt agttggagct aaactgaggg acaagctaaa
    10441 aaaacaggct gtacttatgg gaatgctttt aatggcaata actttaataa taccagatga
    10501 attaataaaa acatgtatta gtttatcaag ttattttgaa attataagta tattgccaat
    10561 aacatataag gtattaggaa ggaggtacaa gaattattat gaatttgaaa gaacaattaa
    10621 acaaagttaa cgataagttt atcaaaggac ttggtaaagc ttcaatgaaa attggagaac
    10681 aggcaaatgg aaagtgtgta ttggtaacat tgtacgaacc taaaatgcct gaagagctac
    10741 ttaaggagaa tattgacaaa taaaacaata aataaataaa aaacaatggt tataattaaa
    10801 tttaaattat aaccattgtt ttttatttat tgaaattata gtataattta agagatatag
    10861 tattacaaaa aaggggaatc gtatcaaata tgatgcagta tgtagaatta gttggaatta
    10921 taatgaattt atacgtatca atttttagcc tgtattcatg cagaattaaa tggaaaaggc
    10981 ttgtaggtat gatagtgata actgaaatta tttcgttaat atttttaatg cttggttggc
    11041 aacaggttac ggttatggct tatctaataa taccttgtat atttatgtat ttacagacat
    11101 cagatgtggt tttaagtata tctctacctg tagctggatg ccttataatt attgtatggg
    11161 attatttttt aagtgttctg tataattatg tatttttagt gaatcaatcg gttataaaaa
    11221 atgatgtttc aatacactgg attacttttt gcattgagtt tattggaaca tatgttacaa
    11281 gtagaaccat taaaaaattt gtaagggata aatttaaagc ttacaatgga cacttgaaag
    11341 gaacaatagg tgttgttgca gctggaactc ttatattgat gctttttgta ttttataata
    11401 ccaatgtagt ttttgctcct aataattctg tggtaaatag taatacaatg agaataaaag
    11461 gaatagtatt atttttttcg tatgcgatat tgctaataat agtaattcgt acaattttaa
    11521 gaggtattat taaggaaatg gaactaaaaa gtaaagaaaa tgaatttcag agtttacagg
    11581 aatatacaaa taaacttgaa aaacttcata aagatatgag agggtttagg catgattaca
    11641 taaatatatt gttgtcaatg gcagggtata tacaaaatag agatttagaa ggtttagaga
    11701 gatttttcga tgataaaatt atgccactta gtaaggctat gaagtcaaat aactttaaaa
    11761 taggcttgct tcaaaatata gaggtgcctg aaattaaggg gatgttctca gcaaaaataa
    11821 taagagctca ggaaactgga atagatgtat atattgatgt agcagaaagc ataaagagtt
    11881 ttaacatgga aattatagat ttaagcagag taataggaat tttattggat aatgctattg
    11941 aagcttcaga aaaatgtgac aggccatcca tgaaggttgc cgtaataaac aaagataaat
    12001 ctgtcatgat agtgataata aataattata atgaggaaat tccaccaata tacaagattt
    12061 ataaaagagg attttctaca aaaggtgaca acagagggat tgggcttagt aatttaaaag
    12121 atattatagg gaagtaccct aatgttatgt tggatacagt tatagaggac aatcagttta
    12181 agcaaattat tgatataaaa aacaagatcg aagaaggtgt ttttaatgct tgaagtattt
    12241 gtatgcgaag ataataagga acaaaaggag aactttagaa agataataga taattttata
    12301 ataatggaaa acttggatat gaagatatct gtagtaacag aaaatccaga tgatattata
    12361 aactatgtca ttaaaaatag tgttagcggt ttatattttt tagatataga tttgaatgct
    12421 tctataaatg ggatacagct agctgctgaa ataagaaaat atgatccaag gggatttatt
    12481 gtatttgtta caacacatgc agaaatgagt tatttgacgt ttctgtataa agtagaggct
    12541 atggattata taataaaaga taattataaa aatataggag ataggatata ccagtgtata
    12601 gtggatgcac aaagaaaata ttcagcaaaa acaacagatc ttcaaaaaat ctttactata
    12661 aaagctgatg atagaattat aaatatagaa tttcaaaaga ttcttttttt cgaaacttct
    12721 tttacaatac ataaagttgt tctacattct gtaaataggc aaatagaatt ttatgcaaaa
    12781 atgaaggata tagagggtga attggacgac tctttttatc gatgtcataa atcgtatata
    12841 gtaaataaga agaatattaa ggaaattaac ataaataaaa ggcgtattta tatgattaat
    12901 ggagaagaat gtctcatatc aactaggatg ttaaagggac ttattaaata aaacaagcat
    12961 tacattacat aaaatccaac gaatattaca aaaataatta gctatcacat atttatgata
    13021 tattcatatt atggtaatta tgttgggaag gagaaaaaat ggaatagcta tggaattaaa
    13081 aagtatagaa acagttggag attttataag tttaagtggt aatagtagac ggctcacttc
    13141 catactaaaa gtaaaaagac tcataagaga aaattactca attataagaa gtaatttact
    13201 gaacacagaa gataaagtag caatcaaaga aataaaatat tatgaaaagg aggaaagggc
    13261 tatagtaact tttaccgata atgaaaaagt tgtgtttcaa tcttatatat caaaagatga
    13321 ggaaataata aacaagttca taagatggat caaccaaaaa gtagataaag aacatagttt
    13381 atatgttaaa aagatattat atgctgaagg atgtagtttt tctgaataca taaaacccat
    13441 caattctata ggtaaaagag aaatttttga ttattacttt aaatcagggg aacttttatt
    13501 aatactatat gtactaagat gcagtaaaat taaaagtaag aacataatag atatggaaga
    13561 ttgtccgata ttagatgagg ttaaggatgc gttttattca acaaatgacg taccaagctt
    13621 taatttttct gcaaatgaag tagcggaaaa attagtaaag tattctgtat acaatataga
    13681 attcttacca gaaagtaaaa agtctataac agaagaagag atatatcata taaaatgcgg
    13741 gtttgagtat atttataata tgattatgta taataaattg gaattaatag aagttatgaa
    13801 ggttatattt aaagaagata tacttaaatt atcagcggtt attacaaata tatatgggct
    13861 taatgaagaa gatttaaaaa gacaattata ttttatagat ataaggttta taggcgttaa
    13921 aattgcaagg agaaaagtaa acttctgcat tagtgaaagg aaggagacaa tagataaaaa
    13981 ctattttata agtatagcta atgacttggg agaacatatg attaagcgtg gaattattgg
    14041 tgttaaggat tttgtcacga gtaggacatg gataagcact actagagacg gaaacaatca
    14101 aggttattca ttatctccac taagtagcga ccttatggac ggaagtagtg gagtagcttt
    14161 gttttttgcg tatttaggac ttgttactgg caaggattac tataaagcaa tagctataga
    14221 agctattcaa gattctataa atcatattaa taatttaaac aataatgacg atattaatat
    14281 aggtgccttt aaaggtatat caggtgagat atacgctatg tggaagatat atagtgttac
    14341 gcgtagtaat tacttagaag catctattga aaacggtata agagctcttt acatattagt
    14401 tcaaaaaagc aaggatatag atataacaaa tggtttatgt ggggtatcat gtgttttagt
    14461 atcaatatat aaagataagg attctaataa attcaatgat attataatga atttaattag
    14521 aatatgtatg gaaaagataa cagggaatat gagttctaaa caaatggcgt taaatgacgt
    14581 gtacttaaat gatgctataa tacttaccct tgcaaaacta ttagaattaa caggtgaacg
    14641 tagtttagta aaaaagatta aagaattatt cagtattcaa agaatgaaat ataaagatat
    14701 ctttgctaga tgggatagaa gaatacttat aactcttatg gggagagtta ctttgaaaaa
    14761 aataaatttt caagatgaat ctatagacag ggaaatacag caaattagta agtatattat
    14821 taataacggg tttggcaata gtttttcttg ttgtgatgat atgggtatca ttgaagtatt
    14881 gaagcatact gcagctatct taagtgatga aaagttgaat agtagttgca taaagacatt
    14941 caatgaactt gttaaaaaga aaataaaacc aactataaat aaagaaataa cttatgcaaa
    15001 tgaaaatata tcgttgatga atggtgttgt tggtctagcg tatagtttaa ttaggataag
    15061 tagtgagaaa tttgttccga aaattttatg gttggaataa taatataatt gttgtttata
    15121 ataatatatt aaatttgttt atttggacaa tgtaaaagct tggatattta acaaatgatt
    15181 tttaagttaa gtattcaagt ttttgtatta cacttataaa aattataaat aaaattctat
    15241 aaatagtacc ttgctaatat tttacatgat ttatttatgg tataatatat actatatacg
    15301 ctaaaatctt tttgaaatta tgatttttta attacaacag ggttgagtaa taattataaa
    15361 aattagcaca taaatttaaa gaaaattttc aaaaataaaa atatacatat aaaaaagcag
    15421 aagggggaag gaggactatt tttgaaaaat actagaatca aggatatgag ggatgatgaa
    15481 cttcaggctt acattaaaga aaccaaaaaa gagattgagc agcagttaaa attatatgtt
    15541 aagctaaata atgataagtt atctaataat ggtcaaatac aaaatctcaa gaaaaaagca
    15601 tataatctta aggaagttta tgagtacata aaatgggcga atgataaaat agctattaat
    15661 aataatgttg aatcaagcta tggtactata cctaagcgtg gagagatatg gacctgccaa
    15721 cttggagaaa atattggttc tgaggaaaac aaaataagac ctgcaataat aatacaaaac
    15781 gatactggaa atgaaaaggg accaactaca ataattgttc cgatttctaa taggcctaaa
    15841 aaaatatcaa ctcatattga attaagacct ggggattaca agctcgtaca tggcgaagta
    15901 aataagataa cgggaacaat tttatgtgag caaattaaag ttgtatctaa agctaggttg
    15961 ggaaggcatg tggctactct gaatagtgat ttcgtcaaca aaatattgaa ttctaaatta
    16021 aaaatttcta taaaggtgta atatatttat agaaatgtgc ataaatatag aataaaaaat
    16081 gaaaaatatg ttgataaaat gaagttttaa tgttatcatt aaagtaattg aggtacatac
    16141 ctagatttgc ctaggagact ctctctcata tatttttgct aacttacttg acataggtca
    16201 ggagattata taacatattg tggattggta tagtgccaat ctttttgttt tataaaaaag
    16261 ttttttttat agtaatttat tttattgcat atatagttat taggattcag gaggataaaa
    16321 atggatcaac ttaggtatac catttgtttt ataaaaagag aagatgaagt gcttctttta
    16381 aatagagaaa agcctagctg gatgggaagt tggaatggtg ttggaggaaa gtttcaaaat
    16441 agtgaaactc caatggaatg catacttaga gagatacatg aagagacagg aatgaagttt
    16501 caagaggcca aatttaaagg catagttaca tgggatgaag gagataaaga tattggtggc
    16561 atgtatcttt ttttgataga ggttcctgca aattataatt attctgtacc agtaaaaaca
    16621 cgagaaggga ttttagattg gaaaaagata tcttgggtaa tgaatcctga aaatactgga
    16681 attgcagcaa atgtacctaa atatcttcct aagatgctta aggaagaagg cgaatttaga
    16741 tatcattgtg tttttaaaaa taaaatgctt ctaggggtta acatagaaga gatttgaatt
    16801 aattacataa aaaaggtcca tactgtaatt gtagatatta ttacaaagtt ggaggtcagt
    16861 atggaaccag gcgatatagt tagaatagat gatgataacg aatggaaagg gctttatggt
    16921 gtagttaagt acactaatca atcagaagcc tttatttttt gcgtgcaaaa tccatgttat
    16981 ctttacaagg ctacgactga aaacaatgta gctattgtta ttaaaagatc tgaaagataa
    17041 atgtatcatt tatcatgata aaatttcaca caaacaggat ttggtacgta tatatcagaa
    17101 gttattttac ttaagtttcc gctaacttga tcaacactaa aaattgttag gttacttgaa
    17161 tcttgattag ctgctatcaa taagttacca gaagatgata aatcgaagtc acgaggagaa
    17221 agtccataag tggaagtgtt tgaatttaga gtaaggagtc ctgttgaatt atctacatga
    17281 aagcaggaaa tgctattatg acctctattt gatacataaa gatagtttga attccttgat
    17341 atatggatag cagcacttcc gtttttacct gtgtaatcag taggtaaaca agatacgtac
    17401 tgcaattctt caaaggaacc atctagggga gaatacttta agactataac ctcagagcta
    17461 agttcagtag ctatatatgc aatttttccg tttggatgaa agattatatg tctaggccca
    17521 caaccaggct ttaacttaaa ctcattaaat ctacataaaa tgccatcgtc aaacctataa
    17581 agtactattt tatcggttcc tagatctaca acacaaagaa agtcgttaag tggtgttgtt
    17641 acagcacagt gaacgtgaga agtctcttgt ctttctttat taggaccaaa gccttcatgg
    17701 atcacaaatg aagatacagt atcaatgctt ccatcatttc ttatagggaa aacgtctact
    17761 ctagatgtat gataatttac agaaaacaga tatgaattcg ttttatctaa tgagacataa
    17821 caaggttgtt ttccagaaaa cctttcgggt ggattctcgt aaccaaattt acaatttaag
    17881 agttcaaggt gattatttct atcatctaca taaaatgaag ctgctcctcc taaattgcct
    17941 gacttaataa cagaataagc tgttttatta ttcatattaa aggtgaggta tgttgggttt
    18001 tctatttcgc aagataatat tggagctgtt gtttttctag agtctgaaat aatgttaaaa
    18061 ctataaatgc ctctgctttc tccattagta taagtgccta tataaacctt ttcataattg
    18121 gacatatcaa tacctccttt ttattgtaat tataccataa atacactaat tatttttagt
    18181 tagggtgaac ataataataa aagtaaaaaa agaaaggaaa atatttatgg aggataacta
    18241 taagaatctt aaaattgcag agagaggtgt ccgtatcagt ttaattatat atgtagtact
    18301 ttcaatcttt aagtttttta tgggctattt ttttaagtca gaagcactta aagcagatgg
    18361 aattaatagt tctactgaca taattgcggc tattgcaatt attgtagggc taaaaatagc
    18421 gagaaaacca gcagataaag agcatacata tgggcatttg agggcggaaa ctatatcatc
    18481 acttctagca tcgttaataa tgattgcagt tggagtcgat gttgtgtaca atggagttaa
    18541 aaatactata tttctaagaa atgaaaagcc tgatattaaa gcagctattg tatcgttgat
    18601 ttgtgccagt gttgtgtata cattatatcg ttataatagg tctgtagctg ataaaattca
    18661 cagttcggca cttatggttt cttcaaaaga taatctttca gattcaatgg ttggttttgg
    18721 ttctgcattt gggatatttg catctcaatt cggattccca tggatggatt caataacagc
    18781 agttttagtt ggaataatta tatgtaagac tggttttgga attttccgtg aagcggtaaa
    18841 taatcttaca gatgcgtttg atccagaaaa acttgaaaat ataactaaaa ttataaagga
    18901 tatagatggc gtaagtgata ttaaagatat tagggcaagg gtacatggaa atagtatttt
    18961 attagatgcc attatattag ttgaccctgg tttgagtgtt agggagagtc atgagattac
    19021 ggaagctgta gaaaaaattc ttaaagaaga gtttaatata aggaatgcaa ttattcacgt
    19081 agaaccaaat atagatgagt tgtagtgtat aaatcgagag atattaggct ttgatttata
    19141 tgagaaattg aattagtttt ataaatatat aaaaatggga gtgatttaat atgaaaaaaa
    19201 taatatttgc aggaggatgc ttttggggag ttgaggcata cttcaataca attgatggag
    19261 tcttaaatac aaaggtaggt tatgcaaatg ggaatactga agatccaaca tatgaagatg
    19321 tatgtacaga tagtacagga tatgcagagg cttgctatat agaatatgac gaaaaacaat
    19381 taaaacttga gaaactaata gatgcttact ggaaggtagt agatccaaca ttgaagaata
    19441 gacagggaca cgatgaagga acacaatatc gtacaggaat ttactatgta gatgaagaag
    19501 accttaaagt catattagag tctaaagata aagaacaaga gaaatatgat gctccaattg
    19561 ttacagaaat attgccttta aagaattttt atgatgcaga agaatatcat caaaaatatc
    19621 ttgataagaa tcctaatgga tattgtcata taccaaagga attgttaaaa aagcattaat
    19681 aaatattttt gcgattaaat ggaggcgttt gtatgagaat ttcagttatt gaaccacttg
    19741 gaatttctga agaagaaatt agaagtattg caaaaacaat tacagataga ggacatgaaa
    19801 ttgtaatcta taatgaaaaa agtacagata caaatgtatt aaaagaaaga gtaaaggatt
    19861 cagaggtaat agtgcttgca aatatgccac ttaaggcaga ggtaataaat tctgatagta
    19921 aattaaaaat gatgtctata gcttttacag gagttgatca tgttgaattg agtgctctta
    19981 ataataaaga agtagtggtt tcaaatgctt caggatatag cactgaatca gttactgaat
    20041 taacttttgg acttgttttt tctgtattaa gaaatatagt tcctttggat aaagtaacaa
    20101 gggaaggaaa aacaaaaaat ggcttttctc aaagtgattt aagtggtaaa acctttggag
    20161 taataggcac aggattaata ggtgcttcag tttgtaggat tgcaaaagct tttggctgta
    20221 aggttatagc atatagcaga agtaagaaag aagaactgga agtaattgga gttaattatg
    20281 tgacattaga tgagttgtta gctaaaagtg atgtgatttc tgtccatgtt cctcaaacac
    20341 aagaaacaat aggaatgata agtaaagaga aaattaagct aatgaagaaa acagcaatat
    20401 taataaatgt agcaagaggg ccaattgttg ataatgaggc tttggcagaa gcattggaaa
    20461 atggaactat tgctggagct ggaattgatg tgtttgataa agaacctcct cttgatttag
    20521 ggtataggct tcttaaagca cctaatacag ttgtgttacc gcatgttggt tttgcaacaa
    20581 aagaagccat ggtaagaaga gcgcacataa ccttcgaaaa tatagttaag tggcttgatg
    20641 ggacccctca aaatattgtg aaatattaaa taagcattca tatgatgtac gctgacaata
    20701 ctcaaacggc aaaatcttat aataaataat attccttgta atataaagct tattgtagga
    20761 cat
//
