LOCUS       c00017_NZ_FPJW..       10396 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_FPJW01000006.1 Marinospirillum alkaliphilum DSM 21637, whole
            genome shotgun sequence.
ACCESSION   NZ_FPJW01000006
VERSION     NZ_FPJW01000006
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:13:28
            Original ID  :: NZ_FPJW01000006.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 120054
            Orig. end    :: 130450
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10396
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[125054:125450](+)"
                     /cutoff="20000"
                     /detection_rule="ectoine_synt"
                     /neighbourhood="5000"
                     /product="ectoine"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5396
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="ectoine_synt"
                     /neighbourhood="5000"
                     /product="ectoine"
                     /protocluster_number="1"
     cand_cluster    1..10396
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="ectoine_synt"
                     /kind="single"
                     /product="ectoine"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10396
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="ectoine"
                     /region_number="1"
                     /rules="ectoine_synt"
                     /tool="antismash"
     CDS             1049..1516
                     /locus_tag="ctg17_128"
                     /transl_table=11
                     /translation="MHHLSRSGLSLLLVFLLGWLPIQAQAEMSARDVDLRIDTFDEIDR
                     LFKALRFKVVNQRSTDRQGAMVYSSELVRLGYRLPDLFDHPSPREMFPQSRARPEIWNR
                     KDRYDFLMDEFLDNLEKIHEDLSAGRMSQAGQLIDRTAQGCRRCHNTFRYR"
     PFAM_domain     1145..1507
                     /aSDomain="Cytochrom_C_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01322.22"
                     /description="Cytochrome C'"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg17_128_0001"
                     /evalue="3.70E-12"
                     /label="ctg17_128"
                     /locus_tag="ctg17_128"
                     /protein_end="153"
                     /protein_start="32"
                     /score="47.3"
                     /tool="antismash"
                     /translation="VDLRIDTFDEIDRLFKALRFKVVNQRSTDRQGAMVYSSELVRLGY
                     RLPDLFDHPSPREMFPQSRARPEIWNRKDRYDFLMDEFLDNLEKIHEDLSAGRMSQAGQ
                     LIDRTAQGCRRCHNTFR"
     CDS             1551..2909
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175:pyridine nucleotide-disulfide oxidoreductase
                     (Score: 441.2; E-value: 5.6e-134)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg17_129"
                     /transl_table=11
                     /translation="MSEHDFDLLVIGAGSGGVRAARMAAGRGVRVGIIEDRYWGGTCVN
                     VGCVPKKLYSYAAHFGEDFADAAGYGWNIGTPQFDWPVLRDNRAREILRLNGVYNRLLD
                     NSGVTRIEGRGKILSAHSVQVGEKTYSAERLLITTGSWPYIPDFPGSEHCITSNEVFDL
                     PVFPKRFLVYGGGYIAVEFASIFKGLGAETTLVYRGNKLLRGFDEEVRDFVQEEIGAHG
                     VKLLLEQEIQSLERKADKLLVTLADGSQLTVDAVLCATGRRGNLAGLGLENVGLKANAQ
                     GEIPVDEHFCTEVPSIYALGDVTGGPQLTPVALAEAMVLVHNLYSGEAARVMNYDNIPT
                     AVFCHPNISTVGLSEEKARQVYGEIRVYSTSFRPMRNTLSGNPGRCLMKLVVDDASDKV
                     VGCHVVGPEAGEIVQGMGIAVKAGLTKADFDATLGIHPTSAEELVTLRSLTRR"
     PFAM_domain     1566..2501
                     /aSDomain="Pyr_redox_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07992.16"
                     /description="Pyridine nucleotide-disulphide
                     oxidoreductase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg17_129_0002"
                     /evalue="5.30E-65"
                     /label="ctg17_129"
                     /locus_tag="ctg17_129"
                     /protein_end="317"
                     /protein_start="5"
                     /score="219.7"
                     /tool="antismash"
                     /translation="FDLLVIGAGSGGVRAARMAAGRGVRVGIIEDRYWGGTCVNVGCVP
                     KKLYSYAAHFGEDFADAAGYGWNIGTPQFDWPVLRDNRAREILRLNGVYNRLLDNSGVT
                     RIEGRGKILSAHSVQVGEKTYSAERLLITTGSWPYIPDFPGSEHCITSNEVFDLPVFPK
                     RFLVYGGGYIAVEFASIFKGLGAETTLVYRGNKLLRGFDEEVRDFVQEEIGAHGVKLLL
                     EQEIQSLERKADKLLVTLADGSQLTVDAVLCATGRRGNLAGLGLENVGLKANAQGEIPV
                     DEHFCTEVPSIYALGDVTGGPQLTPVALAEA"
     PFAM_domain     2562..2888
                     /aSDomain="Pyr_redox_dim"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02852.24"
                     /description="Pyridine nucleotide-disulphide
                     oxidoreductase, dimerisation domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg17_129_0003"
                     /evalue="3.80E-34"
                     /label="ctg17_129"
                     /locus_tag="ctg17_129"
                     /protein_end="446"
                     /protein_start="337"
                     /score="117.3"
                     /tool="antismash"
                     /translation="IPTAVFCHPNISTVGLSEEKARQVYGEIRVYSTSFRPMRNTLSGN
                     PGRCLMKLVVDDASDKVVGCHVVGPEAGEIVQGMGIAVKAGLTKADFDATLGIHPTSAE
                     ELVTL"
     CDS             3115..3618
                     /locus_tag="ctg17_130"
                     /transl_table=11
                     /translation="MDTENLRIRKPVADDGVVIHQLIQSCPPLDVNSTYLYLLQCTHFA
                     ETCVVAELNGKVAAFLSGYIKPGNSSTFFLWQVAVGESLRGKGMARRLLDAVLEREACH
                     DVCFLETTITPDNQASWALFRSFARDRQAELTDQVLFSTAELGGQHEPEVLVRIGPFQN
                     KPFA"
     aSDomain        3136..3600
                     /aSDomain="TIGR02406"
                     /aSTool="tigrfam"
                     /description="ectoine_EctA: diaminobutyrate
                     acetyltransferase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg17_130_0001"
                     /evalue="1.90E-61"
                     /identifier="TIGR02406"
                     /label="ctg17_130"
                     /locus_tag="ctg17_130"
                     /protein_end="162"
                     /protein_start="7"
                     /score="204.6"
                     /tool="antismash"
                     /translation="IRKPVADDGVVIHQLIQSCPPLDVNSTYLYLLQCTHFAETCVVAE
                     LNGKVAAFLSGYIKPGNSSTFFLWQVAVGESLRGKGMARRLLDAVLEREACHDVCFLET
                     TITPDNQASWALFRSFARDRQAELTDQVLFSTAELGGQHEPEVLVRIGPFQ"
     PFAM_domain     3232..3489
                     /aSDomain="Acetyltransf_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00583.27"
                     /description="Acetyltransferase (GNAT) family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg17_130_0004"
                     /evalue="5.60E-11"
                     /label="ctg17_130"
                     /locus_tag="ctg17_130"
                     /protein_end="125"
                     /protein_start="39"
                     /score="42.8"
                     /tool="antismash"
                     /translation="QCTHFAETCVVAELNGKVAAFLSGYIKPGNSSTFFLWQVAVGESL
                     RGKGMARRLLDAVLEREACHDVCFLETTITPDNQASWALFR"
     CDS             3679..4989
                     /NRPS_PKS="Domain: Aminotran_3 (28-366). E-value: 5.5e-79.
                     Score: 257.4. Matches aSDomain:
                     nrpspksdomains_ctg17_131_Aminotran_3.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013:aminotransferase class-III (Score: 373.2;
                     E-value: 2.6e-113)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg17_131"
                     /sec_met_domain="Aminotran_3 (E-value: 4.7e-82, bitscore:
                     269.6, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDVNVNSESLERLESEVRTYSRSFPTVFKRARGATLTDENDKDY
                     IDFLAGAGTLNYGHNNPKLKKALLDYIMDDGITHGLDMWTSAKRDFLETLEQVIFKPRG
                     LDYKVQFCGPTGTNAIEAALRIARNTTGRTNIVSFTNAFHGVTLGALATTANSKFRHAA
                     AMPTAGVSFMPYCGYMDGDSSSLAFLEKTLTDNSSGVDYPAAILLETVQGEGGINVASI
                     EWLQGIEKICRKHGILLIVDDIQAGCGRTGKFFSFEHAGLKPDIVTSSKSLSGYGLPFA
                     AVFMKPELDQWKPGEYNGTFRGNNLAFVTATTAMREYWRNDDLARDVTRKGKIVEHRFK
                     QLARAYQAAGIEASERGRGLMRGLDILQGDLADEIVADCFENGLVIETSGPEGQVVKCL
                     CPLLISDDELNKGLDILEQAVKRQLDRLNSNQTRKSA"
     aSDomain        3709..4941
                     /aSDomain="TIGR02407"
                     /aSTool="tigrfam"
                     /description="ectoine_ectB: diaminobutyrate--2-oxoglutarate
                     aminotransferase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg17_131_0002"
                     /evalue="1.40E-198"
                     /identifier="TIGR02407"
                     /label="ctg17_131"
                     /locus_tag="ctg17_131"
                     /protein_end="421"
                     /protein_start="10"
                     /score="657.5"
                     /tool="antismash"
                     /translation="LERLESEVRTYSRSFPTVFKRARGATLTDENDKDYIDFLAGAGTL
                     NYGHNNPKLKKALLDYIMDDGITHGLDMWTSAKRDFLETLEQVIFKPRGLDYKVQFCGP
                     TGTNAIEAALRIARNTTGRTNIVSFTNAFHGVTLGALATTANSKFRHAAAMPTAGVSFM
                     PYCGYMDGDSSSLAFLEKTLTDNSSGVDYPAAILLETVQGEGGINVASIEWLQGIEKIC
                     RKHGILLIVDDIQAGCGRTGKFFSFEHAGLKPDIVTSSKSLSGYGLPFAAVFMKPELDQ
                     WKPGEYNGTFRGNNLAFVTATTAMREYWRNDDLARDVTRKGKIVEHRFKQLARAYQAAG
                     IEASERGRGLMRGLDILQGDLADEIVADCFENGLVIETSGPEGQVVKCLCPLLISDDEL
                     NKGLDILEQAVK"
     aSDomain        3709..4953
                     /aSDomain="TIGR00709"
                     /aSTool="tigrfam"
                     /description="dat: 2,4-diaminobutyrate 4-transaminase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg17_131_0003"
                     /evalue="3.30E-144"
                     /identifier="TIGR00709"
                     /label="ctg17_131"
                     /locus_tag="ctg17_131"
                     /protein_end="425"
                     /protein_start="10"
                     /score="478.7"
                     /tool="antismash"
                     /translation="LERLESEVRTYSRSFPTVFKRARGATLTDENDKDYIDFLAGAGTL
                     NYGHNNPKLKKALLDYIMDDGITHGLDMWTSAKRDFLETLEQVIFKPRGLDYKVQFCGP
                     TGTNAIEAALRIARNTTGRTNIVSFTNAFHGVTLGALATTANSKFRHAAAMPTAGVSFM
                     PYCGYMDGDSSSLAFLEKTLTDNSSGVDYPAAILLETVQGEGGINVASIEWLQGIEKIC
                     RKHGILLIVDDIQAGCGRTGKFFSFEHAGLKPDIVTSSKSLSGYGLPFAAVFMKPELDQ
                     WKPGEYNGTFRGNNLAFVTATTAMREYWRNDDLARDVTRKGKIVEHRFKQLARAYQAAG
                     IEASERGRGLMRGLDILQGDLADEIVADCFENGLVIETSGPEGQVVKCLCPLLISDDEL
                     NKGLDILEQAVKRQLD"
     PFAM_domain     3745..4938
                     /aSDomain="Aminotran_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00202.23"
                     /description="Aminotransferase class-III"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg17_131_0005"
                     /evalue="4.00E-80"
                     /label="ctg17_131"
                     /locus_tag="ctg17_131"
                     /protein_end="420"
                     /protein_start="22"
                     /score="269.6"
                     /tool="antismash"
                     /translation="RSFPTVFKRARGATLTDENDKDYIDFLAGAGTLNYGHNNPKLKKA
                     LLDYIMDDGITHGLDMWTSAKRDFLETLEQVIFKPRGLDYKVQFCGPTGTNAIEAALRI
                     ARNTTGRTNIVSFTNAFHGVTLGALATTANSKFRHAAAMPTAGVSFMPYCGYMDGDSSS
                     LAFLEKTLTDNSSGVDYPAAILLETVQGEGGINVASIEWLQGIEKICRKHGILLIVDDI
                     QAGCGRTGKFFSFEHAGLKPDIVTSSKSLSGYGLPFAAVFMKPELDQWKPGEYNGTFRG
                     NNLAFVTATTAMREYWRNDDLARDVTRKGKIVEHRFKQLARAYQAAGIEASERGRGLMR
                     GLDILQGDLADEIVADCFENGLVIETSGPEGQVVKCLCPLLISDDELNKGLDILEQAV"
     aSDomain        3763..4776
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg17_131_Aminotran_3.1"
                     /evalue="5.50E-79"
                     /label="ctg17_131_Aminotran_3.1"
                     /locus_tag="ctg17_131"
                     /protein_end="366"
                     /protein_start="28"
                     /score="257.4"
                     /tool="antismash"
                     /translation="FKRARGATLTDENDKDYIDFLAGAGTLNYGHNNPKLKKALLDYIM
                     DDGITHGLDMWTSAKRDFLETLEQVIFKPRGLDYKVQFCGPTGTNAIEAALRIARNTTG
                     RTNIVSFTNAFHGVTLGALATTANSKFRHAAAMPTAGVSFMPYCGYMDGDSSSLAFLEK
                     TLTDNSSGVDYPAAILLETVQGEGGINVASIEWLQGIEKICRKHGILLIVDDIQAGCGR
                     TGKFFSFEHAGLKPDIVTSSKSLSGYGLPFAAVFMKPELDQWKPGEYNGTFRGNNLAFV
                     TATTAMREYWRNDDLARDVTRKGKIVEHRFKQLARAYQAAGIEASERGRGLMRGLDI"
     PFAM_domain     5001..5381
                     /aSDomain="Ectoine_synth"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06339.14"
                     /description="Ectoine synthase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg17_132_0006"
                     /evalue="1.20E-53"
                     /label="ctg17_132"
                     /locus_tag="ctg17_132"
                     /protein_end="127"
                     /protein_start="0"
                     /score="180.8"
                     /tool="antismash"
                     /translation="MIVRNLEEARKTDRFVVAENGNWDSTRLVLADDGMNHSFHITRIY
                     AGTETPIHYKHHLETVYCIEGEGEVETVADGKIWPIRPGDVYVLDKHDQHLLRASKTMT
                     VACVFYPAITGTEKHREDGSYAP"
     CDS             5001..5396
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ectoine: ectoine_synt"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg17_132"
                     /sec_met_domain="ectoine_synt (E-value: 1.7e-43, bitscore:
                     141.5, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIVRNLEEARKTDRFVVAENGNWDSTRLVLADDGMNHSFHITRIY
                     AGTETPIHYKHHLETVYCIEGEGEVETVADGKIWPIRPGDVYVLDKHDQHLLRASKTMT
                     VACVFYPAITGTEKHREDGSYAPADEG"
     CDS             complement(5519..7078)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:diguanylate cyclase (Score: 169.7; E-value:
                     2.4e-51)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg17_133"
                     /transl_table=11
                     /translation="MQQVSDSQLPPTLIKKLQDCRTLPSLPAIVVSILELARTPTAGTL
                     ELANLVAKDPSLSAKLLAAANSAFYAGSELKTLQQAVNRIGMEGALSLSLSFGLAFRGT
                     RDSNGMDLDNFWKRALISGMVVRELQRLMNLRFDVETTYLAAVLQDIGMLALNEMDPDI
                     YGVIYHSARSHRQLASFEEREYGTNHTQVGHWLCSRWGLPEKYTLPLLNSHQLPKEIDK
                     TNAAQRVLALSGLMADPWLSSNQEMAMTLAYQASQDYLQMDERQFSHLLLHLQDKLPDI
                     ARLFEIKAPAQIDTFNLLQEAKHLLVERNLRMMQKLAQQQQEIDELRRNSEKLQEQLKK
                     DPLTGIFNRQYTEKELQQHFMAIQQSGGSLAVVFIDLDYFKTLNDQYGHALGDSALKAF
                     ATALEQELESGCIAGRYGGEEFVALLPGFNQDEALAFARRLQEHLASTPLLSHNKEDIY
                     VSASMGIAVQQLRDNAQPVFADADELVSAADQAMYNAKRTGRNRILLFTSGGQSQDLSE
                     NS"
     aSDomain        complement(5567..6079)
                     /aSDomain="TIGR00254"
                     /aSTool="tigrfam"
                     /description="GGDEF: diguanylate cyclase (GGDEF) domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg17_133_0004"
                     /evalue="2.00E-45"
                     /identifier="TIGR00254"
                     /label="ctg17_133"
                     /locus_tag="ctg17_133"
                     /protein_end="504"
                     /protein_start="333"
                     /score="152.4"
                     /tool="antismash"
                     /translation="LQEQLKKDPLTGIFNRQYTEKELQQHFMAIQQSGGSLAVVFIDLD
                     YFKTLNDQYGHALGDSALKAFATALEQELESGCIAGRYGGEEFVALLPGFNQDEALAFA
                     RRLQEHLASTPLLSHNKEDIYVSASMGIAVQQLRDNAQPVFADADELVSAADQAMYNAK
                     RTGRNRIL"
     PFAM_domain     complement(5573..6061)
                     /aSDomain="GGDEF"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00990.23"
                     /description="Diguanylate cyclase, GGDEF domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg17_133_0008"
                     /evalue="5.60E-42"
                     /label="ctg17_133"
                     /locus_tag="ctg17_133"
                     /protein_end="502"
                     /protein_start="339"
                     /score="143.3"
                     /tool="antismash"
                     /translation="KDPLTGIFNRQYTEKELQQHFMAIQQSGGSLAVVFIDLDYFKTLN
                     DQYGHALGDSALKAFATALEQELESGCIAGRYGGEEFVALLPGFNQDEALAFARRLQEH
                     LASTPLLSHNKEDIYVSASMGIAVQQLRDNAQPVFADADELVSAADQAMYNAKRTGRNR
                     "
     PFAM_domain     complement(6434..7012)
                     /aSDomain="HDOD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08668.14"
                     /description="HDOD domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg17_133_0007"
                     /evalue="1.30E-39"
                     /label="ctg17_133"
                     /locus_tag="ctg17_133"
                     /protein_end="215"
                     /protein_start="22"
                     /score="135.8"
                     /tool="antismash"
                     /translation="LPSLPAIVVSILELARTPTAGTLELANLVAKDPSLSAKLLAAANS
                     AFYAGSELKTLQQAVNRIGMEGALSLSLSFGLAFRGTRDSNGMDLDNFWKRALISGMVV
                     RELQRLMNLRFDVETTYLAAVLQDIGMLALNEMDPDIYGVIYHSARSHRQLASFEEREY
                     GTNHTQVGHWLCSRWGLPEKYTLPLLNSHQ"
     CDS             complement(7161..8084)
                     /locus_tag="ctg17_134"
                     /transl_table=11
                     /translation="MITSFITHQDCALHDMGPWHPESPLRLNAIIDQLKLSGLMNQLMQ
                     YSARPVTEEQLHRAHPRAHIRSLQLSLPQEGFTAIEDETLLGPRSLDAAGMAAGAVVRG
                     VEQIFKNQADNVFCAVRPPGHHAERVESMGFCFYNNVAVGALHALEHYKLDRVAIVDFD
                     VHHGNGTVDVFRNDPRVLVCSSFQHPFYPWRYTDHQGDHIINTPLDAHTGSLAFRKAIE
                     ASWLPALQAFKPQLILVSAGFDAHREDPMGELNLEDDDYHWITTLLMDQARIHAQGRLV
                     SVLEGGYDLNSLARSVHRHIEALQGL"
     PFAM_domain     complement(7173..8027)
                     /aSDomain="Hist_deacetyl"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00850.21"
                     /description="Histone deacetylase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg17_134_0009"
                     /evalue="5.70E-84"
                     /label="ctg17_134"
                     /locus_tag="ctg17_134"
                     /protein_end="304"
                     /protein_start="19"
                     /score="282.2"
                     /tool="antismash"
                     /translation="HPESPLRLNAIIDQLKLSGLMNQLMQYSARPVTEEQLHRAHPRAH
                     IRSLQLSLPQEGFTAIEDETLLGPRSLDAAGMAAGAVVRGVEQIFKNQADNVFCAVRPP
                     GHHAERVESMGFCFYNNVAVGALHALEHYKLDRVAIVDFDVHHGNGTVDVFRNDPRVLV
                     CSSFQHPFYPWRYTDHQGDHIINTPLDAHTGSLAFRKAIEASWLPALQAFKPQLILVSA
                     GFDAHREDPMGELNLEDDDYHWITTLLMDQARIHAQGRLVSVLEGGYDLNSLARSVHRH
                     IEAL"
ORIGIN
        1 ttacaaatcc ggtccggtac cgggtgccga ggaagccggc ccgccaccgg atgaacccca
       61 accggtgcgt tttgcagaaa acaccaatcc ttttgcggag ttggatgagc tgggttatca
      121 gctcaaaaaa ctctttgaac gcattgaaga acaatctgcc aaacccggtg aagttgagcg
      181 caaaacctat gaaatggctg ctcagattca aggtctggtg cagcttaaca gtgatgcagt
      241 gctgggtgcg gtgcacttga accgtgaaca tgcctacatc atccagcacc ccttgcacgt
      301 cactgttatg gcggcgctga ttgcccgcac actcaatgtt ccccagcgta cccagctttc
      361 catgctggct gcagccttga cccagaatgt gggcatgaat gcctaccaga tgcgattgca
      421 tgcccaggca gccccactgg atgacaaaca aagggcgcag gttgatcagc atcctctgga
      481 aggggtgaaa atgctcaatg cggccggagt gcatgacaac ctctggctgc aaattgtgtt
      541 tcagcatcat gaaaaagcca atggcaaggg ttatcccaag gggcttaaag gcaatcaaat
      601 ccggccggaa gcgcgtattg ttgcgctggg tgatgtttac tcggcgctgg tcagtgggcg
      661 tccccatcgt cccggactga gtgcccagca aagcctgcgc tcaatttttc ttgagcgggg
      721 acagcagttt gatcccaagc tcagtatggt gtttctgaat gaactgggtc tgtatccacc
      781 gggtgcctgc gtgcgtctgc gtaatgggga agttggggtg gttgtgcgtc gtacttccga
      841 tagccgtgca ccgatggtca ccagcgtgat ggatgaccgt ggacagctgt tcatgcgttt
      901 gcaggagcgg gataccagtg agtttgacta taatgtcatg gcctctgtgc atcctcagca
      961 tttgccaaaa ttgaacccaa ccctgttgtg gggaatcaaa ctcaagagga tcggctgata
     1021 tactgaaaaa aatagacgga ggatactgat gcaccacttg tcccgcagtg gcttatcact
     1081 gttgttagtg tttctgctgg gttggttgcc gatacaggct caagctgaaa tgtctgcaag
     1141 agatgtggat cttcgcatcg atacctttga tgaaatcgat cgcttattca aagcactgcg
     1201 tttcaaggtt gtgaatcagc gcagtactga tcgtcagggt gccatggttt actccagtga
     1261 actggtgcgc ctgggttacc gcctcccgga tttgtttgat catccttctc cccgtgaaat
     1321 gtttcctcag agccgtgctc gtccggaaat ctggaatcgt aaagaccgtt atgacttcct
     1381 gatggatgag tttctggaca atcttgaaaa aatccatgaa gacctgagtg ccggccgcat
     1441 gagtcaggcg ggtcagttga ttgatcgtac tgctcagggc tgcagacgtt gtcataacac
     1501 tttccgttac agataatggc tgctgccatt tttcataacg ggaagacctg atgagtgaac
     1561 atgattttga cctgctggtg attggtgccg gatccggtgg tgtgcgtgct gcgcgtatgg
     1621 cagcaggtcg gggtgtaagg gttggcatca ttgaagaccg ttactggggc ggaacctgcg
     1681 ttaatgttgg ctgtgtaccc aaaaaactct actcctacgc cgcccacttc ggggaagatt
     1741 ttgctgatgc agccggttat ggctggaaca tcggtacacc gcagtttgac tggccggtat
     1801 tgcgtgataa ccgtgccagg gaaatcctcc gattgaatgg ggtgtataac cgcctgctgg
     1861 acaacagtgg tgtgacccgt atcgaagggc ggggcaagat cctttctgct cattccgttc
     1921 aggtgggtga aaagacctat agcgcggaac gcctgctgat taccactggc tcctggcctt
     1981 acattccgga ttttcccggt tcagagcact gcatcacttc caatgaagtg tttgacctgc
     2041 cggtgtttcc gaagcgcttc ctggtgtacg gcggtgggta cattgcggtg gaatttgctt
     2101 cgatctttaa aggtctgggt gctgaaacca cactggtgta ccggggtaac aagttgttgc
     2161 gtggttttga tgaagaagta cgtgactttg ttcaggaaga aatcggtgct catggcgtta
     2221 agctgttgct ggagcaggag attcaaagcc ttgaacgcaa ggcggacaaa ctgctggtga
     2281 cattggctga tggttcacag ttaaccgtgg acgcggtgct ttgtgccaca ggtcgacgcg
     2341 gcaacctggc gggcctgggt cttgagaatg ttggcttgaa ggccaatgca cagggtgaaa
     2401 tccccgttga tgaacatttt tgtaccgagg tgccgagcat ttatgcgctg ggtgatgtca
     2461 ccggtggccc gcaattgaca cctgtggcac tggctgaagc catggtcctg gtgcataacc
     2521 tctacagcgg tgaagctgca cgggtgatga attatgacaa cattcccact gcagtgtttt
     2581 gccaccccaa tattagtaca gtggggctga gtgaagaaaa agcacgtcag gtttatggcg
     2641 aaatccgggt ttattccacc agcttcagac ccatgcgtaa taccctgtct ggtaatcctg
     2701 gtcgttgcct gatgaaactg gtggtggatg atgccagtga caaggtggtt ggttgccatg
     2761 ttgtgggtcc ggaagccggt gaaatcgtac agggaatggg cattgcagtg aaagctgggc
     2821 tgaccaaggc tgattttgat gccacccttg gcattcaccc cacctctgct gaagagttgg
     2881 tgaccctgcg tagcctgaca cgacgttaat cactggctgt ccaggcacga actgcagaaa
     2941 gtgaagtgac cccgccctgg cggggttttt tgttttatgg cagctaccgg gttgggctga
     3001 ttcggagaat gataattaaa aattatgatt taaccatttc ttcataatcc aaaatttgat
     3061 ttttgggtgg tttctgttat cctgtatgca tcctggatag agaccacaac ttatatggat
     3121 actgaaaatc tacgtatcag aaagcctgta gctgatgatg gtgttgttat tcatcagctg
     3181 attcagagct gccctccgct ggatgtcaat tcgacctacc tttatttgct gcagtgcact
     3241 cattttgctg aaacctgcgt tgttgccgag ctgaacggca aggttgctgc ttttttatcc
     3301 ggctacatca agccgggtaa cagttcgaca ttttttctct ggcaggtagc agtgggtgag
     3361 tcactgcgag gcaagggtat ggccaggcgc ttgctggatg cagtgctgga gcgggaggca
     3421 tgccatgacg tgtgttttct tgaaacgacc attactccgg acaatcaggc ctcctgggcg
     3481 ttatttcgca gttttgcgcg ggatcgccag gctgaactga ccgatcaagt gctgttcagt
     3541 accgctgagt tgggtggtca gcatgaaccg gaagtactgg tcaggatcgg gcccttccag
     3601 aataagccct ttgcttagtg cccggtaagc tcattgatga cccacttcac cgattaaaaa
     3661 acagacaggt aaaacaccat gactgacgta aacgttaact ctgaatccct ggaacgcctg
     3721 gaatctgaag ttcgcaccta cagccgttcc tttccaaccg ttttcaagcg tgcacgtggt
     3781 gccaccctga cggatgaaaa cgacaaggat tacattgatt ttctggcggg tgccggcacg
     3841 ttgaattatg gccacaacaa tccaaagctg aaaaaagccc tgctggatta catcatggat
     3901 gacggtatca cccatggtct ggatatgtgg acgagtgcca aacgtgattt tctggaaacc
     3961 ctggagcagg tgatctttaa gcccagaggg ctggattaca aggtacagtt ctgtggcccg
     4021 accggaacca atgccattga ggctgccctg cggattgccc gcaacactac cggtcgcacc
     4081 aatatagttt ccttcaccaa tgcatttcat ggtgtgactc tgggtgctct ggccaccacg
     4141 gccaacagca agttccgcca tgcagcagca atgcccactg ccggcgtttc cttcatgcct
     4201 tactgcggtt acatggatgg cgactcatcc agtctggcct ttctggaaaa gactctgact
     4261 gataactcca gtggagtgga ttatcctgca gcgatcctgc tggaaaccgt acagggtgaa
     4321 ggcggcatta atgtggcttc cattgaatgg ttgcagggca tcgaaaaaat ctgtcgcaag
     4381 catggcattc tgctgattgt cgacgacatt caggcgggct gtggccgtac cggcaagttc
     4441 ttcagttttg aacatgccgg gttgaagccg gatattgtca ccagctccaa atcgctgtcc
     4501 ggttatggat tgccctttgc agcagtgttc atgaagccgg aactggatca gtggaagcca
     4561 ggtgaataca acggtacttt cagaggcaat aacctggcct ttgtcacggc caccactgcg
     4621 atgcgtgaat actggcgtaa tgatgacctg gcgcgtgatg tcactcgcaa gggcaagatt
     4681 gtcgagcacc gcttcaaaca gctggctcgt gcttatcagg cagccggtat tgaggcctcc
     4741 gaacgggggc gtggcctgat gcgtggactg gatatcttgc agggtgatct ggccgacgag
     4801 attgtggctg actgctttga aaatggcctc gtcatcgaaa ccagcgggcc agaagggcag
     4861 gtggtcaaat gcctgtgtcc gctgctgatc agtgatgatg agctgaacaa gggactggat
     4921 attcttgagc aggctgtaaa acgccagttg gacaggctga acagcaatca gacccgtaag
     4981 tcagcctgag gagtggtggc atgatagtca gaaacctgga agaagcccgc aagacagatc
     5041 ggtttgtggt ggctgaaaac ggtaactggg acagcacccg gctggtgctg gcggatgatg
     5101 gcatgaacca ctcattccac atcacccgaa tttacgctgg aaccgagact cccatccatt
     5161 acaagcacca cctggaaacg gtttattgca ttgaaggtga gggcgaagtg gaaaccgtgg
     5221 ctgatggtaa aatctggccg attcggcccg gtgatgtgta tgtgctggat aaacacgatc
     5281 aacacctgct gcgtgccagt aaaaccatga cggtggcttg tgttttttat ccggcaatca
     5341 ccggtacgga aaagcaccgt gaggatggtt cttacgcgcc ggcagatgaa ggctaatcct
     5401 gccgccaagt gataaaaatg gtgtgataaa agctgtgaaa taaaaaagag gccatgtagg
     5461 gcctcttttt tatatagggt tcttatgtaa gcttcctggc tgttttcact gagaactctc
     5521 agctgttttc actgagatcc tggctttgtc cgccagaggt aaacaacagg atgcgattac
     5581 gccctgtgcg tttggcattg tacatggcct gatctgcagc actgaccagc tcatcagcgt
     5641 cagcaaaaac gggttgggca ttatccctta attgctgaac agcaatgccc atggatgcgg
     5701 acacatagat atcttccttg ttgtggctta gcaggggggt actggccagg tgctcttgca
     5761 ggcgccttgc aaaagccagt gcctcatcct ggttaaaacc gggcaacaag gcaacaaact
     5821 cttcgccacc ataacggcca gcaatgcagc cgctttccaa ttcctgctcc agtgccgtag
     5881 caaaggcttt taacgctgag tcacccagag catgaccata ttgatcattc agggttttga
     5941 aataatccag gtcaatgaaa acaaccgcca gagaaccacc ggattgctga atcgccataa
     6001 agtgctgttg caattctttt tcggtgtact ggcggttaaa aatacctgtc agcggatctt
     6061 ttttgagctg ttcctggagt ttttcagaat tacggcgcag ttcgtcaatt tcctgctgct
     6121 gctgcgccag tttctgcatc atgcgcaggt tgcgctccac cagtaggtgt ttggcttcct
     6181 gcagcaggtt aaaggtgtcg atctgtgccg gtgccttgat ttcaaacagg cgggcaatat
     6241 caggtaattt gtcttgcaag tgcagcaaca gatgagagaa ctggcgctca tccatctgca
     6301 gataatcctg gctggcctgg taggccagtg tcatcgccat ctcctgattg gaagacaacc
     6361 aggggtcagc catcaagccg gataaagcca atacacgttg ggctgcattg gtcttgtcta
     6421 tttctttagg cagttgatgg ctgttcagca gcggcagagt gtacttttcc ggtaagcccc
     6481 agcggctgca taaccagtgg cctacctggg tgtggttggt accgtattca cgctcttcaa
     6541 aagaagccag ttggcggtgg gagcgggcac tgtgataaat cacaccgtaa atatcagggt
     6601 ccatctcgtt taatgccagc atgccaatgt cttgcagcac tgccgccaga taggtggttt
     6661 caacatcaaa gcgcaggttc atcaggcgtt gcagttcacg caccaccatg ccgctgatca
     6721 gggctcgctt ccagaagttg tccagatcca tgccgttgct gtcacgggtg ccacgaaagg
     6781 ccagcccgaa gctgagcgac aaggacaggg caccttccat gccaatacga ttaaccgcct
     6841 gttgcagcgt ttttaattcg ctgcctgcat aaaaggcaga gttggctgcg gccagcagtt
     6901 tggcgctgag ggatggatcc ttggcaacca gattggccag ctccagggtt ccggctgtgg
     6961 gtgtgcgcgc cagctcaaga atgctcacca caatggctgg cagggagggc agggttctgc
     7021 aatcctgaag tttcttgatc agggtcggcg gcaattgaga gtcactgacc tgttgcatgc
     7081 atgggtatcc ttgatcgacg ttagtcgcga tgggttccac tatactccag tgcaggcaaa
     7141 tccaaaagtc atccggtgcg tcagaggccc tgcagcgcct ctatgtgccg gtgaactgat
     7201 cgcgccaggg agttaaggtc ataaccccct tccagcacgg ataccagtcg cccttgtgca
     7261 tggatgcggg cctgatccat caatagagtg gtgatccagt gataatcgtc atcttccaga
     7321 ttcagttcac ccatgggatc ttcacgatgt gcatcaaaac cggcagatac cagaatcagt
     7381 tggggtttga atgcctgcag ggcaggcagc caactggctt caatggcttt acggaaagcc
     7441 aggctaccgg tatgggcgtc caggggtgta ttgatgatgt gatcgccctg gtgatctgtg
     7501 taacgccagg gataaaaggg gtgctggaag ctggagcaga ccagcacacg cggatcatta
     7561 cggaatacat caaccgtacc gttaccgtgg tgtacgtcga aatcaacaat ggctacacga
     7621 tccagcttgt aatgttccag tgcatgaagc gcaccaacgg ctacattgtt gtaaaaacaa
     7681 aagcccatgc tttccacgcg ttcagcatgg tgccccggtg ggcgcacggc acagaacaca
     7741 ttgtcagcct ggttcttgaa gatctgttca acaccgcgca cgacagcacc ggcagccatg
     7801 ccagcggcat ccagtgagcg cggacccagt agggtttcat cttcaatggc ggtgaaacct
     7861 tcctgtggca gactcagttg taatgagcgg atgtgtgctc tggggtgagc acgatgtagc
     7921 tgttcttcag tgaccggtcg ggcagagtac tgcatcagct gattcatcaa accgctgagt
     7981 ttaagctgat caatgatggc attcaggcgc agagggcttt ccggatgcca gggccccatg
     8041 tcatgaaggg cgcagtcctg atgagtgatg aaagatgtga tcatggctcc gcctgctatt
     8101 cgttactttt tgttattcag tttaatcttg tttcgctttg ggggatactg ggcaatggtc
     8161 gaagaatctg gatgggctgg agaaacaagg tgagcacaag gtttctgcgt tatttttttg
     8221 agccacgtac cctggcagtg attggtgcct cggaaaaaaa cttcagcctg ggtgggcagg
     8281 tggtggttaa cctgttggac gctgcttttc cgggccgcgt atgggtcgtg aaccctaagg
     8341 gttacatccg tgtgcatggc tgtgaatgtt atgctcatgt acgtgattta ccggaggtac
     8401 ctgatctggc cgtggtctgt acaccggccg atgttgctcc cgatgtggtg gccgagctgg
     8461 gccgctttgg tgtcaaggca gcattggtgc tgacttccgg ccaggggcac cgcagaacca
     8521 attacaaggt gcgactgctg gaagccgccc agagctcggg catacgggtc atggggcctg
     8581 agtgcatggg gattctggta ccctcccgca agctgaatgc cagttatgca ccacagaaca
     8641 tcaagcctgg caaggtggct tatatcggtc aatccggcat gctgggcaat gccatcattg
     8701 actgggccaa cgggcgcggc ataggttttt cccatctgat taccctgggc gacagtgttg
     8761 acgtgcgcct ggcggatgtc attgattaca tcaaccgttt ttccaatgcc caggcgattt
     8821 tgttgcacct ggaaaatgtg ccggattccc gtcacttcat gaccgcagtg cgtgaagctt
     8881 cgcgcaacaa gttggtgctg gcgattaaat caggtcgcac cgcggaagct cagggcgacc
     8941 cggatcttta tacccccggt ttgatcaacc gcgaccctgt gtatgatgca gccttctccc
     9001 gtgcgggtat ggtcagggtg cataacagtg aagagttgtt tgatgccttg gaaaccctga
     9061 cccgcatgcg tccggtaaga ggggacaagc tggccattgt cagcaatggg cttggtccga
     9121 gcatgctggc cgtggatagg ttgatacacc agggcgggca gttggccccc ctgacggaag
     9181 caacccgcga gcggttgcgc gcctggttgc ccagtgatga gcatcgcatc aatccgctgg
     9241 atatcggtgg tggtgcgaca ccccagcagt ttgttgatgc catccagatc gtttctgaag
     9301 acccggaagt ggatgcagta ttggtggtgc atgcacccac tcgactggca cccagtgaag
     9361 ccaccgcact ggcggtgatt gccaataaaa aaagctacaa acgtaatctg ctgaccagtt
     9421 ggatggggct ggatcatgcc tttccagccc gtcatgagtt caatctggct ggaataccca
     9481 cctacctgtc accggaaaaa gcagtgcaag cctttatgca cctggtgaat tatcagcgca
     9541 accagttgtt gctgcaggaa acgccaccca cgctgccgtt tgaaacctct caggaagcac
     9601 gcaaccaggt gaggcagttg gttgaatcag tggtggcgga agggcgtctg catctgagtc
     9661 atgaagaaac agcgcagttg ctgaaagcct atgccattga catggcaccg accttttacc
     9721 cgaaaacacc ggaacaggcc ggtttgctgg caaaacagat tgaaggcagc aaggctttaa
     9781 aaatcaatca tgccaccaac tcctgtccgt ttgtgtaccg caagcacccg cacaaggtct
     9841 ctgccgggtt gttacatgac ctggaaacac cggaggatgt gcgtctgggt gcagaaaaac
     9901 tgctggcaaa agtgcaggaa aagtttccgc acagcccggt gcattctttt gtgctgcagc
     9961 ccatgcagcg cggcaaacac tccatgcagc tgaaccttgg cattacccgt gatccggtat
    10021 tcggcccggt gattttgttc ggtattggtg gttacaaggt caatatcctg ctggatcggc
    10081 agattgccct gccaccactg aacatgaccc tggcgcagga tctggtgaaa cgcagtcatg
    10141 ccggtcgttt gatccaggag cacagcaatc atcctgagca ggatctggag cgtattggtg
    10201 tgctgctggt gaaactctcc cagctttgtt cagacatccc tttgattcgc ggcctggaaa
    10261 tcaatccact gttactgaat cgacgtgaaa tgtttgccat tgatgtgcag tgtgatctgg
    10321 gtgatccggc ttatcatgcc atcatgcctt acccggaaga tctgcggaaa aaggtggcac
    10381 tcaaggatgg tcggga
//
