LOCUS       c00036_NZ_CCYH..       13709 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CCYH01000036.1 Candidatus Soleaferrea massiliensis AP7, whole
            genome shotgun sequence.
ACCESSION   NZ_CCYH01000036
VERSION     NZ_CCYH01000036
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:16:21
            Original ID  :: NZ_CCYH01000036.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 189982
            Orig. end    :: 203691
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13709
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[199982:201593]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11611
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..13709
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13709
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /tool="antismash"
     CDS             1465..4755
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 81.8; E-value: 8.8e-25)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg36_146"
                     /transl_table=11
                     /translation="MMTEEIRNEVEAFARKILYRYFCESDVDFLISTFAPDIVWLGAGK
                     EQKAEGKDAVAAQFLAGRSDLAPCDMSGERYVSRELADGVYLCEGDSWLQPKPETGLYF
                     RTHQRVTFIFKRTEDGFQCLHIHNSVDYSDIQDGELFPAQAAQEAYRRMQETLNKQNRQ
                     IELMLSQLPGGMLICQADEDFTVKWISESLCALLGYENAQEYLSSACGRSSGFILEEDL
                     QQVRDYVNRKLQSDGTYYCEYRVKCKDGSVCWISDLGKRVSDPDGEEVIYCFISDITIR
                     KSRELQIAKANEEVRRQADFLNQLYTSIPCGILQFTTDPEHLTVNINRMVWEFYGYESE
                     EAFNREIRSPIQLILEKDRPGLVEKIDQLRPGEGALNYTRMVQKMDGTSAWINVIMERL
                     TNVEGLDVIQAIFTDVTQVKQCQLEQERERLIENRSLRAATCTAYPLIMSVNLTQDTYN
                     CFIEEQNCPLEHRQGSFDEMVARSIPDIYPSYREDFAKTFDRKEILRRFAAGEREIYME
                     LQQMGADGKYHWISVHLIYVDNPIGGDVLAIDLVKVLDHQRQEQARQEQLLRDALSAAR
                     AANNAKSDFLSRMSHDIRTPMNAIIGMSAIGQMKLDDPARVRDCFQKIDTSSRFLLSLI
                     NDILDMSKIENGKMSLTHEQFDFTELFDEIISIIYPQTLDLRLTFEVHHQEPIEKYYIG
                     DALRIKQILMNLLSNTLKFTPPGGRITVEVKELRRTNGFAYLCFQVKDTGIGMSEDFQQ
                     KMFTAFEQESQEKARDKVGSGLGLTIVHNLVQMMNGTIQVQSGKGKGTVFQVTLPLELA
                     EDNEAAERQRKSKELLRDMQVLVVDDDALIGEQVAQMMSDIGAVSKWVDSGEKALEEVA
                     ASLRLGRTYDVAMIDWKLPGMDGIETTRRMRDLVGPDTTIIIISAYDWSSIQEEARAVG
                     ADYFMSKPLFRSTIYQTFNQLGHDSPLSGKTSAPAHVGDCFSNQRVLLVEDNDLNLEVA
                     QSLLQMSGLQVDTAENGKKAVERFEDAPVGHYMAILMDVRMPVMDGIEATRVIRSLKRA
                     DARTVPILAMTANAFDEDRQLAFAAGMSGYLVKPLDIHVLLDELKKLQ"
     aSDomain        1993..2319
                     /aSDomain="TIGR00229"
                     /aSTool="tigrfam"
                     /description="sensory_box: PAS domain S-box protein"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg36_146_0001"
                     /evalue="3.40E-11"
                     /identifier="TIGR00229"
                     /label="ctg36_146"
                     /locus_tag="ctg36_146"
                     /protein_end="285"
                     /protein_start="176"
                     /score="41.3"
                     /tool="antismash"
                     /translation="ICQADEDFTVKWISESLCALLGYENAQEYLSSACGRSSGFILEED
                     LQQVRDYVNRKLQSDGTYYCEYRVKCKDGSVCWISDLGKRVSDPDGEEVIYCFISDITI
                     RKSRE"
     PFAM_domain     2029..2274
                     /aSDomain="PAS_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08447.14"
                     /description="PAS fold"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg36_146_0001"
                     /evalue="5.50E-12"
                     /label="ctg36_146"
                     /locus_tag="ctg36_146"
                     /protein_end="270"
                     /protein_start="188"
                     /score="45.9"
                     /tool="antismash"
                     /translation="ISESLCALLGYENAQEYLSSACGRSSGFILEEDLQQVRDYVNRKL
                     QSDGTYYCEYRVKCKDGSVCWISDLGKRVSDPDGEEV"
     aSDomain        2362..2730
                     /aSDomain="TIGR00229"
                     /aSTool="tigrfam"
                     /description="sensory_box: PAS domain S-box protein"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg36_146_0002"
                     /evalue="1.30E-09"
                     /identifier="TIGR00229"
                     /label="ctg36_146"
                     /locus_tag="ctg36_146"
                     /protein_end="422"
                     /protein_start="299"
                     /score="36.2"
                     /tool="antismash"
                     /translation="DFLNQLYTSIPCGILQFTTDPEHLTVNINRMVWEFYGYESEEAFN
                     REIRSPIQLILEKDRPGLVEKIDQLRPGEGALNYTRMVQKMDGTSAWINVIMERLTNVE
                     GLDVIQAIFTDVTQVKQCQ"
     PFAM_domain     2392..2715
                     /aSDomain="PAS_9"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13426.9"
                     /description="PAS domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg36_146_0002"
                     /evalue="6.90E-04"
                     /label="ctg36_146"
                     /locus_tag="ctg36_146"
                     /protein_end="417"
                     /protein_start="309"
                     /score="20.0"
                     /tool="antismash"
                     /translation="PCGILQFTTDPEHLTVNINRMVWEFYGYESEEAFNREIRSPIQLI
                     LEKDRPGLVEKIDQLRPGEGALNYTRMVQKMDGTSAWINVIMERLTNVEGLDVIQAIFT
                     DVTQ"
     PFAM_domain     3205..3405
                     /aSDomain="HisKA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00512.27"
                     /description="His Kinase A (phospho-acceptor) domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg36_146_0003"
                     /evalue="5.30E-13"
                     /label="ctg36_146"
                     /locus_tag="ctg36_146"
                     /protein_end="647"
                     /protein_start="580"
                     /score="48.9"
                     /tool="antismash"
                     /translation="AKSDFLSRMSHDIRTPMNAIIGMSAIGQMKLDDPARVRDCFQKID
                     TSSRFLLSLINDILDMSKIENG"
     PFAM_domain     3544..3894
                     /aSDomain="HATPase_c"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02518.28"
                     /description="Histidine kinase-, DNA gyrase B-, and
                     HSP90-like ATPase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg36_146_0004"
                     /evalue="8.30E-28"
                     /label="ctg36_146"
                     /locus_tag="ctg36_146"
                     /protein_end="810"
                     /protein_start="693"
                     /score="97.2"
                     /tool="antismash"
                     /translation="GDALRIKQILMNLLSNTLKFTPPGGRITVEVKELRRTNGFAYLCF
                     QVKDTGIGMSEDFQQKMFTAFEQESQEKARDKVGSGLGLTIVHNLVQMMNGTIQVQSGK
                     GKGTVFQVTLPLE"
     PFAM_domain     3961..4302
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg36_146_0005"
                     /evalue="6.20E-18"
                     /label="ctg36_146"
                     /locus_tag="ctg36_146"
                     /protein_end="946"
                     /protein_start="832"
                     /score="65.1"
                     /tool="antismash"
                     /translation="VLVVDDDALIGEQVAQMMSDIGAVSKWVDSGEKALEEVAASLRLG
                     RTYDVAMIDWKLPGMDGIETTRRMRDLVGPDTTIIIISAYDWSSIQEEARAVGADYFMS
                     KPLFRSTIYQ"
     PFAM_domain     4390..4740
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg36_146_0006"
                     /evalue="9.00E-22"
                     /label="ctg36_146"
                     /locus_tag="ctg36_146"
                     /protein_end="1092"
                     /protein_start="975"
                     /score="77.5"
                     /tool="antismash"
                     /translation="VLLVEDNDLNLEVAQSLLQMSGLQVDTAENGKKAVERFEDAPVGH
                     YMAILMDVRMPVMDGIEATRVIRSLKRADARTVPILAMTANAFDEDRQLAFAAGMSGYL
                     VKPLDIHVLLDEL"
     CDS             5016..7385
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:diguanylate cyclase (Score: 112.6; E-value:
                     5.3e-34)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg36_147"
                     /transl_table=11
                     /translation="MAKRCSFCKIDELRQNDKRKSCVWTETNTATGQNFKNYDNLVEWN
                     GRMYHIQDSVDVTEYIQLTENAAVDELTGMLSRRTGKEMLGEAIEQARREQAILTVALY
                     DVNELKQVNDKYGHAEGDHLLRYIATVVRENLGPRDMAFRLSGDEFVLAFHDADLADAE
                     KHMQRILKQLKAEQEQSGLFYNMSFSYGLLEVYPGDQYAVSDIISRVDEQMYVQKRNYH
                     IMRAKLALAQSAGQTGEVRDFDYDKEHLYDALSVSTDDYMFVGNMHTGVFRYPPAMVDE
                     FGLPGEVVENAAAFWGKLIHPHDEKGFLESNQEIADGRTDYHNIEYRAKNVKGEWIWLR
                     CRGKMIRDENGEPGLFAGSITNLGKNNQVDHMTGLYNRFEFEGAVKKYMVDRASTKSMG
                     ILVLDMDTFKNINDLYNRSFGDEVLRLTAQKISAMLPANAKIYRMDGDEFGIILLNSDM
                     NTCSSIFSRIQHTFRKQQEHSGCKYYCTISGGYASYPQDADNYQDLLKYANYSLEQSKH
                     LGKNRMTVFSAEILEKKERRLELTQLLRESIERGFAGFSIRYQPQVDSRTKVLYGAEAL
                     ARWHCGKYGDISPAEFIPLLEQSGLIIQMGNWILYHAMAQCREWCKMRADFHMSINLSY
                     LQLLEPDIVSYVQQTLSDFRLRPSNITLELTETHLIKEDEAIHGILDDLRKLGIRIAMD
                     DFGVGYSSLFSLKNTPVDTVKIDRGFVKGVTSDLFNATFIRAITELCHNVGKQVCLEGV
                     ETQEEYDAVKNTGLELIQGFYFGQPITSEMFEKKFL"
     aSDomain        5208..5675
                     /aSDomain="TIGR00254"
                     /aSTool="tigrfam"
                     /description="GGDEF: diguanylate cyclase (GGDEF) domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg36_147_0003"
                     /evalue="6.90E-29"
                     /identifier="TIGR00254"
                     /label="ctg36_147"
                     /locus_tag="ctg36_147"
                     /protein_end="220"
                     /protein_start="64"
                     /score="98.7"
                     /tool="antismash"
                     /translation="ENAAVDELTGMLSRRTGKEMLGEAIEQARREQAILTVALYDVNEL
                     KQVNDKYGHAEGDHLLRYIATVVRENLGPRDMAFRLSGDEFVLAFHDADLADAEKHMQR
                     ILKQLKAEQEQSGLFYNMSFSYGLLEVYPGDQYAVSDIISRVDEQMYVQKRN"
     PFAM_domain     5214..5675
                     /aSDomain="GGDEF"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00990.23"
                     /description="Diguanylate cyclase, GGDEF domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg36_147_0007"
                     /evalue="1.40E-32"
                     /label="ctg36_147"
                     /locus_tag="ctg36_147"
                     /protein_end="220"
                     /protein_start="66"
                     /score="112.8"
                     /tool="antismash"
                     /translation="AAVDELTGMLSRRTGKEMLGEAIEQARREQAILTVALYDVNELKQ
                     VNDKYGHAEGDHLLRYIATVVRENLGPRDMAFRLSGDEFVLAFHDADLADAEKHMQRIL
                     KQLKAEQEQSGLFYNMSFSYGLLEVYPGDQYAVSDIISRVDEQMYVQKRN"
     PFAM_domain     5862..6089
                     /aSDomain="PAS_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08447.14"
                     /description="PAS fold"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg36_147_0008"
                     /evalue="3.60E-12"
                     /label="ctg36_147"
                     /locus_tag="ctg36_147"
                     /protein_end="358"
                     /protein_start="282"
                     /score="46.5"
                     /tool="antismash"
                     /translation="GLPGEVVENAAAFWGKLIHPHDEKGFLESNQEIADGRTDYHNIEY
                     RAKNVKGEWIWLRCRGKMIRDENGEPGLFAG"
     aSDomain        6111..6590
                     /aSDomain="TIGR00254"
                     /aSTool="tigrfam"
                     /description="GGDEF: diguanylate cyclase (GGDEF) domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg36_147_0004"
                     /evalue="2.40E-29"
                     /identifier="TIGR00254"
                     /label="ctg36_147"
                     /locus_tag="ctg36_147"
                     /protein_end="525"
                     /protein_start="365"
                     /score="100.1"
                     /tool="antismash"
                     /translation="NNQVDHMTGLYNRFEFEGAVKKYMVDRASTKSMGILVLDMDTFKN
                     INDLYNRSFGDEVLRLTAQKISAMLPANAKIYRMDGDEFGIILLNSDMNTCSSIFSRIQ
                     HTFRKQQEHSGCKYYCTISGGYASYPQDADNYQDLLKYANYSLEQSKHLGKNRMTV"
     PFAM_domain     6117..6581
                     /aSDomain="GGDEF"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00990.23"
                     /description="Diguanylate cyclase, GGDEF domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg36_147_0009"
                     /evalue="1.00E-32"
                     /label="ctg36_147"
                     /locus_tag="ctg36_147"
                     /protein_end="522"
                     /protein_start="367"
                     /score="113.2"
                     /tool="antismash"
                     /translation="QVDHMTGLYNRFEFEGAVKKYMVDRASTKSMGILVLDMDTFKNIN
                     DLYNRSFGDEVLRLTAQKISAMLPANAKIYRMDGDEFGIILLNSDMNTCSSIFSRIQHT
                     FRKQQEHSGCKYYCTISGGYASYPQDADNYQDLLKYANYSLEQSKHLGKNR"
     PFAM_domain     6645..7349
                     /aSDomain="EAL"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00563.22"
                     /description="EAL domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg36_147_0010"
                     /evalue="2.30E-64"
                     /label="ctg36_147"
                     /locus_tag="ctg36_147"
                     /protein_end="778"
                     /protein_start="543"
                     /score="217.2"
                     /tool="antismash"
                     /translation="LRESIERGFAGFSIRYQPQVDSRTKVLYGAEALARWHCGKYGDIS
                     PAEFIPLLEQSGLIIQMGNWILYHAMAQCREWCKMRADFHMSINLSYLQLLEPDIVSYV
                     QQTLSDFRLRPSNITLELTETHLIKEDEAIHGILDDLRKLGIRIAMDDFGVGYSSLFSL
                     KNTPVDTVKIDRGFVKGVTSDLFNATFIRAITELCHNVGKQVCLEGVETQEEYDAVKNT
                     GLELIQGFYFGQP"
     CDS             7781..8911
                     /locus_tag="ctg36_148"
                     /transl_table=11
                     /translation="MFTLKKQELRARRAQFETVHGTIQTPAFMNVGTSATIKGGISSID
                     LVELKCQVELCNTYHLHIRPGDDVIRQLGGLHKFMNWQRPILTDSGGFQVFSLASLRKI
                     KEEGVYFASHIDGKRIFMGPEESMRIQSNLGSTIAMAFDECVENPATLAYATKSCDRTT
                     RWLYRCKEEMERLNSLPDTINPKQLLFGINQGCTFENLRIKHMQEIAQLDLDGYAIGGL
                     AVGEPTGEMYRIIEEVEPYMPKEKPRYLMGVGTPVNIIEAVWRGIDLFDCVMPSRNARH
                     GHLFTWKGRINIHNAKYQLDDTPIDDSCDCPACKHHSKAYIRHLFKAGEMLGMRLCVQH
                     NLHFYNTLMERVREALDEGRFAEFREKYKNILDKRI"
     aSDomain        7784..8893
                     /aSDomain="TIGR00449"
                     /aSTool="tigrfam"
                     /description="tgt_general: tRNA-guanine family
                     transglycosylase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg36_148_0006"
                     /evalue="1.50E-142"
                     /identifier="TIGR00449"
                     /label="ctg36_148"
                     /locus_tag="ctg36_148"
                     /protein_end="371"
                     /protein_start="1"
                     /score="472.8"
                     /tool="antismash"
                     /translation="FTLKKQELRARRAQFETVHGTIQTPAFMNVGTSATIKGGISSIDL
                     VELKCQVELCNTYHLHIRPGDDVIRQLGGLHKFMNWQRPILTDSGGFQVFSLASLRKIK
                     EEGVYFASHIDGKRIFMGPEESMRIQSNLGSTIAMAFDECVENPATLAYATKSCDRTTR
                     WLYRCKEEMERLNSLPDTINPKQLLFGINQGCTFENLRIKHMQEIAQLDLDGYAIGGLA
                     VGEPTGEMYRIIEEVEPYMPKEKPRYLMGVGTPVNIIEAVWRGIDLFDCVMPSRNARHG
                     HLFTWKGRINIHNAKYQLDDTPIDDSCDCPACKHHSKAYIRHLFKAGEMLGMRLCVQHN
                     LHFYNTLMERVREALDEGRFAEFREKYKNI"
     aSDomain        7784..8899
                     /aSDomain="TIGR00430"
                     /aSTool="tigrfam"
                     /description="Q_tRNA_tgt: tRNA-guanine transglycosylase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg36_148_0005"
                     /evalue="1.00E-148"
                     /identifier="TIGR00430"
                     /label="ctg36_148"
                     /locus_tag="ctg36_148"
                     /protein_end="373"
                     /protein_start="1"
                     /score="493.2"
                     /tool="antismash"
                     /translation="FTLKKQELRARRAQFETVHGTIQTPAFMNVGTSATIKGGISSIDL
                     VELKCQVELCNTYHLHIRPGDDVIRQLGGLHKFMNWQRPILTDSGGFQVFSLASLRKIK
                     EEGVYFASHIDGKRIFMGPEESMRIQSNLGSTIAMAFDECVENPATLAYATKSCDRTTR
                     WLYRCKEEMERLNSLPDTINPKQLLFGINQGCTFENLRIKHMQEIAQLDLDGYAIGGLA
                     VGEPTGEMYRIIEEVEPYMPKEKPRYLMGVGTPVNIIEAVWRGIDLFDCVMPSRNARHG
                     HLFTWKGRINIHNAKYQLDDTPIDDSCDCPACKHHSKAYIRHLFKAGEMLGMRLCVQHN
                     LHFYNTLMERVREALDEGRFAEFREKYKNILD"
     PFAM_domain     7811..8887
                     /aSDomain="TGT"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01702.20"
                     /description="Queuine tRNA-ribosyltransferase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg36_148_0011"
                     /evalue="5.00E-146"
                     /label="ctg36_148"
                     /locus_tag="ctg36_148"
                     /protein_end="369"
                     /protein_start="10"
                     /score="486.5"
                     /tool="antismash"
                     /translation="ARRAQFETVHGTIQTPAFMNVGTSATIKGGISSIDLVELKCQVEL
                     CNTYHLHIRPGDDVIRQLGGLHKFMNWQRPILTDSGGFQVFSLASLRKIKEEGVYFASH
                     IDGKRIFMGPEESMRIQSNLGSTIAMAFDECVENPATLAYATKSCDRTTRWLYRCKEEM
                     ERLNSLPDTINPKQLLFGINQGCTFENLRIKHMQEIAQLDLDGYAIGGLAVGEPTGEMY
                     RIIEEVEPYMPKEKPRYLMGVGTPVNIIEAVWRGIDLFDCVMPSRNARHGHLFTWKGRI
                     NIHNAKYQLDDTPIDDSCDCPACKHHSKAYIRHLFKAGEMLGMRLCVQHNLHFYNTLME
                     RVREALDEGRFAEFREKYK"
     CDS             9058..9423
                     /locus_tag="ctg36_149"
                     /transl_table=11
                     /translation="MDKFLLDAAASGADAAAGNSTMAVVIQWGFLILVIVGLYFLFIRP
                     QKKREKEAQDMRSNIEIGDEIVTAGGLIGRVVSVRDDTLVIETGTDRNKVRIARWAIQA
                     NNSLAEEKDIKDTKEVK"
     PFAM_domain     9145..9366
                     /aSDomain="YajC"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02699.17"
                     /description="Preprotein translocase subunit"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg36_149_0012"
                     /evalue="6.80E-26"
                     /label="ctg36_149"
                     /locus_tag="ctg36_149"
                     /protein_end="103"
                     /protein_start="29"
                     /score="90.1"
                     /tool="antismash"
                     /translation="FLILVIVGLYFLFIRPQKKREKEAQDMRSNIEIGDEIVTAGGLIG
                     RVVSVRDDTLVIETGTDRNKVRIARWAIQ"
     aSDomain        9145..9369
                     /aSDomain="TIGR00739"
                     /aSTool="tigrfam"
                     /description="yajC: preprotein translocase, YajC subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg36_149_0007"
                     /evalue="3.30E-22"
                     /identifier="TIGR00739"
                     /label="ctg36_149"
                     /locus_tag="ctg36_149"
                     /protein_end="104"
                     /protein_start="29"
                     /score="76.3"
                     /tool="antismash"
                     /translation="FLILVIVGLYFLFIRPQKKREKEAQDMRSNIEIGDEIVTAGGLIG
                     RVVSVRDDTLVIETGTDRNKVRIARWAIQA"
     CDS             9559..9984
                     /locus_tag="ctg36_150"
                     /transl_table=11
                     /translation="VIIVREKTKSTKASRQRHLYIKATCVGVGSGLLIYLIILLTFSII
                     FTLQDMPEMATLPVGIVALVAGSYLAGYITCKMTHRKGAVLGALCGGILFLMVFITNLI
                     VNHSQPFSGLFFTKLLIVLLSAIIGGVVGANSKKRRV"
     PFAM_domain     9619..9957
                     /aSDomain="DUF3792"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12670.9"
                     /description="Protein of unknown function (DUF3792)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg36_150_0013"
                     /evalue="7.90E-15"
                     /label="ctg36_150"
                     /locus_tag="ctg36_150"
                     /protein_end="133"
                     /protein_start="20"
                     /score="55.1"
                     /tool="antismash"
                     /translation="IKATCVGVGSGLLIYLIILLTFSIIFTLQDMPEMATLPVGIVALV
                     AGSYLAGYITCKMTHRKGAVLGALCGGILFLMVFITNLIVNHSQPFSGLFFTKLLIVLL
                     SAIIGGVVG"
     aSDomain        9625..9963
                     /aSDomain="TIGR04086"
                     /aSTool="tigrfam"
                     /description="TIGR04086_membr: putative membrane protein,
                     TIGR04086 family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg36_150_0008"
                     /evalue="3.40E-17"
                     /identifier="TIGR04086"
                     /label="ctg36_150"
                     /locus_tag="ctg36_150"
                     /protein_end="135"
                     /protein_start="22"
                     /score="60.6"
                     /tool="antismash"
                     /translation="ATCVGVGSGLLIYLIILLTFSIIFTLQDMPEMATLPVGIVALVAG
                     SYLAGYITCKMTHRKGAVLGALCGGILFLMVFITNLIVNHSQPFSGLFFTKLLIVLLSA
                     IIGGVVGAN"
     CDS             10001..10141
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR03973"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SCIFF"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg36_151"
                     /sec_met_domain="TIGR03973 (E-value: 6.4e-26, bitscore:
                     83.3, seeds: 29, tool: rule-based-clusters)"
                     /sec_met_domain="SCIFF (E-value: 3.6e-26, bitscore: 84.2,
                     seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHVKTINNANLKESAVKGGCGECQASCQSACKTSCTVANQKCEN
                     K"
     aSDomain        10004..10132
                     /aSDomain="TIGR03973"
                     /aSTool="tigrfam"
                     /description="six_Cys_in_45: six-cysteine peptide SCIFF"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg36_151_0009"
                     /evalue="1.90E-24"
                     /identifier="TIGR03973"
                     /label="ctg36_151"
                     /locus_tag="ctg36_151"
                     /protein_end="44"
                     /protein_start="1"
                     /score="83.3"
                     /tool="antismash"
                     /translation="KHVKTINNANLKESAVKGGCGECQASCQSACKTSCTVANQKCE"
     PFAM_domain     10004..10135
                     /aSDomain="SCIFF"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13165.8"
                     /description="Six-cysteine peptide SCIFF"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg36_151_0014"
                     /evalue="4.10E-24"
                     /label="ctg36_151"
                     /locus_tag="ctg36_151"
                     /protein_end="45"
                     /protein_start="1"
                     /score="84.3"
                     /tool="antismash"
                     /translation="KHVKTINNANLKESAVKGGCGECQASCQSACKTSCTVANQKCEN"
     CDS             10250..11611
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SPASM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg36_152"
                     /sec_met_domain="PF04055 (E-value: 1.1e-12, bitscore: 41.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 4.8e-15, bitscore: 49.4,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 1.4e-21, bitscore:
                     70.0, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 4.1e-08, bitscore: 27.0,
                     seeds: 166, tool: rule-based-clusters)"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 9.3e-25,
                     bitscore: 80.1, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHKYFLNGYYIVLDVNSGAIHVVDELIYNMLDLVEPPVLPKCPQ
                     SVLNAFKGRYNLDEIYEAYDEIYGLYDIGQLYSEDDYEQFAGMMVNSPIKAMCLHIAHD
                     CNLRCEYCFASTGDFGEGRRLMTYETGKKAIDFLIEHSQGRRNLEMDFFGGEPLMNFGV
                     VKQLVEYARSLEEKHHKKFRFTITTNGMLLTDDKIDFINKEMSNVVLSIDGRKEVTDRV
                     RSRVDGSGCYDVIMPKFQKLVEKRGPKDYYVRGTFTKYNLDFTKDVLHLYDAGFDQISV
                     EPVVSDPALPYSITENDLPVIFDEYETLAQTILACRKAGRYFNFFHFMLDLDQGPCAIK
                     RLRGCGCGNEYVAITPDGDIYPCHQFVGQEEWKMGNLEDGSFDKERKADFATANVYTKP
                     ECKECWAKFYCSGGCNANNQNYEGDIRHAHKLSCDLEKKRLECAIMIKAAEAQG"
     aSDomain        10253..11596
                     /aSDomain="TIGR03974"
                     /aSTool="tigrfam"
                     /description="rSAM_six_Cys: SCIFF radical SAM maturase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg36_152_0010"
                     /evalue="2.30E-217"
                     /identifier="TIGR03974"
                     /label="ctg36_152"
                     /locus_tag="ctg36_152"
                     /protein_end="449"
                     /protein_start="1"
                     /score="720.2"
                     /tool="antismash"
                     /translation="IHKYFLNGYYIVLDVNSGAIHVVDELIYNMLDLVEPPVLPKCPQS
                     VLNAFKGRYNLDEIYEAYDEIYGLYDIGQLYSEDDYEQFAGMMVNSPIKAMCLHIAHDC
                     NLRCEYCFASTGDFGEGRRLMTYETGKKAIDFLIEHSQGRRNLEMDFFGGEPLMNFGVV
                     KQLVEYARSLEEKHHKKFRFTITTNGMLLTDDKIDFINKEMSNVVLSIDGRKEVTDRVR
                     SRVDGSGCYDVIMPKFQKLVEKRGPKDYYVRGTFTKYNLDFTKDVLHLYDAGFDQISVE
                     PVVSDPALPYSITENDLPVIFDEYETLAQTILACRKAGRYFNFFHFMLDLDQGPCAIKR
                     LRGCGCGNEYVAITPDGDIYPCHQFVGQEEWKMGNLEDGSFDKERKADFATANVYTKPE
                     CKECWAKFYCSGGCNANNQNYEGDIRHAHKLSCDLEKKRLECAIMIKAA"
     PFAM_domain     10541..10906
                     /aSDomain="Fer4_12"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13353.8"
                     /description="4Fe-4S single cluster domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg36_152_0015"
                     /evalue="1.70E-13"
                     /label="ctg36_152"
                     /locus_tag="ctg36_152"
                     /protein_end="219"
                     /protein_start="97"
                     /score="51.3"
                     /tool="antismash"
                     /translation="CLHIAHDCNLRCEYCFASTGDFGEGRRLMTYETGKKAIDFLIEHS
                     QGRRNLEMDFFGGEPLMNFGVVKQLVEYARSLEEKHHKKFRFTITTNGMLLTDDKIDFI
                     NKEMSNVVLSIDGRKEVT"
     PFAM_domain     11282..11464
                     /aSDomain="SPASM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13186.8"
                     /description="Iron-sulfur cluster-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg36_152_0016"
                     /evalue="5.20E-06"
                     /label="ctg36_152"
                     /locus_tag="ctg36_152"
                     /protein_end="405"
                     /protein_start="344"
                     /score="26.9"
                     /tool="antismash"
                     /translation="CGCGNEYVAITPDGDIYPCHQFVGQEEWKMGNLEDGSFDKERKAD
                     FATANVYTKPECKECW"
     aSDomain        11282..11548
                     /aSDomain="TIGR04085"
                     /aSTool="tigrfam"
                     /description="rSAM_more_4Fe4S: radical SAM additional
                     4Fe4S-binding SPASM domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg36_152_0011"
                     /evalue="4.20E-20"
                     /identifier="TIGR04085"
                     /label="ctg36_152"
                     /locus_tag="ctg36_152"
                     /protein_end="433"
                     /protein_start="344"
                     /score="70.0"
                     /tool="antismash"
                     /translation="CGCGNEYVAITPDGDIYPCHQFVGQEEWKMGNLEDGSFDKERKAD
                     FATANVYTKPECKECWAKFYCSGGCNANNQNYEGDIRHAHKLSC"
     CDS             11608..12780
                     /locus_tag="ctg36_153"
                     /transl_table=11
                     /translation="MNRHEFASLLDRVIKERMLKKITLSKSALPGVARIQIRPFEKGGS
                     AMVQLSKFQEDNKVIHENLPADGAGEEIISLFMDFFKQCNIVTAAGNCEAKCNKKGSLY
                     VKNQIDFSRQETAAASSHDKQKRHFLPPNQPVAFLQELGISGTDGRVYDRMAHKLAQIN
                     RFLELIDDVKDSLPENRPVRIFDLCCGKSYLTFAVHHYFTQILHRQVEMVGVDLKEDVI
                     EHCSRTAEKLGLAGLTFQCGDILQFEPDSKPDMVLSLHACDTATDIVLNTAVRLGTGII
                     LSSPCCHHELAQQLQSEELHLITDYGILQQKLCEISTDALRAQALKISGYQVQLIEFID
                     PENTPKNLLIRAVKNRGKMDEAKKNKLVNEYQCLCEMLNVNPTLKRLLNI"
     PFAM_domain     12076..12489
                     /aSDomain="Methyltransf_32"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13679.8"
                     /description="Methyltransferase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg36_153_0017"
                     /evalue="5.10E-29"
                     /label="ctg36_153"
                     /locus_tag="ctg36_153"
                     /protein_end="294"
                     /protein_start="156"
                     /score="101.4"
                     /tool="antismash"
                     /translation="HKLAQINRFLELIDDVKDSLPENRPVRIFDLCCGKSYLTFAVHHY
                     FTQILHRQVEMVGVDLKEDVIEHCSRTAEKLGLAGLTFQCGDILQFEPDSKPDMVLSLH
                     ACDTATDIVLNTAVRLGTGIILSSPCCHHELAQQ"
     CDS             12819..12929
                     /locus_tag="ctg36_154"
                     /transl_table=11
                     /translation="MAVLWMVCAIFLWSTALLVIGNVVANLANIRHRMKQ"
ORIGIN
        1 cgacgaaaag cgcgcctcgc aggcgctgca gttccaggcg gagcgggacg agctgaccca
       61 gctttacaac aagcgcgccg cccgcaggat gattgagagc agtctggaca cacggctgcc
      121 ggaggaagcc ttcgcgctat tgatcatcga cgtggacaac ttcaagcaga tcaacgacag
      181 cttcggccac atgttcggcg acgttgtgct gcgggagatc tccgcggtcc tgcagaacct
      241 gttccgcagc gtcgatatca tctccagaat cggcggcgat gagtttctgg tgttcatgcg
      301 gaatatagcc gacattgagg tcgtaaagga acgtgcctcc caggtaatcg aggcgctgcg
      361 caacctgttc accgacaacg tgatcgagtg cgttccatcc tgcagcatcg gcgtttcctt
      421 ctgcccgcag gacggcgccc attttgatgt tctcttccag cacagcgatc ttgcgctgta
      481 taaggcgaag gccatgggca agaaccgcta cacgctgtat gataaatcga tggacagcct
      541 gttcagtctc ccccatcagc aggcggccaa cacacggatt gatccgcaca gctttgccgg
      601 catcgtcgac aacagtctgg tggagcaggt gttccagaag ctgtatgaat ccgttgacct
      661 ggatcaggcg atcgactcca tcctggagat gatcggcagg cagttcgagg tcagccgcgt
      721 ttatatcttt gaggattccg aagacggggc atcctactgc aacacctacg agtggtgcaa
      781 tgaaggcatc cagccgcaga aacagatgct gctgcacggc agctatgccg atttgggcgg
      841 gcgcggcagc tatcagtcgc tcttcggcga gcagggtatc ttctactgca ccgacatcgg
      901 gcagcttccc gccgcagtca aagagctgct gggcatgcag gggatcaagt cgatcctgca
      961 gtgcgcgatc cgggatgcac agggctggta tggtttcatc ggcttcgacg actgtgtgat
     1021 cacacggtac tggaccaagg aacagatcaa cgcgctggcc tttacctcca agctgctctc
     1081 gatctttctg ctgaaaaaac gggcgcagga gcaggctctc aaaaaggccg aagacctgcg
     1141 gatggtactg gaccatcaga acgcatggat ctatgtcgtg gacgcaaaca cccatcagct
     1201 gcgctacatc aatgcgaaga cccatgtcat cgcgccgaac gccagagagg gaatgcgctg
     1261 ctacaacgca ttttttggcc gttcctcgcc gtgcaaaacc tgtcccatga agatcaaaca
     1321 gcctattgaa atacacaatc cccgtctgaa cgtttgggta atggtcgacg cggtgccgat
     1381 gcgctgggag gatgaggatt cctatctgct gacctgctac gatatcacag cgtacaagaa
     1441 gaatttaggt gaggagcaga agccatgatg actgaagaga tccgaaacga agtggaagca
     1501 ttcgccagaa aaatcctgta ccgttatttc tgcgagtcgg atgtcgactt cttaatctcc
     1561 accttcgcgc ccgacatcgt ctggctgggt gccgggaaag aacagaaggc cgagggaaag
     1621 gacgccgttg cggcgcagtt cctggccggc agatccgacc tcgcgccctg tgacatgtcc
     1681 ggagaacggt atgtatcccg cgagcttgcg gacggcgtct acctctgtga aggcgacagc
     1741 tggctgcagc ccaagcccga aaccggcctg tatttcagga cccaccagcg cgtcaccttc
     1801 atctttaagc gcacagagga cggatttcaa tgtctgcaca tccacaattc ggtggattat
     1861 tcggacatcc aggacggtga gcttttcccc gctcaggccg cgcaggaagc ctacaggcgg
     1921 atgcaggaga ctttgaacaa gcagaaccgc cagattgaac tgatgctttc ccagctgccg
     1981 ggcggcatgc tgatctgcca ggcggacgaa gattttaccg tcaaatggat cagcgaatcc
     2041 ctgtgcgccc tgctgggcta cgaaaacgcg caggagtact tatcctccgc ctgtggcagg
     2101 agcagcggct ttatcctgga ggaggacctg cagcaggtgc gggactatgt gaacagaaag
     2161 ctgcagtccg acggcaccta ttactgtgaa taccgcgtca aatgcaagga cggcagcgtc
     2221 tgctggattt cggacctcgg caagcgggta tcggacccgg atggagaaga ggtgatctac
     2281 tgcttcatct cggacatcac gatccgcaaa agcagggagc tgcagattgc caaggcaaat
     2341 gaagaggttc ggcggcaggc tgactttttg aaccagcttt acacctcgat tccctgcggc
     2401 atcctgcagt tcacgaccga tccggagcat ttgaccgtca atataaaccg catggtgtgg
     2461 gaattctacg gttatgaatc ggaagaagca ttcaacaggg aaatccgctc cccgattcag
     2521 ctgattctcg aaaaggaccg gccgggactg gtggagaaga tcgaccagct gcgcccgggc
     2581 gaaggagcgc tcaactacac gcgcatggtg cagaaaatgg acggcaccag cgcctggatc
     2641 aacgtcatca tggaacgcct gaccaacgtg gagggtttgg acgtcatcca ggccatcttc
     2701 accgacgtca cgcaggtcaa gcagtgccag ctggagcagg agcgcgaacg gctgatcgaa
     2761 aaccggtcgc tgcgcgccgc aacctgcacg gcctatccgc tgattatgag cgtcaacctg
     2821 acacaggaca cctacaactg ctttattgaa gaacagaact gccctctgga acaccggcag
     2881 ggcagctttg atgaaatggt cgcaagatcc attccggata tctatccctc ctaccgtgag
     2941 gattttgcaa aaacctttga ccgaaaggaa atcctgcggc ggtttgcagc gggagaacgc
     3001 gagatctaca tggagcttca gcagatgggc gcggatggaa aataccactg gatatcggtc
     3061 catctgatct atgtcgacaa tccgataggc ggagacgtgt tggctatcga tcttgtcaag
     3121 gtgctcgatc accagcgtca ggagcaggcg cggcaggaac agctgctgcg cgacgcgctg
     3181 tccgccgcgc gggctgccaa caatgccaag tccgacttcc tctcgcggat gtcccatgat
     3241 atccgcaccc cgatgaacgc catcatcggc atgagcgcga tcgggcagat gaagctggat
     3301 gatcccgccc gcgtcagaga ctgcttccag aaaatagaca catcctcccg gttcctgctg
     3361 tcgctgatca acgatattct ggacatgtcc aaaatagaaa acggaaagat gagtctgaca
     3421 cacgaacagt tcgattttac cgagctgttc gacgagatca tctccatcat ctatccgcag
     3481 acattggatt taaggcttac ttttgaggta catcatcagg agccgattga gaaatactat
     3541 atcggtgatg ctctgcgcat caagcagatt ctgatgaacc tgctctccaa cacgctgaaa
     3601 ttcacgccgc ccggcggccg tatcacggtg gaagtcaaag aactgcgccg caccaacggc
     3661 tttgcctatc tgtgttttca ggtcaaggac accggcatcg gcatgtcaga ggacttccag
     3721 cagaagatgt tcaccgcatt tgagcaggaa tcgcaggaaa aagcccgcga caaggtggga
     3781 agcgggcttg gccttacgat cgttcacaac ctggtccaga tgatgaacgg caccattcag
     3841 gtgcagagcg ggaagggcaa gggcaccgtt tttcaggtca cccttcctct ggagcttgcc
     3901 gaggacaacg aagcggcgga acggcagcgc aaatccaagg agcttctgcg ggacatgcag
     3961 gtattggtgg tggacgacga cgcgctcatc ggcgagcagg tcgcccagat gatgagcgac
     4021 atcggcgccg tctccaaatg ggtggattcc ggcgagaagg cgctcgagga ggttgcggcc
     4081 agcctcaggc tcggacggac gtacgacgtc gccatgatcg actggaagct gcccggcatg
     4141 gacggcatcg agacgacccg cagaatgcgg gacctggtag gcccggatac gacgatcatc
     4201 atcatttcgg cgtatgactg gagcagcatc caggaggaag caagagcggt cggcgccgac
     4261 tatttcatgt caaagccgct gttccgctcc accatttatc agaccttcaa tcaactgggg
     4321 catgattcgc cgctcagtgg gaaaacctcc gcgcccgcac atgtcggcga ctgtttctcc
     4381 aatcagcgtg tcctgctggt ggaggacaac gacctgaatc tggaagttgc gcagtctctg
     4441 cttcagatgt ccggcctgca ggtcgatacg gcggaaaacg gaaaaaaagc tgttgaacgg
     4501 ttcgaagacg cacccgtcgg gcattatatg gcaattctga tggacgtgcg catgccggtc
     4561 atggacggta tcgaagcgac ccgtgtcatc cgcagcctga agcgcgcgga tgcccggacg
     4621 gtccccattc tggccatgac cgccaacgcc ttcgatgagg accggcagct cgcattcgcg
     4681 gccggcatgt ccggttacct tgttaaaccg ctggacatcc atgtcctgct ggacgagctg
     4741 aaaaagctgc aataaatcta cgaagcccga atgggccttt tcacacaatt gggctgatgt
     4801 tatatgtcag gggaaagagg tgcttttatg gctgccgatc aggaatcctt tttggacggc
     4861 acatttttca aatcggtgct ggacagcatg aacacaaacg tttacatcac cgatgtagaa
     4921 accgatgaaa tcgtctatat gaacgacgcg atgaaaaaac cttccatctg gagcatccgg
     4981 aaggctgtat ctgctggaag gtcctgcaga agggtatggc aaaacggtgc agtttctgca
     5041 aaattgacga actccggcag aatgacaaac ggaaaagctg tgtgtggaca gaaaccaaca
     5101 ccgcaacagg acagaatttt aaaaattatg acaatctcgt cgaatggaac ggacggatgt
     5161 atcacattca ggattccgtc gacgtcaccg aatatatcca gctcaccgaa aacgccgccg
     5221 tggatgagct gaccggcatg ctcagccgcc gtacaggaaa agaaatgctg ggcgaagcca
     5281 tcgagcaggc caggcgggaa caggccattt tgaccgtcgc attgtacgac gtcaacgaac
     5341 tcaaacaggt caacgacaag tacggccatg ccgagggaga ccatctgctg cggtatatcg
     5401 ccacggtcgt cagggagaac ctggggccgc gcgatatggc gttccgcctg agcggggacg
     5461 aattcgtgct ggcattccat gacgccgatc tggcggacgc ggagaaacac atgcagcgga
     5521 ttttaaaaca gctgaaagcc gaacaggagc agtccggcct tttctacaac atgtccttca
     5581 gctacgggct tttggaggtc tatccgggcg accagtacgc ggtttccgac atcatctcgc
     5641 gggttgacga gcagatgtac gttcagaaac gcaactacca catcatgcgc gccaagctgg
     5701 ccttggccca gtcggccggt cagacgggtg aagtccggga tttcgactac gacaaggagc
     5761 atctgtacga tgcgctgtcg gtcagtacgg acgactatat gttcgttggg aacatgcaca
     5821 ccggcgtgtt ccgctatccg cccgctatgg tggacgaatt cggcctgcct ggggaggttg
     5881 tggaaaacgc ggccgccttt tggggaaagc tgatccatcc gcacgacgaa aaagggtttc
     5941 tcgaaagcaa tcaggagatt gccgacggac gcaccgatta ccacaacatc gaataccggg
     6001 cgaaaaacgt caagggcgaa tggatctggc tgcgctgccg tggtaagatg atccgtgacg
     6061 agaacgggga accgggactg tttgccggca gcatcaccaa cctcggcaag aacaatcagg
     6121 tcgaccatat gaccggctta tacaacaggt tcgaattcga aggggcggtc aagaaataca
     6181 tggttgaccg cgcctccacc aaaagcatgg gcattctggt tttggatatg gacaccttca
     6241 aaaacatcaa cgacctgtac aaccggtcat tcggcgacga ggtgctgcgc ctgaccgccc
     6301 agaagatttc ggcaatgctg ccggccaacg caaagatcta ccggatggac ggcgatgagt
     6361 tcggcatcat cctgctgaac agcgatatga acacctgttc cagcatcttc agccgcatcc
     6421 agcacacctt ccgcaagcag caggagcaca gcggctgcaa gtactactgc accatttcgg
     6481 gcggctacgc atcctatccg caggacgccg acaactacca ggaccttttg aaatacgcga
     6541 actattccct ggaacagtcc aaacatttgg gcaaaaaccg gatgaccgtc ttttccgcag
     6601 agattctgga aaagaaggag aggcgtctgg aattgacgca gctgttgcgt gaaagcatcg
     6661 aacggggatt tgcgggcttt tccatccgat atcagccgca ggtggattcc aggactaagg
     6721 tgctctatgg agccgaggct ctcgcccgct ggcactgcgg caaatacggg gacatctccc
     6781 ccgcggaatt catcccgctg ctcgaacaga gcggcctgat tatccagatg gggaactgga
     6841 tcctctacca cgcgatggcg cagtgccggg agtggtgcaa aatgcgcgcc gatttccaca
     6901 tgagcatcaa cctgtcatac ctgcagctgc tcgaaccgga catcgtcagc tatgtgcagc
     6961 agaccctcag cgatttcagg ctgcggccct ccaacatcac gctggagctc accgaaaccc
     7021 acctgatcaa ggaagatgag gcgatccacg gcatcttgga cgatctgaga aagctgggca
     7081 tccgcatcgc gatggacgat ttcggcgtgg gctattcctc gctgttctcc ctgaaaaata
     7141 cgccggtaga cactgtcaag atcgaccgcg gctttgtgaa gggcgtcacc tccgacctgt
     7201 tcaacgcgac ctttatccgg gctatcacag aactgtgcca caacgtcggc aagcaggtct
     7261 gcctggaggg cgtcgagacg caggaggaat acgacgcggt caaaaacacc ggcctggagc
     7321 tgattcaggg cttttacttc ggccagccca tcacatcgga gatgtttgag aagaagttcc
     7381 tgtgaccacc acttcccgca ggcagataat atggctgtgt ccgttgtctg atatggaata
     7441 cagccaggta tcaggcagtc gtacggaagt tattccatcc agaccgaaaa acatacgaac
     7501 aaaccgcctt tacagacatg cggatacgat ggttcttcaa ccgcgcgcag tatgccacgg
     7561 caaaatcaac cgccttaaca ggcaagcaga tatgatgacc cttcaacttg cgcgcagtat
     7621 gccactgcaa aatcaatcgc cttagcaggc gggcggatac gataacagcc ttttcgttct
     7681 cccctgcaat gacgacgcgg ccatccttca aagccaggct gtcccgatgc gggcataccg
     7741 catcatcttc ccatctcaaa actatggagt gtttctatct atgtttacat taaaaaagca
     7801 ggagctgcgc gccaggcgcg cccagtttga aacggttcac ggaaccatac agaccccagc
     7861 gttcatgaat gtcggcacca gcgccaccat caagggaggt atctcctcca tcgacctggt
     7921 cgagctgaaa tgccaggttg agctttgcaa cacctatcac ctgcatatcc gtccgggcga
     7981 cgatgtgatc cgtcagcttg gcggcctgca caagttcatg aactggcagc ggccgatcct
     8041 gaccgattcc ggcggcttcc aggtgttttc actggcgtcg cttcgcaaga tcaaagagga
     8101 gggcgtctac ttcgcctccc atatcgacgg caagcgcatc tttatgggac cggaggaaag
     8161 catgcgcatc cagtcgaatc tgggttccac gatcgcgatg gcgttcgacg agtgcgtcga
     8221 aaaccccgcg acgctcgcct acgcgaccaa gagctgcgac cgaaccaccc gctggcttta
     8281 ccgctgcaag gaagagatgg aacggctcaa ttctctgcct gataccatca accccaaaca
     8341 gctgctgttc ggcatcaatc agggctgtac ctttgagaac ctgcgcatca agcatatgca
     8401 ggagattgcg cagcttgact tggacggcta cgcaatcggc ggactggccg tgggcgaacc
     8461 gaccggcgag atgtaccgca tcatcgaaga ggtggagcca tatatgccaa aggagaagcc
     8521 ccgctatctg atgggggtcg gcacgccagt caacatcatc gaagcggtgt ggcgcggcat
     8581 cgacctgttc gactgcgtga tgcccagccg caatgcgcgc cacgggcacc tgttcacctg
     8641 gaagggccgc atcaacatcc acaacgcgaa gtatcagctg gacgacacgc caatcgatga
     8701 cagctgcgac tgcccggcct gcaaacatca ctccaaggcg tacatccgtc atctgttcaa
     8761 agcgggcgag atgctcggca tgcggctgtg cgtccagcac aacctccatt tctacaatac
     8821 gctgatggaa cgcgtccggg aagcgctgga tgagggccgg tttgcagaat tccgggaaaa
     8881 atataagaat attttagaca aacggatata aactgacaaa aacagcttgc atcccgccaa
     8941 aaatccatgt ataataagat ttgtatcgtt tacggcgcgg cagtttccgt gccaggaatt
     9001 tgatcatgat gaagacgtta caaaaggata gaaatcgtac atggaggtgc aaacacaatg
     9061 gacaagtttt tattggatgc ggctgcttcc ggcgcggatg ctgctgccgg caacagcaca
     9121 atggctgtgg ttattcagtg gggctttttg atcctggtta ttgtcggtct ttatttcctg
     9181 ttcatccgcc cgcagaaaaa gcgtgagaag gaagcgcagg atatgcgcag caacatcgag
     9241 atcggcgacg agatcgtcac agccggcggc ctgatcggac gggttgtctc ggtacgggac
     9301 gacacgctgg tcatcgaaac tggaaccgac cgcaacaagg tccgcattgc ccgttgggcg
     9361 attcaggcca acaactcctt agccgaggaa aaggatatca aggataccaa agaagttaaa
     9421 tagaccaaaa attttacacc gggtattttt tgagactgtc ttaccgattt gttaagaaac
     9481 tttcattttt tgtcatattc atgcaatctc accaatatct ttttattata aaatacaggc
     9541 gtatttcaag gataaaaggt gataattgtg cgagaaaaga caaaatcgac caaagccagt
     9601 cggcaaaggc atctctacat aaaagcaacc tgcgtgggtg ttggctccgg cctgctcatc
     9661 tatttgatca tcctgctgac gttctctatc atctttacgc tgcaggatat gcctgaaatg
     9721 gccacactgc cggtcggcat cgtggcgctg gtggcgggca gctatctcgc cggttacatc
     9781 acctgcaaaa tgacccatcg aaaaggcgcg gtgctgggcg cgttgtgcgg cggcatcctg
     9841 ttcctgatgg ttttcatcac aaacctgatt gtaaaccaca gccaaccctt ttcggggctg
     9901 ttctttacca agcttttgat cgtcctgctc tcggccatca tcggcggagt ggtgggcgcc
     9961 aattctaaaa aaagaagagt gtaagggagg taatgttatt atgaaacatg tcaaaacaat
    10021 caacaacgca aacttaaaag aatccgctgt caagggcggc tgcggcgagt gccaggcttc
    10081 ctgccagtcg gcctgcaaaa catcctgcac cgttgccaat cagaaatgcg aaaacaaata
    10141 agcattgttt ttgcctgcaa tattggatca acatctcaaa gggcggacac gtaaaggttc
    10201 cgcccttttt gtatgctggg aaccttgctt tgaatgggag ttatagagaa tgatacataa
    10261 gtacttttta aacggctatt acatcgtgct ggatgtgaac agcggcgcca tccatgtggt
    10321 ggatgaactg atctacaaca tgctggacct ggtggaaccc ccggtcctgc caaaatgtcc
    10381 gcagagcgtc ctcaacgcgt tcaagggccg ttataatttg gatgaaatct acgaagcgta
    10441 tgatgagatt tacggcctgt atgacatcgg acagctttac agcgaggacg actacgagca
    10501 gttcgccggt atgatggtga actccccgat caaggcgatg tgcctgcaca tcgcgcacga
    10561 ctgcaacctg agatgtgaat actgcttcgc ctccaccggc gatttcggcg agggccgcag
    10621 gcttatgacc tatgaaaccg gcaaaaaggc gattgacttc ttgattgagc attcgcaggg
    10681 acgccgcaat ctggagatgg acttcttcgg cggcgaaccg ctgatgaatt tcggcgtggt
    10741 caagcagctc gtcgagtatg ccagaagtct cgaagagaag catcacaaga agttccgctt
    10801 caccatcacc accaacggca tgctgctgac cgacgacaag atcgacttca tcaacaagga
    10861 gatgtccaac gtcgtgctgt cgatcgacgg ccgcaaagag gtcaccgacc gggtgcgttc
    10921 gcgcgtagac ggctccggct gctacgatgt gatcatgccg aaattccaaa agcttgtaga
    10981 aaaacggggg ccgaaggact actatgtccg cggaaccttt accaaataca acctcgactt
    11041 caccaaggat gtcctgcacc tctacgacgc gggcttcgac cagatttcgg tggagccggt
    11101 cgtgtcggac ccggccctcc cctattcgat caccgaaaac gacctgccgg tcatctttga
    11161 cgagtacgag acgctggccc agaccatcct cgcctgccgc aaggcgggca gatacttcaa
    11221 cttcttccac ttcatgctgg acctcgacca gggcccctgc gcgatcaagc ggctgcgcgg
    11281 ctgcggctgc ggcaacgaat acgtcgcgat cacgccggat ggggatatct atccctgtca
    11341 tcagtttgtc ggccaggaag aatggaagat gggcaatctg gaagacggca gcttcgacaa
    11401 ggagcgcaag gcggacttcg cgacggccaa cgtctacacc aaaccggaat gtaaggaatg
    11461 ctgggcaaaa ttctactgca gcggcggctg caacgccaac aatcagaatt atgaaggcga
    11521 catccggcac gcgcacaagc tctcctgcga tctggagaaa aagcggctgg aatgcgccat
    11581 catgatcaag gcggcagagg cacagggatg aaccggcatg aattcgcctc gctcctcgac
    11641 cgcgtgatca aggagcggat gctcaagaaa attaccctca gcaaaagcgc attgccgggc
    11701 gtcgcccgca tccagatccg gccgttcgag aagggcggca gcgcgatggt gcagctctcc
    11761 aaatttcagg aggacaacaa ggtcatccat gaaaacctgc cggcggacgg cgcaggcgag
    11821 gagatcattt cgctgtttat ggatttcttc aagcagtgca acatcgtcac cgcggccggt
    11881 aactgtgaag cgaagtgcaa taagaagggt tctctgtacg tcaaaaatca aatcgatttt
    11941 tcgagacagg aaaccgcggc ggcatcctcc catgacaaac agaagcgtca ttttctgccg
    12001 ccgaatcagc cggtcgcctt cttacaggag ctaggcatca gcgggacgga cggacgggtt
    12061 tatgaccgga tggcgcacaa gctggcacag atcaaccggt ttttagagct gattgacgac
    12121 gtcaaggaca gtctgccgga aaaccggccg gtgcgcatct ttgacttgtg ctgcggcaaa
    12181 agctacctga cctttgcggt gcaccattac ttcacgcaga ttctgcatcg tcaggttgag
    12241 atggtcggcg tagatctcaa ggaggatgtc atcgagcact gcagccggac cgcggagaag
    12301 ctcgggcttg cggggcttac cttccagtgc ggcgacatcc tgcaatttga gccggacagc
    12361 aagccggata tggtcctctc gctgcacgcc tgcgacacgg cgaccgacat cgtgctgaac
    12421 acggcggtgc ggctgggaac cgggatcatc ctgtcctccc catgctgcca tcatgagctg
    12481 gcacagcagc tgcagagcga ggagctgcat ctgatcaccg attacggcat cctgcagcag
    12541 aagctctgtg agatttcaac tgacgcgctg cgcgcgcagg cgctgaagat cagcggatat
    12601 caggtacagc tgatcgagtt catcgatccg gaaaacaccc ctaaaaatct gttaatccgc
    12661 gctgtcaaaa acagaggaaa gatggacgaa gcaaaaaaga ataaactggt aaatgaatat
    12721 caatgtttat gtgagatgtt aaatgtcaat cctacgttaa agagattact caatatctga
    12781 aatcccgctt tgggatttgt aggagggtat ttaacgccat ggcagtctta tggatggtct
    12841 gcgccatctt tttatggagc accgcgctgt tggtgattgg caatgtggtt gccaatcttg
    12901 caaatatcag acatcggatg aaacaataaa agaaagagga atgcggcaga tttggtctgc
    12961 cgcatccctc tttctttttt gcttgggcat ggtgtttttt ttctgctcaa tctttgtgat
    13021 gtggtgttct ttttttattt ttcaggaatg tcttgacagg gtggtgttgt atcgctgtgg
    13081 cacagcggcc ctgccgtgtt taccaagtac cacttggcaa gtggttgtta ctcttttgcg
    13141 cggccaaaag agtaaccaga aaaggccgtt caagggggcc atacacagtg ccgcttaggg
    13201 ccagatggcc cccttgaaaa tcctctctga tatcccgcta tccccttcgg ccgcctgcgg
    13261 gcggcgtttt gcttttggca gggtggttgg gcatagctag cagcggacgc ttccccggtt
    13321 acaggttgct ctcatagtac cccaatacct aagctggttc gtaggctgat atgagactgt
    13381 gtggtttgac atcgatcact gataataccc tgcaatcttc gaaaaagcac ctcacggata
    13441 attctacagg gattcaactc tcttagacag gcacatcggg caaccaccct gtttacttag
    13501 agcacaaaac gaaaccttta ccacacagca tagaatagac cattttgcta atggattcgg
    13561 aatacagggc gagcagatat acagacttaa ccgtctatgc aacggacgtt cgaacccagc
    13621 gaacgctgtg cttccttgcc ccgctgagaa gcggacgggc agagggggtt tccaaagggg
    13681 gaatgacgtc cattcttact gtaccgaag
//
