Select genomic region:
Overview
1.1
1.2
5.1
6.1
14.1
17.1

### Identified secondary metabolite regions using strictness 'relaxed'

c00001_NZ_JAHL.. (original name was: NZ_JAHLNC010000001.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | ranthipeptide | 662,099 | 681,369 |
Region 1.2 | ranthipeptide | 995,532 | 1,016,968 |

c00005_NZ_JAHL.. (original name was: NZ_JAHLNC010000005.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 5.1 | RiPP-like | 239,146 | 246,808 |

c00006_NZ_JAHL.. (original name was: NZ_JAHLNC010000006.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 6.1 | cyanobactin | 44,573 | 67,710 | locillomycin | NRP + Polyketide | 14%

c00014_NZ_JAHL.. (original name was: NZ_JAHLNC010000014.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 14.1 | NRPS | 1 | 45,349 | equibactin | NRP | 14%

c00017_NZ_JAHL.. (original name was: NZ_JAHLNC010000017.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 17.1 | cyclic-lactone-autoinducer | 1 | 16,701 |

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | ranthipeptide | 662,099 | 681,369 |
Region 1.2 | ranthipeptide | 995,532 | 1,016,968 |
Region 5.1 | RiPP-like | 239,146 | 246,808 |
Region 6.1 | cyanobactin | 44,573 | 67,710 | locillomycin | NRP + Polyketide | 14%
Region 14.1 | NRPS | 1 | 45,349 | equibactin | NRP | 14%
Region 17.1 | cyclic-lactone-autoinducer | 1 | 16,701 |

No secondary metabolite regions were found in these records:
  c00002_NZ_JAHL.. (original name was: NZ_JAHLNC010000002.1)
  c00003_NZ_JAHL.. (original name was: NZ_JAHLNC010000003.1)
  c00004_NZ_JAHL.. (original name was: NZ_JAHLNC010000004.1)
  c00007_NZ_JAHL.. (original name was: NZ_JAHLNC010000007.1)
  c00008_NZ_JAHL.. (original name was: NZ_JAHLNC010000008.1)
  c00009_NZ_JAHL.. (original name was: NZ_JAHLNC010000009.1)
  c00010_NZ_JAHL.. (original name was: NZ_JAHLNC010000010.1)
  c00011_NZ_JAHL.. (original name was: NZ_JAHLNC010000011.1)
  c00012_NZ_JAHL.. (original name was: NZ_JAHLNC010000012.1)
  c00013_NZ_JAHL.. (original name was: NZ_JAHLNC010000013.1)
  c00015_NZ_JAHL.. (original name was: NZ_JAHLNC010000015.1)
  c00016_NZ_JAHL.. (original name was: NZ_JAHLNC010000016.1)
  c00018_NZ_JAHL.. (original name was: NZ_JAHLNC010000018.1)
  c00019_NZ_JAHL.. (original name was: NZ_JAHLNC010000019.1)
  c00020_NZ_JAHL.. (original name was: NZ_JAHLNC010000020.1)
  c00021_NZ_JAHL.. (original name was: NZ_JAHLNC010000021.1)
  c00022_NZ_JAHL.. (original name was: NZ_JAHLNC010000022.1)
  c00023_NZ_JAHL.. (original name was: NZ_JAHLNC010000023.1)
  c00024_NZ_JAHL.. (original name was: NZ_JAHLNC010000024.1)
  c00025_NZ_JAHL.. (original name was: NZ_JAHLNC010000025.1)
  c00026_NZ_JAHL.. (original name was: NZ_JAHLNC010000026.1)
  c00027_NZ_JAHL.. (original name was: NZ_JAHLNC010000027.1)
  c00028_NZ_JAHL.. (original name was: NZ_JAHLNC010000028.1)
  c00029_NZ_JAHL.. (original name was: NZ_JAHLNC010000029.1)
  c00030_NZ_JAHL.. (original name was: NZ_JAHLNC010000030.1)
  c00031_NZ_JAHL.. (original name was: NZ_JAHLNC010000031.1)
  c00032_NZ_JAHL.. (original name was: NZ_JAHLNC010000032.1)
  c00033_NZ_JAHL.. (original name was: NZ_JAHLNC010000033.1)

Compact view
c00001_NZ_JAHL.. - Region 1 - ranthipeptide
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 662,099 - 681,369 nt. (total: 19,271 nt) Show pHMM detection rules used
ranthipeptide: (TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085 or SPASM)) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716 or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or YcaO or TIGR03882)))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | ranthipeptide | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001387.1 |  | 0.17 | Other | nucleocidin | Streptomyces calvus
BGC0000599.1 |  | 0.17 | RiPP | thuricin CD α, thuricin CD β | Bacillus thuringiensis
BGC0000700.1 |  | 0.11 | Saccharide | istamycin | Streptomyces tenjimariensis
BGC0000604.1 |  | 0.09 | RiPP | GE2270A | Nonomuraea sp. WU8817
BGC0001860.1 |  | 0.09 | RiPP | thiomuracin | Thermobispora bispora DSM 43833
BGC0000613.1 |  | 0.09 | RiPP | thiomuracin A | Nonomuraea sp. Bp3714-39
BGC0001155.1 |  | 0.08 | RiPP | GE2270 | Planobispora rosea
BGC0001591.1 |  | 0.07 | Other | fatty acid enol ester | uncultured bacterium CSLC2
BGC0001688.1 |  | 0.07 | Other | N-tetradecanoyl tyrosine | uncultured bacterium CSLC2
BGC0000027.1 |  | 0.06 | Polyketide | ankaflavin, monascin, rubropunctatine, monascorubrin | Monascus pilosus

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001387.1 |  | 0.48 | Other | nucleocidin | Streptomyces calvus
BGC0000599.1 |  | 0.48 | RiPP | thuricin CD α, thuricin CD β | Bacillus thuringiensis
BGC0000700.1 |  | 0.38 | Saccharide | istamycin | Streptomyces tenjimariensis
BGC0000604.1 |  | 0.33 | RiPP | GE2270A | Nonomuraea sp. WU8817
BGC0001860.1 |  | 0.33 | RiPP | thiomuracin | Thermobispora bispora DSM 43833
BGC0000613.1 |  | 0.33 | RiPP | thiomuracin A | Nonomuraea sp. Bp3714-39
BGC0001155.1 |  | 0.32 | RiPP | GE2270 | Planobispora rosea
BGC0001591.1 |  | 0.28 | Other | fatty acid enol ester | uncultured bacterium CSLC2
BGC0001688.1 |  | 0.28 | Other | N-tetradecanoyl tyrosine | uncultured bacterium CSLC2
BGC0000027.1 |  | 0.26 | Polyketide | ankaflavin, monascin, rubropunctatine, monascorubrin | Monascus pilosus

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00001_NZ_JAHL.. - Region 2 - ranthipeptide
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 995,532 - 1,016,968 nt. (total: 21,437 nt) Show pHMM detection rules used
ranthipeptide: (TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085 or SPASM)) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716 or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or YcaO or TIGR03882)))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | ranthipeptide | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000502.1 |  | 0.19 | RiPP | cerecidin, cerecidin A1, cerecidin A2, cerecidin A3, cerecidin A4, cerecidin A5, cerecidin A6, cerecidin A7 | Bacillus cereus
BGC0000504.1 |  | 0.19 | RiPP | cytolysin ClyLl, cytolysin ClyLs | Plasmid pAD1
BGC0000500.1 |  | 0.19 | RiPP | carnolysin A1, carnolysin A2 | Carnobacterium maltaromaticum
BGC0001407.1 |  | 0.18 | RiPP | bicereucin | Bacillus cereus SJ1
BGC0000883.1 |  | 0.16 | Other | arginomycin | Streptomyces arginensis
BGC0000535.1 |  | 0.16 | RiPP | nisin A | Lactococcus lactis subsp. lactis
BGC0000551.1 |  | 0.16 | RiPP | SapB | Streptomyces coelicolor A3(2)
BGC0000547.1 |  | 0.16 | RiPP | salivaricin 9 | Streptococcus salivarius
BGC0001526.1 |  | 0.16 | Other | bartolosides E, bartolosides F, bartolosides G, bartolosides H, bartolosides I, bartolosides J, bartolosides K | Synechocystis salina LEGE 06099
BGC0001525.1 |  | 0.16 | Other | bartoloside 2, bartoloside 3, bartoloside 4 | Synechocystis salina LEGE 06155

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000502.1 |  | 0.51 | RiPP | cerecidin, cerecidin A1, cerecidin A2, cerecidin A3, cerecidin A4, cerecidin A5, cerecidin A6, cerecidin A7 | Bacillus cereus
BGC0000504.1 |  | 0.51 | RiPP | cytolysin ClyLl, cytolysin ClyLs | Plasmid pAD1
BGC0000500.1 |  | 0.51 | RiPP | carnolysin A1, carnolysin A2 | Carnobacterium maltaromaticum
BGC0001407.1 |  | 0.50 | RiPP | bicereucin | Bacillus cereus SJ1
BGC0000883.1 |  | 0.47 | Other | arginomycin | Streptomyces arginensis
BGC0000535.1 |  | 0.47 | RiPP | nisin A | Lactococcus lactis subsp. lactis
BGC0000551.1 |  | 0.46 | RiPP | SapB | Streptomyces coelicolor A3(2)
BGC0000547.1 |  | 0.46 | RiPP | salivaricin 9 | Streptococcus salivarius
BGC0001526.1 |  | 0.46 | Other | bartolosides E, bartolosides F, bartolosides G, bartolosides H, bartolosides I, bartolosides J, bartolosides K | Synechocystis salina LEGE 06099
BGC0001525.1 |  | 0.46 | Other | bartoloside 2, bartoloside 3, bartoloside 4 | Synechocystis salina LEGE 06155

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00005_NZ_JAHL.. - Region 1 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 239,146 - 246,808 nt. (total: 7,663 nt) Show pHMM detection rules used
Region on contig edge.
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

No matches found.

No matches found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
c00006_NZ_JAHL.. - Region 1 - cyanobactin
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 44,573 - 67,710 nt. (total: 23,138 nt) Show pHMM detection rules used
cyanobactin: (cyanobactin_synth or TIGR03678)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | cyanobactin | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001632.1 |  | 0.35 | RiPP | kawaguchipeptin A | Microcystis aeruginosa NIES-88
BGC0000586.1 |  | 0.19 | RiPP | microcin E492 | Klebsiella pneumoniae RYC492
BGC0000487.1 |  | 0.18 | RiPP | carnocyclin | Carnobacterium maltaromaticum
BGC0001505.1 |  | 0.17 | RiPP | anacyclamide D8P | Sphaerospermopsis sp. LEGE 00249
BGC0001933.1 |  | 0.17 | RiPP | sphaerocyclamide | Sphaerospermopsis sp. LEGE 00249
BGC0000472.1 |  | 0.17 | RiPP | anacyclamide A10 | Anabaena sp. 90
BGC0000479.1 |  | 0.17 | RiPP | prenylagaramide B, prenylagaramide C | Planktothrix agardhii NIES-596
BGC0001167.1 |  | 0.17 | RiPP | piricyclamide | Microcystis aeruginosa PCC 7005
BGC0000502.1 |  | 0.17 | RiPP | cerecidin, cerecidin A1, cerecidin A2, cerecidin A3, cerecidin A4, cerecidin A5, cerecidin A6, cerecidin A7 | Bacillus cereus
BGC0001222.1 |  | 0.17 | RiPP | acidocin B | Lactobacillus acidophilus

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001632.1 |  | 0.68 | RiPP | kawaguchipeptin A | Microcystis aeruginosa NIES-88
BGC0000586.1 |  | 0.50 | RiPP | microcin E492 | Klebsiella pneumoniae RYC492
BGC0000487.1 |  | 0.49 | RiPP | carnocyclin | Carnobacterium maltaromaticum
BGC0001505.1 |  | 0.49 | RiPP | anacyclamide D8P | Sphaerospermopsis sp. LEGE 00249
BGC0001933.1 |  | 0.49 | RiPP | sphaerocyclamide | Sphaerospermopsis sp. LEGE 00249
BGC0000472.1 |  | 0.49 | RiPP | anacyclamide A10 | Anabaena sp. 90
BGC0000479.1 |  | 0.49 | RiPP | prenylagaramide B, prenylagaramide C | Planktothrix agardhii NIES-596
BGC0001167.1 |  | 0.48 | RiPP | piricyclamide | Microcystis aeruginosa PCC 7005
BGC0000502.1 |  | 0.48 | RiPP | cerecidin, cerecidin A1, cerecidin A2, cerecidin A3, cerecidin A4, cerecidin A5, cerecidin A6, cerecidin A7 | Bacillus cereus
BGC0001222.1 |  | 0.48 | RiPP | acidocin B | Lactobacillus acidophilus

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00014_NZ_JAHL.. - Region 1 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1 - 45,349 nt. (total: 45,349 nt) Show pHMM detection rules used
Region on contig edge.
NRPS: cds(Condensation and (AMP-binding or A-OX))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
NRPS/PKS modules
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | NRPS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000373.1 |  | 0.24 | NRP | holomycin | Streptomyces clavuligerus ATCC 27064
BGC0000412.1 |  | 0.24 | NRP | pyochelin | Pseudomonas aeruginosa PAO1
BGC0000410.1 |  | 0.21 | NRP | pseudomonine | Pseudomonas fluorescens
BGC0001636.1 |  | 0.21 | NRP | KK-1 | Curvularia clavata
BGC0001825.1 |  | 0.21 | NRP | xenematide | Xenorhabdus nematophila AN6/1
BGC0001641.1 |  | 0.20 | NRP | kolossin | Photorhabdus laumondii subsp. laumondii TTO1
BGC0001615.1 |  | 0.20 | NRP | hexose-palythine-serine, hexose-shinorine | Heteroscytonema crispum UCFS10
BGC0001479.1 |  | 0.20 | NRP | anabaenopeptin NZ857, nostamide A | Nostoc punctiforme PCC 73102
BGC0001560.1 |  | 0.20 | NRP, Polyketide | cryptomaldamide | Moorea producens JHB
BGC0001131.1 |  | 0.20 | NRP | ambactin | Xenorhabdus miraniensis

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000373.1 |  | 0.57 | NRP | holomycin | Streptomyces clavuligerus ATCC 27064
BGC0000412.1 |  | 0.57 | NRP | pyochelin | Pseudomonas aeruginosa PAO1
BGC0000410.1 |  | 0.54 | NRP | pseudomonine | Pseudomonas fluorescens
BGC0001636.1 |  | 0.54 | NRP | KK-1 | Curvularia clavata
BGC0001825.1 |  | 0.54 | NRP | xenematide | Xenorhabdus nematophila AN6/1
BGC0001641.1 |  | 0.53 | NRP | kolossin | Photorhabdus laumondii subsp. laumondii TTO1
BGC0001615.1 |  | 0.53 | NRP | hexose-palythine-serine, hexose-shinorine | Heteroscytonema crispum UCFS10
BGC0001479.1 |  | 0.53 | NRP | anabaenopeptin NZ857, nostamide A | Nostoc punctiforme PCC 73102
BGC0001560.1 |  | 0.53 | NRP, Polyketide | cryptomaldamide | Moorea producens JHB
BGC0001131.1 |  | 0.53 | NRP | ambactin | Xenorhabdus miraniensis

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Module view
Shows module structures for each candidate in NRPS- and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here.
Legend
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 0 - 45349:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (cys - Me-cys) + (Me-cys)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg14_10: cys
  Search NORINE for peptide: strict or relaxed
  AMP-binding (535..931): cys
  NRPSPredictor2: cys
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      cys
    Small clusters prediction:
      cys
    Single AA prediction:
      cys
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DLYNLSLIWK
    Nearest Stachelhaus code:
      cys
    Stachelhaus code match:
      100% (strong)
ctg14_13: cys - cys
  Search NORINE for peptide: strict or relaxed
  AMP-binding (568..967): cys
  NRPSPredictor2: cys
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      cys
    Small clusters prediction:
      cys
    Single AA prediction:
      cys
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DLYNMSMIWK
    Nearest Stachelhaus code:
      cys
    Stachelhaus code match:
      100% (strong)
  AMP-binding (1646..2046): cys
  NRPSPredictor2: cys
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      cys
    Small clusters prediction:
      cys
    Single AA prediction:
      cys
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DLYNLSLIWK
    Nearest Stachelhaus code:
      cys
    Stachelhaus code match:
      100% (strong)
ctg14_14: dhb
  Search NORINE for peptide: strict or relaxed
  AMP-binding (31..433): dhb
  NRPSPredictor2: dhb
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aromatic
    Large clusters prediction:
      dhb, sal
    Small clusters prediction:
      dhb, sal
    Single AA prediction:
      dhb
  Stachelhaus prediction details:
    Stachelhaus sequence:
      aLPsQGVICK
    Nearest Stachelhaus code:
      sal
    Stachelhaus code match:
      80% (moderate)

c00017_NZ_JAHL.. - Region 1 - cyclic-lactone-autoinducer
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1 - 16,701 nt. (total: 16,701 nt) Show pHMM detection rules used
Region on contig edge.
cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | cyclic-lactone-autoinducer | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001586.1 |  | 0.14 | Saccharide | EPS273 | Pseudomonas stutzeri
BGC0001488.1 |  | 0.13 | Other | 4-formylaminooxyvinylglycine | Pseudomonas fluorescens WH6
BGC0001560.1 |  | 0.11 | NRP, Polyketide | cryptomaldamide | Moorea producens JHB
BGC0001686.1 |  | 0.08 | NRP | N-octanoyl-Met-Phe-H | Clostridium sp. CAG:567
BGC0000343.1 |  | 0.06 | NRP | enterobactin | Pseudomonas sp. J465
BGC0000721.1 |  | 0.06 | Saccharide | tobramycin | Streptoalloteichus tenebrarius
BGC0000172.1 |  | 0.06 | Polyketide | basiliskamide A, basiliskamide B | Brevibacillus laterosporus PE36
BGC0000381.1 |  | 0.06 | NRP | lichenysin | Bacillus licheniformis DSM 13 = ATCC 14580
BGC0000433.1 |  | 0.05 | NRP | surfactin | Bacillus velezensis FZB42
BGC0000993.1 |  | 0.05 | NRP, Polyketide | FR901228 | Chromobacterium violaceum

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001586.1 |  | 0.44 | Saccharide | EPS273 | Pseudomonas stutzeri
BGC0001488.1 |  | 0.41 | Other | 4-formylaminooxyvinylglycine | Pseudomonas fluorescens WH6
BGC0001560.1 |  | 0.38 | NRP, Polyketide | cryptomaldamide | Moorea producens JHB
BGC0001686.1 |  | 0.30 | NRP | N-octanoyl-Met-Phe-H | Clostridium sp. CAG:567
BGC0000343.1 |  | 0.26 | NRP | enterobactin | Pseudomonas sp. J465
BGC0000721.1 |  | 0.25 | Saccharide | tobramycin | Streptoalloteichus tenebrarius
BGC0000172.1 |  | 0.25 | Polyketide | basiliskamide A, basiliskamide B | Brevibacillus laterosporus PE36
BGC0000381.1 |  | 0.24 | NRP | lichenysin | Bacillus licheniformis DSM 13 = ATCC 14580
BGC0000433.1 |  | 0.23 | NRP | surfactin | Bacillus velezensis FZB42
BGC0000993.1 |  | 0.21 | NRP, Polyketide | FR901228 | Chromobacterium violaceum

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names