LOCUS       NZ_CM000753.1          22826 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CM000753.1 Bacillus thuringiensis serovar berliner ATCC 10792
            chromosome, whole genome shotgun sequence.
ACCESSION   NZ_CM000753
VERSION     NZ_CM000753.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 14:59:36
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 5832953
            Orig. end    :: 5855779
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22826
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5842953:5845779](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12826
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     cand_cluster    1..22826
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..22826
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="14"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     CDS             79..963
                     /locus_tag="ctg1_5927"
                     /transl_table=11
                     /translation="MEIRKKLVDSSKYAIKCPNAMKPEFITVHNTYNDASAENEISYMI
                     GNNNAVSFHVAVDDKEAVQGIPFDRNAWHAGDGNGNGNRKSIGVEICYSLSGGDRYYKA
                     EDNAAIVIAQLMKQFNIPISNVRTHKSWSGKHCPHRMLDEGRLDQFIEKVNKAFNNNNN
                     KPIQPVGLGIAVNKYPNNGGINLYSQPQGGYFTRVIYDKTPYLIIDAAWYENPMICLGN
                     EAWAALEHFDVQWFSAYSKYPPGGGINTYDGPNGNYTGFVDGSVPYRILARKDGYLAIG
                     NNAWVKEEHFDVR"
     PFAM_domain     139..495
                     /aSDomain="Amidase_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01510.27"
                     /description="N-acetylmuramoyl-L-alanine amidase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_5927_0499"
                     /evalue="2.00E-18"
                     /label="ctg1_5927"
                     /locus_tag="ctg1_5927"
                     /protein_end="139"
                     /protein_start="20"
                     /score="67.1"
                     /tool="antismash"
                     /translation="MKPEFITVHNTYNDASAENEISYMIGNNNAVSFHVAVDDKEAVQG
                     IPFDRNAWHAGDGNGNGNRKSIGVEICYSLSGGDRYYKAEDNAAIVIAQLMKQFNIPIS
                     NVRTHKSWSGKHCPH"
     CDS             1154..1390
                     /locus_tag="ctg1_5928"
                     /transl_table=11
                     /translation="MDSLQEVKGDVQEIRQDIKEIRLEIRSLEMRTTGNEKDIININKQ
                     LDKISANTTWILRLIIGGLIGAALTFFLKGGGM"
     PFAM_domain     1169..1366
                     /aSDomain="XhlA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10779.11"
                     /description="Haemolysin XhlA"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_5928_0500"
                     /evalue="2.70E-13"
                     /label="ctg1_5928"
                     /locus_tag="ctg1_5928"
                     /protein_end="71"
                     /protein_start="5"
                     /score="50.0"
                     /tool="antismash"
                     /translation="EVKGDVQEIRQDIKEIRLEIRSLEMRTTGNEKDIININKQLDKIS
                     ANTTWILRLIIGGLIGAALTF"
     CDS             1390..1629
                     /locus_tag="ctg1_5929"
                     /transl_table=11
                     /translation="MIEITAMIGVVVGISQIAKTTGLQTKYIPLFNLTLGITLGVLFLS
                     QDIKMNLFQGMIIGLSASGLFDHTKIIKRDADRK"
     CDS             1626..2681
                     /locus_tag="ctg1_5930"
                     /transl_table=11
                     /translation="MKKKYKHILSIVVAIILVVSIGTNALADRTLLIPDLPKQPYRYGV
                     GAYEGVVAHSTATPEAPAINIQKYESRTWRSAFVHYAVDWNEKIQIASTKHQAWGAGPA
                     ANARFVHVELCETSDPLKFKRSYEKYIELIAEILRERNIHPSKGLWTHRDITYKLGGTD
                     HEDPLAYLRSHGVSEAKFRADVLKVYNGSTVTVDTKPQKPNEISGTVESNGIAYIEGYN
                     VNLRSGPSTENSVIRKLQKGEAYKVWNKLGNWLHFGGNQWIYYNSSYIRCQGNEPATVI
                     GKRVISKVNNLRFYDSPSWQDKDVAGTVDMGLGFIIDTKVIVNNSPQYRVHNSKGKTYY
                     VTANEAYVYVK"
     PFAM_domain     1770..2126
                     /aSDomain="Amidase_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01510.27"
                     /description="N-acetylmuramoyl-L-alanine amidase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_5930_0501"
                     /evalue="3.00E-12"
                     /label="ctg1_5930"
                     /locus_tag="ctg1_5930"
                     /protein_end="167"
                     /protein_start="48"
                     /score="47.2"
                     /tool="antismash"
                     /translation="EGVVAHSTATPEAPAINIQKYESRTWRSAFVHYAVDWNEKIQIAS
                     TKHQAWGAGPAANARFVHVELCETSDPLKFKRSYEKYIELIAEILRERNIHPSKGLWTH
                     RDITYKLGGTDHEDP"
     CDS             3002..3577
                     /locus_tag="ctg1_5931"
                     /transl_table=11
                     /translation="MPKWAKRIAMFMIFICSILTIDALVGSKKGIKAITAAVEELTADE
                     KNIGNQKEVKQGAETSDYKHLDKQHYAWVMDDYLKDLSDVANRFSILEADAEIKGTINK
                     SWVSDVGDVFYKMSYLISSVRYVEPPTELKGLHSSILKAMDNLQFVIDNYGDAASQTDL
                     AKLGKCLKSLRSARDTIDEVRSELSTYE"
     CDS             complement(3752..3958)
                     /gene="allorf_5836705_5836911"
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="allorf_5836705_5836911"
                     /protein_id="allorf_5836705_5836911"
                     /tool="antismash"
                     /transl_table=1
                     /translation="VVSSSSPLILNVSFGFVITQTTISSLMTVVALSNTKSIKSIYIIL
                     MILFPRIPSFSFKISLSSCQPCP"
     CDS_motif       complement(3911..3958)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: VVSSSSPLILNVSFGF"
                     /locus_tag="allorf_5836705_5836911_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(3752..3910)
                     /prepeptide="core"
                     /locus_tag="allorf_5836705_5836911_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.30"
                     /molecular_weight="5449.6"
                     /monoisotopic_mass="5446.1"
                     /core_sequence="VITQTTISSLMTVVALSNTKSIKSIYIILMILFPRIPSFSFKI
                     SLSSCQPCP"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="VVSSSSPLILNVSFGF"
                     /leader_location="[3910:3958](-)"
                     /alternative_weights="5467.6"
                     /alternative_weights="5485.6"
                     /alternative_weights="5503.6"
                     /alternative_weights="5521.7"
                     /alternative_weights="5539.7"
                     /alternative_weights="5557.7"
                     /alternative_weights="5575.7"
                     /alternative_weights="5593.7"
                     /alternative_weights="5611.8"
                     /alternative_weights="5629.8"
                     /alternative_weights="5647.8"
                     /alternative_weights="5665.8"
                     /alternative_weights="5683.8"
     CDS             complement(4291..4503)
                     /gene="allorf_5837244_5837456"
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="allorf_5837244_5837456"
                     /protein_id="allorf_5837244_5837456"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MGVMDKRKDTLRCPPPTYKSNLYFIHFIQYGDDGLCIALEPNHAI
                     SISGHHNIQNQSFIVFRQKTPSSKM"
     CDS_motif       complement(4411..4503)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MGVMDKRKDTLRCPPPTYKSNLYFIHFIQYG"
                     /locus_tag="allorf_5837244_5837456_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(4291..4410)
                     /prepeptide="core"
                     /locus_tag="allorf_5837244_5837456_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.20"
                     /molecular_weight="4226.7"
                     /monoisotopic_mass="4224.2"
                     /core_sequence="DDGLCIALEPNHAISISGHHNIQNQSFIVFRQKTPSSKM"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MGVMDKRKDTLRCPPPTYKSNLYFIHFIQYG"
                     /leader_location="[4410:4503](-)"
                     /alternative_weights="4244.7"
                     /alternative_weights="4262.8"
                     /alternative_weights="4280.8"
                     /alternative_weights="4298.8"
                     /alternative_weights="4316.8"
     CDS             4635..5261
                     /locus_tag="ctg1_5932"
                     /transl_table=11
                     /translation="LFDIQKVLLDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXW
                     FQEGDAWYYLDANQGGSMVTGQATIEGKTYTFAADGKWSESESSGIIDLALKQLGKPYV
                     FGNSGPNSFDCSGFIYYVFKNNGYNIGRTSVAGYWGMVTKISNPQPGDLVFLQNTYKAG
                     PSHMGIYLGNGEFIHAADERTGVTKGNVNSQYNREHFLGYGRFTK"
     PFAM_domain     4932..5243
                     /aSDomain="NLPC_P60"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00877.21"
                     /description="NlpC/P60 family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_5932_0502"
                     /evalue="2.30E-24"
                     /label="ctg1_5932"
                     /locus_tag="ctg1_5932"
                     /protein_end="203"
                     /protein_start="99"
                     /score="85.5"
                     /tool="antismash"
                     /translation="GKPYVFGNSGPNSFDCSGFIYYVFKNNGYNIGRTSVAGYWGMVTK
                     ISNPQPGDLVFLQNTYKAGPSHMGIYLGNGEFIHAADERTGVTKGNVNSQYNREHFLGY
                     "
     CDS             5440..5817
                     /locus_tag="ctg1_5933"
                     /transl_table=11
                     /translation="MVHHILQIIVCLLFLNKFLHLKEVNIMVCIPSIVHQKASPKVYKT
                     PHHPHFIKGGNIEIWKIALATSAAPTYLSAAVIDDNECKIDGGLWANNPVLVAIAEAVK
                     LGYSLEQIKVLSIGTGTSLSF"
     PFAM_domain     6247..6738
                     /aSDomain="PALP"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00291.27"
                     /description="Pyridoxal-phosphate dependent enzyme"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_5934_0503"
                     /evalue="7.90E-25"
                     /label="ctg1_5934"
                     /locus_tag="ctg1_5934"
                     /protein_end="164"
                     /protein_start="0"
                     /score="88.0"
                     /tool="antismash"
                     /translation="VKELLNTIPNAYWTNQYNNADNFEAHYQGIGGEISNDFKQLDYAF
                     IGVSTGGTIAGVSTRLKEKFPNIKIIAVDSQGSIIFGDKPRKRYIPEIGASMITGMVKK
                     ALIDDVMIVPEVHTVSGCYELFNKHEIFAGGSSGTSYYAIQKYFENRDVQNTPNVVFLC
                     P"
     CDS             6247..6837
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1081:cysteine synthase (Score: 217.8; E-value:
                     2.7e-66)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_5934"
                     /transl_table=11
                     /translation="VKELLNTIPNAYWTNQYNNADNFEAHYQGIGGEISNDFKQLDYAF
                     IGVSTGGTIAGVSTRLKEKFPNIKIIAVDSQGSIIFGDKPRKRYIPEIGASMITGMVKK
                     ALIDDVMIVPEVHTVSGCYELFNKHEIFAGGSSGTSYYAIQKYFENRDVQNTPNVVFLC
                     PDNGQAYTSTIYNVEWVEWLNTQKSVEDQLVSL"
     aSDomain        6865..7830
                     /aSDomain="TIGR03944"
                     /aSTool="tigrfam"
                     /description="dehyd_SbnB_fam: 2,3-diaminopropionate
                     biosynthesis protein SbnB"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_5935_0099"
                     /evalue="5.50E-105"
                     /identifier="TIGR03944"
                     /label="ctg1_5935"
                     /locus_tag="ctg1_5935"
                     /protein_end="322"
                     /protein_start="0"
                     /score="348.9"
                     /tool="antismash"
                     /translation="MMYLNTKHINEMGVNWEETINAISKAVKSLDSEDFSQPIKPYLRF
                     DDPANRIIAMPAYIGGEFKVSGIKWIASFPKNIEKGIQRAHSVTILNDAMTGKPFATLN
                     TAMVSVIRTASVTGLMIREFAKLRDLNNVKVGIIGFGPIGQMHLKMVTALLGDKIESVY
                     LYDINGIKDELIPEEIYSKTQKVNAYEEAYNDADIFITCTVSAEGYIDKKPKDGALLLN
                     VSLRDFKPDILEYTKSLVVDNWEEVCREKTDVERMHLERGLQKEDTVSIADVVIRGALQ
                     NFPYDKAILFNPMGMAIFDVAIAAYYYQRARENEMGVLLED"
     CDS             6865..7833
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1158:ornithine cyclodeaminase (Score: 368.6; E-value:
                     3.4e-112)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_5935"
                     /transl_table=11
                     /translation="MMYLNTKHINEMGVNWEETINAISKAVKSLDSEDFSQPIKPYLRF
                     DDPANRIIAMPAYIGGEFKVSGIKWIASFPKNIEKGIQRAHSVTILNDAMTGKPFATLN
                     TAMVSVIRTASVTGLMIREFAKLRDLNNVKVGIIGFGPIGQMHLKMVTALLGDKIESVY
                     LYDINGIKDELIPEEIYSKTQKVNAYEEAYNDADIFITCTVSAEGYIDKKPKDGALLLN
                     VSLRDFKPDILEYTKSLVVDNWEEVCREKTDVERMHLERGLQKEDTVSIADVVIRGALQ
                     NFPYDKAILFNPMGMAIFDVAIAAYYYQRARENEMGVLLED"
     PFAM_domain     6904..7806
                     /aSDomain="OCD_Mu_crystall"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02423.17"
                     /description="Ornithine cyclodeaminase/mu-crystallin
                     family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_5935_0504"
                     /evalue="6.00E-33"
                     /label="ctg1_5935"
                     /locus_tag="ctg1_5935"
                     /protein_end="314"
                     /protein_start="13"
                     /score="114.2"
                     /tool="antismash"
                     /translation="VNWEETINAISKAVKSLDSEDFSQPIKPYLRFDDPANRIIAMPAY
                     IGGEFKVSGIKWIASFPKNIEKGIQRAHSVTILNDAMTGKPFATLNTAMVSVIRTASVT
                     GLMIREFAKLRDLNNVKVGIIGFGPIGQMHLKMVTALLGDKIESVYLYDINGIKDELIP
                     EEIYSKTQKVNAYEEAYNDADIFITCTVSAEGYIDKKPKDGALLLNVSLRDFKPDILEY
                     TKSLVVDNWEEVCREKTDVERMHLERGLQKEDTVSIADVVIRGALQNFPYDKAILFNPM
                     GMAIFDVAIAAYYYQRAREN"
     CDS             7966..8739
                     /locus_tag="ctg1_5936"
                     /transl_table=11
                     /translation="MSEIISALDLLHPKQIRFHESYEHKRLEQICRVMEREGVLRNPPL
                     VSELSDGNYLLLDGAHRMKAMMALGCKRVAVQVVPDEKIKIRAWNHLLPMGEWVNNLKK
                     EPTIIWSGKIIANKRLLAKITEANKQEHFLYARDLNSDLFNHLEIWHRIVGLYQHEYTV
                     RRHSNDTEVWPHSNEILMSYPEYSLMELKKVIEAKFLMPAGVTRTTLSGRLLNLRIPLH
                     ILRTEVYPAGEWETLCGNWSKCLRLYDEPIYVYDA"
     PFAM_domain     7990..8211
                     /aSDomain="ParBc"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02195.20"
                     /description="ParB-like nuclease domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_5936_0505"
                     /evalue="2.80E-08"
                     /label="ctg1_5936"
                     /locus_tag="ctg1_5936"
                     /protein_end="82"
                     /protein_start="8"
                     /score="33.9"
                     /tool="antismash"
                     /translation="DLLHPKQIRFHESYEHKRLEQICRVMEREGVLRNPPLVSELSDGN
                     YLLLDGAHRMKAMMALGCKRVAVQVVPDE"
     CDS             8889..9131
                     /locus_tag="ctg1_5937"
                     /transl_table=11
                     /translation="MGVNITKKDKVEISKKLKVFLADQYSLELGDYISFEILEFIIKEL
                     NPHFNQATKNRLEILLKNIEKEIYSELVSHGNNKA"
     PFAM_domain     8898..9092
                     /aSDomain="DUF2164"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09932.11"
                     /description="Uncharacterized conserved protein (DUF2164)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_5937_0506"
                     /evalue="6.10E-06"
                     /label="ctg1_5937"
                     /locus_tag="ctg1_5937"
                     /protein_end="68"
                     /protein_start="3"
                     /score="26.3"
                     /tool="antismash"
                     /translation="NITKKDKVEISKKLKVFLADQYSLELGDYISFEILEFIIKELNPH
                     FNQATKNRLEILLKNIEKEI"
     CDS             9742..9909
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) L_biotic_A"
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_5938"
                     /sec_met_domain="L_biotic_A (E-value: 2.1e-12, bitscore:
                     45.3, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDNEKYLQVVEDEELEQLVGGIGPGWVETLTKDCPWNMPVACVTI
                     MGQRICKKCR"
     CDS_motif       9742..9804
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MDNEKYLQVVEDEELEQLVGG"
                     /locus_tag="ctg1_5938_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9805..9909
                     /prepeptide="core"
                     /locus_tag="ctg1_5938_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="2.90"
                     /molecular_weight="3781.6"
                     /monoisotopic_mass="3778.9"
                     /core_sequence="IGPGWVETLTKDCPWNMPVACVTIMGQRICKKCR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MDNEKYLQVVEDEELEQLVGG"
                     /leader_location="[9741:9804](+)"
     PFAM_domain     9754..9855
                     /aSDomain="L_biotic_typeA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04604.15"
                     /description="Type-A lantibiotic"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_5938_0507"
                     /evalue="6.20E-12"
                     /label="ctg1_5938"
                     /locus_tag="ctg1_5938"
                     /protein_end="38"
                     /protein_start="4"
                     /score="45.3"
                     /tool="antismash"
                     /translation="KYLQVVEDEELEQLVGGIGPGWVETLTKDCPWNM"
     CDS             10001..12826
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070:lanthionine synthetase C family protein (Score:
                     686.7; E-value: 8.9e-208)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_5939"
                     /sec_met_domain="LANC_like (E-value: 3.2e-35, bitscore:
                     120.1, seeds: 47, tool: rule-based-clusters)"
                     /sec_met_domain="DUF4135 (E-value: 1.9e-79, bitscore:
                     266.1, seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNNSHGILNTIDNGASLVTKEDLEKNFGIFLEGFSFNDIIKNDE
                     NYNFQKIIQTYVVFSKNMIKNKIDFFGNVERISESIMFDLERRLYQVLRPSLIVYINKL
                     RVENVLIGMDSGEEYKYFTKNFFHFKRFYINFFKILPLLNEKIFKIIENEINYMIWLQG
                     TLEKDQKEIHKMSTFNVMHVEKVTNLGDYHNNGKRTILLEDKFNNKVILKPVDLKNSIL
                     YHSLINQLNKDLNTNIFIPQVVNKRNYGYMEYINHESCESTEQIKDYYYNLGVVLSVMY
                     LINGSDIHNENIIAKQSSPVIIDFETLGSTLNPSITEETSSFILSNSVLNSRMLPIKFS
                     GGREVIRDYSAIGRVMQNLVKTIKIKNEFTSNPIEIKEETIVEDTVQNLPFFNGDIYEY
                     DNYIKDIIKGFEDAYNTVLKNKKEYVYILKNSVSKWNYRKVYRNTKVYSLLLDRLNVPD
                     LLENKSKTIKYLKNILEKNIYLATRKDIIQKEIEALLSYDVPYFFNKYEWGSYESLSSN
                     EIDLEMKFKKISYADFLLQRKIIEISLSNQNDNLYKLNTVKETINFQTNLPTNKIREAI
                     TEKILDGCYISKNGDVDFIGLKTNWQGELEINHLNNGIYDGVLGISTLLRNNADPNHIE
                     IINKLEQKALQEILNRNKNNYGFVNGVNAIISYYLTNSPYKTYIDEKVVLQIFMDINSD
                     IEKGRYNDKHFDILGGSAGLVLTAVKFYQVNPKYKILLKVAENLGDYIVNNMQTNDEFL
                     YWKAHDTLNLEDSLKGFVHGLSGQLLALYKLKDILKTNKYDRVIHGIHKSEKVSMSEYE
                     YTDSWCKGFSGMGISRIKILESYQNEDIQSDLIFFKNQILSKLHVNSDYCLCHGLMGKL
                     DFLLELENRGMLEQNEKQIVMKVTNNFLNNFDIEDYNPHKIALFTGLGSILYFLQRLEN
                     NKLNSILYFNA"
     aSDomain        10154..12790
                     /aSDomain="TIGR03897"
                     /aSTool="tigrfam"
                     /description="lanti_2_LanM: type 2 lantibiotic biosynthesis
                     protein LanM"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_5939_0100"
                     /evalue="1.20E-193"
                     /identifier="TIGR03897"
                     /label="ctg1_5939"
                     /locus_tag="ctg1_5939"
                     /protein_end="930"
                     /protein_start="51"
                     /score="643.4"
                     /tool="antismash"
                     /translation="IIQTYVVFSKNMIKNKIDFFGNVERISESIMFDLERRLYQVLRPS
                     LIVYINKLRVENVLIGMDSGEEYKYFTKNFFHFKRFYINFFKILPLLNEKIFKIIENEI
                     NYMIWLQGTLEKDQKEIHKMSTFNVMHVEKVTNLGDYHNNGKRTILLEDKFNNKVILKP
                     VDLKNSILYHSLINQLNKDLNTNIFIPQVVNKRNYGYMEYINHESCESTEQIKDYYYNL
                     GVVLSVMYLINGSDIHNENIIAKQSSPVIIDFETLGSTLNPSITEETSSFILSNSVLNS
                     RMLPIKFSGGREVIRDYSAIGRVMQNLVKTIKIKNEFTSNPIEIKEETIVEDTVQNLPF
                     FNGDIYEYDNYIKDIIKGFEDAYNTVLKNKKEYVYILKNSVSKWNYRKVYRNTKVYSLL
                     LDRLNVPDLLENKSKTIKYLKNILEKNIYLATRKDIIQKEIEALLSYDVPYFFNKYEWG
                     SYESLSSNEIDLEMKFKKISYADFLLQRKIIEISLSNQNDNLYKLNTVKETINFQTNLP
                     TNKIREAITEKILDGCYISKNGDVDFIGLKTNWQGELEINHLNNGIYDGVLGISTLLRN
                     NADPNHIEIINKLEQKALQEILNRNKNNYGFVNGVNAIISYYLTNSPYKTYIDEKVVLQ
                     IFMDINSDIEKGRYNDKHFDILGGSAGLVLTAVKFYQVNPKYKILLKVAENLGDYIVNN
                     MQTNDEFLYWKAHDTLNLEDSLKGFVHGLSGQLLALYKLKDILKTNKYDRVIHGIHKSE
                     KVSMSEYEYTDSWCKGFSGMGISRIKILESYQNEDIQSDLIFFKNQILSKLHVNSDYCL
                     CHGLMGKLDFLLELENRGMLEQNEKQIVMKVTNNFLNNFDIEDYNPHKIALFTGLGSIL
                     YFLQRLEN"
     PFAM_domain     10421..11509
                     /aSDomain="DUF4135"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13575.8"
                     /description="Domain of unknown function (DUF4135)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_5939_0508"
                     /evalue="2.30E-74"
                     /label="ctg1_5939"
                     /locus_tag="ctg1_5939"
                     /protein_end="503"
                     /protein_start="140"
                     /score="251.0"
                     /tool="antismash"
                     /translation="PLLNEKIFKIIENEINYMIWLQGTLEKDQKEIHKMSTFNVMHVEK
                     VTNLGDYHNNGKRTILLEDKFNNKVILKPVDLKNSILYHSLINQLNKDLNTNIFIPQVV
                     NKRNYGYMEYINHESCESTEQIKDYYYNLGVVLSVMYLINGSDIHNENIIAKQSSPVII
                     DFETLGSTLNPSITEETSSFILSNSVLNSRMLPIKFSGGREVIRDYSAIGRVMQNLVKT
                     IKIKNEFTSNPIEIKEETIVEDTVQNLPFFNGDIYEYDNYIKDIIKGFEDAYNTVLKNK
                     KEYVYILKNSVSKWNYRKVYRNTKVYSLLLDRLNVPDLLENKSKTIKYLKNILEKNIYL
                     ATRKDIIQKEIEALLSYDVPYFF"
     PFAM_domain     11831..12802
                     /aSDomain="LANC_like"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05147.15"
                     /description="Lanthionine synthetase C-like protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_5939_0509"
                     /evalue="6.30E-33"
                     /label="ctg1_5939"
                     /locus_tag="ctg1_5939"
                     /protein_end="934"
                     /protein_start="610"
                     /score="113.9"
                     /tool="antismash"
                     /translation="NNGIYDGVLGISTLLRNNADPNHIEIINKLEQKALQEILNRNKNN
                     YGFVNGVNAIISYYLTNSPYKTYIDEKVVLQIFMDINSDIEKGRYNDKHFDILGGSAGL
                     VLTAVKFYQVNPKYKILLKVAENLGDYIVNNMQTNDEFLYWKAHDTLNLEDSLKGFVHG
                     LSGQLLALYKLKDILKTNKYDRVIHGIHKSEKVSMSEYEYTDSWCKGFSGMGISRIKIL
                     ESYQNEDIQSDLIFFKNQILSKLHVNSDYCLCHGLMGKLDFLLELENRGMLEQNEKQIV
                     MKVTNNFLNNFDIEDYNPHKIALFTGLGSILYFLQRLENNKLN"
     CDS             12841..14943
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 184.6; E-value:
                     5.2e-56)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_5940"
                     /sec_met_domain="Peptidase_C39 (E-value: 1.1e-29, bitscore:
                     101.4, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLRKKIKFIPQMTSFDCGPSCLAMVMHYYGLAVQASEIRNSKIIN
                     KKSSWSLLDIKKVSESYGLSATAYRIENTADLKWIQKPMIAFWGFNHFVIIERVKENKF
                     YIVDPKAGPMVIDIRSFEEMFCNYILVIENKEDIQPDIKRREKHILLRYIDHFVSPSQM
                     ILLALLTLLAQISIFTFPFILKKFMDILNASKEVDVRYLLIILGSLIVVIGIKSITSII
                     KVRFQKEIDRKSTTKVFEHMFNIPIEKITSRHAGDLNVRIMSLESIRGYILEDLIEMII
                     SIVVIIPLLMYLLYTETFYTLILMFFIASSLFINISLGKFIYNANLVETYYLGEHRGKI
                     NESLKAMYYVKATGIFSKIKSVWKKDYNKYLDTVHKRVLKQNALESFNSSLSTIFIIIM
                     LAVGFYNFSKGEGDLSNIFFFIAISSIIFSPVSTIIGSILNWNSVKPILLRTLDILEEE
                     LEIDRSDTKVNILRGSIQFNNISFSFDDKKIIENLSLNIKNNESIAIVGESGSGKSTLA
                     NLLLKLHTPDKGNILIDNRDIKDWNSEELRKKVGLMTQDGVLFRGSLSENLSYFDINYD
                     PSKIQNAILKLNLSNYIQFQSINDIFISEGGTNFSGGQRQRLAMLRLFMKEYPILILDE
                     PTNHLDRETANTVIENIFAMPSTKIIITHDENILERVDKVYELTDKKLEQREIFSKPQL
                     QTSGKG"
     PFAM_domain     12856..13248
                     /aSDomain="Peptidase_C39"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03412.17"
                     /description="Peptidase C39 family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_5940_0510"
                     /evalue="3.40E-29"
                     /label="ctg1_5940"
                     /locus_tag="ctg1_5940"
                     /protein_end="136"
                     /protein_start="5"
                     /score="101.4"
                     /tool="antismash"
                     /translation="IKFIPQMTSFDCGPSCLAMVMHYYGLAVQASEIRNSKIINKKSSW
                     SLLDIKKVSESYGLSATAYRIENTADLKWIQKPMIAFWGFNHFVIIERVKENKFYIVDP
                     KAGPMVIDIRSFEEMFCNYILVIENKE"
     PFAM_domain     13327..14133
                     /aSDomain="ABC_membrane"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00664.25"
                     /description="ABC transporter transmembrane region"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_5940_0511"
                     /evalue="1.40E-20"
                     /label="ctg1_5940"
                     /locus_tag="ctg1_5940"
                     /protein_end="431"
                     /protein_start="162"
                     /score="74.2"
                     /tool="antismash"
                     /translation="MILLALLTLLAQISIFTFPFILKKFMDILNASKEVDVRYLLIILG
                     SLIVVIGIKSITSIIKVRFQKEIDRKSTTKVFEHMFNIPIEKITSRHAGDLNVRIMSLE
                     SIRGYILEDLIEMIISIVVIIPLLMYLLYTETFYTLILMFFIASSLFINISLGKFIYNA
                     NLVETYYLGEHRGKINESLKAMYYVKATGIFSKIKSVWKKDYNKYLDTVHKRVLKQNAL
                     ESFNSSLSTIFIIIMLAVGFYNFSKGEGDLSNIFFFIAISSIIFSPV"
     PFAM_domain     14311..14754
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_5940_0512"
                     /evalue="2.80E-33"
                     /label="ctg1_5940"
                     /locus_tag="ctg1_5940"
                     /protein_end="638"
                     /protein_start="490"
                     /score="115.4"
                     /tool="antismash"
                     /translation="ENLSLNIKNNESIAIVGESGSGKSTLANLLLKLHTPDKGNILIDN
                     RDIKDWNSEELRKKVGLMTQDGVLFRGSLSENLSYFDINYDPSKIQNAILKLNLSNYIQ
                     FQSINDIFISEGGTNFSGGQRQRLAMLRLFMKEYPILILDEPTN"
     CDS             15016..15921
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 190; E-value:
                     8.4e-58)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_5941"
                     /transl_table=11
                     /translation="MKLAIQTKNLTKSFDNQSIVRDLNLSVPEGSLYAFIGPNGAGKTT
                     TMRMLLGLIPLDKGTILFNDKDIKEWKEELFENVGCFIDSPTYYPNLTAYENLAYVQKM
                     INKPLDEIDRVLKTTGIYKAKDKKVKDFSLGMKQRLGISFAILNDPKILILDEPTNGLD
                     PEGVHEIRRLLLHLVKNEGKTIFISSHNLAEIEMIADHIALLHNGNLLYEGNLNSIITS
                     REYIVHVNDTTATERILNTEGIPYSIEKEEIFKLIIDQNSVPNLTRILIKNDIDIFEVS
                     PKKLTLEEVFLSLTKQKELL"
     PFAM_domain     15076..15495
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_5941_0513"
                     /evalue="7.60E-30"
                     /label="ctg1_5941"
                     /locus_tag="ctg1_5941"
                     /protein_end="160"
                     /protein_start="20"
                     /score="104.3"
                     /tool="antismash"
                     /translation="RDLNLSVPEGSLYAFIGPNGAGKTTTMRMLLGLIPLDKGTILFND
                     KDIKEWKEELFENVGCFIDSPTYYPNLTAYENLAYVQKMINKPLDEIDRVLKTTGIYKA
                     KDKKVKDFSLGMKQRLGISFAILNDPKILILDEPTN"
     CDS             15924..16649
                     /locus_tag="ctg1_5942"
                     /transl_table=11
                     /translation="MQFIFKSVNSEMRKIGGRKLLLFSLFFSLLSSFLCISYFIFNKNN
                     PDMFQSTNLIAITVNFNTLTLSIFSACMWYFIISSENKYGTWAIIYTKPISKFKLLVAK
                     NLLFILFYLIFNILNFSVMGMYIFINGYEISILYFLKMLLLCTILSLAIPYSQLLFHLI
                     IKKGILAASLSVIWIFFSVTYGLFPAVFTKTFPIFYALNIVSDVMMKETTILLYLASSS
                     IYILGIMLLTVSFKYYTYE"
     PFAM_domain     15948..16463
                     /aSDomain="ABC2_membrane_4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12730.9"
                     /description="ABC-2 family transporter protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_5942_0514"
                     /evalue="3.10E-09"
                     /label="ctg1_5942"
                     /locus_tag="ctg1_5942"
                     /protein_end="180"
                     /protein_start="8"
                     /score="37.2"
                     /tool="antismash"
                     /translation="NSEMRKIGGRKLLLFSLFFSLLSSFLCISYFIFNKNNPDMFQSTN
                     LIAITVNFNTLTLSIFSACMWYFIISSENKYGTWAIIYTKPISKFKLLVAKNLLFILFY
                     LIFNILNFSVMGMYIFINGYEISILYFLKMLLLCTILSLAIPYSQLLFHLIIKKGILAA
                     SLSVIWIFF"
     CDS             16665..17363
                     /locus_tag="ctg1_5943"
                     /transl_table=11
                     /translation="VGILGEYKKSLHNGLYILLLLFMLIPISFQILLTVSSQSKDGVFM
                     HIAILSLFCRLFLPIAIGLLVSFSFVNEFRRKGYMSAIYHGVTLKTILSNKFLFCLIIT
                     FCYLICALVITSIPIVLTVDSLGTVYQKLILSVLFMVISSLIIVNLHFLINIIFYKIPL
                     LSLLVGVIGGLGSFFISHTNYWILFPWSYPIMSLYIDSIEPKQLYIILIVYVLSLIGCI
                     FIIKKSMRWN"
     CDS             complement(17709..18242)
                     /locus_tag="ctg1_5944"
                     /transl_table=11
                     /translation="MMYLVGSLLISLSMFSTTSFAATEGAVKSVTNSSYTGIAADINLL
                     KSVVVKDGYVNWHLGIGASKVEGGISKTPSGYKVFLNSGYNESGQNSKYWNTQYDTSIK
                     DGDRVNLKIINNGNGTVTMYVNGISSPVYGSFSQYEPVKMVQGVEDTGRNSFSQASFSN
                     VLLRADTSGSSYKS"
     CDS             18584..18742
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_5945"
                     /transl_table=11
                     /translation="MEKTRSKLNNATIEGSIETLKDENECLRMEINYLKKLKALLQKEK
                     KLQNKTK"
     CDS_motif       18584..18631
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MEKTRSKLNNATIEGS"
                     /locus_tag="ctg1_5945_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       18632..18742
                     /prepeptide="core"
                     /locus_tag="ctg1_5945_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-3.00"
                     /molecular_weight="4340.2"
                     /monoisotopic_mass="4337.5"
                     /core_sequence="IETLKDENECLRMEINYLKKLKALLQKEKKLQNKTK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MEKTRSKLNNATIEGS"
                     /leader_location="[18583:18631](+)"
                     /alternative_weights="4358.2"
     CDS             complement(18900..19058)
                     /locus_tag="ctg1_5946"
                     /transl_table=11
                     /translation="MKKIKKIVLSMVVISALACGMNSLLSPQQSSSNGGDTPSPTIPSV
                     SAEVSID"
     aSDomain        complement(18987..19058)
                     /aSDomain="TIGR04429"
                     /aSTool="tigrfam"
                     /description="Phr_nterm: Phr family secreted Rap
                     phosphatase inhibitor"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_5946_0101"
                     /evalue="7.20E-09"
                     /identifier="TIGR04429"
                     /label="ctg1_5946"
                     /locus_tag="ctg1_5946"
                     /protein_end="24"
                     /protein_start="0"
                     /score="33.7"
                     /tool="antismash"
                     /translation="MKKIKKIVLSMVVISALACGMNSL"
     CDS             complement(19058..20158)
                     /locus_tag="ctg1_5947"
                     /transl_table=11
                     /translation="MTVQEKSNKQLMELLNEWYEKIRLYHVKEAKQTYLQVKESLKVIE
                     TDPYLSFYYSLLDFRYKVLVDGVSITKDSFKNIEKFPNIEEDFLFLAYYYHFFKAIHFT
                     IIANYTEAKTHYEKAERLLIDIPDEIEQAEFEYRFSTYCYQSYQPFEAIQHVVKAKKIY
                     LNHVGYEINTALCDNVYGLACIDLREFEKAEECLNTVIDVFNKHNEEHLLLRARYNLGW
                     LYNIQDLYPLAIRQSSEIINKIPNHFKALFVLARAYYKLEGIETAKAYIKQGINYTNEA
                     GNEEYKHRFAVLNELFTELPRIKLEKVVTDAISYFEKEEMWDCVKEYAEILATQFYETD
                     NHVKASKYFYISSNAGKKHLKKGALK"
     PFAM_domain     complement(19961..20140)
                     /aSDomain="RapH_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF18801.3"
                     /description="response regulator aspartate phosphatase H, N
                     terminal"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_5947_0515"
                     /evalue="1.80E-14"
                     /label="ctg1_5947"
                     /locus_tag="ctg1_5947"
                     /protein_end="66"
                     /protein_start="6"
                     /score="53.6"
                     /tool="antismash"
                     /translation="SNKQLMELLNEWYEKIRLYHVKEAKQTYLQVKESLKVIETDPYLS
                     FYYSLLDFRYKVLVD"
     CDS             complement(21175..21483)
                     /locus_tag="ctg1_5948"
                     /transl_table=11
                     /translation="MVKWTPFAAMPEQFAGIREMVKEKNKVARPILTSAEKELVENLLL
                     CSLLSEEEILITYYEDGYLLTNYMTVIDIDSLNSAVICTDAFYNKMKLQFYNIVNVK"
     PFAM_domain     complement(21178..21459)
                     /aSDomain="YolD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08863.12"
                     /description="YolD-like protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_5948_0516"
                     /evalue="5.80E-25"
                     /label="ctg1_5948"
                     /locus_tag="ctg1_5948"
                     /protein_end="102"
                     /protein_start="8"
                     /score="87.3"
                     /tool="antismash"
                     /translation="AMPEQFAGIREMVKEKNKVARPILTSAEKELVENLLLCSLLSEEE
                     ILITYYEDGYLLTNYMTVIDIDSLNSAVICTDAFYNKMKLQFYNIVNVK"
     CDS             21780..22568
                     /locus_tag="ctg1_5949"
                     /transl_table=11
                     /translation="MKNNIKGLIEYGERIPHFHKDFPIILFWSHRSGCTSLANWFFFQI
                     GLYEEAMKYAPFIHYYESEIYKNKVDYYTNLEMQLLELSKDTIKLVRNPYKRAVSSFLI
                     LYDNPYASKQWEQIREYFYNDKNESKGISFKQFLYYVKEIGAKSILLDQHFSQQYIEGE
                     EKVIKQNIKLENFNTIIPQLEKEYGLLSSDISLLTNSNHHRAHQMIHKGNYADDDITNP
                     HFPSLPTYRSFYDEEALNLVSEIFTDDFEAYGYKKNEINF"
     PFAM_domain     22029..22547
                     /aSDomain="Sulfotransfer_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03567.16"
                     /description="Sulfotransferase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_5949_0517"
                     /evalue="1.50E-05"
                     /label="ctg1_5949"
                     /locus_tag="ctg1_5949"
                     /protein_end="256"
                     /protein_start="83"
                     /score="25.4"
                     /tool="antismash"
                     /translation="SKDTIKLVRNPYKRAVSSFLILYDNPYASKQWEQIREYFYNDKNE
                     SKGISFKQFLYYVKEIGAKSILLDQHFSQQYIEGEEKVIKQNIKLENFNTIIPQLEKEY
                     GLLSSDISLLTNSNHHRAHQMIHKGNYADDDITNPHFPSLPTYRSFYDEEALNLVSEIF
                     TDDFEAYGYK"
ORIGIN
        1 aggttactag atgtactaaa taatgcagtg agaattttaa gtaataaaaa cgagagaata
       61 aaaaggagat gttcagtaat ggagattaga aaaaaattag tggattcaag taaatatgct
      121 ataaaatgtc ccaatgcaat gaagccagaa ttcatcacag tacataatac gtacaatgat
      181 gcatcagctg aaaatgaaat ttcttatatg attggaaata ataatgcagt ttcgttccat
      241 gttgcagtag atgacaaaga agcagtacaa ggtattccgt ttgatcgtaa tgcttggcat
      301 gctggtgatg gtaacggaaa tggtaatcgt aaatccatcg gagtggaaat ttgctattct
      361 ttaagcggtg gggatagata ttataaggcg gaagataatg cagcaattgt tatagctcag
      421 ttaatgaaac aattcaacat tccaattagt aatgtacgta cacataaatc gtggagtggg
      481 aaacattgtc cacaccgtat gcttgacgag ggaagattgg atcaattcat tgagaaggta
      541 aataaagcat ttaacaacaa taataataaa ccaatacagc cagtaggtct ggggattgct
      601 gtaaataaat atccgaataa tggagggatt aatctatata gccaaccgca aggaggatat
      661 tttacgaggg tgatttatga taaaacaccg tatcttatta tagatgcagc gtggtatgaa
      721 aatcctatga tttgtctcgg aaacgaggca tgggctgctc tggaacattt cgatgtgcaa
      781 tggttcagtg cttattcaaa atatccacca ggtggcggta ttaacacgta tgatggtcct
      841 aacgggaatt atacaggctt tgtagacggg tctgttccat atagaatttt ggcacgaaaa
      901 gatggttatt tggcgattgg aaataatgca tgggtaaaag aagaacattt tgatgtgaga
      961 taaggttaaa gaattagagt cactcgtatg agtggctatt taatttttgg attggaatat
     1021 gattggaaat agaaaatgtc agtagtgttc tatactaagt tgtttttatg tttcgattca
     1081 agaataaaag gagtagttta gtgcgtaatt tgtttatgtt gaattaaata agaagtagga
     1141 aagaggtggt aaaatggata gtttacaaga ggtgaagggt gatgttcagg aaataaggca
     1201 agatattaag gaaatacgat tagagattag aagtttagaa atgcggacga caggtaatga
     1261 aaaggacatt attaatatta ataagcaatt agacaaaatc agtgctaata caacttggat
     1321 cctacgcctt attattggtg gactaattgg agctgctctt accttctttt tgaaaggagg
     1381 aggtatgtaa tgattgaaat tacagcaatg attggggttg ttgtagggat ttcacaaatt
     1441 gcaaaaacaa ctggactgca aacaaaatat attccgttat ttaatttaac acttggcatt
     1501 acgctaggtg ttttattttt gtctcaagat attaaaatga atctatttca aggaatgatt
     1561 atcggattgt cagctagtgg attatttgac catacaaaaa ttataaaaag ggatgccgat
     1621 agaaaatgaa aaagaaatac aagcatattt tatccatagt tgttgctatt attttagtag
     1681 tatcaattgg aacaaacgca cttgctgata gaacgctact tattcctgat ttaccaaaac
     1741 aaccataccg ttatggtgtt ggagcttatg aaggtgttgt ggcacattct acagctaccc
     1801 cagaggcgcc agcaattaat attcaaaaat atgagtctcg cacatggcgt tcagcgtttg
     1861 ttcactacgc agtggattgg aatgaaaaaa ttcaaattgc atctacaaaa catcaggcat
     1921 ggggggcagg tccagcagca aatgctagat ttgttcatgt ggaattgtgt gagacaagtg
     1981 atccattgaa atttaaacgt tcatatgaaa aatatataga attaattgcg gaaatcttgc
     2041 gagaacgaaa tattcatccc tctaaaggat tatggacaca tagggatatt acttataaat
     2101 taggtggaac agaccatgaa gatccactgg cttatcttcg tagtcatggc gtatctgagg
     2161 ctaagttccg agcagacgtg ttaaaggttt ataacgggag cacggttaca gtggatacca
     2221 aaccacaaaa accaaatgaa atatctggta cagtagagtc gaatggtatt gcatatattg
     2281 aaggatacaa tgtaaatctc cgctctggac catcaacaga aaatagtgtt attcgtaagc
     2341 tacaaaaagg tgaggcttat aaagtatgga ataaattagg gaactggtta cattttggtg
     2401 gtaaccaatg gatttattat aattcttcat atattcgttg ccaaggcaat gaacctgcta
     2461 cagtaattgg taaaagagtt atttcaaaag taaataattt acgtttctat gattctccat
     2521 cttggcagga taaagatgtt gccggtactg tagatatggg tttaggattc attattgata
     2581 caaaggtaat tgtaaataat tcaccacaat atagagtgca caatagtaaa ggtaaaacat
     2641 attatgtaac agcaaacgaa gcctatgtgt atgtgaagtg aaagagagga tctgctctac
     2701 tatggggcga tcctcttttt tttatttatt atgtataaat taggtttaat ggtgaaaaga
     2761 ggagtctatg aatgattttt aatttggaaa aatattcttg atagaaaaat gatatagtgt
     2821 tatattttaa tttaataatg tatttttcaa aatgggtttt tgacatgcta tagatttact
     2881 tcaagatgcc gattttgtga aaacagaagg taaggtatta gataaagaga catagtgttt
     2941 ataatgggtg ttaatcctgt attataattt aggagaaata tatcaagtaa ggagtttttt
     3001 tatgccgaaa tgggcaaagc ggattgccat gtttatgatt tttatctgta gtattttaac
     3061 tatcgacgct cttgttggta gcaaaaaagg tataaaagcc attacagcag cagttgagga
     3121 attaaccgca gatgaaaaaa atataggaaa tcaaaaagaa gtaaagcaag gagccgaaac
     3181 aagtgattat aaacatttag acaagcagca ttatgcatgg gtaatggatg attatttaaa
     3241 ggacctatct gatgtggcga accgatttag cattttagag gctgatgcag aaattaaggg
     3301 tactataaac aaatcatggg tttcagatgt aggcgatgtt ttctataaaa tgtcttatct
     3361 catctcaagt gtacgatatg tagaaccccc aacagaatta aagggtctac attcatctat
     3421 tttaaaggcg atggataact tgcaatttgt tatagacaac tatggagatg ctgcgagcca
     3481 aacagattta gcgaaattag gcaaatgttt aaaatcgtta agaagtgcta gggatacaat
     3541 agacgaggtc cgtagtgaat tatccactta tgaataatta tcataaaaac cgattagtat
     3601 tacagaacat cctcaaaagt atatatgaag tttagcgttt tctttgcggt taaggaaaca
     3661 gtaatctcaa aggtttcaat tctaatgctt ggtacatgaa agaggataac aagcaaggaa
     3721 tggaaggcag ggaagatcaa agctgttgag ttcatggaca aggctggcat gaagaaagtg
     3781 atattttaaa agaaaatgag gggatacgag gaaataaaat cattaaaatg atataaatag
     3841 attttatact tttagtattt gacaatgcaa ccacagtcat tagagaggat atagtagtct
     3901 gtgtaataac aaaaccaaaa cttacgttaa gtattagcgg acttgaacta ctcaccactt
     3961 aacgtcctaa cggacgtttg aagtgggaga ttcctgcgaa caccgatgta tccaccagtt
     4021 atcttagcag gctctacccg cagtccctac ggtgagaaca taagtatctt gtacgctgac
     4081 tcaccacact atctacttta gcttggtttt cgcaattttg agaagcgtgg ggtgatagaa
     4141 cgttgaagat tttacggttg caacgttttt ctgcaaccaa cctcatatct tcagttttcg
     4201 aagagcaatc tgtacaagta aatgataaca aatatgttgg cttatgccaa ccgacattca
     4261 tcttccacct aaaattggtg tttcacacct tcacattttt gaggaaggag tcttctgtcg
     4321 gaaaacgata aaagactgat tttgaatgtt atgatgtcca ctaatgctta tagcgtgatt
     4381 tggttctagt gctatacaaa ggccatcatc accatactga ataaagtgaa taaaatatag
     4441 atttgattta taagtcggag gagggcacct tagggtgtct tttcttttat ccattacacc
     4501 cattgtttac acattgattt tttatcattt tagccaagaa gactccttcc tcaaggagcg
     4561 tgaagggtca cagcccagtg agtaggtggg agatgaattg gcttcgaaca agggatggca
     4621 ggaagccatc ttaattgttc gacatacaga aagtgttact cgactnnnnn nnnnnnnnnn
     4681 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4741 nnnnnnnnnn nnnnnnnnnn nnnnnttggt tccaagaagg agatgcttgg tactacctgg
     4801 atgctaatca agggggctcc atggtaactg gacaagctac tatagaagga aagacttata
     4861 catttgctgc ggatggtaaa tggtccgagt cggaatcttc aggtatcatt gatttagcat
     4921 taaaacaatt aggcaaacca tatgtatttg gaaactctgg tccaaattcc tttgactgca
     4981 gtggttttat ctattatgta ttcaaaaaca atggatacaa tattggaaga acaagcgttg
     5041 cgggatactg gggaatggtt actaaaataa gtaatcctca gccaggtgat ttagtattct
     5101 tgcaaaacac atataaggcc ggtccatcac atatgggaat ttacttaggt aatggcgagt
     5161 ttattcatgc tgcggacgaa agaacaggtg taacaaaagg taatgtaaat agtcaatata
     5221 atagagagca tttccttgga tatggtagat ttacaaaata atgaattatc tctagaaaaa
     5281 cgccttcaaa tttgaaggcg tttttctctg ttacatagca actacacaat aaaagtggaa
     5341 tttaataaag taaacataaa ttgaatatta ctgtggtatc tatcctttga taaagtactc
     5401 tttttgatac tgtaaagaat aaaatatcag tttgaaagaa tggtccatca tattcttcaa
     5461 ataattgttt gtttactttt cctaaataaa tttcttcatt taaaagaagt taatattatg
     5521 gtttgtatac cttcaattgt gcatcaaaaa gctagtccga aagtatataa aacaccccac
     5581 catccacatt ttattaaagg tggtaatatt gaaatatgga aaatagcttt agccacatct
     5641 gccgcaccga cttatctatc tgcagcggtt atagatgata atgaatgtaa aattgacggg
     5701 ggattatggg caaataatcc tgtattggtt gccattgctg aagctgttaa gttgggctat
     5761 tcattggagc aaattaaagt tctctctatt ggaactggaa caagtttatc attttagcca
     5821 agaagactcc ttcctcaagg agcgtgaagg gtcacagccc agtgagtagg tgggagatga
     5881 attggcttcg aacaagggat ggcaggaagc catcccttgt tcgacataca gaaagtgtta
     5941 ctcgattnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     6001 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnact gtccttcttg
     6061 tcgtacacac catgataggg atattaacgc aagtatcaat ctaaagaatg aagcgataag
     6121 gcttctaacc gcaaggactg cggggatagc ctaacaaatt agagttcgat agaactcttt
     6181 acttaggaat ccctcacttc taaacgaagt gaaagtgggg gtagttcaat aacgcgttta
     6241 aataaggtga aagaactttt aaatactatt cctaatgcat actggacaaa tcaatataat
     6301 aatgccgata actttgaagc tcattatcaa ggaattggtg gagaaatatc taatgatttt
     6361 aaacagttag attatgcctt cattggagtg agtactggag ggacgatcgc tggggtatct
     6421 acacgattaa aagaaaaatt ccctaatatt aaaattattg cggtagatag tcaaggatcc
     6481 attatttttg gtgataagcc tcgtaaacga tatataccag aaattggtgc cagtatgata
     6541 actggtatgg ttaaaaaagc attgattgat gatgtaatga ttgtaccgga ggttcatact
     6601 gtttcaggtt gttatgagct atttaataaa catgaaatat ttgccggtgg atcatcaggg
     6661 acttcatatt atgcaatcca aaagtatttt gaaaataggg atgttcaaaa tacccctaat
     6721 gttgttttct tatgtcctga taatggtcaa gcttacacat ctactattta caatgtagaa
     6781 tgggtagaat ggcttaatac acaaaaatca gtagaagatc aattagtttc tttataaaaa
     6841 tgatatagaa atgaggaagc aattatgatg tatttaaata ctaaacatat taatgaaatg
     6901 ggtgttaatt gggaagaaac aataaatgcc atttcaaagg cagtaaaaag tcttgattca
     6961 gaagattttt ctcagccaat taagccatac ttacgtttcg atgatccggc taatagaatt
     7021 attgctatgc cagcttatat tggaggagaa tttaaggttt caggaatcaa atggatagct
     7081 agttttccga agaatattga gaaaggtatt caacgtgctc attcagttac tatattaaat
     7141 gatgctatga ctggaaaacc atttgcgaca cttaatacag caatggtcag tgtaatacga
     7201 acagcttctg ttacagggtt aatgattcga gagtttgcca agttaagaga tttaaataat
     7261 gttaaagttg gaattattgg atttggacct attggtcaga tgcatttaaa gatggtaact
     7321 gccctattgg gcgataaaat cgaaagtgtt tacttatatg atatcaatgg aattaaagac
     7381 gaattaattc ctgaggaaat ttattctaaa actcaaaagg ttaatgcata tgaagaagcc
     7441 tataatgatg ctgatatttt tattacttgt actgtttctg cagaaggtta tattgataag
     7501 aaacctaaag atggggcgct actactcaat gtttctcttc gtgattttaa gcctgatatc
     7561 ttagaatata caaaatccct agttgttgat aattgggaag aagtctgtcg tgaaaaaact
     7621 gatgttgaaa ggatgcacct tgaaagaggt ttacaaaaag aagatacagt atcaattgct
     7681 gacgttgtaa tccgaggagc actgcaaaac ttcccttatg acaaagcaat attatttaat
     7741 ccaatgggta tggccatatt tgatgtagcc attgctgctt attactatca aagggctagg
     7801 gaaaatgaaa tgggtgtttt attagaagac tagtaaaatt attaaaacgc agtttgaaat
     7861 aattgtctaa tagctgttaa atatcggtaa acaagactaa tcattataga aaattagtta
     7921 tttgataagc ttagaattta tgtaattatt tgaggagctg tttttatgag tgaaattatt
     7981 tcggccttag atctcttaca tcccaagcaa attcgctttc atgaatcata tgaacacaaa
     8041 agattggaac aaatttgtcg tgtaatggaa agagaaggtg ttttacggaa tcctccctta
     8101 gtatctgagc ttagtgatgg taattatctg ttacttgatg gtgcccatcg tatgaaggct
     8161 atgatggcat taggttgtaa acgcgttgct gtacaggtag tacctgatga aaaaataaaa
     8221 attcgtgctt ggaatcattt attaccaatg ggggaatggg taaataattt aaagaaagaa
     8281 cctacaataa tttggtcagg taagattatt gctaataaac gtttgcttgc aaaaattaca
     8341 gaagcaaata aacaagaaca ttttttatat gcaagggatt taaatagcga tttatttaac
     8401 catttagaga tatggcatcg tattgtcggc ttatatcaac atgagtatac ggtacgccgt
     8461 cattcaaatg atactgaggt ctggcctcat tcaaatgaaa tattgatgag ttatccagaa
     8521 tactcgttga tggaactgaa aaaggtaatt gaagcaaagt ttttaatgcc agcgggagtt
     8581 actcgtacga cgcttagtgg tcggttattg aatttacgta taccacttca tatattgcgt
     8641 acggaagtat atcctgctgg tgaatgggaa acgttatgtg gaaattggtc aaaatgttta
     8701 cgcctttatg acgagccaat atatgtttat gatgcataat atgttgttta gtgattataa
     8761 tgtatatttt ttatttattt gtaaaaattt cattatatga tttatattaa ttccaaaata
     8821 tttttattat gttataaaaa ctgtttgaat tagtatttaa gactaatcta agagaggttt
     8881 gttatcgaat gggggtaaat attacaaaaa aggacaaagt ggagatttct aaaaaattaa
     8941 aagttttttt ggctgatcaa tattcacttg aattaggcga ttacataagc tttgagatac
     9001 ttgaatttat aataaaggaa ctaaatccac attttaatca agctacaaag aatagattgg
     9061 aaattctgtt aaagaatata gagaaagaga tatatagtga attagtttca cacggaaata
     9121 acaaagcata gaggttattg tatgtgttta aatgtagaat agtttgaact tataactaaa
     9181 taatgtgttg ctattaattt ggtagaatag tgaggaacaa gagaattggt aatatacaat
     9241 ttttagaaga gatgaaattg agaagtgaat atacttacaa tttcatcttt ttatttttaa
     9301 aacgcttttt gtaattcaag cttaatacta gatctttaca gaatctttag gcagggtgaa
     9361 ttttgtaaga gaaattaaat attttaaagt tatttcatga ttaaaatttt tggttgaaga
     9421 cttataaaat taaagaaaaa gagtgggtta tcccttttta tggtaaaata ttctttagtt
     9481 atatcttcta taatctaatt tttttcataa gtgtaattac aattcttaat cgttagttag
     9541 aaaaatagtg ttcaaatttt aaagatataa taagtaagtc tcttttaatt atattaatat
     9601 aattaaatat cctattattt tatttttttg taaatatatc tttttttcat taacatttaa
     9661 tggtatattg ttcatagaca atgttgtggt aaattattga atttataaca tcattttcaa
     9721 aaaatgaagg taggtattaa aatggataat gaaaaatatt tacaagtcgt agaagatgaa
     9781 gagcttgaac aattagttgg tggtattgga cctggttggg ttgaaacttt aactaaagat
     9841 tgtccttgga atatgcctgt agcatgcgtc acaattatgg gacaaagaat ttgtaaaaaa
     9901 tgccgctaat agttaaagag agtaaggcct ttcgccttac tctctttaat aataatgaat
     9961 ttctaactgt ttctcctacc tataaaaaga agaggttatt atgaaaaata attcacatgg
    10021 aattttgaat acaatagata atggggcttc tttagtaaca aaagaagacc tagaaaaaaa
    10081 ttttggtatc tttttagagg gtttttcatt taatgatatc attaagaatg acgaaaacta
    10141 taattttcaa aaaataatac aaacatatgt agtattctct aaaaatatga taaaaaataa
    10201 aattgatttt tttggtaatg ttgagaggat ttctgaatcg ataatgtttg atttagaaag
    10261 aaggctatac caagtattaa gaccatcctt aattgtatac ataaataaac ttagagtaga
    10321 aaacgttttg ataggaatgg atagcggtga agaatataag tattttacaa agaacttctt
    10381 tcattttaaa aggttctata taaatttttt taaaatatta cctttattaa atgaaaaaat
    10441 ttttaaaata attgaaaatg aaataaatta tatgatttgg ttacaaggaa ctcttgaaaa
    10501 agatcaaaaa gaaattcata aaatgtcaac ttttaatgtt atgcatgtgg aaaaagttac
    10561 taacctaggt gactatcata ataatggaaa gagaacaata cttttagaag ataaatttaa
    10621 taataaggta atcttaaaac cagttgattt gaaaaattct atcttatatc atagtttaat
    10681 taatcaactg aataaggatt taaatactaa tatctttatt ccgcaagtag ttaataagag
    10741 aaattatgga tatatggaat atattaatca tgaatcatgt gaatctactg agcaaattaa
    10801 agattattat tataatttag gtgtagtgct ttctgtaatg tatttgatta atggaagtga
    10861 catacataat gaaaacatca tagctaaaca atcctcacca gtcataattg attttgagac
    10921 attaggaagt acattaaatc caagtatcac tgaagaaaca agtagtttta tattatctaa
    10981 ttcagtatta aattctagaa tgctacctat aaagtttagt ggaggtagag aggtaataag
    11041 agattacagt gccattggga gagtaatgca gaatttggta aaaacaatta aaataaaaaa
    11101 tgaatttaca tcgaacccga ttgaaataaa agaagagaca atagtagaag atacagttca
    11161 gaatttaccg ttttttaacg gtgatatata cgagtatgat aattatataa aagatattat
    11221 taaaggtttt gaggatgcat ataatacagt cttaaaaaat aagaaggaat atgtgtatat
    11281 attgaaaaat agtgtttcta aatggaatta tcgaaaagta tatcgaaata caaaagttta
    11341 ttctctttta ttagatagac taaatgttcc agatctatta gagaataaat caaagactat
    11401 aaagtattta aaaaatatac ttgagaaaaa tatctacttg gctactagga aagatattat
    11461 tcaaaaagag atagaggcac tattatctta tgatgttcca tatttcttta ataagtatga
    11521 atgggggtct tacgagagtt tatcaagtaa tgaaatagat ttagaaatga aattcaaaaa
    11581 aatttcatat gctgactttt tattacaaag aaaaattata gaaatatccc tttctaatca
    11641 aaatgataat ctatataagc tgaatacagt aaaggaaaca attaattttc agactaattt
    11701 acctacaaat aaaataaggg aagcaattac agagaaaatt cttgatggtt gttatatatc
    11761 aaaaaacggt gatgtagatt ttattggatt aaaaacaaat tggcaagggg agctcgagat
    11821 aaaccatttg aataatggaa tatatgatgg ggtattggga ataagtacat tattgagaaa
    11881 taacgcagac cctaatcaca ttgaaattat aaataaactc gaacaaaaag ctttgcaaga
    11941 aatactaaac aggaataaaa ataattatgg ttttgtaaat ggtgttaatg ctatcatttc
    12001 ttattattta acaaattccc catataaaac ctatattgat gaaaaggtag tattgcaaat
    12061 atttatggat atcaactctg atattgaaaa aggtcgatat aacgataagc attttgatat
    12121 attagggggt tcagctggtt tagttttaac tgcagttaag ttctatcaag ttaatcctaa
    12181 gtataaaata ttgcttaaag ttgctgaaaa tctcggcgac tacattgtca ataatatgca
    12241 aacaaatgat gaatttttat attggaaagc tcacgatact ctaaatttag aagattcttt
    12301 aaagggattt gttcatggat tatcaggtca acttctcgca ctttataagt taaaagacat
    12361 attaaaaacc aataagtacg atagagtaat acatggtata cataaaagtg agaaagtgag
    12421 tatgagtgaa tatgagtata cagacagctg gtgtaaaggg tttagtggaa tgggaatatc
    12481 aagaattaaa attttagaat catatcaaaa tgaagatata caatcagatt taatcttttt
    12541 taaaaatcaa atcttaagta agttacatgt aaacagtgat tattgtttat gtcatggttt
    12601 aatggggaaa ctagactttt tattggagtt agaaaataga ggtatgttag agcaaaatga
    12661 aaaacaaatt gttatgaaag taacaaataa ctttttgaat aattttgata tagaagatta
    12721 taatcctcat aaaatcgcat tatttacagg tttaggaagt attttgtatt ttctgcaaag
    12781 gttagagaat aataaattaa atagcatttt atactttaat gcctagaata ggtgataaat
    12841 atgttaagaa agaaaattaa gtttataccg caaatgacgt cttttgattg tgggcctagt
    12901 tgtctagcga tggttatgca ttattatggt ttagcagtac aagcttcgga aattagaaat
    12961 agtaaaatta tcaataaaaa atcgtcatgg agtttgttgg atattaaaaa agttagtgaa
    13021 tcgtatggac tctctgcaac tgcatataga atagaaaata cagctgattt aaaatggata
    13081 caaaagccga tgatagcatt ttggggcttt aatcattttg taattattga aagggttaaa
    13141 gaaaataaat tttatattgt agatcctaag gcaggaccca tggtaattga tataagaagt
    13201 tttgaagaga tgttctgtaa ctatatctta gtaatagaaa acaaagaaga tatacagcca
    13261 gatattaaaa ggcgtgaaaa acatatacta cttagatata ttgatcattt tgtatcccct
    13321 agtcagatga tcttactagc actactaaca ttattagcac aaatctcaat ttttactttt
    13381 ccgtttattt tgaaaaagtt tatggatatt ttgaatgctt caaaggaagt ggatgtaaga
    13441 tacctattaa ttatattggg gagtttaata gttgttatag ggataaaatc tataacttca
    13501 attataaaag taagatttca aaaagagatt gatagaaaaa gtacaacaaa agtttttgag
    13561 catatgttta atattcccat agaaaagatt acttcacgtc atgcaggaga tttaaatgta
    13621 agaattatga gtctagagtc aatacgagga tatattttag aagatctaat tgaaatgatt
    13681 atatcaatag tagttatcat tccattattg atgtatctat tatatactga gactttttat
    13741 actttaatat tgatgttttt tattgctagt tccctattta tcaatatttc cttaggaaaa
    13801 tttatatata atgctaattt agtcgaaacg tattacctag gggaacatag aggtaaaatt
    13861 aatgaatcat taaaagcaat gtattatgta aaggccacag ggattttttc taaaattaaa
    13921 tctgtatgga aaaaagatta taataaatac ttagatacgg tgcataaacg agtgctaaaa
    13981 caaaatgctt tagaatcatt taatagttcc ctatcaacaa tatttattat cataatgctt
    14041 gcggtaggat tttataattt tagtaaagga gaaggggatt taagtaatat ttttttcttt
    14101 attgccatat ctagcattat attttctccg gtttcaacaa ttataggatc aattttaaat
    14161 tggaattcag ttaaaccaat tttattaaga actttagaca tcttggaaga ggagttggag
    14221 atagatagat cggatactaa agtaaacatt cttagaggct caattcaatt taataatatt
    14281 tcgtttagtt ttgatgacaa aaaaataata gaaaacttaa gtttgaacat taaaaataac
    14341 gaaagtattg ctattgttgg agaaagtggc agtgggaagt ctactttggc taatttatta
    14401 ttaaaattgc atactcccga taaggggaat atattaatag acaatagaga tattaaagat
    14461 tggaacagtg aggaactaag aaaaaaggta ggactaatga ctcaggatgg agttttattt
    14521 agaggtagtt tatctgagaa tttatcttac tttgatataa attatgatcc ttcaaaaatc
    14581 cagaatgcta tacttaaatt aaatctaagt aattatattc aatttcaaag tataaatgat
    14641 atttttatct ctgagggagg aacaaatttc tccggtggtc aaagacaaag attagctatg
    14701 ttacgtctgt ttatgaaaga atatccgatt cttatcttag atgaaccaac taaccattta
    14761 gatagggaaa cggcaaatac tgttattgaa aatatatttg ccatgccatc caccaagatt
    14821 attattactc atgatgaaaa tattttagag cgtgtagata aagtctatga acttactgat
    14881 aaaaaattag aacaacgaga aatattttct aaaccccaat tgcaaacatc aggtaaagga
    14941 tgaatagaat ttctaataaa tccataattt aatagatact tacttttatt tcgaaatgag
    15001 aaagtgagga acaaaatgaa attagcaatt caaacaaaaa atttaacaaa gtcttttgac
    15061 aatcaatcca ttgtaaggga tttaaactta tctgttcctg aaggaagttt atatgctttt
    15121 attggaccaa atggtgcagg gaaaacaaca acaatgcgaa tgttattagg attaattcca
    15181 ttagataaag gaacgatatt atttaatgat aaagatatca aagaatggaa agaagaatta
    15241 tttgaaaatg tggggtgttt tattgattca cctacctatt atcctaattt aacagcatat
    15301 gaaaatttag cctatgtaca aaaaatgatt aataaacctt tagatgaaat agatagagta
    15361 ttaaaaacta caggaatata taaagcaaaa gataaaaaag tgaaagattt ttctttagga
    15421 atgaaacaaa ggctaggtat ttcctttgct attcttaatg atcctaaaat actaattctt
    15481 gatgagccga caaatggatt agacccagag ggagtacacg agataaggcg gttattactt
    15541 catttagtaa aaaatgaggg taagacaata tttatttcta gtcataattt agctgaaatt
    15601 gaaatgatag cagatcacat agcattacta cataatggta acttactcta tgaagggaat
    15661 ttaaacagta ttattacttc tagagaatat attgttcatg ttaatgacac tactgccaca
    15721 gaaaggattt tgaatacaga gggtatacct tatagcatag aaaaagaaga gatattcaaa
    15781 cttataatag atcaaaatag tgttcctaat ttaaccagaa tattaattaa aaatgatata
    15841 gatatttttg aagttagccc taaaaagcta acattagagg aagtgttttt atctttaact
    15901 aaacaaaagg agttactata ataatgcaat ttatctttaa aagtgtgaat agtgagatga
    15961 ggaaaatcgg tgggagaaaa ttattattat tttctttgtt tttttcatta ttatcaagct
    16021 ttttgtgtat aagttatttt atttttaaca agaataaccc tgacatgttt caatctacaa
    16081 atcttatagc aattacagta aactttaata cactaacgtt aagcattttt tctgcttgta
    16141 tgtggtattt tatcatttct tctgaaaata aatatggcac ttgggccatt atttatacaa
    16201 agccaatttc aaagtttaaa ttattggtag ctaaaaattt attgtttata ctgttctatt
    16261 taatctttaa tattttaaat ttttcagtta tgggtatgta tatttttata aatggatatg
    16321 aaatatctat actttatttt ttgaaaatgt tgttactttg tacaattcta tctttagcaa
    16381 taccatattc tcaattactt tttcatttaa ttataaaaaa gggaattctt gcggcgtctt
    16441 tgtcagttat ttggattttc tttagcgtaa catatggatt attccctgca gtattcacaa
    16501 agacatttcc aatattttat gcattgaata tagtaagtga cgtaatgatg aaagaaacaa
    16561 ctattttact atatcttgca agttcttcaa tctatatttt aggaattatg ttattaactg
    16621 tgagttttaa atattatact tatgaataat aaagggtgaa ataagtgggt atattaggtg
    16681 aatataaaaa aagtcttcat aatggattgt atatcctgtt actattgttt atgttaatac
    16741 caattagttt tcaaatcctt ctaactgtat catctcaatc aaaagatggc gttttcatgc
    16801 atatagcgat tctaagcctt ttttgtagat tatttttacc aattgccata ggtctattag
    16861 tatctttttc ttttgtaaat gaattcagaa gaaaaggata tatgtctgct atttatcatg
    16921 gagttacttt aaaaactata ttaagtaata agtttctgtt ttgtttaata attacttttt
    16981 gttatttaat atgtgcttta gtcataacta gtatacctat agtattaaca gttgatagtc
    17041 ttgggactgt ttatcaaaaa ttaattcttt ctgtactttt tatggtaatt agctctctaa
    17101 ttatagtgaa tctacatttt ttaataaata taatattcta taaaatcccc ttactttcat
    17161 tattagtagg agttataggc ggactgggta gtttttttat ctcccataca aactattgga
    17221 tactatttcc ttggtcatat ccaattatga gtctttatat cgatagcatt gaaccaaaac
    17281 agttatatat tattcttatt gtatatgtat tatcattaat aggttgtata tttattatta
    17341 aaaaatcaat gcgatggaat taaagttaaa ataagaagag tagtattatt aaaaatagag
    17401 cgtgttgtag ttgctagaag ctgaaactcg atacgttaag tggagtaata agacatgctg
    17461 atcaagtact attgaattca aagaagctaa aatatgaaga atgcaattta tggctgatag
    17521 aatatctatt aaaaattatc catatgaaaa aggtagctgt acaaaagtac agctaccttt
    17581 tttcacaaaa acatccgtat acaagaacaa tcttagcgta aacttgcgct taatggtact
    17641 tgagaataaa ctgtgaaact gttaccataa gtaccgtgtt tagaaaatga ggaagaaatt
    17701 gaaccgtttc aacttttgta ggaagatcca gatgtatctg ctcttagaag tacgtttgaa
    17761 aagctagctt ggctaaaaga attacgtcca gtatcttcaa cgccctgaac catctttact
    17821 ggttcatatt gagaaaatga gccatataca ggactagaaa ttccatttac atacatagta
    17881 accgtaccat tcccgttatt aattatttta aggtttactc gatcaccatc tttaattgat
    17941 gtatcatatt gtgtgttcca atacttactg ttttgacctg attcattata tcctgaatta
    18001 agaaatactt tatatccact tggtgttttt gaaataccac cctcaacttt agatgctcca
    18061 atacctaaat gccaattcac atatccatct ttaacaacaa ctgattttag tagatttata
    18121 tcagctgcaa tcccagtata actactattt gtaacacttt ttacagcacc ttctgtagct
    18181 gcaaaacttg tagttgaaaa cattgataga gaaattagaa gtgaaccgac tagatacatc
    18241 atttttttct tacttttcct taatacttga ttcattttta attattaaat tgtattgaaa
    18301 gttggccaac taactacgac ttacaaacca aagatacatt aggtttaatt taatgtatat
    18361 attttcctgt cataagtcat tgaaatgtca aataaattag atgtttcata tttatcaata
    18421 taggggattt ttcaaaagat atatctcaaa ttctgagaaa taaaataaaa acaaatgaat
    18481 tgtttgtgtt aaagaattta ttgcaatagt tcgtaggtga agggaaatat atgctttaaa
    18541 aggcgtggaa ttcctatata aaaagaagaa aggggggcca gctatggaaa agacaagatc
    18601 aaagttaaat aatgcaacta ttgaagggag tatagagaca ttaaaagatg aaaatgaatg
    18661 tttacgtatg gaaatcaatt atttaaaaaa gttaaaggcc ttacttcaaa aagagaagaa
    18721 attacagaac aagactaagt gaaagttcta gtctaccatt ctacgtacaa ttatagtaac
    18781 aagaatagtc cgaaacaaat ctgtttcgga ctaggggttc aatattttat ccattgtatt
    18841 ctacattttt tataaaaagt tgaattttct gattttaaat ccaagaaaaa tgtattacgt
    18901 taatcaatag atacttctgc agagacacta ggtattgttg gtgatggtgt atctccacca
    18961 ttagaagaag attgttgagg tgaaagtaaa ctattcatgc cacatgctaa tgcacttatt
    19021 actaccatac ttagtacaat cttttttatt tttttcatca ctttaacgct ccttttttca
    19081 aatgtttctt accagcatta ctgctaatgt agaaatattt gctcgcctta acatggttat
    19141 ctgtctcata aaattgagtt gctaaaatct ctgcatattc ttttacacaa tcccacattt
    19201 cttctttttc aaaataagaa attgcatcag tcactacttt ttctagttta attctaggta
    19261 attctgtgaa tagttcattt aaaactgcga aacggtgctt atattcctca tttcctgctt
    19321 cgttcgtata gtttattcct tgcttgatat atgctttagc tgtttcaatg ccttctaatt
    19381 tataatatgc tcttgctaag acaaataatg ctttaaaatg attcggtatt ttatttataa
    19441 tttcagaact ctgtcggatc gccaatggat ataaatcttg aatattatat aaccagccta
    19501 aattgtaacg tgctcttaat aataaatgtt cctcattatg cttattaaaa acatcaataa
    19561 ccgtattgag acattcttcc gctttttcaa attctcttag atctatacag gctaaaccat
    19621 atacattgtc gcataaagca gtattaattt catatcctac atggttcaaa tatatttttt
    19681 tggcttttac tacatgttga atcgcttcaa atggttgata agattgataa cagtaagttg
    19741 aaaatctata ctcaaactcg gcctgttcta tttcatcagg tatatcaatt aaaagccttt
    19801 ccgccttttc ataatgtgtt ttcgcttcag tataatttgc tataattgta aagtggattg
    19861 ccttaaagaa atgataataa taagctagaa ataaaaaatc ctcttcgata ttagggaatt
    19921 tttctatatt cttaaaggaa tcttttgtaa tactcactcc atctaccaag actttatatc
    19981 taaaatctag tagtgagtaa taaaatgata aatatggatc agtttctatt acttttaagc
    20041 tttcctttac ttgtagatat gtttgttttg cttcttttac atgatataaa cgaatttttt
    20101 cataccattc atttaataat tccatcaatt gcttattact tttttcttga acagtcataa
    20161 tatccccctt ttctctgtaa aggcttaatc tgataataac aggaaataga tagtttttaa
    20221 ttaactacga tttttttcat gaataataag aatattctga aaaataaagg cgtacttatt
    20281 ttgttgatat attcaatttg ttttaaaaca gaccgtctgt aataggcggt ctgttgtttg
    20341 ttatgatcgg cgactgctat tcttttactc atctcatatt atannnnnnn nnnnnnnnnn
    20401 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    20461 nnnnnnnnnn nnnnnnnnnn nnngggatca caatggaagc gatttgagtt agcttcagca
    20521 ggtagtgcgt ctcctcatgg aagtataaca gctgtttcga gaatccctgg aagtatggaa
    20581 gtatggtgga ttggtgcaaa tggatcggta caagatgcat actggtatga gggatcacaa
    20641 tggaaacaat ttgagttagc cccagcaggt agcgcttcta tcggttaaat tatttaaaaa
    20701 agtaaaaaat gaaaaatatc tgaaggaaac tagatggggt cttcttatat ttttttcaga
    20761 ggatgatgaa gatggaacat ggaacatata aaacacatag atttactctt aaatgtaaag
    20821 catcagattt caactacatt cctttgttaa aagcaatctg taataaggat atgagaataa
    20881 gaccaagtat ttttcatatt caactaactg gggacttatc ttgaataaga tttatgcatt
    20941 gattttcaac actagggcgc tttctttgaa taaaccttag atttttaaac ggctttattg
    21001 ttatattttt tggtgtagtg aagtatctga catcaagatt aaaaaactat atttttaacc
    21061 ctgtcctaaa tttagaacag ggttatgctt gtttgaactt ttaaaattaa aaaactttat
    21121 tgtcatttta aagtcttctt atttaccata taatatagga ttcgtggaga ccttctattt
    21181 tacatttact atattataaa attgtagttt catcttgtta taaaaagcat cggtacatat
    21241 aacagcacta tttaatgaat ctatatcgat aacagtcata tagttagtaa gtaaataacc
    21301 atcttcataa tatgtaatta atatttcttc ttcagatagc aatgaacaca gtaacaagtt
    21361 ctcaaccagt tctttctctg cggaagttaa aatagggcgt gctactttat ttttctcttt
    21421 gaccatttca cgtattccgg caaattgttc tggcattgct gcgaatggtg tccatttgac
    21481 catcttatca agactttttt tcgattattg tagcgatatt aatgcctcta tcgttgtata
    21541 catatcttca tacataattc tctttataat agatttctat attttaaagt ttgttaagca
    21601 attattacat tttgataaac ctggaaaatt aagacaccta tgtaagctgt ttttaataca
    21661 ctgggatttt atatgccaac ttaagtacct ttacagtggt gtttaaatac aatggtatga
    21721 gtagttacca ttgtatttaa gtgttcaata aatatcagaa taacgaaggg gtttggctga
    21781 tgaagaacaa tattaaagga ttaattgaat atggcgaacg tattccacat tttcataaag
    21841 atttccccat aattttattt tggagtcaca gaagtggttg tacttctctg gcgaattggt
    21901 ttttcttcca aattgggtta tatgaggaag caatgaaata tgcaccgttc attcattact
    21961 atgaatctga aatatacaaa aataaagttg attactacac aaatttagaa atgcaactct
    22021 tggaactaag taaggatacc ataaaacttg tgcgcaaccc ttataaaaga gctgtaagct
    22081 catttttaat actttatgac aacccttacg cctcgaaaca atgggaacag attagagagt
    22141 atttttataa tgataaaaat gaatcgaaag gaatttcatt taaacaattt ttatattatg
    22201 taaaagaaat aggggctaaa tccattctgt tagatcaaca tttttcacaa caatatattg
    22261 agggagaaga aaaggtcatc aaacaaaata taaaactaga gaattttaat acaataattc
    22321 cgcagctgga gaaagaatat ggattacttt cttctgatat atcactcctt acaaactcca
    22381 atcaccatag ggcacatcaa atgattcata aaggaaatta tgcagatgat gatattacaa
    22441 atccacactt cccttcatta ccaacctatc gaagttttta tgatgaagaa gctctaaacc
    22501 ttgtttcaga aatatttact gacgattttg aagcatatgg atataagaag aatgaaatta
    22561 atttttaact aatataccta tcacccgact atgtatagag tctctttaaa aactataacc
    22621 actatgaaaa gccagcggta tggaagggga attataatga gcatttctat tataatgatg
    22681 ggtttcatca tagggggatt ggttggagta acagggatag gcggggccgc attactgact
    22741 ccatttcttc taacattagg cataagtcct tctgtagctg ttggaacgga tctagtatat
    22801 aattctatca ctaaaatgtt tggaat
//
