LOCUS       NC_000964.3            20270 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_000964.3 Bacillus subtilis subsp. subtilis str. 168 complete
            genome.
ACCESSION   NC_000964
VERSION     NC_000964.3
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 16:07:02
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 4088149
            Orig. end    :: 4108419
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..20270
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[4098149:4098419](+)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10270
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..20270
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..20270
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="13"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(1280..3160)
                     /locus_tag="ctg1_4096"
                     /transl_table=11
                     /translation="VAKKEFKAESKRLLDMMINSIYTQKEIFLRELISNSSDAIDKIYY
                     KALTDDALTFDKDSYYIKVAADKDARTLTISDTGIGMTKDELEQHLGTIAKSGSLAFKK
                     ENELKDGHDIIGQFGVGFYAAFMVADVVTVISKALGSEEAYKWESAGADGYTIEPCEKD
                     SVGTDIILKIKENTEDDSYDEFLEEYRLKAIIKKYSDFIRYPIKMDTTINKPKEGSENE
                     FEEVQEEQTVNSMVPIWRKNKSELTDEDYEKFYAEKHYGFDKPLTHVHISVDGAVRYNA
                     ILFVPENMPFDYYSKEYEKGLELYSNGVLIMNKCADLLPDHFSFVKGMVDSEDLSLNIS
                     REMLQHDRQLKLIAKNISKKIKSELQSLLKKDREKYETFYKSFGRQLKFGVYNDFGANK
                     DQLKDLLLFYSSKEKKLVSLDEYVSRMPEEQKFIYYATGDSYDRIEKLPQTEMVADKGY
                     EILYFTEDIDEFAIKMLASYQEKEFKSVSSGDLGIDTDEDQKQSEEEESKYKDLFEEMK
                     NILSDKVKNVRISKRLKSHPVCLAADGEVTIEMEKILNAMPDSQNVKAEKVLEINPNHE
                     VFQTLQDAFEQDKEKLSLYTNLLYNQALLIEGLPIQDPVEFTNNICKVMV"
     PFAM_domain     complement(1286..2512)
                     /aSDomain="HSP90"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00183.20"
                     /description="Hsp90 protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4096_0608"
                     /evalue="1.20E-113"
                     /label="ctg1_4096"
                     /locus_tag="ctg1_4096"
                     /protein_end="625"
                     /protein_start="216"
                     /score="381.0"
                     /tool="antismash"
                     /translation="EGSENEFEEVQEEQTVNSMVPIWRKNKSELTDEDYEKFYAEKHYG
                     FDKPLTHVHISVDGAVRYNAILFVPENMPFDYYSKEYEKGLELYSNGVLIMNKCADLLP
                     DHFSFVKGMVDSEDLSLNISREMLQHDRQLKLIAKNISKKIKSELQSLLKKDREKYETF
                     YKSFGRQLKFGVYNDFGANKDQLKDLLLFYSSKEKKLVSLDEYVSRMPEEQKFIYYATG
                     DSYDRIEKLPQTEMVADKGYEILYFTEDIDEFAIKMLASYQEKEFKSVSSGDLGIDTDE
                     DQKQSEEEESKYKDLFEEMKNILSDKVKNVRISKRLKSHPVCLAADGEVTIEMEKILNA
                     MPDSQNVKAEKVLEINPNHEVFQTLQDAFEQDKEKLSLYTNLLYNQALLIEGLPIQDPV
                     EFTNNICKVM"
     PFAM_domain     complement(2717..3085)
                     /aSDomain="HATPase_c_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13589.8"
                     /description="Histidine kinase-, DNA gyrase B-, and
                     HSP90-like ATPase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4096_0607"
                     /evalue="4.20E-12"
                     /label="ctg1_4096"
                     /locus_tag="ctg1_4096"
                     /protein_end="148"
                     /protein_start="25"
                     /score="46.3"
                     /tool="antismash"
                     /translation="EIFLRELISNSSDAIDKIYYKALTDDALTFDKDSYYIKVAADKDA
                     RTLTISDTGIGMTKDELEQHLGTIAKSGSLAFKKENELKDGHDIIGQFGVGFYAAFMVA
                     DVVTVISKALGSEEAYKWE"
     CDS             complement(3328..3579)
                     /locus_tag="ctg1_4097"
                     /transl_table=11
                     /translation="LKVQHKKELKFYCIVTIPSAFVVLTVISFLLQEITFPVTASAFLN
                     ASWHNLLFLIPFGLFFYPVHIWMKREFGRWNDTEKKRG"
     CDS             3696..4517
                     /NRPS_PKS="Domain: PKS_KR (7-160). E-value: 2.6e-09. Score:
                     29.1. Matches aSDomain: nrpspksdomains_ctg1_4098_PKS_KR.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     247.9; E-value: 1.8e-75)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_4098"
                     /sec_met_domain="adh_short (E-value: 1.4e-31, bitscore:
                     107.9, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 6.4e-36, bitscore:
                     122.5, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGRLENKTAVITGAATGIGQATAEVFANEGARVIIGDINKDQMEE
                     TVDAIRKNGGQAESFHLDVSDENSVKAFADQIKDACGTIDILFNNAGVDQEGGKVHEYP
                     VDLFDRIIAVDLRGTFLCSKYLIPLMLENGGSIINTSSMSGRAADLDRSGYNAAKGGIT
                     NLTKAMAIDYARNGIRVNSISPGTIETPLIDKLAGTKEQEMGEQFREANKWITPLGRLG
                     QPKEMATVALFLASDDSSYVTGEDITADGGIMAYTWPGKMLIEEKWKEETK"
     aSDomain        3717..4175
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_4098_PKS_KR.1"
                     /evalue="2.60E-09"
                     /label="ctg1_4098_PKS_KR.1"
                     /locus_tag="ctg1_4098"
                     /protein_end="160"
                     /protein_start="7"
                     /score="29.1"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="TAVITGAATGIGQATAEVFANEGARVIIGDINKDQMEETVDAIRK
                     NGGQAESFHLDVSDENSVKAFADQIKDACGTIDILFNNAGVDQEGGKVHEYPVDLFDRI
                     IAVDLRGTFLCSKYLIPLMLENGGSIINTSSMSGRAADLDRSGYNAAKG"
     CDS_motif       3723..3800
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_4098_0001"
                     /evalue="1.80E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg1_4098"
                     /protein_end="35"
                     /protein_start="9"
                     /score="17.4"
                     /tool="antismash"
                     /translation="VITGAATGIGQATAEVFANEGARVII"
     PFAM_domain     3732..4454
                     /aSDomain="adh_short_C2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13561.8"
                     /description="Enoyl-(Acyl carrier protein) reductase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4098_0609"
                     /evalue="4.30E-72"
                     /label="ctg1_4098"
                     /locus_tag="ctg1_4098"
                     /protein_end="253"
                     /protein_start="12"
                     /score="242.6"
                     /tool="antismash"
                     /translation="GAATGIGQATAEVFANEGARVIIGDINKDQMEETVDAIRKNGGQA
                     ESFHLDVSDENSVKAFADQIKDACGTIDILFNNAGVDQEGGKVHEYPVDLFDRIIAVDL
                     RGTFLCSKYLIPLMLENGGSIINTSSMSGRAADLDRSGYNAAKGGITNLTKAMAIDYAR
                     NGIRVNSISPGTIETPLIDKLAGTKEQEMGEQFREANKWITPLGRLGQPKEMATVALFL
                     ASDDSSYVTGEDITADGGI"
     CDS             complement(4546..5688)
                     /gene_functions="regulatory (smcogs) SMCOG1057:TetR family
                     transcriptional regulator (Score: 40; E-value: 9.1e-12)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_4099"
                     /transl_table=11
                     /translation="VPESAEAQVKEALLALLKDRDIQHITMKEIAEKAKVSRGSLYLYY
                     EDKFSIIEDVIEDMKEGLGKALFDAFSHMDTLHLNKKRQTVHPTLSFVHEHRSFFSVMM
                     NRGHFHRFFKDVFQQDVLLAPIHVNLTPIERDIYGHYRALYTYAIILYWLNEDAAASPE
                     AISQKVWELVSQKRFYWLFGKAVPGEREKEKQIDRRVVRTREALQKAFLDVLAEKQDYA
                     GITISDITRKSNIRRATFYDHYANKEELLQTMIQRSCAEIIDHLTIASSPNEFSLKEAE
                     KALAILLSALSNMPIVHFLNREWGVPHVIPDMFKALESFYLHQQTDIHAEKKLYAHYVS
                     AMIIGLLLYRLDEGKAHPPEVLAREFLQFLDVKKYKVVLL"
     PFAM_domain     complement(4933..5046)
                     /aSDomain="TetR_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00440.25"
                     /description="Bacterial regulatory proteins, tetR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4099_0611"
                     /evalue="7.10E-07"
                     /label="ctg1_4099"
                     /locus_tag="ctg1_4099"
                     /protein_end="252"
                     /protein_start="214"
                     /score="29.0"
                     /tool="antismash"
                     /translation="LAEKQDYAGITISDITRKSNIRRATFYDHYANKEELLQ"
     PFAM_domain     complement(5530..5655)
                     /aSDomain="TetR_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00440.25"
                     /description="Bacterial regulatory proteins, tetR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4099_0610"
                     /evalue="2.40E-07"
                     /label="ctg1_4099"
                     /locus_tag="ctg1_4099"
                     /protein_end="53"
                     /protein_start="11"
                     /score="30.5"
                     /tool="antismash"
                     /translation="ALLALLKDRDIQHITMKEIAEKAKVSRGSLYLYYEDKFSIIE"
     CDS             5831..7168
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017:aldehyde dehydrogenase (Score: 299.5; E-value:
                     5.6e-91)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_4100"
                     /transl_table=11
                     /translation="MEQQVKDDIQRVFQLQKKQQKALRASTAEQRREKLQRFLDSVIAH
                     EEEIIEAIRKDVRKPYHEVKKAEIEGTKKAIRDNMNNLEQWMAPKEVGSSLSPDANGIL
                     MYEPKGVTLILGPWNYPFMLTMAPLAASLAAGNSAIVKLSDFTMNTSNIAAKVIRDAFD
                     EKEVAIFEGEVEVATELLDQPFDHIFFTGSTNVGKIVMTAAAKHLASVTLELGGKSPTI
                     IDSEYDLMDAAKKIAVGKFVNAGQTCIAPDYLFIKKDVQDRFAGILQTVVNAGFMEDDH
                     TPDRSKFTQIVNDRNFNRVKDLFDDAIERGAEVVFGGVFDASDRTISPTVLKNVTPDMK
                     IMQEEIFASILPMMNYEDIDEVIDYVNDRDKPLALYVFSKNQDLIDNVLQHTTSGNAAI
                     NDVVVHFSDVNLPFGGVNTSGIGSYHGVYGFKEFSHEKGVFIQAAE"
     PFAM_domain     5843..7141
                     /aSDomain="Aldedh"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00171.24"
                     /description="Aldehyde dehydrogenase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4100_0612"
                     /evalue="1.20E-97"
                     /label="ctg1_4100"
                     /locus_tag="ctg1_4100"
                     /protein_end="437"
                     /protein_start="4"
                     /score="327.5"
                     /tool="antismash"
                     /translation="VKDDIQRVFQLQKKQQKALRASTAEQRREKLQRFLDSVIAHEEEI
                     IEAIRKDVRKPYHEVKKAEIEGTKKAIRDNMNNLEQWMAPKEVGSSLSPDANGILMYEP
                     KGVTLILGPWNYPFMLTMAPLAASLAAGNSAIVKLSDFTMNTSNIAAKVIRDAFDEKEV
                     AIFEGEVEVATELLDQPFDHIFFTGSTNVGKIVMTAAAKHLASVTLELGGKSPTIIDSE
                     YDLMDAAKKIAVGKFVNAGQTCIAPDYLFIKKDVQDRFAGILQTVVNAGFMEDDHTPDR
                     SKFTQIVNDRNFNRVKDLFDDAIERGAEVVFGGVFDASDRTISPTVLKNVTPDMKIMQE
                     EIFASILPMMNYEDIDEVIDYVNDRDKPLALYVFSKNQDLIDNVLQHTTSGNAAINDVV
                     VHFSDVNLPFGGVNTSGIGSYHGVYGFKEFSHEK"
     CDS             complement(7207..7686)
                     /locus_tag="ctg1_4101"
                     /transl_table=11
                     /translation="MNIIPTCQVPKDLVSAFFQKHWGSPQMVISSGIYNCDELDGYGML
                     NDDNQIVGLITYIFEEDACEIISLDSVIENKGIGTALLEKAEEACRERNIKQIKLITTN
                     DNIHALAFYQKRGYRLDRLFVNAVETARKMKPEIPLLADNKIPIRDELLLVKELQ"
     PFAM_domain     complement(7333..7635)
                     /aSDomain="Acetyltransf_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00583.27"
                     /description="Acetyltransferase (GNAT) family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4101_0613"
                     /evalue="1.10E-12"
                     /label="ctg1_4101"
                     /locus_tag="ctg1_4101"
                     /protein_end="118"
                     /protein_start="17"
                     /score="48.4"
                     /tool="antismash"
                     /translation="FQKHWGSPQMVISSGIYNCDELDGYGMLNDDNQIVGLITYIFEED
                     ACEIISLDSVIENKGIGTALLEKAEEACRERNIKQIKLITTNDNIHALAFYQKRGY"
     CDS             complement(7766..8758)
                     /locus_tag="ctg1_4102"
                     /transl_table=11
                     /translation="MSAVTESVLESIISPVTMSEFLEEYWPVKPLVARGEVERFTSIPG
                     FEKVRTLENVLAIYNNPVMVVGDAVIEESEGITDRFLVSPAEALEWYEKGAALEFDFTD
                     LFIPQVRRWIEKLKAELRLPAGTSSKAIVYAAKNGGGFKAHFDAYTNLIFQIQGEKTWK
                     LAKNENVSNPMQHYDLSEAPYYPDDLQSYWKGDPPKEDLPDAEIVNLTPGTMLYLPRGL
                     WHSTKSDQATLALNITFGQPAWLDLMLAALRKKLISDNRFRELAVNHQSLHESSKSELN
                     GYLESLIQTLSENAETLTPEQIFQSQDSDFDPYQSTQLVFRQLLTSYKF"
     PFAM_domain     complement(7856..8704)
                     /aSDomain="Cupin_4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08007.14"
                     /description="Cupin superfamily protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4102_0614"
                     /evalue="4.00E-21"
                     /label="ctg1_4102"
                     /locus_tag="ctg1_4102"
                     /protein_end="301"
                     /protein_start="18"
                     /score="75.9"
                     /tool="antismash"
                     /translation="SEFLEEYWPVKPLVARGEVERFTSIPGFEKVRTLENVLAIYNNPV
                     MVVGDAVIEESEGITDRFLVSPAEALEWYEKGAALEFDFTDLFIPQVRRWIEKLKAELR
                     LPAGTSSKAIVYAAKNGGGFKAHFDAYTNLIFQIQGEKTWKLAKNENVSNPMQHYDLSE
                     APYYPDDLQSYWKGDPPKEDLPDAEIVNLTPGTMLYLPRGLWHSTKSDQATLALNITFG
                     QPAWLDLMLAALRKKLISDNRFRELAVNHQSLHESSKSELNGYLESLIQTLSENAETLT
                     PE"
     CDS             9267..10001
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 103.3; E-value:
                     2.5e-31)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_4103"
                     /transl_table=11
                     /translation="MITAEECRTYKEFVDLYQSYLYPLLGARLSRMYSPKNKVIIDMGT
                     GPGYLSIQLAKRTNAHVHAVDINPAMHEIAQEEAKKSGVSSLISFDLEDVHHLSYADQY
                     ADFIVSYSCLHHWEDVVKGLKECYRVLAPGGKIVILDTFNPQGSHLEIMRKQIKEPEYF
                     RFVREAFEESYSFEDIHQFVQDAGIPNYSLETFHFLPEDFIESLDELEDAPLWEQNDQS
                     TDHEIESVTWMLTIEKEKEGAL"
     PFAM_domain     9390..9683
                     /aSDomain="Methyltransf_11"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08241.14"
                     /description="Methyltransferase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4103_0615"
                     /evalue="9.30E-23"
                     /label="ctg1_4103"
                     /locus_tag="ctg1_4103"
                     /protein_end="139"
                     /protein_start="41"
                     /score="80.8"
                     /tool="antismash"
                     /translation="DMGTGPGYLSIQLAKRTNAHVHAVDINPAMHEIAQEEAKKSGVSS
                     LISFDLEDVHHLSYADQYADFIVSYSCLHHWEDVVKGLKECYRVLAPGGKIVI"
     CDS             10001..10270
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_4104"
                     /sec_met_domain="PF05402 (E-value: 6e-11, bitscore: 40.4,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 5.8e-08,
                     bitscore: 30.6, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 5.6e-08, bitscore:
                     30.4, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINESTVLSKNPEMPSRKYLKSIIIEPGITLNEMASDIYNHIDGK
                     VSIHDICSKIVNEYDVDYQTCLEDCMELFELLIDHEAIKVKQGA"
     PFAM_domain     10085..10243
                     /aSDomain="PqqD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05402.14"
                     /description="Coenzyme PQQ synthesis protein D (PqqD)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4104_0616"
                     /evalue="1.20E-10"
                     /label="ctg1_4104"
                     /locus_tag="ctg1_4104"
                     /protein_end="81"
                     /protein_start="28"
                     /score="41.6"
                     /tool="antismash"
                     /translation="ITLNEMASDIYNHIDGKVSIHDICSKIVNEYDVDYQTCLEDCMEL
                     FELLIDHE"
     CDS             10274..10756
                     /locus_tag="ctg1_4105"
                     /transl_table=11
                     /translation="LEKQKVLALPDDVHELSTHRSKSIVNYIITLLAFAKKQGLTHQDI
                     VSWIHEQYEERGYYDEWRHINSQQPVGSFVELFIKGRRLLYDKIELFETEDKYVVNTHT
                     WYEKEPSEAFFYFEIDPEEFSAYASILAIENAKRLGIKIDIVKETDVETAYIYKHQ"
     CDS             10777..13020
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177:asparagine synthase (glutamine-hydrolyzing)
                     (Score: 407.1; E-value: 2.2e-123)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_4106"
                     /sec_met_domain="Asn_synthase (E-value: 9.2e-94, bitscore:
                     312.9, seeds: 78, tool: rule-based-clusters)"
                     /sec_met_domain="GATase_7 (E-value: 3.4e-43, bitscore:
                     144.4, seeds: 307, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCGLAGIINLAAPRSQECTFHILKGMADAISYRGPDDEQYHIDSK
                     VGFAFRRLSILDLVNGQQPFLNEDGSIVVMVNGEIYNYKELKASLHNHMFKTTSDCEVI
                     VHLYEEKGIGFVDDIIGMFSIAIWDKNKNKVFLVRDRFGIKPLFYTELKHELIFASEIK
                     SLFSHPHCPRQFNWKEALSDIWLSGEAASNHKETTSFFVNIQNLDAGHYLEINLTTNER
                     KTASYWSLQDILLRQGYRENLHPDDLIEGYRELLADSVHRCLQSDVEVGLFLSGGIDSA
                     AVAHFAAEKQDLHTFTVLSQSTFTNEDAKYAHWLAKDLHLPNHQVLYQLGNDELLQPES
                     YKHLLWICETPFCGPEQLYKFHLHKYAKAIRPNLKVMLTGQGSDEFNGGYSTTLSPAEN
                     PSWEGFIESVNTMEMNRLHRLQGNIFRVWEEHFGLSPINLSYLKSNDSSQADPWQSYVL
                     TKYRDLQMYNCWHEDRIAAANHIENRVPFLDHRLVEWVCGIPDGLRKDLLWDKSVLRKS
                     LTNELHTSYTHRPKVPFFYGKDVRYTHKMMFHLLKKNNYQLIEEAFSHSDASSIIQVEH
                     IHAIMTYLEDDPEFTNFEFLLRLVNMGLLSKMTKETPSVQLDITSHLESITIKDWHSQE
                     GDIASRLNISANKCEGQDILALNPGVTLLRPESDSEHCIYIAEEGFIQFIVSEEDVGAW
                     LHILCDINGKDTLHTILDRHGVSLEEVAKYIQEAIEHNIILIKQKNLPEGAYR"
     aSDomain        10780..12378
                     /aSDomain="TIGR01536"
                     /aSTool="tigrfam"
                     /description="asn_synth_AEB: asparagine synthase
                     (glutamine-hydrolyzing)"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_4106_0128"
                     /evalue="3.50E-108"
                     /identifier="TIGR01536"
                     /label="ctg1_4106"
                     /locus_tag="ctg1_4106"
                     /protein_end="534"
                     /protein_start="1"
                     /score="360.8"
                     /tool="antismash"
                     /translation="CGLAGIINLAAPRSQECTFHILKGMADAISYRGPDDEQYHIDSKV
                     GFAFRRLSILDLVNGQQPFLNEDGSIVVMVNGEIYNYKELKASLHNHMFKTTSDCEVIV
                     HLYEEKGIGFVDDIIGMFSIAIWDKNKNKVFLVRDRFGIKPLFYTELKHELIFASEIKS
                     LFSHPHCPRQFNWKEALSDIWLSGEAASNHKETTSFFVNIQNLDAGHYLEINLTTNERK
                     TASYWSLQDILLRQGYRENLHPDDLIEGYRELLADSVHRCLQSDVEVGLFLSGGIDSAA
                     VAHFAAEKQDLHTFTVLSQSTFTNEDAKYAHWLAKDLHLPNHQVLYQLGNDELLQPESY
                     KHLLWICETPFCGPEQLYKFHLHKYAKAIRPNLKVMLTGQGSDEFNGGYSTTLSPAENP
                     SWEGFIESVNTMEMNRLHRLQGNIFRVWEEHFGLSPINLSYLKSNDSSQADPWQSYVLT
                     KYRDLQMYNCWHEDRIAAANHIENRVPFLDHRLVEWVCGIPDGLRKDLLWDKSVLRKSL
                     TNELHTSYTHRPKVPF"
     PFAM_domain     10927..11271
                     /aSDomain="GATase_7"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13537.8"
                     /description="Glutamine amidotransferase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4106_0617"
                     /evalue="1.60E-42"
                     /label="ctg1_4106"
                     /locus_tag="ctg1_4106"
                     /protein_end="165"
                     /protein_start="50"
                     /score="144.4"
                     /tool="antismash"
                     /translation="RRLSILDLVNGQQPFLNEDGSIVVMVNGEIYNYKELKASLHNHMF
                     KTTSDCEVIVHLYEEKGIGFVDDIIGMFSIAIWDKNKNKVFLVRDRFGIKPLFYTELKH
                     ELIFASEIKSL"
     PFAM_domain     11530..12672
                     /aSDomain="Asn_synthase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00733.23"
                     /description="Asparagine synthase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4106_0618"
                     /evalue="4.20E-93"
                     /label="ctg1_4106"
                     /locus_tag="ctg1_4106"
                     /protein_end="632"
                     /protein_start="251"
                     /score="312.9"
                     /tool="antismash"
                     /translation="YRELLADSVHRCLQSDVEVGLFLSGGIDSAAVAHFAAEKQDLHTF
                     TVLSQSTFTNEDAKYAHWLAKDLHLPNHQVLYQLGNDELLQPESYKHLLWICETPFCGP
                     EQLYKFHLHKYAKAIRPNLKVMLTGQGSDEFNGGYSTTLSPAENPSWEGFIESVNTMEM
                     NRLHRLQGNIFRVWEEHFGLSPINLSYLKSNDSSQADPWQSYVLTKYRDLQMYNCWHED
                     RIAAANHIENRVPFLDHRLVEWVCGIPDGLRKDLLWDKSVLRKSLTNELHTSYTHRPKV
                     PFFYGKDVRYTHKMMFHLLKKNNYQLIEEAFSHSDASSIIQVEHIHAIMTYLEDDPEFT
                     NFEFLLRLVNMGLLSKMTKETPSVQLDITSHLESITIKDWH"
     CDS             13017..14216
                     /gene_functions="transport (smcogs) SMCOG1202:major
                     facilitator transporter (Score: 97.4; E-value: 1.1e-29)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_4107"
                     /transl_table=11
                     /translation="MSIFYSFSALRGLAMGIFSPIWILYLISKDYDFLQIGLMGAVLEI
                     AKLIFEVPSGVFADRYGIKISIASSFFFSILTWAFFPFIDSAAICILAMIIWALSDSLI
                     SGSFETWMSRVAGEDRFGKEMMKNTQLLITFLIIGSIASGYLYSLNIYFPFLLVMVIYL
                     LLFIWMSVFIKVPSVSETNHGDQNQHDSIKIIKESLKIIFNKKRVLLIVIAGFFTATAY
                     DTISRYWQPFLSDLGFSEKSLGYIFALGGFTALVLLTLTIRFEKKIEKNPYLALTSLDS
                     MGMVMTFLLSRAFRPLGIPCTAFLLAIEDIHHPIVTSYLNKFFPDSYKNTLFSLNSGVG
                     AIGEILSGVIFGIISAAFGLSAMFVVVAVFLLIPIILYTIVPKIKDNDMKVQIEKSQQV
                     "
     PFAM_domain     13041..13886
                     /aSDomain="MFS_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07690.18"
                     /description="Major Facilitator Superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4107_0619"
                     /evalue="3.40E-17"
                     /label="ctg1_4107"
                     /locus_tag="ctg1_4107"
                     /protein_end="290"
                     /protein_start="8"
                     /score="62.5"
                     /tool="antismash"
                     /translation="ALRGLAMGIFSPIWILYLISKDYDFLQIGLMGAVLEIAKLIFEVP
                     SGVFADRYGIKISIASSFFFSILTWAFFPFIDSAAICILAMIIWALSDSLISGSFETWM
                     SRVAGEDRFGKEMMKNTQLLITFLIIGSIASGYLYSLNIYFPFLLVMVIYLLLFIWMSV
                     FIKVPSVSETNHGDQNQHDSIKIIKESLKIIFNKKRVLLIVIAGFFTATAYDTISRYWQ
                     PFLSDLGFSEKSLGYIFALGGFTALVLLTLTIRFEKKIEKNPYLALTSLDSMGMVMTFL
                     L"
     CDS             complement(14280..15512)
                     /locus_tag="ctg1_4108"
                     /transl_table=11
                     /translation="MVKSFRMKALIAGAAVAAAVSAGAVSDVPAAKVLQPTAAYAAETV
                     FSQNNGASGFLPGRYDVQAMAPAMFNWSRESRFAGNTDGTLKWQNDIRTTPQNGAGAVI
                     DGDGTVYLHSRDGEMKAFNPDGSVKWVTGNLGKTYTQSPVLGTNGVIYLASYDKKIYFI
                     DKETGEILTTVPLSGGPSSETVIGSDGTLYFSTLDNYVHAIKPTSKSTWTERWKLKTNG
                     VVSSVPVLAKNGTVYVGTYNYVFYAINSGTGQVKWSRTTSNAFKGYPVIDKDGNIYAGN
                     QDGQLYAYTSTGSLKWTFPLNGFSSSSPAIDHNGNIYIGSGSGELFSISKNGDMNWSFY
                     TDGPVRTAPLIDAKGTVYFGSDDMKVYAADANGNELWSYQTDSNVVSSPQLAEDGTLYI
                     GSYTKLMAFGK"
     PFAM_domain     complement(14343..14450)
                     /aSDomain="PQQ"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01011.23"
                     /description="PQQ enzyme repeat"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4108_0622"
                     /evalue="1.70E-08"
                     /label="ctg1_4108"
                     /locus_tag="ctg1_4108"
                     /protein_end="390"
                     /protein_start="354"
                     /score="33.9"
                     /tool="antismash"
                     /translation="GTVYFGSDDMKVYAADANGNELWSYQTDSNVVSSPQ"
     PFAM_domain     complement(14583..14690)
                     /aSDomain="PQQ"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01011.23"
                     /description="PQQ enzyme repeat"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4108_0621"
                     /evalue="5.90E-07"
                     /label="ctg1_4108"
                     /locus_tag="ctg1_4108"
                     /protein_end="310"
                     /protein_start="274"
                     /score="29.1"
                     /tool="antismash"
                     /translation="GNIYAGNQDGQLYAYTSTGSLKWTFPLNGFSSSSPA"
     PFAM_domain     complement(14700..15269)
                     /aSDomain="PQQ_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13360.8"
                     /description="PQQ-like domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4108_0620"
                     /evalue="1.40E-13"
                     /label="ctg1_4108"
                     /locus_tag="ctg1_4108"
                     /protein_end="271"
                     /protein_start="81"
                     /score="51.2"
                     /tool="antismash"
                     /translation="TDGTLKWQNDIRTTPQNGAGAVIDGDGTVYLHSRDGEMKAFNPDG
                     SVKWVTGNLGKTYTQSPVLGTNGVIYLASYDKKIYFIDKETGEILTTVPLSGGPSSETV
                     IGSDGTLYFSTLDNYVHAIKPTSKSTWTERWKLKTNGVVSSVPVLAKNGTVYVGTYNYV
                     FYAINSGTGQVKWSRTTSNAFKGYPVI"
     CDS             complement(15613..16038)
                     /locus_tag="ctg1_4109"
                     /transl_table=11
                     /translation="MSKKNSVAIMTTISAFLFCAVIVAASLSPLAGTGAAANQFNSAGM
                     WSAVGMILVLYFIPFLVYMLGVDAMRYVMAVLCGFGLLIHLSSAGFILMFSFFSDHLLS
                     EVIFVLGVSLAAAAVNVIWFVAAFRSGAEKTSVNTLT"
     PFAM_domain     complement(15649..16035)
                     /aSDomain="DUF5391"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF17369.4"
                     /description="Family of unknown function (DUF5391)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4109_0623"
                     /evalue="1.20E-39"
                     /label="ctg1_4109"
                     /locus_tag="ctg1_4109"
                     /protein_end="130"
                     /protein_start="1"
                     /score="135.8"
                     /tool="antismash"
                     /translation="SKKNSVAIMTTISAFLFCAVIVAASLSPLAGTGAAANQFNSAGMW
                     SAVGMILVLYFIPFLVYMLGVDAMRYVMAVLCGFGLLIHLSSAGFILMFSFFSDHLLSE
                     VIFVLGVSLAAAAVNVIWFVAAFRS"
     CDS             16295..16750
                     /locus_tag="ctg1_4110"
                     /transl_table=11
                     /translation="MEKPAGFWIRFLAYFIDGIIVSVPSYIILFIINSVFVAGAVATNP
                     YMTEEEYLVKYMTLAFLPTMLIMIVISVLYYGLLTASKMQGTLGKKILGLKVVNEQGER
                     VSVGQGIGRYFAYILSGIIFYIGFIMIAFGEKKGLHDIICKTRVVYK"
     PFAM_domain     16304..16726
                     /aSDomain="RDD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06271.14"
                     /description="RDD family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4110_0624"
                     /evalue="9.50E-27"
                     /label="ctg1_4110"
                     /locus_tag="ctg1_4110"
                     /protein_end="144"
                     /protein_start="3"
                     /score="94.1"
                     /tool="antismash"
                     /translation="PAGFWIRFLAYFIDGIIVSVPSYIILFIINSVFVAGAVATNPYMT
                     EEEYLVKYMTLAFLPTMLIMIVISVLYYGLLTASKMQGTLGKKILGLKVVNEQGERVSV
                     GQGIGRYFAYILSGIIFYIGFIMIAFGEKKGLHDIIC"
     CDS             complement(16780..17988)
                     /locus_tag="ctg1_4111"
                     /transl_table=11
                     /translation="MSSLQPTLTNERIGVLDVLRGMAIFGILFVNLAHFSYPDMYLSML
                     GKENFFMDKWSEADFAAADILKFFIQTKCILLFSFLFGFGMVVMMERAENKGKRFVPLY
                     VRRLMALLLFGTIHAFLIWDGDILTEYALLGFVLLLFRKAKPKTLLIWAVSLYLLFSIP
                     FMLTSFDQSNGQEWVQAVTQQAKQAIHVYGSGSLKDIAEQRIHDRLVYMSSNGMLTYNP
                     LNYFFASIPYFSMFLLGAAAAKSRYLHEPEKHRKGLKRLWMAGLVIGIGAQVLYSVTDK
                     EICLLIGAPFLMFFYVTTVVYLYHKTRVRTVLQSFSAVGRMAFTNYLMQSIVCTWIFYH
                     YGLGLYGKVYPAAGVLITIAVCAVQMVFSHLWLRVFRMGPFEWLWRSATYLSWQPIAKK
                     TKV"
     PFAM_domain     complement(16816..17265)
                     /aSDomain="DUF418"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04235.14"
                     /description="Protein of unknown function (DUF418)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4111_0625"
                     /evalue="3.90E-50"
                     /label="ctg1_4111"
                     /locus_tag="ctg1_4111"
                     /protein_end="391"
                     /protein_start="241"
                     /score="170.0"
                     /tool="antismash"
                     /translation="AAKSRYLHEPEKHRKGLKRLWMAGLVIGIGAQVLYSVTDKEICLL
                     IGAPFLMFFYVTTVVYLYHKTRVRTVLQSFSAVGRMAFTNYLMQSIVCTWIFYHYGLGL
                     YGKVYPAAGVLITIAVCAVQMVFSHLWLRVFRMGPFEWLWRSATYL"
     CDS             complement(18096..19109)
                     /locus_tag="ctg1_4112"
                     /transl_table=11
                     /translation="MKTLCTHSLPKEKMPYLLRSGEGERYLFGRQVATVMANGRSTGDL
                     FEIVLLSGGKGDAFPLHVHKDTHEGILVLDGKLELTLDGERYLLISGDYANIPAGTPHS
                     YRMQSHRTRLVSYTMKGNVAHLYSVIGNPYDHAEHPPYASEEVSNERFAEAAAVADIVF
                     LDEAKPACSAKLAELTELPDGAVPYVLESGEGDRLLTGDQLHRIVAAQKNTDGQFIVVS
                     SEGPKGDRIVDHYHEYHTETFYCLEGQMTMWTDGQEIQLNPGDFLHVPANTVHSYRLDS
                     HYTKMVGVLVPGLFEPFFRTLGDPYEGHIFPCEPQALRFDRILQNIEALDLKVMKP"
     PFAM_domain     complement(18267..18434)
                     /aSDomain="Cupin_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07883.13"
                     /description="Cupin domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4112_0627"
                     /evalue="5.40E-16"
                     /label="ctg1_4112"
                     /locus_tag="ctg1_4112"
                     /protein_end="281"
                     /protein_start="225"
                     /score="58.1"
                     /tool="antismash"
                     /translation="PKGDRIVDHYHEYHTETFYCLEGQMTMWTDGQEIQLNPGDFLHVP
                     ANTVHSYRLDS"
     PFAM_domain     complement(18780..18947)
                     /aSDomain="Cupin_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07883.13"
                     /description="Cupin domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4112_0626"
                     /evalue="7.60E-13"
                     /label="ctg1_4112"
                     /locus_tag="ctg1_4112"
                     /protein_end="110"
                     /protein_start="54"
                     /score="48.1"
                     /tool="antismash"
                     /translation="KGDAFPLHVHKDTHEGILVLDGKLELTLDGERYLLISGDYANIPA
                     GTPHSYRMQSH"
     CDS             complement(19203..19778)
                     /gene_functions="regulatory (smcogs) SMCOG1057:TetR family
                     transcriptional regulator (Score: 63.1; E-value: 7.5e-19)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_4113"
                     /transl_table=11
                     /translation="MTSRGDSREKILHTASRLFQLQGYHATGLNQIVKESGAPKGSLYH
                     FFPNGKEELAIEAVTYTGKIVEHLIQQSMDESSDPVEAIQLFIKKTASQFDNTESIKGI
                     PVGLLASETALISEPLRTVCMKVFKSWEAVFARKLMENGFAEEEANQLGTLINSMIEGG
                     IMLSLTNKDKTPLLLIAEQIPVLVRKKG"
     PFAM_domain     complement(19605..19748)
                     /aSDomain="TetR_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00440.25"
                     /description="Bacterial regulatory proteins, tetR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4113_0628"
                     /evalue="7.10E-16"
                     /label="ctg1_4113"
                     /locus_tag="ctg1_4113"
                     /protein_end="58"
                     /protein_start="10"
                     /score="57.8"
                     /tool="antismash"
                     /translation="ILHTASRLFQLQGYHATGLNQIVKESGAPKGSLYHFFPNGKEELA
                     IEA"
ORIGIN
        1 tcagcatgct gctccttggc gcgattttcg gttctgcctt gagcggcaca tgctcagacc
       61 gctggggcag gagaaaggtt gtatttgtcc tttccatcat ttttattatc ggtgcgctcg
      121 cttgcgcatt ttctcaaaca atcggcatgc tgattgcatc tagggtgata ctcgggttgg
      181 ccgtcggcgg ttcaacggca cttgtgcccg tgtatctttc cgaaatggca ccgacgaaaa
      241 ttcgcgggac actcggcaca atgaacaact taatgattgt caccgggatt ttgctcgcct
      301 atatcgttaa ctacctgttc acaccgtttg aagcgtggcg ctggatggtc ggtctggctg
      361 cagtgcctgc cgtgcttcta ttaatcggca tcgccttcat gccggaatcg ccaagatggc
      421 tcgtgaagcg cggcagcgaa gaagaagcga gacgcatcat gaacatcact catgacccca
      481 aagacatcga aatggaattg gcagagatga agcaagggga agcggagaaa aaagaaacga
      541 cacttggcgt gctgaaagcc aagtggattc gccctatgct tctgattggc gtcggccttg
      601 ccattttcca gcaggcagtc ggcattaaca cggtcatcta ctacgcgcca accattttta
      661 cgaaggccgg tcttggcaca tcagcttcgg cgctcggcac aatgggaatc ggcatcctca
      721 acgtcatcat gtgtatcact gccatgatct taattgaccg tgtcggccgc aaaaaacttc
      781 tgatctgggg aagtgtcggc atcacactga gccttgctgc tttatcaggc gtgctcctga
      841 cactggggct ttccgcatca acagcgtgga tgacagtagt ctttctcggt gtctatatcg
      901 tcttttacca ggcgacatgg ggtccggtag tgtgggtgct catgcctgag ctcttcccgt
      961 ccaaagcacg cggagccgcg acagggttca cgactttggt gttatcggcg gctaacctga
     1021 tcgtgtcgct tgtcttcccg ctgatgctaa gcgcgatggg catcgcatgg gtctttatgg
     1081 ttttctcagt catttgtctt ctctcatttt tcttcgcgtt ctacatggta ccggaaacca
     1141 aagggaaaag cttggaggaa attgaagcaa gcctgaaaaa acggtttaaa aagaagaaaa
     1201 gcacccaaaa ccaagtgctg aatgagcgta cattataaaa aaaggaatcg tctccttatg
     1261 agacgattcc tttttctgtt tacaccatga ccttgcaaat attgttcgta aattccacag
     1321 ggtcctgaat cggcaggcct tcgatgagga gcgcctgatt gtacagaagg tttgtgtaca
     1381 ggctcagctt ctctttatct tgttcaaacg cgtcctgcag tgtttggaat acctcgtgat
     1441 ttgggttgat ttccagcact ttttccgcct tcacattttg gctgtcaggc atcgcattta
     1501 agattttttc catctcaatt gtcacttcgc cgtcagcagc aaggcagact ggatgtgatt
     1561 taagccgttt tgagattctg acgtttttca ctttgtctga cagaatgttt ttcatttcct
     1621 caaacagatc cttatacttg ctttcctctt cctcggactg cttttgatcc tcatccgtgt
     1681 ctatgccaag gtctccgctt gatacggact tgaattcttt ttcctgataa gaagccagca
     1741 ttttaattgc aaactcatcg atgtcctcag taaagtagag gatttcatag cctttgtccg
     1801 ccaccatttc cgtttgcggc agtttctcaa tgcggtcgta agaatcaccg gtcgcgtaat
     1861 aaatgaattt ctgctcctct ggcattctgg aaacatactc gtctaagctg accagttttt
     1921 tctcttttga agagtagaat aagaggagat ccttcaattg atccttattc gcgccaaaat
     1981 cattgtacac gccgaatttc agctgtctgc cgaacgactt gtagaacgtc tcgtatttct
     2041 cgcggtcttt tttcaacagg ctttgcagct cgcttttgat tttcttgctg atgtttttcg
     2101 cgatcagctt cagctggcgg tcatgctgca gcatttctct ggaaatattc agcgacagat
     2161 cctcagaatc gaccatgccc ttcacaaagc tgaagtggtc cggtagcagg tctgcgcact
     2221 tattcatgat cagcacgcca ttggaataca gctccaagcc tttctcatat tccttggaat
     2281 agtagtcaaa cggcatgttt tcagggacga atagaatcgc gttgtagcga accgctccat
     2341 ccacgctgat atgaacgtgt gtcagcggtt tatcaaaccc gtaatgcttt tcagcataga
     2401 atttttcata atcctcatct gtcagctcgc ttttgttttt tctccagatc ggcaccatgc
     2461 tgttgaccgt ctgctcttcc tgcacctctt caaattcatt ttcgctgcct tccttcggct
     2521 tattaatggt tgtatccatt ttgatcgggt agcgaatgaa gtcggagtac ttcttgatga
     2581 tcgcttttaa acgatattcc tctaaaaact cgtcatagct gtcatcttct gtgttctctt
     2641 tgattttcag gataatgtct gtaccgacag aatccttttc acacggctca atcgtatagc
     2701 cgtctgcacc cgcagactcc catttataag cctcttcgct gccaagcgct ttactgatga
     2761 ctgtcacgac atcggcaacc ataaatgccg cgtaaaaacc gacaccgaac tgcccgataa
     2821 tgtcatgtcc gtctttcagc tcgttttcct ttttaaacgc gagggaaccg ctttttgcaa
     2881 ttgttccaag atgctgttca agctcatcct ttgtcattcc gatccccgta tcagagatgg
     2941 ttaatgttct cgcatctttg tcagctgcga cctttatgta gtaactgtct ttatcaaacg
     3001 taagcgcatc gtccgtaagc gctttgtaat agattttgtc aatcgcatca ctcgaattgg
     3061 agattaactc gcgcaggaaa atttcttttt gggtataaat ggagttaatc atcatatcca
     3121 gcaagcgttt agactctgct ttaaactctt ttttcgccac tcttgatcgc tcctttacca
     3181 ttatgtaaac ccttttcagc atctatttat cacataagat gacaattgtc aattagattg
     3241 atagatgcat atatatgtaa atttaacatt agttggattt gttttcactc tttttctcac
     3301 tcattctcat aaaaaagaga ggcttcatca tcctctcttt ttttctgtgt cattccaacg
     3361 gccaaactcc cgcttcatcc atatatgcac cgggtagaaa aacaaaccga acggtatcaa
     3421 aaacaaaaga ttatgccatg aagcattcag aaatgcgctt gcagtcaccg ggaacgtaat
     3481 ctcttgcaat aaaaaagaga tgacagtcag cacaacaaat gcagatggaa tggtcacgat
     3541 gcaataaaac ttgagctcct tcttatgctg taccttcaaa catacaaacc tcccaacaat
     3601 ttctaattca tcttaacata tgctggcctt tcttttctcg catgtttatc actgcacata
     3661 gcgggaagac aaatagaaaa aggaggtctc gtatcatggg aagacttgaa aacaaaacag
     3721 cagttatcac aggcgccgcg acaggcattg gtcaagcgac ggcggaggtt tttgccaatg
     3781 aaggcgcgcg tgtgatcatc ggagatatca ataaagatca aatggaagaa acagttgacg
     3841 caatcagaaa aaacggagga caggccgaat cctttcacct cgatgtgtca gatgaaaaca
     3901 gtgtgaaagc atttgctgat caaatcaagg atgcatgcgg aacgattgat attctgttta
     3961 ataatgccgg cgttgatcag gaaggcggaa aggtgcacga atatccggtt gacctgtttg
     4021 accgcattat cgccgtcgac ctgcgcggca cattcctttg cagcaaatat ttgattccgc
     4081 tcatgctcga aaatggaggc tccatcatca acacctcctc catgtcaggc cgtgccgcgg
     4141 accttgaccg ctccggctac aacgccgcaa aaggcggtat caccaacctg acaaaggcaa
     4201 tggcaatcga ctacgcacga aacggcatcc gcgtcaattc catttcaccg ggcacgatcg
     4261 aaacaccgct gattgacaaa ttagcaggca caaaagaaca ggaaatgggc gaacaattcc
     4321 gcgaagccaa caaatggatc acgccgctcg gacgtcttgg ccagcccaaa gaaatggcaa
     4381 cagtggcact gttcctcgca tcagacgaca gctcatacgt cacaggagaa gacatcaccg
     4441 cagacggcgg catcatggcg tacacatggc ctgggaagat gctgattgag gagaaatgga
     4501 aggaagaaac gaaataagag agggagcccc ctctcttttt gtcttttaaa gcaatacaac
     4561 cttatatttc ttcacatcca aaaactgcaa aaactccctc gccagcactt caggcggatg
     4621 cgcctttcct tcatccagcc gatacaaaag caacccgata atcattgcgg atacataatg
     4681 ggcataaagc tttttctctg cgtgaatatc agtttgctga tgcagataaa acgattccag
     4741 cgctttgaac atatcaggta tcacatgagg aacaccccat tcccgattga gaaaatggac
     4801 aatgggcatg tttgacaaag cagaaagcag aatggcgagc gccttctccg cttcctttaa
     4861 ggaaaattca ttcgggctgg aggcaatcgt caggtgatca atgatctccg cacatgatcg
     4921 ctgtatcatg gtttggagca attcctcctt attggcatag tgatcataaa aggttgcacg
     4981 gcggatattg cttttacgcg taatatctga aatcgtgatg cccgcgtagt cttgtttctc
     5041 cgccaataca tccagaaatg ccttctgcag cgcctctctc gttcgaacca cccgcctgtc
     5101 gatttgcttc tccttctctc gctctcctgg cacagctttt ccaaacagcc aataaaaccg
     5161 cttttgagaa acaagctccc ataccttctg gctgatggct tcaggagacg cggccgcatc
     5221 ctcattcagc caatacagga taatcgcgta cgtgtacaag gcccgataat gtccataaat
     5281 gtcccgttca atcggcgtta aattcacatg gatcggagcc agcagcacat cctgctgaaa
     5341 cacatcctta aaaaaacgat gaaaatgtcc tctgttcatc atcacagaaa aaaaggaacg
     5401 atgctcatga acaaaggaca gcgtcggatg caccgtttgc cgttttttgt tcaaatgaag
     5461 ggtatccata tgactgaagg cgtcaaaaag cgctttgccc agtccttcct tcatgtcttc
     5521 gatcacatcc tcaatgattg aaaacttatc ctcataataa aggtagagcg atccgcggct
     5581 cactttggcc ttctcagcga tttctttcat tgtgatgtgt tgaatatctc tatctttcaa
     5641 taaagccagc agcgcctctt tcacttgagc ttcggcagat tccggcacaa aagacacctc
     5701 caatcattag acagatctta gatatatgta cggtaacgta tagatggttc accgttgtct
     5761 ttcttacaga aaaggtacca ccttataata ggtccgagaa aagaagaaag caaatgaggg
     5821 ggattttaca atggaacagc aagtaaagga cgacatccag cgtgtctttc agcttcagaa
     5881 aaaacagcaa aaagccttgc gcgcttcaac agcggaacag cggagagaaa agcttcaacg
     5941 ctttttagat tccgtcatcg cccatgaaga agaaatcatc gaagcgatcc gcaaagacgt
     6001 ccgcaaacca tatcacgaag tcaaaaaagc ggaaatcgaa ggaacaaaaa aagcgattag
     6061 agataatatg aataacctgg aacaatggat ggcgcctaaa gaagtcggtt catcgttaag
     6121 ccctgacgca aacggaattc ttatgtacga gcctaaaggc gtcacactca tcctcggccc
     6181 gtggaactat ccgtttatgc tgacgatggc gccgcttgcc gcttctctcg cagccggaaa
     6241 cagcgcgatt gtgaagctgt ccgatttcac gatgaacacg agcaacattg ctgctaaagt
     6301 aataagagac gcttttgatg aaaaagaagt cgcgattttt gaaggagagg ttgaggtggc
     6361 aaccgaacta cttgatcagc cgttcgacca tattttcttc actggaagca caaatgtcgg
     6421 gaaaattgtc atgacagcgg ctgccaaaca cttggcatct gtcacacttg agcttggcgg
     6481 caagagcccg acgatcattg acagtgaata cgatctgatg gacgcagcga aaaagatcgc
     6541 cgtcgggaaa ttcgtaaacg ccggccaaac ctgcatcgca cctgattacc tgttcattaa
     6601 aaaagacgtt caggacaggt tcgcggggat tttacaaaca gtcgtcaacg ctggatttat
     6661 ggaggatgat cataccccag accgcagcaa atttacgcag atcgtcaatg accgcaactt
     6721 caaccgcgtc aaagatctgt tcgacgatgc catcgaaaga ggggcggaag tggtgttcgg
     6781 cggcgtattc gatgccagcg accgcacgat ctcgccaacc gttttgaaaa acgtcacgcc
     6841 tgacatgaaa atcatgcagg aggaaatctt cgcatcgatc ctgccaatga tgaactatga
     6901 agacatcgac gaggtcatcg attacgtaaa tgaccgcgat aaaccgcttg cactttatgt
     6961 gttcagcaaa aaccaagatc tgattgacaa cgtccttcag cacacgacat caggaaatgc
     7021 cgccatcaat gatgtcgtcg tccatttcag tgacgtcaac ctgccattcg gcggcgtcaa
     7081 cacaagcgga atcggctcct atcatggggt atacggattc aaagagtttt ctcatgagaa
     7141 gggtgtattt attcaggccg ctgaataatc gcatgatcaa aaggcgcttc cttagaggag
     7201 cgccttttat tgtaactcct tgaccaaaag caattcatca cggataggta ttttattatc
     7261 tgccagtaaa ggaatttcgg gcttcatctt tctggccgtc tcgactgcat tcacaaatag
     7321 tcgatccaac cggtaccctc tcttctgata aaacgctaat gcatgaatat tatcattggt
     7381 tgtgatcagt tttatttgtt tgatatttct ctctctgcat gcttcctcgg ctttctctag
     7441 cagagctgtt ccgatccctt tattctcaat gacactatcc agcgaaatga tttcacaggc
     7501 atcttcttca aatatgtatg taataaggcc aacaatctgg ttatcatcgt tgagcattcc
     7561 ataaccatct aattcatcgc agttataaat accgctagaa ataaccattt gcggactgcc
     7621 ccagtgtttt tgaaaaaacg cggaaacaag atctttaggt acctggcatg tcggaataat
     7681 attcatattt tcctcctttt agctgaacaa aaataagaga attaacaacc tattttatgt
     7741 cattaatccc cttatctagt atttactaga acttataact tgtcaaaagc tgtctgaata
     7801 ccaattgcgt ggattgataa ggatcaaaat ctgaatcctg agattggaag atttgctctg
     7861 gggtcaatgt ctctgcgttc tctgataacg tttgaatcag actttccaaa tatccattta
     7921 actctgattt ggacgattca tgtagggatt gatgatttac agcgagttct ctaaatctgt
     7981 tatcactgat taattttttt cgaagagctg ctagcatcaa gtcaagccat gcaggctggc
     8041 caaatgtaat atttaaagct aacgttgctt gatcagattt ggtggagtgc cataaacctc
     8101 ttggcaaata cagcatggtt cccggtgtta aattaacgat ttctgcatct ggcagatcct
     8161 cttttggcgg atctcctttc caatatgact gtaaatcatc aggatagtaa ggagcctctg
     8221 ataaatcata gtgctgcatt ggattgctca cattttcatt cttggcaagc ttccatgttt
     8281 tctcaccttg aatttgaaaa atcaagttgg tgtaggcgtc aaaatgggct ttgaatcccc
     8341 cgccattttt cgccgcgtaa acaatggctt tggaagaagt acccgcaggc agtcttaatt
     8401 ccgctttgag tttttctatc caccttctga cttggggaat aaataggtcg gtgaaatcaa
     8461 actctaatgc agcccctttt tcataccact ctaaagcctc tgcaggtgac acaagaaatc
     8521 tgtctgtgat cccttcagat tcttcaatca cagcatcacc aacgaccatg actggattat
     8581 tgtagatagc caatacgttt tctagcgttc taaccttttc aaaccccggt atgcttgtaa
     8641 atctctccac ttctcctctg gctaccaaag gttttacagg ccaatattct tctaaaaact
     8701 cactcatcgt tacaggactg atgatagact ccaaaaccga ttcggttaca gcactcatat
     8761 tatccctccc aaaaaaagta acttcaccac aaagatataa catttttttc taaaagtaaa
     8821 tattgacaga attatcagag gattataata tttagttgtg cgtgatagcc tattttttta
     8881 caaggaagga gggaaaagga tgaaaaaggc ttataagaaa cctcgtcttt ttgaactgcg
     8941 ccgtgctgta gcagctggcg gccattaatc tcatatagca tttgacatct agtactctat
     9001 tttaggaggg atgctcaatg aaaaaagctt ataagaaacc tcgccttttt gaactgcgcc
     9061 gtgctgtagc agctggcggc cattaatctc atatagcatt tgacatctag tactctattt
     9121 taggagggat gctcaatgaa aaaagcttat aagaaacctc gcctttttga attgcgccgc
     9181 gctgtagcag ctggcggtca ttaatcttat ccaaaacgat taacgtttga ggctatcacg
     9241 ccaacttgat aaggaggatg ctgaagatga ttacggctga agaatgcaga acgtacaaag
     9301 aatttgttga tctttaccaa tcctatcttt accccttgct tggcgccaga ctgtcccgga
     9361 tgtattcccc caaaaacaaa gtcattatcg atatgggcac aggtccaggt tatttaagca
     9421 ttcagttggc taaaagaaca aatgcgcacg tgcatgctgt cgatattaac ccggccatgc
     9481 atgaaatcgc tcaagaagaa gctaaaaaaa gcggagtaag cagcctgatt tcatttgatt
     9541 tggaagatgt ccaccattta tcttacgctg accaatatgc tgacttcatc gtctcctact
     9601 cttgcctgca tcattgggaa gacgttgtta aaggacttaa agagtgctat agagttctgg
     9661 ctccgggcgg aaaaattgtc attttggata catttaatcc ccaaggaagc catttagaga
     9721 ttatgcgaaa acaaatcaaa gaaccggaat acttcaggtt tgtaagagag gcatttgaag
     9781 aaagttattc ctttgaagac attcaccagt ttgttcagga tgccggcatt cccaattatt
     9841 cattagaaac ctttcacttt ttaccggagg attttataga aagcttagat gagctggagg
     9901 atgctcccct gtgggaacaa aatgatcaaa gtactgatca tgaaattgag tctgtcacat
     9961 ggatgttaac gatagaaaaa gaaaaggaag gtgcattgta atgatcaatg aatcaactgt
    10021 tttatccaaa aatccagaaa tgccatcaag aaaatatttg aaaagcatta ttatagagcc
    10081 gggcatcact ttaaatgaaa tggcatcaga tatttataac catatcgacg gcaaggtcag
    10141 catacatgat atttgctcaa aaatcgtcaa tgaatatgat gttgattatc aaacctgctt
    10201 agaagattgt atggagctgt ttgagttgct tattgatcat gaagcaatca aagttaagca
    10261 gggggcatga gaattggaaa aacaaaaagt gcttgcttta ccagacgatg tacatgagct
    10321 gagtacacac cgttctaaat caatcgtaaa ttacatcatc actctgcttg cctttgccaa
    10381 aaaacaagga ttgactcatc aagatattgt aagctggatt cacgagcaat atgaggaaag
    10441 aggatattat gatgagtgga gacacattaa cagccaacaa ccagttggat catttgtgga
    10501 actctttata aaaggaagac gtttacttta tgacaaaatt gaattgtttg aaacagaaga
    10561 taaatatgtc gtaaataccc acacttggta tgaaaaagaa cctagtgagg ccttttttta
    10621 ttttgaaatt gatcccgaag aattttctgc gtacgcttcc attctcgcaa tcgaaaacgc
    10681 aaaacgtctc ggaattaaaa tcgatattgt aaaagaaaca gatgtagaga cagcttatat
    10741 ctataaacat caataacgct attgggaggg agacatatgt gcgggctcgc gggtattata
    10801 aatctggctg ctccccgttc tcaggaatgt acctttcata tattgaaagg catggcagat
    10861 gccatcagct ataggggacc ggatgatgaa caatatcata ttgattccaa agtcggcttt
    10921 gcatttcggc gattgtccat tcttgacctt gtaaatggac agcagccctt tttaaatgag
    10981 gatggatcaa tcgtcgttat ggtaaatgga gaaatttata actataaaga actgaaggct
    11041 tctttacaca atcatatgtt taaaacgaca tctgattgtg aagtaattgt tcatttatat
    11101 gaagaaaaag ggattggatt tgtagacgac atcatcggaa tgttttcaat agccatttgg
    11161 gacaaaaata aaaacaaagt atttttagtt cgtgaccgct ttgggattaa accgcttttt
    11221 tacacagagc taaaacacga gcttatattt gcctctgaaa taaaatccct attttctcat
    11281 cctcactgtc cccgccaatt taattggaaa gaagcactct cagacatttg gctaagcggg
    11341 gaagcagcca gtaatcataa agaaaccact tccttttttg taaacatcca aaatctcgat
    11401 gctggccatt atctcgaaat taatttgaca acaaatgaac gaaaaacagc aagctattgg
    11461 tctttacagg atattttgct caggcaaggc tatcgtgaga atctccatcc cgatgacctg
    11521 attgaaggat atagagaact gctggcagat tcagtccata gatgtttaca aagcgacgtt
    11581 gaagtcgggt tgtttcttag cggtggcatt gattcagctg cagtcgcaca ttttgctgca
    11641 gaaaaacagg atctccatac gtttacagta ttaagccaaa gtacatttac aaatgaagat
    11701 gcaaaatatg cccattggct ggctaaagat ttacaccttc caaatcatca ggttctctat
    11761 caattaggga acgatgagtt attacaacca gagtcatata aacatttgtt atggatctgt
    11821 gaaacaccgt tttgcggacc ggaacaatta tataagtttc atttacataa gtatgccaaa
    11881 gcgataaggc caaacctgaa agtcatgctg accggccagg gcagcgacga atttaacggc
    11941 ggttacagca cgacactttc accagccgag aacccaagtt gggaaggatt tattgaatcg
    12001 gtcaatacga tggagatgaa ccggctgcat cggctgcagg gaaatatctt tagagtgtgg
    12061 gaggagcatt ttggactttc tcctataaac ctttcttatt taaagagcaa tgattccagc
    12121 caagcagatc cttggcaatc gtatgtcctg acaaaatacc gtgatctgca aatgtataat
    12181 tgctggcatg aagatcggat cgccgcggct aatcatatcg aaaaccgtgt accgttcttg
    12241 gaccatcggc ttgttgaatg ggtttgcgga atacctgatg gactccgtaa agacttgtta
    12301 tgggataagt cggtattgcg aaaatcatta acaaatgagc tgcatacaag ctatacccac
    12361 cggccaaagg ttcctttttt ctatggtaag gacgtgagat atacacataa aatgatgttt
    12421 catcttctga agaaaaacaa ttatcagctt atagaggagg ccttctctca cagcgatgcc
    12481 tccagcataa tacaggttga acacattcat gccatcatga catatttgga ggatgatcct
    12541 gagtttacaa attttgaatt tttattaaga ctggtgaaca tgggactttt atcaaaaatg
    12601 actaaagaaa ccccttctgt tcaattagac ataaccagcc atttagaatc gataacaata
    12661 aaagactggc actcacagga aggtgatatt gccagtcgtt taaatatctc agccaataag
    12721 tgtgaaggac aagatatttt ggcgctaaac cctggcgtca ctctgttaag gccggaaagc
    12781 gatagtgagc attgcatcta cattgcggaa gaaggattta ttcagtttat tgtttcggag
    12841 gaagacgtcg gagcttggct gcatattctc tgcgatatta atggaaaaga cacacttcat
    12901 acgattttag acagacatgg tgtcagcctt gaagaagtgg ccaaatatat tcaagaagcc
    12961 atcgaacaca atatcatttt gatcaaacaa aaaaatctgc cagaaggagc atatagatga
    13021 gcatctttta ttcgttttcc gcacttaggg gattagcaat ggggattttt tcgcctattt
    13081 ggattcttta tctgatatct aaagattatg atttccttca gattggatta atgggagcgg
    13141 tacttgaaat tgctaagctt atatttgaag ttccttccgg cgtttttgct gatcgttatg
    13201 gaattaaaat ttcaattgcc agttcattct ttttctccat ccttacatgg gccttcttcc
    13261 cttttatcga ttcagctgct atttgcatac tggctatgat catatgggct ttatcagatt
    13321 ccttaatttc cggttctttt gaaacttgga tgagccgtgt cgcaggggaa gatcgattcg
    13381 gcaaagaaat gatgaaaaac acacaattgc taatcacttt tttaattatt ggaagtattg
    13441 ccagcgggta tttgtattca ttaaatatct attttccttt cctgctcgtt atggtgatct
    13501 acttattact atttatttgg atgtctgtat ttattaaagt cccttctgtt tccgaaacaa
    13561 atcatgggga tcagaaccaa catgattcga taaagattat caaagaaagt ttaaaaatta
    13621 tctttaacaa aaaaagggtt cttttaatcg tcatagccgg tttctttaca gccacagcct
    13681 atgacacaat ttcccgttac tggcagcctt ttttgagtga tttaggcttt tcagaaaagt
    13741 cactgggata tatttttgcc ctaggagggt ttaccgctct cgttcttttg acattaacca
    13801 tcaggttcga aaagaagatc gaaaaaaatc catatctcgc tttaacctca ttggattcca
    13861 tgggcatggt catgactttt ctattgtcta gagcattcag gccgctgggc attccatgta
    13921 cagcgttttt gcttgcaatt gaagatattc atcatccgat cgtaacaagt tacttaaata
    13981 agtttttccc cgattcatac aagaacacac ttttctcgtt aaactcaggg gtaggagcaa
    14041 ttggagaaat tctttccggt gtcattttcg gcatcatttc cgcagccttt gggctctctg
    14101 ccatgtttgt tgttgtagct gtatttctat taatccctat tatcctttat acgatagtgc
    14161 ctaagattaa agacaatgat atgaaagttc agattgaaaa atcccagcaa gtgtaaatgt
    14221 tttgtatcac agtaagaaga ccttcttatt aaaagaaggt cttctgctat tctattcagt
    14281 tatttcccaa aagccatcag cttcgtataa cttccaatat aaagtgttcc gtcctcagcg
    14341 agctgaggag aagacacgac gttgctgtcg gtttgatagc tccataattc attgccgttt
    14401 gcgtctgccg cataaacctt catatcatct gacccgaaat aaaccgttcc cttcgcgtca
    14461 atcagcggcg ccgttctgac agggccgtct gtgtagaatg accagttcat atccccgttt
    14521 ttgctgatgg aaaacagctc gccgcttcct gagccgatgt agatattgcc attatgatca
    14581 atcgcaggag atgagctgga gaacccgttt agcgggaatg tccatttcaa actgcctgtt
    14641 gatgtataag catacagctg tccatcttgg ttgccggcat aaatgtttcc gtccttatca
    14701 atcaccggat atcctttaaa cgcatttgac gtcgttctgg accatttcac ctgtccggtt
    14761 ccggagttga tcgcataaaa cacgtaatta tatgtgccga catacacggt gccgtttttg
    14821 gcaagcaccg gcacagagct gacgacccca tttgttttca acttccagcg ctctgtccag
    14881 gttgattttg acgtcggttt gatcgcgtga acataattat caagtgttga gaaatacaac
    14941 gtcccgtctg aaccgatcac cgtttcagag cttggcccgc cgcttaacgg aaccgttgtt
    15001 aaaatttctc ccgtttcttt gtcaataaaa taaatctttt tgtcatagga tgccaaatag
    15061 ataacgccgt tggtcccaag tacaggagat tgcgtatatg tttttccaag attgcccgtc
    15121 acccatttga ctgagccgtc tggattaaag gctttcattt ccccgtctct ggaatgaaga
    15181 tatactgtgc cgtctccgtc aatcacagcc cccgctccat tttgcggagt cgttctgatg
    15241 tcgttttgcc atttcagcgt cccgtctgta tttccggcga accggctttc gcgtgaccag
    15301 ttaaacatgg caggcgccat cgcttgtaca tcatatcttc ctggcaaaaa gccagatgct
    15361 ccattatttt gagaaaacac cgtttccgcc gcataagcag ctgtcggctg aagcactttg
    15421 gcagcgggca catcagaaac agcgccggcc gaaacagccg ccgccaccgc agctcccgca
    15481 atcaaagctt tcatacgaaa tgacttgacc atcattgaga cccccattat atgtaacttc
    15541 taatttgtga ccatcataac atattcatcc attttataaa tctatttcac aaaaacatca
    15601 caaactagaa aactatgtaa gagtattcac ggacgttttt tcagcacccg atcgaaatgc
    15661 agccacaaac caaatgacgt tgacagcagc cgcagcgaga ctaactccca aaacaaagat
    15721 cacctcagaa agcagatggt cactaaagaa actaaacatc aagataaaac cggccgaaga
    15781 caaatgaatc aaaagcccga agccgcaaag caccgccatg acatacctca ttgcatcgac
    15841 tccgagcata taaacgagaa atggaatgaa atacaagaca aggatcatac cgacagctga
    15901 ccacatgcca gctgaattaa actgattggc cgccgctccc gttccggcca gcggcgaaag
    15961 tgaagccgcc acaatcacgg cgcaaaaaag aaacgcagaa atggttgtca tgatcgccac
    16021 gctatttttt tttgacatca aactcctcct ttaatagaaa tattaacctt ttttattata
    16081 agtaagttga atgttatatt cattatattt ttaaaaaatt ccagaataca tacacaaatg
    16141 ctatgcttct ttctagtata tttatatagt aaaaaacaaa ggataaaaga ctcatttttc
    16201 tgtaatatca ggattttatc accataccat attgcatgta catgtttttc aaagtatact
    16261 attccagatt aattcagagg agagagaaaa atacatggaa aaaccagcag gattttggat
    16321 tcgtttttta gcttatttta ttgacggcat tattgtatct gttcctagtt atattattct
    16381 atttattatc aattctgtgt ttgtagctgg ggctgtggca acaaaccctt acatgacgga
    16441 agaagagtat ttagtgaaat acatgacgct tgcatttttg cctactatgc tgatcatgat
    16501 cgtcatcagc gtgttatatt acgggctgct cacagcttct aaaatgcaag gcacacttgg
    16561 caaaaaaatt cttggcctga aagtggtcaa tgaacaaggt gaacgggttt ctgtcggaca
    16621 gggaattggc cgttactttg cctatatctt atctggaatc atcttttata tcgggtttat
    16681 catgatcgcc tttggagaga aaaaaggcct gcatgacatc atttgcaaaa cacgtgtcgt
    16741 gtataaataa tagaaaaaag tctagacgcc aataggcatc tagacttttg ttttctttgc
    16801 aataggctgc cacgacagat acgtagcgct tctccacaac cactcaaacg gccccatccg
    16861 aaagacacga agccaaaggt ggctgaagac catttgaacg gcacaaacag caattgtaat
    16921 gagcacaccg gcagcagggt acacttttcc atacaggccc aagccgtaat gataaaaaat
    16981 ccaagtacac acaatagact gcatcaaata attggtaaat gccatcctcc caacagcgga
    17041 gaatgattgc agcactgttc tcactcttgt tttatgataa agatagacaa ccgttgtaac
    17101 atagaaaaac atgaggaaag gcgcgccaat cagcaaacat atttctttat ccgttacact
    17161 gtacagcacc tgggcgccga tgccgatgac aagcccagcc atccataatc gttttaatcc
    17221 tttgcgatgc ttttccggtt catgcaaata ccgtgatttt gctgccgcag ctcccagcaa
    17281 aaacatgctg aaatatggaa tggatgcaaa gaagtagttg agcggattat acgtaagcat
    17341 gccattcgaa gacatgtaaa caagacggtc gtggatccgc tgttctgcaa tatccttcag
    17401 gctgccgctt ccataaacat gaatcgcttg ttttgcctgc tgtgttaccg cttgtaccca
    17461 ttcctgtccg tttgattgat caaaacttgt caacatgaac ggaatggaaa acagaagata
    17521 caaagagacc gcccatatca gcagtgtttt cggctttgct tttcgaaaca agagcaggac
    17581 aaatccgagc agggcatatt ctgttaaaat atccccgtcc catatcaaaa aggcatgaat
    17641 cgttccaaac aagagaagcg ccattaacct tctcacatat aacggaacaa accgtttccc
    17701 tttgttttct gctctctcca tcatgacaac catgccaaat ccaaataaaa aggaaaacaa
    17761 taaaatacat tttgtttgaa tgaagaattt cagtatgtct gcggcggcaa aatcagcttc
    17821 agaccactta tccatgaaaa aattctcttt tccaagcata gacaaataca tatccggata
    17881 actgaaatgt gccagattga caaataagat gccgaaaatc gccattcctc tcagcacatc
    17941 aagcacaccg atccgctcat ttgttaaagt cggctgtaat gaagacatag ccatcacgct
    18001 ccttttttct gtaccttaag ggtaggaaaa aatgaagcgc ggtaacatcg atttaggtgt
    18061 caggccggca tgaaaacctt acaatcttgt catctttatg gtttcatcac ctttaaatct
    18121 aatgcttcga tattctgcaa aatgcgatca aagcgcaaag cctgaggctc acatgggaag
    18181 atgtggcctt catacgggtc gcctaacgtc cggaaaaacg gttcaaataa accaggaacc
    18241 aatacgccca ccatctttgt atagtgagaa tcaaggcgat aggagtgaac ggtatttgca
    18301 gggacatgca ggaaatctcc cggattcagc tgaatttcct ggccatctgt ccacatcgtc
    18361 atctggcctt caaggcaata aaatgtttct gtatgatatt catggtagtg atcaacgatt
    18421 cggtcacctt tagggccttc agatgatacg acgataaact ggccatctgt atttttttgt
    18481 gcagccacaa tgcggtgaag ctgatctcca gtcaacagac gatctccttc tccagattca
    18541 agaacgtatg gaaccgctcc atctggcagc tctgtaagtt ccgctaattt ggccgaacat
    18601 gcaggctttg cttcatctag aaatacaatg tccgctacag cggctgcttc tgcaaatcgc
    18661 tcgtttgaga cttcttcgct tgcgtacggc ggatgttcag cgtgatcata cggattccca
    18721 ataacggaat acaagtgcgc tacgtttcct ttcatcgtgt aagacaccag tcttgttctg
    18781 tggctctgca tccggtagct gtgcggtgtt cccgccggaa tgttggcata atcacctgat
    18841 attaataaat agcgttcacc atcaagtgtc agttccagtt tcccgtccaa aacgagaatt
    18901 ccttcatgtg tgtccttgtg gacgtgaagc ggaaaggcat ctccttttcc cccggaaaga
    18961 agcacgatct caaacaaatc acctgtgctc ctcccattcg ccatcaccgt ggcaacctgt
    19021 ctgccgaaca gatagcgctc gccttctccg ctccggagca aataaggcat tttttcttta
    19081 ggcaatgaat gtgtacataa tgttttcata ttatcgcttc ctccaattta gaccagtcta
    19141 tatattatca ttcatttgtc tagaccgttc tatataattg taggagaaag gataacaaaa
    19201 tgctaccctt tttttctcac cagcactggt atttgttcgg caatgagaag aagaggcgtt
    19261 ttgtctttat tcgttaacga aagcatgatg ccgccctcaa tcatcgaatt aatcagcgtt
    19321 ccaagctgat ttgcttcttc ttctgcaaat ccgttttcca ttaattttct ggcaaaaacc
    19381 gcttcccagc ttttaaacac cttcatgcaa accgtccgca gcggttcact gattaacgct
    19441 gtctcactcg ccagcaaacc gactggaata cctttaatgc tttctgtgtt gtcaaattgg
    19501 ctggctgttt ttttgataaa aagctgaatc gcttcaacag gatcagagga ttcatccatg
    19561 ctttgctgta tcagatgttc aacgatctta cctgtatatg taaccgcttc aattgctagt
    19621 tcttctttgc cattcggaaa aaagtgataa agcgatcctt ttggagcacc gctttctttt
    19681 acaatctggt tcaaacctgt cgcgtgatat ccttgcagct ggaacagacg tgacgccgtg
    19741 tgaaggattt tttcacgtga atctcctctg ctagtcatta aaacattccc tcctaggtat
    19801 ggtagagcga cttatataat ataaaaaaga accctgtgat tgtcaaaagg ggtaagaccc
    19861 ttccggatgg ggtaatgtac aaaaacagcg tctaggaggg atctctcaat gacaatcgat
    19921 cattcagtca caaatacaga gcagcttgaa caacagaacc ccgccataaa aacaaagctc
    19981 aaactgaaaa agcttaagga tcaggtgatc gtcattaccg gcgcttcaag cggtatcgga
    20041 cttgtcacgg cgagaatggc agctgaaaaa ggcgcaaagg tcgtggcagc agcgcgaaat
    20101 gaagaggcgc tgaaggagct cactgatgaa cttaaggaaa aagggcacga cgccatatgg
    20161 gtaaaggcgg atgtcggaaa agaagaggac gtcaaccgca tcgcagaaac cgcgatcagc
    20221 acattcggcc gctttgatac atgggtcaac aatgcggccg tctcgacttt
//
