LOCUS       c00076_NZ_CBYM..        3220 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CBYM010000076.1 Clostridium saudiense strain JCC, whole genome
            shotgun sequence.
ACCESSION   NZ_CBYM010000076
VERSION     NZ_CBYM010000076
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 15:31:18
            Original ID  :: NZ_CBYM010000076.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 3220
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..3220
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[25:589](+)"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      26..589
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..3220
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..3220
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="1"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             26..589
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg76_1"
                     /sec_met_domain="AgrB (E-value: 8e-35, bitscore: 108.0,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKRIVNVIINGLSRSVSYSQEQREHIEYSLTVITYELIKLILIV
                     LILYMLGLLKEGLAVLLAIIITKPFIGGYHEDSQIKCFFATMTIVCGLIILGRSIELNM
                     VSIIILNIFSIFCIYHRAPVINEKMPLTKEKLIRRNRKIGLVNVSLLAMLSIISYKSTV
                     YGELICLTNVVQTMLMFNKYKRKE"
     PFAM_domain     50..556
                     /aSDomain="AgrB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04647.17"
                     /description="Accessory gene regulator B"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg76_1_0001"
                     /evalue="4.40E-31"
                     /label="ctg76_1"
                     /locus_tag="ctg76_1"
                     /protein_end="177"
                     /protein_start="8"
                     /score="107.8"
                     /tool="antismash"
                     /translation="IINGLSRSVSYSQEQREHIEYSLTVITYELIKLILIVLILYMLGL
                     LKEGLAVLLAIIITKPFIGGYHEDSQIKCFFATMTIVCGLIILGRSIELNMVSIIILNI
                     FSIFCIYHRAPVINEKMPLTKEKLIRRNRKIGLVNVSLLAMLSIISYKSTVYGELICLT
                     NVVQTM"
     CDS             595..717
                     /locus_tag="ctg76_2"
                     /transl_table=11
                     /translation="MKRIVASCLLFVSTLLVNSGTASILTIGVEEMPDSIKKLR"
     CDS             730..1986
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 66; E-value: 5.7e-20)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg76_3"
                     /transl_table=11
                     /translation="VIINIADSISSLLQSMALIYISNYCTKKIYQKSSKDLIAMVVILW
                     AIVEITTGLVGNSSLGTIFIHLVMLISLIIIFKKDPLGAMIGFGIVYISIAINLIICSN
                     IYLGYLQYIFLDKYPELGMIIFMYLPQYIMAILMLYNKNFIKKIYKVIRSRNISIIAIV
                     IVTIVMDFLVSFSAIVHDRDNPLFKEFVFISFSIFIVLLTLYFFNIEKKAKEILNVNFA
                     LEEMNNELKKVKHDYGAQISYLYGLHLMGQHERLGSALKDIINNNSNVASEIEIINGSD
                     SVMAAIVNGIEHKGINIILDDQIDFEDSCISEVEFQRVISNILRNAVNVMNGTGVIQIK
                     SYYNMNHIIVKIKNNGPKIKEDIIDKIFDVGFSTKENSKKENGFGLSIVKEIIEGANGT
                     IGVSSDDDFTEFTINIPKL"
     PFAM_domain     1666..1977
                     /aSDomain="HATPase_c"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02518.28"
                     /description="Histidine kinase-, DNA gyrase B-, and
                     HSP90-like ATPase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg76_3_0002"
                     /evalue="5.50E-16"
                     /label="ctg76_3"
                     /locus_tag="ctg76_3"
                     /protein_end="416"
                     /protein_start="312"
                     /score="59.2"
                     /tool="antismash"
                     /translation="EVEFQRVISNILRNAVNVMNGTGVIQIKSYYNMNHIIVKIKNNGP
                     KIKEDIIDKIFDVGFSTKENSKKENGFGLSIVKEIIEGANGTIGVSSDDDFTEFTINIP
                     "
     CDS             2316..3164
                     /locus_tag="ctg76_4"
                     /transl_table=11
                     /translation="MAIIKINEFIRGVKHMKRVIKRVTKVFTVSFLLINTFILPVNSEN
                     VDLFKVKLEEIGIPEEYSKNISDHIENLDISAEEFQAIMNNSSEVFSRIEEGQEISDFS
                     LSDLVGIYSEALRVANDLDIEVKIDSNNKEVEIKDKENDEILLKCHIEDVKKYYENYKK
                     SPLTDEEYDDLLKYIDSSDDSISNNNEDSSVSEKKDTNENSINNDMNEDDTNIDKVEVS
                     DASNTIVNDSESNSSINKADTISQKNRYRVLSIIYLVLLLCVLLSIVSSKLFKEKDEKW
                     Q"
ORIGIN
        1 gtagaaagtt aagttggggt atttaatggt aaagagaata gtaaacgtaa ttataaacgg
       61 tttatcaaga agtgtaagtt atagtcaaga gcaaagggag catattgaat atagtttgac
      121 tgtaataact tatgaattaa taaagcttat tttgatagtt ttaattttat atatgttagg
      181 acttttaaaa gaaggactag ctgtattatt agcaataata ataactaaac catttattgg
      241 tggatatcat gaagatagtc agataaaatg tttttttgca acaatgacaa tagtatgtgg
      301 cttgattata ttaggaagaa gtattgaatt aaatatggta tctattatta tattgaatat
      361 atttagtata ttttgtatat atcatagagc tccagtaatt aatgaaaaaa tgccattaac
      421 aaaagaaaag cttataagaa gaaatcggaa aataggttta gttaatgtat ctttattggc
      481 aatgctatca attattagtt ataaaagtac agtatatggt gagcttatat gtcttactaa
      541 tgttgtacaa acgatgctaa tgtttaataa atataaaaga aaggagtgat tataatgaaa
      601 agaatagtag caagttgttt attatttgta tctacattat tagtaaattc agggacagca
      661 tcaatattaa ctataggtgt ggaagaaatg ccagattcta taaaaaaatt aaggtaggtt
      721 ttgacagaag tgattatcaa tatagcagac tcaattagta gtttattaca aagtatggct
      781 ttaatttata tttcaaatta ttgtactaaa aaaatatatc aaaaaagttc aaaagattta
      841 atagcaatgg tagtaatttt atgggctata gttgaaatta caactggact tgtaggaaat
      901 tcgagtttag gaacaatatt catacattta gtaatgttaa tttcactgat aataatattt
      961 aaaaaggacc cattaggagc aatgataggg tttgggatag tatatatatc tatagcaata
     1021 aatttaataa tatgttctaa tatttattta ggatatttac aatacatatt tttagataaa
     1081 tatcccgaat taggtatgat aatatttatg tatctaccac aatatataat ggctatttta
     1141 atgttatata ataagaattt cataaagaaa atttataagg taataagaag taggaatata
     1201 tcaataatag caatagttat tgtaactata gttatggatt ttttagtatc gtttagtgcg
     1261 atagtgcatg atagagataa tccattattt aaagagtttg tatttataag tttttctatc
     1321 tttattgttc tacttacttt atacttcttt aatatagaaa agaaagcaaa agaaatatta
     1381 aatgtaaact ttgctttaga agaaatgaat aacgaattaa aaaaagttaa acatgattat
     1441 ggagcacaga tatcatattt atatggacta cacttaatgg gacaacatga aagattaggg
     1501 tctgctttaa aagatataat caataacaat agtaatgtag catcagaaat tgaaataata
     1561 aatggttctg attctgttat ggcggctatt gttaatggga tagaacataa aggaataaat
     1621 attatattag atgatcaaat tgattttgaa gatagttgta tttcagaagt agagtttcaa
     1681 agagtaattt ctaatatatt aagaaatgct gttaatgtaa tgaatggaac tggagtaata
     1741 caaattaagt catattataa tatgaatcat ataattgtaa aaataaaaaa taatggccca
     1801 aagataaaag aagatataat agataagata tttgatgttg gtttttcaac aaaagagaat
     1861 agcaaaaaag aaaatggatt tggactttca attgtaaaag aaattattga aggggctaat
     1921 ggaactatag gtgtatcaag tgatgatgat tttaccgaat tcactataaa tatacctaaa
     1981 ctttagacga gcatatttta atacatattg ccattaattc aaggttttaa tattgacttt
     2041 acttaattat tggcattcaa aaaatgttct aaataaaagt ataaattaat tattaaataa
     2101 tgaggactct cataactaat ttttatatgt tatgggagtc cttaaatttt aaaagcttga
     2161 gatttattta aattaaaagc agcatcaaat taaaaaacaa caagtatact ttaatcatca
     2221 acaaaacatt tagaagaagt ggatttaatt aaatagggat aattggactt tttaagctct
     2281 aagcatttat acgataaagt ttatttttat gatttatggc aataatcaaa ataaatgaat
     2341 ttataagagg agttaaacac atgaagagag tgattaaaag agtaactaaa gtgtttactg
     2401 ttagtttttt attaataaat acatttatat tgccggtaaa tagtgaaaat gttgatttat
     2461 ttaaagtaaa gcttgaagaa ataggaattc cagaagagta ttcaaaaaat attagtgatc
     2521 acatagaaaa cttagatatt agtgctgaag agtttcaagc aataatgaat aatagtagtg
     2581 aagtgttttc taggattgaa gaaggtcaag aaataagtga tttttcttta tcagaccttg
     2641 ttggaatata tagtgaagca ttaagagttg caaatgattt agatattgaa gttaagattg
     2701 attcaaataa taaggaagta gagattaagg ataaagaaaa tgatgagata ttactaaaat
     2761 gccatattga agatgtaaaa aaatattatg agaattataa aaaatcacca ctcacagatg
     2821 aagagtatga tgatttattg aagtatatag atagtagtga tgatagtata tcaaataata
     2881 atgaagattc atcagtttca gaaaaaaaag atacaaatga aaatagtata aataatgata
     2941 tgaatgaaga tgatacaaat atagataaag ttgaagtaag tgatgctagt aatactatag
     3001 taaatgattc tgaaagtaat agttcgatta ataaagctga tacgattagt cagaagaata
     3061 gatatagagt attaagtatt atttatttgg ttttattgtt atgtgtgctt ttatcaatag
     3121 tgagtagtaa gttatttaaa gagaaagatg aaaaatggca ataaatagga tatagccttt
     3181 ttaggcaaag aatgaattta aatattataa cgaaaagggg
//
