LOCUS       c00012_NZ_NKAQ..       20267 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_NKAQ01000002.1 Priestia megaterium strain 22-2
            22-2_R1_(paired)_contig_2, whole genome shotgun sequence.
ACCESSION   NZ_NKAQ01000002
VERSION     NZ_NKAQ01000002
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 14:23:43
            Original ID  :: NZ_NKAQ01000002.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 386062
            Orig. end    :: 406329
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..20267
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[396062:396329](-)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10267)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..20267
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..20267
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(148..831)
                     /locus_tag="ctg12_371"
                     /transl_table=11
                     /translation="MKKRTKTIIAVIAGAAILIGGIWMINESRYPNVPAFDDHFTREFL
                     NKDKKVDDGFYEFKSKTGQYTMWFPEEYQLLHENEQQYVRDGDFYERWKASSVKNKEEN
                     QLNYLQVKLSESNPDDESIYVESLFKDEFGVNNPQKWETANTRIYFDTGYLYFKGTEEH
                     VIYDKNKHAPNTYIAYVADKNSSKVIELWFDDSLNNQVGRESDKKDWFVKVLNSIHFKE
                     GKKHE"
     CDS             complement(1090..1479)
                     /locus_tag="ctg12_372"
                     /transl_table=11
                     /translation="MISEKRSLLLKEQAKLLALKEYKGIVKSISLSKILTLPIYIVDIL
                     TLNGEEHKVKINAQTGSILKEKTIPLTKSRAKAYALRQHKGIIESVVLANKQYEIVILG
                     LDGKTHSVKIDAEIDVLAQEERNVQ"
     PFAM_domain     complement(1282..1449)
                     /aSDomain="PepSY"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03413.21"
                     /description="Peptidase propeptide and YPEB domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_372_0001"
                     /evalue="2.00E-05"
                     /label="ctg12_372"
                     /locus_tag="ctg12_372"
                     /protein_end="66"
                     /protein_start="10"
                     /score="25.1"
                     /tool="antismash"
                     /translation="KEQAKLLALKEYKGIVKSISLSKILTLPIYIVDILTLNGEEHKVK
                     INAQTGSILKE"
     CDS             complement(2097..3077)
                     /NRPS_PKS="Domain: NAD_binding_4 (5-166). E-value: 3.5e-13.
                     Score: 41.0. Matches aSDomain:
                     nrpspksdomains_ctg12_373_NAD_binding_4.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score:
                     260.5; E-value: 3.8e-79)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_373"
                     /sec_met_domain="NAD_binding_4 (E-value: 5e-12, bitscore:
                     41.0, seeds: 102, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 4.6e-17,
                     bitscore: 57.6, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="RmlD_sub_bind (E-value: 2.9e-16, bitscore:
                     55.0, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MILVIGGAGYIGSHLVKELVKTNEVVVLDNLSTGHRWAIDEKAVF
                     VEGNLGNEKDLESVFTNHKIDAVMHFAANSLVGESVTDPLKYYQNNVAATLTLLQTMMK
                     HNVKKFIFSSTAATYGIPSVDIITEDTATNPINPYGRSKLMIEQILADFASAYDMEYVV
                     LRYFNAAGAYETAEIGECHDPETHLIPIILQHLLGERENISVFGSDYDTEDGTCIRDYI
                     HVTDLANAHISALQALLDGTKKTATYNLGNGLGYSVKEVIETCEKVTGKKANVVMADRR
                     AGDPARLVASSDKIHAELGWKAQISLEKIIASAWNWHQNSAKVTN"
     aSDomain        complement(2112..3077)
                     /aSDomain="TIGR01179"
                     /aSTool="tigrfam"
                     /description="galE: UDP-glucose 4-epimerase GalE"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg12_373_0001"
                     /evalue="9.20E-136"
                     /identifier="TIGR01179"
                     /label="ctg12_373"
                     /locus_tag="ctg12_373"
                     /protein_end="322"
                     /protein_start="0"
                     /score="450.0"
                     /tool="antismash"
                     /translation="MILVIGGAGYIGSHLVKELVKTNEVVVLDNLSTGHRWAIDEKAVF
                     VEGNLGNEKDLESVFTNHKIDAVMHFAANSLVGESVTDPLKYYQNNVAATLTLLQTMMK
                     HNVKKFIFSSTAATYGIPSVDIITEDTATNPINPYGRSKLMIEQILADFASAYDMEYVV
                     LRYFNAAGAYETAEIGECHDPETHLIPIILQHLLGERENISVFGSDYDTEDGTCIRDYI
                     HVTDLANAHISALQALLDGTKKTATYNLGNGLGYSVKEVIETCEKVTGKKANVVMADRR
                     AGDPARLVASSDKIHAELGWKAQISLEKIIASAWNWHQNSA"
     PFAM_domain     complement(2325..3074)
                     /aSDomain="Epimerase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01370.23"
                     /description="NAD dependent epimerase/dehydratase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_373_0002"
                     /evalue="3.70E-59"
                     /label="ctg12_373"
                     /locus_tag="ctg12_373"
                     /protein_end="251"
                     /protein_start="1"
                     /score="200.2"
                     /tool="antismash"
                     /translation="ILVIGGAGYIGSHLVKELVKTNEVVVLDNLSTGHRWAIDEKAVFV
                     EGNLGNEKDLESVFTNHKIDAVMHFAANSLVGESVTDPLKYYQNNVAATLTLLQTMMKH
                     NVKKFIFSSTAATYGIPSVDIITEDTATNPINPYGRSKLMIEQILADFASAYDMEYVVL
                     RYFNAAGAYETAEIGECHDPETHLIPIILQHLLGERENISVFGSDYDTEDGTCIRDYIH
                     VTDLANAHISALQALLDGTKKTATYNLG"
     aSDomain        complement(2580..3062)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg12_373_NAD_binding_4.1"
                     /evalue="3.50E-13"
                     /label="ctg12_373_NAD_binding_4.1"
                     /locus_tag="ctg12_373"
                     /protein_end="166"
                     /protein_start="5"
                     /score="41.0"
                     /tool="antismash"
                     /translation="GGAGYIGSHLVKELVKTNEVVVLDNLSTGHRWAIDEKAVFVEGNL
                     GNEKDLESVFTNHKIDAVMHFAANSLVGESVTDPLKYYQNNVAATLTLLQTMMKHNVKK
                     FIFSSTAATYGIPSVDIITEDTATNPINPYGRSKLMIEQILADFASAYDMEYVVLRY"
     CDS_motif       complement(3015..3071)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_373_0001"
                     /evalue="1.80E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg12_373"
                     /protein_end="21"
                     /protein_start="2"
                     /score="11.0"
                     /tool="antismash"
                     /translation="LVIGGAGYIGSHLVKELVK"
     CDS             complement(3276..4160)
                     /locus_tag="ctg12_374"
                     /transl_table=11
                     /translation="MKLVNIIEQGKEQAAILDNDSILLIEDINTKYLTNWSTTIWDLIQ
                     YKELRHLETWYAHNKFGMNSSFPLLHLQGRKTAPIISNPSKLLGIGFNYAASEEKLKDY
                     DRAIDPVSFLKPATAIIGPDDSIRIPKQSYKTTAEAELAVVIGETCKDIEPDEAINVIA
                     GYTSAIDVTAADIHAANHRYLMRAKSFDTFCSIGSEFITKESISNVKSLQVRTLLNGNV
                     QHENTVSNMIYDIAYCVSFFSKVMTLHPGDIILTGTPGPAVIEDGDCIECQIEGMLPLK
                     NKVKDMKKVPQQI"
     PFAM_domain     complement(3309..3893)
                     /aSDomain="FAA_hydrolase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01557.20"
                     /description="Fumarylacetoacetate (FAA) hydrolase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_374_0003"
                     /evalue="3.30E-47"
                     /label="ctg12_374"
                     /locus_tag="ctg12_374"
                     /protein_end="284"
                     /protein_start="89"
                     /score="161.2"
                     /tool="antismash"
                     /translation="IGFNYAASEEKLKDYDRAIDPVSFLKPATAIIGPDDSIRIPKQSY
                     KTTAEAELAVVIGETCKDIEPDEAINVIAGYTSAIDVTAADIHAANHRYLMRAKSFDTF
                     CSIGSEFITKESISNVKSLQVRTLLNGNVQHENTVSNMIYDIAYCVSFFSKVMTLHPGD
                     IILTGTPGPAVIEDGDCIECQIEGMLPLKNKV"
     CDS             complement(4157..5356)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1105:amidase (Score: 265.6; E-value: 1.4e-80)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_375"
                     /transl_table=11
                     /translation="MKDTWNAFVDSDLYVPPTGTGMLNNLSFALKDVFDVQGHISSAGN
                     PDWLATHQPASEHADVVAALLKEGAVLKGVTHTDELMYGLNGENAHYGTPINPKSADRI
                     PGGSSSGSAVAVAAGITDFAIGTDTGGSVRIPSSYCGIFGYRPSHGRISTNGLIPLAPS
                     FDTVGVMARDGHTLQKVGAVLLNSTSRASGFTRLYVPTDVMELVDEQSMRALAPSINHV
                     MESFSTIEEIAIAPQGFSTYMETFRLLQGKEIWQTHGEWIQKENPTFGEDIGSRFQWAS
                     TLTLLNMNYIEEKRRELRYFMYSQLGEEGILVLPTAPGPAPVKDAKGLELENRRLRTLQ
                     MTCIAGLSGLPQVTIPAGELDGLPIGLSFIAGYNQDEKLLNWVKENSDRIIQASVRSVS
                     "
     PFAM_domain     complement(4217..4486)
                     /aSDomain="Amidase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01425.23"
                     /description="Amidase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_375_0005"
                     /evalue="1.30E-07"
                     /label="ctg12_375"
                     /locus_tag="ctg12_375"
                     /protein_end="380"
                     /protein_start="290"
                     /score="31.1"
                     /tool="antismash"
                     /translation="IEEKRRELRYFMYSQLGEEGILVLPTAPGPAPVKDAKGLELENRR
                     LRTLQMTCIAGLSGLPQVTIPAGELDGLPIGLSFIAGYNQDEKLL"
     PFAM_domain     complement(4766..5299)
                     /aSDomain="Amidase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01425.23"
                     /description="Amidase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_375_0004"
                     /evalue="2.70E-54"
                     /label="ctg12_375"
                     /locus_tag="ctg12_375"
                     /protein_end="197"
                     /protein_start="19"
                     /score="185.0"
                     /tool="antismash"
                     /translation="TGMLNNLSFALKDVFDVQGHISSAGNPDWLATHQPASEHADVVAA
                     LLKEGAVLKGVTHTDELMYGLNGENAHYGTPINPKSADRIPGGSSSGSAVAVAAGITDF
                     AIGTDTGGSVRIPSSYCGIFGYRPSHGRISTNGLIPLAPSFDTVGVMARDGHTLQKVGA
                     VLLNSTSRASGFTRL"
     CDS             5560..6270
                     /locus_tag="ctg12_376"
                     /transl_table=11
                     /translation="MEQSTTLFLFILLAFVLTRGIPFIGSLAPSINTLLRHIGRYFSNL
                     NTMFHEDGHALMGLIVGKGVNRIELYTNNEGVAVTATYAGSRGWLPRVIIALAGYPFSS
                     AMAYLFFYLLVHHHYDWLFYGLGSVVVINLLLWVRNGYGIVWLFSIGLILGGIYYLQDP
                     QLMRYSMMFVGALLLVESLFSAFIIFVLSIKYPNDAGDATSLKQLTHLSARFWGLLFFA
                     QAVYVAYLIFQLIY"
     PFAM_domain     5662..6246
                     /aSDomain="Peptidase_M50B"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13398.8"
                     /description="Peptidase M50B-like"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_376_0006"
                     /evalue="4.90E-37"
                     /label="ctg12_376"
                     /locus_tag="ctg12_376"
                     /protein_end="229"
                     /protein_start="34"
                     /score="127.6"
                     /tool="antismash"
                     /translation="LRHIGRYFSNLNTMFHEDGHALMGLIVGKGVNRIELYTNNEGVAV
                     TATYAGSRGWLPRVIIALAGYPFSSAMAYLFFYLLVHHHYDWLFYGLGSVVVINLLLWV
                     RNGYGIVWLFSIGLILGGIYYLQDPQLMRYSMMFVGALLLVESLFSAFIIFVLSIKYPN
                     DAGDATSLKQLTHLSARFWGLLFFAQAVYVAY"
     CDS             complement(6578..7705)
                     /locus_tag="ctg12_377"
                     /transl_table=11
                     /translation="MLIEFIQSLYDQSRPLPENQDDYTSILEDIEYFHLSATVYSLLKQ
                     QGRMEQTPTYFQNQLKTEYQAVLYNNLYIKNQLKLILDTFETNGISAIPLKGIMFAETY
                     FGHFSARRTTDIDILICKEDMEKAIECIQELEYDTEGECPAHHFHRSFSKSIPHSPVPL
                     AIELHWDLLRENSSALEIEQFWQHSSPLADYKHIKQLSEVHTFYMICLHGWKHGMDSLK
                     YFIDIIQAIHVLNHKIDYDALFKIAKNDHTLKRLTSTLTVVYNQFPHLDQINSLPFNKK
                     SKIWWNYQDIRCGDRQSVKGFKNLIRVHLSEYDQFKHSMVFFKRWFFPDKFEITNLYPP
                     SIKHKKYSIFRGYIKFYRKKFHTLFRALFYSKVKS"
     PFAM_domain     complement(6923..7630)
                     /aSDomain="NTP_transf_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14907.8"
                     /description="Uncharacterised nucleotidyltransferase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_377_0007"
                     /evalue="4.30E-40"
                     /label="ctg12_377"
                     /locus_tag="ctg12_377"
                     /protein_end="261"
                     /protein_start="25"
                     /score="137.9"
                     /tool="antismash"
                     /translation="ILEDIEYFHLSATVYSLLKQQGRMEQTPTYFQNQLKTEYQAVLYN
                     NLYIKNQLKLILDTFETNGISAIPLKGIMFAETYFGHFSARRTTDIDILICKEDMEKAI
                     ECIQELEYDTEGECPAHHFHRSFSKSIPHSPVPLAIELHWDLLRENSSALEIEQFWQHS
                     SPLADYKHIKQLSEVHTFYMICLHGWKHGMDSLKYFIDIIQAIHVLNHKIDYDALFKIA
                     KNDHTLKRLTSTLT"
     CDS             complement(7734..9536)
                     /gene_functions="resistance (resist) ABC_efflux (Score:
                     263.1; E-value: 3.2e-80)"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 341.3; E-value:
                     1.8e-103)"
                     /gene_kind="transport"
                     /locus_tag="ctg12_378"
                     /transl_table=11
                     /translation="MKLNRADIKRYFDKEEMISAFSIVYPLLRKHWKAYAGLMLFLLTD
                     ILITLASAWFLGDLSDAAVQGDFTRVKHLLPFAFGLILISFLTIYYDTYIEAVATSSIK
                     RDLKEQLLRQLLLSPVHKIHTTHSGEFISHFTNDINSIDGMIGRNLINLIKLPLLFIAI
                     FLYLAHISLLLSFVGLFIIPIAVIAGGVFGFLLRNSSREILKLNSEMTSSLSEIFQGFI
                     VIRSFLLERSFFSKYRQQNQQALALDLYNGKMKGLFYAGGEAIALIAFLVTLCFGALIV
                     SKGMLTVGSLLAFVSLSNRLIYPLNGLAGQWAAFQRSISAIERIAPILKAQYETTDFPE
                     FSQNKPKQKAICFQNMTFSYDGERYIFENFNLQIPAGKSIAIVGASGAGKSTLFNLLQG
                     FYKPQAGKIYVDQTPLDGLTASELQNLIAYVPQETFLFTGTIRENLLLANPQTTEEELV
                     IAARAAHIHDFILSLPHGYETKIGEKGITLSGGQKQRVAIARAILKNAPILLLDEATSA
                     LDNETEYLVKEALQGIMKNRTTIVIAHRLSTIQNVDSIIVIDKGKLIQLGKHEELIHQP
                     GLYRDLAHVNTLQLSNNEERAIML"
     PFAM_domain     complement(7989..8435)
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_378_0009"
                     /evalue="1.00E-34"
                     /label="ctg12_378"
                     /locus_tag="ctg12_378"
                     /protein_end="516"
                     /protein_start="367"
                     /score="120.1"
                     /tool="antismash"
                     /translation="ENFNLQIPAGKSIAIVGASGAGKSTLFNLLQGFYKPQAGKIYVDQ
                     TPLDGLTASELQNLIAYVPQETFLFTGTIRENLLLANPQTTEEELVIAARAAHIHDFIL
                     SLPHGYETKIGEKGITLSGGQKQRVAIARAILKNAPILLLDEATS"
     PFAM_domain     complement(8625..9422)
                     /aSDomain="ABC_membrane"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00664.25"
                     /description="ABC transporter transmembrane region"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_378_0008"
                     /evalue="1.00E-33"
                     /label="ctg12_378"
                     /locus_tag="ctg12_378"
                     /protein_end="304"
                     /protein_start="38"
                     /score="117.3"
                     /tool="antismash"
                     /translation="MLFLLTDILITLASAWFLGDLSDAAVQGDFTRVKHLLPFAFGLIL
                     ISFLTIYYDTYIEAVATSSIKRDLKEQLLRQLLLSPVHKIHTTHSGEFISHFTNDINSI
                     DGMIGRNLINLIKLPLLFIAIFLYLAHISLLLSFVGLFIIPIAVIAGGVFGFLLRNSSR
                     EILKLNSEMTSSLSEIFQGFIVIRSFLLERSFFSKYRQQNQQALALDLYNGKMKGLFYA
                     GGEAIALIAFLVTLCFGALIVSKGMLTVGSLLAFVSLSNRLIYP"
     CDS             complement(9565..10011)
                     /locus_tag="ctg12_379"
                     /transl_table=11
                     /translation="MPINQESVVLLKNVIEKKGYVHFPSEGFSMYPCIRQNDLCTFEKA
                     PVLKKGDIGLFHTKSGQLIAHRLIKTRYKNEQLHYIFKGDTNLYCDEPVTREQVIGKLT
                     AISRKKQKKVYMAAPFDYIWCWLMLFFPFSSRFLKKYINQKIVN"
     CDS             complement(10001..10267)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_380"
                     /sec_met_domain="PF05402 (E-value: 2.4e-09, bitscore: 33.0,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 9.1e-13,
                     bitscore: 43.7, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQFIRNQDMEAVQLDSEWVILNTEAYTVTKINELGGCCWSLLEN
                     PCTIPSLIRSLQTDYRIEDELSFEDMESFLSELIKYGLIDYAN"
     PFAM_domain     complement(10016..10216)
                     /aSDomain="PqqD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05402.14"
                     /description="Coenzyme PQQ synthesis protein D (PqqD)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_380_0010"
                     /evalue="7.80E-08"
                     /label="ctg12_380"
                     /locus_tag="ctg12_380"
                     /protein_end="84"
                     /protein_start="17"
                     /score="32.6"
                     /tool="antismash"
                     /translation="EWVILNTEAYTVTKINELGGCCWSLLENPCTIPSLIRSLQTDYRI
                     EDELSFEDMESFLSELIKYGLI"
     CDS             complement(10267..11049)
                     /locus_tag="ctg12_381"
                     /transl_table=11
                     /translation="MEKVTIRIGEHQALIVCHSFQILSLIQKNYEPFFAEIERPDMVIR
                     IEDGYGVPFVDYQVDVEQKADTISFQRADYRIQANLSKGEAHIQIYDELALKHALMNFY
                     SSYIVYHNWGLLIHSSCATEKGKAHLFAGQSGAGKSTCAKLSAPRPILSDEATLLKVEK
                     NQITVFNSPFRSELSAPSIKGTIPLASIQLLHQSLNNERTKLGKASALLQIMDKVFYWN
                     KDREETKKIVQMIKEVLDYVPVYDLYFQKNNTFWELIS"
     CDS             complement(11204..11380)
                     /locus_tag="ctg12_382"
                     /transl_table=11
                     /translation="MKMTKKQPGVSPKRPMVMDHQPIRFETAQSWNPGQGNQDHPGHGN
                     GGVNFPPNNPNRP"
     CDS             12206..12919
                     /locus_tag="ctg12_383"
                     /transl_table=11
                     /translation="LSLFLKWKQKKQEKEAERVLEESISKRKDYWNTIGHVDGDVLTHL
                     LNPMFFGGPAWPSGRQTFIRVQKTETVILASDGLSDPFQSPEEKSRKQGKGLEFYIECD
                     DESLRGPLSDIQDHWAFDLLYQMSQNAAAHPNMLELFMKHDILSIEFTDLDVPSHFVNE
                     NGEIGVLLGVQSPSVSASLSLPYESIKLISMKLLTPNELEYVREQGAQGRRQLAETFQL
                     SKSYHITLTKRESLI"
     PFAM_domain     12407..12904
                     /aSDomain="SUFU"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05076.15"
                     /description="Suppressor of fused protein (SUFU)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_383_0011"
                     /evalue="3.40E-06"
                     /label="ctg12_383"
                     /locus_tag="ctg12_383"
                     /protein_end="233"
                     /protein_start="67"
                     /score="27.2"
                     /tool="antismash"
                     /translation="KTETVILASDGLSDPFQSPEEKSRKQGKGLEFYIECDDESLRGPL
                     SDIQDHWAFDLLYQMSQNAAAHPNMLELFMKHDILSIEFTDLDVPSHFVNENGEIGVLL
                     GVQSPSVSASLSLPYESIKLISMKLLTPNELEYVREQGAQGRRQLAETFQLSKSYHITL
                     TKR"
     CDS             13105..14037
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039:aldo/keto reductase family oxidoreductase (Score:
                     303.2; E-value: 3.1e-92)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_384"
                     /transl_table=11
                     /translation="MAEKVQIGKSELYVNPIGLGTNAVGGHNLYPNLNEEVGKDLVHKA
                     LDNGINLLDTAFIYGPKRSEELIGEVLKERGNREEAVIATKGAHKIVGDEVLLDNSPAF
                     LKQSVEDSLKRLQTDYIDLYYIHFPDKNTPKDEAVGALKELKDEGKIRSIGVSNFSLDQ
                     LKEANKDGYVDVVQGQYNLIQREAENDILPYTAANRISFIPYFPLAAGLLAGKYDKNTK
                     FNDLREDMPHFIGEAFQQNLEKVERLRQISSAKGVEVAHLVLAWYLTRDSIDVLIPGAK
                     RADQVLDNLKTLDVQLTSSEIKDIDHIFK"
     PFAM_domain     13150..14028
                     /aSDomain="Aldo_ket_red"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00248.23"
                     /description="Aldo/keto reductase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_384_0012"
                     /evalue="4.50E-74"
                     /label="ctg12_384"
                     /locus_tag="ctg12_384"
                     /protein_end="308"
                     /protein_start="15"
                     /score="249.2"
                     /tool="antismash"
                     /translation="PIGLGTNAVGGHNLYPNLNEEVGKDLVHKALDNGINLLDTAFIYG
                     PKRSEELIGEVLKERGNREEAVIATKGAHKIVGDEVLLDNSPAFLKQSVEDSLKRLQTD
                     YIDLYYIHFPDKNTPKDEAVGALKELKDEGKIRSIGVSNFSLDQLKEANKDGYVDVVQG
                     QYNLIQREAENDILPYTAANRISFIPYFPLAAGLLAGKYDKNTKFNDLREDMPHFIGEA
                     FQQNLEKVERLRQISSAKGVEVAHLVLAWYLTRDSIDVLIPGAKRADQVLDNLKTLDVQ
                     LTSSEIKDIDHI"
     CDS             complement(14075..14428)
                     /locus_tag="ctg12_385"
                     /transl_table=11
                     /translation="MYILIMLVAAAVLVDFILRKVLDIPRSKFWGKYEYESLALGRWDK
                     YVTIAFVLFLVLDMIFMFVEPYIVSCLFLVAAILLKGIDEWKYKQETKEYITSFVQMGF
                     FLTAFVLLTSGIV"
     PFAM_domain     complement(14093..14395)
                     /aSDomain="DUF4181"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13789.8"
                     /description="Domain of unknown function (DUF4181)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_385_0013"
                     /evalue="2.70E-16"
                     /label="ctg12_385"
                     /locus_tag="ctg12_385"
                     /protein_end="112"
                     /protein_start="11"
                     /score="59.9"
                     /tool="antismash"
                     /translation="VLVDFILRKVLDIPRSKFWGKYEYESLALGRWDKYVTIAFVLFLV
                     LDMIFMFVEPYIVSCLFLVAAILLKGIDEWKYKQETKEYITSFVQMGFFLTAFVLL"
     CDS             complement(14461..15330)
                     /gene_functions="regulatory (smcogs) SMCOG1014:LysR family
                     transcriptional regulator (Score: 135.7; E-value: 3.1e-41)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg12_386"
                     /transl_table=11
                     /translation="MEIKWLKTFIIAASYENFRQASEDLFLTQPAVSKHIQRLQQELGD
                     ELFEKKGKYIVLTEAGRFFLPHAQKMVRAYEEGVGNFRLWKQGYNRKLTISAAPQIAAS
                     VLPSLIKQFVERYPHIEVTVNITNSFQVGKDISDRRSDIGLTRMLPGQADVSYELIHKE
                     KAVLVAPFSAGARTEQELLSSYRLLTNNHPVYWEDLLLQIKACYPHIQLLPVTQVEITK
                     RFIEEGLGVSYLPFSMVKKEVENQTLSVISQQKIIRPSSHTYIVTKGETEETKQFKHFV
                     AETLTETS"
     PFAM_domain     complement(14482..15072)
                     /aSDomain="LysR_substrate"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03466.22"
                     /description="LysR substrate binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_386_0015"
                     /evalue="3.00E-25"
                     /label="ctg12_386"
                     /locus_tag="ctg12_386"
                     /protein_end="283"
                     /protein_start="86"
                     /score="88.9"
                     /tool="antismash"
                     /translation="QGYNRKLTISAAPQIAASVLPSLIKQFVERYPHIEVTVNITNSFQ
                     VGKDISDRRSDIGLTRMLPGQADVSYELIHKEKAVLVAPFSAGARTEQELLSSYRLLTN
                     NHPVYWEDLLLQIKACYPHIQLLPVTQVEITKRFIEEGLGVSYLPFSMVKKEVENQTLS
                     VISQQKIIRPSSHTYIVTKGETEETKQFKHFVAE"
     PFAM_domain     complement(15145..15321)
                     /aSDomain="HTH_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00126.29"
                     /description="Bacterial regulatory helix-turn-helix
                     protein, lysR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_386_0014"
                     /evalue="5.70E-17"
                     /label="ctg12_386"
                     /locus_tag="ctg12_386"
                     /protein_end="62"
                     /protein_start="3"
                     /score="61.5"
                     /tool="antismash"
                     /translation="KWLKTFIIAASYENFRQASEDLFLTQPAVSKHIQRLQQELGDELF
                     EKKGKYIVLTEAGR"
     CDS             15462..16136
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 77.5; E-value:
                     1.8e-23)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_387"
                     /transl_table=11
                     /translation="MKNNVKEKFNAHASQYDEQRRKLIPCFFDFYSIPVSLLHFPKKTL
                     RILDMGAGTGLFSSFVKEKYPDAHFTLIDVSDQMLEKAKERFKNEQHIEFIVSDITSYK
                     FEHSFDIVISSLAIHHLEDEQKQKLYEQIYDLLHTGGIFINADQVLGPSSIIEELYKKD
                     WSERIAASGLTHEQIEAAHERTKLDKMATLHDQLNWLTASGFSTVDCIYKFFNFVVMYA
                     QK"
     PFAM_domain     15603..15893
                     /aSDomain="Methyltransf_11"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08241.14"
                     /description="Methyltransferase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_387_0016"
                     /evalue="4.50E-18"
                     /label="ctg12_387"
                     /locus_tag="ctg12_387"
                     /protein_end="144"
                     /protein_start="47"
                     /score="65.8"
                     /tool="antismash"
                     /translation="LDMGAGTGLFSSFVKEKYPDAHFTLIDVSDQMLEKAKERFKNEQH
                     IEFIVSDITSYKFEHSFDIVISSLAIHHLEDEQKQKLYEQIYDLLHTGGIFI"
     CDS             16706..17764
                     /locus_tag="ctg12_388"
                     /transl_table=11
                     /translation="MANRISRTAIVLIAAILALACLFVGVPKTEAASTPSHLIIINKAT
                     NKLAYYQNGSLVRTFSVGTGRTQSLTPEGHFKVVNKIVNRPYYKGNIPGGDPRNPLGNR
                     WLGLNARGTYGTTYAIHGNNNPASIGKYVSSGCVRMYDEEVEWLFSKVTVGTPVVITTS
                     SKSFNDIAAANGYNVSGNSGSTPAPSTGTVLKKGSKGNAVKELQQKLTSLGYNAQGTDG
                     VFGANTDSAVRKFQKDHGLTADGIVGPSTYKALGSSGTNPTTPTNPTNPKPTNPPADTT
                     INTKQTLKKGSKGSNVQALQKKLTAIGYNTKGTDGIFGANTEAAVRNFQKDNKLAADGI
                     AGPNTLTAISKR"
     PFAM_domain     16814..17185
                     /aSDomain="YkuD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03734.16"
                     /description="L,D-transpeptidase catalytic domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_388_0017"
                     /evalue="1.60E-24"
                     /label="ctg12_388"
                     /locus_tag="ctg12_388"
                     /protein_end="160"
                     /protein_start="36"
                     /score="87.1"
                     /tool="antismash"
                     /translation="HLIIINKATNKLAYYQNGSLVRTFSVGTGRTQSLTPEGHFKVVNK
                     IVNRPYYKGNIPGGDPRNPLGNRWLGLNARGTYGTTYAIHGNNNPASIGKYVSSGCVRM
                     YDEEVEWLFSKVTVGTPVVI"
     PFAM_domain     17303..17470
                     /aSDomain="PG_binding_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01471.20"
                     /description="Putative peptidoglycan binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_388_0018"
                     /evalue="6.30E-20"
                     /label="ctg12_388"
                     /locus_tag="ctg12_388"
                     /protein_end="255"
                     /protein_start="199"
                     /score="71.2"
                     /tool="antismash"
                     /translation="GNAVKELQQKLTSLGYNAQGTDGVFGANTDSAVRKFQKDHGLTAD
                     GIVGPSTYKAL"
     PFAM_domain     17585..17752
                     /aSDomain="PG_binding_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01471.20"
                     /description="Putative peptidoglycan binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_388_0019"
                     /evalue="4.00E-18"
                     /label="ctg12_388"
                     /locus_tag="ctg12_388"
                     /protein_end="349"
                     /protein_start="293"
                     /score="65.5"
                     /tool="antismash"
                     /translation="GSNVQALQKKLTAIGYNTKGTDGIFGANTEAAVRNFQKDNKLAAD
                     GIAGPNTLTAI"
     CDS             complement(17831..19762)
                     /locus_tag="ctg12_389"
                     /transl_table=11
                     /translation="MKVFRAKACQSPMRKGWSIMFQHPFKKDERGRSNPFVKRFMYTEQ
                     HDEIDILVEEMNELLRVQDFWTSTAKGRAKARYDERVVNAFYNDIEKRTSEQIDSEYEY
                     VHVIGEQGSGKTSLIRQLLGIKKECGFLGIGSKGAYSATYKVKDSQHYEAAVSFFTRSE
                     VQRKLENILLRSAEVYAEGGTDYDLVFELLHGDSSFNLRALLGDIPYKARYFNDDVPLR
                     MNDENSSFKQFVDAIKRESEIVKDAVDQEGRDFAEGWHKRLECRKITEQMLLAIESRLK
                     EYKEGTWEIGEDDWPISCRLTAKELSSLGPLTNEEEENNGRLIYPLFRRIEVCGPFSFK
                     KGLAICEHPYFEYTSTIHDSFKKAASILYVHHGLKELDIQFLQQLIVHGHGAKVNVCVT
                     HGDLLTSPSCRTDYAKKHAMAKMIDGALKSVSPLMKKQLHYYLTVGNTTILECVHEEFK
                     ESHLLYKDLKAALVSETRKKQQELHPIYLNLTVSQAFYEAMESLNIPYMDRETCLNISL
                     GEHEGPVPVITSAFISSVYEHFLSQPSGWSSTYHSVTDRQQVIQELAGEFATVVYSYFN
                     EQLLEKSRNDWLALYKQKEDDQAYKYSRLIENVIPAKNDIYQQQILMRTVYHLIKYVVE
                     KKDGVLVH"
ORIGIN
        1 tctgagctac tataaatttc aaaattagga atttctctcc ctgtatgttt tttgtatatc
       61 tctttaattt ctttttcttt attagataag tttttatatt caagttgagt tattttattt
      121 cttaaactat catctaaaat gcatttatca ttcatgcttc tttccctctt taaaatgaat
      181 actattcagt acttttacaa accaatcttt tttgtcagat tccctaccaa cttgattatt
      241 tagactgtca tcgaaccata attctattac tttactagaa ttcttatctg ctacgtatgc
      301 tatatatgta ttgggagcat gtttattttt atcatagata acatgttctt ctgttccctt
      361 aaaataaaga tatcctgtat caaagtatat acgtgtatta gctgtttccc acttttgagg
      421 attatttact ccaaactcat ctttaaataa actctccacg taaatagatt catcatcagg
      481 attgctctct gataacttta cttgtaaata gttcaactga ttttcttctt tattcttaac
      541 tgatgaagct ttccatcttt cataaaaatc tccatccctt acatactgtt gctcattttc
      601 atgtaacaac tgatactcct ccggaaacca catcgtatac tgcccggtct tcgacttaaa
      661 ttcataaaac ccatcgtcca cttttttatc tttgtttaag aattcacgcg taaagtgatc
      721 atcaaaagca gggacgtttg ggtatcggct ttcgtttatc atccatattc ctcctattaa
      781 aatagcagct cctgcaatga ctgcaataat ggtcttcgta cgttttttca ttgtcgcaca
      841 cccttttagt tatgttataa cctatgtttt atacatgttc gatactatca tacttataat
      901 gggagagtca taagcagaac gaatcaaaga accataatta ggaagtggtt attttttact
      961 atcacttacc ctttctttta gataagtaat cgtttctttt ttattatttg ttacctttgc
     1021 tacaggtttc tccaaataaa gaaaacccca ctttcaacaa agtgaggttg attacataat
     1081 ataagacgtt tactgaacgt ttcgctcttc ttgcgccagc acatcaattt cagcgtcaat
     1141 cttcacgctg tgggtttttc catcaagtcc aagaatcaca atttcatatt gcttgttagc
     1201 aagaacaacc gattcaataa tgcctttatg ctgtcttaac gcgtatgctt ttgcacggct
     1261 tttggttaaa ggaatcgttt tttctttcaa aatactgccg gtttgggcgt taatttttac
     1321 tttatgctct tctccgttta acgtaaggat gtctactata taaataggaa gagtgagtat
     1381 tttactcagc gatatggatt tgacaatgcc tttatattct tttaatgcga gaagctttgc
     1441 ttgttctttc aacaaaagtg atcgtttttc agaaatcatt tgacgccatc ctttctagtt
     1501 tataaaacgg actgctgttt caatttctta acgtaccata tcctatgtat acgtctacta
     1561 actagtatag cgggcttgtc ttaaatttct cttaatatta catgaaagat agctgaagaa
     1621 agctgttatt cactgaaaaa actagacctg gttagatcta gcttcttatt tgtgaatgtg
     1681 aattctacat ttttttcgtt tcgaatcgtt ctacggctct catttgtttg attgacgggg
     1741 atttgtgtac gcacatgccc agatgaactt tttgaagcaa atagggatca atgtaaaaac
     1801 cattttgaaa gatgttttct ttttcctgtt cgtcatgaaa tttggagcat cttacacagt
     1861 aatacatatc ataacctcct tgcggactat tttataaacg ggatagttgt gaatggtata
     1921 tttacctaca tcatatggaa aagaacaaaa gtcgtgcttg tttagggaaa atgtccgaaa
     1981 aggagaaggc ttgtccatgg gctaaaccac tggcttttca aaatgattat ttagaacata
     2041 aatcagtttg attgtaacaa aaaagcctct ttcaaaaaga aaagaggcac tttttattaa
     2101 tttgttactt ttgcgctgtt ttgatgccag ttccaagctg atgcgatgat tttttctaat
     2161 gaaatttgcg ctttccagcc taattctgcg tggattttat cagaagatgc aactaggcgt
     2221 gccggatctc cagcgcggcg gtctgccata acgacattcg cttttttacc ggttactttt
     2281 tcacacgttt cgatcacttc ttttacagag tagccaaggc cgtttccaag attgtacgtt
     2341 gctgttttct tcgtgccgtc taacagggct tgaagcgctg agatatgagc attcgctagg
     2401 tccgttacgt gaatgtagtc acggatgcac gttccgtctt cagtatcgta gtctgaaccg
     2461 aatacagaga tgttttcacg ttcaccaagc aggtgctgaa gaatgattgg aattaagtgc
     2521 gtttcaggat catggcactc accaatttct gctgtttcgt aagcacccgc tgcgttgaag
     2581 taacgaagca ccacatattc catatcgtaa gcacttgcaa agtcagctaa aatctgttca
     2641 atcattaact ttgaacgtcc gtacggatta attgggtttg ttgccgtatc ttctgtaatg
     2701 atatctacag aaggaatccc atatgtagca gcagtagatg aaaaaataaa ctttttcaca
     2761 ttgtgcttca tcatcgtttg taaaagggtt aacgtcgcag ctacgttgtt ttgataatat
     2821 ttaagaggat ctgttactga ctcccctact aaactattag cagcaaaatg catgacagca
     2881 tcaattttat gatttgtgaa tacgctttct aaatctttct cattacctag atttccttct
     2941 acgaataccg ctttttcatc gattgcccag cgatgacccg ttgatagatt atcaagtacc
     3001 acaacttcat ttgttttcac taattctttt actaggtggc ttccgatata gcctgctcct
     3061 ccgatgacta aaatcatact gtcagtcagc tcctttttat taagtgtcgc tacagatatc
     3121 gtacccgttt cttttccatt tgtaaatatt tcatttttca gtatatgata acgcaaatgc
     3181 tatcttttaa ttagtatatc tactaattgt gaactgagtg tgaagatatt cgtttctact
     3241 taaaaacccg cgcgtgtaag caacgggttt tcttcttaga tttgctgagg cactttcttc
     3301 atatctttta ctttattttt taatggaagc atcccttcaa tctgacattc aatacagtcc
     3361 ccgtcttcaa taacagccgg tcccggcgtt ccggtgagga tgatatcacc tggatgcagc
     3421 gtcatgactt ttgagaaaaa tgaaacacag tatgcgatgt cgtaaatcat attagacact
     3481 gtattttcat gctgtacgtt tccgtttagc aatgtgcgca cttgaagtga tttcacgttt
     3541 gatatacttt cttttgtgat aaattctgag cctatactgc aaaatgtatc aaagcttttc
     3601 gctcgcatta agtagcgatg attcgccgca tgaatatcag ctgcggttac gtcaattgct
     3661 gacgtataac cagcaattac gtttatggct tcatctggct ctatatcctt acacgtttcg
     3721 ccgattacca ccgctagttc tgcttcagcc gttgttttgt aggactgctt tggaatacga
     3781 atgctgtcat ctggtccaat aatggcggtc gcgggtttta aaaaactaac tggatcaatg
     3841 gcacggtcgt agtcttttag tttttcttca gaagccgcat aattaaaccc aatgcctaat
     3901 aatttcgacg gattactaat gataggagct gtttttctgc cctgcaagtg cagtaaggga
     3961 aaagagctgt tcataccaaa tttattatgg gcataccatg tttcaaggtg gcgaagttct
     4021 ttatattgaa taagatccca aattgttgta gaccagtttg ttaaatattt agtattgata
     4081 tcttctataa gcagaatgct gtcattgtct aaaatggctg cttgttcttt cccttgctct
     4141 attatattta ctaacttcat gatacgctcc ttaccgatgc ttgaatgata cgatcgctgt
     4201 tttcttttac ccaatttaat aatttttcat cttggttgta tcctgcaata aaagataaac
     4261 cgattggcaa accgtctagt tctcctgcag gtatcgtaac ttgaggaaga ccgcttaggc
     4321 cggcaataca cgtcatttga agtgttcgca atcttctgtt ttctaactcc agcccttttg
     4381 catcttttac aggcgctggt cctggagctg taggaagtac taatattcct tcttccccaa
     4441 gctgtgagta cataaaatag cgaagttcac gacgcttttc ttctatataa ttcatattta
     4501 ataatgtaag agtgctggcc cattgaaagc ggcttccgat gtcttctcca aacgttggat
     4561 tttctttttg aatccactct ccgtgcgttt gccagatttc ttttccttgc agcagacgga
     4621 aggtttccat atatgtagaa aaaccctgag gagcaatcgc tatctcttct atagtagaga
     4681 aagactccat tacgtggttg atagacggcg caagagctcg catgctttgt tcatccacaa
     4741 gttccatcac atctgttggt acatacagcc gtgtaaatcc actagcacgc gacgttgaat
     4801 tcaataaaac cgctcctact ttttgcagag tgtggccgtc tctagccatt acaccaactg
     4861 tatcaaagct tggagcaagt ggaatcagac cgtttgtaga aatgcgtccg tgagaaggac
     4921 gatacccaaa aataccgcag tagcttgaag gaattcgaac cgatcctccc gtatctgttc
     4981 caattgcaaa atcagttatt cccgctgcca cagcaaccgc tgatccgctc gaagatcctc
     5041 ccggaattcg atctgcgctt tttggattta taggtgttcc gtaatgtgca ttttcaccat
     5101 ttagtccgta cataagctcg tcggtgtgcg taactccctt cagtacagct ccttctttta
     5161 aaagagcagc tactacgtct gcatgttcgc ttgcaggctg atgcgtggcg agccaatccg
     5221 gatttcctgc acttgatata tgtccttgta catcaaatac gtcttttaac gcaaaactca
     5281 agttatttaa cattcccgtt cccgttggag gtacgtaaag atcactgtct acaaatgcgt
     5341 tccacgtatc tttcattcaa ccatctcctc atttcttata tctgtttaga atataaaatt
     5401 tggaataagc tggtcaatga atgtgtcagg tctgttaaca ttaatattat gtagatctcc
     5461 cagcttccct ttccctagag aaactagccg ttttatttcc cttttagcac gtttgcgagt
     5521 aaagtagaaa catatcattt tacgaaaagg actatcgcga tggaacaatc tactacgctt
     5581 tttttattta ttttattagc ttttgtgcta acaagaggta ttccatttat aggttcactt
     5641 gctcctagca ttaatacact gcttcggcat attggacgtt atttttcaaa tttaaatacg
     5701 atgtttcatg aagatggcca cgcgttaatg gggcttattg tcggaaaagg cgtcaatcgc
     5761 attgagcttt ataccaataa tgaaggtgta gctgtgactg ccacctacgc gggatcccgt
     5821 ggatggctgc cgcgcgtcat tattgcttta gccggctacc cgttcagctc agcaatggct
     5881 tatttgtttt tctacctgct cgttcaccat cactacgact ggctttttta cgggctagga
     5941 agtgttgttg ttattaattt actgctttgg gtacgtaatg gatacggaat tgtgtggctt
     6001 ttttctatcg gtttgatcct cggaggcatc tattatctgc aagatccaca gcttatgcgc
     6061 tacagtatga tgtttgttgg tgcgctgttg cttgtagaat ctctattttc tgcatttatt
     6121 atctttgtat taagcattaa atatccaaac gatgcaggtg acgctacgag tttaaagcag
     6181 ctgacccatc tttcagcacg cttttggggt ttgttattct tcgcacaggc cgtgtatgtg
     6241 gcttatttga tttttcaact catttattag agaaagacgc agcggaaaca atataatcaa
     6301 tactccacaa ccttgtatat ttaaacaaag aatgcttctc gttttatgag atagcattct
     6361 ttatttacgt tttccttgca atgaattttt acctaaaagc accttcataa aagtaacctg
     6421 acttttttga tgtttttgtc taaaccaaaa aagcaccttc taattaaaaa gacgctttat
     6481 tatagctacc tctttaaagt tttaatcaac gatcattgaa tgtcttgtaa aattaccaaa
     6541 aaacacgttt aactatatta atcttttaat atttttgcta acttttaact tttgaataaa
     6601 ataaagcacg aaataatgta tgaaactttt tccgataaaa tttaatatac cctctaaaga
     6661 tactatattt tttatgtttt attgaaggtg gataaagatt agttatctca aacttatctg
     6721 gaaaaaacca cctcttaaaa aagaccatag aatgcttaaa ctggtcatat tcagacaaat
     6781 gtacccgaat aagattttta aatcctttta cgctttgtct gtccccacaa cgtatgtctt
     6841 gataattcca ccatattttt gattttttat taaaaggaag gctattaatt tgatcgagat
     6901 gtggaaattg attataaaca actgttaatg tgcttgttag tcgttttaaa gtgtgatcgt
     6961 tttttgctat tttaaataac gcatcgtaat caattttatg attcaagaca tgtatagctt
     7021 gtataatatc gataaaatat tttaaagaat ccattccatg cttccagccg tgaagacaaa
     7081 tcatataaaa ggtatgtact tcagacagtt gttttatatg tttataatct gctaacgggc
     7141 tagaatgctg ccagaattgc tcgatttcta acgcggaact attctctctt agaagatccc
     7201 aatgaagttc aatagctaat ggaacaggag aatgagggat cgatttacta aacgaacgat
     7261 gaaagtgatg agctgggcat tccccttctg tatcatattc taactcttga atacactcta
     7321 tcgctttttc catatcctct ttgcagatta atatatcaat gtccgttgtc cttcttgcac
     7381 tgaaatgacc gaaatatgtt tcagcaaaca taattccttt taatggaatg gcagagatac
     7441 cgttagtttc gaacgtatcc aaaataagct ttagctgatt tttaatataa aggttgttat
     7501 acaaaacagc ttgatattct gtctttagct gattttgaaa atatgttggc gtttgctcca
     7561 ttctcccttg ctgctttaac agagaatata ccgttgctga taagtgaaag tattcgatat
     7621 cttctaatat agaggtgtaa tcatcctgat tttctggcaa tggacggctt tgatcatata
     7681 atgattgaat aaattcaatg agcattatgg aaatcctcct agtttatttg tctttacaac
     7741 atgattgctc tttcttcgtt attagaaagc tgtagtgtgt tgacatgagc aaggtctcgg
     7801 tataagcctg gctgatgaat cagctcttca tgctttccca attgaatcag ttttccttta
     7861 tcaatgacaa taatagaatc aacattttga atggtagata acctatgagc aattacaata
     7921 gttgtcctat ttttcataat tccttgaagt gcttctttaa ctaagtattc tgtttcattg
     7981 tctaatgcag atgttgcttc atcaagcaat agaataggtg cattctttaa gatagctcga
     8041 gcaattgcaa ccctctgctt ttgccctcca gataatgtta tccctttttc gcctattttg
     8101 gtttcatacc catgaggaag tgacaaaatg aaatcatgaa tatgagcagc ccttgcggct
     8161 atgactagct cttcttcagt tgtctgagga ttggctaaaa gcagattttc tcttatagta
     8221 ccggtaaaaa gaaaggtttc ctgtgggaca tatgcaatta agttctgcag ttcggatgca
     8281 gtaagaccat caagcggtgt ttgatctaca taaatttttc ctgcttgagg cttataaaaa
     8341 ccttgtaaca agttgaatag agtagatttt cctgcaccgc tcgctcctac gatagctatg
     8401 ctttttcctg caggtatttg taaattgaaa ttttcaaaga tatacctttc tccgtcatag
     8461 ctaaaggtca tattctgaaa acaaatagct ttttgttttg gcttattttg agaaaactca
     8521 ggaaaatcag tagtttcata ttgcgctttt aatataggag ctattcgttc aattgctgat
     8581 atagaccgtt gaaatgcagc ccactgtcct gcgagtccat tcaatggata aatcagccgg
     8641 ttgctgagac ttacaaacgc tagaagggaa cccactgtta acatcccttt tgaaacgatt
     8701 aaagcgccga agcagagagt gactagaaag gctattaatg caatagcttc gcctcctgca
     8761 taaaataatc ccttcatttt tccattatac aaatccaatg ctaaagcttg ctgattttgc
     8821 tgacggtatt tactaaagaa agatctttct aataaaaaag atcgaatgac aataaaccct
     8881 tgaaagattt cagataaact actggtcatt tcactgttta actttagaat ttccctgctg
     8941 ctgttgcgta ataaaaagcc aaaaacacca cctgcaatga cagcaatagg tataataaat
     9001 aagcccacaa atgaaagcaa tagactaata tgggctagat aaagaaagat cgcaataaat
     9061 aataacggca attttataag gttaataaga tttcgcccaa tcattccatc tatactatta
     9121 atatcattag taaaatgaga aataaattct ccagagtggg ttgtatgaat tttatgaacg
     9181 ggagaaagta acagttgcct tagaagctgc tcttttaaat ctcgtttaat agaagatgtt
     9241 gcaaccgctt caatatatgt atcgtaatag attgtaagaa agcttataag tattagacca
     9301 aaagcaaatg gcagcaagtg cttaacgcgg gtaaagtctc cttgaacggc agcatctgaa
     9361 agatctccaa gaaaccatgc ggaggcaaga gtaattaaaa tgtccgtcaa taaaaaaagc
     9421 attagccctg cgtaagcttt ccaatgtttt ctaagcaaag ggtatacaat tgaaaaagcg
     9481 cttatcattt cctctttgtc aaaataccgc tttatatcag ctcgatttaa tttcatcata
     9541 acactccaaa aataagtgat tagcttaatt aactattttt tgattaatat atttttttaa
     9601 gaaacgggag ctaaaaggaa aaaaaagcat taaccagcac catatatagt caaaaggagc
     9661 agccatataa actttttttt gtttttttcg ggagattgcc gtcaatttcc caataacttg
     9721 ttctctcgtt acaggctcat cgcagtaaag gttagtatct cctttaaata tataatgcag
     9781 ctgctcgttc ttgtatcttg ttttaattaa tcgatgagca atcaattgcc cgcttttcgt
     9841 atgaaagaga ccaatatcac ctttttttaa aacaggtgct ttttcaaagg tgcaaaggtc
     9901 attttgacga atgcaagggt acatgctgaa cccctcagaa ggaaaatgga catacccttt
     9961 tttttctata acattcttca acaatactac gctttcttgg ttaattggca taatcaatca
    10021 atccatattt tatcaactca gagagaaagc tttccatatc ttcaaacgaa agctcgtcct
    10081 ctattcgata atccgtttgc aaagatctaa taagtgaagg aatagtacaa gggttttcga
    10141 gtaaagacca gcagcaacct cccaattcgt taatttttgt taccgtatat gcttccgtgt
    10201 ttaaaattac ccattcactg tcaagttgaa cggcctccat atcttgattt cgaataaact
    10261 gtttcattag gatatcaact cccaaaacgt attatttttt tgaaaataaa gatcatatac
    10321 aggtacataa tctaatacct cttttatcat ttgaacaatt ttctttgttt cttcgcggtc
    10381 tttattccaa taaaagactt tatccattat ttgaagtaaa gcacttgctt tacccagctt
    10441 tgttctctcg ttgttcaaag attgatgcag cagctgtata cttgctaatg gaatagttcc
    10501 tttaatagat ggagctgaga gctcactccg aaacggagaa ttaaacacag taatttgatt
    10561 tttttcaacc ttcagaagtg tggcttcatc agaaaggatg ggtcttggag cagacaattt
    10621 tgcgcaagtt gattttcctg cgccagattg gccagcaaat aaatgagcct ttcctttttc
    10681 agttgcacat gaggaatgaa taagtagtcc ccagttgtga taaacaatat aagaactata
    10741 aaagttcata agcgcatgtt ttaaagctaa ttcatcataa atttgaatgt gagcttctcc
    10801 cttgctcaaa tttgcttgaa ttctataatc agctctttga aaagatatag tatctgcttt
    10861 ttgttcaacg tctacttgat agtcaacaaa aggaactccg tatccatctt ctattcttat
    10921 aaccatatct ggacgttcaa tttcagcaaa aaaaggctcg tagttttttt gaattaaact
    10981 taaaatctga aatgaatgac aaacaattaa agcttgatgc tctccaattc ttattgtaac
    11041 tttttccatg ataggctcct tcaatctttt taatggagaa aaataattaa atgttaggca
    11101 tctctacaat tatctatatg tagcctttaa cactgatttg aaaataatag atcttgttaa
    11161 gatgcctaac aaataggttt aaagtctctt tttatattcg tttttacggt ctatttggat
    11221 tgtttggtgg aaaattaaca cctccattac catgtccagg gtggtcttgg ttaccttgtc
    11281 caggattcca gctttgagca gtttcaaatc taataggctg atgatccata accattgggc
    11341 gcttaggtga tacgcctggt tgtttttttg tcattttcat aatgtagtcc tcctttcaat
    11401 tcgtcgtatt attcagatta tatataataa tttgagggtt cttttttaac tccttgacct
    11461 cgataattaa agaagttact atacctcaac tctcagaagc aaagtgataa ggtttccccc
    11521 tcaactatta acctagtaac tagaaaaaca cttcacaaaa agtaatttgt ttcacatgaa
    11581 tttcacgctt ctacacattc ttttttaaat ttttatatgt cctttagaca aggggataaa
    11641 agatagttgt gacactactc gctttccttt catacttcgt aataatgttc attataaaga
    11701 acgaaatttc aacagatatc cctgactagt catttaaacc tattaaaccc gggctcacaa
    11761 tacttaataa ctagtttttt ctattataaa gaacaaaaca caaatagtaa acctttatta
    11821 agaacaaaaa agatataaat tttcacaaaa tttgtacctt tattaagaac atcacttatt
    11881 tttattttat ttacctttgt ttattattgg aatagaagca aatttatgtg gtagatgagt
    11941 aaaagtagta aaccgtcgta tatgtatcta gcaactataa atatataaat tttcaaccta
    12001 gttggttacg cttattatgt ataacaaaac accccttcta gtagacataa gtacacttaa
    12061 aacaattaag gactaaaagg ttctaagctg gttagttgaa agaagatata taataattta
    12121 tacactattg ttaaatagtg gtttactagt tcccttaatg aggtatatat tgggtactat
    12181 gaagtcgtga agaggtgtgg aatacttgtc attattttta aagtggaagc aaaagaagca
    12241 ggaaaaagaa gcagagcgtg ttcttgagga atcaatctca aaaagaaaag actactggaa
    12301 cacaattgga catgtagacg gagacgtatt aactcatttg ttaaatccca tgttttttgg
    12361 cggacctgct tggccatctg gacgtcaaac atttattcgt gttcaaaaaa cagagacggt
    12421 tattctcgca agcgacggct tgtccgatcc gtttcaatcc cccgaagaaa agagccgaaa
    12481 gcaaggaaaa ggattagaat tctatatcga atgcgatgat gaatctctgc gcggaccttt
    12541 atctgatatc caggatcact gggcatttga ccttctttat caaatgagtc aaaatgctgc
    12601 cgctcatcct aatatgctag aactattcat gaagcacgat attctttcaa ttgaatttac
    12661 tgatttggac gtaccgtctc attttgtaaa tgaaaatgga gaaattggtg tattgctagg
    12721 cgttcagtct ccttctgttt cagctagcct ctctttacct tacgaatcta ttaaactgat
    12781 tagcatgaag cttcttacac caaacgaatt agagtatgta cgcgaacaag gagcgcaagg
    12841 acgcaggcag ctcgctgaaa catttcagct gtcaaaaagt tatcatatta ccctgaccaa
    12901 aagagagtct cttatttaaa agaggttctt tttttatttt tgccgctgaa gacgaagccc
    12961 tatagaatat aagcgtcatt tatatgaagc tctagttcca atactttttt aaggctgctt
    13021 ttgatatgag cgtactattt ttgattcatg gtatattttg ctatagtaaa aaagaagata
    13081 taaaaaagga gatggacgtt agacatggca gaaaaagtac agattggaaa atccgaatta
    13141 tatgttaatc ctattggact tggaacaaac gctgtaggag gacataactt atatcctaac
    13201 ctaaacgaag aagtcggcaa agaccttgtt cataaggcgc tagataatgg cataaacctc
    13261 cttgatacag cgttcattta tggtccaaaa cgctctgaag aactaattgg tgaagtgcta
    13321 aaagaacgtg gaaatcgtga agaagcggtt atcgccacaa aaggagcaca taaaattgtt
    13381 ggagatgagg tactgctaga caactctcct gcgtttttaa aacagtcggt tgaagatagc
    13441 ttaaaacgcc ttcaaacaga ttatatcgat ttatattata ttcatttccc tgataaaaac
    13501 acaccaaaag acgaagcggt cggtgcgtta aaagaattaa aagatgaagg aaaaatccgt
    13561 tctattggcg tatcaaactt ctcgttagat cagttaaaag aagcaaataa agatggttat
    13621 gtagacgtgg tgcaagggca atataactta attcaaagag aagcagaaaa cgatatttta
    13681 ccttatacgg ctgcaaaccg catttcattt attccgtact tcccgctagc tgctggttta
    13741 cttgctggga aatacgataa aaacacaaag tttaatgact tgcgcgaaga tatgcctcat
    13801 tttatcgggg aagcatttca gcaaaatcta gaaaaagtag agcgtcttcg tcaaatctct
    13861 agcgcaaaag gcgtagaagt agctcatctt gttctggctt ggtacttaac gcgcgattca
    13921 attgatgtat taattccggg ggcaaaacgc gctgatcaag tacttgataa cttaaaaaca
    13981 ttagatgttc agctcacttc ttcggaaatt aaagacattg atcatatttt taaataatat
    14041 aaaaagagct ttgccatagg taaagctctt ttttctatac aattccgctg gttaatagaa
    14101 caaaagccgt aaggaagaat cccatctgta caaagcttgt tatgtactct ttggtttctt
    14161 gtttatattt ccattcatct atacctttca gcaaaatagc cgcaactaaa aataggcaag
    14221 acacgatata aggctcgaca aacataaaga tcatatcgag tactagaaaa agaacaaaag
    14281 ctatcgtcac atatttatcc catcgtccta aagctagact ttcatactca tatttacccc
    14341 aaaatttgct gcgaggtata tcaagcactt ttcttaaaat aaaatctact aagactgctg
    14401 ctgctactag catgatcaat atatacatcg tcatctctcc ttccttttta tggtatcatt
    14461 tcaactcgtt tctgttaagg tctcagccac aaagtgctta aactgctttg tttcttctgt
    14521 ttcgcctttt gttacgatat acgtatgtga agaaggccgg ataatttttt gctgtgaaat
    14581 tacgcttaac gtttgatttt caacttcctt tttcaccata gaaaatggca aataagatac
    14641 gcctaggcct tcttcaataa agcgctttgt aatttctact tgcgtcacag gaagcagctg
    14701 aatgtgagga taacaagcct tgatttgaag gagtaaatct tcccaataaa caggatgatt
    14761 attcgtaagg aggcggtagg aagataacag ctcctgttcc gtacgtgctc ctgcagaaaa
    14821 cggggcaact aagactgctt tttctttatg aattaactca taagaaacgt ctgcctgacc
    14881 cggaagcatc cttgttaatc caatatctga ccttctgtcg ctgatgtctt ttcccacttg
    14941 aaacgaattt gtgatattaa ccgttacttc aatatgggga tatctctcta caaattgttt
    15001 gattagactc ggcaaaacag atgctgctat ttgaggagca gcggatatag tcagttttcg
    15061 gttatatcct tgcttccata acctaaaatt ccctactcct tcttcatatg ctctcaccat
    15121 tttttgagca tgaggcaaaa aaaagcgtcc tgcctcagtc agcacgatat atttaccttt
    15181 tttttcaaaa agctcatctc ctaattcttg ctgcagtcgc tgaatatgct ttgatacagc
    15241 aggctgtgtt aaaaataaat cttcagacgc ttgcctgaaa ttttcataag aagccgctat
    15301 gatgaatgtt tttaaccatt tgatctccat tctcttctct ccatctcttt ctattcataa
    15361 caaactggaa tcaatactgc ttatttttgt ttattttctt ttctattaaa cttctatacg
    15421 atatatgtat ctcaatatta ccaaataaag gagctgtaaa aatgaaaaat aacgttaaag
    15481 aaaaatttaa tgctcatgct tctcagtatg atgagcagcg ccgcaaactc attccttgtt
    15541 tttttgattt ttattctatt cccgtttcgc ttcttcactt tccaaaaaag acgcttcgca
    15601 tacttgatat gggagcaggt acaggcttgt tttcttcttt tgttaaagaa aaatacccag
    15661 atgcgcattt cacgttgatt gacgtctcag atcaaatgct tgaaaaagca aaggaacgct
    15721 ttaaaaatga acagcatata gaatttatcg tatcagatat aacaagctac aaatttgagc
    15781 actcatttga cattgtgatt tcctcacttg ctattcatca tttagaagac gaacaaaaac
    15841 aaaagctgta tgaacaaatt tatgatttgc tgcatacagg aggaatattt attaatgccg
    15901 atcaagtatt aggcccttct tctattattg aagagttata taaaaaagac tggagcgaaa
    15961 gaattgccgc aagcggatta actcatgagc aaattgaggc tgctcatgaa cgtacgaagt
    16021 tagataaaat ggcaactttg cacgatcagt taaattggtt aacagcaagc gggttcagca
    16081 cggtggattg catctataaa ttttttaatt ttgttgtaat gtatgctcaa aaataacggt
    16141 ttaaaaacta cttgtctctt tgcaagtagt ttttttactc tttccctccc tatattcgaa
    16201 taagaatatt tatctatttc cacaaaacta cgcatacttc ttttccagtt tcgtatatct
    16261 aataatagct tcgttctcct gaacttttga tttttttgta cataaaaccc atataaagta
    16321 tttttatact attttatgtc tttttatggt acaaaaaata caaatatgtt acaatatgat
    16381 tacaaaaaaa tctatataac gctttcattt ctttacacaa aaatgaagaa ctggaaagga
    16441 tgtgatactt atgtaaatgt gaatccgcta gattagtaaa cttatattcc taaagttgta
    16501 caaagaatta agaaaaactt agttattctt attattataa attcccgcta gtaaagtctt
    16561 tctacttaat gatttcctta ttaagcgcat acatacaggg atagaaaatg cagctattcg
    16621 tcttttattt tattagtgaa gaatttatag cacagcccaa agcatcatac gtttttcatt
    16681 aatgcagcct aaggaggcgc agcacatggc aaatagaata tcaagaacag caatcgtact
    16741 catagcagct attttagctc tagcctgctt gtttgtagga gttccaaaaa cagaagctgc
    16801 ttcaacacca tctcatttaa ttatcattaa caaagcgacg aataaactcg cttattacca
    16861 aaatggttca cttgtccgaa cgttttcagt aggaacagga cgcacgcagt ctcttacacc
    16921 agaaggccat ttcaaagtag taaataaaat cgtcaatcgc ccttattaca aagggaacat
    16981 tcctggtgga gatcctagaa atccccttgg caatcgctgg ctaggcctaa atgcgagagg
    17041 tacatacggc acgacgtatg ctattcacgg aaataataat cctgcttcca tcggcaaata
    17101 tgtaagcagc ggatgcgttc gtatgtacga tgaagaagta gaatggttat ttagtaaagt
    17161 gaccgtcggt acaccggttg tgattacaac ttcttctaaa tcatttaacg acattgcagc
    17221 agcaaacgga tacaacgttt ctggaaactc aggttctact ccagctcctt ctacaggaac
    17281 tgttttaaag aaaggcagca aaggaaatgc agttaaagag cttcagcaga aactaacttc
    17341 acttggctat aatgcacaag gtacggacgg tgtgttcggt gccaatacag attcagctgt
    17401 tcgtaagttc caaaaagacc acggcttaac ggctgacggc attgttggcc catcaacata
    17461 taaagcttta ggaagttcag gaacgaaccc gacgacacca acaaacccaa caaatccaaa
    17521 gccaacaaat ccaccagcag atacaacaat taacacaaaa caaacgctta aaaaaggaag
    17581 caaaggcagc aatgttcaag ctcttcaaaa gaaattaaca gcgattggct ataatacaaa
    17641 aggtacggac ggtatcttcg gtgccaatac agaagctgct gtacgtaatt ttcaaaaaga
    17701 caataagcta gcagctgacg gcattgccgg acctaatact ttaactgcta tttccaaacg
    17761 ctaatagagc ctgatttcag gctctgtttt tttattgata aacctctttt ttacatcgcg
    17821 ccttgacccc ttaatgaacc agtacgccgt ctttcttttc tacgacatac ttaatcagat
    17881 gataaaccgt tctcataaga atttgctgct gatagatatc atttttggca ggaattacgt
    17941 tttctatcag tctgctatat ttgtaggctt gatcgtcttc tttttgttta taaagagcga
    18001 gccagtcatt acgggatttt tcaagcaact gttcgttgaa ataggaataa acgacggttg
    18061 caaactcacc tgccaattct tgaataacct gctgtcggtc ggtgaccgaa tgataggtac
    18121 ttgaccaccc agacggctgg cttagaaaat gctcgtagac agatgaaata aaagcggacg
    18181 taatgactgg caccggccct tcatgctctc ctaaggaaat gttcaaacac gtttctctgt
    18241 ccatataagg aatgttcagc gactccatcg cttcataaaa agcctgagag acagtcaagt
    18301 ttaaataaat aggatgcagc tcttgctgct tttttctcgt ttctgatact aaagctgcct
    18361 ttaagtcttt atacagaagg tgactctctt tgaattcctc gtgtacacat tctaaaatag
    18421 tcgtattccc tactgttaaa tagtagtgaa gctgcttttt cataagaggt gaaacgcttt
    18481 taagcgcacc atctatcatt ttagccatgg catgcttttt agcataatcc gtacggcagc
    18541 ttggagaggt aagcaaatct ccgtgtgtaa cacaaacgtt tactttagcg ccatgaccat
    18601 gtacgatgag ctgttgaaga aattgaatat ctaattcttt aagcccatga tgtacgtata
    18661 aaatagaagc tgctttttta aaagaatcgt ggatggtgct cgtatattca aaatacggat
    18721 gctcgcaaat cgctaaccct tttttaaaag aaaaagggcc gcaaacttca attctacgaa
    18781 acaatggata aataagacgt ccgttatttt cttcttcttc atttgttagc ggaccaaggg
    18841 aagacagctc ttttgctgtg agacggcagg atattggcca gtcgtcttct cctatttccc
    18901 atgttccttc cttgtattct ttcaaccggg attcaatggc cagaagcatt tgctcggtga
    18961 ttttcctaca ttcaagccgc ttgtgccatc cctctgcaaa atctcttcct tcttgatcaa
    19021 cagcgtcttt tactatttca ctttctcgtt taattgcatc tacaaattgt ttgaatgaac
    19081 tattttcgtc gttcattctt aaaggaacat cgtcattaaa ataacgggct ttgtatggga
    19141 tatctcccaa aagagcgcgc agattgaaag aggaatctcc gtgtaacaac tcaaagacca
    19201 agtcataatc cgtgcctcct tcagcataca cttcagcgct tcttagtagg atattctcca
    19261 atttcctttg cacttcactt cgcgtaaaaa aagagacagc agcttcatag tgttgggaat
    19321 ccttcacctt atacgtagca gaataagcgc ctttactgcc tattcctaga aagccacatt
    19381 ccttttttat accaagaagc tggcggatta aggatgtttt gccgcttcct tgttctccga
    19441 ttacatgaac gtactcatac tcgctgtcaa tttgttcgct cgtccttttt tcaatatcgt
    19501 tataaaaagc attcactact cgttcatcat atcttgcttt tgctcttcct tttgcagtac
    19561 ttgtccaaaa atcctgcact ctcagcagtt cattcatctc ttcaaccaga atgtcaattt
    19621 catcgtgttg ctctgtatac ataaaccgtt taacaaacgg gttcgatctt cctctttcat
    19681 cttttttaaa cggatgctga aacataattg accagccttt tcgcatagga gattgacagg
    19741 cttttgcacg aaaaactttc attcatttcc ccttctttcc ctaacattgt cctatttgaa
    19801 atgtatggct tttaaagggg ggatatgtct atgattttcc tctttttaga aggatttttc
    19861 cttcatttat cgaagtaatt aattgaggtg atgggagaat gttgacaaaa attgtgaaat
    19921 gcagcatacc gactgataaa aaagcatctt tttcatatac gcaacagcat tgggctgctc
    19981 ttgcacacgt gaatggtttc attggccaat tagggggttg gaacgtggaa gatgaaacag
    20041 atgcttgtat tctagctctg tgggaagatg gaacaactta tcaagaattc atgaagcata
    20101 ctcatgattc tattttttat aaaagcaagc aggatcaaac atatacgaat ttggacgttt
    20161 caacatcaga tccgtcctac ttcataggag cacgctacaa ttattatcga agcagcgcca
    20221 ttgaaagccg ttatttagta aagacggaaa ttgaagtcga tttttac
//
