Select genomic region:
Overview
3.1
12.1
12.2
12.3
13.1
22.1
22.2
24.1
25.1

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_NKAQ01000011 (original name was: NZ_NKAQ01000011.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 3.1 | terpene | 205,233 | 227,101 |

NZ_NKAQ01000002 (original name was: NZ_NKAQ01000002.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 12.1 | RRE-containing | 386,063 | 406,329 |
Region 12.2 | phosphonate | 631,905 | 673,422 |
Region 12.3 | terpene | 782,204 | 803,052 | carotenoid | Terpene | 50%

NZ_NKAQ01000020 (original name was: NZ_NKAQ01000020.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 13.1 | NRPS-like | 1 | 23,293 | 2,4-diacetylphloroglucinol | Polyketide | 25%

NZ_NKAQ01000003 (original name was: NZ_NKAQ01000003.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 22.1 | siderophore | 820,984 | 837,559 |
Region 22.2 | terpene | 1,003,322 | 1,024,140 | surfactin | NRP:Lipopeptide | 13%

NZ_NKAQ01000005 (original name was: NZ_NKAQ01000005.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 24.1 | lanthipeptide-class-i | 89,030 | 115,540 |

NZ_NKAQ01000006 (original name was: NZ_NKAQ01000006.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 25.1 | T3PKS | 367,777 | 408,862 |

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 3.1 | terpene | 205,233 | 227,101 |
Region 12.1 | RRE-containing | 386,063 | 406,329 |
Region 12.2 | phosphonate | 631,905 | 673,422 |
Region 12.3 | terpene | 782,204 | 803,052 | carotenoid | Terpene | 50%
Region 13.1 | NRPS-like | 1 | 23,293 | 2,4-diacetylphloroglucinol | Polyketide | 25%
Region 22.1 | siderophore | 820,984 | 837,559 |
Region 22.2 | terpene | 1,003,322 | 1,024,140 | surfactin | NRP:Lipopeptide | 13%
Region 24.1 | lanthipeptide-class-i | 89,030 | 115,540 |
Region 25.1 | T3PKS | 367,777 | 408,862 |

No secondary metabolite regions were found in these records:
  NZ_NKAQ01000001 (original name was: NZ_NKAQ01000001.1)
  NZ_NKAQ01000010 (original name was: NZ_NKAQ01000010.1)
  NZ_NKAQ01000012 (original name was: NZ_NKAQ01000012.1)
  NZ_NKAQ01000013 (original name was: NZ_NKAQ01000013.1)
  NZ_NKAQ01000014 (original name was: NZ_NKAQ01000014.1)
  NZ_NKAQ01000015 (original name was: NZ_NKAQ01000015.1)
  NZ_NKAQ01000016 (original name was: NZ_NKAQ01000016.1)
  NZ_NKAQ01000017 (original name was: NZ_NKAQ01000017.1)
  NZ_NKAQ01000018 (original name was: NZ_NKAQ01000018.1)
  NZ_NKAQ01000019 (original name was: NZ_NKAQ01000019.1)
  NZ_NKAQ01000021 (original name was: NZ_NKAQ01000021.1)
  NZ_NKAQ01000022 (original name was: NZ_NKAQ01000022.1)
  NZ_NKAQ01000023 (original name was: NZ_NKAQ01000023.1)
  NZ_NKAQ01000024 (original name was: NZ_NKAQ01000024.1)
  NZ_NKAQ01000025 (original name was: NZ_NKAQ01000025.1)
  NZ_NKAQ01000026 (original name was: NZ_NKAQ01000026.1)
  NZ_NKAQ01000027 (original name was: NZ_NKAQ01000027.1)
  NZ_NKAQ01000028 (original name was: NZ_NKAQ01000028.1)
  NZ_NKAQ01000004 (original name was: NZ_NKAQ01000004.1)
  NZ_NKAQ01000007 (original name was: NZ_NKAQ01000007.1)
  NZ_NKAQ01000008 (original name was: NZ_NKAQ01000008.1)
  NZ_NKAQ01000009 (original name was: NZ_NKAQ01000009.1)

Compact view
c00003_NZ_NKAQ.. - Region 1 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 205,233 - 227,101 nt. (total: 21,869 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000557.1 |  | 0.17 | RiPP | streptococcin A-FF22 | Streptococcus pyogenes
BGC0000526.1 |  | 0.17 | RiPP | macedocin | Streptococcus macedonicus
BGC0000547.1 |  | 0.17 | RiPP | salivaricin 9 | Streptococcus salivarius
BGC0001788.1 |  | 0.17 | RiPP | suicin 65 | Streptococcus suis
BGC0000545.1 |  | 0.16 | RiPP | ruminococcin A | [Ruminococcus] gnavus E1
BGC0000616.1 |  | 0.16 | RiPP | amylocyclicin | Bacillus velezensis FZB42
BGC0000563.1 |  | 0.16 | RiPP | venezuelin | Streptomyces venezuelae ATCC 10712
BGC0000554.1 |  | 0.16 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0000886.1 |  | 0.16 | Other | allylmalonyl-CoA | Streptomyces tsukubensis
BGC0001407.1 |  | 0.16 | RiPP | bicereucin | Bacillus cereus SJ1

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000557.1 |  | 0.48 | RiPP | streptococcin A-FF22 | Streptococcus pyogenes
BGC0000526.1 |  | 0.48 | RiPP | macedocin | Streptococcus macedonicus
BGC0000547.1 |  | 0.48 | RiPP | salivaricin 9 | Streptococcus salivarius
BGC0001788.1 |  | 0.47 | RiPP | suicin 65 | Streptococcus suis
BGC0000545.1 |  | 0.47 | RiPP | ruminococcin A | [Ruminococcus] gnavus E1
BGC0000616.1 |  | 0.47 | RiPP | amylocyclicin | Bacillus velezensis FZB42
BGC0000563.1 |  | 0.47 | RiPP | venezuelin | Streptomyces venezuelae ATCC 10712
BGC0000554.1 |  | 0.47 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0000886.1 |  | 0.46 | Other | allylmalonyl-CoA | Streptomyces tsukubensis
BGC0001407.1 |  | 0.46 | RiPP | bicereucin | Bacillus cereus SJ1

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00012_NZ_NKAQ.. - Region 1 - RRE-containing
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 386,063 - 406,329 nt. (total: 20,267 nt) Show pHMM detection rules used
RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RRE-containing | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001551.1 |  | 0.23 | RiPP | citrulassin E | Streptomyces glaucescens
BGC0000761.1 |  | 0.19 | Saccharide | exopolysaccharide | Methylobacillus sp. 12S
BGC0000916.1 |  | 0.19 | Other | molybdenum cofactor | Staphylococcus carnosus
BGC0000786.1 |  | 0.17 | Saccharide | O-antigen | Edwardsiella ictaluri 93-146
BGC0000782.1 |  | 0.17 | Saccharide | O-antigen | Burkholderia pseudomallei 1026b
BGC0000777.1 |  | 0.17 | Saccharide | lipopolysaccharide | Escherichia coli
BGC0000760.1 |  | 0.17 | Saccharide | emulsan | Acinetobacter venetianus RAG-1 = CIP 110063
BGC0000790.1 |  | 0.16 | Saccharide | O-antigen | Escherichia coli
BGC0000787.1 |  | 0.16 | Saccharide | O-antigen | Escherichia coli
BGC0001407.1 |  | 0.16 | RiPP | bicereucin | Bacillus cereus SJ1

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001551.1 |  | 0.56 | RiPP | citrulassin E | Streptomyces glaucescens
BGC0000761.1 |  | 0.51 | Saccharide | exopolysaccharide | Methylobacillus sp. 12S
BGC0000916.1 |  | 0.51 | Other | molybdenum cofactor | Staphylococcus carnosus
BGC0000786.1 |  | 0.48 | Saccharide | O-antigen | Edwardsiella ictaluri 93-146
BGC0000782.1 |  | 0.48 | Saccharide | O-antigen | Burkholderia pseudomallei 1026b
BGC0000777.1 |  | 0.48 | Saccharide | lipopolysaccharide | Escherichia coli
BGC0000760.1 |  | 0.48 | Saccharide | emulsan | Acinetobacter venetianus RAG-1 = CIP 110063
BGC0000790.1 |  | 0.47 | Saccharide | O-antigen | Escherichia coli
BGC0000787.1 |  | 0.47 | Saccharide | O-antigen | Escherichia coli
BGC0001407.1 |  | 0.46 | RiPP | bicereucin | Bacillus cereus SJ1

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00012_NZ_NKAQ.. - Region 2 - phosphonate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 631,905 - 673,422 nt. (total: 41,518 nt) Show pHMM detection rules used
phosphonate: phosphonates

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | phosphonate | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001859.1 |  | 0.28 | Other (Phosphonate) | fosfomycin | Pseudomonas syringae
BGC0000904.1 |  | 0.23 | Other | FR-900098 | Streptomyces rubellomurinus
BGC0000937.1 |  | 0.23 | Other | fosfazinomycin A | Streptomyces sp. WM6372
BGC0000926.1 |  | 0.19 | Other | rhizocticin A | Bacillus subtilis subsp. spizizenii ATCC 6633
BGC0001104.1 |  | 0.19 | NRP, Polyketide | myxovirescin A1 | Myxococcus xanthus DK 1622
BGC0000897.1 |  | 0.19 | Other | dehydrophos | Streptomyces luridus
BGC0002007.1 |  | 0.17 | Terpene | atolypene A, atolypene B | Amycolatopsis tolypomycina
BGC0001739.1 |  | 0.17 | Other | phosphonoacetic Acid | Streptomyces sp. NRRL F-525
BGC0002036.1 |  | 0.16 | Other | dehydrofosmidomycin | Streptomyces lavendulae
BGC0000885.1 |  | 0.16 | Other | 4-hydroxy-3-nitrosobenzamide | Streptomyces murayamaensis

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001859.1 |  | 0.61 | Other (Phosphonate) | fosfomycin | Pseudomonas syringae
BGC0000904.1 |  | 0.57 | Other | FR-900098 | Streptomyces rubellomurinus
BGC0000937.1 |  | 0.56 | Other | fosfazinomycin A | Streptomyces sp. WM6372
BGC0000926.1 |  | 0.51 | Other | rhizocticin A | Bacillus subtilis subsp. spizizenii ATCC 6633
BGC0001104.1 |  | 0.50 | NRP, Polyketide | myxovirescin A1 | Myxococcus xanthus DK 1622
BGC0000897.1 |  | 0.50 | Other | dehydrophos | Streptomyces luridus
BGC0002007.1 |  | 0.48 | Terpene | atolypene A, atolypene B | Amycolatopsis tolypomycina
BGC0001739.1 |  | 0.48 | Other | phosphonoacetic Acid | Streptomyces sp. NRRL F-525
BGC0002036.1 |  | 0.47 | Other | dehydrofosmidomycin | Streptomyces lavendulae
BGC0000885.1 |  | 0.47 | Other | 4-hydroxy-3-nitrosobenzamide | Streptomyces murayamaensis

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00012_NZ_NKAQ.. - Region 3 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 782,204 - 803,052 nt. (total: 20,849 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000647.1 |  | 0.33 | Terpene | carotenoid | Rhodobacter sphaeroides
BGC0000650.1 |  | 0.31 | Terpene | carotenoid | Algoriphagus sp. KK10202C
BGC0000645.1 |  | 0.27 | Terpene | carotenoid | Halobacillus halophilus DSM 2266
BGC0000885.1 |  | 0.24 | Other | 4-hydroxy-3-nitrosobenzamide | Streptomyces murayamaensis
BGC0000846.1 |  | 0.23 | Other | tabtoxin | Pseudomonas syringae
BGC0000858.1 |  | 0.23 | Other | ectoine | Methylobacter marinus
BGC0000937.1 |  | 0.23 | Other | fosfazinomycin A | Streptomyces sp. WM6372
BGC0000648.1 |  | 0.22 | Terpene | carotenoid | Myxococcus xanthus
BGC0001456.1 |  | 0.22 | Terpene | isorenieratene | Streptomyces argillaceus
BGC0000633.1 |  | 0.21 | Terpene | carotenoid | Streptomyces avermitilis

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000647.1 |  | 0.67 | Terpene | carotenoid | Rhodobacter sphaeroides
BGC0000650.1 |  | 0.65 | Terpene | carotenoid | Algoriphagus sp. KK10202C
BGC0000645.1 |  | 0.61 | Terpene | carotenoid | Halobacillus halophilus DSM 2266
BGC0000885.1 |  | 0.57 | Other | 4-hydroxy-3-nitrosobenzamide | Streptomyces murayamaensis
BGC0000846.1 |  | 0.56 | Other | tabtoxin | Pseudomonas syringae
BGC0000858.1 |  | 0.56 | Other | ectoine | Methylobacter marinus
BGC0000937.1 |  | 0.56 | Other | fosfazinomycin A | Streptomyces sp. WM6372
BGC0000648.1 |  | 0.55 | Terpene | carotenoid | Myxococcus xanthus
BGC0001456.1 |  | 0.55 | Terpene | isorenieratene | Streptomyces argillaceus
BGC0000633.1 |  | 0.54 | Terpene | carotenoid | Streptomyces avermitilis

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00013_NZ_NKAQ.. - Region 1 - NRPS-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1 - 23,293 nt. (total: 23,293 nt) Show pHMM detection rules used
Region on contig edge.
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
NRPS/PKS modules
Pfam domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | NRPS-like | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001527.1 |  | 0.31 | Other | basidioferrin | Gelatoporia subvermispora
BGC0001050.1 |  | 0.22 | NRP, Polyketide | thalassospiramide A | Tistrella bauzanensis
BGC0001627.1 |  | 0.22 | NRP | isonitrile lipopeptides | Mycobacterium tuberculosis H37Rv
BGC0002002.1 |  | 0.22 | NRP | 1,6-phenazinedimethanol, fontizine A | Serratia fonticola
BGC0001758.1 |  | 0.21 | NRP | rhizomide A, rhizomide B, rhizomide C | Paraburkholderia rhizoxinica HKI 454
BGC0001825.1 |  | 0.21 | NRP | xenematide | Xenorhabdus nematophila AN6/1
BGC0001641.1 |  | 0.20 | NRP | kolossin | Photorhabdus laumondii subsp. laumondii TTO1
BGC0000348.1 |  | 0.20 | NRP | ergovaline | Epichloe festucae var. lolii
BGC0001621.1 |  | 0.20 | NRP | imizoquin A, imizoquin B, imizoquin C, imizoquin D, TMC-2A, TMC-2B | Aspergillus flavus NRRL3357
BGC0000900.1 |  | 0.20 | Other | ferrichrome | Aspergillus oryzae

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001527.1 |  | 0.64 | Other | basidioferrin | Gelatoporia subvermispora
BGC0001050.1 |  | 0.55 | NRP, Polyketide | thalassospiramide A | Tistrella bauzanensis
BGC0001627.1 |  | 0.55 | NRP | isonitrile lipopeptides | Mycobacterium tuberculosis H37Rv
BGC0002002.1 |  | 0.55 | NRP | 1,6-phenazinedimethanol, fontizine A | Serratia fonticola
BGC0001758.1 |  | 0.54 | NRP | rhizomide A, rhizomide B, rhizomide C | Paraburkholderia rhizoxinica HKI 454
BGC0001825.1 |  | 0.53 | NRP | xenematide | Xenorhabdus nematophila AN6/1
BGC0001641.1 |  | 0.53 | NRP | kolossin | Photorhabdus laumondii subsp. laumondii TTO1
BGC0000348.1 |  | 0.53 | NRP | ergovaline | Epichloe festucae var. lolii
BGC0001621.1 |  | 0.53 | NRP | imizoquin A, imizoquin B, imizoquin C, imizoquin D, TMC-2A, TMC-2B | Aspergillus flavus NRRL3357
BGC0000900.1 |  | 0.53 | Other | ferrichrome | Aspergillus oryzae

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Module view
Shows module structures for each candidate in NRPS- and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here.
Legend
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 0 - 23293:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (thr) + (mal)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg13_16: thr
  Search NORINE for peptide: strict or relaxed
  AMP-binding (23..388): thr
  NRPSPredictor2: thr
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      ser, thr, dhpg, hpg
    Small clusters prediction:
      thr
    Single AA prediction:
      thr
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DFWNIGMiHK
    Nearest Stachelhaus code:
      thr
    Stachelhaus code match:
      90% (moderate)

c00022_NZ_NKAQ.. - Region 1 - siderophore
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 820,984 - 837,559 nt. (total: 16,576 nt) Show pHMM detection rules used
siderophore: IucA_IucC

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | siderophore | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000942.1 |  | 0.30 | Other | petrobactin | Bacillus anthracis str. Ames
BGC0001478.1 |  | 0.28 | Other | desferrioxamine E | Streptomyces sp. ID38640
BGC0000941.1 |  | 0.26 | Other | desferrioxamin B | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001572.1 |  | 0.26 | Other | desferrioxamine E | Pantoea agglomerans
BGC0000859.1 |  | 0.25 | Other | ectoine | Methylomicrobium alcaliphilum
BGC0000855.1 |  | 0.25 | Other | ectoine | Methylomicrobium kenyense
BGC0001531.1 |  | 0.25 | Other | bisucaberin B | Tenacibaculum mesophilum
BGC0000852.1 |  | 0.25 | Other | ectoine | Sporosarcina pasteurii
BGC0000856.1 |  | 0.24 | Other | ectoine | Methylophaga thalassica
BGC0001453.1 |  | 0.23 | Other | desferrioxamine | Streptomyces argillaceus

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000942.1 |  | 0.63 | Other | petrobactin | Bacillus anthracis str. Ames
BGC0001478.1 |  | 0.61 | Other | desferrioxamine E | Streptomyces sp. ID38640
BGC0000941.1 |  | 0.60 | Other | desferrioxamin B | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001572.1 |  | 0.59 | Other | desferrioxamine E | Pantoea agglomerans
BGC0000859.1 |  | 0.58 | Other | ectoine | Methylomicrobium alcaliphilum
BGC0000855.1 |  | 0.58 | Other | ectoine | Methylomicrobium kenyense
BGC0001531.1 |  | 0.58 | Other | bisucaberin B | Tenacibaculum mesophilum
BGC0000852.1 |  | 0.58 | Other | ectoine | Sporosarcina pasteurii
BGC0000856.1 |  | 0.57 | Other | ectoine | Methylophaga thalassica
BGC0001453.1 |  | 0.56 | Other | desferrioxamine | Streptomyces argillaceus

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00022_NZ_NKAQ.. - Region 2 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,003,322 - 1,024,140 nt. (total: 20,819 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000548.1 |  | 0.17 | RiPP | salivaricin A | Streptococcus salivarius
BGC0000554.1 |  | 0.16 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0000504.1 |  | 0.16 | RiPP | cytolysin ClyLl, cytolysin ClyLs | Plasmid pAD1
BGC0000516.1 |  | 0.16 | RiPP | geobacillin II | Geobacillus thermodenitrificans
BGC0000527.1 |  | 0.16 | RiPP | mersacidin | Bacillus sp. HIL-Y85/54728
BGC0000502.1 |  | 0.16 | RiPP | cerecidin, cerecidin A1, cerecidin A2, cerecidin A3, cerecidin A4, cerecidin A5, cerecidin A6, cerecidin A7 | Bacillus cereus
BGC0001210.1 |  | 0.15 | RiPP | pseudomycoicidin | Bacillus pseudomycoides DSM 12442
BGC0000496.1 |  | 0.15 | RiPP | AmfS | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000558.1 |  | 0.15 | RiPP | sublancin 168 | Bacillus subtilis subsp. subtilis str. 168
BGC0000539.1 |  | 0.15 | RiPP | nukacin ISK-1 | Staphylococcus warneri

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000548.1 |  | 0.48 | RiPP | salivaricin A | Streptococcus salivarius
BGC0000554.1 |  | 0.47 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0000504.1 |  | 0.47 | RiPP | cytolysin ClyLl, cytolysin ClyLs | Plasmid pAD1
BGC0000516.1 |  | 0.46 | RiPP | geobacillin II | Geobacillus thermodenitrificans
BGC0000527.1 |  | 0.46 | RiPP | mersacidin | Bacillus sp. HIL-Y85/54728
BGC0000502.1 |  | 0.46 | RiPP | cerecidin, cerecidin A1, cerecidin A2, cerecidin A3, cerecidin A4, cerecidin A5, cerecidin A6, cerecidin A7 | Bacillus cereus
BGC0001210.1 |  | 0.46 | RiPP | pseudomycoicidin | Bacillus pseudomycoides DSM 12442
BGC0000496.1 |  | 0.46 | RiPP | AmfS | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000558.1 |  | 0.46 | RiPP | sublancin 168 | Bacillus subtilis subsp. subtilis str. 168
BGC0000539.1 |  | 0.46 | RiPP | nukacin ISK-1 | Staphylococcus warneri

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
c00024_NZ_NKAQ.. - Region 1 - lanthipeptide-class-i
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 89,030 - 115,540 nt. (total: 26,511 nt) Show pHMM detection rules used
lanthipeptide-class-i: ((LANC_like and (Lant_dehydr_N or Lant_dehydr_C)) and not (YcaO or TIGR03882))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Lanthipeptides
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | lanthipeptide-class-i | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000543.1 |  | 0.29 | RiPP | pep5 | Staphylococcus epidermidis
BGC0000542.1 |  | 0.27 | RiPP | paenicidin B | Paenibacillus terrae
BGC0000541.1 |  | 0.27 | RiPP | paenicidin A | Paenibacillus polymyxa
BGC0000538.1 |  | 0.27 | RiPP | nisin Z | Lactococcus lactis
BGC0001289.1 |  | 0.27 | RiPP | penisin | Paenibacillus ehimensis
BGC0000503.1 |  | 0.26 | RiPP | cinnamycin | Streptomyces cinnamoneus
BGC0000528.1 |  | 0.26 | RiPP | michiganin A | Clavibacter michiganensis subsp. michiganensis NCPPB 382
BGC0000540.1 |  | 0.25 | RiPP | paenibacillin | Paenibacillus polymyxa OSY-DF
BGC0001579.1 |  | 0.25 | RiPP | duramycin | Streptomyces cinnamoneus
BGC0000563.1 |  | 0.25 | RiPP | venezuelin | Streptomyces venezuelae ATCC 10712

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000543.1 |  | 0.63 | RiPP | pep5 | Staphylococcus epidermidis
BGC0000542.1 |  | 0.60 | RiPP | paenicidin B | Paenibacillus terrae
BGC0000541.1 |  | 0.60 | RiPP | paenicidin A | Paenibacillus polymyxa
BGC0000538.1 |  | 0.60 | RiPP | nisin Z | Lactococcus lactis
BGC0001289.1 |  | 0.60 | RiPP | penisin | Paenibacillus ehimensis
BGC0000503.1 |  | 0.59 | RiPP | cinnamycin | Streptomyces cinnamoneus
BGC0000528.1 |  | 0.59 | RiPP | michiganin A | Clavibacter michiganensis subsp. michiganensis NCPPB 382
BGC0000540.1 |  | 0.59 | RiPP | paenibacillin | Paenibacillus polymyxa OSY-DF
BGC0001579.1 |  | 0.59 | RiPP | duramycin | Streptomyces cinnamoneus
BGC0000563.1 |  | 0.58 | RiPP | venezuelin | Streptomyces venezuelae ATCC 10712

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Lanthipeptide predictions
Lists the possible core peptides for each biosynthetic enzyme, including the predicted class. Each core peptide shows the leader and core peptide sequences, separated by a dash.

#### Lanthipeptide(s) for ctg24_96 - Putative Class I

ctg24_97 leader / core peptide
  MNNVKNLFDLDVQVTTASSDVDPQ - IDhb DhaVDhaLC DhbPGCGDDhbGDhaWNDhaFC C
allorf_105781_105921 leader / core peptide
  MNNVKNLFDLDVQVTTASSDVDPQ - IDhb DhaVDhaLC DhbPGCGDDhbGDhaWNDhaFC C

#### Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
Lanthipeptides
Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists the number of lanthionine bridges, possible molecular weights, and the scores for cleavage site prediction and RODEO.

ctg24_97 - Class I
  Cleavage pHMM score: 13.90
  RODEO score: 31
  Monoisotopic mass: 2064.9 Da
  Molecular weight: 2066.4 Da
  Number of bridges: 3
  Additional modifications: AviCys
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    2084.4 Da N = 1
    2102.4 Da N = 2
    2120.4 Da N = 3
allorf_105781_105921 - Class I
  Cleavage pHMM score: 13.90
  RODEO score: 28
  Monoisotopic mass: 2064.9 Da
  Molecular weight: 2066.4 Da
  Number of bridges: 3
  Additional modifications: AviCys
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    2084.4 Da N = 1
    2102.4 Da N = 2
    2120.4 Da N = 3

c00025_NZ_NKAQ.. - Region 1 - T3PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 367,777 - 408,862 nt. (total: 41,086 nt) Show pHMM detection rules used
T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | T3PKS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000282.1 |  | 0.34 | Polyketide | alkylresorcinol | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001962.1 |  | 0.31 | Polyketide | hierridin B, hierridin C | Cyanobium sp. LEGE 06113
BGC0001938.1 |  | 0.31 | Polyketide | entotheonella | Candidatus Entotheonella serta
BGC0001310.1 |  | 0.25 | Terpene | naringenin | Streptomyces clavuligerus ATCC 27064
BGC0001831.1 |  | 0.22 | Polyketide | alkylpyrone-407, alkylpyrone-393 | Myxococcus xanthus DK 1622
BGC0000528.1 |  | 0.17 | RiPP | michiganin A | Clavibacter michiganensis subsp. michiganensis NCPPB 382
BGC0001526.1 |  | 0.16 | Other | bartolosides E, bartolosides F, bartolosides G, bartolosides H, bartolosides I, bartolosides J, bartolosides K | Synechocystis salina LEGE 06099
BGC0000554.1 |  | 0.16 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0001525.1 |  | 0.16 | Other | bartoloside 2, bartoloside 3, bartoloside 4 | Synechocystis salina LEGE 06155
BGC0000551.1 |  | 0.16 | RiPP | SapB | Streptomyces coelicolor A3(2)

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000282.1 |  | 0.67 | Polyketide | alkylresorcinol | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001962.1 |  | 0.65 | Polyketide | hierridin B, hierridin C | Cyanobium sp. LEGE 06113
BGC0001938.1 |  | 0.64 | Polyketide | entotheonella | Candidatus Entotheonella serta
BGC0001310.1 |  | 0.59 | Terpene | naringenin | Streptomyces clavuligerus ATCC 27064
BGC0001831.1 |  | 0.55 | Polyketide | alkylpyrone-407, alkylpyrone-393 | Myxococcus xanthus DK 1622
BGC0000528.1 |  | 0.48 | RiPP | michiganin A | Clavibacter michiganensis subsp. michiganensis NCPPB 382
BGC0001526.1 |  | 0.47 | Other | bartolosides E, bartolosides F, bartolosides G, bartolosides H, bartolosides I, bartolosides J, bartolosides K | Synechocystis salina LEGE 06099
BGC0000554.1 |  | 0.47 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0001525.1 |  | 0.47 | Other | bartoloside 2, bartoloside 3, bartoloside 4 | Synechocystis salina LEGE 06155
BGC0000551.1 |  | 0.46 | RiPP | SapB | Streptomyces coelicolor A3(2)

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names