LOCUS       NZ_LR134338.1          21155 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_LR134338.1 Brevibacillus brevis strain NCTC2611 chromosome 1,
            complete sequence.
ACCESSION   NZ_LR134338
VERSION     NZ_LR134338.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 16:13:08
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 5508921
            Orig. end    :: 5530076
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21155
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5518921:5520076](-)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11155)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..21155
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21155
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="16"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(968..2485)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 126.9; E-value:
                     1.7e-38)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_5306"
                     /transl_table=11
                     /translation="MAQHAFLLEMNHIHKEFPGVKALDDVTLKVRPGTVHALMGENGAG
                     KSTLMKCLFGIYRPDAGEILLNNEQVTMSSSKDALAHGISMIHQELHPVPFRNVMENIW
                     LGRFPVKRIGPFPFVDETRMLADTKKLFADLGMDLNPHAVVRDLSVSKVQSLEIAKAVS
                     YQSKVIIMDEPTSSLTGNEVEQLFAIIRELKSRGVAIIYISHKMEEILRIADDVTIMRD
                     GKLIGTWRAAELTTDLIISKMVGRDLTQRFPSRSNSPGEPILKVEGLSSPFSQSFQHVS
                     FELRKGEILGVGGLVGAQRTELIEALFGLRAVSAGKVSINGQEVRIKSPKDAKKHKMAL
                     LTEERRVTGIIPVLSILENTVIANLASYQTPFLLLNERKRRADVSRSIEMLRVKTPSMK
                     ALIKNLSGGNQQKVLLARWLLTDPDILLLDEPTRGVDVGAKYEIYTIIAELASQGKGII
                     MISSEMPELLGMSDRIMVMCEGRLSGFLSGTAATEEEIMRLATKHLA"
     PFAM_domain     complement(1190..1654)
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_5306_0910"
                     /evalue="2.20E-19"
                     /label="ctg1_5306"
                     /locus_tag="ctg1_5306"
                     /protein_end="432"
                     /protein_start="277"
                     /score="70.4"
                     /tool="antismash"
                     /translation="QHVSFELRKGEILGVGGLVGAQRTELIEALFGLRAVSAGKVSING
                     QEVRIKSPKDAKKHKMALLTEERRVTGIIPVLSILENTVIANLASYQTPFLLLNERKRR
                     ADVSRSIEMLRVKTPSMKALIKNLSGGNQQKVLLARWLLTDPDILLLDEPT"
     PFAM_domain     complement(1958..2419)
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_5306_0909"
                     /evalue="2.00E-26"
                     /label="ctg1_5306"
                     /locus_tag="ctg1_5306"
                     /protein_end="176"
                     /protein_start="22"
                     /score="93.2"
                     /tool="antismash"
                     /translation="LDDVTLKVRPGTVHALMGENGAGKSTLMKCLFGIYRPDAGEILLN
                     NEQVTMSSSKDALAHGISMIHQELHPVPFRNVMENIWLGRFPVKRIGPFPFVDETRMLA
                     DTKKLFADLGMDLNPHAVVRDLSVSKVQSLEIAKAVSYQSKVIIMDEPTS"
     CDS             complement(2569..3615)
                     /gene_functions="transport (smcogs) SMCOG1205:ABC
                     transporter, carbohydrate uptake (Score: 158.9; E-value:
                     2.3e-48)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_5307"
                     /transl_table=11
                     /translation="MRKLIATTLVAAVTLSVVGCSQSGGSQPAASGGGSSPAGNPKIGV
                     AIYKFDDTFMTGVRNAISKAAEGKAEVDIVDSQNAQPTQNDKVDLFINKKVNALAINPV
                     DRTAAGVLIDKAKQANIPVVFFNREPMPEDMQKWDKVYYVGAKAEESGTISGELIVDYW
                     KANPEADKNKDGVLQYVMLKGEPGHQDAELRTKFSVKAIEDAGIKVEKVAEDTAMWDRV
                     KGQEKMAAFLAASGDKIEAVLANNDDMALGAIEALKASGYFANGKYMPVVGVDATAPAL
                     KELEAGTLLGTVLNDANNQGKATLSIAASLAKGETPTKDSTGFDITDGKYVWVPYKKIT
                     KENMNDAK"
     PFAM_domain     complement(2671..3489)
                     /aSDomain="Peripla_BP_4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13407.8"
                     /description="Periplasmic binding protein domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_5307_0911"
                     /evalue="6.90E-59"
                     /label="ctg1_5307"
                     /locus_tag="ctg1_5307"
                     /protein_end="315"
                     /protein_start="42"
                     /score="199.6"
                     /tool="antismash"
                     /translation="IGVAIYKFDDTFMTGVRNAISKAAEGKAEVDIVDSQNAQPTQNDK
                     VDLFINKKVNALAINPVDRTAAGVLIDKAKQANIPVVFFNREPMPEDMQKWDKVYYVGA
                     KAEESGTISGELIVDYWKANPEADKNKDGVLQYVMLKGEPGHQDAELRTKFSVKAIEDA
                     GIKVEKVAEDTAMWDRVKGQEKMAAFLAASGDKIEAVLANNDDMALGAIEALKASGYFA
                     NGKYMPVVGVDATAPALKELEAGTLLGTVLNDANNQGKATLSIAASLAKGE"
     CDS             complement(3742..4728)
                     /gene_functions="transport (smcogs) SMCOG1205:ABC
                     transporter, carbohydrate uptake (Score: 148.9; E-value:
                     2.5e-45)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_5308"
                     /transl_table=11
                     /translation="MRTAAVKRLSVYGLVVLAVVTLFCSCSAPLTDGEVGKKKTVALIV
                     RMKHGDYWRTVKLGAEMAAKEYERNLNFYAPDYEEDAHRQMELVQQAIADGSETIVVAP
                     SDEHVLREAIKLARERAIPILVLDTVGKDSAVKSYIGTDNYDMGMKAFEKMMYLIEKKG
                     QIALLGTDRVKANAKRREQGVLDLLPRETQVELIANENVPLDKKQIGEWTRELIRKHPQ
                     LKGVIALDASTAIGVAEEMENSGLRDKVKIVAIDSPPEVLEYLQEGIISATIIQKPLSM
                     GYLGVKYAVEASNGEAVPSLVDTGTKAIDRENMFWSENQKLLFPFVK"
     PFAM_domain     complement(3841..4593)
                     /aSDomain="Peripla_BP_4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13407.8"
                     /description="Periplasmic binding protein domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_5308_0912"
                     /evalue="3.50E-46"
                     /label="ctg1_5308"
                     /locus_tag="ctg1_5308"
                     /protein_end="296"
                     /protein_start="45"
                     /score="158.0"
                     /tool="antismash"
                     /translation="RMKHGDYWRTVKLGAEMAAKEYERNLNFYAPDYEEDAHRQMELVQ
                     QAIADGSETIVVAPSDEHVLREAIKLARERAIPILVLDTVGKDSAVKSYIGTDNYDMGM
                     KAFEKMMYLIEKKGQIALLGTDRVKANAKRREQGVLDLLPRETQVELIANENVPLDKKQ
                     IGEWTRELIRKHPQLKGVIALDASTAIGVAEEMENSGLRDKVKIVAIDSPPEVLEYLQE
                     GIISATIIQKPLSMGYLGVKYAVEASNGE"
     CDS             complement(4725..6488)
                     /locus_tag="ctg1_5309"
                     /transl_table=11
                     /translation="MKRLLVVIKVKGIQFIITTSFTLVTVLVMLFVGVMLYGKFAQTAE
                     QNAYLHTQQILEQVKYNLESYMNGMTQIFELVDDKIRRSKGLTADELNEQLETIVETRK
                     DIVSIAVFTRDGTLLATTPSKVLRKNTRLTEQSWFQKAIEDPTNLSFSLPHIQNLFKGE
                     YTWVVSMSREILLHGPDGEIPAVLLVDVNFKEIDELCQRVGLGKKGYVYIIDLVGNIVY
                     HPQQQLIYAGLKNENRSLPLKHSYGSYVEETQDEARLITIKTIDQLGWKIIGVSYMDEI
                     VTTKKEISRFIFWLLIFVIVIVLFVLYYLSAKISRPIKLLERSMEKVEQGDFSESEPIR
                     GSHEVEQLSLRFHLMVAKVRELMHQIIREQEAKRKSELEVLQAQINPHFLYNTLNSVVR
                     MVGNGKNEDVITTITSLSKLFRISLSRGKNIITVREELEHVRHYLIIQKMRYKQKFEYE
                     IVVENEDEVLNCLTLKLLLQPIVENAIYHGIEHLADPGWIRIFAALIDGKVLLQVSDNG
                     LGMSPDVLAQVKAGFYRSEEGSGVGIQNVQERIRLTFGEQYGLEIASEQEEGTVVRVWI
                     PRQVAEERDRL"
     PFAM_domain     complement(4755..5063)
                     /aSDomain="HATPase_c"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02518.28"
                     /description="Histidine kinase-, DNA gyrase B-, and
                     HSP90-like ATPase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_5309_0916"
                     /evalue="3.40E-10"
                     /label="ctg1_5309"
                     /locus_tag="ctg1_5309"
                     /protein_end="578"
                     /protein_start="475"
                     /score="40.5"
                     /tool="antismash"
                     /translation="LLQPIVENAIYHGIEHLADPGWIRIFAALIDGKVLLQVSDNGLGM
                     SPDVLAQVKAGFYRSEEGSGVGIQNVQERIRLTFGEQYGLEIASEQEEGTVVRVWIPR"
     PFAM_domain     complement(5124..5360)
                     /aSDomain="His_kinase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06580.15"
                     /description="Histidine kinase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_5309_0915"
                     /evalue="9.70E-26"
                     /label="ctg1_5309"
                     /locus_tag="ctg1_5309"
                     /protein_end="455"
                     /protein_start="376"
                     /score="90.0"
                     /tool="antismash"
                     /translation="ELEVLQAQINPHFLYNTLNSVVRMVGNGKNEDVITTITSLSKLFR
                     ISLSRGKNIITVREELEHVRHYLIIQKMRYKQKF"
     PFAM_domain     complement(5409..5561)
                     /aSDomain="HAMP"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00672.27"
                     /description="HAMP domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_5309_0914"
                     /evalue="2.00E-06"
                     /label="ctg1_5309"
                     /locus_tag="ctg1_5309"
                     /protein_end="360"
                     /protein_start="309"
                     /score="28.2"
                     /tool="antismash"
                     /translation="LSAKISRPIKLLERSMEKVEQGDFSESEPIRGSHEVEQLSLRFHL
                     MVAKVR"
     PFAM_domain     complement(5667..6362)
                     /aSDomain="dCache_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02743.20"
                     /description="Cache domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_5309_0913"
                     /evalue="2.40E-22"
                     /label="ctg1_5309"
                     /locus_tag="ctg1_5309"
                     /protein_end="274"
                     /protein_start="42"
                     /score="79.7"
                     /tool="antismash"
                     /translation="TAEQNAYLHTQQILEQVKYNLESYMNGMTQIFELVDDKIRRSKGL
                     TADELNEQLETIVETRKDIVSIAVFTRDGTLLATTPSKVLRKNTRLTEQSWFQKAIEDP
                     TNLSFSLPHIQNLFKGEYTWVVSMSREILLHGPDGEIPAVLLVDVNFKEIDELCQRVGL
                     GKKGYVYIIDLVGNIVYHPQQQLIYAGLKNENRSLPLKHSYGSYVEETQDEARLITIKT
                     IDQLGWKIIG"
     CDS             complement(6492..8096)
                     /gene_functions="regulatory (smcogs) SMCOG1016:LuxR family
                     DNA-binding response regulator (Score: 112.8; E-value:
                     2.3e-34)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_5310"
                     /transl_table=11
                     /translation="MYKLILVDDEEDVREGVSQEIDWHSYGYEVVAKAENGREALELVE
                     RLRPDVVVTDIKMPFMNGLQLAESIGRDYPAIRIIILTGFDEFEYAQKAVKLQIDEYVL
                     KPFSASELLEALDKVKRRMDEEAAHRENVQLLRDSYRKSLPVLREVFLSSLLSRQLVQH
                     DVYSKACEYGIELRSPEYLVAVICVDQPKQEEQQLFLFAVKNIAEEQLNAGKQAGIVFL
                     HEDQVVLLMRTKADDTQRIEVQTQNIAEEIRRTIEKYMSITVTIGIGNVVTDVAALPYS
                     YEDAMQALDYRSILGCNRMIVINDVEKQASEQIRLDERREHELVRCIKMGTSAELRNVI
                     DELFDQVARVPVSIEDYRIYLLEIMTTILKTAHRAEVDMDQLFGGQRYLLQVMTTFTGM
                     EDAREQITDICERLMASIANGRQTTYRRLITQALDYTHAHYHSPDISIHKVCDHLHISL
                     GYFSSIFKKETKTTFVTYLLSLRMEKAKELLRTTDLKSFEIAEKVGYTDPNYFSFSFRK
                     YAGMSAKEYRSQSEQEG"
     PFAM_domain     complement(6513..6746)
                     /aSDomain="HTH_18"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12833.9"
                     /description="Helix-turn-helix domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_5310_0919"
                     /evalue="1.40E-17"
                     /label="ctg1_5310"
                     /locus_tag="ctg1_5310"
                     /protein_end="528"
                     /protein_start="450"
                     /score="63.8"
                     /tool="antismash"
                     /translation="CDHLHISLGYFSSIFKKETKTTFVTYLLSLRMEKAKELLRTTDLK
                     SFEIAEKVGYTDPNYFSFSFRKYAGMSAKEYRS"
     PFAM_domain     complement(7224..7610)
                     /aSDomain="GGDEF_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF17853.3"
                     /description="GGDEF-like domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_5310_0918"
                     /evalue="5.00E-18"
                     /label="ctg1_5310"
                     /locus_tag="ctg1_5310"
                     /protein_end="291"
                     /protein_start="162"
                     /score="65.6"
                     /tool="antismash"
                     /translation="HDVYSKACEYGIELRSPEYLVAVICVDQPKQEEQQLFLFAVKNIA
                     EEQLNAGKQAGIVFLHEDQVVLLMRTKADDTQRIEVQTQNIAEEIRRTIEKYMSITVTI
                     GIGNVVTDVAALPYSYEDAMQALDY"
     PFAM_domain     complement(7749..8084)
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_5310_0917"
                     /evalue="3.40E-29"
                     /label="ctg1_5310"
                     /locus_tag="ctg1_5310"
                     /protein_end="116"
                     /protein_start="4"
                     /score="101.4"
                     /tool="antismash"
                     /translation="ILVDDEEDVREGVSQEIDWHSYGYEVVAKAENGREALELVERLRP
                     DVVVTDIKMPFMNGLQLAESIGRDYPAIRIIILTGFDEFEYAQKAVKLQIDEYVLKPFS
                     ASELLEAL"
     CDS             complement(8166..8651)
                     /locus_tag="ctg1_5311"
                     /transl_table=11
                     /translation="MNPMIQNIIQLRKEGHLDEAIQLALQLVSQSPTDPVAHYQCAWCH
                     DAAGLEKEAVPFYEKAIELGLSVEDDLQGALLGLGSTYRTLGQYEQAAATLAKGMQQFP
                     CDRSFPIFLSMAYYNLGKHHEAMTLLLKNLAETSSDPAILAYQKAILFYADDLNKTW"
     PFAM_domain     complement(8181..8549)
                     /aSDomain="TPR_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12688.9"
                     /description="Tetratrico peptide repeat"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_5311_0920"
                     /evalue="4.40E-12"
                     /label="ctg1_5311"
                     /locus_tag="ctg1_5311"
                     /protein_end="157"
                     /protein_start="34"
                     /score="46.4"
                     /tool="antismash"
                     /translation="PVAHYQCAWCHDAAGLEKEAVPFYEKAIELGLSVEDDLQGALLGL
                     GSTYRTLGQYEQAAATLAKGMQQFPCDRSFPIFLSMAYYNLGKHHEAMTLLLKNLAETS
                     SDPAILAYQKAILFYADDL"
     CDS             complement(8727..9965)
                     /locus_tag="ctg1_5312"
                     /transl_table=11
                     /translation="VNISGDSILKMHPLARRAENEEEILIGRTDISNFIVLPAIGVEII
                     DMLDEGKSINEVATIMEERLGEPVDVLDFAQDLIGSYQFVYMADGEVVNEPVPVVDHFS
                     WIKQGTGQFFFNRVAFGLYGILFFTGLLICVFTGKYIPVYSDIFVSSSVTVSVVVSFVA
                     TWVFLFFHEMAHLMAARSLGIGSRIGLGHRLVFAVAETNMSNIVLVDPQRRYRAFLAGM
                     SWDAMFMGIGVILLFANDQGWLTLVPFMEAFIRMLNVILLMALAFQFMVFMQTDLYYVL
                     ATKFQCSNLMVNTRLFLKAKFRSLTQDEQEEWEYVADHEKRVIRWYSWVYLIGSVWGIW
                     FFVQYQLRMAVDFIWIIADDMKNASLHSWEFWDGILLILLVLVPFLILGWSWMRAYRQR
                     RSERERTKSLQGT"
     CDS             complement(10001..11155)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Pantocin_Microcin_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ThiF"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_5313"
                     /sec_met_domain="ThiF (E-value: 1e-48, bitscore: 164.4,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="Pantocin_Microcin_RRE (E-value: 2.4e-14,
                     bitscore: 51.8, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERRPLFKPVHPVYEVTEQMIRLGEAPGYTFELEDENGSIRKMIK
                     LMDGTRTVGEIHTLLAVDYPEITYEEIVEAVESLSALGFLMDQAKEEASVLTSEQKERY
                     KANIRYFSLFTDLNQSPSELQEQVSRKKVTILGMGAFGSTLLVNLVGAGIQHIKLVDFD
                     RVELSNLNRQMVFNEKDIGRLKVEAARDFIGRLHSEVLIETETLQIKSSEDVERVIAGS
                     DLVMLAADQPFFFLQRWVNHACAKLQIPFIAGGFNLIEGQFFMVEPGKTGCIDCMHLHR
                     SRQIEDYPQLIQRLLDTNFILPTATIAPNTMMITGMMASDAIRYLTGIAPVQSAGKFII
                     FDFNTLEKSVFFEWERNEAECPTCGRGSGTEPIFHIKRKEVLAK"
     PFAM_domain     complement(10070..10795)
                     /aSDomain="ThiF"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00899.23"
                     /description="ThiF family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_5313_0921"
                     /evalue="8.20E-46"
                     /label="ctg1_5313"
                     /locus_tag="ctg1_5313"
                     /protein_end="362"
                     /protein_start="120"
                     /score="156.0"
                     /tool="antismash"
                     /translation="PSELQEQVSRKKVTILGMGAFGSTLLVNLVGAGIQHIKLVDFDRV
                     ELSNLNRQMVFNEKDIGRLKVEAARDFIGRLHSEVLIETETLQIKSSEDVERVIAGSDL
                     VMLAADQPFFFLQRWVNHACAKLQIPFIAGGFNLIEGQFFMVEPGKTGCIDCMHLHRSR
                     QIEDYPQLIQRLLDTNFILPTATIAPNTMMITGMMASDAIRYLTGIAPVQSAGKFIIFD
                     FNTLEKSVFFEWERNEAECP"
     CDS             11659..12216
                     /gene_functions="regulatory (smcogs) SMCOG1032:RNA
                     polymerase, sigma-24 subunit, ECF subfamily (Score: 127.7;
                     E-value: 5.9e-39)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_5314"
                     /transl_table=11
                     /translation="MEEDRVIIGRVLQGNKDSYSEIITRYHGKVSSILRKMLGHTPDAQ
                     DIVQEIFIKTYYHLPEYKTNYDFSAWLYRIAANHCLDELRKRKRKQQLTTSEEIEPVDS
                     HTPEVAFLNKEGQRLLRQRMMSVEEKYRIVLEMRYFESLSCEEISHRLSIPSSTVRTRL
                     SRGKDKLREAIGHAGQGGDFHL"
     aSDomain        11713..12177
                     /aSDomain="TIGR02937"
                     /aSTool="tigrfam"
                     /description="sigma70-ECF: RNA polymerase sigma factor,
                     sigma-70 family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_5314_0190"
                     /evalue="3.90E-30"
                     /identifier="TIGR02937"
                     /label="ctg1_5314"
                     /locus_tag="ctg1_5314"
                     /protein_end="173"
                     /protein_start="18"
                     /score="102.6"
                     /tool="antismash"
                     /translation="YSEIITRYHGKVSSILRKMLGHTPDAQDIVQEIFIKTYYHLPEYK
                     TNYDFSAWLYRIAANHCLDELRKRKRKQQLTTSEEIEPVDSHTPEVAFLNKEGQRLLRQ
                     RMMSVEEKYRIVLEMRYFESLSCEEISHRLSIPSSTVRTRLSRGKDKLREA"
     PFAM_domain     11725..11925
                     /aSDomain="Sigma70_r2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04542.16"
                     /description="Sigma-70 region 2"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_5314_0922"
                     /evalue="2.90E-18"
                     /label="ctg1_5314"
                     /locus_tag="ctg1_5314"
                     /protein_end="89"
                     /protein_start="22"
                     /score="65.5"
                     /tool="antismash"
                     /translation="ITRYHGKVSSILRKMLGHTPDAQDIVQEIFIKTYYHLPEYKTNYD
                     FSAWLYRIAANHCLDELRKRKR"
     PFAM_domain     12010..12168
                     /aSDomain="Sigma70_r4_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08281.14"
                     /description="Sigma-70, region 4"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_5314_0923"
                     /evalue="4.60E-12"
                     /label="ctg1_5314"
                     /locus_tag="ctg1_5314"
                     /protein_end="170"
                     /protein_start="117"
                     /score="45.5"
                     /tool="antismash"
                     /translation="RLLRQRMMSVEEKYRIVLEMRYFESLSCEEISHRLSIPSSTVRTR
                     LSRGKDKL"
     CDS             12213..13922
                     /locus_tag="ctg1_5315"
                     /transl_table=11
                     /translation="MKCLDKGQIALYLYDLLEPEEAEVIAAHLEECRHCQLKLKQELDE
                     LEDPEESLATDEPSDAVIQDIMASLPPYPIHVLKRSERQNIQKKIDWKKRSLDIVKKAT
                     IAVAGMAAVVYFGTLTSPSFATYVNDLYAATIKSQPKQTESSLFAEEASEDALIQRGLE
                     EGYNKKLDLKAVDNGMTLEVKEVMADTRDVRIIFGFKDKNGKQLEKLFRNFPLGDEDKL
                     NETYEIKITDEDGNVLETIDKYHLNYNKKESIGEKDEYLMVSRPISRYFTDVSKIPDKL
                     NIELSIKKLDKVDGNWSVTIPVDISKAKKETKIVPINEHFTAPNGEVINLKQVMVTPGQ
                     TEFVIENTEGSGSSPSLTYEVVDDKGTVLAAWSTLDLMSEFGEEPNPFFKNVSREYFVR
                     ATADRNVHFINFHSLPTNKNLTFRVGDNYDQVPSNFKQKLSIETLKTTPVTIKHEGSTL
                     TFSNFASEEITKTNPITSEKHKKLRSTIQLEATLAPGVIFLDSWEGADDKGKEYDFNFM
                     GSTTKDEKGNFVVKGILVDEMDAIPKELTLTIEEQVNRAKDMDWSVALPLKN"
     PFAM_domain     12504..12812
                     /aSDomain="DUF4179"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13786.8"
                     /description="Domain of unknown function (DUF4179)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_5315_0924"
                     /evalue="5.90E-17"
                     /label="ctg1_5315"
                     /locus_tag="ctg1_5315"
                     /protein_end="200"
                     /protein_start="97"
                     /score="62.0"
                     /tool="antismash"
                     /translation="DIVKKATIAVAGMAAVVYFGTLTSPSFATYVNDLYAATIKSQPKQ
                     TESSLFAEEASEDALIQRGLEEGYNKKLDLKAVDNGMTLEVKEVMADTRDVRIIFGFK"
     CDS             complement(13985..14680)
                     /locus_tag="ctg1_5316"
                     /transl_table=11
                     /translation="LIDYRGWRHTFKLDPDKTIDDEALEAICESGTDAIIVGGTYGVTY
                     DNTLELMSRLRRYAVPAVLEISSLDAVVPGFDSYLIPLVLNAGDPDWIFAPHVSGLQAF
                     GAYIHWDEIITEGYIIANPEAGVAELTKARPIADASQAKAYAQVATNICRLPIVYMEYS
                     GTYGDPAIVKAAKAGAGEAHLFYGGGIRNPEQAAEMAAIADTVVVGNVIYDDLAAALST
                     VKAVKGTRN"
     PFAM_domain     complement(14003..14674)
                     /aSDomain="PcrB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01884.19"
                     /description="PcrB family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_5316_0925"
                     /evalue="1.80E-70"
                     /label="ctg1_5316"
                     /locus_tag="ctg1_5316"
                     /protein_end="226"
                     /protein_start="2"
                     /score="237.0"
                     /tool="antismash"
                     /translation="DYRGWRHTFKLDPDKTIDDEALEAICESGTDAIIVGGTYGVTYDN
                     TLELMSRLRRYAVPAVLEISSLDAVVPGFDSYLIPLVLNAGDPDWIFAPHVSGLQAFGA
                     YIHWDEIITEGYIIANPEAGVAELTKARPIADASQAKAYAQVATNICRLPIVYMEYSGT
                     YGDPAIVKAAKAGAGEAHLFYGGGIRNPEQAAEMAAIADTVVVGNVIYDDLAAALSTVK
                     AV"
     aSDomain        complement(14012..14659)
                     /aSDomain="TIGR01768"
                     /aSTool="tigrfam"
                     /description="GGGP-family: geranylgeranylglyceryl phosphate
                     synthase family protein"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_5316_0191"
                     /evalue="1.40E-66"
                     /identifier="TIGR01768"
                     /label="ctg1_5316"
                     /locus_tag="ctg1_5316"
                     /protein_end="223"
                     /protein_start="7"
                     /score="222.2"
                     /tool="antismash"
                     /translation="RHTFKLDPDKTIDDEALEAICESGTDAIIVGGTYGVTYDNTLELM
                     SRLRRYAVPAVLEISSLDAVVPGFDSYLIPLVLNAGDPDWIFAPHVSGLQAFGAYIHWD
                     EIITEGYIIANPEAGVAELTKARPIADASQAKAYAQVATNICRLPIVYMEYSGTYGDPA
                     IVKAAKAGAGEAHLFYGGGIRNPEQAAEMAAIADTVVVGNVIYDDLAAALSTV"
     CDS             complement(14698..14988)
                     /locus_tag="ctg1_5317"
                     /transl_table=11
                     /translation="MQLEKLKGKGLEQLFEAVLSLETMEECYQFFDDLCTVNEMQSLAQ
                     RLEVARMLRKGFTYNQIEAETGASTATISRVKRCLNYGNDGYQMALERIGK"
     aSDomain        complement(14707..14970)
                     /aSDomain="TIGR02531"
                     /aSTool="tigrfam"
                     /description="yecD_yerC: TrpR homolog YerC/YecD"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_5317_0192"
                     /evalue="3.50E-47"
                     /identifier="TIGR02531"
                     /label="ctg1_5317"
                     /locus_tag="ctg1_5317"
                     /protein_end="94"
                     /protein_start="6"
                     /score="156.7"
                     /tool="antismash"
                     /translation="KGKGLEQLFEAVLSLETMEECYQFFDDLCTVNEMQSLAQRLEVAR
                     MLRKGFTYNQIEAETGASTATISRVKRCLNYGNDGYQMALERI"
     PFAM_domain     complement(14710..14961)
                     /aSDomain="Trp_repressor"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01371.21"
                     /description="Trp repressor protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_5317_0926"
                     /evalue="9.30E-35"
                     /label="ctg1_5317"
                     /locus_tag="ctg1_5317"
                     /protein_end="93"
                     /protein_start="9"
                     /score="118.8"
                     /tool="antismash"
                     /translation="GLEQLFEAVLSLETMEECYQFFDDLCTVNEMQSLAQRLEVARMLR
                     KGFTYNQIEAETGASTATISRVKRCLNYGNDGYQMALER"
     CDS             complement(15109..16164)
                     /locus_tag="ctg1_5318"
                     /transl_table=11
                     /translation="MKRTVKSSLMVLAFMLLTTACGQKPVDTQPSPQMPDPIVQTPPET
                     NQPIQYAYKAPMTGLGSHENLGSKRPIMVMINNAPPARPQTGINKADMIYEVLSEGEMT
                     RFLAIFQSQTPEVIGPVRSIRPYFIQIGTGFDAVLVHAGGSPDALETLARKDLSHLDEI
                     PNGQYFWREKFRKMPHNLYTKPELLEKAMQDKGMRQTAEVPHFTFLPEDAEIKEGEPAT
                     QVDLTFHSLNKAAFTYDAEQKKYMRFTAGKPHLDLSDKKQLSTTNLLVITAKHRVLDKE
                     GRLSVDVIGPGDGYLFQQGKARKVKWKRSNGVIRVYEDAALTQEAPLLPGNTWVAILPN
                     SPGLSKSLKFQ"
     PFAM_domain     complement(15160..15492)
                     /aSDomain="DUF3048_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF17479.4"
                     /description="Protein of unknown function (DUF3048)
                     C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_5318_0928"
                     /evalue="8.00E-25"
                     /label="ctg1_5318"
                     /locus_tag="ctg1_5318"
                     /protein_end="335"
                     /protein_start="224"
                     /score="87.5"
                     /tool="antismash"
                     /translation="DLTFHSLNKAAFTYDAEQKKYMRFTAGKPHLDLSDKKQLSTTNLL
                     VITAKHRVLDKEGRLSVDVIGPGDGYLFQQGKARKVKWKRSNGVIRVYEDAALTQEAPL
                     LPGNTWV"
     PFAM_domain     complement(15574..15996)
                     /aSDomain="DUF3048"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF11258.10"
                     /description="Protein of unknown function (DUF3048)
                     N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_5318_0927"
                     /evalue="1.60E-50"
                     /label="ctg1_5318"
                     /locus_tag="ctg1_5318"
                     /protein_end="197"
                     /protein_start="56"
                     /score="171.2"
                     /tool="antismash"
                     /translation="MTGLGSHENLGSKRPIMVMINNAPPARPQTGINKADMIYEVLSEG
                     EMTRFLAIFQSQTPEVIGPVRSIRPYFIQIGTGFDAVLVHAGGSPDALETLARKDLSHL
                     DEIPNGQYFWREKFRKMPHNLYTKPELLEKAMQDKGM"
     CDS             16345..17046
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 170.5; E-value: 6.7e-52)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_5319"
                     /transl_table=11
                     /translation="MNTPYLVYLVDDETNLLELLQSYLQSAGLQVKAFSSGKDVLPLLD
                     EETQPHLWILDIMMPDIDGYELLRLIREKSNVPIIFISARDQDVDKIIGLELGSDDYLA
                     KPFLPRELVIRAKKLLQRTYEKSNGTASSTQTFQDWVTVDPYMISEKGRQVKEGDELID
                     LTTKEFELIVYLLHNQGLALNREQILTSIWGEDYIGSDRAVDDLVKRIRKKMPKFPLET
                     VYGFGYRMTRL"
     PFAM_domain     16363..16689
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_5319_0929"
                     /evalue="1.80E-26"
                     /label="ctg1_5319"
                     /locus_tag="ctg1_5319"
                     /protein_end="115"
                     /protein_start="6"
                     /score="92.6"
                     /tool="antismash"
                     /translation="VYLVDDETNLLELLQSYLQSAGLQVKAFSSGKDVLPLLDEETQPH
                     LWILDIMMPDIDGYELLRLIREKSNVPIIFISARDQDVDKIIGLELGSDDYLAKPFLPR
                     ELVIR"
     PFAM_domain     16825..17034
                     /aSDomain="Trans_reg_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00486.30"
                     /description="Transcriptional regulatory protein, C
                     terminal"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_5319_0930"
                     /evalue="5.80E-19"
                     /label="ctg1_5319"
                     /locus_tag="ctg1_5319"
                     /protein_end="230"
                     /protein_start="160"
                     /score="68.0"
                     /tool="antismash"
                     /translation="LIDLTTKEFELIVYLLHNQGLALNREQILTSIWGEDYIGSDRAVD
                     DLVKRIRKKMPKFPLETVYGFGYRM"
     CDS             17043..18458
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 150.9; E-value: 1.1e-45)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_5320"
                     /transl_table=11
                     /translation="MSKFRLKNLPISRQILILFMILTSVLGVGLGIGYPMAVKQYLVSN
                     TYSLLEEEFYTLSQHISFNEHNELLPVPAAAPYFLQLLLQRYEYSFDMIVYAENGQELG
                     RRSNTNGRIPYEDTKELFLKAATYPSQKLQHGSLDRGAESYLFVSKKMDYHGFPYYMVL
                     FSKEQELNQINSILTRQFLLVFGLLLLVSWLLAVWFSGYLSRPLRTLEELCKKIARRQF
                     DIPLAMDRGDEIGQLARSFDMMKNQLKEYDESQQHFVQNISHELKTPIMAIQGYTQGLI
                     EGVFQGPQAEKGLSIIMEESKRLEKVVGQLLYITKIESVSQMMQVDRVDLSEMMHLLKQ
                     RLSVLNPQIEWELNLAADLIVEGDGEQLSTAFVNIMENQLRYAKSRLTITGRHAGKSVV
                     VAISNDGPPIEEALLPNLFQRFRKGKSGKHGLGLAIARAVLEAHKGTIDARNDPDGPCF
                     TMIVPVEFKGRLN"
     PFAM_domain     17634..17789
                     /aSDomain="HAMP"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00672.27"
                     /description="HAMP domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_5320_0931"
                     /evalue="6.10E-11"
                     /label="ctg1_5320"
                     /locus_tag="ctg1_5320"
                     /protein_end="249"
                     /protein_start="197"
                     /score="42.6"
                     /tool="antismash"
                     /translation="WFSGYLSRPLRTLEELCKKIARRQFDIPLAMDRGDEIGQLARSFD
                     MMKNQLK"
     PFAM_domain     17802..17999
                     /aSDomain="HisKA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00512.27"
                     /description="His Kinase A (phospho-acceptor) domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_5320_0932"
                     /evalue="2.00E-11"
                     /label="ctg1_5320"
                     /locus_tag="ctg1_5320"
                     /protein_end="319"
                     /protein_start="253"
                     /score="43.9"
                     /tool="antismash"
                     /translation="SQQHFVQNISHELKTPIMAIQGYTQGLIEGVFQGPQAEKGLSIIM
                     EESKRLEKVVGQLLYITKIES"
     PFAM_domain     18129..18434
                     /aSDomain="HATPase_c"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02518.28"
                     /description="Histidine kinase-, DNA gyrase B-, and
                     HSP90-like ATPase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_5320_0933"
                     /evalue="3.40E-11"
                     /label="ctg1_5320"
                     /locus_tag="ctg1_5320"
                     /protein_end="464"
                     /protein_start="362"
                     /score="43.7"
                     /tool="antismash"
                     /translation="GDGEQLSTAFVNIMENQLRYAKSRLTITGRHAGKSVVVAISNDGP
                     PIEEALLPNLFQRFRKGKSGKHGLGLAIARAVLEAHKGTIDARNDPDGPCFTMIVPV"
     CDS             complement(18492..19334)
                     /locus_tag="ctg1_5321"
                     /transl_table=11
                     /translation="MLTAKHDNVNRESIEGEISLLKLRTGHEQRQLLGQISLEDSYILY
                     GNMYVRTDRSVVVTDSVQGEVTVIGSYLKGMPFHAFSLHVVEGEKNYEVEPILSYMKEV
                     LDGSLSDGQKGVIALAEPLLTRVQIPNILATRTMRLMKLTDPERLLPVGESRILELSEA
                     QIVEDMAAELGMISFRAEEVAEMPHIALFSEDGEPMAVAGFHVYDEAYVEIGNIGTSVH
                     HWQKGLGTQISSDISRIGLEKSANVYLMVFADNPTAMHVYEKLGFVTVSSYAFIEFVL"
     PFAM_domain     complement(18534..18773)
                     /aSDomain="Acetyltransf_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00583.27"
                     /description="Acetyltransferase (GNAT) family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_5321_0934"
                     /evalue="2.20E-08"
                     /label="ctg1_5321"
                     /locus_tag="ctg1_5321"
                     /protein_end="267"
                     /protein_start="187"
                     /score="34.5"
                     /tool="antismash"
                     /translation="HIALFSEDGEPMAVAGFHVYDEAYVEIGNIGTSVHHWQKGLGTQI
                     SSDISRIGLEKSANVYLMVFADNPTAMHVYEKLGF"
     CDS             19405..20904
                     /locus_tag="ctg1_5322"
                     /transl_table=11
                     /translation="VAFYYTEPSRTFNEFLLLPNLTTKECTPNNVDLSTPITKYKKGEK
                     PAITLNIPFSSAVMQAVSDHHMAVALARCGGISFIFGSQSIESQATMVRKAKGYKAGFV
                     VSRSNLTPSHTLKDILELKEATGHSTVAITEDGTAKGKLLGIVTGRDYRISRDSLDKLV
                     SDIMTPFSKLIYGKSGITLSEANDLIWEHKLNCLPIVDENQNLDFLVFRKDYDSRKNNP
                     LSLLDANKSYIVGAGINTKDYKERVPALVEAGVDILVIDSSDGFSEWQRETVQYVKENF
                     NVPIGAGNVVDKEGFRYLVESGADFIKVGIGGGSICITREQKGIGRGQASSLIEVAAAR
                     DEYFKETGIYVPLCSDGGIVHDYHVTLALAMGADFVMLGRYFARFDESPTKKVKIGNNF
                     VKEYWGEGSNRARNWQRYDTGGKSSLVFEEGVDSYVPYAGSLRENMDRTLSKIKSTMCN
                     CGSLSISELQQKARITVISATSLVEGGAHDVILKESSMAAE"
     PFAM_domain     19435..20865
                     /aSDomain="IMPDH"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00478.27"
                     /description="IMP dehydrogenase / GMP reductase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_5322_0935"
                     /evalue="1.30E-108"
                     /label="ctg1_5322"
                     /locus_tag="ctg1_5322"
                     /protein_end="487"
                     /protein_start="10"
                     /score="363.1"
                     /tool="antismash"
                     /translation="TFNEFLLLPNLTTKECTPNNVDLSTPITKYKKGEKPAITLNIPFS
                     SAVMQAVSDHHMAVALARCGGISFIFGSQSIESQATMVRKAKGYKAGFVVSRSNLTPSH
                     TLKDILELKEATGHSTVAITEDGTAKGKLLGIVTGRDYRISRDSLDKLVSDIMTPFSKL
                     IYGKSGITLSEANDLIWEHKLNCLPIVDENQNLDFLVFRKDYDSRKNNPLSLLDANKSY
                     IVGAGINTKDYKERVPALVEAGVDILVIDSSDGFSEWQRETVQYVKENFNVPIGAGNVV
                     DKEGFRYLVESGADFIKVGIGGGSICITREQKGIGRGQASSLIEVAAARDEYFKETGIY
                     VPLCSDGGIVHDYHVTLALAMGADFVMLGRYFARFDESPTKKVKIGNNFVKEYWGEGSN
                     RARNWQRYDTGGKSSLVFEEGVDSYVPYAGSLRENMDRTLSKIKSTMCNCGSLSISELQ
                     QKARITVISATSLVEGGAH"
ORIGIN
        1 gctgccaata cgggctgact ccgataaacg taagtccgta gttgatgacg ccaaaaataa
       61 ggacacccgc aagcacacct ggaacggtac caattccgcc agacgtcgag actcccccta
      121 ccacacaggc tgcaatggcg tccagctcgt acatgttgcc gtagttgttc gtcgcgccac
      181 ctgtccgggc tgcctccaga actcctccga gtccatacag ggcaccagca atggcataga
      241 taatcatgag gttgaaagcg acgttgatcc cggaaacagt tgcggcctgc atgttgcctc
      301 cgatggcgta catgttttta ccaagccgtg ttttgttgaa gattacccag acgatgaagg
      361 caaccatgat cgcaatgatg acaatatacg gaatcgaata cgggccactc gggccgatgt
      421 accctgtccc aagctgattg aagtcactcc gcagtccagc gattggctgc gattgattgg
      481 gctccatatc aaaatagatg gagttgaacc cgtatacaat gaccatcatg cccaacgtag
      541 cgataaaagg tggcacacta aaacgagaca caataatgcc gttgatcaga ccaaccagca
      601 agcccgcagc gattgcgatg agaatgggga taagcaacgg caaatcgggt aaatccggga
      661 aaaacctccg cggatagtct tggctttgca gcattgaggc agagatgaca gccgtcaatc
      721 cgaccactcg ccccgcggaa agatccgttc cgcctgtaat aagaacaaac gcagcaccca
      781 aggcaataat agcgcgagtg gaggattgca ccaaaatatc ccgaagcgtt gtaatggaaa
      841 gaaaattagg gtcgtaaatc gcaattcccg cgatcaacaa aaccagaacg atatagatgg
      901 cgttttgcgt aacaaagcct tgcacctgtt tagcagacaa ctgagacatg cctgttcgcc
      961 tcctttctca tgcaagatgt ttggtagcca gccgcataat ctcttcttcg gttgccgctg
     1021 tacccgacaa aaaaccggag agcctaccct cgcacatgac catgattcga tctgacattc
     1081 caagcaactc tggcatttcc gaggaaatca taatgatccc ttttccttga ctcgccagtt
     1141 ccgcgatgat ggtatagatt tcgtatttgg cgccaacatc gactccacgc gtaggttcgt
     1201 ccagcaataa aatatccgga tcagtcaaaa gccacctcgc caacagaacc ttttgctgat
     1261 tgccccctga caggtttttg atcaaggctt tcatagaggg agtcttgacg cggagcatct
     1321 cgatgcttcg gctgacatcc gctcttcgct tgcgctcatt gaggagcaga aaaggtgttt
     1381 ggtaactggc caaattcgcg atgaccgtat tttccagaat cgataagaca ggaatgatgc
     1441 cagtgactcg ccgctcctcc gtcaagagcg ccattttgtg cttcttcgca tccttcggtg
     1501 atttgatccg cacctcctga ccgttgatcg acacttttcc tgctgacact gcgcgcaatc
     1561 caaacaatgc ctcaatcagc tctgttcgtt gtgcgcccac gagaccgcct acgcccaaga
     1621 tttcgccttt gcgcaattca aacgacacgt gctgaaatga ctgggaaaat ggagagctca
     1681 gtccttctac ctttaaaatc ggttcccctg gcgaattcga tcgactcggg aaacgctgcg
     1741 tcaggtcccg tccaaccatt ttcgagatga tcaggtctgt cgtcagctcg gctgcccgcc
     1801 atgttccaat gagcttgcca tcgcgcatga tcgtcacgtc atccgcaatc cgtaaaattt
     1861 cttccatctt gtgcgaaata tagatgatgg cgacacctct gctcttcagt tcgcggatga
     1921 tcgcaaatag ctgctccacc tcgtttcccg tcagtgaaga cgtcggttcg tccataataa
     1981 tcactttgga ttggtaggaa acagctttgg ctatttcaag cgactgtacc ttggatacag
     2041 acaaatcacg gacaacagcg tgcggattca aatccattcc cagatcagca aacagcttct
     2101 tcgtatccgc gagcattctt gtctcatcca caaacggaaa aggaccgatt cttttgaccg
     2161 gaaaacgacc tagccaaatg ttttccatga cattgcgaaa gggcaccgga tgcagctctt
     2221 gatgaatcat ggagatgcca tgggccagcg cgtcctttga gctgctcatc gtcacctgct
     2281 cattgtttag caggatttct cccgcatctg gtcgatatat tccgaagaga cacttcatca
     2341 gggtcgattt gcctgcccca ttctctccca tcagtgcatg aacagttccg ggacggactt
     2401 ttagcgtgac atcgtcgagt gccttgaccc ctggaaattc tttatgaatg tggttcattt
     2461 ccaacaaaaa tgcatgctga gccatgcgag tgccctcctt tttgcaaaat catccccatc
     2521 accgaaacag gagagtcgga ttcgtctctt caccgactct cctgcttttt atttcgcgtc
     2581 gttcatgttt tccttggtga tttttttgta gggcacccac acgtacttcc catccgtaat
     2641 gtcaaagcct gtagaatctt tcgttggcgt ttcacccttc gccaaagacg ccgcgatgct
     2701 aagggtggct tttccttggt tattcgcatc gttgaggacc gttccgagca aggttcccgc
     2761 ctccaactcc ttcaacgcag gtgctgtggc gtccacgcca acaacaggca tgtacttgcc
     2821 attcgcaaaa tagccagatg ccttcagcgc ttcgattgcc cccagtgcca tatcgtcgtt
     2881 gttggcaaga acggcttcga tcttgtcacc ggaagctgcg aggaaggctg ccatcttttc
     2941 ctgccctttt acgcgatccc acatggccgt atcttccgcg accttctcta ctttaatccc
     3001 tgcatcttca atcgccttca ccgaaaactt cgtccgcagc tcagcatcct gatgccctgg
     3061 ctcgcctttt aacatgacat attggaggac accatccttg tttttatctg cttccggatt
     3121 tgccttccag taatcgacga tcagctcgcc ggagattgtg ccggattcct ccgcttttgc
     3181 tcccacgtag taaaccttat cccacttctg catatcctct ggcatcggct cacggttgaa
     3241 gaagacgacg ggaatattgg cttgtttcgc cttgtcgata aggacgccag cagctgtgcg
     3301 atccaccgga ttgatggcga gggcatttac ctttttgtta atgaacaaat ccactttgtc
     3361 attttgcgta ggctgggcat tttggctgtc tacaatgtcc acttccgctt tgccttctgc
     3421 ggctttcgaa atcgcattgc gcactcctgt catgaacgta tcatcgaact tgtagatggc
     3481 gactccgatt ttgggattcc ccgcaggaga cgagcctccc ccggacgctg ccggctgcga
     3541 accgccagat tgtgagcatc caaccaccga gagtgtaaca gcggctacca gtgtagtggc
     3601 aatcagcttt ctcattcgat aatccccctt tatcccctat gtttacatct gatatacacc
     3661 aaatgtaagc gttttcccaa gtgtgttcca tcgaaaatcc tgcgcatttc tatcaaaatt
     3721 ctcatctgtt ttttcggtgg cctattttac gaaggggaag aggagctttt gattctccga
     3781 ccaaaacata ttctcccgat cgattgcttt tgttccggtg tcgaccagac tgggcactgc
     3841 ttctccgttg ctcgcttcga ctgcgtactt gacgccgaga tatcccatcg atagcggctt
     3901 ctggatgatc gtcgcggaga tgatcccttc ctgcaaatac tccagcactt ccggtggact
     3961 gtcgattgct acgattttga ctttgtcccg cagtccactg ttttccattt cctcggccac
     4021 accgatcgct gtactggcat cgagtgcaat cacccctttc aactgcggat gcttgcggat
     4081 cagttcgcgc gtccactcac cgatctgctt tttatccaag ggaacatttt cgttggcaat
     4141 caattcaacc tgcgtttccc gtgggagcaa atcgaggacg ccctgttctc ttcgtttggc
     4201 atttgccttt acccgatctg tgccgagcaa tgcgatttgt ccttttttct cgatcaggta
     4261 catcattttt tcgaatgcct tcatgcccat atcgtagtta tccgtcccaa tgtagctttt
     4321 gacggctgaa tcttttccga cggtgtcgag tacaaggatc gggatggccc tctccctagc
     4381 cagcttgata gcttctcgca aaacgtgttc gtcactaggt gccaccacga ttgtctcgga
     4441 gccatctgcg attgcctgct gcaccagctc catttgcctg tgggcatcct cctcatagtc
     4501 tggcgcgtaa aaattcaggt ttcgctcata ttccttggca gccatctccg ccccgagctt
     4561 gaccgttcgc caataatcgc cgtgcttcat acggacgatc agcgccactg tctttttctt
     4621 gcctacttcc ccatctgtaa gcggagcact gcatgagcaa aaaagcgtca ccactgccaa
     4681 aacgaccagt ccgtatacgc tcaaacgttt caccgctgcc gtcctcataa tcgatctcgc
     4741 tcctctgcaa cctggcgcgg aatccataca cgcacaacgg tcccctcttc ctgttcgctc
     4801 gcaatttcca aaccgtactg ttccccgaac gtcaagcgga tgcgctcttg cacgttttgt
     4861 atcccaacgc ccgagccttc ttcgcttcta taaaagccgg cttttacttg tgcaagaaca
     4921 tcaggggaca tgcccaagcc attgtcgctt acctgaagta acaccttacc gtcgatgagt
     4981 gctgcaaata tgcgaatcca gcccggatca gccaaatgct caatcccgtg gtagatagcg
     5041 ttttccacaa tcggctggag cagtaacttc agcgtcaggc aattgagcac ctcatcctca
     5101 ttctcgacca cgatctcgta ctcaaatttt tgcttgtacc tcattttttg aataataaga
     5161 taatgacgca catgctccag ctcttcccgc accgtgataa tgttcttgcc tctgctcagg
     5221 ctaatccgaa acagctttga caacgaagta atcgtggtga tgacatcctc gttttttccg
     5281 ttgccgacca ttctgaccac agagttcaac gtgttgtaca gaaaatgcgg attgatctgt
     5341 gcctgtagca cctccagctc gctttttcgt ttggcttcct gttcccgaat gatctggtgc
     5401 atcaattccc tgaccttcgc gaccatcaga tgaaaacgca aggaaagctg ttcgacctca
     5461 tggcttcccc ggatcggttc actctctgaa aagtctccct gctccacctt ttccatggat
     5521 cgctccagca gcttgatcgg tcgtgatatt ttcgcagaga gatagtacag cacgaacaac
     5581 acaatgacaa tcacaaagat gagcagccaa aaaatgaagc gactgatttc ttttttggtc
     5641 gtcacaatct cgtccatata ggaaacccca atgattttcc agcctagctg atcgatcgtc
     5701 ttgatggtga tcaaacgcgc ttcgtcctgt gtctcttcta catagctgcc ataggaatgc
     5761 ttcagcggca aggaacggtt ttcatttttc aatccggcgt aaatcaactg ctgctgcgga
     5821 tggtagacga tgttcccgac caaatcgatg atgtagacgt accccttttt ccccaagccc
     5881 actctctggc acaattcatc gatctctttg aaattcacat caactaaaag tacggccgga
     5941 atttctccgt caggtccgtg gagaagaatt tcccgactca tcgaaacgac ccaggtgtac
     6001 tctcctttaa acaagttctg gatatgcgga agtgaaaagg acaggttcgt cgggtcctcg
     6061 atcgcctttt ggaaccagct ctgttcggtc aaacgagtgt ttttcctcaa tactttggaa
     6121 ggagttgtgg ccaacaacgt tccgtctcgt gtaaaaaccg cgatggagac gatgtccttt
     6181 ctcgtttcta cgattgtctc aagctgttcg ttcagctcgt ctgccgtgag tcccttgctt
     6241 cttctgatct tgtcatcaac gagttcgaaa atttgcgtca tcccattcat atagctctcc
     6301 agattgtatt tcacctgctc caggatttgc tgcgtgtgca gatacgcgtt ttgctctgcc
     6361 gtctgcgcaa attttccgta cagcatcacc ccgacaaaca gcatgacgag taccgtcacg
     6421 agtgtaaagg aggtggtaat gataaattga atgcctttga ccttgatcac cacaagcaat
     6481 ctcttcatgg gttaaccttc ctgctcgctc tggcttcggt actctttggc ggacatgcct
     6541 gcatacttgc gaaagctgaa gctaaagtaa ttgggatcgg tatatcctac tttctccgcg
     6601 atttcaaagg acttcaaatc ggtcgtccgc aaaagctcct tggccttttc catgcgtaat
     6661 gacaggagat aggtcacaaa cgttgtcttc gtttctttct tgaaaatact gctaaaataa
     6721 ccgaggctga tgtgcagatg atcgcacacc ttgtggatgg atatgtcggg agaatgataa
     6781 tgcgcgtggg tgtagtccaa tgcctgcgta atcaatcgcc tgtacgtcgt ttgccgtccg
     6841 tttgcgatac tcgccatgag gcgctcacaa atatctgtga tctgttcgcg ggcatcctcc
     6901 ataccggtaa aagtcgtcat gacctgcaag agatagcgtt gtccgccaaa cagttgatcc
     6961 atgtcaactt cggcacgatg ggcagtcttc aatatggtcg tcataatctc caacaaataa
     7021 attcggtagt cctcaatgga taccggaaca cgtgccactt gatcaaacaa ttcatcaatc
     7081 acgttccgaa gctccgcact cgtccccatt ttgatgcacc gaaccaattc atgctccctt
     7141 ctctcatcga ggcgtatctg ctcactcgct tgcttttcca cgtcattgat cacaatcatc
     7201 ctgttgcagc cgaggatgct tctgtaatcg agtgcctgca tggcgtcctc atacgagtaa
     7261 gggagtgccg ctacatctgt cacgacgttg ccgattccga ttgttaccgt gatgctcata
     7321 tatttttcaa tcgttcgcct gatttcttcg gcgatatttt gtgtttgcac ttcgattcgt
     7381 tgcgtgtcgt ctgcttttgt tcgcatgagc agcacaacct gatcttcatg gagaaaaacg
     7441 atgcccgcct gtttgcctgc gttcagctgt tcttctgcga tatttttcac agcgaaaaga
     7501 aacagctgct gctcctcctg cttgggctgg tctacacaga tgaccgccac gagatattcg
     7561 ggactcctga gctctattcc gtattcgcag gcttttgaat aaacatcgtg ctgtacgagc
     7621 tgacgactca gcaaagatga taaaaaaacc tcccgcaaaa ccggcaagct ttttcgatag
     7681 ctatcgcgca gcagctgaac gttttcccga tgagccgcct cctcgtccat ccgtcgcttg
     7741 accttgtcca gcgcttccaa cagctcactc gcggaaaacg gcttgagcac atattcatca
     7801 atttgcagct tcacggcctt ttgcgcgtac tcgaactcat caaacccagt caggataatg
     7861 atgcgaatgg cagggtaatc acgcccgata gactccgcca gctgaagtcc gttcataaag
     7921 ggcatcttga tgtcggttac aacgacgtcc ggtcgaagtc tctctaccaa ctccaatgcc
     7981 tctctgccgt tttctgcttt ggcaaccacc tcgtatccgt agctatgcca gtcaatttct
     8041 tggctaaccc cttctcttac atcttcttcg tcatctacca atatcagctt atacatagac
     8101 acctcccgct gttgtacttg tacaacggga ggcgattgtt ttcctgccaa tggaatggta
     8161 tggcgctacc acgtcttatt cagatcatct gcatagaaca gaatcgcttt ttgataggcc
     8221 aaaatcgcag gatcgcttga ggtttccgcg aggtttttca ggagaagagt catggcttcg
     8281 tgatgcttac ctagattgta atacgccatg gaaagaaaaa tcggaaagga acggtcgcag
     8341 gggaactgtt gcatcccctt cgcgagcgta gctgctgcct gctcgtattg tcccagcgtg
     8401 cgatacgtac tgcccagacc cagtaatgcc ccttgcaggt cgtcttcgac agacagtccg
     8461 agctcaatcg ctttctcgta aaagggaacg gcttccttct ccaatccggc tgcatcgtgg
     8521 caccatgcac attgataatg ggcaacagga tcagtcgggg attggctgac gagctgaagg
     8581 gcaagctgga tcgcttcgtc cagatgccct tcttttcgca gctgaatgat attttggatc
     8641 atcgggttca tgtgagcact tcctttgcct gggtatctct cttcccccta gcgtaacagg
     8701 gcagcttggc aaggtgaaga cgcaaattat gtaccctgca aggattttgt ccgctctctt
     8761 tcgcttctcc gttgtcgata ggctctcatc cacgaccagc ccaaaatgag aaacggaacc
     8821 agaaccaaca ggatcaacag gatgccgtcc caaaactccc acgagtgaag cgaagcgttt
     8881 ttcatatcgt ctgcgatgat ccaaatgaaa tcaaccgcca tgcgcagctg atactggaca
     8941 aagaaccaga ttccccacac cgatccgatc aagtagaccc agctatacca gcggatgact
     9001 cttttctcat ggtcggctac gtactcccat tcctcctgct catcctgcgt caaggaacgg
     9061 aatttcgctt ttagaaacag gcgtgtattc accatcaaat tggagcattg gaacttggtt
     9121 gccaatacgt aatacaagtc ggtctgcatg aaaaccatga actgaaaggc caaagccatc
     9181 agcaggatca cattcagcat acgaatgaat gcttccatga agggcacaag tgtcagccag
     9241 ccttgatcat tggcaaacaa cagaatgaca ccgatcccca taaacatcgc atcccaggac
     9301 attcccgcca aaaacgccct gtatctgcgc tgtggatcaa cgagaacaat attggacata
     9361 ttcgtctcag ctacggcaaa aacaagtcga tgtcccagac cgatacgact gccgatcccc
     9421 aatgatcggg ccgccatcaa gtgggccatt tcatggaaaa acagaaaaac ccatgtagcc
     9481 acgaaagaaa ccactaccga aaccgtcacg gaagaagaaa caaaaatatc ggaatagacc
     9541 gggatatact tgcccgtaaa cacacaaatc aaaagacctg tgaaaaataa gataccgtat
     9601 aatccaaagg caacacggtt aaagaaaaac tgacccgtac cctgcttgat ccaagagaaa
     9661 tgatccacaa ccggcactgg ctcgttgaca acttctccat ctgccatgta cacaaattga
     9721 taggaaccaa ttaaatcctg cgcaaagtcg agcacatcca ccggttcgcc taaccgttct
     9781 tccatgattg tcgctacttc attgatgctc ttcccttcat ccagcatatc gatgatctcg
     9841 acaccaatgg ccggaagcac aatgaaattg ctgatatccg ttcggccaat gaggatctct
     9901 tcctcgtttt ccgcccggcg cgcaagcggg tgcatcttga gaatgctatc tcccgagata
     9961 ttcacttaca gacaccttcc tctcttacag gaacgactcc ttactttgcg agcacttctt
    10021 ttcgcttgat atgaaaaatc ggctccgttc cgctgcctct tccacaagtc gggcattcgg
    10081 cttcatttcg ctcccactca aaaaacacac tcttttccaa cgtattaaag tcgaaaatga
    10141 taaatttgcc cgctgattgt accggagcga ttcctgtcaa atacctgatt gcatcggaag
    10201 ccatcattcc cgtaatcatc atggtattgg gtgcaatcgt ggcagtaggc aggataaagt
    10261 tggtatcgag cagcctttgg atcaactgcg gatagtcttc gatctgtctg gaacgatgca
    10321 aatgcatgca gtcgatacag cccgtctttc caggttctac cataaagaac tgtccttcga
    10381 tgaggttgaa tcccccagca atgaacggga tttgcagctt agcgcaggca tgattcaccc
    10441 atctctgcaa aaagaaaaag ggctgatcgg ctgcgagcat cacgaggtca cttccggcaa
    10501 taacccgctc cacgtcttcg ctggacttga tttgcagcgt ctccgtttca atcaatacct
    10561 cagaatgaag ccttccgatg aaatcacgtg ccgcttccac cttcagccga ccaatatcct
    10621 tttcgttaaa gaccatttgt cggttcaaat tgctgagctc cactctatca aaatccacga
    10681 gcttgatatg ctggattccc gctcctacca gattgaccag tagcgtagag ccaaaggcac
    10741 ccattcccag gatcgtcact ttttttctac ttacctgttc ctgtagctcg ctaggacttt
    10801 gattgagatc agtgaacaag gagaagtagc ggatattcgc tttatacctt tccttttgtt
    10861 ccgaagtcag aacggaagcc tcttccttcg cctgatccat caggaagccc aaggcactga
    10921 gtgattccac tgcttccact atttcttcat acgtaatttc agggtaatca acagccaata
    10981 atgtatgtat ttcaccgaca gtacgagtgc catccatcag tttgatcatc ttgcggatgg
    11041 acccattctc gtcttccaat tcgaaggtat agccaggcgc ctctcccaag cggatcatct
    11101 gctctgtcac ttcatagacg ggatgcactg gtttaaataa aggacgacgt tccataatac
    11161 aaaacacctc ccaatagtgg ggttcgctaa cccggctcat tttagatgaa aaaagggaat
    11221 agctcgtgtg ctattccccc tcttcttaag agaattaagc tgctactgca gtagtgcgaa
    11281 cgctttcaac ttttttcgct tggattttca tggatagttc cccctctctt cattcaaaaa
    11341 ttaagacaag ttcattatat ttcatgaatt tacagaattc tacaaatatt agtaaaaaat
    11401 tatatatttt ggtaatattc tactatttat ttcgtaagca ataggatttt ccttccaaat
    11461 tctatccaaa atattacaaa tccttctttg ccggaaatat ttactagtct ttttggaaaa
    11521 tactcctgaa tttgggacac tttcattttg ggattcgtag tactaggatg taatagggaa
    11581 atttcaccaa gatcactttt gtttgatcaa aaaaggaaaa gctgcgcagc gagccttttt
    11641 tgcctagggg gagcacaaat ggaggaagat cgagtgatca tcgggcgggt cttgcaagga
    11701 aacaaagact cctactccga gatcattacc agataccacg gaaaagtaag ttccattctt
    11761 cgtaaaatgt tgggacatac acctgatgca caagatatcg tgcaggaaat tttcatcaag
    11821 acgtattacc atttaccaga atataaaaca aactacgatt tttctgcatg gttgtaccgg
    11881 atagcagcta accactgtct ggacgagctg cgcaagcgca agcggaagca gcagctcacc
    11941 accagcgaag aaatagaacc agtggatagc catacgccgg aggttgcctt tctgaataag
    12001 gagggtcagc gcctgttgcg tcaaaggatg atgtccgtcg aagaaaagta tcggatcgtc
    12061 ctcgaaatgc gctacttcga atcattgagt tgtgaagaaa tcagccatcg actttcgatt
    12121 ccgtcgagta ctgttcggac gcgtctgtct cgtggaaaag acaagttaag ggaagcaatc
    12181 gggcatgcag ggcaaggggg ggactttcat ctatgaaatg cttagataaa ggacaaattg
    12241 ctttgtatct atacgacctt cttgagccag aagaagccga ggtcatagca gctcatttgg
    12301 aagaatgccg tcattgtcag ttgaagttga agcaggagct ggacgagctg gaagatccgg
    12361 aagaatcgct agcgacagat gagccatccg atgctgtcat ccaagacatc atggctagtc
    12421 ttccccctta ccccatacac gtcctgaaac gatcagagag acaaaacata cagaagaaaa
    12481 tcgattggaa aaaaaggagc ctggatatcg tgaaaaaagc aaccatcgcc gtagcaggaa
    12541 tggcagcagt cgtctatttt ggaacactga cttcaccatc ttttgcgact tatgtaaatg
    12601 acttgtatgc cgctaccata aaatcacagc cgaagcagac agagagcagc ttgtttgcag
    12661 aagaagcgtc cgaggacgct ctcatccagc gcggacttga agaaggatat aacaagaagc
    12721 ttgatttgaa agccgtcgac aacggaatga cgctggaagt aaaagaagtc atggcagaca
    12781 cgagggatgt ccggattatt ttcggcttca aggataagaa tggcaagcag cttgaaaagt
    12841 tgttccggaa tttcccactg ggagatgaag ataaactgaa cgaaacctat gaaatcaaaa
    12901 tcacagacga agatggaaac gttcttgaga caattgataa gtaccatctt aattataaca
    12961 agaaggaaag catcggcgaa aaagatgagt acttgatggt cagccgaccg attagcagat
    13021 attttacaga tgtcagcaag attcctgaca aactgaacat cgagcttagc atcaagaagc
    13081 tggacaaagt tgacggaaat tggagcgtga cgattcctgt tgatatttcc aaagccaaaa
    13141 aagaaacaaa aattgtaccg attaacgagc attttaccgc tcccaatggc gaagtgatta
    13201 atctgaagca agtaatggtg acacctggcc aaacggaatt cgttatcgag aatacggaag
    13261 gaagtggtag ttccccatcc ttaacttatg aagtggtgga cgacaaggga actgtactcg
    13321 cagcttggag cactctggac ctaatgagtg aatttgggga agagccgaat ccatttttca
    13381 aaaatgtaag cagggagtat ttcgttcgtg caaccgctga cagaaatgtt cacttcatca
    13441 actttcattc cttgccaacg aataaaaatc taacctttag agtgggtgat aattacgatc
    13501 aggttccttc gaattttaag caaaagctgt ccattgagac actgaaaacc acgcctgtaa
    13561 cgataaagca tgaaggaagc acactaacct tctcaaactt tgcttcagaa gagataacga
    13621 aaacaaaccc aatcacttct gaaaaacaca aaaagctgcg tagtacaata cagctagagg
    13681 caactttggc accgggtgtg atctttttag actcctggga gggtgctgat gacaagggca
    13741 aagaatacga ttttaatttc atgggctcca caacaaaaga tgaaaaaggt aattttgtcg
    13801 tgaaaggtat actcgtagat gaaatggacg caatcccgaa agagctgacg cttacgatcg
    13861 aggaacaagt gaacagagca aaagatatgg attggagcgt agcacttcca ctgaagaact
    13921 aacgcaaaaa taaaaccacc actcccaatg aaactgtaac agctcatggg agtggtggtc
    13981 ttttttagtt tcgggttcct tttacagcct tcacagtaga aagcgcagca gctaaatcat
    14041 cataaatgac attcccaacg acaaccgtat ctgcaatcgc agccatttct gccgcttgct
    14101 ccgggttacg aatccctccg ccataaaaga ggtgggcttc gcccgcgcct gctttggctg
    14161 ccttgacgat cgccggatcg ccgtatgtac cgctgtactc catgtagaca atcggcaatc
    14221 ggcaaatgtt cgtcgctacc tgtgcgtacg ctttggcctg cgaggcatcc gcaatcggac
    14281 gtgctttcgt cagctctgct acgcccgctt ctggattggc gatgatatat ccttctgtaa
    14341 tgatttcatc ccaatgaata taagcaccaa acgcttgaag ccccgataca tgcggagcaa
    14401 aaatccagtc tggatcgcca gcgttcagta cgagcgggat caagtacgaa tcaaatcccg
    14461 gcacaaccgc atccagcgag gaaatctcca agacagccgg tactgcgtaa cgacgcaatc
    14521 gcgacatcaa ttcgagcgta ttgtcatagg tcacaccgta cgtaccgcct acaatgatcg
    14581 catctgttcc ggactcgcaa atcgcctcca aggcctcgtc atcgattgtt ttatccgggt
    14641 ctagtttaaa tgtatggcgc cagccacgat agtcaatcaa cgttgcctgc ctcctagcta
    14701 ttttccgatc cgctcgagcg ccatctggta tccgtcattt ccatagttca aacagcgttt
    14761 gacgcgggaa atggtcgccg tacttgcgcc ggtctctgct tcaatctgat tgtaagtaaa
    14821 gcctttgcgg agcattctcg ccacttccag gcgctgtgcg agtgactgca tttcgttcac
    14881 tgtgcacaga tcgtcaaaaa actgatagca ctcttccatc gtttccaggg aaagaactgc
    14941 ttcaaacaac tgttcgaggc ctttcccttt taatttttcc aattgcatgt ctgtcacctc
    15001 tgttatatag tccgtctttt cgagcggttt ctcactgtac aatttttaag cactaaagct
    15061 tcaacaatta tcttagaaga aaccgccttc atccgcaagc cctaatcctt actggaactt
    15121 gagcgacttc gacagacccg gtgagttcgg caatatggcc acccatgtat ttcctggcaa
    15181 aagcggtgct tcttgcgtca gagccgcgtc ctcatagaca cggatgacac cattgctacg
    15241 cttccatttg accttgcgcg cttttccttg ctggaataaa taaccgtccc ccggaccaat
    15301 tacatcgacc gatagacgcc cttctttatc cagcacacgg tgtttggcag tgatgaccaa
    15361 cagattggtc gtggacaact gtttcttgtc gctcaagtcc aaatgcggct tgcctgctgt
    15421 gaagcgcatg tatttctttt gctcggcatc atatgtaaaa gcagctttat tcaatgagtg
    15481 gaacgtcaga tctacctgtg tagcaggctc gccttccttg atctcggcat cctccggcag
    15541 gaacgtgaag tgaggcacct ctgccgtttg acgcatccct ttatcctgca tcgctttttc
    15601 caagagctct ggcttggtat acaggttatg tggcattttg cggaattttt ctcgccaaaa
    15661 gtattgaccg ttcgggattt catccagatg actgaggtct tttcgcgcca aagtttccag
    15721 tgcatccgga ctgcctcccg cgtgaacgag gaccgcatca aagccagtcc cgatctggat
    15781 aaaataaggg cggatactgc ggacaggtcc gattacttct ggtgtttggc tttggaatat
    15841 cgcaagaaag cgggtcattt ccccttctga caatacctca taaatcatgt ccgctttgtt
    15901 gatgcctgtt tgtggacggg cgggcggagc attgttgatc atcaccatga tcggtcgttt
    15961 gctccccaga ttttcgtgac tgccaagtcc tgtcatcggt gccttatacg catattggat
    16021 gggctgattc gtttccggtg gcgtttgcac aatcggatca ggcatctgcg gactcggttg
    16081 ggtgtccacc ggcttttgac cgcaggccgt agttaagagc atgaaggcta gtaccatgag
    16141 agacgatttg actgttcgtt tcatatgaat cgctcctttc catctctcgt tgttgttttt
    16201 tcccctgttt ctttttccag aaggatacag gtgaatcctg cttccacacg ttttccacga
    16261 ttctcatacg tccgtgccac acatcttgtt tttggctatg ctacaatatt gatataaaac
    16321 agatgcaaag cgaggccgaa atccatgaat accccctacc tcgtctatct ggtggacgat
    16381 gaaacgaacc tgttggagct gctgcaatcc tatttgcaaa gtgccggatt gcaggtgaaa
    16441 gcgttttcta gtggcaagga cgtcttgccg ttacttgatg aagaaacaca accacatctg
    16501 tggatattgg acatcatgat gcccgacatc gacggctacg agctcttgcg ccttatccgc
    16561 gaaaagtcga atgtacccat catcttcatc tctgctcgcg atcaggatgt cgataaaatc
    16621 atcggactgg aactgggcag cgatgactac ttggcgaaac catttctacc acgtgaactg
    16681 gtcatccgtg cgaaaaagct gctacagcgt acctatgaga agtccaatgg cactgcttcc
    16741 tctacccaaa ctttccaaga ttgggtaacg gttgatcctt atatgatctc agaaaaaggc
    16801 agacaagtaa aagaaggcga cgaactcatt gatctaacta caaaagaatt cgagctaatc
    16861 gtctaccttt tgcacaatca aggtctggcc ttgaatcgcg agcagattct gacttccatc
    16921 tggggggaag actacatcgg ctcagacagg gctgtcgatg acttggtgaa gcgtatccgc
    16981 aagaaaatgc ccaagtttcc attggagacg gtctatggct tcggctaccg tatgacacgt
    17041 ctatgagcaa attccgactg aaaaacctgc cgatatccag gcaaatcctc attttgttca
    17101 tgatcctgac aagcgtcctc ggggttggcc ttggtatcgg gtatccaatg gctgtcaaac
    17161 agtacctggt ctccaacact tactcgctct tggaagaaga gttttacacc ttatctcagc
    17221 atatctcctt caacgagcat aatgagctgc tgcctgtccc ggctgcggcc ccttactttt
    17281 tacagctctt gctccaacgt tatgagtact catttgatat gatcgtctat gctgaaaacg
    17341 gtcaggagct gggtcgccgg agcaatacca atggccgcat tccgtatgag gataccaagg
    17401 agctgttcct aaaagcagcc acatacccaa gccaaaagct gcagcatggt tcgctggacc
    17461 gtggagccga gagctatttg ttcgtcagca aaaaaatgga ctaccacggc ttcccttact
    17521 acatggtgct gttctccaag gaacaggagc tcaaccagat caactcgatt ttgacacgtc
    17581 agtttttact cgtgtttggt ctgctgctgc tcgtaagctg gctgttggcc gtgtggttta
    17641 gcgggtattt gagcagaccg ctgcgcacac ttgaagagtt gtgcaaaaag atcgcccgtc
    17701 gtcagttcga tatcccgctt gcgatggatc gcggagatga gatcggacag ctcgcccgct
    17761 ctttcgatat gatgaaaaac caactgaagg aatacgacga gtcgcagcag cattttgtcc
    17821 aaaatatttc ccatgagctc aaaacaccga ttatggcgat tcaaggatat acgcaaggac
    17881 tcatcgaagg cgtcttccag ggacctcagg ctgaaaaagg actttctatc atcatggaag
    17941 agagcaagcg cctcgaaaag gtcgtcggac agctcttgta catcacgaag atcgagtctg
    18001 tctcccaaat gatgcaagtc gaccgcgtcg acctgtcaga gatgatgcac ctgttgaaac
    18061 agcggctctc cgtgctcaat ccgcaaatcg agtgggagtt aaatctggca gctgacttga
    18121 tcgtagaggg agacggcgag caattgagca ctgcgttcgt caatatcatg gaaaatcaac
    18181 tgcgctacgc caaaagccga ctgactatca caggaagaca cgcgggaaaa agcgtcgtcg
    18241 tcgcgatttc caatgatggg ccacccattg aggaggcgct gctgccgaat ttgttccagc
    18301 gtttccgcaa aggaaagtcg ggcaagcatg ggcttggact tgcgattgcc cgtgccgtct
    18361 tggaagcaca taaagggacg atcgatgccc gcaacgatcc agatggacct tgctttacga
    18421 tgattgtacc tgttgaattt aaaggccgat taaattgata ggaggggaca cttgtcctct
    18481 ctttttctat tctaaaggac aaattcaata aaagcgtaag aagataccgt gacaaaaccg
    18541 agcttctcat atacgtgcat cgcagtcgga ttatccgcaa agaccatcaa ataaacattc
    18601 gcagacttct ccaagccgat ccgggaaata tctgagctga tttgcgtacc caaccctttt
    18661 tgccaatgat gaacagatgt tccaatgttc ccgatttcta cgtaggcttc gtcatagaca
    18721 tgaaagcctg ctacggccat tggctcgcca tcttccgaaa agagcgcgat gtgcggcatt
    18781 tcggctactt cctccgcccg gaaactaatc atgccgagct ctgccgccat atcctccacg
    18841 atctgtgctt cggataactc cagtattcgt gattcgccca caggtaaaag acgctctgga
    18901 tctgtaagtt tcatcagacg catggtacgt gtggcgagta tattcggaat ctgtacgcgc
    18961 gtcaggagag gctctgctag tgcaatcacg cccttttgtc catctgacag gctgccgtct
    19021 agcacttctt tcatatagga gagtatcggc tccacctcgt aatttttctc cccctctact
    19081 acatgaagag aaaacgcatg aaacggcatc cctttcaagt aagacccgat gacggttact
    19141 tctccctgaa cgctgtccgt tacgacgacg ctcctgtccg ttcgcacgta catattcccg
    19201 tacaaaatgt acgaatcttc taacgaaatt tgccccaaaa gctggcgttg ttcatgacct
    19261 gttcgcaatt ttagcaaaga aatctctcct tctatcgatt ccctattgac gttgtcgtgc
    19321 ttcgcggtta acatggtaaa aatttctctg tttaaagagg cagttcaaaa aatggagacc
    19381 aacttcacct aggaggagag aatcgtggct ttttattaca cagaaccatc tcggacgttt
    19441 aatgagtttt tgctgttgcc aaatctcacc acaaaagaat gcactccgaa caatgtggac
    19501 ttatccactc cgattaccaa gtataaaaaa ggtgaaaagc ctgccatcac actaaacata
    19561 ccgttctcat ccgcagtcat gcaagcagtt tccgaccatc atatggcggt cgcattggct
    19621 agatgtggcg gtatttcgtt tatttttggc tcccagtcca tcgagagcca ggcaaccatg
    19681 gttcgcaaag caaaaggcta caaggctggt ttcgtcgtta gccgctccaa cctgacacca
    19741 agccatacgc tgaaagacat tttggaattg aaagaggcga caggccactc caccgttgcc
    19801 attacggaag atggtacggc aaaaggcaag ttgctcggaa tcgtaaccgg acgcgattat
    19861 cgcatcagcc gcgactcttt ggacaaactc gtcagcgaca tcatgacacc attctcgaag
    19921 ctgatctatg gcaaatccgg catcacgctc tccgaagcca acgacctgat ctgggagcac
    19981 aagctcaact gcttgccaat cgtagatgaa aatcaaaatc tcgacttcct cgttttccgc
    20041 aaagactacg attcccgcaa aaacaatccg ctgtccctct tggacgcgaa caaaagctat
    20101 atcgtaggtg ctggtatcaa tacaaaggac tacaaggagc gcgtccctgc gttggtggaa
    20161 gcaggcgttg atattctggt catcgactcc tccgacggct tcagcgaatg gcagcgcgag
    20221 acggttcaat atgtaaaaga aaacttcaat gttccgatcg gtgcaggtaa tgtcgtcgat
    20281 aaggaaggct tccgctacct cgtggaatcg ggcgcagatt tcataaaagt agggattggc
    20341 ggcggctcca tctgcattac ccgcgagcaa aaaggaatcg gacgcggtca agcctcttcc
    20401 ctcattgaag tggcagcagc tcgcgacgag tacttcaagg aaacaggcat ttacgttccg
    20461 ctctgctctg acggcggaat cgtacacgac taccacgtga cactggcttt agctatgggt
    20521 gcagactttg tcatgctggg ccgttacttc gctcgcttcg acgaaagccc gaccaaaaaa
    20581 gtgaagatcg gcaacaactt cgtgaaagaa tactggggag aaggctccaa ccgcgctcgc
    20641 aactggcaac gctatgacac tggcggaaaa agcagtctcg tctttgaaga aggcgtagac
    20701 tcctacgtcc catacgcggg aagcctgcgc gagaacatgg accgtacctt gagcaaaatc
    20761 aaatcgacca tgtgcaattg cggttcgctc tccatctcag agcttcaaca aaaagcgcgg
    20821 atcaccgtca tctctgctac cagcttggta gaaggcggcg cacatgacgt tatcttgaaa
    20881 gaaagcagca tggctgctga gtaagacaat gaattcgtag tcacaaaaaa acagtctgcc
    20941 gcacttctag cagactgttt tttttcttct tagggccccc acactcaata agagaatggg
    21001 caaaaacaaa ccgtacgtta gggaataagg catccaaatt tccgaaacaa aagtatcaaa
    21061 ataagggcgg ttaggcatcg tcgccaatgc caccacgatc atgatcatcc ccagcggaag
    21121 tgtcaattgg cgataatccc gcaaccccag cgtat
//
