LOCUS       c00022_NZ_JALC..       20321 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_JALCKS010000022.1 MAG: Aneurinibacillus aneurinilyticus isolate
            UW_TS_ANEURI1_1 Ga0455822_00106, whole genome shotgun sequence.
ACCESSION   c00022_NZ_JALC..
VERSION     c00022_NZ_JALC..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 16:17:21
            Original ID  :: NZ_JALCKS010000022.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 53953
            Orig. end    :: 74274
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..20321
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[63953:64274](+)"
                     /cutoff="20000"
                     /detection_rule="(PoyD or TIGR03793)"
                     /neighbourhood="10000"
                     /product="proteusin"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10321
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PoyD or TIGR03793)"
                     /neighbourhood="10000"
                     /product="proteusin"
                     /protocluster_number="1"
     cand_cluster    1..20321
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PoyD or TIGR03793)"
                     /kind="single"
                     /product="proteusin"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..20321
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="proteusin"
                     /region_number="2"
                     /rules="(PoyD or TIGR03793)"
                     /tool="antismash"
     CDS             complement(300..737)
                     /locus_tag="ctg22_38"
                     /transl_table=11
                     /translation="VNTQTIQTNGQAFPFTWMEDFEEYSTMLNNEAERSELLSRLLYEK
                     YPFIKRLNYESGQPVLELISNQELKKIRGIRFGHRTRAKKLVFFYKGQEQQAWFPQVEI
                     NGVFVFIRHDEYPVQVVECTSRYLALKYARRFMARKHKSIV"
     CDS             complement(960..1595)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_39"
                     /sec_met_domain="PCMT (E-value: 6.7e-07, bitscore: 21.3,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNQEEYIRSLFAQPDEILADVIKSIERQGMPSISVSPEGGIFLTM
                     LVRTANAKQILEIGALGGYSGICLLRGLRGEGHLTSLELKQEYADLAHANLKKAGVGEQ
                     VTYRIGEALDSLGQLEREGKTFDFFFIDADKPNYSNYLGHCIRLANPGAIIVADNVLWH
                     GRVYDETAQEDSTRALRAFNEKIAGDSRLESLLIPLGDGMAMARVKEK"
     PFAM_domain     complement(975..1559)
                     /aSDomain="Methyltransf_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01596.19"
                     /description="O-methyltransferase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg22_39_0051"
                     /evalue="1.50E-51"
                     /label="ctg22_39"
                     /locus_tag="ctg22_39"
                     /protein_end="207"
                     /protein_start="12"
                     /score="174.7"
                     /tool="antismash"
                     /translation="QPDEILADVIKSIERQGMPSISVSPEGGIFLTMLVRTANAKQILE
                     IGALGGYSGICLLRGLRGEGHLTSLELKQEYADLAHANLKKAGVGEQVTYRIGEALDSL
                     GQLEREGKTFDFFFIDADKPNYSNYLGHCIRLANPGAIIVADNVLWHGRVYDETAQEDS
                     TRALRAFNEKIAGDSRLESLLIPLGDGMAMAR"
     CDS             1887..2063
                     /locus_tag="ctg22_40"
                     /transl_table=11
                     /translation="MDIAAMATSLKAASLGTAVSLAVTKKAMDTQKEAGAQLVELLEKS
                     VQPHLGNRIDIRA"
     PFAM_domain     1893..2054
                     /aSDomain="YjfB_motility"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14070.8"
                     /description="Putative motility protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg22_40_0052"
                     /evalue="3.60E-21"
                     /label="ctg22_40"
                     /locus_tag="ctg22_40"
                     /protein_end="56"
                     /protein_start="2"
                     /score="75.2"
                     /tool="antismash"
                     /translation="IAAMATSLKAASLGTAVSLAVTKKAMDTQKEAGAQLVELLEKSVQ
                     PHLGNRIDI"
     CDS             complement(2146..3210)
                     /locus_tag="ctg22_41"
                     /transl_table=11
                     /translation="VEKTILLCDMNSFFASVHQSYNPQLRNKPVIVAGNPEKRKGIVVA
                     ASYDAKAKGVYTTMRFYRARKLCPEAVFVQPNHALYRRYSEAIMRFLRRIAPCEVASVD
                     EAYLDISELVAKGHTARIIAEYIQDKLYRELLIPSSIGAGPTKLIAKMCADVKKPGGFV
                     EMGARQYRTYFWPQTVGSLHGCGKSTAERLQRKGIRTIGELAAQPVEDLRSWFGKKGEY
                     LHQAANGTYESPVNPERQKGEKSIGSSRTFAFDTMDQALIAKTAREFSEKLADKLKQKQ
                     KKAKTIVVEVKFDYRQAVSRSLALAGATDEAEEIYRAAMQLYEVYFSSQPLRLFGIRLH
                     HLLDEEYEQLRFSF"
     PFAM_domain     complement(2161..2481)
                     /aSDomain="IMS_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF11799.10"
                     /description="impB/mucB/samB family C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg22_41_0054"
                     /evalue="4.30E-18"
                     /label="ctg22_41"
                     /locus_tag="ctg22_41"
                     /protein_end="350"
                     /protein_start="243"
                     /score="65.9"
                     /tool="antismash"
                     /translation="KSIGSSRTFAFDTMDQALIAKTAREFSEKLADKLKQKQKKAKTIV
                     VEVKFDYRQAVSRSLALAGATDEAEEIYRAAMQLYEVYFSSQPLRLFGIRLHHLLDEEY
                     EQL"
     PFAM_domain     complement(2749..3189)
                     /aSDomain="IMS"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00817.22"
                     /description="impB/mucB/samB family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg22_41_0053"
                     /evalue="3.20E-43"
                     /label="ctg22_41"
                     /locus_tag="ctg22_41"
                     /protein_end="154"
                     /protein_start="7"
                     /score="147.4"
                     /tool="antismash"
                     /translation="CDMNSFFASVHQSYNPQLRNKPVIVAGNPEKRKGIVVAASYDAKA
                     KGVYTTMRFYRARKLCPEAVFVQPNHALYRRYSEAIMRFLRRIAPCEVASVDEAYLDIS
                     ELVAKGHTARIIAEYIQDKLYRELLIPSSIGAGPTKLIAKMCA"
     CDS             3372..4130
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_42"
                     /sec_met_domain="Abhydrolase_6 (E-value: 2.1e-14, bitscore:
                     46.7, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 2.1e-11, bitscore: 36.0,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEKYPVLQNAEPFYMQGGDIGVLVQHGFTGTTQSMRFLGESLAQ
                     VGFTVYAPRLKGHGTHYEDMEATSYEDWITSAEEGYQKLKASCREVFVVGLSMGGTIAL
                     HLAEEHPEIAGIMLINAAIRVENFEPLANETARYLDAIGSDIKAPDVAELAYSKTPVAS
                     VKQFLTFKNIVASRLSAITCPALVLVSREDHVVPPEDSDYILAHIMSELKEKVVLENSY
                     HVATLDNDKELIARQCAAFISEINQMKTKS"
     PFAM_domain     3438..4055
                     /aSDomain="Hydrolase_4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12146.10"
                     /description="Serine aminopeptidase, S33"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg22_42_0055"
                     /evalue="2.50E-22"
                     /label="ctg22_42"
                     /locus_tag="ctg22_42"
                     /protein_end="228"
                     /protein_start="22"
                     /score="79.4"
                     /tool="antismash"
                     /translation="VLVQHGFTGTTQSMRFLGESLAQVGFTVYAPRLKGHGTHYEDMEA
                     TSYEDWITSAEEGYQKLKASCREVFVVGLSMGGTIALHLAEEHPEIAGIMLINAAIRVE
                     NFEPLANETARYLDAIGSDIKAPDVAELAYSKTPVASVKQFLTFKNIVASRLSAITCPA
                     LVLVSREDHVVPPEDSDYILAHIMSELKEKVVLENSYHVATLD"
     CDS             4471..4911
                     /locus_tag="ctg22_43"
                     /transl_table=11
                     /translation="MRKPILLLLAACTITVPFLTSYPASAMPHQTEQHNNSVQPQSTID
                     SQAEITKGGRGGRGGVGITPRRPADGGYRSRYEAPVTRPTPSSGIGRGLWAFGLGALFG
                     SILHPFSGAYGFGFSFIGLLFWALVLFMVYKYFRRFFSRTKT"
     PFAM_domain     5190..5381
                     /aSDomain="CSD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00313.24"
                     /description="'Cold-shock' DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg22_44_0056"
                     /evalue="7.60E-33"
                     /label="ctg22_44"
                     /locus_tag="ctg22_44"
                     /protein_end="64"
                     /protein_start="0"
                     /score="112.3"
                     /tool="antismash"
                     /translation="MNGTVKWFNAEKGFGFIEREDGDDVFVHFSAITGDGFKSLEEGQQ
                     VQFDIVEGNRGPQAANVVK"
     CDS             5190..5387
                     /gene_functions="regulatory (smcogs) SMCOG1255:cold-shock
                     DNA-binding domain protein (Score: 94.8; E-value: 4.3e-29)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg22_44"
                     /transl_table=11
                     /translation="MNGTVKWFNAEKGFGFIEREDGDDVFVHFSAITGDGFKSLEEGQQ
                     VQFDIVEGNRGPQAANVVKL"
     CDS             complement(5492..5659)
                     /locus_tag="ctg22_45"
                     /transl_table=11
                     /translation="MEIYLWTAMFYIVVFIGIISIVGMVVNRSAQGTHERIDQLQQQVR
                     KLEEELKKKS"
     CDS             complement(5737..7158)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1105:amidase (Score: 459.3; E-value: 2.5e-139)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_46"
                     /transl_table=11
                     /translation="VINSDILQLDIYNLSCKIRNKEISPVEIVKQLLKRIEEINPSIQA
                     FITVASEEAIASAKKAETEIGRGEWKGYLHGVPIGLKDLIYTKGIRTTMGSKIYHHFVP
                     DFDATVVQKLKNAGAILIGKLNTHEFAYGPTGDVSFFGPARNPYNTNHMSGGSSSGSGV
                     AVASALCFGALGTDTGGSIRIPSSACGIVGMKPTFGRVSKHGVYPLGYTLDHVGPMTRT
                     IKDNALLLNVLAGYDPQDPYSRKSENEDFSRYIGDSVKGRVIGVPSSFYFDCLEDEVKE
                     RMKEAVAMFQEMGAQCKPVDIPILSRTSWAQLKTLQSEAYDVHEEHLKQESGNFHPEVL
                     ERLRLSAEAKGHEYVQAQTIRRQALESFEKIFEHVDVLVTPTLPILPPKIGQREIKIQG
                     QTEQVRAALLRLTGPTNLTGLPSLSVPCGFSATGLPIGMQLISRPLNEAILYQFGAAFE
                     DEAGIPSLKWKIETA"
     PFAM_domain     complement(5815..7080)
                     /aSDomain="Amidase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01425.23"
                     /description="Amidase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg22_46_0057"
                     /evalue="6.20E-124"
                     /label="ctg22_46"
                     /locus_tag="ctg22_46"
                     /protein_end="448"
                     /protein_start="26"
                     /score="414.5"
                     /tool="antismash"
                     /translation="EIVKQLLKRIEEINPSIQAFITVASEEAIASAKKAETEIGRGEWK
                     GYLHGVPIGLKDLIYTKGIRTTMGSKIYHHFVPDFDATVVQKLKNAGAILIGKLNTHEF
                     AYGPTGDVSFFGPARNPYNTNHMSGGSSSGSGVAVASALCFGALGTDTGGSIRIPSSAC
                     GIVGMKPTFGRVSKHGVYPLGYTLDHVGPMTRTIKDNALLLNVLAGYDPQDPYSRKSEN
                     EDFSRYIGDSVKGRVIGVPSSFYFDCLEDEVKERMKEAVAMFQEMGAQCKPVDIPILSR
                     TSWAQLKTLQSEAYDVHEEHLKQESGNFHPEVLERLRLSAEAKGHEYVQAQTIRRQALE
                     SFEKIFEHVDVLVTPTLPILPPKIGQREIKIQGQTEQVRAALLRLTGPTNLTGLPSLSV
                     PCGFSATGLPIGMQLISRPLNEA"
     CDS             complement(7218..7745)
                     /locus_tag="ctg22_47"
                     /transl_table=11
                     /translation="MNNTLWESSYFPLFDSISLGIILLDHDERILHMNRFASQQLRFTS
                     EEGTPLSLGDVFSFLSINQSGWIEDNFHFVYDVIYVSDADGITLRVSSACEALWGYREE
                     DLVGKSTYELEKEGVFYPSITRLVLERQEQVSMIQTTKTGRRLKVVGTPIKDKENRELE
                     RSNPISEKSIIQ"
     PFAM_domain     complement(7275..7514)
                     /aSDomain="PAS"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00989.27"
                     /description="PAS fold"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg22_47_0059"
                     /evalue="9.90E-06"
                     /label="ctg22_47"
                     /locus_tag="ctg22_47"
                     /protein_end="157"
                     /protein_start="77"
                     /score="25.6"
                     /tool="antismash"
                     /translation="VIYVSDADGITLRVSSACEALWGYREEDLVGKSTYELEKEGVFYP
                     SITRLVLERQEQVSMIQTTKTGRRLKVVGTPIKDK"
     aSDomain        complement(7311..7517)
                     /aSDomain="TIGR00229"
                     /aSTool="tigrfam"
                     /description="sensory_box: PAS domain S-box protein"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg22_47_0009"
                     /evalue="2.60E-06"
                     /identifier="TIGR00229"
                     /label="ctg22_47"
                     /locus_tag="ctg22_47"
                     /protein_end="145"
                     /protein_start="76"
                     /score="25.5"
                     /tool="antismash"
                     /translation="DVIYVSDADGITLRVSSACEALWGYREEDLVGKSTYELEKEGVFY
                     PSITRLVLERQEQVSMIQTTKTGR"
     PFAM_domain     complement(7575..7709)
                     /aSDomain="PAS_8"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13188.9"
                     /description="PAS domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg22_47_0058"
                     /evalue="2.40E-04"
                     /label="ctg22_47"
                     /locus_tag="ctg22_47"
                     /protein_end="57"
                     /protein_start="12"
                     /score="21.2"
                     /tool="antismash"
                     /translation="LFDSISLGIILLDHDERILHMNRFASQQLRFTSEEGTPLSLGDVF
                     "
     CDS             complement(8233..8487)
                     /locus_tag="ctg22_48"
                     /transl_table=11
                     /translation="LVTSREYRLGVLRGIYVRHLRSRSKTMSILVKTRTELLAYTYLAK
                     RGFISMEQEDATSSRFNVSLLHAGIDYIESMEVKQGITV"
     CDS             9012..9785
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 134; E-value:
                     1.2e-40)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg22_49"
                     /transl_table=11
                     /translation="MFLSFSHFSTSSIDIHSKNPNFSRTLQMILRVAQYPSTALIEGET
                     GTGKEKIATLIHEASPRSMMPFVKINCGAIPDALAESELFGYEGGAFMGAKKEGQFRED
                     LYYRLQVAHFIIPALRERPEDLPYLIDLFLYRFSEIYKMPIKIFSEEVMERFLHYHWPG
                     NIRQLQNCIEGIYATIEHETVCLEELPAFLQNSSNIHIKPTGLREQVAAFEKQIIERVL
                     QETKSLRQAATILHIPHATLLRRIEKWGIQKNKDT"
     PFAM_domain     9060..9308
                     /aSDomain="Sigma54_activat"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00158.28"
                     /description="Sigma-54 interaction domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg22_49_0060"
                     /evalue="1.90E-26"
                     /label="ctg22_49"
                     /locus_tag="ctg22_49"
                     /protein_end="99"
                     /protein_start="16"
                     /score="92.9"
                     /tool="antismash"
                     /translation="SKNPNFSRTLQMILRVAQYPSTALIEGETGTGKEKIATLIHEASP
                     RSMMPFVKINCGAIPDALAESELFGYEGGAFMGAKKEG"
     PFAM_domain     9624..9767
                     /aSDomain="HTH_50"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF18024.3"
                     /description="Helix-turn-helix domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg22_49_0061"
                     /evalue="4.50E-09"
                     /label="ctg22_49"
                     /locus_tag="ctg22_49"
                     /protein_end="252"
                     /protein_start="204"
                     /score="35.9"
                     /tool="antismash"
                     /translation="GLREQVAAFEKQIIERVLQETKSLRQAATILHIPHATLLRRIEKW
                     GIQ"
     CDS             9790..9927
                     /locus_tag="ctg22_50"
                     /transl_table=11
                     /translation="MVRKRAVLLSYLHAKLAPTTPEFLLSEKINADCSLHLFKNCMIVI
                     "
     CDS             10001..10321
                     /gene_functions="biosynthetic (rule-based-clusters)
                     proteusin: TIGR03793"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_51"
                     /sec_met_domain="TIGR03793 (E-value: 2.6e-17, bitscore:
                     54.5, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDWNMEKLNEAVKQFQEKATIDAKFRKLALENPSRAVKQLTGLEI
                     PEGFKLHVVDNAGAHLTVVLPDLKATEHELDEAELQNVAGGTSFSSFILYSSKDQYYSS
                     RK"
     aSDomain        10028..10258
                     /aSDomain="TIGR03793"
                     /aSTool="tigrfam"
                     /description="TOMM_pelo: NHLP leader peptide domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg22_51_0010"
                     /evalue="7.10E-16"
                     /identifier="TIGR03793"
                     /label="ctg22_51"
                     /locus_tag="ctg22_51"
                     /protein_end="86"
                     /protein_start="9"
                     /score="55.8"
                     /tool="antismash"
                     /translation="EAVKQFQEKATIDAKFRKLALENPSRAVKQLTGLEIPEGFKLHVV
                     DNAGAHLTVVLPDLKATEHELDEAELQNVAGG"
     CDS             10792..11058
                     /locus_tag="ctg22_52"
                     /transl_table=11
                     /translation="MSNRKSFFRLFAKNLKESLGPGRYEVYGIVVTCPHCKHDRFQHGY
                     AQLNTAFMTLLNLDFANRSAETLTCEQCGNIQWFNKTVRPYKY"
     CDS             11566..12141
                     /locus_tag="ctg22_53"
                     /transl_table=11
                     /translation="MNNIYTKMVDMMSIDETTYHDICMISHGSHMPYHGIYTISRDSHM
                     PYHGIYMTSRDSHMPYHGIYMTSRDSHMPYHDIYMTSRDSHMPYHGIYMTSRDSHMPYH
                     GIYTISRDGHMPYHGIYTISHGNHMPYHDIYMISRDSHMLYHDIYMIHHDNDYFCLYNS
                     CLNSCYREACVHENCSYPYNRTEKHKTF"
     CDS             complement(12237..12461)
                     /locus_tag="ctg22_54"
                     /transl_table=11
                     /translation="MYGTPLRIILIDKQPYHLRKVFLCVWTFGLLPNPTLRSFGLPLTP
                     DGRIIVDASYRVKGAAGVYSIGDCAHITF"
     PFAM_domain     complement(12252..12404)
                     /aSDomain="Pyr_redox_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07992.16"
                     /description="Pyridine nucleotide-disulphide
                     oxidoreductase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg22_54_0062"
                     /evalue="4.00E-09"
                     /label="ctg22_54"
                     /locus_tag="ctg22_54"
                     /protein_end="70"
                     /protein_start="19"
                     /score="36.2"
                     /tool="antismash"
                     /translation="KVFLCVWTFGLLPNPTLRSFGLPLTPDGRIIVDASYRVKGAAGVY
                     SIGDCA"
     CDS             complement(12907..13476)
                     /locus_tag="ctg22_55"
                     /transl_table=11
                     /translation="MKKQMLISCLVLSCGFLSVNPVIAEPVTAAVKKQAASPTQIKKID
                     EKNIISLLVEAENRYFYTLGGGKGKTEVFNIKDSQYRYLSSDIGTRKKLLDYLMKAFTK
                     EASETYIKERFIEYKGRMAQVNADKGNILEFNKATAKLIKGSSTMKEYQLSIPYPEHQS
                     KPEIKTIKVKKVNGVWRIATSPEKLF"
     PFAM_domain     complement(12928..13356)
                     /aSDomain="Endopep_inhib"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF16800.7"
                     /description="IseA DL-endopeptidase inhibitor"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg22_55_0063"
                     /evalue="5.60E-29"
                     /label="ctg22_55"
                     /locus_tag="ctg22_55"
                     /protein_end="183"
                     /protein_start="40"
                     /score="101.1"
                     /tool="antismash"
                     /translation="IKKIDEKNIISLLVEAENRYFYTLGGGKGKTEVFNIKDSQYRYLS
                     SDIGTRKKLLDYLMKAFTKEASETYIKERFIEYKGRMAQVNADKGNILEFNKATAKLIK
                     GSSTMKEYQLSIPYPEHQSKPEIKTIKVKKVNGVWRIAT"
     CDS             14487..15149
                     /gene_functions="regulatory (smcogs) SMCOG1057:TetR family
                     transcriptional regulator (Score: 98; E-value: 1.5e-29)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg22_56"
                     /transl_table=11
                     /translation="MRVIKKAEERRNEILDAADELFGQKGFDGTSTNDILEKVGIARGT
                     LYYHFKSKENIMDALIERYTVLLLGAAKEIAADKSIPINERIIRVVMALNINDGNGKEI
                     IEHIHKPQNALMHQKIQKVIINSVPPILTEIIREGIEQGLFSTPYPYECMEMAVAYTNT
                     IFDDDMVNMTNEERASRIQAFVFNIERLLGVESGSLMYMMKMFDSGNTGRRNKNSNE"
     PFAM_domain     14526..14666
                     /aSDomain="TetR_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00440.25"
                     /description="Bacterial regulatory proteins, tetR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg22_56_0064"
                     /evalue="1.40E-18"
                     /label="ctg22_56"
                     /locus_tag="ctg22_56"
                     /protein_end="60"
                     /protein_start="13"
                     /score="66.5"
                     /tool="antismash"
                     /translation="ILDAADELFGQKGFDGTSTNDILEKVGIARGTLYYHFKSKENIMD
                     AL"
     CDS             complement(15317..16009)
                     /locus_tag="ctg22_57"
                     /transl_table=11
                     /translation="MNVLETLGRTTLAFFILLVMTRVLGKKQVSELTFFNYVTGITFGS
                     IAAVMAMDRSIPIVEGIVSLMIWTVLTFLIGYIGLKSPRARVLLDGEPTIVVKKGKVLE
                     GAMRDAHYNMDDLSMMLREKGVFSVQEIEYAILEPDGQLSILKKPEHQTPTNKGINIAA
                     QPLIYVPTELIVDGEVVHKNLKDLNLSVAWLDEQVQKAGVSSHEEVFYAELQSDGTVYM
                     DKRNDLLH"
     PFAM_domain     complement(15398..15748)
                     /aSDomain="DUF421"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04239.14"
                     /description="Protein of unknown function (DUF421)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg22_57_0065"
                     /evalue="2.80E-33"
                     /label="ctg22_57"
                     /locus_tag="ctg22_57"
                     /protein_end="204"
                     /protein_start="87"
                     /score="114.0"
                     /tool="antismash"
                     /translation="LLDGEPTIVVKKGKVLEGAMRDAHYNMDDLSMMLREKGVFSVQEI
                     EYAILEPDGQLSILKKPEHQTPTNKGINIAAQPLIYVPTELIVDGEVVHKNLKDLNLSV
                     AWLDEQVQKAGVS"
     CDS             16960..18060
                     /locus_tag="ctg22_58"
                     /transl_table=11
                     /translation="MNKPRRNGITLLQYILGVNVTQIGTSILTLPSELAKMATTDGWIS
                     IVVGWMIATIVSLCIIGVMAKHPGATIYDVLTHYLGKWFGGAWIIILMCSSLFIAMIVF
                     YEVLRLIKLFILPNTSSGLLAIFFMIPTYMVLRSGIRIFARYAEFVFFFTLWLPILLLV
                     PLKDAEFIFMLPVLKEGMLPILHAVAPAVISFIGFEIAFILYPYLKNKQAAARGIVIAN
                     TITLLVYLQITLSCFLYFSPDEITNLLWPTLTLVKPIHFPFFERFEILFLSFYMFIFST
                     SFLPSIFIVTENINQFFGKQNWQLPICILLSLILAASFVYIPTHSQLEVMSKWWNWDAY
                     IVFCVFPVLFFLYATLYTRWKQRKTV"
     PFAM_domain     16984..17913
                     /aSDomain="Spore_permease"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03845.15"
                     /description="Spore germination protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg22_58_0066"
                     /evalue="4.90E-55"
                     /label="ctg22_58"
                     /locus_tag="ctg22_58"
                     /protein_end="318"
                     /protein_start="8"
                     /score="186.7"
                     /tool="antismash"
                     /translation="ITLLQYILGVNVTQIGTSILTLPSELAKMATTDGWISIVVGWMIA
                     TIVSLCIIGVMAKHPGATIYDVLTHYLGKWFGGAWIIILMCSSLFIAMIVFYEVLRLIK
                     LFILPNTSSGLLAIFFMIPTYMVLRSGIRIFARYAEFVFFFTLWLPILLLVPLKDAEFI
                     FMLPVLKEGMLPILHAVAPAVISFIGFEIAFILYPYLKNKQAAARGIVIANTITLLVYL
                     QITLSCFLYFSPDEITNLLWPTLTLVKPIHFPFFERFEILFLSFYMFIFSTSFLPSIFI
                     VTENINQFFGKQNWQLPICILLSLILAAS"
     aSDomain        16984..18042
                     /aSDomain="TIGR00912"
                     /aSTool="tigrfam"
                     /description="2A0309: spore germination protein (amino acid
                     permease)"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg22_58_0011"
                     /evalue="2.20E-69"
                     /identifier="TIGR00912"
                     /label="ctg22_58"
                     /locus_tag="ctg22_58"
                     /protein_end="361"
                     /protein_start="8"
                     /score="232.5"
                     /tool="antismash"
                     /translation="ITLLQYILGVNVTQIGTSILTLPSELAKMATTDGWISIVVGWMIA
                     TIVSLCIIGVMAKHPGATIYDVLTHYLGKWFGGAWIIILMCSSLFIAMIVFYEVLRLIK
                     LFILPNTSSGLLAIFFMIPTYMVLRSGIRIFARYAEFVFFFTLWLPILLLVPLKDAEFI
                     FMLPVLKEGMLPILHAVAPAVISFIGFEIAFILYPYLKNKQAAARGIVIANTITLLVYL
                     QITLSCFLYFSPDEITNLLWPTLTLVKPIHFPFFERFEILFLSFYMFIFSTSFLPSIFI
                     VTENINQFFGKQNWQLPICILLSLILAASFVYIPTHSQLEVMSKWWNWDAYIVFCVFPV
                     LFFLYATLYTRWK"
     CDS             complement(18517..18975)
                     /locus_tag="ctg22_59"
                     /transl_table=11
                     /translation="VWEKFSSYITRIISPLDATATSMYASNTGGSTILVVAGGINVALP
                     NNQNLESFTVNSGNAIFTVPANGRYYLAYQINTTTALLVGARLTRNGTPIPGSILSPAV
                     ATSSYNNNVIISLNVGDTIALQLFGLVATAVLVGGGSAGAALTIIRLS"
     PFAM_domain     complement(18520..18909)
                     /aSDomain="BclA_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF18573.3"
                     /description="BclA C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg22_59_0067"
                     /evalue="2.10E-46"
                     /label="ctg22_59"
                     /locus_tag="ctg22_59"
                     /protein_end="152"
                     /protein_start="22"
                     /score="157.1"
                     /tool="antismash"
                     /translation="MYASNTGGSTILVVAGGINVALPNNQNLESFTVNSGNAIFTVPAN
                     GRYYLAYQINTTTALLVGARLTRNGTPIPGSILSPAVATSSYNNNVIISLNVGDTIALQ
                     LFGLVATAVLVGGGSAGAALTIIRLS"
ORIGIN
        1 gaaagggctt accttctata tttatctgct tcatccggca ttcattgtgt atgggaaccg
       61 gattatgaat gataatttcg ccattgattg gattttccat aacaaactag cctcggcatt
      121 atatctgcta gcgatttatg gagctacgtt tgcggcctct ttactgtgtg cccttattgt
      181 gaatcggggc ttcggttggc tgtcaaacga tcaaaaacga aagcaagcgt caaacaatgc
      241 ttaagagata taaaaataag gaaaaaaacc cttctgcgat attgcagaag ggcttttcgt
      301 tatactatgc tcttatgttt gcgagccatg aatcgccgcg cgtatttcag tgccagatac
      361 cgactcgtgc attccaccac ttgaaccgga tattcatcat ggcgaataaa gacgaataca
      421 ccattaattt ccacctgcgg aaaccatgcc tgctgctctt gtcctttgta aaaaaacacc
      481 agtttcttcg ccctggtacg gtgcccaaat ctaatgcccc taattttttt tagctcctga
      541 ttggagataa gctcaagtac aggctggcct gattcatagt tcagtcgctt aataaacgga
      601 tatttttcat acaacaggcg ggaaagcaat tccgagcgct ctgcttcatt attcaacatc
      661 gttgaatatt cttcgaaatc ttccatccag gtgaatggaa atgcctgtcc attcgtttgt
      721 attgtttgag tattcacgtc caaccatcct cttttatgta atttcgttag tttatactac
      781 attattacca ccgtaaaaag agaatgaaac attttttaac tttttagcta agaagttccc
      841 catttctaaa cgtgaaggcg cgacagcacc agtgagttat gatacgtagt atttttatac
      901 tttaaaagaa taaacaataa aacaagactg ccgaagtttt ttcgacagtc tggaagcttc
      961 tatttttctt tgacccttgc catagccata ccgtctccaa gtgggatgag tagcgattcc
     1021 agtcggctat ccccagctat tttttcattg aaagcacgaa gcgctcgcgt agagtcttct
     1081 tgagctgttt catcatagac acgaccatgc cacagcacat tgtccgcaac aataatagct
     1141 ccgggatttg caagacgaat acaatgcccc agatagttgg aatagttcgg cttgtcggca
     1201 tcaataaaaa agaaatcgaa tgtcttccct tctctctcca attgccctaa actatccagc
     1261 gcctcaccga ttcggtatgt tacttgctcc cccactccag ctttcttcaa atttgcatgg
     1321 gcaagatcgg catattcctg cttcagttcg agagaggtta gatgtccttc ccctcttagt
     1381 ccccgcagca ggcaaatgcc actgtatcca ccaagtgcac cgatttcgag gatttgcttc
     1441 gcatttgcag ttcgtacaag catcgtcaga aatataccgc cctccggcga gacagagata
     1501 gatggcatcc cttgccgctc aatgcttttg ataacatctg caagtatttc atctggttga
     1561 gcaaataacg aacggatgta ttcttcctgg ttcatcttac tgtatcgact ccttttccta
     1621 tccctgtatt ttataaaaaa taataacatg ctgattatgc tgattatctg attcgctttc
     1681 gttcattcat tccctgctga attctataaa attcataaca agaaaaaatg tgccgatata
     1741 taaagtggaa cctccatcag tgttggtctc ttcatctccc gctgatggtt cgttgcacag
     1801 ttcccaacca ccacaagaga tgtcattcag caagtcagac gtatatggtt gaaacaaaaa
     1861 ctgcaaacaa aagggaggag acacgaatgg atatcgccgc tatggccaca tcattaaagg
     1921 ccgcttcgct cggtactgct gttagcctgg ccgttactaa aaaggcaatg gatacacaaa
     1981 aagaagcggg cgcacagctg gtagaactat tggagaaaag cgtgcaaccg catctgggga
     2041 accgtatcga catacgggca tagtcgtctg catatgaata cgtacataca gaaagccgtc
     2101 ctcaatgggc ggctttcctg cttgcggaat atacgcacct cccctttaaa aagaaaaacg
     2161 gagctgctca tattcctcat ctagcagatg atggagtcga atgccaaaca gccgaagcgg
     2221 ctgtgacgaa aaatatactt cgtacaattg catggccgcc cgataaattt cctccgcctc
     2281 atctgttgca cccgccagtg ccaagctacg tgatacagcc tggcgataat cgaacttcac
     2341 ttctacgaca atcgttttcg cctttttctg tttctgcttc aacttatctg ctagcttctc
     2401 gctaaattcg cgagccgtct tagcaataag tgcctgatcc atcgtatcaa aggcaaaggt
     2461 tcgcgatgaa ccaatactct tctctccttt ctgacgttcc gggttcacag gtgactcata
     2521 cgttccatta gctgcctggt gaagatactc tcccttcttc ccgaaccagg agcgcagatc
     2581 ctctacaggc tgtgctgcca gctcaccaat tgtacgaata cctttgcgct gcaagcgttc
     2641 agcggtgctt tttccgcatc cgtgcaggct tccgaccgtc tgcggccaaa aatatgttct
     2701 atactgccga gcccccatct cgacaaaacc gcctggcttt tttacatccg cacacatctt
     2761 agcaatcagc ttcgtcggtc ctgccccgat actactcggt atgagtagct ccctgtataa
     2821 cttgtcttga atatactctg ctattatgcg tgctgtgtgt ccctttgcaa caagctcgct
     2881 aatatcaagg tatgcctcat ccacagaagc gacttcacag ggggcgatcc ggcgtaaaaa
     2941 acgcataatc gcttccgaat aacgccggta caaggcatgg ttcggctgca cgaacacagc
     3001 ttcagggcaa agcttccgag cccggtaaaa gcgcatggtc gtataaacac cttttgcctt
     3061 tgcatcatag cttgcagcaa caacaatccc cttgcgtttc tcggggtttc cggccacaat
     3121 tacaggctta ttgcgcagct gtggattata gctttgatga acagatgcga aaaatgagtt
     3181 catgtcgcat agcaaaatcg ttttctccac cctatccgct ccttttcccg ccttttctcc
     3241 cattatagaa caagaatata cgttcgttaa tatatacaaa gaaaatatct gctgattgcc
     3301 tgtaaaatat ttgataaaat aaaagtggaa agttcagcat gttatttttt atgatttggg
     3361 agggatggaa catggcagag aaataccctg tacttcaaaa tgcggagcct ttttatatgc
     3421 agggcggcga tatcggtgtg cttgtacaac acggtttcac cggcacaaca caaagcatgc
     3481 ggttccttgg ggagtccctg gcacaggtcg gattcaccgt atacgcccct cgtctgaaag
     3541 gtcatggcac gcattatgaa gatatggaag cgacttcata tgaagattgg atcacttcgg
     3601 cagaagaagg ataccaaaag ctgaaagcat cctgccgtga ggtttttgtg gtcggattat
     3661 ctatgggagg cacaattgct ctgcatctgg ctgaagagca tccggaaatt gcaggcatta
     3721 tgctaattaa tgctgctatc cgtgtcgaga atttcgaacc gctggccaat gagacggccc
     3781 gctatcttga tgctatcggt tcagatatca aagctcctga cgtagctgaa ctggcatatt
     3841 caaaaacacc ggtcgcttct gttaaacagt ttcttacatt caaaaacatt gttgcatccc
     3901 gcctctctgc cattacatgc cctgctctcg tacttgtatc ccgtgaggac catgtcgtac
     3961 cgcccgaaga ctccgattat atccttgctc atattatgtc tgagttaaaa gagaaagttg
     4021 tactggaaaa ttcatatcat gttgcaacac tcgataatga taaagaactg attgcccgac
     4081 aatgtgcggc ttttattagt gaaataaatc aaatgaaaac taaatcataa gcaatttcaa
     4141 tcccttaata aaaacaggaa aacggcggaa gcaaaactgt agctcccgcc gtttctcttt
     4201 tttactgcta tgcatctact cattctttct tttgttagcg gcttcctcta gcccgtcgga
     4261 aggatactgg gaacagagac tagaaaaaga cacactggcc tttcttctgc tggggcgcag
     4321 ggcgcatcca acctcttctt ttttccaaat ttcctacttc taaccacgtt atcatgtcaa
     4381 aatatcgagt gtaacttata tagatgaata gcatctcacg ttttggggat gactatagcg
     4441 attggaattt caaaaacagg agatatatta atgagaaagc caatactttt acttcttgca
     4501 gcatgcacca taaccgtgcc attcttaact tcatacccag catctgccat gcctcatcaa
     4561 actgaacaac ataacaatag cgtacaaccc caatccacaa ttgattcaca agccgaaata
     4621 acaaaaggcg gtagaggggg acgcggcgga gtcggtatca cccctcgaag accggcggac
     4681 ggagggtatc gttccagata tgaagctccc gtcacacggc cgaccccttc ttctggtata
     4741 ggacgcggac tatgggcgtt tggtctgggc gcacttttcg gaagcattct acacccgttt
     4801 agcggagctt acgggttcgg cttttccttt ataggcttgc tattttgggc tcttgtatta
     4861 tttatggtat acaaatattt tcgacgtttt ttctccagaa cgaaaacata ggcggcgttt
     4921 cttcaattta ggcaccctcg tcccagtacg tgcaatcttc acggtcattc actttatacg
     4981 aaatggtatg tcaagctttt tattttcttt aaaatggtat tattttttaa aaacgatgct
     5041 atactatgaa taggttacaa atattgaaac gtataattca catgttatta gggattgtat
     5101 tttcaatata ttgtccgtaa taatatgtga attttatttt tatggcaaat agaagttgca
     5161 tattgattaa attatttgga ggttcttaca tgaacggtac agtaaaatgg tttaacgcag
     5221 aaaaaggttt tggatttatc gaaagagaag acggcgacga tgtattcgta catttctccg
     5281 ctatcactgg tgatggattt aaatccttag aagagggaca acaggtacaa ttcgacatcg
     5341 ttgaaggaaa ccgcggacct caagctgcaa acgttgtaaa gctgtaggat aacagctcac
     5401 ttacaagctc aagatgccgg catctatatg tcggcatctt ttttaatgga taaaaaggca
     5461 ctatatgctt tcatccgata gtaatacttt cttagctttt tttctttagt tcttcctcca
     5521 gctttctcac ctgctgctgt aattgatcaa ttctttcgtg tgttccttga gcagaacggt
     5581 tgacgaccat accaacaatc gagataatac cgataaaaac aacaatataa aacattgccg
     5641 tccaaagata tatctccatc cctccagtta ttattacctt aacacatcat ttcagtaata
     5701 tataggaagg aaattgctgg actcttgtct atccttctat gccgtttcaa ttttccactt
     5761 taaagaggga attccggctt catcctcaaa ggcagcaccg aattgatata aaattgcttc
     5821 attcaaaggt cggctgatta attgcatgcc aattggcaaa cctgtggccg aaaaaccaca
     5881 tggtacagac aagcttggaa gccctgttaa attggttggt ccggttaaac gaagcaaagc
     5941 tgcacgaacc tgctctgtct gtccttgtat cttgatttct ctctggccga ttttcggagg
     6001 cagaatagga agcgttgggg ttaccagcac gtccacatgt tcaaaaatct tctcaaacga
     6061 ttccaaagct tgcctgcgaa ttgtttgtgc ctgcacatat tcatgtccct ttgcttccgc
     6121 gcttaacctc aggcgctcaa gtacttccgg atgaaagttc ccactctctt gtttaagatg
     6181 ttcttcgtgg acatcgtatg cttcgctctg cagtgttttt agctgtgccc atgaggtgcg
     6241 ggaaaggatg ggaatatcaa ccggcttaca ctgtgctccc atttcttgaa acatagctac
     6301 cgcttccttc atccgttcct ttacttcatc ctcaagacaa tcaaaataaa agctggaagg
     6361 cactccgatt acccttccct tcacactgtc tccaatataa cgggaaaaat cctcgttctc
     6421 gcttttacgc gagtatggat cttgtggatc ataccccgct aaaacattta atagaagagc
     6481 gttatctttt atcgttctcg tcatcggtcc gacatgatcc agagtgtaac ctaacggata
     6541 tacaccatgt ttactaaccc taccaaacgt cggcttcatt cctacaatcc cacaggccga
     6601 ggaaggaatt ctgatcgagc cgccggtatc tgttcccagc gcgccgaaac aaagcgcgga
     6661 agcaaccgcc actccagatc cactgcttga tccgccggac atatgattgg tgttatacgg
     6721 atttcgagcg gggccaaaaa aagaaacgtc tccggtaggc ccataagcaa actcatgtgt
     6781 attgagtttt ccaataagaa tggctcccgc attttttagc ttctgaacaa ccgttgcgtc
     6841 aaagtccgga acaaaatgat gatatatttt cgaccccata gtcgttctta tgcccttcgt
     6901 ataaattaag tcctttagtc caatcggaac accgtgaagg tagcctttcc actctcccct
     6961 tcctatttct gtttccgctt ttttggcgga agcaatcgct tcctcagaag caacagttat
     7021 aaacgcttga atggaaggat ttatttcttc aattcgtttt aaaagctgct tgacaatttc
     7081 aaccggtgag atttctttat tacgaatttt gcatgataga ttataaatat ccaactgcaa
     7141 aatatccgaa tttatcacat acattctcct ctcactattt tatatagcaa tcttagtcat
     7201 aaaaatagaa catatgatta ctggattatc gatttttctg aaatcgggtt gctcctttcc
     7261 agttcccgat tctccttatc ctttataggc gtacctacga cttttaaccg acggcctgtc
     7321 tttgtcgtct gtatcatgga cacctgctct tgcctttcca gtacaagacg ggtaatcgat
     7381 ggataaaaga ccccctcctt ctctaactca tatgtactct ttcctactaa atcttcttcc
     7441 ctatatcccc ataaggcttc acatgccgag cttacgcgca gcgtaatccc atctgcatcg
     7501 gaaacataaa tgacatcata aacaaaatgg aagttatctt ctatccatcc tgattggttt
     7561 atagacagaa aagaaaaaac atcacccaaa gaaagcggag ttccctcttc cgatgtaaaa
     7621 cgtagctgtt gagaagcaaa acgattcata tgaagaatcc gttcatcatg atctagtaaa
     7681 ataattccca atgaaatcga atcaaatagg ggaaaatagg aagattccca aagtgtatta
     7741 ttcatatggt ctctccttca tcgttcgtca ttattatgct catatcatta ttcgccagga
     7801 agattgcata gagcttcctt ttactaaccg tgtgatgctt tttctgctat tcctacccca
     7861 agcaacgcaa actccctgcc tattaggatt cttatgaaag gcttacactt gatatttcga
     7921 caggggagcg tggttggaag taagagatta ggaaaaagaa aggggtggat gcgccctgcg
     7981 ctccggcaga agaaaggcca gcatgtgttt ttccgaccac ccaccgccct tccttctttt
     8041 cttaccttcc accacaaaaa catgtcgatt tatcaactca gatgtatata taatgaataa
     8101 taataacaat attgctgaaa attctcactg tattatgcta tttttaaagt acacaaaaag
     8161 ccgttctcct ccaagagacg gcttctgtca ttcaccacgc aaccgctttc aacaatgacg
     8221 ataaacaatt gcttatacag ttatcccctg ctttacttcc atactctcta tgtagtcaat
     8281 tcctgcatga agtaaactta cattaaatcg tgatgaagta gcatcttcct gttccatgct
     8341 tataaatcca cgtttagcca aatatgtata agccaatagt tctgttctgg tctttacaag
     8401 tatactcatt gttttacttc gacttcgtag atgtcttaca taaatacctc tcaatacacc
     8461 taacctatat tctcgagacg taaccaatcc atccacctcc agccatattt ttcctatatc
     8521 caacaatatt atattttaaa tattagtaat aataaatagt taaccgttcg acaattttcg
     8581 tacttaagcc attcaggaat acattcaaga atcgcttttc aagattcata tctgttcaaa
     8641 tattctaggc gttccctacg acagggaacc ggtccggcgt atttataatc gcctgccaaa
     8701 gcggtgttga aatttcaaat gagcctgatc ggccgctcta tccaaatctt ccccagcgac
     8761 atcgcataaa taagattctc cctgcttact cgatacatct aaatatcctc cttttgcaga
     8821 ctaaaataaa tggaaatact ccttgcgctc ccagtcgctt atcgtacatt catagcgctc
     8881 aaattcatgc agacgtaatg ctgcatagtg ctcaataaaa cgagagccca aaaaatcggt
     8941 gaacacctta ttggctaaga gagcttcaac actattcatt attggtacaa atgaacagat
     9001 aggaggactt tatgtttctt tctttttcac atttctctac ttcatctata gatattcatt
     9061 caaaaaaccc taacttttct cgtacgctcc aaatgatcct tcgcgttgcc cagtatccat
     9121 ctactgcgct tatcgaggga gaaaccggta caggaaaaga aaaaatcgct acattgattc
     9181 atgaagcaag tccgcgttct atgatgccgt tcgtaaagat aaattgcggg gccatccccg
     9241 atgcactagc tgaatctgaa ctgttcggat atgagggtgg tgcttttatg ggagcaaaaa
     9301 aagaaggtca gtttcgggag gacttgtact accgtctgca ggtcgcgcac tttattattc
     9361 cagctctacg ggaacgtccg gaagatttgc catacctaat tgatctattt ctgtatcgtt
     9421 tttctgaaat atacaaaatg ccgataaaaa tattttccga agaagtaatg gaacgatttc
     9481 tacactacca ttggccagga aatattcgac aattacaaaa ttgcatcgaa ggcatctatg
     9541 caacaatcga acacgagaca gtgtgcctgg aggaattgcc tgcttttttg cagaacagtt
     9601 caaatatcca tataaagcct actggcttgc gagagcaggt cgccgctttt gaaaaacaaa
     9661 tcatcgagcg tgtactgcaa gaaacaaaaa gtttacgaca agcagccact attctccaca
     9721 ttccgcacgc cacattgcta cgacgtatcg aaaaatgggg gattcaaaaa aacaaggata
     9781 cttagaaata tggtaaggaa acgagcagtt cttctctcgt atttacatgc taagctagcc
     9841 ccaacaactc ctgaatttct tctttccgaa aaaataaacg cggattgctc cttacactta
     9901 tttaaaaatt gcatgattgt aatttaagtt acagttttat ttactcctca ttattattgt
     9961 aaagatgtaa agttcaaaca ataagaggag gaacataaat atggattgga atatggaaaa
    10021 attaaatgag gcagtaaaac agtttcagga aaaggctact attgatgcaa aatttcgcaa
    10081 gctagcatta gagaatccat caagggccgt taaacaatta acaggcttag aaataccaga
    10141 gggattcaag ctccacgttg ttgacaatgc cggtgcacat ttaactgtcg ttcttccaga
    10201 cttgaaagcg actgagcatg agttggatga agccgagctt caaaacgtag ccggtggtac
    10261 ttcgtttagc tcgtttatat tatatagcag caaagatcaa tactacagca gtcgcaaata
    10321 aacaaacgat aatccttgta ataggagaag ggaaaagaga acagggacgc cctagtaaaa
    10381 agggcgagca tgcttttccc acctctgatt tttccctcta cctcccacta caaaaagatg
    10441 tcgagaatac tcaatacacc tattcgttat ctgagcatat tctcttctcg taaattcctc
    10501 ttttttacct agatgaaata atttctaaat gtggtagttt atatagaaag aatcccccta
    10561 ggttcttttt cttgccgacc caggtcggcc ctttttttgc ccgtttgtcc tcttttcttt
    10621 cgcattttcc atctatcaga atatactagt agtatcccat tgttgagatt tcaccttcaa
    10681 gcgtcaattg ccggcctatg ccggcctttt ttattaatct tgtgcctccg aaacctttat
    10741 ctgccaattt cgtattacaa atacatagtt aatccaaagg agcttatatc aatgtcaaat
    10801 cgaaaaagct tttttcgttt atttgctaaa aatctcaaag aatcactggg tcctggccga
    10861 tatgaggtat atggcatcgt tgtcacgtgt ccccactgta agcacgatcg atttcagcat
    10921 ggatacgccc agttaaacac cgcctttatg accttattga accttgattt tgctaatcgc
    10981 tcagcagaaa cgctgacttg tgaacaatgt ggtaacatcc agtggtttaa caaaacggtt
    11041 aggccataca aatattagca tttcattgaa ctcctaccct tatgtgcttc cggatatgta
    11101 agaaagctta gctcgaaatt ttgatatagc tttaaaaaaa ttagggataa aaccacgtta
    11161 aggtttgcaa aatgctttca aatgaaaata tcgaaaaatt gaaaacagct gaaacctcaa
    11221 gggatttcag ctgttttttt cagtatctat ataaattaca cttgatattt tggcagagga
    11281 gtgtggctgg aaggaggaga ttcgaaaaaa agaacagggt ggatgtgccc tgcgccctgg
    11341 cagaggaaag gccagcgtgt ctttttccga ccgctcccgc ccacctccct tccttttttc
    11401 cttacctcct accacaagca tgtgtcgatg tatccaatca gatgtatata ccaggacaat
    11461 aaattttacc tttttaagca agaaagtttc aaatatgatt cgctaatctt ccctgctttc
    11521 ccgttgcctg ttaaaataag atggttaatt aatcatcaaa atcgaatgaa taatatttat
    11581 acgaagatgg tcgacatgat gagtatagat gagacgactt atcatgacat ttgcatgatc
    11641 tctcatggca gtcatatgcc ttatcatggc atttacacga tctctcgcga cagtcatatg
    11701 ccttatcatg gcatttacat gacctctcgc gacagtcata tgccttatca tggcatttac
    11761 atgacctctc gtgatagtca tatgccttat catgacattt acatgacctc tcgtgatagt
    11821 catatgcctt atcatggcat ttacatgacc tctcgtgata gtcatatgcc ttatcatggc
    11881 atttacacga tctctcgcga cggtcatatg ccttatcatg gcatttacac gatctctcat
    11941 ggcaatcata tgccttatca tgacatttac atgatctctc gcgacagtca tatgctttat
    12001 catgacattt acatgattca tcatgacaat gattattttt gtctctacaa cagttgtctg
    12061 aacagctgct atcgtgaggc ttgcgtacat gaaaattgtt cataccctta taataggacg
    12121 gagaaacaca aaaccttcta gtcaaaagct tttccctccc tctttttgct atataatatg
    12181 aaaagttgtc cgattttgta acgtcttgca tagttgtcta ccgtccaatt ttagggttaa
    12241 aaagtaatat gtgcacagtc cccgatactg taaacacccg cagctccttt gacacggtag
    12301 cttgcatcca caatgatccg gccatcaggc gtgagtggca atccaaaact acggagtgtc
    12361 ggattcggca gtagaccaaa tgtccaaaca cataagaaca cctttctaag atgataaggt
    12421 tgcttgtcaa ttagaataat acgcaacggc gtcccataca tgcttttcta atggcgttta
    12481 tagcattaag tccggcgtat ccgcctccaa ttatgatgca tgttcgttct ttcatacaaa
    12541 tccactcctc ctagctggtt tgcacatata acgacataca gatttgtttt gtgacatgaa
    12601 cataaaaaat tagctcaatt ttgctcccaa tcaaggtttt ttattgttct tacattcttc
    12661 cccttcctca cttcattcac tttcttcatt tactttttta actaaatatg gtatattaag
    12721 ggcgtaattg tttcacaaac aaccttcttt tcattgccga ccctgtgtcg gcctttttac
    12781 ttcacggtat attccgtagc acgagaaatg acttcgatat tttatttatt ttgggattag
    12841 gacttgttca aaaaatgata aaaagccgct tcgaggggcg gctatgtgat aaactactaa
    12901 tgttttttag aagagctttt ctggagatgt ggcaattcgc catacaccat ttactttttt
    12961 tacctttatc gttttaattt ccggttttga ttgatgctca ggataaggga tagataattg
    13021 atattccttc attgttgaag agcctttaat caattttgct gtagctttat taaattccag
    13081 aatgtttcct ttatccgcat ttacttgtgc cattctccct ttgtactcaa taaaacgctc
    13141 ttttatatat gtttcacttg cttcttttgt gaatgccttc attaaataat caagcagctt
    13201 ttttcttgtc ccaatatcag aagaaagata gcgatactga gaatctttta tattgaatac
    13261 ttctgttttt cctttgccac cacccaaagt gtaaaaatat cggttttctg cttctacaag
    13321 taacgaaatg atgttcttct catctatttt ttttatttgt gtaggacttg cagcttgttt
    13381 tttaacggct gctgtaactg gttctgcaat aacagggtta acagaaagaa aaccacaaga
    13441 caacactaaa caactaatta gcatttgttt tttcatgttt acatcctcct ttgactttct
    13501 acccttataa acgaaaaact aaaggaaaat gtttctatat acatctgatt taataaatcg
    13561 acacatgttt gcggtgaggg gtaagaaaag aaggaagggc gatgggcggg aacggtcgga
    13621 aaaagttacc tctatctatt ttccgctcaa ggacaaaaaa attacactca atcaattaaa
    13681 aactgtatac agcaaaccaa ttcagcaatt tttaaaaacc aaaaataggc tatagcaatg
    13741 tttaatagag aagaacggaa tttagtacgc caactctatc aaaaacctta ccaaagcatt
    13801 ctaaataaat tgaaaccaaa aacccggcac aatcggaggc cgggtttttc agcctgtcat
    13861 ccagctttca gaagtctgtt ccctgtacta attgcatgcg cacgcaataa tgaccaagag
    13921 aataaacaga acaagaataa ccccaatttc cattccttca ctacagaatc ccatacgttc
    13981 atccctccat atatgattga tttacttaca cttcatacta tgtggataca tatggacagg
    14041 tgttaggtaa atacccttat tcaaagcttt aggttttcta ctgacaaata gaataacgtt
    14101 cccttgcact attaatgtat ttcttttatc tcttaaggta gtaaaatctc cccatttcct
    14161 tcaacataga taatgtattt acgctacgca tttctttcat tctacttatc cttttcatcc
    14221 actttttacc ttcctatata gaaatcactt gacgtagtaa caaattatcc ttgtacatag
    14281 acacggcttc gggccagctc actcccgcac tattcatctt attaatggaa gggaatggga
    14341 atatagtagc atgtagattt ataataaaga ttgataatag ttggttaatg ataaagattt
    14401 taatcgaact ttattttaaa tcaacagtat gctaatatag tagcataaat agacaggcag
    14461 tcggtttata taaaggagtt gtaaaaatga gagttataaa aaaagccgag gagcgcagga
    14521 acgaaatact tgatgcggct gatgagcttt tcggtcagaa gggctttgat ggtacaagta
    14581 caaacgatat tctcgaaaag gtcggaattg cacgaggaac gctgtattat cacttcaagt
    14641 cgaaggagaa tattatggat gcactgattg agcggtatac ggtcctcctt ttaggagcag
    14701 caaaggaaat tgctgcagat aagagcatac ccataaatga gcgtattatc cgcgttgtaa
    14761 tggcactgaa cataaatgac ggaaacggca aggaaattat tgagcatatt cacaagcctc
    14821 agaacgcgct tatgcatcag aaaatacaaa aggtcataat caacagcgtt ccaccgatac
    14881 tgacggaaat aatccgtgag ggcattgaac aaggactatt cagtacgccg tatccgtatg
    14941 aatgcatgga aatggctgta gcatatacga ataccatttt tgatgatgat atggttaata
    15001 tgacgaatga ggagcgtgct tcacgtatac aggcgtttgt tttcaacata gaaaggttgc
    15061 tcggtgtcga aagcggaagt cttatgtaca tgatgaagat gtttgacagc ggaaatacag
    15121 gtagaagaaa taaaaacagc aatgaataat tcgggaaaat tcttcagagg attttctctt
    15181 ctctgggaag gacggtgggc ggccggaaaa agacacgttg gcctttcttc tgccggatcg
    15241 cagggcgcat ccaccttctt cttttttccg aatctcctac ctccaaggca aaataaaaag
    15301 ccactccgaa gggtgactaa tgtaacaaat cattcctttt atccatgtat acagtaccat
    15361 cactttgtag ctcagcataa aacacctctt catgtgagct gactccggct ttctgtacct
    15421 gctcatctaa ccatgccaca cttaagttta agtctttaag atttttatgt acaacttccc
    15481 catctacaat taactccgtt ggtacatata ttaatggttg tgcagcaata tttatcccct
    15541 tgtttgtagg cgtttgatgc tctggcttct tcagaataga caattgtcca tcaggctcta
    15601 gaatagcgta ctctatttcc tgaacggaaa aaacaccctt ttcccgcagc atcatactta
    15661 aatcatccat gttgtagtgt gcatctcgca tggctccttc caaaactttc ccctttttta
    15721 ccacgatagt tggttcgcca tctaatagaa cacgtgctct tggcgacttt aatccaatgt
    15781 agcctataag aaatgttaat actgtccaaa tcatcaagct tactatacct tcgacaatag
    15841 gaatgcttct gtccatcgcc atcacagctg caattgaacc aaacgtaatt cctgttacat
    15901 aattgaagaa tgtaagctca ctaacttgct tttttcctaa aacgcgtgtc ataacaagta
    15961 atatgaaaaa agctaatgta gttcgtccga gagtttccag cacattcatc cctatccttc
    16021 ctggtaattt tacagcttct ttttccccag gcgtttacaa gaaaaccgct cccctatata
    16081 cagtggtgtg aagtacgaaa aaaggataaa gtcagaaatt agacaaaaac acgtcaatct
    16141 tttttctgtc ggggcgcagg atgaatccgt cctcttcttt ttccaatttt cctacctcaa
    16201 atcacctaac ctttgttatt acgtcaagtg aattctatat agaacaacaa ggatggatag
    16261 aaaagagtga tgcatacggc gtgcgccctc tttgtttttc tatgtggagc gtgtggcgct
    16321 aagaacgaag gaacacgccg acgcgtgcac catacttgct ccagtatatg gataatcaac
    16381 aggtgcgata gaacaattct cctttttatt tccgcttctt tttacgttcc catttttctt
    16441 tttgcttttc ccaatagcgc tgcacacata cttcccagtt gcttttcgga ttaggcaata
    16501 taactctagt tttcatctgg attccccctt gatttatttt ccaattttat tatgtatcaa
    16561 gagtctattt tatatgacta acacttgtcg tcaaattccg aaacagcagt acttttttgg
    16621 ataagtaatg acgagagtgg acaataaaaa agccactcct gggagtgact gctataaatt
    16681 tttttctgtt tagacaaaaa gctttccata agccagacct accaatccta atagccctat
    16741 ccatccccaa ttgccgcctc tattagcatt tgtagccgta gttcgataat tatcaaacag
    16801 cgcaccaaaa ttatgtcatt ttcacgtcac tctccctcca acacccactc cagtatttct
    16861 gttaaatgag ttttatatcc agtgaataac tgtataccca gttccacata ataatggata
    16921 caaaaacgac agataacaca aataaagcgg gaatcataca tgaacaaacc acgaagaaac
    16981 ggaattacgc tgttacaata tattcttggc gttaatgtaa cgcagatagg aacaagtatc
    17041 ttaaccctcc cttcagaatt agcaaaaatg gcaactacgg atggatggat ttccattgtt
    17101 gtcgggtgga tgattgctac aatcgtgagt ttatgcataa ttggtgttat ggcaaaacat
    17161 ccaggggcca ctatatatga tgtgctcaca cattacctgg gaaaatggtt tggaggggca
    17221 tggattatca tcttgatgtg cagttcctta tttattgcca tgattgtttt ttatgaagta
    17281 ttaagattga tcaaattatt tattttacct aatacatcca gcggtctgtt agctattttc
    17341 tttatgatcc caacgtatat ggttctccgt agtggcatac gaatttttgc gcgatatgcg
    17401 gaatttgtct ttttctttac actttggctc cctattttat tattggtacc cttaaaagat
    17461 gccgaattca tttttatgct gcctgtgtta aaagagggaa tgctgcctat tttacatgca
    17521 gtggctcctg ctgttatttc atttattgga tttgaaattg catttattct ttacccttac
    17581 ctaaaaaaca aacaagcagc agcaagaggt attgtcatcg caaacaccat taccttgctt
    17641 gtttatttgc aaattacgtt aagttgcttt ctttacttta gcccagatga aattaccaat
    17701 ttgttatggc ccacacttac actcgtaaaa ccaattcact ttcctttttt tgaacgattt
    17761 gaaatcctat ttttgtcgtt ctatatgttc attttctcaa cctcattcct tccgtccatt
    17821 tttattgtca ctgaaaacat caaccaattc ttcggcaagc aaaattggca gctacccata
    17881 tgtattttgc tatcacttat actcgcggct tcctttgttt atatacctac ccatagccaa
    17941 cttgaagtaa tgagcaaatg gtggaactgg gacgcttata ttgtattttg cgtctttcca
    18001 gtcttgtttt ttctttacgc tactttatat acacgatgga aacaaagaaa aaccgtataa
    18061 aaaactgcac caaatagcat accccaaaaa ataagtacag ctacaaattt tgataaaacc
    18121 taactctctt ttccgcgtta attaattcta tattactctc catataaaaa gccgctcggc
    18181 gggagcggtc ggaaaaagac atactgtcct ttcttctgcc ggagcgcagg gcgcatccac
    18241 cctcttcttt tttccgaatc tcctccttcc aaccacctga acttttgtta ctacgtcatg
    18301 tgatttctac atagatatcg tacagattgt ttttgctcca tgaaatattc cccgtatttc
    18361 ctccatagtt cttttattta gcgtgagtag gtcctcaaat catattctat atctcccccc
    18421 tttgcagata aaaaagattt cgtccttcat aagcctgtag cagggcatat aatcttcctt
    18481 ttcctatcta cgtcaccctt caccagcaag gcagccttaa gataaacgaa tgatggttag
    18541 agcagcccca gctgatcctc cccctactaa gacagccgta gctaccaaac cgaataactg
    18601 aagtgcaatc gtgtccccaa cgtttaagga gataataaca ttattattat agcttgaagt
    18661 agctacagct ggagacagta tagaaccggg gattggagtg ccgtttcgag taagtcttgc
    18721 acctacaagc aatgcggttg tagtattaat ttggtacgca agataataac gcccgtttgc
    18781 tggaacagta aagatagcat taccggaatt aactgtaaaa ctctctaaat tttgattgtt
    18841 aggaagagcg acattgatcc cccctgccac aactagaatc gtgcttcctc ctgtattgga
    18901 tgcatacata gaagtagcag tagcgtctag tggactgata attctagtta tataagaaga
    18961 aaatttttcc cacacagtaa gtttttcact ccgttctctc ataaattatt atttttaact
    19021 tccctccgaa agaagtctcc cacttataaa cgtcaaggtg cttttagcac cagtgaaagt
    19081 gggagatgaa tttaggcgta gcctaacgtt attgtaatca tagtataata aaacaaatgt
    19141 tcttatagaa aatagataag tggtttccct catctaaaac gtgttcctgt tgcggtcaag
    19201 tagaaggggc cctcgctctt tctgaacgta catttgccgt cctttttcgc ctggccgggg
    19261 catgcgctcg ggaagggaga cgaaaggcct tgtttgtgtc ccgttgtggt ggccttttcc
    19321 tctttggaca atcaacatcc ttggtatcca taaatggata gaaaagagtg acgcgtacgg
    19381 cgtgcacctt ctttcttcca ccttatggct aatcaacaga cgtgtatcat catatacaga
    19441 gcatggaatt ggctcggtag ctaagtaaat ttcgtaccgt taggcgcgac tgccttagaa
    19501 gcccccacct ctagcaaagt gtaaatggtg ggtagtttac atttgatatc ataatatgtt
    19561 ttactgtaaa ttttgattag ataattgcca tagtaagagt tgaaaaataa ttcacaggta
    19621 ctgcactgaa ttgtatgctt ttttgctact aaagtacgga aaatagataa caaataaagt
    19681 cgttccagct agaacgactt tatttgtatt gttgtatgct attttaaaat ccctgtatcc
    19741 tgagtcattt ttgtattcat tagctttttc tctatgtaaa atacaaggta ccatgacctc
    19801 ttatggtgta cattattaac attaaaacac atgaatgctt tcaatttttc cataaccaaa
    19861 aaccacttca gtataagctc ccgggaaatc tgtattttta aaaagaactc ttttttgctt
    19921 aagttcatcc tcaataatac catccttacc ccggctcatt aaatcctttc ccaatttctc
    19981 ttcaaagccg gcacattctt cactaagaaa tacctcgttg ctcttcgttt gaagcagtac
    20041 gcctgaatct ttccatcctt tgctgacagt aatcgtatct ttctttaact taattcttca
    20101 ttcctctaat aacaatcgac agacaaatca caatatttac cacccaaaat tcgtttgtat
    20161 atatgttagg atagaacatg agttagcaaa caatacattc tagtttagga gtggtcaaat
    20221 gaaaaagcta ctagcaaccg tcactattct tggtgcatct ctactaacct ttggtgcagg
    20281 aagcgcaagt gcggcaacca actgcccatt cgtaaacgga g
//
