LOCUS       c00001_NZ_JPOI..        9281 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_JPOI01000001.1 Geobacillus vulcani PSS1
            N685DRAFT_scf7180000000002_quiver.1_C, whole genome shotgun
            sequence.
ACCESSION   NZ_JPOI01000001
VERSION     NZ_JPOI01000001
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 15:42:53
            Original ID  :: NZ_JPOI01000001.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 534690
            Orig. end    :: 543971
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..654)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 132.7; E-value:
                     2.8e-40)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_569"
                     /transl_table=11
                     /translation="MQAKLVVKNLTFSYDKNNIISNLSLTIKSKDRVCIIGDNGSGKST
                     LLKILSGIIHTDCSIYFEGKPLSNLLEYKKRIAYIPDKPYLYDLMTGKENLKLIENLWD
                     IKDKDNYWKKVYDLCEVFNMSSYLNELVQNYSLGMKHKLFFIAMFARETGLMFLDEPFT
                     ALDQKSQNIAINLLKTYSQNGGAILFVSHLKELQYELATRFYEMSNGKLKELEQ"
     protocluster    1..9281
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[539628:539949](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(4939..5259)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..9281
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..9281
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="2"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     PFAM_domain     complement(169..594)
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_569_0010"
                     /evalue="4.60E-22"
                     /label="ctg1_569"
                     /locus_tag="ctg1_569"
                     /protein_end="162"
                     /protein_start="20"
                     /score="79.1"
                     /tool="antismash"
                     /translation="SNLSLTIKSKDRVCIIGDNGSGKSTLLKILSGIIHTDCSIYFEGK
                     PLSNLLEYKKRIAYIPDKPYLYDLMTGKENLKLIENLWDIKDKDNYWKKVYDLCEVFNM
                     SSYLNELVQNYSLGMKHKLFFIAMFARETGLMFLDEPF"
     CDS             complement(644..1201)
                     /locus_tag="ctg1_570"
                     /transl_table=11
                     /translation="MKMTIWLNPSLFFIKKNVTPNKLLFFNLFVLLFAMMFLELWVANV
                     LDIHQPKKIIGFFLVATFITIPFYYIINFIFSVLLGIILVILKKDFSVLRLYTVVLSAN
                     SFIFLFNAATLYIIWINNAPQLFYTLTITLLLIVNILYIRILYFGLVNYVGVTKKISFI
                     IAAIILFITFSTTSYGVVHYAS"
     CDS             complement(1245..1775)
                     /locus_tag="ctg1_571"
                     /transl_table=11
                     /translation="LNKMLQGIIKRWKRVMLLCILIFSVSVLIGIVAGFLGDYSTFRPK
                     EAEMLDIFVNNTKICIFIIVSGLLTGGVLSSIVLIINGYIIGIVIYGAIADYGFLPILT
                     GLMPHFFIELAAIVSCATVGFMSSISFLMCIGKWSKLPLPRLIKDGTILILIAILLLLF
                     ASWVESNISKVVL"
     PFAM_domain     complement(1260..1718)
                     /aSDomain="SpoIIM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01944.19"
                     /description="Stage II sporulation protein M"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_571_0011"
                     /evalue="2.10E-20"
                     /label="ctg1_571"
                     /locus_tag="ctg1_571"
                     /protein_end="172"
                     /protein_start="19"
                     /score="73.5"
                     /tool="antismash"
                     /translation="ILIFSVSVLIGIVAGFLGDYSTFRPKEAEMLDIFVNNTKICIFII
                     VSGLLTGGVLSSIVLIINGYIIGIVIYGAIADYGFLPILTGLMPHFFIELAAIVSCATV
                     GFMSSISFLMCIGKWSKLPLPRLIKDGTILILIAILLLLFASWVESNIS"
     CDS             complement(1768..3525)
                     /locus_tag="ctg1_572"
                     /transl_table=11
                     /translation="MSIFRLIILLINVRIKQQYSLISKYRPILNKLKPTSIFTLSLLSR
                     IILSIIGLFALIIYFYNEKYSFYWECTLIMVFIGMHFFNGLISYRRTHTPILVSLFTMA
                     PRNARTIHNILLIEEILWLALNQCGFYLAVFIFFLYINKFQWISSSLAYILLVLVSILL
                     FIISNKLFGMYVRNKIINPIGIFRFFAYFMSIVICFLLGFCLVKFMLFPLIATVKENID
                     SYNDILNDNVWNNIISILEEQWLTSIIGFIRTMYSFVLFNFICYQFKNFNYWGALSLFF
                     SGFFIYIVLFFTNPKFIDENQNNNLYKCRDFLHFYCIFLRKLNYLIFKNDALTNKEVLL
                     LERNRWIVSPVAFSLIFITLESSFYFGFIFSLINLVKSTDTKLLLIFTLNLLILTNHCF
                     ELREEFPVLFLLSAEKNNINLFKISARSIKDLYIAKKRLMQLILFIPFLIVLIVNSILY
                     IRGHIYSLGYLVILIALVNAYWITPLFQLYMSPMFAKFNYTNVIEVGKTEEEAKLYLRA
                     QGLPRKFILLPFLVILYMNLFISFPNVLTKWLLVIFFLYFMSSSLIFAYIAQKVIQKGI
                     SKIEKEVIE"
     CDS             complement(3546..4517)
                     /gene_functions="other (smcogs) SMCOG1130:transposase
                     (Score: 339.3; E-value: 3.7e-103)"
                     /gene_kind="other"
                     /locus_tag="ctg1_573"
                     /transl_table=11
                     /translation="MYQSGVSIREIGKFIERILGNAYSPATISRITDVVKEDIEKWHHR
                     PLSKRYSVLYLDGLYVKLHRDTVEKEVIYVVLGVNEEGYREILDFFVGGQESAYVWQEI
                     LQQLYQRGVKEVLLGVFDGLPGLEEAFKAVYPKADVQRCVVHKVRNTLNRVRKKDQFKV
                     AEDLKLIYRAPNKEMAFQMFQQFESKWFGKYPREVQSWANELDVLLTFMDDPSSIRSVI
                     YTTNAIERTIKEIRKRLKPMNRLSSLEAAEKVVYLTIQDFNEKWAGRTLRGFAEAQQAL
                     QRMFEEHFQKSVHSYLAKTVQFFSSVTQWRGQCICLLFQYIT"
     PFAM_domain     complement(3717..4517)
                     /aSDomain="Transposase_mut"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00872.20"
                     /description="Transposase, Mutator family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_573_0012"
                     /evalue="4.90E-74"
                     /label="ctg1_573"
                     /locus_tag="ctg1_573"
                     /protein_end="267"
                     /protein_start="0"
                     /score="249.6"
                     /tool="antismash"
                     /translation="MYQSGVSIREIGKFIERILGNAYSPATISRITDVVKEDIEKWHHR
                     PLSKRYSVLYLDGLYVKLHRDTVEKEVIYVVLGVNEEGYREILDFFVGGQESAYVWQEI
                     LQQLYQRGVKEVLLGVFDGLPGLEEAFKAVYPKADVQRCVVHKVRNTLNRVRKKDQFKV
                     AEDLKLIYRAPNKEMAFQMFQQFESKWFGKYPREVQSWANELDVLLTFMDDPSSIRSVI
                     YTTNAIERTIKEIRKRLKPMNRLSSLEAAEKVVYLTIQDFNEKWA"
     CDS             complement(4939..5259)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IId"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_574"
                     /sec_met_domain="Bacteriocin_IId (E-value: 2.3e-17,
                     bitscore: 60.5, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MILIENKLTQLFILLFAGISIGGLYFFMLTFLPVADLAKEFGVPA
                     WAAAWILTALDASTTVTAIVSFLTALGTGGLSLIAAAGTMGIKKYLKEELEKRGKQAFI
                     AW"
     PFAM_domain     complement(4942..5142)
                     /aSDomain="Bacteriocin_IId"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09221.12"
                     /description="Bacteriocin class IId cyclical
                     uberolysin-like"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_574_0013"
                     /evalue="1.40E-07"
                     /label="ctg1_574"
                     /locus_tag="ctg1_574"
                     /protein_end="106"
                     /protein_start="39"
                     /score="31.7"
                     /tool="antismash"
                     /translation="EFGVPAWAAAWILTALDASTTVTAIVSFLTALGTGGLSLIAAAGT
                     MGIKKYLKEELEKRGKQAFIAW"
     aSDomain        complement(4942..5154)
                     /aSDomain="TIGR03651"
                     /aSTool="tigrfam"
                     /description="circ_ocin_uber: circular bacteriocin,
                     circularin A/uberolysin family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_574_0005"
                     /evalue="1.30E-15"
                     /identifier="TIGR03651"
                     /label="ctg1_574"
                     /locus_tag="ctg1_574"
                     /protein_end="106"
                     /protein_start="35"
                     /score="55.5"
                     /tool="antismash"
                     /translation="DLAKEFGVPAWAAAWILTALDASTTVTAIVSFLTALGTGGLSLIA
                     AAGTMGIKKYLKEELEKRGKQAFIAW"
     CDS             5494..5658
                     /locus_tag="ctg1_575"
                     /transl_table=11
                     /translation="MNQNLWDVLQELLEKDGIGATELALAKERLSPQEFSALAAYLQDS
                     SKKEGNLWV"
     CDS             5665..6615
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182:Polyprenyl synthetase (Score: 82.5; E-value:
                     4.4e-25)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_576"
                     /transl_table=11
                     /translation="MNRIEKSTIRAFLQNHLLTSCMLEKEIIQYIFHLLHGKGKILSTN
                     ETHFSWGEFYAQVSTFHLKDDTCIQSIISHAAAIELLILATDIFDEISDHDQSDQVVSQ
                     LTTGEAVTIANALMMEAFRLILHNSKEDIQEKLSIIISELQNACNGQWKDLHFIISECI
                     PTEEDYFSIIKQKSSSLVKLVCELSDMPNRHIWETIAMDIGIAGQLKNDARDIMSDDKS
                     DLTNKKATLPFIKAIEYSSKKDNGWLVRKLGQLKEANNNSQLIKEIRNYIQKTGAIDYC
                     LILSKIYMDKAFRQIATHFPDKQIQIARLKRYLES"
     PFAM_domain     5857..6468
                     /aSDomain="polyprenyl_synt"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00348.19"
                     /description="Polyprenyl synthetase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_576_0014"
                     /evalue="3.30E-15"
                     /label="ctg1_576"
                     /locus_tag="ctg1_576"
                     /protein_end="268"
                     /protein_start="64"
                     /score="56.0"
                     /tool="antismash"
                     /translation="DDTCIQSIISHAAAIELLILATDIFDEISDHDQSDQVVSQLTTGE
                     AVTIANALMMEAFRLILHNSKEDIQEKLSIIISELQNACNGQWKDLHFIISECIPTEED
                     YFSIIKQKSSSLVKLVCELSDMPNRHIWETIAMDIGIAGQLKNDARDIMSDDKSDLTNK
                     KATLPFIKAIEYSSKKDNGWLVRKLGQLKEANNNSQLIKEI"
     CDS             6623..8710
                     /gene_functions="regulatory (smcogs) SMCOG1048:sensor
                     histidine kinase (Score: 142; E-value: 4.4e-43)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_577"
                     /transl_table=11
                     /translation="MNKKVLPFSLILISIFVICYFLLKMYNEHVSPQRYFPIFIGMIFL
                     LAGIYSYVQKPNSIVIQYFLALMFISGMALALSIPSSENIKPARELEVVFISFAPYILL
                     KFFEHFPSSAKPNFFRQVRILTLYTAIFITISYLFIGIHHRVIISTIIRPCIVANIILA
                     LLGCVVLFYLHLRSNSNKIKNQIYLLIGSIIISFAPVVILNLIPNAFFSLPGAPFHYSL
                     GSIVMFPLTLSYLLTRQEIIDFREILEKMMVRLFMIGCCLAIFNLLLSLFYDIHFKLGI
                     LINTLLICLFIVYDLIDKGLEPLQMRKWHGKQEEIQKEKLAILQELLNGKHLEYCAKLI
                     ADLIHKTIDVSGVCIVWKHDHSPTVLHKTGMFRHFHDSELLSYACQSSHFYKMTMNEKS
                     VFFYPMNIDDALIGWMMIGEKTNATVFDKEEQKLMKKIQMDAIELFASSKTLQQIENQL
                     KKTIEESWMSEQSHWLLLHEHEEEKRKLSIFLHDEVLQHLILLLNKLEWLIQKKNIDKR
                     LFDDIKGLLQRDIFEVREMCHELYPVMVEDLGLKQSLSSLRRTCEMNYNVIVEVNYIAN
                     LKIIPPFLSIQAFRIIKELVYNAIKHSSSRKIVVTVEETQQFLSIQVKDYGVGFKVPDH
                     LLELSQTNHLGLITIQKRVHQLKGTLTIHSELGAGTCISVSLPITVEEGGVNENQNIIS
                     R"
     PFAM_domain     8381..8659
                     /aSDomain="HATPase_c"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02518.28"
                     /description="Histidine kinase-, DNA gyrase B-, and
                     HSP90-like ATPase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_577_0015"
                     /evalue="2.30E-09"
                     /label="ctg1_577"
                     /locus_tag="ctg1_577"
                     /protein_end="679"
                     /protein_start="586"
                     /score="37.8"
                     /tool="antismash"
                     /translation="QAFRIIKELVYNAIKHSSSRKIVVTVEETQQFLSIQVKDYGVGFK
                     VPDHLLELSQTNHLGLITIQKRVHQLKGTLTIHSELGAGTCISVSLPI"
     CDS             8682..9281
                     /gene_functions="regulatory (smcogs) SMCOG1016:LuxR family
                     DNA-binding response regulator (Score: 126.6; E-value:
                     1.3e-38)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_578"
                     /transl_table=11
                     /translation="MKIKILLVDDHLLVMHGIQQLLENEIDLEVVNTVCDPALLETEIK
                     KHNPNVIVMDIRMKNDNGIEWTRKIAKTYPTCKVVILSGYGYDEYIQAAYEAGAYAFVT
                     KENSVFELANAIRQTYLGVKSFPIDRLDRYNCPLTKTEWNILQLISEDKTNAEISELLH
                     ISRRTVEHHVSSILRKLEADSRVGAVVKAIKLGLIG"
     PFAM_domain     8694..9029
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_578_0016"
                     /evalue="9.40E-25"
                     /label="ctg1_578"
                     /locus_tag="ctg1_578"
                     /protein_end="116"
                     /protein_start="4"
                     /score="87.1"
                     /tool="antismash"
                     /translation="ILLVDDHLLVMHGIQQLLENEIDLEVVNTVCDPALLETEIKKHNP
                     NVIVMDIRMKNDNGIEWTRKIAKTYPTCKVVILSGYGYDEYIQAAYEAGAYAFVTKENS
                     VFELANAI"
     PFAM_domain     9090..9257
                     /aSDomain="GerE"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00196.21"
                     /description="Bacterial regulatory proteins, luxR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_578_0017"
                     /evalue="2.90E-17"
                     /label="ctg1_578"
                     /locus_tag="ctg1_578"
                     /protein_end="192"
                     /protein_start="136"
                     /score="62.1"
                     /tool="antismash"
                     /translation="PLTKTEWNILQLISEDKTNAEISELLHISRRTVEHHVSSILRKLE
                     ADSRVGAVVKA"
ORIGIN
        1 tcattgctct agctccttta gttttccatt tgacatttca taaaatcttg ttgctagttc
       61 atattgtaat tcttttaagt gactaacaaa taaaattgct cccccatttt gactatatgt
      121 ttttagtaaa tttattgcga tgttttgaga tttttgatct aaagccgtaa atggttcatc
      181 aagaaacatc aaccccgtct cccttgcaaa cattgcaata aaaaacaatt tatgcttcat
      241 accaagggaa taattctgaa ccaattcgtt taaataggaa ctcatattaa atacttcaca
      301 taaatcatac accttcttcc aataattatc tttatctttt atgtcccata aattttctat
      361 aagtttcaaa ttttcctttc ccgtcattaa atcataaaga tacggtttat caggaatata
      421 agcgatcctt tttttatatt ccaataagtt agacagaggt ttaccttcaa aataaatact
      481 acagtctgta tgaattatcc cactcaatat ttttaaaagt gtagatttac cgctgccatt
      541 atcgcctata atacatactc tatcttttga ttttatagtt agagataagt tgctaatgat
      601 attgttttta tcatatgaaa atgttaagtt tttcacaact aacttagctt gcataatgaa
      661 caaccccgta actagtagta gaaaacgtaa taaagagaat aatagctgca atgataaaac
      721 tgattttttt ggtaacccct acgtaattaa ctagtccaaa atataaaatt cgtatatata
      781 gtatattcac aattaataat aaagttattg ttaaagtgta aaataactgt ggtgcattgt
      841 taatccaaat tatataaaga gtagctgcat taaatagaaa aataaaggaa ttagcactta
      901 atacaacagt atacaatctc aaaactgaaa aatctttttt taaaataacc aaaataatac
      961 ctaacagaac tgagaaaata aaattaataa tatagtaaaa tgggatagtt atgaatgtag
     1021 ctacgagaaa aaatccaata atcttttttg gttggtgtat atctagtaca tttgccaccc
     1081 atagctctaa aaacatcatt gcaaatagta aaacaaataa gttaaaaaat aaaagtttat
     1141 tgggtgtaac attcttttta ataaaaaaga gactagggtt caaccaaata gtcatcttca
     1201 tgccataccc cctttgtatt atttgtattt aagtcacaga gattctagag aaccacttta
     1261 cttatgttac tttctaccca actcgcgaat aacaacaata aaatagctat caaaattaga
     1321 atagttccat ctttaatgag tcgaggaaga ggaagcttac tccattttcc tatacacatt
     1381 aagaaagata tacttgacat aaatcctact gtagcgcagg aaactatagc agctaattct
     1441 ataaaaaaat ggggcattag tcctgttagt atcggcagaa atccgtaatc cgcaattgcc
     1501 ccgtatatta caataccaat tatgtatcca tttataatta atacgattga tgataaaaca
     1561 cctccggtta acaatcccga tacaataata aatatacata tttttgtatt attaacaaaa
     1621 atatcaagca tttcagcttc tttaggccta aatgtactat aatctcccaa aaaacctgct
     1681 actattccta taagtacact aaccgaaaat attaaaatac atagtaacat aactcttttc
     1741 caacgtttaa taatcccttg caacatctta ttcaattact tccttttcaa ttttcgatat
     1801 tcctttttga ataacttttt gtgcaatata agcaaaaatt aagctactgg acataaaata
     1861 gaggaaaaaa ataactaaca accattttgt tagtacatta gggaaactaa taaataaatt
     1921 catatataaa ataactaaaa aaggtaataa aatgaacttg cgcgggagac cctgtgccct
     1981 taaatacagc tttgcttctt cttcagtttt acccacttca attacatttg tataattaaa
     2041 ttttgcaaac ataggagaca tatacaattg aaacaaaggc gtgatccaat atgcattaac
     2101 taacgcaatt aaaataacta agtaacctaa agaataaata tgaccgcgaa tatataaaat
     2161 tgaattaact atgagcacaa taagaaaagg tataaataaa attaattgca tcagtctttt
     2221 tttggctata tataaatctt taatagatct tgcagatatc ttaaacaaat taatattatt
     2281 cttttccgca ctgagcaaaa ataataccgg aaactcttca cgtagttcaa aacaatgatt
     2341 agttaaaatg agcaaattta atgtgaatat tagtaataat ttggtatcag tggatttcac
     2401 taaattaatt aacgaaaaga taaagccaaa ataaaagcta gactctaatg tgataaaaat
     2461 taaagaaaag gcaacgggag atactatcca tctatttctt tcaagcaata gaacttcttt
     2521 atttgtgaga gcatcatttt taaatattaa ataatttaat tttcttagaa atatacagta
     2581 aaaatgcaga aagtcccgac atttgtataa attattgttt tgattttcat caataaattt
     2641 aggattcgta aaaaacaata ctatatagat aaaaaaaccg gaaaagaata aagacaaagc
     2701 cccccagtag ttaaaatttt tgaactggta gcatataaaa ttaaacaaaa caaatgaata
     2761 catagtacga ataaatccaa ttatagaggt taaccactgt tcttctaaaa ttgaaatgat
     2821 attgttccaa acattatcat taagaatatc attataacta tcgatattct ctttaactgt
     2881 tgctatcaaa ggaaatagca taaacttcac taaacagaac cccaataaaa aacaaattac
     2941 aatgctcatg aaataagcaa aaaaacgaaa aataccaata ggattaatga tcttgttcct
     3001 tacgtacatc ccgaagagtt tatttgaaat tataaacaga agtattgaaa caaggactaa
     3061 tagtatatag gccaagctac tgctgatcca ttgaaattta tttatataaa ggaaaaatat
     3121 aaaaactgct aaataaaagc cgcattggtt aagagctaac cacaatatct cttctataag
     3181 aagtatatta tgaatagtcc ttgcatttct tggtgccata gtaaatagtg aaaccaaaat
     3241 tggagtatga gttcttcggt aactgattaa accattaaaa aaatgcattc ctataaaaac
     3301 catgattaaa gtacattccc aataaaatga atatttttca ttataaaaat aaataatgag
     3361 tgcaaataaa cctataattg acaaaataat tcgagataaa agagataatg taaaaatgct
     3421 tgtcggtttt aatttattta aaatcggtct atatttacta attaaagaat actgctgctt
     3481 tattcgcaca ttaatcaaaa gtataatgag cctgaaaata gacatatttt ataaccccta
     3541 gttatttaag taatatattg gaaaaggaga caaatacatt gccccctcca ctgtgtaacc
     3601 gacgagaaaa attgaacagt tttcgctaaa taagagtgaa cacttttctg gaaatgttct
     3661 tcaaacattc gttgaagcgc ttgctgtgct tcggcaaatc ctcgcaacgt tcgtcctgcc
     3721 catttctcat taaaatcttg aatggtcaaa tacacgactt tttccgcggc ttctaaactg
     3781 ctcaaacggt tcatcggctt gagacgtttc cgaatctcct tgatcgttcg ttcgatggca
     3841 ttcgtcgtgt aaatcacact tcgaatactg cttggatcat ccataaatgt taggaggaca
     3901 tccaactcgt tggcccaaga ttgaacttct ctcgggtact taccgaacca tttcgactca
     3961 aactgttgaa acatctggaa cgccatctcc ttattcggcg cacgataaat cagtttgaga
     4021 tcctctgcca ctttaaattg atcttttttc cgaacacgat taagagtatt acggacttta
     4081 tgaacgacac aacgctgcac atcggctttc ggatacaccg ccttaaaggc ttcctccagc
     4141 cccggaaggc catcgaagac gccaagaagc acttccttga cgcctctttg gtagagctgt
     4201 tggagaatct cctgccatac ataggcgctt tcttgtcctc ctacgaagaa atcaagaatt
     4261 tcacgatatc cttcttcgtt cacccccagt accacataaa taacttcttt ctccaccgta
     4321 tcccggtgaa gtttcacgta caagccgtcc aaatataaga ccgaataacg tttggatagt
     4381 ggacgatggt gccatttctc gatgtcttct ttcacgacat cggtaatacg gctgatcgtc
     4441 gctggagaat aagcatttcc tagaattcgt tcgataaatt tgccaatttc ccgtatactc
     4501 acgccacttt gatacatccg aatgatggct tcctccagcc agccggtgtg gcgttgataa
     4561 ggggcaaacc tgtgtttgaa attctccgtt tcggtctctt ggcaccaaaa gaccctcaat
     4621 ccggccgtat tgcgtatcta gatttcgctg atcgtagccg tttctcatgt ttggcgttcc
     4681 agcctgttcg atttcgacga aatgtttgat ttcttcccgc atgatcagtt ctcatttttc
     4741 ttttacaaac tgacgaatgg tattttccag ttgatttgcc cagtctacat tcggtatact
     4801 tttagacata ggtagggttc tcctttctct aagatttttg gtccaatcag agaataccct
     4861 accttttttc ttttgttcta gcaaaatgct ttacacaaaa ttgtatacat catttaacac
     4921 actgtacttc catgttgatt accaagcaat aaaagcttgt tttcctctct tttctaactc
     4981 ctctttcaaa tattttttaa tacccatagt accagccgct gctattaggc tcaatccacc
     5041 agtacctaaa gccgtaagaa aagacacaat tgccgttaca gtggtactag catcaagtgc
     5101 cgttagaatc caagcagctg cccatgccgg gactccgaat tcctttgcta aatctgcaac
     5161 tggaaggaaa gttaacataa aaaagtacaa ccctccgatg cttatcccgg caaacaataa
     5221 tataaataat tgagtaagtt tgttttctat tagaatcata gccacatctc cttgcaaaca
     5281 acataaattc cgtttcttaa cttatacgat tacaacctgt aaagtcgatc gacttacaat
     5341 caaaatgtat caagaatctc cgcaaaaaac atccgtattt tccacaattt tgattgcgga
     5401 aaatacctat ttttagagaa aatcatgaca gaagttgtaa tatagtgtaa aattttgatg
     5461 aaccataatc atttattgag gggggctttg tttatgaatc aaaatttatg ggatgtcctt
     5521 caagaacttc ttgagaaaga tggcattgga gcaacggaac ttgcgctcgc aaaggaacgc
     5581 ttaagtccac aagaattctc agcacttgca gcatatcttc aggacagctc aaaaaaagaa
     5641 ggaaatcttt gggtgtaaga ttagatgaac aggattgaaa aaagcactat cagagctttt
     5701 ttacaaaatc acttgttgac tagctgtatg ctagaaaaag aaatcattca atatattttt
     5761 catctgctgc acggcaaggg gaaaatattg agcactaatg aaacacattt ttcctggggg
     5821 gaattttatg cgcaagtatc caccttccat ttaaaagacg acacttgtat acagtctatt
     5881 attagtcatg ctgctgctat tgaacttctc attctagcaa cagacatttt tgatgaaatt
     5941 tccgaccatg accaaagtga tcaagttgta agtcagttaa caactgggga agcagttacg
     6001 atcgctaacg cgcttatgat ggaagcgttt cggcttattc ttcataattc taaagaagat
     6061 atacaagaaa aactttcgat tattatttct gaactacaaa atgcttgcaa tggacaatgg
     6121 aaagacttac attttattat ttctgaatgt attccgacag aagaagacta tttttcgatt
     6181 attaaacaaa aatcatcctc attagtcaaa ttagtttgtg aactcagtga tatgcccaat
     6241 agacatatat gggaaacgat cgcaatggat atcggtatcg ctggccaatt gaaaaatgat
     6301 gctcgggata ttatgtcaga cgacaaaagc gatctcacta ataaaaaagc gacactcccg
     6361 ttcattaaag ccatcgaata tagctctaaa aaagataatg gatggttagt aaggaagctt
     6421 ggccagctaa aagaagctaa taataattct caattaatta aggagattag aaactacatt
     6481 caaaaaacag gggcgatcga ctactgcttg attctctcga aaatttatat ggataaggcg
     6541 tttcgtcaaa tagctactca ttttcccgac aagcagattc aaatagcccg cttaaaaaga
     6601 tatttagaaa gttagggata gaatgaataa aaaagttctt ccttttagcc taatccttat
     6661 ttccattttc gttatttgtt attttttact aaaaatgtac aatgaacatg tttcgccgca
     6721 acgttatttt ccaatattta taggaatgat ctttttattg gctggcattt acagttatgt
     6781 gcaaaaacct aattcgattg tcattcagta ttttttggct cttatgttta ttagtggaat
     6841 ggccctcgcc ctgtcaatcc cttccagcga aaatataaag ccagcaagag aattggaggt
     6901 cgtttttatt tcatttgctc cttacatcct tttaaaattt tttgagcatt ttccttcgtc
     6961 tgcaaaaccg aacttttttc gccaagtgcg cattctcacg ttatatacgg ccatctttat
     7021 aacgatcagt tatctattca ttggtattca tcatcgtgtc atcattagca caatcattcg
     7081 tccatgtatt gtagccaata ttattctagc actgctaggt tgcgtagtcc tattttattt
     7141 acaccttcgt tccaattcga ataagataaa aaatcaaata tatcttttaa ttggcagcat
     7201 cattatatcg tttgcgcccg ttgttattct taacttgatt ccaaatgcgt ttttttccct
     7261 gcccggcgct ccttttcatt atagccttgg cagtatagtc atgtttccac tgacgttgtc
     7321 atatttgtta acccggcagg aaattatcga ttttcgcgaa atattagaga aaatgatggt
     7381 ccgtctattc atgattggtt gttgtttagc aatatttaat ctattattgt cgctatttta
     7441 cgatatacac tttaagctcg gcatcttaat caacacattg ctcatttgcc tttttattgt
     7501 ctatgatcta atcgacaaag ggctcgaacc gctgcaaatg aggaaatggc atggaaaaca
     7561 agaggaaatt caaaaagaaa aactcgccat tcttcaagag ttgctaaacg gaaaacattt
     7621 agaatattgt gctaagctca ttgctgattt aatacacaaa acgatcgatg tgagtggagt
     7681 atgcatcgtg tggaaacatg atcacagccc tactgtattg cataaaacag gaatgttccg
     7741 tcattttcac gatagtgaat tattatctta tgcttgtcaa agcagccatt tttacaaaat
     7801 gactatgaat gaaaagagcg tctttttcta tcctatgaat atagacgatg cattaatcgg
     7861 ctggatgatg attggagaaa aaacaaacgc gacggttttt gacaaagaag aacaaaaact
     7921 aatgaaaaaa atccaaatgg acgccataga attattcgcc agctcaaaaa cgttacaaca
     7981 gattgagaac caactaaaga aaacaataga agaatcatgg atgtccgagc aatcccactg
     8041 gctccttctt catgaacatg aagaagaaaa aaggaaactg tcaattttcc tccatgacga
     8101 ggtactgcaa cacttaattc ttcttctcaa taagcttgaa tggcttattc aaaagaaaaa
     8161 tatagataaa agattgttcg atgacattaa agggctactt caacgtgata tttttgaagt
     8221 cagagagatg tgccatgagc tgtatcctgt tatggtggag gatttagggc ttaaacaaag
     8281 cctctcttca ttaaggcgaa catgcgagat gaactataac gtgattgttg aagtcaatta
     8341 tattgcgaac ctaaaaatca ttccgccgtt tctctcaatc caagcatttc ggatcattaa
     8401 agaattagtt tataacgcca tcaaacattc ttcgtcaaga aagattgttg taactgttga
     8461 agaaacacaa cagtttctaa gtatacaagt caaagattac ggcgtcggat ttaaggtgcc
     8521 ggatcattta ttagaattat cacagacaaa tcacttaggt ttaattacaa ttcaaaaacg
     8581 ggttcatcag ttaaaaggta cactgacaat acattcagag ctgggggctg gaacttgcat
     8641 ttccgtttct ttgccaatta cagttgaaga aggtggggtc aatgaaaatc aaaatattat
     8701 tagtagatga ccatttgttg gtcatgcatg gaattcaaca attgttagaa aatgaaatcg
     8761 atttggaggt cgtcaatacc gtttgtgatc ccgcactttt agagacagaa atcaaaaaac
     8821 ataaccccaa tgtcattgtc atggatataa ggatgaaaaa tgataatggg attgaatgga
     8881 cgagaaaaat tgccaaaaca tatcctacct gcaaagtcgt gattttatcg ggatatggtt
     8941 atgacgaata cattcaagcc gcctatgaag ctggcgctta tgccttcgtc actaaggaaa
     9001 attcggtctt tgaattagcc aatgccattc ggcaaactta tctaggggtt aaatcgttcc
     9061 caattgatcg attggaccgc tacaactgtc ctcttacaaa aactgaatgg aacattctcc
     9121 aactcatttc cgaagataag acaaatgcgg aaattagcga attgctgcat atcagccgca
     9181 gaacggtgga acatcatgtg tcttccattt tgcgaaagct cgaggctgat tcgcgggtcg
     9241 gagcggttgt gaaggcaata aagctaggat tgattgggta g
//
