LOCUS       NZ_CP038996.1          20603 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP038996.1 Enterococcus faecium strain SRR24 chromosome, complete
            genome.
ACCESSION   NZ_CP038996
VERSION     NZ_CP038996.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:16:28
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 401445
            Orig. end    :: 422048
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..20603
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[411445:412048](-)"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10603)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..20603
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..20603
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="1"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             18..2729
                     /locus_tag="ctg1_393"
                     /transl_table=11
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPVM
                     QKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVIQI
                     FSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYTITG
                     FVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTYSKAY
                     KDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTRLEDAK
                     KQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEELNRNAEK
                     IENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTTMTRMVEE
                     NRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFELSNERYDI
                     GSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKPGKRIFLEYI
                     TPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSLSSVSAKQFGP
                     IIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKGHASQSLTVIVP
                     SKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISLYDEDQKEWKVEV
                     KEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEMLSEKLLATDAVTN
                     TSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINISERVRELSTIKVLG
                     FFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMENVIFPLVITWWAYVLS
                     AGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     PFAM_domain     1218..1493
                     /aSDomain="FtsX"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02687.23"
                     /description="FtsX-like permease family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_393_0001"
                     /evalue="6.30E-08"
                     /label="ctg1_393"
                     /locus_tag="ctg1_393"
                     /protein_end="492"
                     /protein_start="400"
                     /score="33.1"
                     /tool="antismash"
                     /translation="RREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLP
                     RIIFELSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKD"
     CDS             3126..4754
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1257:Alpha-glucosidase (Score: 479.3; E-value:
                     2.8e-145)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_394"
                     /sec_met_domain="Alpha-amylase (E-value: 4.9e-93, bitscore:
                     309.5, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDMI
                     WLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVSTE
                     HEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQADLNW
                     RNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPITHTY
                     LKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYENGNKW
                     STPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQGAEMLA
                     TMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKEAFRRIKA
                     KSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSYYKKLIRLR
                     KTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPEGFTEANILI
                     DNYSDTVLHQSLELKPYQAIALLKN"
     aSDomain        3132..4742
                     /aSDomain="TIGR02403"
                     /aSTool="tigrfam"
                     /description="trehalose_treC: alpha,alpha-phosphotrehalase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_394_0001"
                     /evalue="1.50E-256"
                     /identifier="TIGR02403"
                     /label="ctg1_394"
                     /locus_tag="ctg1_394"
                     /protein_end="539"
                     /protein_start="2"
                     /score="850.3"
                     /tool="antismash"
                     /translation="FKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDMIWL
                     NPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVSTEHE
                     WFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQADLNWRN
                     QAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPITHTYLK
                     ELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYENGNKWST
                     PPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQGAEMLATM
                     IHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKEAFRRIKAKS
                     RDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSYYKKLIRLRKT
                     YPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPEGFTEANILIDN
                     YSDTVLHQSLELKPYQAIAL"
     PFAM_domain     3198..4217
                     /aSDomain="Alpha-amylase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00128.26"
                     /description="Alpha amylase, catalytic domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_394_0002"
                     /evalue="1.50E-107"
                     /label="ctg1_394"
                     /locus_tag="ctg1_394"
                     /protein_end="364"
                     /protein_start="24"
                     /score="360.1"
                     /tool="antismash"
                     /translation="GDLKGIKEKLPYLNDLGIDMIWLNPIYPSPQKDNGYDISDYTAID
                     PIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVSTEHEWFKKALAGDQHYQDFFILREEP
                     TDWVSKFGGSAWSPFGDTGKYYLHLYDRTQADLNWRNQAVREELFKVVRFWMEKGVKGF
                     RFDVINVIGKDEQLKNNKENDGKPEYTDKPITHTYLKELNQATFGTDSTIITVGEMSST
                     TIENCILYTEPSREELSMVFNFHHLKVDYENGNKWSTPPFDFAELKRLFHTWGEKMSEG
                     NGWNALFFNNHDQPRALNRFVAIDQYRKQGAEMLATMIHLNRGTPYIYMGEEIGMIDPD
                     "
     CDS             complement(4814..5995)
                     /locus_tag="ctg1_395"
                     /transl_table=11
                     /translation="VKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIFK
                     PVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIWLI
                     PFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFIGNY
                     WESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDFKNLT
                     KIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIGPFIAF
                     FPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVLLVMGDL
                     MGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYFK"
     PFAM_domain     complement(4913..5902)
                     /aSDomain="AI-2E_transport"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01594.18"
                     /description="AI-2E family transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_395_0003"
                     /evalue="1.30E-65"
                     /label="ctg1_395"
                     /locus_tag="ctg1_395"
                     /protein_end="361"
                     /protein_start="31"
                     /score="221.8"
                     /tool="antismash"
                     /translation="LIIYFFHQISFIFKPVGIIIATILPPLLFALILYYLLEPVIKRLS
                     KHLSRNLSVIIVYVIILFLLGLGSIWLIPFLEEQAKTLISSLPDLFQDFQESLRQFLEK
                     TPFADSFNQFFASIDDVTSDIAGFIGNYWESGAQRISNIFSTVTAIFITLFTGPIVAFF
                     LLRDPQKFYQSVLAIVPPAFRTDFKNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLL
                     IGLEFASVLAISAGLLCIIPYIGPFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGD
                     LVIPRVMGDRLQIHPITILIVLLVMGDLMGIVGVIFGIPIYTLVKLLVT"
     CDS             6247..7770
                     /gene_functions="transport (smcogs) SMCOG1252:cation ABC
                     transporter, periplasmic (Score: 247.7; E-value: 2.3e-75)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_396"
                     /transl_table=11
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYDF
                     TKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKTLQ
                     EGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANIRDQ
                     LIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALEYGLN
                     QVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVSLEVLN
                     PLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGYFEDEDV
                     QDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQTDIASIK
                     ISEKEMAFTFKDGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAFRYIQFSDH
                     TIAPADSEHFHLYAGNESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     PFAM_domain     6349..7176
                     /aSDomain="ZnuA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01297.19"
                     /description="Zinc-uptake complex component A periplasmic"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_396_0004"
                     /evalue="5.50E-75"
                     /label="ctg1_396"
                     /locus_tag="ctg1_396"
                     /protein_end="310"
                     /protein_start="34"
                     /score="252.3"
                     /tool="antismash"
                     /translation="VMTTFYPMYDFTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKI
                     QDTDIFVYNDENMETWVPAIQKTLQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGH
                     THELDPHVWLAPSLAIKQVANIRDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETF
                     KQAKQRSFVTQHAAFNYLALEYGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIY
                     FEENAKDSIARTLANEAGVSLEVLNPLEGLTNEQIENGENYLSIMEANLEALKK"
     PFAM_domain     7225..7767
                     /aSDomain="ZinT"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09223.13"
                     /description="ZinT (YodA) periplasmic lipocalin-like
                     zinc-recruitment"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_396_0005"
                     /evalue="1.10E-82"
                     /label="ctg1_396"
                     /locus_tag="ctg1_396"
                     /protein_end="507"
                     /protein_start="326"
                     /score="276.4"
                     /tool="antismash"
                     /translation="EKSVYNGYFEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYK
                     EKLNQDKTAQEYKEYYTKGYQTDIASIKISEKEMAFTFKDGTTKRSNYRYVGKEILTYE
                     AGNRGVRYLFEAEDKESGAFRYIQFSDHTIAPADSEHFHLYAGNESQEVLLKEMENWPT
                     FYPDTMDGREIAQEMLLH"
     CDS             complement(7839..8567)
                     /locus_tag="ctg1_397"
                     /transl_table=11
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEELL
                     NAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILKSN
                     IEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDIQYF
                     STSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKKTREV
                     TLANGETIPASIRGLKKLIS"
     PFAM_domain     complement(7848..8117)
                     /aSDomain="LytTR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04397.17"
                     /description="LytTr DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_397_0007"
                     /evalue="4.00E-20"
                     /label="ctg1_397"
                     /locus_tag="ctg1_397"
                     /protein_end="240"
                     /protein_start="150"
                     /score="72.0"
                     /tool="antismash"
                     /translation="EIKFLPIKDIQYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMH
                     RNFIRCHKSYVINTQNVRSINKKTREVTLANGETIPASIRGLKKL"
     PFAM_domain     complement(8199..8558)
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_397_0006"
                     /evalue="1.30E-12"
                     /label="ctg1_397"
                     /locus_tag="ctg1_397"
                     /protein_end="123"
                     /protein_start="3"
                     /score="48.0"
                     /tool="antismash"
                     /translation="IYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEELLNAA
                     KIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILKSNIEP
                     TDYIVKEDLYDLKENV"
     CDS             complement(8580..9860)
                     /locus_tag="ctg1_398"
                     /transl_table=11
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWVY
                     SILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKSSV
                     IEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYIIIFY
                     TRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDYIKDL
                     EKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPANLSMLD
                     NMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDNAIEGAS
                     AAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLGLFILDEL
                     TKTNPYLFLETSIENQRFSQTIYIQIK"
     PFAM_domain     complement(8589..8900)
                     /aSDomain="HATPase_c_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14501.8"
                     /description="GHKL domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_398_0008"
                     /evalue="5.00E-20"
                     /label="ctg1_398"
                     /locus_tag="ctg1_398"
                     /protein_end="424"
                     /protein_start="320"
                     /score="71.4"
                     /tool="antismash"
                     /translation="TVNLVRMLGIILDNAIEGASAAKKKKIELTILKKNHSVMIRVINT
                     TTNTLPLNQLKQKGFSTKTNPKNEGLGLFILDELTKTNPYLFLETSIENQRFSQTIYIQ
                     "
     CDS             complement(9910..10020)
                     /locus_tag="ctg1_399"
                     /transl_table=11
                     /translation="MKKTIIKQLTNLSDFFVSGCCFGMSSEFKIPEKLKK"
     CDS             complement(10001..10603)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_400"
                     /sec_met_domain="AgrB (E-value: 7.6e-29, bitscore: 97.7,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFALEVLLNNLGKLAVV
                     LVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQLT
                     ISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFFSAS
                     YFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     PFAM_domain     complement(10067..10594)
                     /aSDomain="AgrB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04647.17"
                     /description="Accessory gene regulator B"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_400_0009"
                     /evalue="6.00E-28"
                     /label="ctg1_400"
                     /locus_tag="ctg1_400"
                     /protein_end="179"
                     /protein_start="3"
                     /score="97.5"
                     /tool="antismash"
                     /translation="KVVNKLLEALFSGDKSEEDMVYVQVKFALEVLLNNLGKLAVVLVF
                     SLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQLTISF
                     PMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFFSASYFS
                     TYLLLGIVLEIAT"
     CDS             10847..11053
                     /locus_tag="ctg1_401"
                     /transl_table=11
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCAV
                     EDNDTAHNLHWQLVVRKSSTIEE"
     CDS             11377..12084
                     /locus_tag="ctg1_402"
                     /transl_table=11
                     /translation="VIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPLFYSNP
                     EKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEVEVKQYE
                     GLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPELYSYYKEL
                     NRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEADAQSIRYT
                     TNNPKAKGIFTTK"
     PFAM_domain     11380..11988
                     /aSDomain="dNK"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01712.21"
                     /description="Deoxynucleoside kinase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_402_0010"
                     /evalue="1.10E-56"
                     /label="ctg1_402"
                     /locus_tag="ctg1_402"
                     /protein_end="204"
                     /protein_start="1"
                     /score="192.0"
                     /tool="antismash"
                     /translation="IIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPLFYSNPE
                     KYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEVEVKQYEG
                     LLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPELYSYYKELN
                     RRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIK"
     CDS             complement(12165..12848)
                     /locus_tag="ctg1_403"
                     /transl_table=11
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILSI
                     IQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFFVS
                     LTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCISKEK
                     ADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQFYHT
                     NRFTI"
     PFAM_domain     complement(12219..12815)
                     /aSDomain="DUF1275"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06912.13"
                     /description="Protein of unknown function (DUF1275)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_403_0011"
                     /evalue="4.30E-36"
                     /label="ctg1_403"
                     /locus_tag="ctg1_403"
                     /protein_end="210"
                     /protein_start="11"
                     /score="124.7"
                     /tool="antismash"
                     /translation="GLLLTFIGGAMDSYTYIQYGAFASAQTGNIILSIIQAFDGEWLSV
                     GKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFFVSLTPVHEHPALV
                     TILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCISKEKADFDRFFHYLS
                     VVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMAL"
     CDS             13066..14202
                     /locus_tag="ctg1_404"
                     /transl_table=11
                     /translation="LNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEAP
                     GLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKTQT
                     ICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFFRIY
                     NEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRLDYWQ
                     NMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDVLQNLK
                     SALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDDQSIYGF
                     RGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGAID"
     PFAM_domain     13291..14130
                     /aSDomain="UvrD-helicase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00580.23"
                     /description="UvrD/REP helicase N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_404_0012"
                     /evalue="2.00E-51"
                     /label="ctg1_404"
                     /locus_tag="ctg1_404"
                     /protein_end="355"
                     /protein_start="75"
                     /score="175.5"
                     /tool="antismash"
                     /translation="NQEQKAAITYDMKKHLRIIAGAGSGKTQTICAKAVYLMTQKQVDE
                     ERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFFRIYNEICRKFPEVAMQGIQ
                     GDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRLDYWQNMNLSVEEMVQLVKEK
                     YDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDVLQNLKSALENEEIQHYIGQKY
                     DYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDDQSIYGFRGSEPAYIKNFEKEY"
     CDS             14199..15251
                     /locus_tag="ctg1_405"
                     /transl_table=11
                     /translation="LISYNKNDRIPKAMIPAQKEAGVMEAYLFSDTKAESQWLIKQIQT
                     FIQKNGKYKESIILYRSASQTQQLVQSLLKTNIPFVLEADSPYEGIFGIKSFQHFYQKI
                     VHWQTALNLQKKNQAYQQLLRQLMADCYLKKSECDQYFSPKYQNIAVADYILSISPNLK
                     SKSAEIREFEEALRKTDQHQEIYSLVQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRR
                     LQALSQETQATAKELKTRLIAYRQGKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYN
                     GATEKKVIDFNEIKAEPVTTIEEERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIK
                     ETGSRVKKGK"
     PFAM_domain     14238..14441
                     /aSDomain="UvrD_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13361.8"
                     /description="UvrD-like helicase C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_405_0013"
                     /evalue="4.10E-06"
                     /label="ctg1_405"
                     /locus_tag="ctg1_405"
                     /protein_end="81"
                     /protein_start="13"
                     /score="26.6"
                     /tool="antismash"
                     /translation="MIPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESII
                     LYRSASQTQQLVQSLLKTNIPFV"
     PFAM_domain     14547..15167
                     /aSDomain="UvrD_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13361.8"
                     /description="UvrD-like helicase C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_405_0014"
                     /evalue="9.20E-21"
                     /label="ctg1_405"
                     /locus_tag="ctg1_405"
                     /protein_end="323"
                     /protein_start="116"
                     /score="74.8"
                     /tool="antismash"
                     /translation="NQAYQQLLRQLMADCYLKKSECDQYFSPKYQNIAVADYILSISPN
                     LKSKSAEIREFEEALRKTDQHQEIYSLVQSYLHLPRIAKEIDQSDQEWIREEVKQHATF
                     RRLQALSQETQATAKELKTRLIAYRQGKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLP
                     YNGATEKKVIDFNEIKAEPVTTIEEERRLFYVAMTRARNRLYLC"
     CDS             15620..16234
                     /locus_tag="ctg1_406"
                     /transl_table=11
                     /translation="MTYTHLTTDELVIIESYFKMNQSVAKTAHCLNRSRQTIHKVYLFF
                     KQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPISCS
                     ARTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEFGHL
                     EGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKN"
     CDS             16662..17072
                     /locus_tag="ctg1_407"
                     /transl_table=11
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKKI
                     LAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRILIG
                     FNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     aSDomain        16665..17003
                     /aSDomain="TIGR01617"
                     /aSTool="tigrfam"
                     /description="arsC_related: transcriptional regulator,
                     Spx/MgsR family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_407_0002"
                     /evalue="1.80E-37"
                     /identifier="TIGR01617"
                     /label="ctg1_407"
                     /locus_tag="ctg1_407"
                     /protein_end="114"
                     /protein_start="1"
                     /score="126.2"
                     /tool="antismash"
                     /translation="IKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKKIL
                     AATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRILIGF
                     NEDEIRSFV"
     PFAM_domain     16674..17000
                     /aSDomain="ArsC"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03960.17"
                     /description="ArsC family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_407_0015"
                     /evalue="6.80E-22"
                     /label="ctg1_407"
                     /locus_tag="ctg1_407"
                     /protein_end="113"
                     /protein_start="4"
                     /score="77.5"
                     /tool="antismash"
                     /translation="YTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKKILAAT
                     EGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRILIGFNED
                     EIRSF"
     CDS             17086..17442
                     /locus_tag="ctg1_408"
                     /transl_table=11
                     /translation="VEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAEE
                     LCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVLFI
                     GYNEQLMEQLILNK"
     PFAM_domain     17101..17418
                     /aSDomain="ArsC"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03960.17"
                     /description="ArsC family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_408_0016"
                     /evalue="1.70E-07"
                     /label="ctg1_408"
                     /locus_tag="ctg1_408"
                     /protein_end="111"
                     /protein_start="5"
                     /score="31.4"
                     /tool="antismash"
                     /translation="YGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAEELCSFE
                     EVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVLFIGYNEQ
                     LM"
ORIGIN
        1 tatggtaggg ggattttatg aaaacaagaa catatcttaa agcaggtttt cgcgaaattc
       61 ggcaatctaa aggacgattc attgcaatca tccttattgt catgctagga acacttttat
      121 ttgtaggtgt caaaactgct ggacctgtca tgcaaaaaac gatggatcac tatgttggta
      181 cagcaggact ttctgatttg caaatcgttt ctactggtgg cttgacacaa aaagatattg
      241 ctcaagcaga aaagatccca gatgcaaaag tagaaacagg aaaacagatc tattattcca
      301 atactggcaa aaacgaagtg attcaaatat tttcttataa caaaaataac aagcagaaca
      361 agctacaatt aactgatgga aaactcccgg aaaaaccaaa ccagcttgta ttggatgaaa
      421 aagcggaaga tgaagggtat aaaatcggtg atatttatca gattgattca gatgaattga
      481 aagaaaaaga gtataccatc acgggctttg tccgttctcc attgttcatc aacaatttgg
      541 agagaggata cgcgaacgtc ggaaatggta gcgtcgatta ttttgtctat ttacctgaat
      601 ccgtttttaa aacagatatt tattctgtct tatatcttga ttttacaaac gtaaagaatt
      661 tgaatacgta cagcaaagct tacaaagata aaatggagca aaatcaagaa aaggcagaaa
      721 agtatttaca agatcgaccc gaagaacgct tagaagagct gaaaaaatcg gccaacgaag
      781 aattagaacc ggcacagcaa aaaatagcgg atggcaaagc acaaacaacg caagcaagaa
      841 cacggttaga agatgctaaa aaacagttag cgcaacagtc agcaactatc cagcagcttc
      901 ctgaagcgca acgaacaatc gctgttcaaa cattatctca acaagaagct caacttgctg
      961 aacaagaaag gcaattagtt gagaaagaac gtgaactggc ctctgcagag gaagaattga
     1021 atcgaaatgc agaaaaaatt gaaaatttaa ctaaaccatc atacctatac aatgaacgtt
     1081 cagaaaatgt cggttttcaa gaatttggtg atctgtctga tcgtatcgct gcgattgcca
     1141 atgtttttcc tgttttcttt ttctttattg ccgcattgat cacctttacg acaatgacac
     1201 gtatggtaga agaaaaccgc agggaaatcg ggacattaaa ggcgttaggt tatacgaaag
     1261 ttgaaatcgc aaaaaaatat gcaatctatg caagtctagc ctcagggata ggtattgttt
     1321 taggaacgat attaggaacg aatcttttgc caaggatcat ttttgagctg tctaacgagc
     1381 ggtatgatat tgggagtgcg cttatttttt atgactggcc gccgatttta caagcagctg
     1441 ccgcattctt cattgccgca tttggcgctg caatgatcgt tttattcaaa gatttaagag
     1501 aacggcctgc tgcattgctt caaccgaaag caccgaagcc agggaaacgc atttttcttg
     1561 aatacatcac tccgctgtgg tcacgcctta gctttaatca aaaaatcagt taccgaaatc
     1621 tcttccgata taagtcaaga atgcttatgg cgattatcgg aattgctgga tgtgccgggc
     1681 tgatggttgc aggcgtggga ttgaaagatt ctctaagttc tgtttcagcc aaacaatttg
     1741 gaccgatcat tgactatcaa gcaatcgtta cattggattc atccacggaa gatagtcgtc
     1801 aaaaagcagc ggatatgctg cagaagcaag aaaaagtaaa tgagatccta gctattcata
     1861 ctcaaaccgt agaattgaga aaaaaaggac atgcttcgca aagtctgaca gtgatcgtac
     1921 caagtaaaac agctgatttg gatcgtttta tccatttaac tgatcttgaa gagaacccac
     1981 gctccttgcc taaaacagga atcgctatta cgcaaaaagt agcagaacta tttgacttat
     2041 ctacaggaga tcatatttcg ctttatgatg aagatcaaaa agaatggaaa gtcgaagtaa
     2101 aagaaatcgt gaaaaactat ctaggtagct ttatttatat gtcccctgaa tattatgctt
     2161 cagttactga tcaatcgatg atggataatg catttttgct gcgtacagat aagatgacaa
     2221 caaaagaaga agaaatgctt tccgagaaac tgcttgccac agacgctgtg acaaatacgt
     2281 ctttcatgtc caaacaaatc gaaacgcaag aagaatcaat ggcgaactta gactcggttg
     2341 tcttaatctt tgtcgtatta tcaggactgc tggcttttat cgtcttgtat aatctaacta
     2401 atatcaatat ttccgagcgt gtacgcgaat tatctacaat aaaagtcctt ggattttttg
     2461 ataaagaagt cacgatgtac attgttcgag aaaatatcat ctttactctt ttaggaatca
     2521 tcggaggatt tggtgtagga tatatattga ctgacttcat cttgcaacaa gcgtctatgg
     2581 agaatgtcat ctttccatta gtgatcacat ggtgggctta tgtcttatca gcaggattaa
     2641 ctatcgtatt tacggttatt gtgatgattg ttacccattt caaattaaag catatcgata
     2701 tgattgatgc gttgaaatcg aatgaataaa aacagaggtt gtgaaatcag cgttttgagc
     2761 taataacgag ggtcagctgc taattgaaca ccatgaatca gaggttgtaa aaaagccgtc
     2821 ctgcatcgag caaaaagaat actcaaataa aattagctcc tcatgtttta catttgagaa
     2881 gactgattgc cgtagataaa agcttttgaa caccatttat agaagaaaca agaatatttt
     2941 gctattttaa acaagaggat agacaaatac atgtctgatc tcttgttttt tattgggcaa
     3001 cagacctctt agaatgtata aagataaatt ttacaaacgc tttcggttca gttataataa
     3061 taaatgataa cttgtatata taagttgtgg taggtaataa atcagttgaa tggaggtaaa
     3121 tatccatgac atttaaagac aaagtcattt accaaatcta tcccaaatct tacaaagaca
     3181 gtaatggtga tggaattgga gatttaaaag gaatcaaaga aaaactcccg tatctgaatg
     3241 atctaggcat cgacatgatt tggctaaacc ctatttatcc aagccctcaa aaagacaacg
     3301 gttatgatat ctctgattac acagccatcg atcctatctt tggtacgatg gaggaattcg
     3361 aacagctaat agccgaagca aagaaatacc ggatagaaat catgctcgat atggtgctga
     3421 atcacgtttc gacagaacat gaatggttca aaaaagcact agcaggggac cagcattatc
     3481 aggacttctt cattttaaga gaagagccaa cggattgggt atcaaaattt ggtggaagtg
     3541 cttggtcgcc atttggagat acggggaaat attatttgca cttatatgat cggacacaag
     3601 ctgacttgaa ctggcggaac caagcagtaa gagaggaact attcaaagtt gttcgttttt
     3661 ggatggaaaa aggggtaaaa ggattccgtt tcgatgttat caatgttatc ggtaaagacg
     3721 aacaattgaa aaataataaa gaaaatgatg gcaaacctga atatacggac aaaccaatca
     3781 cccatacgta tctaaaagaa ttgaaccaag caacgtttgg gacggattcc actatcatca
     3841 cagtcggtga aatgagctct acgacgatcg aaaattgtat cttgtataca gaacctagta
     3901 gagaagaatt atcaatggtc tttaatttcc atcatttgaa agtcgattat gaaaatggga
     3961 ataaatggtc tactcctcca tttgattttg cagaattaaa gcgactattt catacatggg
     4021 gagaaaagat gagtgagggt aacggctgga atgctctatt ttttaataat catgatcagc
     4081 cacgtgcgct caatcgattt gtagctatcg atcagtatcg aaaacaagga gcagagatgc
     4141 tagcaaccat gatccatttg aaccgtggga cgccctatat ttatatggga gaagaaatcg
     4201 gcatgatcga cccagactat tcatcgattt ccgactatat tgacgtagaa agtttgaatg
     4261 cttataagtt actccttgaa caaggattca cagaaaaaga agcgtttcgt cggatcaaag
     4321 caaaatctcg cgataactct cgaacaccca tgcaatggtc agacacagaa caagcaggat
     4381 ttactacagg gaaaccttgg ttaaaagttg gaggcaagct agaagagatt aatgtagaaa
     4441 aagaactatc ttctgaagat tctattttgt cctattacaa gaaattgatt cggctgagaa
     4501 aaacatatcc aatcgttgca caaggagatt atcatgctta tgaagcaaat catccggaag
     4561 tttatggctt tcttcgccaa tttgaaggac agcagctgct tgtattaaca aatttctatg
     4621 ataaagatac aaggatcgcc atcccagaag gattcacaga agccaatatt cttatcgata
     4681 attattccga tactgttctt catcaaagtc tggagctaaa accataccag gcaattgctt
     4741 tgctgaaaaa ttaaaacaaa aacacaaaac gtcgttccta cgagctattc tcgtaagatc
     4801 gacgttttgt gttttattta aaataatctt cttcagaaaa tgaagagttt tcatactctc
     4861 ctttatcgcc ataaaattta ttgtagcgtt gtttgaattt acggaaaata aaagtaacga
     4921 gtaatttgac taacgtatag ataggaatac caaaaataac gcccacaatt cccattagat
     4981 cacccatgac aagtaaaacg attaagatcg taatcggatg gatctgtaaa cgatcaccca
     5041 ttactcgagg aatcaccaag tcaccgtgga gaagttgtac ggcaaaccag acaatgacaa
     5101 atttgacagc cataaaagta gagtcttgga atgcaatgat caaacctgga aagaaggcga
     5161 taaacggccc aatatatgga atgatacata acaacccagc agaaatagct aaaacactag
     5221 caaattctaa tccgatcagt aagaaacaaa cccagtagac tgctccaagg ataaatgaag
     5281 caatgatttg cccctttaga aatgaaccca attgttgatt agcaatcttt gtcaaatttt
     5341 taaaatctgt acgaaatgct ggtgggacaa tcgctaaaac tgactgataa aatttttgag
     5401 gatctctcaa aaggaaaaaa gcgacaattg gaccagtaaa taaagtaata aaaatagctg
     5461 taacagttga aaaaatgttg ctgatccgtt gtgcgccact ttcccaataa tttccaataa
     5521 atccagctat atcagacgtc acgtcgtcaa tagaagcgaa aaattgatta aatgaatcgg
     5581 caaaaggtgt tttctccaaa aattgtcgga gactctcttg aaaatcttga aacaaatctg
     5641 gcaaactact gatcaatgtc tttgcctgtt cttcaagaaa aggaataagc catatgcttc
     5701 caagccccaa taaaaataaa ataatcacat aaacgataat gactgacaag ttcctcgaaa
     5761 ggtgcttgct caaacgtttg atgactggtt ccaaaagata atacaagatc agtgcaaaca
     5821 ataatggggg caagatagta gcgataatga ttccgacagg cttgaatata aacgagatct
     5881 gatggaaaaa ataaatgatc agcgcaagta agataactat tcctaaaaca tagtaagagg
     5941 tttttcctcc taaaaagcgg atcaaacgat tcgttgtatc tgtttctttt ttcactcttt
     6001 ttcctccttt atctataact tcattataga caaaagcggg tataaaagga aaatgataga
     6061 ggttgattgc aaaaatatcg tcaatcattc atataaactt tctcatcaat taaaataaga
     6121 aaacgcttga cagttctttt aaccatatga taaattaaat cctgttgcta aaacgtaact
     6181 attacggttt gcgaaaagcg aatcggaaca ttcaaatgaa agaagatgag aagaggagtg
     6241 tcataaatga aacgattgat aggtatattg gccatgctgg ttttagcagg tatgttaact
     6301 gcttgcgggg caagtgggaa agccgaggac agtaaagaaa aattgagcgt gatgacgacc
     6361 ttttatccca tgtatgattt tacaaaagca atcgtcgggg atgaaggaga agtagagtta
     6421 ttgattccag cagggactga ttcccacgat tatgaacctt ctgctaaaga catggcaaag
     6481 atccaagata cagatatctt tgtttataat gatgaaaaca tggaaacatg ggtccccgca
     6541 atccaaaaaa cattacaaga aggcaatgtc catacgataa aagcgacaga aggtatgctt
     6601 ttacttccgg gaagtgaaga aggacatgat catgaccatg aacacgggga agaaggccat
     6661 acacatgagc tagacccaca tgtatggcta gctccaagtt tagcaatcaa gcaggtagca
     6721 aacatacgtg atcagctgat tgaagcttac ccagaaaaac aggaagtatg gacaaaaaat
     6781 gcagcagcct ataccgagaa acttcaagca ctccatcagc tttatcaaga aacctttaag
     6841 caagcaaaac aaagatcttt tgtcacgcaa catgctgcat tcaactatct agcgttagaa
     6901 tatggattga atcaagtatc gattgctggt ctttcttcta gtgaagaacc gtctgcggcg
     6961 agaattgctg aactgaaaca ctttgttaaa gaacatggaa tcaactatat ttattttgaa
     7021 gaaaacgcca aagatagtat tgccagaacg ttagcaaacg aagcaggtgt atctttagaa
     7081 gtattgaatc ctttggaagg attgacgaat gaacaaatag aaaatggaga aaactatctt
     7141 tctatcatgg aagcaaacct cgaagcgttg aaaaaaacga cagagacaga aaacccgcta
     7201 gaagatactt tgacccccaa aaaagaaaag agcgtctaca acggttattt tgaagacgag
     7261 gatgtacaag atcgctctct ttcagattgg gcaggaactt ggcaaacagt agatacgtat
     7321 gtagaagatg ggacttttga tcctgttttt gaatataaag aaaaattgaa tcaggataag
     7381 acagcacaag aatataaaga atattatacg aagggctatc aaacagatat tgcttcaatc
     7441 aagatcagtg agaaagagat ggcatttacg tttaaggatg gaacaacgaa acgttcaaat
     7501 tatcgttatg tagggaaaga aatcttgacc tacgaggcag gaaaccgtgg cgtaaggtat
     7561 ctattcgaag cagaagataa ggaaagtggc gcttttagat atattcaatt cagtgatcac
     7621 acgattgcac cggctgactc cgaacatttt catttatatg caggaaatga aagtcaagaa
     7681 gtattgctga aagaaatgga gaattggcca acattttatc cagatacaat ggatggacgt
     7741 gaaattgcac aggaaatgct tttgcactga taggcaaaaa agaaccgaag ggtttggatc
     7801 ggctggtcat ttagtcggtc caaactattc ggttcttttt atgaaatcaa tttctttaat
     7861 ccacggatag aggctgggat ggtctcgccg tttgccaacg tgacttctct ggttttttta
     7921 ttaatcgacc gcacattttg tgtattgata acataggatt tatgacaacg gataaaattc
     7981 cgatgcattt tctcgatttc tttgatcttc tcatagaatt gtaattgggc atgagtcaaa
     8041 tggacttcca gtttatgtgg cgctcctagc gaagtagaaa aatattggat gtctttgatc
     8101 ggtaaaaatt tgatctcatc attaaactct attttgaaga tatctttttg gatttgggac
     8161 atttgaaaat cttcgaaaat tttgctcagg atatgctcga cattttcttt taaatcataa
     8221 agatcttctt tgacgatata atcagtcggt tcgatgttgc tttttaagat tttcatcgac
     8281 atttccgtat gggaagtcac atagattatt tttcctaaag gatctaattc acggatcaat
     8341 ttaccgatcg ctacaccatc catttcactg tcttctagtt cgatatctaa aaagtaaata
     8401 ccaaaagaag aagttctgat cttggctgca ttgagaagtt cttccggatc agaggtagaa
     8461 atatggacat aactgtctaa gttttcaatc atgattctat ttttgatcac cgttgataaa
     8521 acttctaatt gttttggatc gtcttcacaa atataaatgg gaatcatatc attactcctt
     8581 tattttattt gtatataaat cgtttgagaa aaacgctggt tttcaattga tgtttcaagg
     8641 aaaagataag gattggtctt tgtcaattca tccaagataa acaagccaag gccttcgttt
     8701 tttggatttg tttttgttga gaaccctttt tgtttcaact ggtttaacgg taatgtattt
     8761 gttgttgtat tgatcacacg aatcatcacg gaatgattct tcttgagtat ggtcaattcg
     8821 atttttttct tctttgcagc actagctcct tcaatcgcat tgtccaagat aataccaagc
     8881 atacgtacaa ggtttaccgt atgtttcgta tccagttcga ttggctcagg aaaatgaagc
     8941 tggacgatca accctttttc ctgtgccatc atgagtttta atgacagtaa actacggatc
     9001 tcaggaactt tcatattatc caacatactt agattggccg gaaaaaggtt catcatctgg
     9061 cgtgtaggta atatcgtttg atcataataa gaccgtaatc cttctaagtc gccttctgaa
     9121 atatagctgt gaagagaaaa aagcagattt tggtaatcat gtttgaattc tctcaagtct
     9181 tgatagtttt tttctagatc tttgatataa tcctgttgca tcctgacttg ttgctctaat
     9241 aactgatcag ctaatttctt attagagatt ttccaataat aaaccaagat gatcaggcca
     9301 acacacagat atagaatgaa aaaactcgta ttcaaagcta agacatcagg tgtttcacca
     9361 gaaaaacggg tataaaaaat aatgatatag tatgtaaata atatcaatgt cccgatcgta
     9421 ccgatcatac ggcggtccac agtgtgaaac caagtctcta acgatttttt taaacaaaaa
     9481 gctaataaag cagataaaaa agcggataag acaatgtgaa aatactgcaa tgaatctcct
     9541 ggttcaataa ccgaagattt caaaacaaaa aaatcgccga tgcttgttaa gtgatctcct
     9601 aaaagcgacg tcaataaccc aaaaggaagc gcgtaaacca attgttgacg cgaagtcgaa
     9661 aagaagaaaa aagtaagcat cagcattcct atagcaatta gagcagtaaa aatccctaaa
     9721 atcgaataga cccatccaat caaaatacaa gaaatcagaa tgactcccgc aaacagatat
     9781 ttgtatcgga tgtgatggtc aatcaataag atacaaattg tgtaaatcaa atattgcaac
     9841 gctatggacc ataaaaacat aaagtacagc tcccattgat ttttaccaaa ttatagcaca
     9901 attagcgtat tattttttta atttttcagg gattttgaat tcagaactca taccaaagca
     9961 gcagccagat acaaaaaagt cagataagtt agttaattgt ttaatgattg tttttttcat
    10021 gaaagattcc tccaaaattc atcaagtagt ttgtaatagg aagcaacgta gctatttcta
    10081 aaacaatccc aagtagcaaa taggtagaaa agtaagaagc tgagaaaaat aaagtaatga
    10141 gagaaaaaat tagaaacatg ctgatcgcct tctttaataa tgggggacgt ttctcgggtt
    10201 caatgggatt gattgctgta cctcttgatc catagcgaag cagtaacaaa aagcagctga
    10261 ttaacaaaaa gaccatcatt gggaaggaga tagtcaattg cagatgtttc atcaccaagg
    10321 gaacgcccca taaataaagt agtgtccaca gcagacaaac gaattcagag tcggaatgca
    10381 atccataagc atatctgcgg atgcagatat aagaaagaaa ggtgattcct gtttccgccc
    10441 atgagcctgt caccagagaa aagactagaa cgaccgctag ttttccaaga ttattcaata
    10501 aaacttctaa ggcaaatttt acttggacat acaccatatc ttcttccgat ttgtctccgc
    10561 tgaataaggc ttctaataat ttgttcacaa ctttatcttt catctcatac gtacctccac
    10621 cacaaatttt atgctaaaaa aataaaaaac gtcttttgtt tcataaaaag tggttttgac
    10681 atcaaaaccg tcatgatctc ctaaaaaaat cttcgttttc caagaacctt accaaaaaaa
    10741 gtgacagttt tgatacgaaa agtacttttt atgacaagtt tgtgcttttt cgagtgattt
    10801 atgttaaaaa attactgacc ttataaaagg tgatggaggg attcttatgg aaaatgaaca
    10861 attgtttgaa gtcggcgaaa catatgcatt taaatctgat ttatttgaat caccaataaa
    10921 aggaaaaata gaaaaaatct atgaaaatag tgtgatgata cgtgtcatga aatgcgcagt
    10981 agaagacaat gataccgctc ataatctgca ctggcagtta gttgtacgca aatcaagtac
    11041 aatagaagaa taaaaacaga taaaatgttg agagcataaa gaggttgtga gtctcccgtt
    11101 tagctctgag ttacaaggaa taatgttaaa aaacagcttt tcatgtttta tgaatattgc
    11161 cttgtgaccg aggtgttggc aggagaatac tgtttatttg aaaaaagggc tgcgacaaga
    11221 cttttgtcac agcctttatt ttcatgaata ggagttactt ttggctactt ttagagaagt
    11281 agcttttaag gagcagataa agtcaaggct tttatttcta taaatgaagt agtaaaatga
    11341 agaacagatt ttattacagg aaggatgccg ataattgtga tcattgttgc aggaacgatc
    11401 ggtgcaggga aaagcacact aactgaaatg cttgcccaag atttagaaac aaaacctttt
    11461 tatgagaacg tggaagataa tgaagtattg ccgctatttt attctaatcc agaaaagtat
    11521 acttttttat tacagatttt ctttttgaac aaacgctttt tggcaatcaa agatgctttc
    11581 agccatgatg acaacgtact agaccgctcc atctacgaag atagtatgct gtttcatttg
    11641 aatgcagatt tagggcgtgt ttctgaagta gaagtaaagc agtatgaagg tcttttagaa
    11701 acgatgctga aggagttaga agaaatttcg ccacaaaaga aaccagatct actggtttat
    11761 attcgtgtat cctttgaaac tatgttagcg agaatcaaaa aaagaggccg ggaatatgaa
    11821 cagctagaac aagatcctga actctattcc tactataaag aactcaatcg acgatacgaa
    11881 gagtggtatg aacagtttga tatatgtccc aaaatagtga tcgatgggga caaatatgat
    11941 ttcgtagccg atccggcatg tggagaacaa atcgtacaag aaatcaagat gcgggcaaag
    12001 aaaatgacag aagaggcaga tgcccagtcg atccgctaca ctacaaataa cccgaaagca
    12061 aagggaatct ttacaactaa ataatataaa aactaagcaa attgctcact cgcagatatt
    12121 tctctgtgag cagcatcttg cttagttttt ttgattcatt gagatcaaat agtgaaccga
    12181 ttcgtatgat aaaattgcca taaatgaaat gtctgagtga gggccatgat caaaaataaa
    12241 atggaaacga tcaaaatcga atgggcgcca aacagatgat gacagaaaac aaggacaata
    12301 gctcctgcga taaaggcaag aacgacactt agatagtgga aaaatcgatc aaaatctgct
    12361 ttttctttag aaatacaata atcatataag ttcgttgcta ccccttttaa atttccagtt
    12421 gtaaataaat tagtgtaggc acgcccgttg attttatcaa aagctaccca ctggatcgat
    12481 gcagtaaaag caatcaaaat cgttactaat gcgggatgct catggacggg tgtcaaacta
    12541 acaaagaaaa aaatcactgc ttcataatat agaacaaaca agcgccagaa atgtttttct
    12601 ttttttctaa aataatcaat tagatacttt gttagaagaa tccctaagaa aaagaaaagg
    12661 gtagacaata cttttttacc aacacttagc cattctccgt caaatgcttg gatgatcgat
    12721 agaatgatat tgccagtttg agcagaggca aaagcaccat attggatata agtataactg
    12781 tccatggctc ctccgataaa tgtcagcaaa agtcctattg tacgcccctc gtgaaaggaa
    12841 gtctgcattt ttttcatcac cttttatgaa tatttttgtc ttccttatct tagcataaac
    12901 gattgaaaaa aaggaaaaat tttcagaaaa ctaaaatcat atcgcttccc attttcattt
    12961 ttagaaaggt ctgttagtat aaagaaaaaa tagacaacga aactttaaat aaccaacttg
    13021 aaataaacaa attcaaagaa gaaagatggg aaggaaatca atcagttgaa tgaaaaagaa
    13081 attctccgat tacaaaaaga attgaaacgc tgggagaaca agtataaaaa gcttcaacaa
    13141 gtctttcggc tacaagaaga aatcattgct acctatgaag cggcttatgg cgaagcaccc
    13201 ggacttattg aggaagaagt acaagtaaaa gaaagtgaag gaaacagctc tttctttaaa
    13261 atgatggaga aacgttccta taatcgcttc aatcaagaac aaaaagcagc tatcacatat
    13321 gatatgaaga aacatcttcg aatcatagca ggagctggga gcggcaaaac gcaaacaatc
    13381 tgtgcaaaag ctgtttatct gatgacgcaa aaacaagtag acgaagaacg catactaatg
    13441 atcactttta caaggaacgc tgcaaatgaa ctaaaaaaac gagtagataa tttcagccag
    13501 agaaaaaccg ctgtccatat cggaacattc catagtatct tttttaggat atacaatgaa
    13561 atttgtcgaa aatttcctga agtagcaatg caaggaatac aaggagactt ttcaaaggat
    13621 actgcacaaa aagtgaatgc tgttttgcaa cagctgatac gtaaatataa tctttatata
    13681 tttgatcaat atggagaaaa aacgattgct tctcggttag actattggca gaatatgaac
    13741 ctttcagtag aagaaatggt tcagttagtt aaagaaaaat atgattccat tgataagaat
    13801 gcacgacagc cgatatcaga acgactgtat ggattgctca cggaactcca agaacaaaaa
    13861 agaagccagc aattgctaga gttcaatgat gtactccaaa atctgaaaag cgctttggag
    13921 aatgaggaga tccagcatta tatcggccaa aaatatgatt atctattcat tgatgaattt
    13981 caagatacta atccacttca atgggaaatc gtgaaacgga tgacaaagga aaacaggatc
    14041 aagttgattg ttgttggaga tgatgatcag agtatctatg gattcagagg atcagagcca
    14101 gcatacatca agaactttga aaaagaatat cctaccaaaa ctcttttctt attaactaat
    14161 tatcgttctc gggcagctat tgtccaagga gcaatagatt gatcagctat aataaaaatg
    14221 atcggatacc aaaggcgatg attccagcac aaaaagaagc aggtgttatg gaagcctatt
    14281 tgttttctga tactaaagca gaaagtcagt ggctaatcaa acaaattcag acatttattc
    14341 aaaaaaatgg gaaatataag gaatcaatca tattataccg atcagcttca caaacgcagc
    14401 agcttgtcca atctctgctg aaaacgaata ttccttttgt actggaagca gatagtccat
    14461 atgaaggtat ctttggtatc aagtctttcc aacatttcta tcaaaaaatt gttcattggc
    14521 aaacagcact gaatctgcaa aagaaaaatc aggcctacca gcaattgctc cggcagctga
    14581 tggcagactg ctacctgaaa aaaagtgaat gcgatcaata cttttctcct aaatatcaaa
    14641 atatagccgt tgcagattat attttgtcga taagccccaa tttaaaatcg aaatctgcag
    14701 aaatccgaga gtttgaggaa gcgttgcgta aaacagacca gcatcaagaa atctattcgc
    14761 ttgttcaaag ctatcttcat ctgccacgta tagctaagga aatcgaccag agtgatcaag
    14821 aatggatacg agaagaagta aagcagcatg ctactttcag aagactccaa gccttatcgc
    14881 aagaaaccca agcgacagct aaagaattaa aaacccgctt gattgcttac agacaaggaa
    14941 aacttgatgc actatgtatc cagagcattc acaaaagtaa aggtcttagt taccgaaatg
    15001 tctttttgat tggttgtaac gaaggaagtt tgccttataa cggagcgaca gaaaagaaag
    15061 taatcgactt taatgaaata aaagcagaac cagtgacgac gatagaagaa gaacgaagac
    15121 tattttatgt tgcgatgact agagcaagaa atcgtctgta tctatgtgta cctcaaatga
    15181 aaaattcaag aaaattgaaa gtatcgagat ttatcaaaga aaccgggagt cgtgtgaaaa
    15241 aaggaaagtg atagaagaga gggtgtgaca gaagtggtca gtttcaagaa agaagaagga
    15301 atgtacgaaa attgcttctc aaatttttgt gaaatttcag cttattttcg aagaagctat
    15361 ttctggaaca cagtttattc ggaaaaggga ggtgtgacaa gaattttgtc acacctccct
    15421 tatttatttt gaaaatgaga atactattat caaaatagag aatatataga aaaattctca
    15481 ttattcaaac gtaaataatc agttattttg attttttttt atatttcgcc gattgtaaaa
    15541 ttaagctaga caactaaaaa agtcatttgt gctacactca aaatagttcc gaccaaagaa
    15601 ttataaggag tgagtacaaa tgacctatac acatcttaca acggatgaac ttgtaataat
    15661 agagtcttat ttcaaaatga atcaatctgt tgctaaaact gcccattgct tgaatcgttc
    15721 aagacaaacg atccataaag tatatctgtt cttcaagcaa ggaaaatcag ccttagaata
    15781 ttatcaacag tataagaaaa acaaatcaaa ctgtggtaga cgtccgcttg ttttacccga
    15841 ggaacaatca gaatatattc aaagaaaggt tgttcaagga tggacacccg atgtgattgt
    15901 tggtcgtgca gcgtttccta ttagttgttc tgctcgtacc atttatcgta tgttcaaaaa
    15961 ggggctattt gattcttctg acttaccgat gaaaggcaag cgtaaaccga atggacatca
    16021 agaaagacgt ggaaaacaaa ctttccgccg ctctattcat gaacgtgaaa aggattatag
    16081 ccaattctca aatgagtttg gtcaccttga aggtgacact atcgtaggtc tgaaacataa
    16141 aagtgctgta attaccttag ttgaacgatt atcaaaagtt atcatcacat tgaaaccgtg
    16201 tggtagacaa gcgattgata ttgaaaaaaa ttaaatcaat ggtttgaatc tgtaccgaaa
    16261 aacctattca aatccatcac ttttgattgt ggaaaggaat tttcaaattg gaaacagatc
    16321 agtaatgtca atgatattgc catttatttc gctgatccag gaacgccgtc tcaaagaggc
    16381 ctaaacgaga attctaacgg attgttacgt agagatggtt tattgaaatc tatggatttc
    16441 aattcagtag atgaattttt tattcaatct gtcgcatcta aacgaaataa tattcctaga
    16501 aaatcactgg attatcgaac acctttggaa gtatttttga gttacgtaag tattgatgat
    16561 ctgtctaact taatttgaca attaagattt tattagctaa taattggtat tttaaaagaa
    16621 attactgtag aattggatta taattaaaaa ggagtgagaa aatgataaaa gtatatactt
    16681 cgcctagctg tacttcctgt agaaaagcaa gagcatggtt gcaagcgaat caacttgaat
    16741 ttgaagagaa gaatattttt gccgaaccgt taacagaaag tgagatcaaa aagatcttag
    16801 cagcgactga aggaggagtt caagatatta tttccactcg gtcgaaaatt tacgaaaagc
    16861 tgggcataga ttttaacgaa ttaactttaa agcaaatgat cgtcttattc aaagaatatc
    16921 cttcattatt gagacgacct attttgattg atgaaaaaag aatactaatc ggatttaatg
    16981 aagatgagat ccggtcattt gtccctcgtg aaattcgatg tgttgccaga aatctgatct
    17041 atttacaaaa caataacatc ttaaattcat agggagggag ccttcgtgga agtgaaagtc
    17101 tatggatcag cgcactgtgt aacaagtctg aaggcgaaac aatggttaga acaccatcaa
    17161 ttgccttatc aatttgttga cttagaagaa cgcgatctaa gtacagaaga agcagaagaa
    17221 ttatgcagtt ttgaagaagt gcaagcagaa cagctatttg cgacttggtc tgaggctttt
    17281 cacaacattg cgattgacct ttcctgtgta ggaaaaaaac aactgatttt tttatgcaca
    17341 caacatacca atctcctcag acgtcctttg attattatcg atgaagttct atttattgga
    17401 tacaatgagc agttgatgga acagcttatc ttaaataaat agactttaac tgttttaatc
    17461 aagtcactga gcatttcata cagttgtaac agtcgaacac ttagcatcaa gcgtgttatg
    17521 tgttcttttt ttgactttat ttttctacta tagagacatg ctcaatttat gtggtcaaaa
    17581 ttcaaatcta ggtggggata tagagttaaa aatatattga catgtgtaaa tttacatgat
    17641 atattcattt ctgttgtttt aagtagcaaa gcaataaaat agtattttaa aaaacatata
    17701 aaatagttgt tgacatgtta gaaatgacat gataagataa ctgagttgtt aaaaaagaac
    17761 cacttgtgaa gcttgattct atcgaaaaaa acttcaaaaa aagttcttga caaataacaa
    17821 atgataagtt atgataaatg agttgctgta agatttcgaa aaacgaaatc aaaaaaactt
    17881 ttaaaaaaga gttgacaatt acttgtctct ctgatatgat ataaaagttg ctacggcagc
    17941 caaaaacgaa tcggggaaca ctcctgatga agtagacctt tgaaaactga acaaagtaag
    18001 acaaaccaaa tttgtagggc gtcttgattc aattcaagac aacaaacatt ttttaacaag
    18061 caagcaatat gctagcaaac aaattgagct taacaatcgc aagattgttc gaacttttta
    18121 tgagagtttg atcctggctc aggacgaacg ctggcggcgt gcctaataca tgcaagtcga
    18181 acgcttcttt ttccaccgga gcttgctcca ccggaaaaag aggagtggcg aacgggtgag
    18241 taacacgtgg gtaacctgcc catcagaagg ggataacact tggaaacagg tgctaatacc
    18301 gtataacaat caaaaccgca tggttttgat ttgaaaggcg ctttcgggtg tcgctgatgg
    18361 atggacccgc ggtgcattag ctagttggtg aggtaacggc tcaccaaggc cacgatgcat
    18421 agccgacctg agagggtgat cggccacatt gggactgaga cacggcccaa actcctacgg
    18481 gaggcagcag tagggaatct tcggcaatgg acgaaagtct gaccgagcaa cgccgcgtga
    18541 gtgaagaagg ttttcggatc gtaaaactct gttgttagag aagaacaagg atgagagtaa
    18601 ctgttcatcc cttgacggta tctaaccaga aagccacggc taactacgtg ccagcagccg
    18661 cggtaatacg taggtggcaa gcgttgtccg gatttattgg gcgtaaagcg agcgcaggcg
    18721 gtttcttaag tctgatgtga aagcccccgg ctcaaccggg gagggtcatt ggaaactggg
    18781 agacttgagt gcagaagagg agagtggaat tccatgtgta gcggtgaaat gcgtagatat
    18841 atggaggaac accagtggcg aaggcggctc tctggtctgt aactgacgct gaggctcgaa
    18901 agcgtgggga gcaaacagga ttagataccc tggtagtcca cgccgtaaac gatgagtgct
    18961 aagtgttgga gggtttccgc ccttcagtgc tgcagctaac gcattaagca ctccgcctgg
    19021 ggagtacgac cgcaaggttg aaactcaaag gaattgacgg gggcccgcac aagcggtgga
    19081 gcatgtggtt taattcgaag caacgcgaag aaccttacca ggtcttgaca tcctttgacc
    19141 actctagaga tagagcttcc ccttcggggg caaagtgaca ggtggtgcat ggttgtcgtc
    19201 agctcgtgtc gtgagatgtt gggttaagtc ccgcaacgag cgcaaccctt attgttagtt
    19261 gccatcattc agttgggcac tctagcaaga ctgccggtga caaaccggag gaaggtgggg
    19321 atgacgtcaa atcatcatgc cccttatgac ctgggctaca cacgtgctac aatgggaagt
    19381 acaacgagtt gcgaagtcgc gaggctaagc taatctctta aagcttctct cagttcggat
    19441 tgcaggctgc aactcgcctg catgaagccg gaatcgctag taatcgcgga tcagcacgcc
    19501 gcggtgaata cgttcccggg ccttgtacac accgcccgtc acaccacgag agtttgtaac
    19561 acccgaagtc ggtgaggtaa ccttttggag ccagccgcct aaggtgggat agatgattgg
    19621 ggtgaagtcg taacaaggta gccgtatcgg aaggtgcggc tggatcacct cctttctaag
    19681 gaatattacg gagactacac aatttgtttt tactttgttc agttttgaga ggtttactct
    19741 caaacacttt tgttcattga aaactggata tttgaagtaa atgtaagtaa tacaaaccga
    19801 gaacaccgcg ttgaatttga aagctgaaca aattgtttag cctgaagcaa aataggcgga
    19861 cggccataaa atctttgatt ttatgagacg atcgatcttt ttgccgtaca ggctgatttg
    19921 tgagctggat agagtttttt aataagttca attgcttatt ttcttgatct aacttctatc
    19981 gctagaagaa ggatcaaaac ccaaccgtaa ggttgataag gttaagtgaa taagggcgca
    20041 cggtggatgc cttggcacta ggagccgatg aaggacggga ctaacaccga tatgctttgg
    20101 ggagctgtac gtaagctatg atccagagat ttccgaatgg gggaacccaa catctttaat
    20161 aggatgttac gattgtgtga atacatagca cattcgaggt agacgcagag aactgaaaca
    20221 tctaagtacc tgcaggaaga gaaagaaaat tcgattccct gagtagcggc gagcgaaacg
    20281 ggaaaagccc aaaccagcaa gcttgcttgt tggggttgta ggactccaat atggtagttc
    20341 tttcagatag tcgaatgact tggaaaagtc agtcaaagag ggtaaaaacc ccgtagacga
    20401 aatgtggaag acacctagga ggatcctgag tacggcggaa cacgagaaat tccgtcggaa
    20461 tccgggagga ccatctccca aggctaaata ctccctagtg accgatagtg aaccagtacc
    20521 gtgagggaaa ggtgaaaagc accccggaag gggagtgaaa tagaacctga aaccgtgtgc
    20581 ctacaacaag tcaaagcccg tta
//
