LOCUS       c00005_NZ_LXZX..       22187 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_LXZX01000005.1 Streptococcus vestibularis strain 22-06 S6
            SAS601000005, whole genome shotgun sequence.
ACCESSION   NZ_LXZX01000005
VERSION     NZ_LXZX01000005
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 14:07:28
            Original ID  :: NZ_LXZX01000005.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 339774
            Orig. end    :: 361961
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22187
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[349774:351961](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12187)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
     cand_cluster    1..22187
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /kind="single"
                     /product="lanthipeptide-class-iv"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..22187
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iv"
                     /region_number="2"
                     /rules="(cds(LANC_like and Pkinase) and not micKC)"
                     /tool="antismash"
     CDS             complement(906..1649)
                     /locus_tag="ctg5_339"
                     /transl_table=11
                     /translation="LLNIFILEDEFLQQTRIETVIKDVIAKKSLKCKGPEIFGKPSQLL
                     DAITERGSHQLFFLDIEIKGEEKKGLDIAKEIRKKDPNATIVFVTTHSEFMPITFKYRV
                     AALDFIDKALDDEDFYERVHLAIEYTMDKMGATIAQDSFTFETATAQVQVPFNNILFFE
                     TSPTIHKVILHTKEERMEFYASISEVERADDRLYRCHRSFIVNPENIIRINKEEKTVMF
                     ENNNECPISRTKYKGLLEKVKSLKS"
     PFAM_domain     complement(927..1196)
                     /aSDomain="LytTR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04397.17"
                     /description="LytTr DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg5_339_0009"
                     /evalue="6.60E-21"
                     /label="ctg5_339"
                     /locus_tag="ctg5_339"
                     /protein_end="241"
                     /protein_start="151"
                     /score="74.5"
                     /tool="antismash"
                     /translation="VQVPFNNILFFETSPTIHKVILHTKEERMEFYASISEVERADDRL
                     YRCHRSFIVNPENIIRINKEEKTVMFENNNECPISRTKYKGLLEK"
     PFAM_domain     complement(1281..1640)
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg5_339_0008"
                     /evalue="1.00E-10"
                     /label="ctg5_339"
                     /locus_tag="ctg5_339"
                     /protein_end="123"
                     /protein_start="3"
                     /score="41.8"
                     /tool="antismash"
                     /translation="IFILEDEFLQQTRIETVIKDVIAKKSLKCKGPEIFGKPSQLLDAI
                     TERGSHQLFFLDIEIKGEEKKGLDIAKEIRKKDPNATIVFVTTHSEFMPITFKYRVAAL
                     DFIDKALDDEDFYERV"
     CDS             2013..2375
                     /locus_tag="ctg5_340"
                     /transl_table=11
                     /translation="MLNIVKHFWLLITVKRYIKKYKLKVKIGNHFNCLRITTATNCLYF
                     IIHTKKCNYGKKVKKIRRNNVSAQIILLTPNVDYKRIFNEHLELLGVIDIKKSLAEFTN
                     EISGYLDYFFNIEKVH"
     CDS             complement(2665..2991)
                     /locus_tag="ctg5_341"
                     /transl_table=11
                     /translation="MSNLQEYISKRIRVLRIKEGMTQEMLEEKAELGTNYVYKIENLEP
                     NIKIKTLEKIMKALDVDISTFFDVTLKEEDSDLVKLIDNLKALPEYKQKKLITAINTIM
                     TETK"
     PFAM_domain     complement(2800..2958)
                     /aSDomain="HTH_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01381.24"
                     /description="Helix-turn-helix"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg5_341_0010"
                     /evalue="2.10E-11"
                     /label="ctg5_341"
                     /locus_tag="ctg5_341"
                     /protein_end="64"
                     /protein_start="11"
                     /score="43.8"
                     /tool="antismash"
                     /translation="IRVLRIKEGMTQEMLEEKAELGTNYVYKIENLEPNIKIKTLEKIM
                     KALDVDIS"
     CDS             3152..6148
                     /locus_tag="ctg5_342"
                     /transl_table=11
                     /translation="MEKKEAIKVLASVSTVIVATGLTSVANANQQEALKTEVDALSSKV
                     TVQALKEAENKQSVAVQAVNAQQDIVNQAITEEEKAEKTEAMAKEALDEAQIIKDKATL
                     AEIDKTKQNISETESAIENQDVQLQNAQAETAKAQDKVNKQTEIVNSDQTKITTQETNL
                     ANAKADVETAQKNLDGTGAKEIISERDNAQSDLATKKAVEANAKSKLEEAQKADADKKV
                     KLEQAEKDEKLQTKSVEDTSKSLSDAEAKAKQTKEQLNNANIAVTNAQAALDGTGAKEI
                     ISERDNAQSDLATKKAAESKAQSNLEEAQKTDADKKAKIQTLTETLTAQQNVALRTSTE
                     LTAAIAVAADAKSKKEEADKAVKRLEDKLTSLENLSTIEIPEEVASAYRNFYEDKSEAN
                     KDKLFDAVQTWWDNRDYSKENNYPVDDTVINDLSDLTKEQIANLSLYQAGLIQQVRKTI
                     WGDSEILVTEDVVTAMKNITTAYSNMSNPDGDHLFSALTNDGTDTTHWKAENLGYIKAK
                     PTTMSALYKGIYKSIINTFGSDYNQNYAHIITTVGGKPDYKNGKVIPNYIGAATSVTPE
                     GLGLMHEIHFNHTSSDTDKILSNPFDSSVVKTQLADAKAVQTSADNANKTAQNRLNTAS
                     VANNAAQDTVSNTTKTLNALKAIADLTPDAKAKLDEATEVRKNAESRFSNAQKSVDNLN
                     ADVATKTKALADAKVAQEKANNANKTANEELNSAQAKNKLANEVLSETRNKIASLKATA
                     DLTPDAKIKLAEATSARELAELRLVKAQKAVNNLNSDVASKTKALADAKATLQKEEAKL
                     EELKAKKAKDEKELASLQETVNALKVNEVKIKDEIKSLKTKLQETKDYLSKLENADSNL
                     EKAKVAYKLAVEKHKEAKSILDKETEKLKQLLINKHDAVTQYEAIVQKGGTPVAILNEN
                     GQIVGYNSSFSRDVRTAVRTITDNVVSKHGVPIYQASLPETGEGETAVYTLSGITFLAL
                     AGVMRKKKL"
     aSDomain        4196..5266
                     /aSDomain="TIGR04320"
                     /aSTool="tigrfam"
                     /description="Surf_Exclu_PgrA: SEC10/PgrA surface exclusion
                     domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg5_342_0001"
                     /evalue="5.20E-65"
                     /identifier="TIGR04320"
                     /label="ctg5_342"
                     /locus_tag="ctg5_342"
                     /protein_end="705"
                     /protein_start="348"
                     /score="218.0"
                     /tool="antismash"
                     /translation="ADAKSKKEEADKAVKRLEDKLTSLENLSTIEIPEEVASAYRNFYE
                     DKSEANKDKLFDAVQTWWDNRDYSKENNYPVDDTVINDLSDLTKEQIANLSLYQAGLIQ
                     QVRKTIWGDSEILVTEDVVTAMKNITTAYSNMSNPDGDHLFSALTNDGTDTTHWKAENL
                     GYIKAKPTTMSALYKGIYKSIINTFGSDYNQNYAHIITTVGGKPDYKNGKVIPNYIGAA
                     TSVTPEGLGLMHEIHFNHTSSDTDKILSNPFDSSVVKTQLADAKAVQTSADNANKTAQN
                     RLNTASVANNAAQDTVSNTTKTLNALKAIADLTPDAKAKLDEATEVRKNAESRFSNAQK
                     SVDNLNADVATKTKALA"
     PFAM_domain     6047..6142
                     /aSDomain="Gram_pos_anchor"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00746.23"
                     /description="LPXTG cell wall anchor motif"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg5_342_0011"
                     /evalue="1.90E-04"
                     /label="ctg5_342"
                     /locus_tag="ctg5_342"
                     /protein_end="997"
                     /protein_start="965"
                     /score="21.4"
                     /tool="antismash"
                     /translation="ASLPETGEGETAVYTLSGITFLALAGVMRKKK"
     aSDomain        6050..6142
                     /aSDomain="TIGR01167"
                     /aSTool="tigrfam"
                     /description="LPXTG_anchor: LPXTG cell wall anchor domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg5_342_0002"
                     /evalue="1.40E-05"
                     /identifier="TIGR01167"
                     /label="ctg5_342"
                     /locus_tag="ctg5_342"
                     /protein_end="997"
                     /protein_start="966"
                     /score="23.6"
                     /tool="antismash"
                     /translation="SLPETGEGETAVYTLSGITFLALAGVMRKKK"
     CDS             6275..6637
                     /locus_tag="ctg5_343"
                     /transl_table=11
                     /translation="MKKVLIIVSVVVIALAGIGIGAYFLTREKSPEQQVVGTWYDGEND
                     VTIELKSNKSLKITKESGESRTGTWRIAGDKIKFTATSGPKAEGELSTGKIESIFFEFT
                     NTNVSYALHDATYEKQ"
     CDS             6777..8051
                     /locus_tag="ctg5_344"
                     /transl_table=11
                     /translation="MKKWILISLLSLSTLTLVACGSNQMKQVTQQSSSSSKQSLKKNRQ
                     ESFQTVLDRYKSYQQAINSGDDSRLTEALKQVEATSEEYMLIDNLGHSGTSVDFQYAFV
                     DLDKDGHDELLIGKQDYISAIYYLKNSQPTLLHVAYAAPVGGARSSLTAYENGQVVFAA
                     WQSSNPEVSLSLYKVEASVPNKEKETTIQMNDKKKIEDELGISSTALNLKNLKWESIDK
                     GSMTSSKESDMKSSSQSENIKSETGFQVRVQISDLEIRKEPRAKSQSLGKISQGIHTIA
                     ETTNAEGYTWGRLQSGQGWIALDYTERIEGEKKTQSESSGMNIQEIQTGNFSSVKGSWR
                     NEQGNSITFDANGLIQVNGKPAGDVVFDKFVVKGEKLTAVTKTSEGISETPIVFTPSGQ
                     DGRESIILSIHRRPHSYLLLSLDRR"
     PFAM_domain     7734..7835
                     /aSDomain="DUF6287"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF19804.1"
                     /description="Domain of unknown function (DUF6287)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg5_344_0012"
                     /evalue="1.20E-11"
                     /label="ctg5_344"
                     /locus_tag="ctg5_344"
                     /protein_end="353"
                     /protein_start="319"
                     /score="43.8"
                     /tool="antismash"
                     /translation="SGMNIQEIQTGNFSSVKGSWRNEQGNSITFDANG"
     CDS             complement(8458..10026)
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 138.4; E-value:
                     5.4e-42)"
                     /gene_kind="transport"
                     /locus_tag="ctg5_345"
                     /transl_table=11
                     /translation="MKKYILQFKFKNLLHIFLIACNSAFLVGASVTLAFMTNQLVAGNF
                     KLFLIWLGIEISLYLLYLIFTYMINIHQAKLIQEMSLKIRSDYIKNITNASFHTFQSKT
                     IGDHISILNNDIQIIENSGFSNLYNLFSTLFTTIFSIIALLSYDIRIVVLTIILTICLT
                     YLPKPFATKMQNFMSLFSTANEELISGLNDQLTGYKTLYYSSKKPTLLIQTTKIIRNYI
                     TQKVKFTQNSTRIEIIMSTFSIIAQVSILFLTGLLITLGQVSIGSISSVGQISGNIFNS
                     LTTLNQLQVSIHSVKPLFLKFEISSKNTEKKIVNNIEKIDIFDLEYNFGNKKVFSKLNL
                     NLIKNNKYAIIGESGSGKSTLINIILGNLKNYTGHVKYNNLELKEIDENSIVSQVAYIS
                     NSTHIYNDTLENNLTLWSQDITQNEIKKALKDVNLLDLLGRLKESVSNDLLSEGQKQRI
                     GIARALLKGSKIIIMDEATANLDKTNSDFIENNILKNTDITYITVTHHLSSEREKYFDQ
                     IIKLA"
     PFAM_domain     complement(8593..9018)
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg5_345_0014"
                     /evalue="3.30E-28"
                     /label="ctg5_345"
                     /locus_tag="ctg5_345"
                     /protein_end="478"
                     /protein_start="336"
                     /score="99.0"
                     /tool="antismash"
                     /translation="KLNLNLIKNNKYAIIGESGSGKSTLINIILGNLKNYTGHVKYNNL
                     ELKEIDENSIVSQVAYISNSTHIYNDTLENNLTLWSQDITQNEIKKALKDVNLLDLLGR
                     LKESVSNDLLSEGQKQRIGIARALLKGSKIIIMDEATA"
     PFAM_domain     complement(9205..9981)
                     /aSDomain="ABC_membrane"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00664.25"
                     /description="ABC transporter transmembrane region"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg5_345_0013"
                     /evalue="6.40E-12"
                     /label="ctg5_345"
                     /locus_tag="ctg5_345"
                     /protein_end="274"
                     /protein_start="15"
                     /score="45.8"
                     /tool="antismash"
                     /translation="IFLIACNSAFLVGASVTLAFMTNQLVAGNFKLFLIWLGIEISLYL
                     LYLIFTYMINIHQAKLIQEMSLKIRSDYIKNITNASFHTFQSKTIGDHISILNNDIQII
                     ENSGFSNLYNLFSTLFTTIFSIIALLSYDIRIVVLTIILTICLTYLPKPFATKMQNFMS
                     LFSTANEELISGLNDQLTGYKTLYYSSKKPTLLIQTTKIIRNYITQKVKFTQNSTRIEI
                     IMSTFSIIAQVSILFLTGLLITLGQVSIGSISSVGQI"
     CDS             complement(10001..12187)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: Pkinase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_346"
                     /sec_met_domain="LANC_like (E-value: 4.8e-08, bitscore:
                     28.9, seeds: 47, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 3e-14, bitscore: 49.8,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIDTMIFPTNLSPDNLIINSNFTYVFSTNKSIPYQGWKIHISATL
                     DNYQKILDSVTTICLTNDTPFKFINSIEKLLFIFSKKTSQTEIGKFITIYPENDQTFLY
                     LLDVLYQEIKYEPGIQIITDQNYKQSEVIFYRYGLMNASVKNGQRPCLFDNNGVAYPDL
                     PGAYYSCPKFVKEYFPEKTNTSTILNERYDMKSILYQTGAGNIYIAIDITNSKKVIIKE
                     ARRYVYATRDITSMELLKNETKIIKKLSGSVTPNYIDDFYLEDNYYLVEEFIEGKTLNT
                     LKTDFNLLLKRTPSEITTFNNKLKQIISKLFKSLEYIHDHGVIVDDISCSNIILTPENK
                     VYFIDFETAYLKNENPLIATTNSCYPKTIYAKFEHKDIVKLWYCIINLLTNASSLLKFD
                     QTGTETLKLFTKICLEMNFPLQLLNKFMKDFKLERNNQIFFINFIKLGMDLEKLIYKRD
                     QLLNTLVTSSTISIEGKSWCEKVDNYLAINQLGLNLSEKITKRDIQGSDLDSQLAKILL
                     DESQENLSDDMLSEDFFKDLEYEEKYRLLTILNSKQKKTNLFRKLVKSIISNNIKYEKD
                     VPYLIIEDYLSPYLVNGNSGLIIELIKFSISEQTTEYDDFIKKLGKGVEHPYAKSTSLY
                     NGLAGLGLANAWLYHYFDKIHYLETSINIVNHICDYSIEKNGKFILIDPICDEIKYSYS
                     HGMLGQFYFFETLISLISKVQNTDKNYEKIHLTI"
     PFAM_domain     complement(11126..11584)
                     /aSDomain="Pkinase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00069.27"
                     /description="Protein kinase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg5_346_0015"
                     /evalue="2.50E-14"
                     /label="ctg5_346"
                     /locus_tag="ctg5_346"
                     /protein_end="354"
                     /protein_start="201"
                     /score="53.4"
                     /tool="antismash"
                     /translation="GAGNIYIAIDITNSKKVIIKEARRYVYATRDITSMELLKNETKII
                     KKLSGSVTPNYIDDFYLEDNYYLVEEFIEGKTLNTLKTDFNLLLKRTPSEITTFNNKLK
                     QIISKLFKSLEYIHDHGVIVDDISCSNIILTPENKVYFIDFETAYLKNE"
     CDS             complement(12282..13154)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR01716"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg5_347"
                     /sec_met_domain="TIGR01716 (E-value: 1.5e-36, bitscore:
                     122.8, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIETTEMGALFKKIRLSKKLALKDVAGDYLSISFLSKFERGESEI
                     SLSRFFLLLENLDVSIEEFYGILSKEKPTYTELLLERVSKAYYQNNILALKKYLKEENK
                     KYHDSNKKLFLYNTIMIESFLSTITEEDVDEDKIKIITDYLFDIEQWGKRELIILGNSM
                     PAISSETLNVLVKEVIYRTTLFGNNESNLKIRIDLLINATSEFIERNQLDLAKSYLDII
                     SDIGIPEIFLHEKLEYNMLLGAFWMKSGKVEIGKKLIENCLSVLKTLGANNLLVSHEAY
                     YEELLDSTI"
     aSDomain        complement(12297..12956)
                     /aSDomain="TIGR01716"
                     /aSTool="tigrfam"
                     /description="RGG_Cterm: transcriptional activator,
                     Rgg/GadR/MutR family, C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg5_347_0003"
                     /evalue="3.60E-36"
                     /identifier="TIGR01716"
                     /label="ctg5_347"
                     /locus_tag="ctg5_347"
                     /protein_end="286"
                     /protein_start="66"
                     /score="122.8"
                     /tool="antismash"
                     /translation="ILSKEKPTYTELLLERVSKAYYQNNILALKKYLKEENKKYHDSNK
                     KLFLYNTIMIESFLSTITEEDVDEDKIKIITDYLFDIEQWGKRELIILGNSMPAISSET
                     LNVLVKEVIYRTTLFGNNESNLKIRIDLLINATSEFIERNQLDLAKSYLDIISDIGIPE
                     IFLHEKLEYNMLLGAFWMKSGKVEIGKKLIENCLSVLKTLGANNLLVSHEAYYEELL"
     PFAM_domain     complement(12963..13121)
                     /aSDomain="HTH_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01381.24"
                     /description="Helix-turn-helix"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg5_347_0016"
                     /evalue="2.60E-06"
                     /label="ctg5_347"
                     /locus_tag="ctg5_347"
                     /protein_end="64"
                     /protein_start="11"
                     /score="27.5"
                     /tool="antismash"
                     /translation="KKIRLSKKLALKDVAGDYLSISFLSKFERGESEISLSRFFLLLEN
                     LDVSIEEF"
     CDS             13726..14052
                     /locus_tag="ctg5_348"
                     /transl_table=11
                     /translation="MTKSNNTQIDDIMNNIYNLILNPETTENERKLLVTFKNEIEVGKK
                     DSSELLAELRRAIQVLAVENLPKGISLSYGVSELSKTLAEFQDESERNINLARGLSSIA
                     MSFR"
     PFAM_domain     13756..13968
                     /aSDomain="EntA_Immun"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08951.12"
                     /description="Enterocin A Immunity"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg5_348_0017"
                     /evalue="1.90E-12"
                     /label="ctg5_348"
                     /locus_tag="ctg5_348"
                     /protein_end="81"
                     /protein_start="10"
                     /score="47.3"
                     /tool="antismash"
                     /translation="DIMNNIYNLILNPETTENERKLLVTFKNEIEVGKKDSSELLAELR
                     RAIQVLAVENLPKGISLSYGVSELSK"
     CDS             complement(14202..15461)
                     /locus_tag="ctg5_349"
                     /transl_table=11
                     /translation="MTIDFPNETETQNEMDAILQAGRVLMESGAEIYRIEDTMGHMAKS
                     LGIRDFSTYVVNRGVMISGLNRSGLKESRVLATSVPSIHLGKLEEVNRLSRELAEQPNQ
                     PVSSIFQKLKTIEQKTFYRPLEDIIACVIGAGSFSLALGSGLIDGTAAAISGLFVGIGM
                     QLFSRFIHTSFLQIILSSAIAALSANILYYLGIGQHRSVIILGALMILIPGAYFVNAIR
                     EFTQNNYYSGLALMLSGVSTCLSISVGVLAMISLLPFAEQLSGMFSTPTTSWQEVLIQT
                     VMAGLGTAAFSVLYRVPKKYFLDLGTLGAGSWLLYLLIWNNTHHEVLAILFPALLVTFT
                     SRFLAHYRRCPATVFLASSMFPLIPGMSFYRAIYFLLIGNADLGLNFLRACFLASFTIA
                     IAVSLTQQIPSHYFVLGKKK"
     PFAM_domain     complement(14244..14624)
                     /aSDomain="ThrE_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12821.9"
                     /description="Threonine/Serine exporter, ThrE"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg5_349_0019"
                     /evalue="7.90E-23"
                     /label="ctg5_349"
                     /locus_tag="ctg5_349"
                     /protein_end="406"
                     /protein_start="279"
                     /score="81.1"
                     /tool="antismash"
                     /translation="QTVMAGLGTAAFSVLYRVPKKYFLDLGTLGAGSWLLYLLIWNNTH
                     HEVLAILFPALLVTFTSRFLAHYRRCPATVFLASSMFPLIPGMSFYRAIYFLLIGNADL
                     GLNFLRACFLASFTIAIAVSLTQ"
     PFAM_domain     complement(14694..15413)
                     /aSDomain="ThrE"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06738.14"
                     /description="Putative threonine/serine exporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg5_349_0018"
                     /evalue="1.40E-48"
                     /label="ctg5_349"
                     /locus_tag="ctg5_349"
                     /protein_end="256"
                     /protein_start="16"
                     /score="165.5"
                     /tool="antismash"
                     /translation="AILQAGRVLMESGAEIYRIEDTMGHMAKSLGIRDFSTYVVNRGVM
                     ISGLNRSGLKESRVLATSVPSIHLGKLEEVNRLSRELAEQPNQPVSSIFQKLKTIEQKT
                     FYRPLEDIIACVIGAGSFSLALGSGLIDGTAAAISGLFVGIGMQLFSRFIHTSFLQIIL
                     SSAIAALSANILYYLGIGQHRSVIILGALMILIPGAYFVNAIREFTQNNYYSGLALMLS
                     GVSTCLSISVGVLAMISL"
     aSDomain        15787..16773
                     /aSDomain="TIGR02363"
                     /aSTool="tigrfam"
                     /description="dhaK1: dihydroxyacetone kinase, DhaK subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg5_350_0004"
                     /evalue="2.30E-152"
                     /identifier="TIGR02363"
                     /label="ctg5_350"
                     /locus_tag="ctg5_350"
                     /protein_end="329"
                     /protein_start="0"
                     /score="504.7"
                     /tool="antismash"
                     /translation="MKKIINKPENIVTEMLDGLAYVHNDLVHRVEGFDIIARNEQVAGQ
                     VGLISGGGSGHEPAHAGFVGDGMLSAAIAGAVFTSPTPDQILEAIKEADQGAGVFMVVK
                     NYSGDIMNFEMAQELAEMEGIEVASVVVDDDIAVENSLYTQGRRGVAGTIFVHKILGHA
                     AREGKSLAEIKDLADKIVPNIHTIGLALSGATVPEVGKPGFVLAEDEIEYGIGIHGEPG
                     YRKESMQPSRQLAEELTGKLLESFDAKSGDRYALLINGMGATPLMEQYVFANDVASLLR
                     DAGLEVIYRKLGNYMTSIDMAGLSLTLMKIEDDAWLEALESPVKTIAW"
     CDS             15787..16776
                     /locus_tag="ctg5_350"
                     /transl_table=11
                     /translation="MKKIINKPENIVTEMLDGLAYVHNDLVHRVEGFDIIARNEQVAGQ
                     VGLISGGGSGHEPAHAGFVGDGMLSAAIAGAVFTSPTPDQILEAIKEADQGAGVFMVVK
                     NYSGDIMNFEMAQELAEMEGIEVASVVVDDDIAVENSLYTQGRRGVAGTIFVHKILGHA
                     AREGKSLAEIKDLADKIVPNIHTIGLALSGATVPEVGKPGFVLAEDEIEYGIGIHGEPG
                     YRKESMQPSRQLAEELTGKLLESFDAKSGDRYALLINGMGATPLMEQYVFANDVASLLR
                     DAGLEVIYRKLGNYMTSIDMAGLSLTLMKIEDDAWLEALESPVKTIAW"
     PFAM_domain     15838..16767
                     /aSDomain="Dak1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02733.19"
                     /description="Dak1 domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg5_350_0020"
                     /evalue="7.60E-120"
                     /label="ctg5_350"
                     /locus_tag="ctg5_350"
                     /protein_end="327"
                     /protein_start="17"
                     /score="399.6"
                     /tool="antismash"
                     /translation="GLAYVHNDLVHRVEGFDIIARNEQVAGQVGLISGGGSGHEPAHAG
                     FVGDGMLSAAIAGAVFTSPTPDQILEAIKEADQGAGVFMVVKNYSGDIMNFEMAQELAE
                     MEGIEVASVVVDDDIAVENSLYTQGRRGVAGTIFVHKILGHAAREGKSLAEIKDLADKI
                     VPNIHTIGLALSGATVPEVGKPGFVLAEDEIEYGIGIHGEPGYRKESMQPSRQLAEELT
                     GKLLESFDAKSGDRYALLINGMGATPLMEQYVFANDVASLLRDAGLEVIYRKLGNYMTS
                     IDMAGLSLTLMKIEDDAWLEALESPVKTI"
     CDS             16807..17382
                     /locus_tag="ctg5_351"
                     /transl_table=11
                     /translation="MDKIVAVKWMQVFNQKVEAEKDHLSELDGPIGDGDHGANLARGMA
                     AAVEAINTSDPQSTADVLKTVSMALISKVGGASGPLYGSAFMGMMKAEQAGQDLAGVLE
                     AGADMIEKRGHAQVGEKTMIDVWRPVIEAVKRDQLTNEVIDQAVLSTKDVVATKGRASY
                     VGERSIGHIDPGSYSSGLLFKALLEAEG"
     aSDomain        16825..17367
                     /aSDomain="TIGR02365"
                     /aSTool="tigrfam"
                     /description="dha_L_ycgS: dihydroxyacetone kinase, L
                     subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg5_351_0005"
                     /evalue="4.10E-67"
                     /identifier="TIGR02365"
                     /label="ctg5_351"
                     /locus_tag="ctg5_351"
                     /protein_end="187"
                     /protein_start="6"
                     /score="223.7"
                     /tool="antismash"
                     /translation="VKWMQVFNQKVEAEKDHLSELDGPIGDGDHGANLARGMAAAVEAI
                     NTSDPQSTADVLKTVSMALISKVGGASGPLYGSAFMGMMKAEQAGQDLAGVLEAGADMI
                     EKRGHAQVGEKTMIDVWRPVIEAVKRDQLTNEVIDQAVLSTKDVVATKGRASYVGERSI
                     GHIDPGSYSSGLLFKALL"
     PFAM_domain     16894..17367
                     /aSDomain="Dak2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02734.19"
                     /description="DAK2 domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg5_351_0021"
                     /evalue="1.20E-46"
                     /label="ctg5_351"
                     /locus_tag="ctg5_351"
                     /protein_end="187"
                     /protein_start="29"
                     /score="158.9"
                     /tool="antismash"
                     /translation="PIGDGDHGANLARGMAAAVEAINTSDPQSTADVLKTVSMALISKV
                     GGASGPLYGSAFMGMMKAEQAGQDLAGVLEAGADMIEKRGHAQVGEKTMIDVWRPVIEA
                     VKRDQLTNEVIDQAVLSTKDVVATKGRASYVGERSIGHIDPGSYSSGLLFKALL"
     CDS             17386..17760
                     /locus_tag="ctg5_352"
                     /transl_table=11
                     /translation="MSELGIVIVSHSADIAKGLVSLIREVAPNIPLTATGGLEDGGLGS
                     SFDHVQVAVDSQPAKRLLAFYDLGSARMNLEMVEEFSEKDILIQHVPLIEGAYTASALL
                     QAGASEVEILSQVNELTIQK"
     PFAM_domain     17398..17709
                     /aSDomain="EIIA-man"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03610.18"
                     /description="PTS system fructose IIA component"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg5_352_0022"
                     /evalue="1.40E-20"
                     /label="ctg5_352"
                     /locus_tag="ctg5_352"
                     /protein_end="108"
                     /protein_start="4"
                     /score="73.6"
                     /tool="antismash"
                     /translation="GIVIVSHSADIAKGLVSLIREVAPNIPLTATGGLEDGGLGSSFDH
                     VQVAVDSQPAKRLLAFYDLGSARMNLEMVEEFSEKDILIQHVPLIEGAYTASALLQAGA
                     "
     aSDomain        17398..17742
                     /aSDomain="TIGR02364"
                     /aSTool="tigrfam"
                     /description="dha_pts: dihydroxyacetone kinase,
                     phosphotransfer subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg5_352_0006"
                     /evalue="7.30E-33"
                     /identifier="TIGR02364"
                     /label="ctg5_352"
                     /locus_tag="ctg5_352"
                     /protein_end="119"
                     /protein_start="4"
                     /score="111.5"
                     /tool="antismash"
                     /translation="GIVIVSHSADIAKGLVSLIREVAPNIPLTATGGLEDGGLGSSFDH
                     VQVAVDSQPAKRLLAFYDLGSARMNLEMVEEFSEKDILIQHVPLIEGAYTASALLQAGA
                     SEVEILSQVNE"
     CDS             17774..18757
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079:oxidoreductase (Score: 173.4; E-value: 1.4e-52)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg5_353"
                     /transl_table=11
                     /translation="MENQIKYRWASLGTGVIANELAQALEALGGKLYSVANRTYDKGVA
                     FAEKYGIEKVYKEIDQVFEDPEVDIIYISTPHNTHINFLRKALAAGKHVLCEKSITLNS
                     EELAEAIQLAEENHVKLAEAMTIFHMPIYRRLSEIVESGKLGPLKVIQMNFGSYKEYDM
                     TNRFFNRNLAGGALLDIGVYALSFVRWFMTSQPTEMVSQVKLAPTGVDEQAGILLTNAE
                     GEMATVTLSLHAKQPKRGTIAYDKGYIEIYEYPRGQKAVITYTEDGSQEVIEVGETAKA
                     LQYEVLDMEAAVSGQENHLYLNYSQDVMELMTRLRKDWGLVYPEEE"
     PFAM_domain     17795..18139
                     /aSDomain="GFO_IDH_MocA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01408.24"
                     /description="Oxidoreductase family, NAD-binding Rossmann
                     fold"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg5_353_0023"
                     /evalue="4.80E-20"
                     /label="ctg5_353"
                     /locus_tag="ctg5_353"
                     /protein_end="122"
                     /protein_start="7"
                     /score="72.6"
                     /tool="antismash"
                     /translation="RWASLGTGVIANELAQALEALGGKLYSVANRTYDKGVAFAEKYGI
                     EKVYKEIDQVFEDPEVDIIYISTPHNTHINFLRKALAAGKHVLCEKSITLNSEELAEAI
                     QLAEENHVKLA"
     PFAM_domain     18185..18682
                     /aSDomain="GFO_IDH_MocA_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02894.19"
                     /description="Oxidoreductase family, C-terminal alpha/beta
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg5_353_0024"
                     /evalue="5.30E-06"
                     /label="ctg5_353"
                     /locus_tag="ctg5_353"
                     /protein_end="303"
                     /protein_start="137"
                     /score="26.4"
                     /tool="antismash"
                     /translation="EIVESGKLGPLKVIQMNFGSYKEYDMTNRFFNRNLAGGALLDIGV
                     YALSFVRWFMTSQPTEMVSQVKLAPTGVDEQAGILLTNAEGEMATVTLSLHAKQPKRGT
                     IAYDKGYIEIYEYPRGQKAVITYTEDGSQEVIEVGETAKALQYEVLDMEAAVSGQENHL
                     YLN"
     CDS             complement(18806..19999)
                     /gene_functions="other (smcogs) SMCOG1094:ferredoxin
                     (Score: 94.3; E-value: 1.2e-28)"
                     /gene_kind="other"
                     /locus_tag="ctg5_354"
                     /transl_table=11
                     /translation="VKSYKGILLLTVSIVLTVYAWLARGMTNFIAPGLALTTLSWTFML
                     ATRSRVLEKLFNGIERMYAVHKFLAILSVVLLVFHNIGMGSLWGSRLAAQLGNLGIYTF
                     LAIVVLVFLGKTLKYETWRWLHRLVYLAYIFGLSHVYLILGHVLTKLNLLSLVVGGFAI
                     LGLSSGFYIIFLYQIFGFKNRGKIVGLKRINHDTTEIAIRLTRPMDYQFGQFTFIKILQ
                     AGFEKAPHPFSISGGHGNIIYFTVKASGDHTKQIYKKLRVGSPVAIDRAYGHMLLDQGR
                     DKQVWIAGGIGITPFISYIRENPVLDRDVDFYYAYTGEQNAVYLEMLAAYAAKNRNFKL
                     HTINSQVDGYLDFTDYPLTDDTTVFMCGPVKMMEAFAKTFTANNPKAELVYEGFSFK"
     PFAM_domain     complement(18869..19141)
                     /aSDomain="NAD_binding_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00175.23"
                     /description="Oxidoreductase NAD-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg5_354_0027"
                     /evalue="4.60E-07"
                     /label="ctg5_354"
                     /locus_tag="ctg5_354"
                     /protein_end="377"
                     /protein_start="286"
                     /score="30.6"
                     /tool="antismash"
                     /translation="IAGGIGITPFISYIRENPVLDRDVDFYYAYTGEQNAVYLEMLAAY
                     AAKNRNFKLHTINSQVDGYLDFTDYPLTDDTTVFMCGPVKMMEAFA"
     PFAM_domain     complement(19208..19432)
                     /aSDomain="FAD_binding_8"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08022.14"
                     /description="FAD-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg5_354_0026"
                     /evalue="1.20E-04"
                     /label="ctg5_354"
                     /locus_tag="ctg5_354"
                     /protein_end="264"
                     /protein_start="189"
                     /score="22.2"
                     /tool="antismash"
                     /translation="LKRINHDTTEIAIRLTRPMDYQFGQFTFIKILQAGFEKAPHPFSI
                     SGGHGNIIYFTVKASGDHTKQIYKKLRVGS"
     PFAM_domain     complement(19592..19900)
                     /aSDomain="Ferric_reduct"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01794.21"
                     /description="Ferric reductase like transmembrane
                     component"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg5_354_0025"
                     /evalue="4.10E-07"
                     /label="ctg5_354"
                     /locus_tag="ctg5_354"
                     /protein_end="136"
                     /protein_start="33"
                     /score="30.2"
                     /tool="antismash"
                     /translation="LALTTLSWTFMLATRSRVLEKLFNGIERMYAVHKFLAILSVVLLV
                     FHNIGMGSLWGSRLAAQLGNLGIYTFLAIVVLVFLGKTLKYETWRWLHRLVYLAYIFG"
     CDS             20259..20603
                     /locus_tag="ctg5_355"
                     /transl_table=11
                     /translation="VASIRIEASKVARKSPIRVDTSLVGAVSGVEAVTVYLPSSKARLS
                     VGKLGYKSNTITVEDGQTVRVTSNFLNRFIAIAPLFLYLFGGRYLSLVAALSTIILLFS
                     LPFLKLEIVG"
ORIGIN
        1 atagcatcat tcttaatatt actaagttta gcaatatcaa acttactatc atagaattga
       61 tttccactat ctcttaggac accattgtat acagttttaa tagcttcgat atcttgagta
      121 tcaattccta attttagact ggtcaaaata ttaatatagt catgacggaa acttctaatt
      181 tcctcataaa gtgattcaac atgatggctg taactagata gttcatttag ttgagtatcc
      241 ttctgctcaa ttatttcctt ctctagtttt tcttttgaaa ttgcattgag atagagtaga
      301 attacaaaaa acagaacaat ataaaagtta ttaatatgtc ctctccagat atctgcatca
      361 gctaatttgt ctctataaat aacaagtaaa gaaactaaga gcatatatgc aaacatagag
      421 atgttgatca gtaataataa atacttgaaa tagtaacgct tgaaaccttc ttttatttcg
      481 tcaaaatcta acctaagaga ttttactatg agtaaatgaa gagggaaaac cagtaattga
      541 attaagatat cataccaact tagtttgact tcattgaaga ctgagactcc tagtaaaggg
      601 aaaacgtaga atcctaacat tctacctagt aagctttcaa cgataacggg gtacaagcca
      661 taaaaaatat caagtatttt acttttatac ttattttgat atatgttata agcgataaag
      721 ataaaaaaga aagcaaagta tccaacagga ggacatatga tgaggagtag aacgtacaaa
      781 aatggaccaa taatatacca caaaggtttg attggttggt tactaacctg ttgaaacagt
      841 aacaatacta ctaatgtctt agaataaaaa agcaataaat ttataactat atccatagaa
      901 acaccttagc ttttcagaga tttaactttt tctaggaggc ccttatattt cgtacgcgaa
      961 atgggacatt cattattatt ttcaaacatt accgttttct cttccttatt gatccttatg
     1021 atattttcag gattaacgat aaatgaacga tggcatcgat ataggcgatc atcagctcgt
     1081 tcaacttctg aaatactggc gtagaactcc atgcgttctt ctttagtatg caaaataact
     1141 ttatgtattg ttggagatgt ttcaaaaaat aagatattgt taaaaggcac ttgaacttgg
     1201 gccgtagccg tttcaaaagt aaatgaatct tgggcaatag tggcacccat tttatccatg
     1261 gtatattcaa ttgctaaatg aacacgttca taaaaatctt catcatccaa agctttatca
     1321 ataaaatcca gtgcagcaac tctatattta aaagtgattg gcataaattc tgaatgtgtt
     1381 gttacaaaaa caattgttgc attagggtct tttttccgaa tttcttttgc aatgtctagc
     1441 cctttttttt cttctccttt aatttcaata tctaaaaaga aaagttgatg agaacctctt
     1501 tcggtaatcg catcaagtag ctggctaggt tttccaaaaa tctcaggtcc tttacatttt
     1561 agagattttt ttgcaataac atccttaata acggtctcta ttcgtgtttg ttgtaaaaat
     1621 tcgtcttcta aaataaaaat atttaacaat tagtgtactc ctcattcgct aaaatattta
     1681 gtaactgtgt tttatttctc ctaaaacaaa agacatcgaa gtcttttcca atattaaaaa
     1741 ttatatgact tgttgtttta gataagaatg atattattta ggggtaattg atgcatttct
     1801 atagcatcta aataaaaatc aatatttctt ctccaagtta atattgtaaa agtagtgatt
     1861 ggaataatag aaccgtcaag tcgtaaatag tctgagaaca atcatcatcg ttatattttt
     1921 atcgtagatg acaataaatg aaccgtttac gatattcaac taattgaatg gtataaccaa
     1981 gctataataa aaatagaaat tggaggagag gtatgctcaa tattgtaaag cacttttggt
     2041 tgttgattac tgtaaaaagg tatataaaaa aatataagtt aaaagttaaa attggcaacc
     2101 attttaattg tttaagaatt actacagcaa ccaattgtct atattttatc atacatacaa
     2161 agaaatgtaa ctatggaaaa aaagtcaaaa aaattaggcg aaataacgtt agtgcacaaa
     2221 ttattttatt gacaccaaat gttgattata aaagaatatt caatgaacat ctcgaactct
     2281 taggtgttat tgatataaaa aaatcattag cggaatttac taatgaaatt agtggatatc
     2341 tagattactt ttttaatatc gaaaaggtgc actaacctcc atgtacatgt aaactgtact
     2401 tgaggttatt ttttatcatc ctattaaatc gtttttcgat attttatcgt aacaaacgtt
     2461 tatttatgca tgttataaca aacaaagctc aaatctggaa cttttgaaac aaggatgtac
     2521 ttttgtatgg aatagaaatc gatttatata tcacaatgat aaataaagaa agttaaaaag
     2581 acttatctct tatattttat agagataagt cttttactta aattctattt taacctatag
     2641 tagttgtcag tttaaaaggt tctgttattt tgtttcagtc ataatagtat tgatagctgt
     2701 gattaatttc ttttgtttgt actcaggcaa tgcttttaaa ttatcaataa gttttaccaa
     2761 atcgctatct tcttctttta gtgtgacatc aaagaaagtg gagatatcca catctaaggc
     2821 tttcataatt ttttcaagag ttttgatttt aatattaggt tctagatttt caattttata
     2881 aacgtaattt gtccctaatt cagctttttc ttcaagcatt tcttgagtca ttccctcttt
     2941 tattcgtaag actctaatac gcttactgat atattcttgt agatttgaca taaaccacct
     3001 cacagggtta attttacaac cttaaaaggt tggttataac accttaaaag gttaaaaaca
     3061 actttacaag gttgttttta agttatataa tgtaaacatt acaatatagg aattgtataa
     3121 tttattgaaa attaaaggag ttttagcgtt aatggaaaag aaagaagcta taaaggtatt
     3181 agctagtgta tctacagtga ttgtagcgac aggattaacg tctgtagcga atgctaatca
     3241 acaagaagcc ctaaaaacag aagttgatgc cttaagttct aaagtgactg ttcaagctct
     3301 taaagaagct gagaacaagc aaagtgtagc ggtacaagca gtaaatgctc aacaagatat
     3361 agttaatcaa gccatcactg aagaagaaaa agctgaaaaa actgaagcta tggctaagga
     3421 agctcttgat gaagcgcaaa ttatcaaaga taaggccact cttgctgaaa ttgataaaac
     3481 taaacaaaat attagtgaaa cagaatcagc aatcgaaaat caagatgttc aacttcagaa
     3541 tgctcaagct gagactgcta aagctcaaga taaagttaac aaacaaactg aaattgttaa
     3601 cagtgatcaa acaaaaatta ctactcaaga aactaattta gcaaatgcta aagccgatgt
     3661 agaaactgct caaaaaaatc ttgatggtac aggagctaaa gaaatcatct cagaacgaga
     3721 taatgctcaa agtgatttgg caacgaaaaa agctgttgaa gctaatgcca aaagcaagct
     3781 agaagaagca cagaaagctg atgctgataa aaaagttaaa cttgaacaag ctgaaaaaga
     3841 tgaaaaactt caaactaaat ctgttgaaga cacttctaaa agtttgagcg atgctgaggc
     3901 taaggctaaa cagactaaag agcaactcaa taatgctaat attgctgtaa ctaatgctca
     3961 agcagcactt gatggtacag gagctaaaga aatcatctca gagcgagata atgctcaaag
     4021 tgatttggca acgaaaaaag ctgctgaatc caaggctcaa agcaatctag aagaagcaca
     4081 aaagactgat gctgataaaa aagctaaaat ccaaacattg acagaaactt tgactgctca
     4141 acaaaatgta gctttgagaa cttcaacgga attgacagct gctatagctg ttgcggctga
     4201 tgctaagtct aaaaaagaag aagcagacaa agctgtaaaa cggttggaag ataaactaac
     4261 tagtttagaa aatcttagca ctattgaaat tccagaagaa gttgcaagtg cttatcgaaa
     4321 cttctatgaa gataaatcag aagcaaacaa agataagctc ttcgatgctg ttcaaacttg
     4381 gtgggataac cgtgattata gcaaagaaaa caactatcct gttgacgaca ctgtaattaa
     4441 tgatcttagt gatttaacaa aagaacaaat tgctaacctc tcactttatc aggcaggatt
     4501 gattcaacaa gtgcgaaaaa ctatctgggg tgattctgaa attcttgtga cagaagatgt
     4561 tgttacagca atgaagaata tcacaactgc ttattcgaac atgtcaaatc ctgatggtga
     4621 ccatcttttt agtgctctaa ctaatgatgg aactgatact acgcattgga aggcagaaaa
     4681 cctcggttac atcaaagcta aaccaactac aatgtcggct ttgtataaag gtatttataa
     4741 atctattatc aatacttttg gtagtgacta caatcagaat tatgcacata ttattacaac
     4801 agttggagga aaacctgact ataaaaacgg taaggttatt ccaaattata ttggtgctgc
     4861 aacaagcgta acaccagaag gtcttggatt gatgcatgaa attcatttca atcacacttc
     4921 gtcagatact gataaaatat taagtaatcc atttgactct tcggttgtaa aaactcaact
     4981 agctgacgct aaagctgttc aaacttctgc ggataatgct aacaaaacag cccaaaaccg
     5041 attaaataca gcatcagtag caaataacgc agctcaggat actgtatcta acacaacaaa
     5101 aactttgaac gcactcaaag caattgctga cctcacacct gatgccaaag ctaagttgga
     5161 tgaagctact gaggtacgta agaatgcaga aagtcgattc agtaacgctc aaaaatcagt
     5221 tgacaatctt aacgctgatg ttgctactaa aactaaagct cttgcggatg caaaagtagc
     5281 acaagaaaaa gccaacaacg caaacaaaac agcaaatgaa gaattgaatt ctgcgcaggc
     5341 taaaaataaa cttgctaatg aagtgctctc agaaactcgc aataaaattg cctcactcaa
     5401 agcaactgct gacctcacac ctgatgctaa aatcaaattg gctgaagcga cttcggcgcg
     5461 tgaattagct gagctaagat tagtcaaagc tcaaaaagct gttaataatc ttaactcaga
     5521 tgttgcaagt aagactaaag ctcttgcgga tgctaaagca acacttcaaa aagaagaagc
     5581 taagttggaa gaacttaaag ctaaaaaagc gaaagacgaa aaagaacttg cttctcttca
     5641 agaaacagtg aacgctttga aagtgaatga agttaaaatc aaagacgaga ttaaatctct
     5701 taaaactaaa cttcaagaaa caaaagatta tcttagtaaa ctcgaaaatg ctgatagtaa
     5761 tttagaaaaa gctaaagttg cttacaaact agcagtagaa aaacataaag aagctaaatc
     5821 aattcttgat aaagaaactg aaaaacttaa acagttgctt atcaataaac atgatgcagt
     5881 aactcaatat gaagctattg ttcaaaaagg tggaactcct gttgctatcc ttaatgaaaa
     5941 tggccaaata gtaggttata actcttcatt ttcccgagat gtcagaactg ctgttcgcac
     6001 tattaccgat aatgtcgttt cgaaacatgg tgtaccgatc tatcaagcat cattacctga
     6061 aacaggtgaa ggtgagacag cggtttatac gctttcagga attacgtttc ttgctttagc
     6121 aggagtgatg agaaagaaga agttataaat gacagtttct aaattgcttt actgagtgag
     6181 aagttatggc gtaactgaag attcactgcc ttactttaat caaaattact tccatattct
     6241 agagaagttg agaataaaaa taggagaata taaaatgaaa aaagtattaa ttattgtttc
     6301 tgttgttgta attgcacttg cagggattgg cattggagca tatttcttaa cacgtgaaaa
     6361 gtctccggag cagcaggttg tggggacttg gtacgatggt gaaaatgatg taacgattga
     6421 gttgaaatca aataagagcc tgaaaattac aaaagaaagt ggtgaatcta gaacaggtac
     6481 ttggcgaatt gcgggtgata aaattaagtt tacggcaaca agtggtccca aagctgaagg
     6541 tgaactttca acaggaaaga ttgaatctat tttctttgaa ttcactaaca ccaatgtaag
     6601 ttatgcactt cacgatgcca cctatgaaaa acaataaata gttataggac tcctatgaag
     6661 attcattgta ctcttcatag gagtcctatt ttgctgaata gtttttgcat gtggtgggta
     6721 atcaaatcaa aacatttagc ggaaataaac atattgaaag aacaggagaa tttaatatga
     6781 aaaaatggat actgatatcg cttttaagcc tgagtacttt gaccttggtt gcatgtggct
     6841 ctaatcaaat gaagcaggta acacagcaat catcttcgtc tagtaagcaa tcattaaaga
     6901 agaatagaca ggaatcattt caaacggtct tagatcgtta taaatcttat cagcaagcaa
     6961 taaatagtgg tgatgatagt cgtttaactg aagccttaaa acaggtcgaa gctacatctg
     7021 aggaatatat gctcattgat aatttagggc attcgggaac gtcagttgat tttcaatatg
     7081 cgttcgtaga cttagataaa gatggacatg acgagttatt gattggtaaa caagattata
     7141 tttctgcaat ttattatcta aaaaatagtc aacctacttt gttgcatgta gcttatgcag
     7201 cacctgttgg tggagcacgt tcatctctca ctgcttatga aaacggtcag gtggtatttg
     7261 ctgcctggca gtcatcgaat ccggaagtaa gcctaagttt atacaaagtt gaagctagtg
     7321 tcccaaataa ggaaaaagaa actacgatac aaatgaatga taagaagaaa atcgaagatg
     7381 aattaggtat ctcgtctacg gctttgaatc tcaaaaactt aaagtgggaa tcaattgata
     7441 aaggttcaat gacttcttca aaagaaagtg atatgaaatc ttctagtcaa agtgagaata
     7501 ttaagtcaga aactggtttt caggttcgtg tgcaaatatc ggatttggaa atacgcaaag
     7561 aaccgagagc taagtctcag tctctgggca agatatctca aggtattcac actattgcgg
     7621 aaacaacaaa tgcagaaggt tacacttggg ggagattaca atctggtcaa ggatggattg
     7681 ctcttgatta tacggaacga atagaaggtg agaaaaaaac tcaatcggaa tctagtggta
     7741 tgaacatcca agaaattcaa acaggtaatt tttcaagtgt taaaggatct tggagaaatg
     7801 aacaaggaaa tagtattact tttgatgcca atggcttgat tcaagttaat ggcaaacctg
     7861 cgggtgatgt agtttttgat aagttcgtcg taaaaggaga aaagctcaca gccgttacaa
     7921 aaacatcaga aggtattagt gagacaccaa ttgtatttac tccgtcggga caagatggaa
     7981 gagagtcaat tattctttcg atacacagaa gaccgcacag ctacttatta ctatctcttg
     8041 acagaagatg atagtcttgt ggccattgga gattttgata atagtaatca tcctgcacgt
     8101 ttctttttaa gtaacgatga atcgcatttt gatgagctgg ttgataccat gccaccttat
     8161 atgttgcctg gaatagaaga ggtgatctat gtaggtggtc gacaacagcg attggctaga
     8221 gaattgtatt gtgtcgcttg ccaggaacga gtcagtgagg atggtggggt acaatttggt
     8281 gaagtacttt taagtgagca taggcatgac gatcataaag cccttattta gtttctgata
     8341 ctgaagttat tcttgaatat aagaaaagca aaagcaccat tttaatttgg tgcttttttg
     8401 gtggagttaa actttttaaa agaaataatt ggaataatat aaatataggg atacttatta
     8461 tgctaattta attatttgat caaagtattt ttctctttct gaactaaggt gatgcgttac
     8521 ggtaatatag gtaatatcag tattttttaa aatattattt tcaataaaat cagaattagt
     8581 cttatcaaga tttgctgtag cttcatccat aataataatt ttactacctt ttaataatgc
     8641 tcttgcaata ccaattcttt gtttttgacc ttctgaaagt agatcattgg atacgctttc
     8701 ctttaaacgc cccagtaagt ctagtaaatt tacatctttc aaagcctttt taatttcatt
     8761 ttgtgtaatg tcttgagacc acagagttaa attattttca agtgtgtcat tgtaaatatg
     8821 tgtagaatta ctaatatatg cgacttgaga aacaatggaa ttttcatcaa tttcttttaa
     8881 ctctaaatta ttgtatttta catgacctgt ataattcttg agatttccta atataatatt
     8941 tatcaatgtt gactttccac ttccggattc accaataata gcatatttgt tattttttat
     9001 taagttgaga ttgagtttag agaagacttt tttattacca aaattgtatt ctaaatcgaa
     9061 aatatcaatt ttctcaatgt tatttactat ttttttctca gtatttttag aagaaatctc
     9121 aaattttaaa aataaaggtt taacagaatg aattgacact tgtagttgat tgagtgttgt
     9181 taatgaatta aaaatattac ctgaaatttg tcccacagaa gatatagaac caattgaaac
     9241 ttgtcctaaa gtgataagta aacctgtcaa gaaaagaatt gatacttgtg caatgataga
     9301 aaatgtagac atgattatct ctatcctagt actattttga gtgaatttta ctttttgtgt
     9361 tatatagttt ctaattattt ttgtggtctg aattaagaga gtaggttttt tactcgaata
     9421 ataaagtgtt ttgtatcctg ttaattggtc atttaatcca gatatgagct cttcgtttgc
     9481 agttgaaaaa agtgacataa aattttgcat ttttgtagca aatggtttag gaaggtatgt
     9541 aagacaaatt gttaatatta tagttaaaac tacaattcta atatcataac ttaaaagagc
     9601 aataatagaa aagatggtgg tgaataatgt agaaaataga ttatataaat ttgaaaagcc
     9661 actattttcg atgatttgaa tatcattatt taatatggag atatgatctc cgatagtttt
     9721 gctttggaat gtatggaaag aagcattagt tatgtttttg atataatcag aacgaatttt
     9781 tagagacatt tcttgtatta acttagcttg atggatatta atcatataag tgaatataag
     9841 atagagaagg tagagtgata tttcaattcc caaccaaata agaaagagtt taaaattacc
     9901 tgcgactaat tgatttgtca taaatgctaa ggtaacagaa gcacctacaa gaaatgcaga
     9961 attacaagca atgagaaata tatgtaataa atttttaaat ttaaattgta agatgtattt
    10021 tttcataatt tttgtccgta ttttgtacct tacttatcaa agagataaga gtttcaaaaa
    10081 aatagaattg gcctagcata ccatgagagt agctatactt tatttcatca catattggat
    10141 caattaatat aaatttacca tttttttcta ttgagtaatc acaaatgtga ttaacgatat
    10201 taatactagt ctctaaataa tgtattttat cgaaatagtg atataaccag gcattcgcta
    10261 gcccaagacc ggctaatcca ttatagagtg atgtactttt ggcataggga tgttctactc
    10321 ctttacctag ctttttaata aaatcatcat attctgtagt ttgttcagaa atactaaatt
    10381 ttattaattc aataattaaa cctgagtttc catttactag atatggtgaa agatagtctt
    10441 caataattag ataaggaaca tctttttcgt atttgatatt attagaaata atagatttta
    10501 ctagcttcct aaataaatta gttttttttt gttttgagtt taaaatggtt agtagacgat
    10561 atttttcttc gtattccaga tctttaaaaa agtcttcaga taacatatcg tcagataaat
    10621 tttcttgtga ttcatctagt aaaatttttg ctaactgaga atctaaatca ctcccttgaa
    10681 tatctctttt tgttattttt tcagacaaat taagacccaa ttgatttatt gctagatagt
    10741 tatctacttt ttcacaccaa gatttaccct ctatagaaat tgtagaacta gttaccagag
    10801 tatttaacag ttgatctcgt ttatatatga gtttttccaa atccattcct agtttgataa
    10861 agttaataaa aaatatttga ttgttccttt ctaacttaaa gtctttcata aatttattta
    10921 atagttgtaa agggaagttc atctctaaac atatctttgt aaatagcttt aaggtctctg
    10981 ttccagtctg atcaaatttt aaaagtgaac ttgcattggt tagtagattg atgatacagt
    11041 accataattt gactatatct ttatgttcaa attttgcata tatagttttt ggatagcagc
    11101 tatttgtagt tgctatcaac ggattttcat tttttaaata tgctgtttca aagtcaataa
    11161 aataaacttt gttttctggt gttagtatga tattactaca ggagatatcg tcaacaataa
    11221 caccatgatc atgaatatat tctaatgatt taaatagttt tgaaattatt tgtttgagtt
    11281 tattattgaa agttgtaatt tctgaaggag ttcgttttag gagcaaatta aagtctgttt
    11341 ttaaagtgtt aagtgtttta ccttcaataa attcctctac gaggtagtag ttatcttcta
    11401 aataaaaatc atcaatgtaa ttaggagtta ctgaacctga taatttttta attattttag
    11461 tttcgttttt tagtaattcc atagaagtaa tgtccctggt agcatagaca tatcttctag
    11521 cttcttttat aatcactttt ttagagttag taatatcaat tgcgatatag atatttcctg
    11581 caccagtttg ataaaggatg gacttcatat catatctctc atttaggata gtagaagtgt
    11641 tagttttttc aggaaagtat tcttttacaa atttagggca agaatagtat gcacctggta
    11701 aatctggata tgcaacacca ttattatcaa aaagacaggg tctttggccg ttttttacag
    11761 atgcattcat gagtccgtac ctataaaata taacctctga ctgtttataa ttttggtctg
    11821 tgattatttg gataccaggt tcatatttta tttcttgata taggacatcg agtagataca
    11881 gaaaggtttg atcgttttca gggtagatag taataaactt tccaatctca gtttgagagg
    11941 tcttttttga aaagataaat aataattttt ctatagagtt tataaattta aatggggtat
    12001 cgtttgttaa acagatagta gttacagaat ctaatatttt ttgataatta tctaatgttg
    12061 ctgaaatatg tatcttccag ccttggtatg ggatagattt attagttgaa aatacatagg
    12121 taaagttaga gttaataatt aagttatctg gggatagatt agttggaaaa atcatggtat
    12181 caatcataaa tattctcctt aaaaaaagct agaaccataa aaagatatta tctttttatg
    12241 gttctagctt acatcatttt aaacatcaaa gttagatatt gttatatagt ggaatctagt
    12301 agttcttcat agtaggcttc gtgagatacg agtagattat ttgctcctaa agttttgagg
    12361 actgaaaggc agttctcaat aagttttttt ccaatttcaa ctttacctga tttcatccag
    12421 aaagctccta aaagcatatt atactcaagt ttttcgtgta aaaagatttc tggaatacct
    12481 atatctgaaa ttatatctaa atacgacttt gctaaatcta gttgatttct ttcaataaat
    12541 tcagatgttg catttatcag taaatcaatc ctaattttta aatttgattc attatttcca
    12601 aaaagagttg ttctgtaaat gacttctttg acaagtacat tgagagtttc tgaagaaata
    12661 gctggcatac tatttcctag tattatcaac tccctcttac cccattgttc aatatcaaaa
    12721 agataatctg tgataatttt tattttatcc tcatctacat cttcctctgt aattgtagat
    12781 aaaaaggatt caatcatgat tgtattatac aggaatagtt ttttattgct atcatgatat
    12841 tttttattct cttcttttag gtattttttt aaagcaagta tattattttg ataatacgcc
    12901 ttactaacac gttctaacag tagttctgta taagtcggtt tttcttttga gagaatacca
    12961 tagaattctt ctatactaac atctagattt tctagtagta agaagaaccg agataaagaa
    13021 atttctgatt ctccacgctc aaattttgac aagaaagata tcgataagta gtcaccagca
    13081 acgtctttta aagctaattt ttttgacaag cgaatctttt tgaatagtgc gcccatttct
    13141 gtggtttcaa tcatagaact tctctcaata gataaaattt taataaatta tatcaaaata
    13201 ataaaaaaaa gtaaaaaggc gtatgtttag tgaacatagc cttcttactt ttaagatgtt
    13261 gcgatagggc aaaagatggt aagaataggt cttccttgtg tggtaattgt ttctttagga
    13321 agttggttaa gttgttgtac gttcatattg atctccttta agatgttgcg atagggcaaa
    13381 agatggtaag aataggtctc ccttgtgtgg taattgtttc tttaggaagt tggttaagtt
    13441 gttgtacgtt catattgatc tcctttaaga tgttgcgata gggcaaaaga nnnnnnnnnn
    13501 ccagtcgaag agcaagccac ccgttctcac gggtggtttt gactgtgctt ctatttagat
    13561 ttttttcggc atagtattga cagtagtcta tgataagcgt agaatctttt tcaaataaag
    13621 aatataggtg tgcttaccaa gatagcattt ctttccgaat ttgatgatag tataaatcaa
    13681 atgtttacct tgagaaaagc aggacctatt tagggagtgt tccagatgac aaaaagcaat
    13741 aacacccaaa ttgatgatat catgaacaat atctataatc ttattttaaa tccagaaaca
    13801 actgaaaatg agagaaagtt actcgtaacg tttaaaaatg aaattgaagt tggaaagaag
    13861 gatagtagtg aacttcttgc agagttacgc agagctattc aagttctagc agtcgagaat
    13921 cttcctaaag gaatttcatt aagttatgga gtgagtgagt tgagtaagac tctcgcagaa
    13981 ttccaagatg aatcagaacg caacattaat ctagcaagag gattgtcatc aatcgccatg
    14041 tcttttagat gatttatctg tttgtgatga ttaataatta aaatgacaaa aaagatcaac
    14101 tgaattgaac cgactaagtt gtattctgtt ttttgctatt gattacttaa ttgaggtatc
    14161 aaaaaatcca ctggtataca aaaccaatgg atttcaacaa tttatttttt cttccctagt
    14221 acaaaataat ggctagggat ttgttgtgtc aaactgactg cgatggcgat ggtaaatgag
    14281 gctaggaaac aagctcgtag gaagttgagg cctaggtctg catttccaat caataggaag
    14341 tagatggcac ggtagaagct cattcctgga atgagtggga acatgcttga ggctaggaag
    14401 acggtagctg gacatctacg gtagtgggcc aagaaacgtg aggtgaaagt gaccagtaag
    14461 gcaggaaaga ggatggctaa aacttcgtgg tgggtattat tccaaatcaa gaggtagagg
    14521 agccatgagc cagcacctag tgttccaagg tctaaaaagt atttcttagg tactcggtat
    14581 agcacggaga aggctgctgt tcctagtcct gccatgacag tctgaatcaa gacctcctgc
    14641 catgaggtag ttggtgttga gaacatacct gataattgtt ccgcaaaggg gagaagggaa
    14701 atcatggcaa gaacaccgac agagatagac agacaagtgg agacccctga cagcatcagg
    14761 gccagaccac tataatagtt gttctgggtg aattcacgga tagcattaac aaagtaggct
    14821 ccaggaatca aaatcatcag ggctcctagg atgataacgc tacgatgttg cccgataccc
    14881 agataataga gaatattagc tgatagagcg gcaatggcac tagagagaat aatctgcaaa
    14941 aaactagtat gaataaaacg ggaaaaaagc tgcataccaa tccccacaaa aagtcccgat
    15001 atagccgcag cagtaccatc aatcaagcca cttccaagag ctagcgagaa gctcccagca
    15061 ccaatgacac aggctataat atcctctaaa ggacgataga aagtcttctg ctcaatggtt
    15121 ttcagctttt ggaaaatgct agaaacgggc tgatttggct gttctgccag ttcacgagac
    15181 aggcggttaa cctcctctag ttttcctaga tgaatagaag ggactgaggt agctagaaca
    15241 cgagactcct taagacctga gcggttgagt ccggaaatca taactcctcg attgaccacg
    15301 taagtggaga agtctctgat gccaagagac ttggccatat gacccatggt gtcttcgata
    15361 cggtaaatct cggcaccgct ctccataaga actcgccctg cctgaaggat ggcatccatt
    15421 tcgttttgcg tctctgtttc atttggaaaa tcgatagtca tgtaaccgct ccttatcgct
    15481 ttagtagcca tttcattata agctttgaga agccgttttt caatgacttt ggtgactaaa
    15541 gtgagtcttt ttatgagatt tttcttctac ttaataatat attttaggaa aatgacggtc
    15601 ttccttttta acttgccacg gctggaggca agtgctacaa ttgaattata aattgtatgc
    15661 gtttacacat tgttgctttt cctcttctaa aatgattgaa aacctgtatt tataagggaa
    15721 aattgatttg agatggaagt acattgaagt gtaaatagat gatccctttg aaaaggagga
    15781 aattccatga aaaaaattat caataaacct gaaaatattg ttactgagat gttagatggc
    15841 ttggcttatg ttcacaatga tctggttcat agagttgaag gttttgatat cattgcaaga
    15901 aatgagcagg ttgctggtca ggtaggtctt atttctggtg gtggaagtgg tcatgagcca
    15961 gctcatgctg gttttgtagg tgatggtatg ctttcggcag ccatcgcagg tgcagtattc
    16021 acatcaccaa cgcctgatca aattttggaa gcaatcaagg aagcggacca gggagccggt
    16081 gtcttcatgg ttgttaaaaa ttactctggc gacatcatga atttcgagat ggctcaagaa
    16141 ttggctgaga tggaaggtat cgaggttgct agtgttgttg tggacgacga tattgctgtg
    16201 gaaaatagcc tctatacaca aggtcgtcgc ggggttgctg gtactatttt tgttcacaaa
    16261 atcctaggtc atgcggctcg tgaaggtaag tctctggctg aaatcaaaga tttggctgac
    16321 aagattgttc ctaatattca caccattggt ttggccctta gcggtgcgac ggttcctgag
    16381 gttggtaagc ctggttttgt tctagctgag gatgaaattg aatatggtat tggtattcat
    16441 ggtgagccag gctatcgtaa ggagtctatg cagccatctc gccagttagc agaagaatta
    16501 actggtaagc ttcttgaatc ctttgatgct aagtctggtg atcgctatgc tcttctcatc
    16561 aatggtatgg gggcaacgcc actcatggag caatatgtct ttgccaatga tgttgcaagt
    16621 cttcttagag acgcgggtct agaagtgatc tatagaaaac taggaaacta catgacttct
    16681 attgatatgg caggtctttc actaactctt atgaagattg aagatgacgc ttggcttgag
    16741 gctctagaaa gtcctgttaa gactatcgca tggtaagaat gacaaaaact agaaatcggg
    16801 tatattatgg ataaaatagt tgcagtaaaa tggatgcaag tctttaatca aaaagttgaa
    16861 gcagaaaaag atcacttatc tgagttagat ggtcctatcg gagatggtga tcacggggct
    16921 aacttggcgc gtggtatggc agcagccgtt gaagctatta acacatcaga ccctcaaagt
    16981 acggcagatg ttctaaagac ggtatcaatg gctctgataa gcaaggttgg tggggcttct
    17041 ggtccgctct atggctctgc ctttatgggg atgatgaagg ctgagcaggc tggtcaagat
    17101 ttagcaggtg tccttgaggc aggtgccgat atgattgaaa aacgaggcca tgctcaagtt
    17161 ggcgaaaaaa ccatgattga tgtctggcgc ccagttattg aagcagttaa acgagatcaa
    17221 ttaacgaatg aagtcatcga tcaagcagtt ctttcaacga aggatgttgt tgctaccaag
    17281 ggacgtgcct cttatgtagg tgagcgttct attggtcaca ttgacccagg ctcttattcg
    17341 tctgggctac tcttcaaagc cttgctagaa gcggagggct aggacatgtc ggaacttgga
    17401 attgtgattg tatcccactc cgctgatatt gccaagggat tggtgagtct gattcgtgaa
    17461 gttgcaccaa atattccttt gacagctaca ggcggtcttg aagatggtgg actgggatct
    17521 agttttgacc atgttcaagt agcagtagat agtcagcctg ctaaacgtct cttggccttt
    17581 tacgatttag gcagtgcacg catgaatttg gagatggttg aggaattttc agaaaaggat
    17641 attctcattc aacatgtccc ccttattgag ggggcctaca cggcttcagc ccttcttcaa
    17701 gcaggagcga gtgaggttga aatcttatct caggtaaatg aattaaccat tcaaaaataa
    17761 agaaagttac actatggaaa atcaaatcaa gtataggtgg gccagtcttg ggactggtgt
    17821 tatcgcaaat gagttggcac aggctttaga ggccctaggt ggtaaactct attccgttgc
    17881 aaatcgtacc tatgacaagg gagtggcctt tgctgagaaa tatggaatcg aaaaggttta
    17941 taaagagatt gatcaagtct ttgaagaccc tgaagtggat attatctaca tttcaacgcc
    18001 tcacaatacg catatcaatt ttcttcgcaa ggcactcgca gcgggcaaac atgtcctctg
    18061 tgaaaaatct atcaccttaa acagtgaaga attggcagaa gctatccaac tcgccgaaga
    18121 aaaccatgtc aaactggcag aagccatgac cattttccat atgcctatct atcgaagact
    18181 ctctgaaatc gtggaaagtg gtaagctagg gcctctcaag gttatccaga tgaactttgg
    18241 ttcctataaa gaatatgaca tgaccaaccg cttttttaat cgtaacttgg ctggtggagc
    18301 tttgcttgat atcggtgtct atgctctttc ctttgtacgt tggtttatga cgtcacaacc
    18361 gacagaaatg gtttcacagg ttaaattagc tccgactggt gttgatgagc aagcgggcat
    18421 tctccttacc aatgcagaag gagaaatggc gacggtgacg ctaagtcttc atgccaaaca
    18481 acctaaacgt ggcaccattg cttatgataa gggttatatc gaaatttacg agtatccacg
    18541 tgggcaaaag gcagtcatca cctatacgga agatggctca caagaagtca tcgaagtagg
    18601 tgaaactgcc aaagcactcc agtatgaagt tctagacatg gaagcagccg tctcaggtca
    18661 agaaaatcat ctttatctca actatagcca agatgttatg gagctcatga cgcgactccg
    18721 caaagattgg ggcttggtct acccagaaga agagtagctt accgactcac tcaaaaagac
    18781 tcagtttttg ctgagtcttt ttaacttatt taaaactaaa cccctcataa acgagctcag
    18841 cctttggatt gtttgccgta aaggttttag caaatgcttc catcattttc actggaccac
    18901 acataaagac agttgtgtca tcagtgagag gatagtcagt gaagtccaga taaccatcca
    18961 cttgactatt aatagtgtga agcttgaaat ttctattttt tgcagcatat gcagccaaca
    19021 tctccagata gacagcgttt tgctcacctg tataggcgta gtagaagtcg acatccctat
    19081 caaggacagg attttcacgg atataggaaa tgaaaggggt gatgccgata ccacctgcaa
    19141 tccaaacttg tttgtcacga ccttgatcta gcaacatgtg accataggca cggtcgatag
    19201 ctactgggct tccgactctg agcttcttgt agatttgttt ggtatgatca cctgaagcct
    19261 taacggtaaa atagataata ttgccatgtc cacctgagat agagaaaggg tgaggtgcct
    19321 tctcaaaacc agcttgaagt atcttaataa aggtaaattg accaaattga taatccattg
    19381 gacgtgttag cctaatagct atttctgttg tgtcatggtt aatacgtttt aagcccacaa
    19441 ttttcccacg atttttaaag ccgaaaattt ggtagaggaa gatgatataa aaacctgaac
    19501 ttaaaccaag gatagcgaag ccccccacta ccaaggataa gagatttagc ttagtcaata
    19561 cgtgtcccaa aatcaagtag acatgggaga gaccaaaaat ataggctaag tataccaaac
    19621 gatgaagcca acgccaagtt tcatatttga gagttttgcc aagaaagacc agaaccacaa
    19681 tagccaagaa agtataaata ccaaggtttc ctaactgagc agccagacgg gaaccccata
    19741 gactccccat accgatgttg tggaaaacaa ggagaacaac tgataagatg gcaagaaatt
    19801 tgtggacagc gtacattctt tcaattccgt taaagagttt ttctaaaact cgtgatcgtg
    19861 ttgccaacat aaaagtccat gataaggttg ttaaagctag accaggagcg atgaagtttg
    19921 tcatgcccct tgctagccag gcgtagaccg tcagaacaat acttacggtt agtagaagaa
    19981 ttcctttata tgatttcaca taaccttctt tctattattt ccattatcgc caattagttg
    20041 taacagatat cattacatta tatcttataa tagattttct gtcaaaaata attaattttt
    20101 tgaaaaaaag ctgatagtga tatagtaatc aaggtatgca atactttttg aaaaggcaca
    20161 atgattgtca agaaacgttg atttaatagt cgattatctt gtgaaagcgt ttctaaaagt
    20221 gtatactata agtagaagat aggaagaggg aatgcttagt ggctagtatt agaatagaag
    20281 ctagtaaggt ggctagaaag agtcccattc gagtagacac tagtcttgtc ggggcggttt
    20341 ctggtgtgga agcagtaact gtttacctac cgtcatcaaa ggctcgtttg agtgttggta
    20401 aattgggtta caagtccaat actattactg tggaggatgg acagaccgtt cgggttacta
    20461 gcaattttct aaatcgtttc atagcgatag ctccattgtt tctctacctt tttggaggtc
    20521 gttacctctc gcttgttgct gccctatcta ctataatttt gctttttagc ttaccttttc
    20581 tcaagttaga aatcgtaggc tgattagaat cgggggtggc ttagccctct gtttgattcc
    20641 tttaactcat tttttcataa taatgctagg ccactccctt tttattagga acgggttgag
    20701 acgaaaaatt agttatcaaa aagggaactc gatagagttt cccttttttc tttatcaagc
    20761 taaagtcatt tttaaaagac cccagttact aaaactgagg tctttgatgt ttatagtcag
    20821 ttatcactta cggtacaatt tgtcgtattg atagtaagga tcgaaggtca cattgatacc
    20881 aagcttacgg agaacatttt tatcttcatc agtaaggatt atagttgagt gagcttcaga
    20941 acccttaagg ttaccaagtt cctccatggc acgtgccgca tccgtattgt tggcagctgt
    21001 aatggccaag gcaatgagga tttcgttaga gtggagacga ggattacgac tacccagatg
    21061 gtcaattttc agaccttgta taggtttaac cacttcaggt tcgataagtt tagtatcctt
    21121 atcaatacct gcagaagttt tgatagcatt aatcaaagca gccgcagttg gaccaaagag
    21181 ttctgaattt ttaccagtga cgatttgacc attcggcaac tcaagcgcaa gagcagaacc
    21241 acctgtttct tcagccttag cacgtgctgc aacgaccact tgacgatctt caggagtgat
    21301 gccaagatcg ttcatgagta attcaatctt cttaatagca gactcaggga cacgttcatt
    21361 tttgaaatca agcacggttt gatagtagcg acggatgatt tcttgtttgg aagcttcttt
    21421 ggctgcctca tcatctgtaa tggcaaaacc aaccatgttt acacccatat ctgtaggtga
    21481 agcgtaaggt gactcaccaa gaattcgttc aagcatacgt ttaaggactg ggaaaatctc
    21541 gatgtcacgg ttgtagttta ctgtagtttt gccataagtt tccaagtgga aggggtcaat
    21601 catattgaca tcatcaaggt ctgcagtggc agcttcatag gccaagttaa ctgggtgatg
    21661 aagtggcaga ttccaaactg ggaaggtttc aaatttagca taacctgact tgataccatt
    21721 gatttggtcg tggtacatgt tagacataca tgtcgccaat ttaccagaac caggaccagg
    21781 agcagtaacg acgataaggt tacggctagt cttgatatag tcgtttcttc ccataccttc
    21841 gggagagata atatggttca tatccgttgg atagcccttg atagggtagt ggatgtaaga
    21901 cgtgatgcca tttttttcaa gttggttacg gaaggcatca gccgtaggtt gacctgaata
    21961 ctgcgtaata acaacagaac ccacatagat attgagctcg ttgaatttat caatcagacg
    22021 aaggacctct tgatcgtagg aaatgccaag gtcaccacga gccttagaat gctcgatatt
    22081 gctagcattg atggcgataa ccacttcgac ttgctcttta agctcttgaa ggagcttgat
    22141 tttattgtca ggttcataac caggaaggac gcgggcagcg tggaaat
//
