LOCUS       c00005_NZ_LXZX..        7667 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_LXZX01000005.1 Streptococcus vestibularis strain 22-06 S6
            SAS601000005, whole genome shotgun sequence.
ACCESSION   NZ_LXZX01000005
VERSION     NZ_LXZX01000005
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 14:07:28
            Original ID  :: NZ_LXZX01000005.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 167579
            Orig. end    :: 175246
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..528
                     /locus_tag="ctg5_174"
                     /transl_table=11
                     /translation="MFQLKTWVDKDGELTPKGRKLSRVLVCAYLLCLVLLCWTPQYGLV
                     EGVETPGIQHFGRVVVLLTPFNSLTNFYQLDSLKEIVFVLGQNVTNIFLLSPLILGLLA
                     LYPRFRSWKKVLLATFVMSLTIEVGQVILDLLIDANRVFELDDLWTNTLGGLVALGVYR
                     LLVKLIQTHSKE"
     protocluster    1..7667
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[172364:172544](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4786..4965
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..7667
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..7667
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     PFAM_domain     79..495
                     /aSDomain="VanZ"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04892.14"
                     /description="VanZ like family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg5_174_0001"
                     /evalue="1.50E-18"
                     /label="ctg5_174"
                     /locus_tag="ctg5_174"
                     /protein_end="165"
                     /protein_start="26"
                     /score="67.8"
                     /tool="antismash"
                     /translation="CAYLLCLVLLCWTPQYGLVEGVETPGIQHFGRVVVLLTPFNSLTN
                     FYQLDSLKEIVFVLGQNVTNIFLLSPLILGLLALYPRFRSWKKVLLATFVMSLTIEVGQ
                     VILDLLIDANRVFELDDLWTNTLGGLVALGVYRLL"
     CDS             630..755
                     /locus_tag="ctg5_175"
                     /transl_table=11
                     /translation="MKHLMMTVVTVLTLGVTMTMVKADTYQSGRDADIMRERGQV"
     CDS             947..1081
                     /locus_tag="ctg5_176"
                     /transl_table=11
                     /translation="MDGGYKVYNFDSFAYQLPESTDFGKLSYIGHFQLEDGTIYRYWK"
     CDS             1131..2888
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 378.6; E-value:
                     9.1e-115)"
                     /gene_kind="transport"
                     /locus_tag="ctg5_177"
                     /transl_table=11
                     /translation="LFFKESIIAKLWWFFKLEKRRYIIGILALSLVSVLNLIPPMVMGR
                     VIDAITSGKLTNQMMLLNLVYLLLAALGMYYLRYVWRMYILATSYRLGQIMRSRLFEHF
                     TKMSPSFYQKYRTGDLMAHATNDINSLTRLAGGGVMSAVDASITALVTLITMFFSISWQ
                     MTLVAVLPLPFMAFATSRLGRKTHKAFGESQVAFSELNNKVQESVSGIKVTKSFGYQEA
                     ELQSFQETNKMTFKKNMHTMKYDSLFDPLVLLFVGSSYVLTLLVGAFMIQANQITVGNL
                     VTFITYLDMLVWPLMAIGFLFNITQRGNVSYQRIENLLEQESDVQDPAHPLPSIENGCL
                     EYAIDRFTFEDEDTLRDIHFTLDKGQTLGLVGQTGSGKTALVKLLLREHDVNQGAIYLN
                     GHDIRDYRLSDLRSLMGYVPQDQFLFASSILDNVRFGNPDLAFEKVEVATKLAQVYDDI
                     KAMPEGFETIIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEHAIIDN
                     LKHTRKDKTTIITAHRLSAVVHADLILVMQDGRIIERGCHDDLLAQDGWYAKTYESQQL
                     EMEGGEARA"
     PFAM_domain     1197..2015
                     /aSDomain="ABC_membrane"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00664.25"
                     /description="ABC transporter transmembrane region"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg5_177_0002"
                     /evalue="1.40E-40"
                     /label="ctg5_177"
                     /locus_tag="ctg5_177"
                     /protein_end="295"
                     /protein_start="22"
                     /score="139.8"
                     /tool="antismash"
                     /translation="IIGILALSLVSVLNLIPPMVMGRVIDAITSGKLTNQMMLLNLVYL
                     LLAALGMYYLRYVWRMYILATSYRLGQIMRSRLFEHFTKMSPSFYQKYRTGDLMAHATN
                     DINSLTRLAGGGVMSAVDASITALVTLITMFFSISWQMTLVAVLPLPFMAFATSRLGRK
                     THKAFGESQVAFSELNNKVQESVSGIKVTKSFGYQEAELQSFQETNKMTFKKNMHTMKY
                     DSLFDPLVLLFVGSSYVLTLLVGAFMIQANQITVGNLVTFITYLDMLVWPL"
     PFAM_domain     2193..2636
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg5_177_0003"
                     /evalue="5.70E-28"
                     /label="ctg5_177"
                     /locus_tag="ctg5_177"
                     /protein_end="502"
                     /protein_start="354"
                     /score="98.2"
                     /tool="antismash"
                     /translation="LRDIHFTLDKGQTLGLVGQTGSGKTALVKLLLREHDVNQGAIYLN
                     GHDIRDYRLSDLRSLMGYVPQDQFLFASSILDNVRFGNPDLAFEKVEVATKLAQVYDDI
                     KAMPEGFETIIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDS"
     CDS             2881..4626
                     /gene_functions="resistance (resist) ABC_efflux (Score:
                     269.9; E-value: 2.7e-82)"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 305.9; E-value:
                     9.3e-93)"
                     /gene_kind="transport"
                     /locus_tag="ctg5_178"
                     /transl_table=11
                     /translation="VPNQNQWSVFKRLLTYLKPYKLLTFLALTFLLSTTVIKSVIPLVA
                     SYFIDHYLQDLNQAASMILIGYYGLYLLQTLAQYLGNLFFARVSYSIVRDIRRDAFANM
                     EKLGMSYFDKTPAGSIVSRLTNDTETISEMFSGILSSFISAIFIFVTTLYTMMILDIRL
                     TGLIVLFLPLIVLLVNLYRKKSVVIIEKTRALLSDINAKLSESIEGIRIIQAFNQEKRL
                     KKEFDVINEEHLIYASRSMSLDSLFLRPAMSLLKLLGYAVLMAYFGYRGIYLGITAGTM
                     YAFIQYINRLFDPLIEVIQNFSTLQTSMVSAGRVFALIDERTYEPEQRDTDAKVTEGNI
                     RFENVSFSYDGKHQILDNISFSVNKGETIAFVGSTGSGKSSIINVFMRFYEFQSGRVLL
                     DGVDIRDYSQAELRKNIGLVLQEPFLYHGTIKSNIAMYQDLTDEEIKAAAEFVDANHFI
                     DKLPEGYDAPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANIDSETEAIVQNS
                     LAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGCIIEHGSHEELLDLGGTYHKMYSLQAG
                     VMEGA"
     PFAM_domain     2953..3762
                     /aSDomain="ABC_membrane"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00664.25"
                     /description="ABC transporter transmembrane region"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg5_178_0004"
                     /evalue="2.80E-39"
                     /label="ctg5_178"
                     /locus_tag="ctg5_178"
                     /protein_end="294"
                     /protein_start="24"
                     /score="135.5"
                     /tool="antismash"
                     /translation="FLALTFLLSTTVIKSVIPLVASYFIDHYLQDLNQAASMILIGYYG
                     LYLLQTLAQYLGNLFFARVSYSIVRDIRRDAFANMEKLGMSYFDKTPAGSIVSRLTNDT
                     ETISEMFSGILSSFISAIFIFVTTLYTMMILDIRLTGLIVLFLPLIVLLVNLYRKKSVV
                     IIEKTRALLSDINAKLSESIEGIRIIQAFNQEKRLKKEFDVINEEHLIYASRSMSLDSL
                     FLRPAMSLLKLLGYAVLMAYFGYRGIYLGITAGTMYAFIQYINRLFDP"
     PFAM_domain     3946..4392
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg5_178_0005"
                     /evalue="7.80E-32"
                     /label="ctg5_178"
                     /locus_tag="ctg5_178"
                     /protein_end="504"
                     /protein_start="355"
                     /score="110.7"
                     /tool="antismash"
                     /translation="LDNISFSVNKGETIAFVGSTGSGKSSIINVFMRFYEFQSGRVLLD
                     GVDIRDYSQAELRKNIGLVLQEPFLYHGTIKSNIAMYQDLTDEEIKAAAEFVDANHFID
                     KLPEGYDAPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATA"
     CDS             4786..4965
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_179"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 4.6e-11,
                     bitscore: 39.7, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRQTNNNFELLDLESLTNVEGGGWVKCYAGTIGSALVGSAGGPV
                     GYWGGALVGYATFC"
     PFAM_domain     4807..4947
                     /aSDomain="Bacteriocin_IIc"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10439.11"
                     /description="Bacteriocin class II with double-glycine
                     leader peptide"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg5_179_0006"
                     /evalue="1.60E-09"
                     /label="ctg5_179"
                     /locus_tag="ctg5_179"
                     /protein_end="54"
                     /protein_start="7"
                     /score="37.7"
                     /tool="antismash"
                     /translation="NFELLDLESLTNVEGGGWVKCYAGTIGSALVGSAGGPVGYWGGAL
                     VG"
     CDS             4981..5148
                     /locus_tag="ctg5_180"
                     /transl_table=11
                     /translation="MFKDKKMYLLAIFLLGFGIANLFRNLDFVHHIINLVGLTLITYSL
                     IFSKWERLKK"
     PFAM_domain     5288..5362
                     /aSDomain="ComC"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03047.16"
                     /description="COMC family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg5_181_0007"
                     /evalue="1.70E-04"
                     /label="ctg5_181"
                     /locus_tag="ctg5_181"
                     /protein_end="25"
                     /protein_start="0"
                     /score="21.3"
                     /tool="antismash"
                     /translation="MTRQTNNNFELLDLEALANVEGGDG"
     CDS             5288..5377
                     /locus_tag="ctg5_181"
                     /transl_table=11
                     /translation="MTRQTNNNFELLDLEALANVEGGDGLCLI"
     CDS             5365..5490
                     /locus_tag="ctg5_182"
                     /transl_table=11
                     /translation="MFDLKSYILGMVCMALMTFLDKPIMSFLEKHKATNSVNKKS"
     CDS             5848..6015
                     /locus_tag="ctg5_183"
                     /transl_table=11
                     /translation="MFKNSKPYLLATILIGMGLANLFRSLDAVHHTINLLGLTVLLYSL
                     LFKKWVQFQK"
     CDS             6345..6746
                     /locus_tag="ctg5_184"
                     /transl_table=11
                     /translation="MKLKNISSSVLRSFRTITAALAVFLISISLSLYKSKISPGTWLAV
                     GALALVVIFVNGLLYRMLKKRPDSVNLLTIRQSFIVFLVISFLVLCVEFYTLLTFSDTT
                     DRIMLVVLMLLLILCDFLAYLQVKKYFKK"
     CDS             7287..7667
                     /locus_tag="ctg5_185"
                     /transl_table=11
                     /translation="MSKNLRALTAIVLSQLLIEWVGFFLGIPLSKILVLTVLSSLVEIL
                     MHLILSKKSKVTLGDKEIGHQYFLFFKKTLWLSILFVAIFLFYTIIKSDSFMLYFYWHI
                     FVLFHCLGYIICLNNIKINRKN"
ORIGIN
        1 atgtttcagc ttaagacttg ggtagataag gatggagaac taacaccaaa aggaagaaag
       61 ctaagccgag ttttggtctg tgcttatctc ctttgtttag tactcctatg ctggacaccc
      121 cagtacgggc tagttgaagg tgttgaaacc cctggtattc aacattttgg tcgtgtcgtg
      181 gtcctattaa ccccattcaa tagtttgacc aacttttatc agctggatag tcttaaagag
      241 attgtctttg tgcttgggca aaatgtgacc aatattttct tactgagtcc gctgatttta
      301 gggcttttag ccttgtaccc cagattcagg tcttggaaaa aggttctttt agcgaccttt
      361 gtcatgtctt tgacgattga ggttggacaa gttatcctag atcttctcat tgatgctaat
      421 cgtgtctttg agttagatga tttatggacc aacactttgg gaggtttggt ggcactaggt
      481 gtctaccgcc ttcttgtaaa actgattcaa acgcattcta aagagtaaaa aacctgggag
      541 cttacgcgtc tcaggtttca cttattttct atcatacaaa tacaacacat tcaaaagagg
      601 gaaaatgaat aaacacgttt ggagaaataa tgaaacattt aatgatgaca gtagtcaccg
      661 tattaacgtt aggagtaaca atgacgatgg ttaaggcaga tacttatcaa agtggtcgtg
      721 atgccgatat catgcgagaa agaggacagg tttgaaatta ttctgaggct aagagaaagc
      781 ttcaattagc caactacaat accgatggtc gctatctcag tgaggcaact aactttgaat
      841 tgtacaattt tgtcatagag tataatataa gacttctgat gaaatcagac acatttggag
      901 ccctaagaag gatgcgtcag tcattcgtga caaggagaga tactctatgg atggtgggta
      961 caaggtctat aattttgact cctttgctta tcaattgcca gagtctactg attttgggaa
     1021 gttatcttat attggtcact ttcagttaga agatggcaca atctatcgct attggaagta
     1081 accttttgtt agaattataa tcactcgttt gtaaggatag gggtaataac ttgtttttta
     1141 aagaatcaat cattgcaaaa ctttggtggt ttttcaagtt ggaaaaacgc cggtatatta
     1201 ttgggatttt agcactgagt ctggtttcgg ttctcaatct gattcctcct atggttatgg
     1261 ggagggtcat tgatgctatc acatcgggaa aattgaccaa tcagatgatg cttctgaatc
     1321 tcgtatattt gctattggca gctttgggga tgtactattt gcgttatgtt tggcgcatgt
     1381 acatcttggc gacttcttat cgcttaggcc agattatgcg ttcacgccta tttgagcatt
     1441 ttaccaagat gtcgccttct ttttatcaaa agtaccgaac tggagacctc atggcccatg
     1501 caaccaatga tatcaactct ttaacccgct tagctggtgg gggtgtcatg tcagccgtag
     1561 atgcctctat cacagctttg gtaaccctaa tcaccatgtt tttcagcatt tcctggcaga
     1621 tgacactggt ggctgtctta cccctaccct tcatggcttt tgcgaccagt cgtttgggcc
     1681 gtaagaccca taaagctttt ggagaatctc aggtagcctt ttccgaactt aataataagg
     1741 ttcaagagtc ggtatcagga atcaaggtaa ccaagtcttt tggctatcag gaggctgagc
     1801 ttcagtcctt ccaagagacc aataagatga cctttaaaaa gaatatgcat actatgaagt
     1861 atgacagcct ttttgatccc ttggtcttac tctttgttgg ttcatcttat gttttgaccc
     1921 ttcttgtcgg tgcctttatg attcaggcta atcagataac ggtcggaaat ttggtaacct
     1981 tcattaccta tttggacatg ctggtttggc ctctgatggc cattggcttc ctctttaata
     2041 tcacacagag gggaaatgtg tcctaccaac gtattgaaaa tcttctggag caggaatcag
     2101 atgttcaaga tcctgcgcat cctctcccaa gtattgaaaa tggttgctta gaatatgcga
     2161 ttgaccgctt tacctttgag gatgaggata ctttgagaga tattcatttc accttggaca
     2221 aggggcaaac ccttggcttg gttgggcaga ctggttcagg aaagacggct cttgtcaagt
     2281 tgctcttgcg ggagcacgat gtaaatcaag gagccatcta tttgaatggg catgacatcc
     2341 gagactatcg cctgtcagac ttgcgtagct tgatgggcta tgttcctcaa gaccagtttc
     2401 tctttgccag ttccatttta gacaatgtcc gctttggtaa tcctgatctt gcctttgaaa
     2461 aggtggaagt agcgactaag ttggctcaag tttatgatga catcaaggct atgcctgaag
     2521 gctttgaaac gatcattggt gaaaagggtg tcagcctatc aggtggtcaa aagcaacgtc
     2581 tggccatgag tcgtgccatg attttggatc cagatatttt gattttggac gactccctat
     2641 cggcagtgga cgccaagaca gaacatgcca ttattgataa tctcaagcat actcgtaagg
     2701 acaagacaac tatcattact gcccaccgtc tgagtgcggt ggtgcacgct gacctcatcc
     2761 tagtcatgca ggatggtcgc atcattgaac gtggctgtca tgatgactta ctagctcaag
     2821 atggttggta tgccaagacc tatgagtctc aacagttaga aatggaagga ggagaagctc
     2881 gtgcctaatc aaaaccaatg gtctgtgttt aagcgtcttt tgacttatct caagccttac
     2941 aagttattga cctttttagc tttgaccttc ctcttgtcca caacggttat caagagtgtc
     3001 attcccctgg tggcctccta ttttattgat cactacctcc aggatttgaa tcaggcggca
     3061 agtatgattc tgattggata ctatggtctc tacctcttgc agacactggc ccagtatctg
     3121 ggaaatctct tctttgcgcg tgtgtcctac agtattgtca gagatattcg tcgagatgcc
     3181 tttgccaata tggaaaaact gggcatgtct tactttgaca aaactccagc aggctctatc
     3241 gtttcccgct tgaccaatga tactgaaacc attagcgaga tgttctcagg aattctctct
     3301 agctttattt cggctatctt tatctttgtc acgacccttt ataccatgat gattttggac
     3361 attcgtctga ctgggcttat tgtgctcttt cttcctttga ttgtcctttt ggttaacctc
     3421 taccgcaaaa aatcagtggt catcattgaa aagaccagag ccttgctttc agatataaat
     3481 gccaaattgt cagagagtat cgaagggatt cgcatcattc aggcctttaa ccaagagaag
     3541 cgtctcaaaa aagagtttga tgttattaat gaggaacacc tgatttatgc cagccgttcc
     3601 atgtcactgg attctctctt tctacgccca gccatgagtt tactgaagct gctgggttat
     3661 gctgttctta tggcctattt tggctaccga ggtatctatc tgggaatcac agcaggaacc
     3721 atgtatgcct ttatccagta tattaatcgc ctctttgatc ccttgattga agtgatacaa
     3781 aacttctcaa ccctgcaaac ctcgatggtc tcagccggtc gggtctttgc cttgattgac
     3841 gagcgtacct atgagcctga acagagagac acagacgcca aggttacaga gggaaatatt
     3901 cgctttgaaa atgtctcctt ctcttatgac ggtaagcacc agattttaga taatatttcc
     3961 ttctctgtca ataaaggtga aaccatcgct tttgtcggtt ccacaggttc tggaaaatcc
     4021 tctattatca acgtattcat gcgtttttat gagttccaat caggacgagt tcttcttgac
     4081 ggtgtagata ttcgcgatta tagtcaggca gagctgcgta agaacattgg tcttgtcctt
     4141 caggaaccct ttctctatca tggtacaatc aaatccaata ttgccatgta tcaggattta
     4201 accgatgaag agattaaagc cgctgctgag tttgtggatg ccaatcactt tattgataaa
     4261 cttccagaag gctatgatgc tccagtttct gaacgaggtt caagtttttc aaccggtcaa
     4321 cgccagcttc tagcctttgc tagaaccgtt gctagccagc ctaaaatctt gattctggat
     4381 gaagcgacag ccaatattga ttcggagaca gaggctattg tccaaaactc tctagcaaaa
     4441 atgcgtcaag gacgcacaac cattgctatt gcccaccgcc tatcaacgat tcaagatgcc
     4501 aactgcatct atgtcttaga caagggctgc atcatcgaac acggtagcca tgaggagctc
     4561 ctagacctcg ggggcaccta tcacaagatg tacagcctac aagcaggcgt aatggaagga
     4621 gcctaagata atctagacca tagcttctat attcgaaaag atttcttaaa aatcaaaatc
     4681 gagtagtgac atttatgtca ctactttttt gttgtcttgc aacctataat aaaaccatag
     4741 cttgagagaa aaagctaaaa aataatattt taggaggttg ttgctatgac aaggcaaaca
     4801 aataacaatt ttgaactcct tgaccttgag tcacttacaa acgttgaagg tggtggatgg
     4861 gttaagtgtt atgccggcac aattggatct gctctagtag gatcagcagg aggcccagta
     4921 ggttactggg gaggagcttt agttggttac gccacattct gctaatattt aggtgaccct
     4981 atgtttaaag ataaaaaaat gtatttacta gccattttcc ttttaggatt tggaattgct
     5041 aaccttttta gaaatttaga ttttgtgcat catattatta atttggtagg gttaacatta
     5101 atcacttata gtttgatttt tagtaaatgg gagcgactca aaaaatagaa gtattcgaaa
     5161 tgtagagttc ctaaaaatca aaatcgagta gtgacatcca tgtcactact tttttgttgt
     5221 cttccagcct ataataaaat catagcttga gagcaaacgc taaaaaatag tttaggaggt
     5281 tgttgctatg acaaggcaaa caaataacaa ttttgaactc cttgaccttg aggcacttgc
     5341 aaacgttgaa ggtggtgatg gattatgttt gatttgaaaa gttatatttt agggatggtt
     5401 tgcatggcct tgatgacttt tttggataag cctattatgt catttcttga aaaacacaag
     5461 gctaccaatt ccgttaataa gaaatcctaa ctgagatgtc ttgtcaattg ctggtctgtg
     5521 aatagcatgt gaattatgat tgaaaatttc gatataagag aagaggtatt tgtaatcatg
     5581 accaaaaaac gcctagtgtc tcgaatgatg tctatgggct tcgtccttgt tgccttacat
     5641 aactttggag aaaaactgaa ttttggactt caatgcctaa atcttatcgg gttatgttta
     5701 tttctctttc ttatgtgtac ggttatcaag gatataaggt cagacaagta gtgacattta
     5761 tgtcactact tttttatcgg cttccaatct ataataaaat tcatagatta tgcacagact
     5821 agctaaaaac actttaagga gaaaattatg tttaaaaact caaaaccgta tttactggct
     5881 accattctca ttggaatggg cctcgcaaat ctatttagaa gcttggatgc agttcaccat
     5941 accattaact tgctagggct aacggtgctt ctttatagct tactttttaa aaagtgggta
     6001 cagtttcaaa agtaaccttt ggtcactttg aacgtaagat gcttgcaaat gcttattttt
     6061 gatgttcccg aagtaaaatt attcttgcta atgatagcgg agattatatt atatttgatt
     6121 gcatatcttt gtaatagaga aaacaaagat atgtatattc gcctatttaa agtatcagta
     6181 ctaatgacac tactgtatta catctccagt agaatgtaat cgctaagggc ttacttgaaa
     6241 tcttacagct gtataataaa atacagagag gaatagagtt aaatgtaata gcttattagg
     6301 tttgcaagac tgactgaggt tattcatagt ttaggtgttt tatcatgaag ttaaagaata
     6361 ttagttcgag tgtattgcga tcttttagaa ccatcactgc tgcgttggca gttttcctta
     6421 taagtatcag cctttctctc tacaaaagca agatctcgcc aggaacttgg ctagcagtcg
     6481 gagcactagc tttagtagtc atttttgtta atggactgct ctaccgtatg cttaagaagc
     6541 gtccagattc agtaaatctg ttaacaatac ggcagtcctt cattgtcttt cttgtcatct
     6601 catttcttgt gctttgtgta gagttttaca cattacttac atttagtgat accacagacc
     6661 gcataatgtt ggtcgtatta atgcttttgt taattctctg tgattttcta gcttacttgc
     6721 aagtcaaaaa atattttaaa aaatagaaaa tatagtaacc atttgtgaca ttattcgatt
     6781 tacgttgcat aaaagtgtta taataagaaa gtgattaagt aaatatgtga aaattagagg
     6841 aagatttcca atgattgaag gatgttcttc tatcgtataa aaatatttgc aaggtctggg
     6901 tcttcaaaaa atgtcctgaa aggaggatta ctatttgaaa caatcgctta gttctagaaa
     6961 atacataaaa tttatcctac aagttatctt ggctgtctgt attcaatgtg tgataacatt
     7021 cttctggcat caagaaagaa catttttatt ttataccttg tcactttatg tttctttatc
     7081 gctctctgat gatcttagtc agctcatttt tagaaatgat aagtgatgtg gttactctaa
     7141 tctggtacga gtaatgcgac agatacgagg ctagaatgct gtttatgata gatatgctta
     7201 taaaaatagt gtttatctac gctttgtagg tgtaattcaa tatattgaaa actttctgtt
     7261 taagagaagt gtgaggttta tgttttatgt caaaaaattt acgtgccctt acggctattg
     7321 ttttatctca attgcttatt gagtgggtag gattcttttt aggtattcct cttagtaaga
     7381 ttctagtttt aacagtactt agtagtctag tagagatttt gatgcatctt atcctaagca
     7441 aaaaatcaaa agttactttg ggtgataaag aaataggaca tcaatacttt ttattcttta
     7501 agaagacact ctggctttcc attttgtttg ttgcaatttt tcttttttat acgataatca
     7561 aatctgatag ctttatgctc tatttttact ggcatatctt tgtattattc cattgtcttg
     7621 gctacatcat ttgtttaaat aatattaaaa taaatcgtaa aaattga
//
