LOCUS       NZ_LS483436.1          23263 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_LS483436.1 Streptococcus intermedius strain NCTC11324 chromosome
            1, complete sequence.
ACCESSION   NZ_LS483436
VERSION     NZ_LS483436.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:19:23
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 133835
            Orig. end    :: 157098
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23263
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[143835:147098]"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13263
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
     cand_cluster    1..23263
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF04055 and TIGR01716)"
                     /kind="single"
                     /product="RaS-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..23263
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RaS-RiPP"
                     /region_number="1"
                     /rules="(PF04055 and TIGR01716)"
                     /tool="antismash"
     CDS             complement(955..1305)
                     /locus_tag="ctg1_112"
                     /transl_table=11
                     /translation="MKMDWFKYTRHVLVWWFSTLFFFTIISADYVDVQVATLVACLFAP
                     FLFEPSSIKPKTKWIIDLAIIVISVFAVLFTQTYRIAFTYSEITYLLISLIILILIDLV
                     ISHKGFTKRIVK"
     CDS             1561..2022
                     /locus_tag="ctg1_113"
                     /transl_table=11
                     /translation="MSSKNTSDSIEEYIKTLLAQAGIAELKRSEIADVFQVVPSQINYV
                     IKTRFTESRGYIVESKRGGGGYIRIGRIEFSNHHELLCDLLHSVGEQISHQVFTDIIQL
                     LFDEQIMTEREGNLLLATTTDRVLGTNAAQIRARMLKKILQQVDRKGKN"
     PFAM_domain     1576..1779
                     /aSDomain="CtsR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05848.13"
                     /description="CtsR N-terminal HTH domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_113_0001"
                     /evalue="1.30E-31"
                     /label="ctg1_113"
                     /locus_tag="ctg1_113"
                     /protein_end="73"
                     /protein_start="5"
                     /score="108.4"
                     /tool="antismash"
                     /translation="TSDSIEEYIKTLLAQAGIAELKRSEIADVFQVVPSQINYVIKTRF
                     TESRGYIVESKRGGGGYIRIGRI"
     PFAM_domain     1792..1995
                     /aSDomain="CtsR_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF17727.3"
                     /description="CtsR C-terminal dimerization domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_113_0002"
                     /evalue="9.90E-16"
                     /label="ctg1_113"
                     /locus_tag="ctg1_113"
                     /protein_end="145"
                     /protein_start="77"
                     /score="57.8"
                     /tool="antismash"
                     /translation="HHELLCDLLHSVGEQISHQVFTDIIQLLFDEQIMTEREGNLLLAT
                     TTDRVLGTNAAQIRARMLKKILQ"
     CDS             2026..4455
                     /gene_functions="other (smcogs) SMCOG1223:ATPase (Score:
                     947.6; E-value: 1e-286)"
                     /gene_kind="other"
                     /locus_tag="ctg1_114"
                     /transl_table=11
                     /translation="MKYSKALTESIESAQLLASHFETDYLESWQLLIAMANNPYSVAGS
                     VLNDYPLEIDDFEKAAFHITGKVYQQEGDFTIWPFSYRMKVLFLTAEQIAGAVHANNLG
                     TEHILLAMLFDQGSLAARILEFIGFSYEDKEGVLRMTDLRKNLEHKASWNKEDLKAIRH
                     LNKSAAATRQTMANMMGMPPATSGGLEDYTRDLTEMAHMGLLEPIIGRDKEISRILQIL
                     SRKTKNNPVLVGDAGVGKTALALGLAQRVADGQVPNELAKMRVLELDLMNVVAGTRFRG
                     DFEERMNNIINDIEADGHVILFIDELHTIMGSGSGIDSTLDAANILKPALAKGTLRTIG
                     ATTQEEYQKYIEKDAALSRRFAKVTIEEATVADSIAILQGLKKSYEDHHKVVITDSAIE
                     TAVKYAHRYLTSKHLPDSAIDLLDEAAARVQNKSPQNHVKAELSAADEALMAGDWNKVD
                     TLLEKESQPIVYKLRVKDEDVLATLSSLSGIPVQKLTQTDAKKYLNLEKELHKRVIGQN
                     EAISAISRAIRRNQSGIRTSKRPIGSFMFLGPTGVGKTELAKALAEVLFDDETALIRFD
                     MSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNRPYSVLLFDEVEKAHPDIFNVLLQ
                     VLDDGVLTDSKGRKVDFSNTIIIMTSNLGATSLRDDKTVGFGARDVRFDHENMEKRMME
                     ELKKAYRPEFINRIDEKVVFHSLTSEDMQEVVKIMVQPLISSLAEKGIKLKFQPSALKL
                     LAQEGYDPEMGARPLRRILQTRVEDHLSELLLAGELKTGQSLKVGVKAGKLKFEVL"
     PFAM_domain     2296..2424
                     /aSDomain="Clp_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02861.22"
                     /description="Clp amino terminal domain, pathogenicity
                     island component"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_114_0003"
                     /evalue="6.80E-05"
                     /label="ctg1_114"
                     /locus_tag="ctg1_114"
                     /protein_end="133"
                     /protein_start="90"
                     /score="23.0"
                     /tool="antismash"
                     /translation="AEQIAGAVHANNLGTEHILLAMLFDQGSLAARILEFIGFSYED"
     PFAM_domain     2716..3072
                     /aSDomain="AAA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00004.31"
                     /description="ATPase family associated with various
                     cellular activities (AAA)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_114_0004"
                     /evalue="9.20E-12"
                     /label="ctg1_114"
                     /locus_tag="ctg1_114"
                     /protein_end="349"
                     /protein_start="230"
                     /score="45.6"
                     /tool="antismash"
                     /translation="VLVGDAGVGKTALALGLAQRVADGQVPNELAKMRVLELDLMNVVA
                     GTRFRGDFEERMNNIINDIEADGHVILFIDELHTIMGSGSGIDSTLDAANILKPALAKG
                     TLRTIGATTQEEYQK"
     PFAM_domain     3136..3363
                     /aSDomain="AAA_lid_9"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF17871.3"
                     /description="AAA lid domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_114_0005"
                     /evalue="1.20E-25"
                     /label="ctg1_114"
                     /locus_tag="ctg1_114"
                     /protein_end="446"
                     /protein_start="370"
                     /score="89.5"
                     /tool="antismash"
                     /translation="VADSIAILQGLKKSYEDHHKVVITDSAIETAVKYAHRYLTSKHLP
                     DSAIDLLDEAAARVQNKSPQNHVKAELSAAD"
     PFAM_domain     3640..4155
                     /aSDomain="AAA_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07724.16"
                     /description="AAA domain (Cdc48 subfamily)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_114_0006"
                     /evalue="6.60E-54"
                     /label="ctg1_114"
                     /locus_tag="ctg1_114"
                     /protein_end="710"
                     /protein_start="538"
                     /score="182.7"
                     /tool="antismash"
                     /translation="RPIGSFMFLGPTGVGKTELAKALAEVLFDDETALIRFDMSEYMEK
                     FAASRLNGAPPGYVGYEEGGELTEKVRNRPYSVLLFDEVEKAHPDIFNVLLQVLDDGVL
                     TDSKGRKVDFSNTIIIMTSNLGATSLRDDKTVGFGARDVRFDHENMEKRMMEELKKAYR
                     PEFINRIDE"
     PFAM_domain     4174..4416
                     /aSDomain="ClpB_D2-small"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10431.11"
                     /description="C-terminal, D2-small domain, of ClpB protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_114_0007"
                     /evalue="6.70E-24"
                     /label="ctg1_114"
                     /locus_tag="ctg1_114"
                     /protein_end="797"
                     /protein_start="716"
                     /score="83.8"
                     /tool="antismash"
                     /translation="LTSEDMQEVVKIMVQPLISSLAEKGIKLKFQPSALKLLAQEGYDP
                     EMGARPLRRILQTRVEDHLSELLLAGELKTGQSLKV"
     CDS             4502..4942
                     /locus_tag="ctg1_115"
                     /transl_table=11
                     /translation="MNIREMVEEDYDQVYQLWLSCASIGLNHLDDSKEGIAQFLKRNPQ
                     TCLVAVENQIIIGAILVGFDGRRAYIYHTAVHPSYRRRGIARKLVETVLIVLDELKIHK
                     VALVVFKRNTEGNHFWETLGFSTREDLIYRNQARTEMTRIDT"
     PFAM_domain     4544..4876
                     /aSDomain="Acetyltransf_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00583.27"
                     /description="Acetyltransferase (GNAT) family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_115_0008"
                     /evalue="6.40E-15"
                     /label="ctg1_115"
                     /locus_tag="ctg1_115"
                     /protein_end="125"
                     /protein_start="14"
                     /score="55.5"
                     /tool="antismash"
                     /translation="YQLWLSCASIGLNHLDDSKEGIAQFLKRNPQTCLVAVENQIIIGA
                     ILVGFDGRRAYIYHTAVHPSYRRRGIARKLVETVLIVLDELKIHKVALVVFKRNTEGNH
                     FWETLGF"
     CDS             complement(5018..5989)
                     /locus_tag="ctg1_116"
                     /transl_table=11
                     /translation="VTNLNTPFLIGDVKIPNRTVLAPMAGVTNSAFRTIAKELGAGLVV
                     MEMVSDKGIQYNNKKTLHMLHIDEEEHPVSIQLFGSDEDSLARAAEFIQENTQTDIVDI
                     NMGCPVNKIVKNEAGAKWLKDPEKIYSIINKVRSLLDIPLTVKMRTGWADASLAVENAL
                     AAEAAGVAALAMHGRTREQMYTGHADLESLHNVAQALTKIPFIANGDIRTVQDAQQRIE
                     EVGADAVMIGRAAMGNPYLFHQINHYFETGEILPDLSFEDKMQVAYDHLKRLIDLKGEH
                     IAVREFRGLAPHYLRGTAGAAKLRGAIAQANSLAEIEALLQV"
     aSDomain        complement(5024..5962)
                     /aSDomain="TIGR00737"
                     /aSTool="tigrfam"
                     /description="nifR3_yhdG: putative TIM-barrel protein,
                     nifR3 family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_116_0001"
                     /evalue="1.90E-108"
                     /identifier="TIGR00737"
                     /label="ctg1_116"
                     /locus_tag="ctg1_116"
                     /protein_end="322"
                     /protein_start="9"
                     /score="360.4"
                     /tool="antismash"
                     /translation="IGDVKIPNRTVLAPMAGVTNSAFRTIAKELGAGLVVMEMVSDKGI
                     QYNNKKTLHMLHIDEEEHPVSIQLFGSDEDSLARAAEFIQENTQTDIVDINMGCPVNKI
                     VKNEAGAKWLKDPEKIYSIINKVRSLLDIPLTVKMRTGWADASLAVENALAAEAAGVAA
                     LAMHGRTREQMYTGHADLESLHNVAQALTKIPFIANGDIRTVQDAQQRIEEVGADAVMI
                     GRAAMGNPYLFHQINHYFETGEILPDLSFEDKMQVAYDHLKRLIDLKGEHIAVREFRGL
                     APHYLRGTAGAAKLRGAIAQANSLAEIEALLQ"
     PFAM_domain     complement(5027..5929)
                     /aSDomain="Dus"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01207.19"
                     /description="Dihydrouridine synthase (Dus)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_116_0009"
                     /evalue="4.50E-89"
                     /label="ctg1_116"
                     /locus_tag="ctg1_116"
                     /protein_end="321"
                     /protein_start="20"
                     /score="298.6"
                     /tool="antismash"
                     /translation="LAPMAGVTNSAFRTIAKELGAGLVVMEMVSDKGIQYNNKKTLHML
                     HIDEEEHPVSIQLFGSDEDSLARAAEFIQENTQTDIVDINMGCPVNKIVKNEAGAKWLK
                     DPEKIYSIINKVRSLLDIPLTVKMRTGWADASLAVENALAAEAAGVAALAMHGRTREQM
                     YTGHADLESLHNVAQALTKIPFIANGDIRTVQDAQQRIEEVGADAVMIGRAAMGNPYLF
                     HQINHYFETGEILPDLSFEDKMQVAYDHLKRLIDLKGEHIAVREFRGLAPHYLRGTAGA
                     AKLRGAIAQANSLAEIEALL"
     CDS             complement(5976..6938)
                     /locus_tag="ctg1_117"
                     /transl_table=11
                     /translation="MVRGRTTKSLSYEILIFVPLPFLFYVTIKGMDKIIKTISENGAFR
                     AYVLDSTETVRTAQEKHQTLASSTVALGRTLIASQILAANEKGDTKITVKVLGTSSLGA
                     IITVADTKGTVKGYVQNSGVDIKKTATGEVLVGSFVGNGEFLVITDYGTGNPYHSMTPL
                     VSGEIGEDLAFYLTESQQTPSAVGLNVLLDTNDKVKVAGGFLLQVLPGAKEEEITHFEK
                     RIQEMPAISTLLESENHIEALLSAIYGNEPYKRLSEEELRFQCDCSKERFLNALSSLPK
                     SDLEEMRDEDHGAEITCQFCQSTYHFDEKDLEELIRDKS"
     PFAM_domain     complement(6015..6845)
                     /aSDomain="HSP33"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01430.21"
                     /description="Hsp33 protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_117_0010"
                     /evalue="1.70E-78"
                     /label="ctg1_117"
                     /locus_tag="ctg1_117"
                     /protein_end="308"
                     /protein_start="31"
                     /score="263.8"
                     /tool="antismash"
                     /translation="DKIIKTISENGAFRAYVLDSTETVRTAQEKHQTLASSTVALGRTL
                     IASQILAANEKGDTKITVKVLGTSSLGAIITVADTKGTVKGYVQNSGVDIKKTATGEVL
                     VGSFVGNGEFLVITDYGTGNPYHSMTPLVSGEIGEDLAFYLTESQQTPSAVGLNVLLDT
                     NDKVKVAGGFLLQVLPGAKEEEITHFEKRIQEMPAISTLLESENHIEALLSAIYGNEPY
                     KRLSEEELRFQCDCSKERFLNALSSLPKSDLEEMRDEDHGAEITCQFCQSTYHFD"
     CDS             complement(7057..8328)
                     /locus_tag="ctg1_118"
                     /transl_table=11
                     /translation="MSQEFNFDIDKIANNAISKTDRTTEIIESTETQANGQMNFLEKLT
                     PEQQDAIIAKAPQLVDNFISDQNTLLDFGQAAVEEVNNTVNRILAEQKKLQIPQVDELL
                     KNTNKELNGFVAKYKDTQIAELDKKPNFLEKLFKQSKNTLQEFYFDSQNIEQKMDSMAA
                     TVVKQEDLLARNIVSAEMLIEDNTKSIENLVGVISFIEATQKEAGARASTLQNEVAQLD
                     TATLDYQTKSQELARLTEVVNTLEQQHTEYISRLYVAWATTPQMRNLVKVSSDMRQKLG
                     MLRRNTIPTMKLSIAQLGILQQSMKSGQVADAISNANNAALQMLAETSKEVIPQMERIS
                     QNPTIAVESVTKLAESLVAQNQGIISAIDKGREKRALLEATVIKSAETINDSVKLRDQK
                     IIQALLDQGKEIQKEVDKPTTSET"
     PFAM_domain     complement(7177..8139)
                     /aSDomain="TelA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05816.13"
                     /description="Toxic anion resistance protein (TelA)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_118_0011"
                     /evalue="1.40E-18"
                     /label="ctg1_118"
                     /locus_tag="ctg1_118"
                     /protein_end="384"
                     /protein_start="63"
                     /score="67.2"
                     /tool="antismash"
                     /translation="ISDQNTLLDFGQAAVEEVNNTVNRILAEQKKLQIPQVDELLKNTN
                     KELNGFVAKYKDTQIAELDKKPNFLEKLFKQSKNTLQEFYFDSQNIEQKMDSMAATVVK
                     QEDLLARNIVSAEMLIEDNTKSIENLVGVISFIEATQKEAGARASTLQNEVAQLDTATL
                     DYQTKSQELARLTEVVNTLEQQHTEYISRLYVAWATTPQMRNLVKVSSDMRQKLGMLRR
                     NTIPTMKLSIAQLGILQQSMKSGQVADAISNANNAALQMLAETSKEVIPQMERISQNPT
                     IAVESVTKLAESLVAQNQGIISAIDKGREKRALLEATVIK"
     CDS             complement(8347..9165)
                     /locus_tag="ctg1_119"
                     /transl_table=11
                     /translation="MPRRNYNNVRSRRWIGILLILIAVGIIIQYLIPILLSIGIGYGIY
                     YYATHKPKKITEPSASQQIEDLKQEIRAADSRIKQLDNYLKEKSYANYQQLADQLLPQL
                     SYIQGRADTLKKYISPEIYQRIQRKVQNVTTDIHEQLHNLHAQTSEGLKLNLEELAPEL
                     LETIHNIQIDHEAILKKISQSESNNKEELTAIHQSQMEHYEDILEGYLKIKTSPKDFYN
                     AEERLSSAKAAIEQFDLDLDETLRQLNEADLRDFDISLRILSKKEPNTEL"
     CDS             9362..9643
                     /locus_tag="ctg1_120"
                     /transl_table=11
                     /translation="MNVEHHLFNRERNNKMKAAVFVEPEKMEVREVARPGAVVGRVGVP
                     HTGDINIGDYWMVNLAMTGGPASCTTYDKEVLLKAVLGGQINPGKVFT"
     CDS             10001..10855
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: TIGR01716"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_121"
                     /sec_met_domain="TIGR01716 (E-value: 1e-44, bitscore:
                     149.5, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHFGKIFKKFRQSRGIKLKDVAKHGLSKSQLSRFERGETDLTIT
                     KFIRALQVINMPIDEFMYAVHDFRRDELNELLERIRVYITTRDILNLKKLLIEQQEKIP
                     EHQIFHELNIILIKIKLQDISGEDSVSEQDIKHLIDYLFSVEFWGNYEILLFANTLDVF
                     NHETFMVLSREMVRRSDFYKEIPNNRRIISTLLLNSYITCIERCELMDAVYFEKQLKAC
                     FFIETEIYERLVFQYAKELYKLKKTNDTRSIIEMKKYIAALKLAGSNGLAETFDIHLTK
                     LLK"
     PFAM_domain     10025..10183
                     /aSDomain="HTH_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01381.24"
                     /description="Helix-turn-helix"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_121_0012"
                     /evalue="1.00E-07"
                     /label="ctg1_121"
                     /locus_tag="ctg1_121"
                     /protein_end="61"
                     /protein_start="8"
                     /score="32.0"
                     /tool="antismash"
                     /translation="KKFRQSRGIKLKDVAKHGLSKSQLSRFERGETDLTITKFIRALQV
                     INMPIDEF"
     aSDomain        10187..10852
                     /aSDomain="TIGR01716"
                     /aSTool="tigrfam"
                     /description="RGG_Cterm: transcriptional activator,
                     Rgg/GadR/MutR family, C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_121_0002"
                     /evalue="2.50E-44"
                     /identifier="TIGR01716"
                     /label="ctg1_121"
                     /locus_tag="ctg1_121"
                     /protein_end="284"
                     /protein_start="62"
                     /score="149.5"
                     /tool="antismash"
                     /translation="YAVHDFRRDELNELLERIRVYITTRDILNLKKLLIEQQEKIPEHQ
                     IFHELNIILIKIKLQDISGEDSVSEQDIKHLIDYLFSVEFWGNYEILLFANTLDVFNHE
                     TFMVLSREMVRRSDFYKEIPNNRRIISTLLLNSYITCIERCELMDAVYFEKQLKACFFI
                     ETEIYERLVFQYAKELYKLKKTNDTRSIIEMKKYIAALKLAGSNGLAETFDIHLTKLLK
                     "
     CDS             10940..11047
                     /locus_tag="ctg1_122"
                     /transl_table=11
                     /translation="MKLDMKPNQKLDLSVKKVDLSVAVLTRDSSKAHGH"
     CDS             11118..11381
                     /locus_tag="ctg1_123"
                     /transl_table=11
                     /translation="MDERLWLTNWNSLYIQNDIFFTDAIKPVYVGFKISENCNQRCSHC
                     WAGKNLTINHSFDEIIAALNKIKILNPLHITITGGEPLVHEH"
     CDS             11382..12194
                     /locus_tag="ctg1_124"
                     /transl_table=11
                     /translation="LDILGYAKKNFPIVELFTNAVLFSEKSIKKLSSLFGDLDFIQVSL
                     DGLRTTYKKQRGSDDFQKVIENIKLIVKYNLNIRVNMTITHLNIEEMIDVYELVDSIGI
                     TSFSISPVYPLRRGKKLVSLVDYTQYLHKGKLIEKMHAKRKSQMNLTVIYPMEVLSEKA
                     TYTQESTYFQRFNTDLLHWTIDGRGDIFHFMDQFIYKELKVGNIYENTIEELEANDYTI
                     QKNVLEHSNQGLKCMNCSLVESCPGFAYAKSYPEIAFSYKRCVFNEKQ"
     CDS             12181..13263
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_125"
                     /sec_met_domain="PF04055 (E-value: 3.9e-12, bitscore: 43.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 1.4e-15, bitscore:
                     54.2, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 2.5e-09, bitscore: 34.3,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNNNLLKISQDLGNDFDLPYYIYTKVKTDTNEKVSAPLKIGLKL
                     TNACHFRCPYCFVYKDNDYVDFDNLKLIFQKLPQLPFEVYLTGGEAILHPQFSEIVDYL
                     TNLGILVKLHTTGVINMQSRNYILNNLSKFSSIQISIDSIKNFDKLRPNIIDKNPLERI
                     ISFVKQCKEKKYKNLLVNTVISSLNVNELDEIMEFCLCHNLFKVQLSTIFTTSKRLLVS
                     DEIYAKHYNQIITKYSKKGLCFQNSPFCHPWSYAIKHNLKYDSPMYCPAQKTEFEIDMQ
                     GNVYPCPFLHDETHKMGNLLSDTFDEVWNSGVKELNKASWSENKKCKSCALFKDCGGGC
                     YALAYVSQLNYDKRCILHEN"
     PFAM_domain     12313..12774
                     /aSDomain="Radical_SAM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04055.23"
                     /description="Radical SAM superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_125_0013"
                     /evalue="2.20E-11"
                     /label="ctg1_125"
                     /locus_tag="ctg1_125"
                     /protein_end="198"
                     /protein_start="44"
                     /score="44.5"
                     /tool="antismash"
                     /translation="LTNACHFRCPYCFVYKDNDYVDFDNLKLIFQKLPQLPFEVYLTGG
                     EAILHPQFSEIVDYLTNLGILVKLHTTGVINMQSRNYILNNLSKFSSIQISIDSIKNFD
                     KLRPNIIDKNPLERIISFVKQCKEKKYKNLLVNTVISSLNVNELDEIMEF"
     PFAM_domain     12985..13170
                     /aSDomain="SPASM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13186.8"
                     /description="Iron-sulfur cluster-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_125_0014"
                     /evalue="2.80E-08"
                     /label="ctg1_125"
                     /locus_tag="ctg1_125"
                     /protein_end="330"
                     /protein_start="268"
                     /score="34.2"
                     /tool="antismash"
                     /translation="CPAQKTEFEIDMQGNVYPCPFLHDETHKMGNLLSDTFDEVWNSGV
                     KELNKASWSENKKCKSC"
     aSDomain        12985..13230
                     /aSDomain="TIGR04085"
                     /aSTool="tigrfam"
                     /description="rSAM_more_4Fe4S: radical SAM additional
                     4Fe4S-binding SPASM domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_125_0003"
                     /evalue="3.40E-15"
                     /identifier="TIGR04085"
                     /label="ctg1_125"
                     /locus_tag="ctg1_125"
                     /protein_end="350"
                     /protein_start="268"
                     /score="54.2"
                     /tool="antismash"
                     /translation="CPAQKTEFEIDMQGNVYPCPFLHDETHKMGNLLSDTFDEVWNSGV
                     KELNKASWSENKKCKSCALFKDCGGGCYALAYVSQLN"
     CDS             13253..13513
                     /locus_tag="ctg1_126"
                     /transl_table=11
                     /translation="MKISKNWFVRFEPNFQSSQKTILYNKLNGDLYELSEVYFDFINNI
                     NQKKEFSILIMKKYNINQSDVEQISKTILENLISLGVILND"
     CDS             13506..14402
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 150.9; E-value:
                     7.8e-46)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_127"
                     /transl_table=11
                     /translation="MTDISISNLKKVFHGKVVLDIPQFTASKSEIISVLGVNGAGKSTF
                     IKTISGLLLQDEGQVNICGYSNFSPKIHQVTKFVLESGKGYYDYLTANQNIDYFLKLNK
                     ASRSDLALNIAVLFQKLDFQQHADTLVSELSQGTRQKLSLIIALLCRPEVLCLDEPTNG
                     LDVIAKKQLAQILLGLSKGKNTIVLLTTHDISFARDISSRVLVMDNGRIKKDDSFEHVF
                     SRKNTWKKYEIVLPLSFQNIIERSFQNLHYVIQDEEMIIQTQEKDVKDRLLKETDIVRF
                     EEIEQDIEEILYEVLSK"
     PFAM_domain     13572..13991
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_127_0015"
                     /evalue="3.40E-21"
                     /label="ctg1_127"
                     /locus_tag="ctg1_127"
                     /protein_end="162"
                     /protein_start="22"
                     /score="76.3"
                     /tool="antismash"
                     /translation="QFTASKSEIISVLGVNGAGKSTFIKTISGLLLQDEGQVNICGYSN
                     FSPKIHQVTKFVLESGKGYYDYLTANQNIDYFLKLNKASRSDLALNIAVLFQKLDFQQH
                     ADTLVSELSQGTRQKLSLIIALLCRPEVLCLDEPTN"
     CDS             14399..15136
                     /locus_tag="ctg1_128"
                     /transl_table=11
                     /translation="MMKDVKREFLRQIQETMQFKFNLFFANFSIFIMVSSYLHYFEESQ
                     NKFTLFCLLFTWYFTSHSITHPTFFIEDDIYDRTLISVIQSKKSVVHVLLFKILVQILI
                     DLIKAIPIFLILSFLSDITFPASIVEIFVIVLICLLVILILYGLGFCLSSFCLTLNRTS
                     SFTSLLSYFILFFTGILKPFDGFLGILGHIFPFYTLREFIHRPSITEVLIILWYGVVYW
                     SIGFVLFHIFLKMAKKKGNIFHV"
     PFAM_domain     14411..14956
                     /aSDomain="ABC2_membrane"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01061.26"
                     /description="ABC-2 type transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_128_0016"
                     /evalue="1.20E-10"
                     /label="ctg1_128"
                     /locus_tag="ctg1_128"
                     /protein_end="186"
                     /protein_start="4"
                     /score="41.3"
                     /tool="antismash"
                     /translation="VKREFLRQIQETMQFKFNLFFANFSIFIMVSSYLHYFEESQNKFT
                     LFCLLFTWYFTSHSITHPTFFIEDDIYDRTLISVIQSKKSVVHVLLFKILVQILIDLIK
                     AIPIFLILSFLSDITFPASIVEIFVIVLICLLVILILYGLGFCLSSFCLTLNRTSSFTS
                     LLSYFILFFTGILKPFDGF"
     CDS             15129..15719
                     /locus_tag="ctg1_129"
                     /transl_table=11
                     /translation="MFNELKRYFYYRKQYKFDSLCDAIYTLIFIVGIIMIFSGQTLLNI
                     LYFYIYFLVTNITLLANEELEYEIRTSQYDNLITSKYKVKRIYLRRIVAYLVWSSILFI
                     ISLFVSNVFGSSTHFVFPKMSIFGAIVFVSINLVLFLVFYMGVIKLTEKFKRVSVLLNF
                     LNTIFLFYSGLVFPTSFETFADMLNKILSLGNN"
     CDS             15951..16508
                     /locus_tag="ctg1_130"
                     /transl_table=11
                     /translation="MSLTSQIITAEFPDLEKVEQLNTEAFPEEERAPLSELLRYGDGEY
                     SHFFAFYDGDEFVGFAFSVYNERAFYVSFFAIMPHLRSHGYGGKLIDKLVDFYQRTMIL
                     EVERLDEPCDNLEQRKARMDFYKRNGFRSSHAYLEYDGLSFEILYKGPFFDEGAYRDIF
                     KKIQEDGYFEFEIKHGHGRDWE"
     PFAM_domain     16008..16343
                     /aSDomain="Acetyltransf_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00583.27"
                     /description="Acetyltransferase (GNAT) family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_130_0017"
                     /evalue="1.60E-07"
                     /label="ctg1_130"
                     /locus_tag="ctg1_130"
                     /protein_end="131"
                     /protein_start="19"
                     /score="31.7"
                     /tool="antismash"
                     /translation="QLNTEAFPEEERAPLSELLRYGDGEYSHFFAFYDGDEFVGFAFSV
                     YNERAFYVSFFAIMPHLRSHGYGGKLIDKLVDFYQRTMILEVERLDEPCDNLEQRKARM
                     DFYKRNGF"
     CDS             complement(16778..17362)
                     /locus_tag="ctg1_131"
                     /transl_table=11
                     /translation="VNINHLLEKIAVDVPILQATFGKDKSIVIKPKSTNFGLGISIFQE
                     PTNLDSSQKALEIAFSEDSSVLGEEFIAGTEYCFFVLDGKCEAVLLRLPANVRGDGRHT
                     IRELVATKNANPLRSRDHRSPLERIKLGEIELLMLAQQGYKADDILPKGVQVFLRCNSN
                     ISTGGDSVDVTEIMHTSYKELAAEMATAMGA"
     CDS             17652..18944
                     /locus_tag="ctg1_132"
                     /transl_table=11
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIVI
                     GGKKYKLHLIPSGIFFPEKISVIGNGMVVNPKSLVHELAYLHEEGVTTDNLRISDRAHV
                     ILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERLERN
                     LAEKNRLFEKLYDSTAIRFDDMFEEYYAYGQQIKQYVTDTSVILNDALDQGKRVLFEGA
                     QGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGPFPTEL
                     FDEVGNRIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVLTGLDTV
                     KICVAYDLDGERIDYYPASLEQLKRCKPIYEELPGWSEDITGVRSLEELPENARNYVRR
                     VSELVGVRISTFSVGPDREQTNILESVWSSL"
     PFAM_domain     17664..18911
                     /aSDomain="Adenylsucc_synt"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00709.23"
                     /description="Adenylosuccinate synthetase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_132_0018"
                     /evalue="2.10E-187"
                     /label="ctg1_132"
                     /locus_tag="ctg1_132"
                     /protein_end="420"
                     /protein_start="4"
                     /score="623.0"
                     /tool="antismash"
                     /translation="VVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIVIGGKK
                     YKLHLIPSGIFFPEKISVIGNGMVVNPKSLVHELAYLHEEGVTTDNLRISDRAHVILPY
                     HIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERLERNLAEK
                     NRLFEKLYDSTAIRFDDMFEEYYAYGQQIKQYVTDTSVILNDALDQGKRVLFEGAQGVM
                     LDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGPFPTELFDEV
                     GNRIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVLTGLDTVKICV
                     AYDLDGERIDYYPASLEQLKRCKPIYEELPGWSEDITGVRSLEELPENARNYVRRVSEL
                     VGVRISTFSVGPDREQT"
     aSDomain        17664..18926
                     /aSDomain="TIGR00184"
                     /aSTool="tigrfam"
                     /description="purA: adenylosuccinate synthase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_132_0004"
                     /evalue="5.60E-190"
                     /identifier="TIGR00184"
                     /label="ctg1_132"
                     /locus_tag="ctg1_132"
                     /protein_end="425"
                     /protein_start="4"
                     /score="629.6"
                     /tool="antismash"
                     /translation="VVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIVIGGKK
                     YKLHLIPSGIFFPEKISVIGNGMVVNPKSLVHELAYLHEEGVTTDNLRISDRAHVILPY
                     HIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERLERNLAEK
                     NRLFEKLYDSTAIRFDDMFEEYYAYGQQIKQYVTDTSVILNDALDQGKRVLFEGAQGVM
                     LDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGPFPTELFDEV
                     GNRIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVLTGLDTVKICV
                     AYDLDGERIDYYPASLEQLKRCKPIYEELPGWSEDITGVRSLEELPENARNYVRRVSEL
                     VGVRISTFSVGPDREQTNILES"
     CDS             19199..19480
                     /locus_tag="ctg1_133"
                     /transl_table=11
                     /translation="MNFTDLSNKEQEKIMISKIIRNLKKLGGYATKRELLDAIKKGENT
                     IDENFFEEEKVSQKSGKFINLVITLLIFLSKVCLPRVIFLNQSNRLLN"
     CDS             19499..20098
                     /locus_tag="ctg1_134"
                     /transl_table=11
                     /translation="VKLDEHFASDIQQKAIQFWKNEKKSKQFFKLSFEKELKHSLDDSK
                     ENWRVELTKALKSMSPQKFETFARGLVKEMGIKLDEKIGVSYTNDGGLDGFGDITSTDD
                     FRTNRVAIQAKHWENKVPSSEIDKFRGAMDKYNAEYGIFITTSDFSRSATEAARQGTRV
                     ITLINSEDIADLVAKYKLHVREVMTYELGDFYHTED"
     PFAM_domain     19664..20023
                     /aSDomain="Mrr_cat"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04471.14"
                     /description="Restriction endonuclease"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_134_0019"
                     /evalue="5.90E-28"
                     /label="ctg1_134"
                     /locus_tag="ctg1_134"
                     /protein_end="175"
                     /protein_start="55"
                     /score="97.4"
                     /tool="antismash"
                     /translation="LKSMSPQKFETFARGLVKEMGIKLDEKIGVSYTNDGGLDGFGDIT
                     STDDFRTNRVAIQAKHWENKVPSSEIDKFRGAMDKYNAEYGIFITTSDFSRSATEAARQ
                     GTRVITLINSEDIADL"
     CDS             20110..20577
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1240:riboflavin biosynthesis protein RibD (Score:
                     74.3; E-value: 1.7e-22)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_135"
                     /transl_table=11
                     /translation="MNYTVEEKEFFMREALKEAEIALANDEIPIGCVIVKDGKVIGRGH
                     NAREELQRAVMHAEVMAIEKANQHEHSWRLLDTTLFVTIEPCVMCSGAIGLARIPQVIY
                     GAKNPKFGAAGSLYDILTDERLNHRVELETGILEVECAQMMQDFFRKRRQR"
     PFAM_domain     20128..20568
                     /aSDomain="MafB19-deam"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14437.8"
                     /description="MafB19-like deaminase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_135_0020"
                     /evalue="7.40E-36"
                     /label="ctg1_135"
                     /locus_tag="ctg1_135"
                     /protein_end="153"
                     /protein_start="6"
                     /score="123.0"
                     /tool="antismash"
                     /translation="EKEFFMREALKEAEIALANDEIPIGCVIVKDGKVIGRGHNAREEL
                     QRAVMHAEVMAIEKANQHEHSWRLLDTTLFVTIEPCVMCSGAIGLARIPQVIYGAKNPK
                     FGAAGSLYDILTDERLNHRVELETGILEVECAQMMQDFFRKRR"
     CDS             20574..21116
                     /locus_tag="ctg1_136"
                     /transl_table=11
                     /translation="MKRWLSILFFLLTLLFIGLLIGNVEFQAWAFTRHQNQLSWYIRPI
                     LILPIIYFSYRKSLLGISASIFALFTSMIWFWEPKTTFPLVKEFLTYEQDFLQADWNLK
                     KILFIFLVISFFLLLVRATWLHSWKLLAILLILTAFLKILWSYLDSGRAGLTIVVPAIL
                     GLFICLFFLSFWMKGKS"
     CDS             21343..22209
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR01716"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_137"
                     /sec_met_domain="TIGR01716 (E-value: 5.6e-40, bitscore:
                     134.0, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYYMGEIFRELRTGRHLSLKEATGEEFSYSMLSKFENGTSDISAS
                     KLLIGLENIRTELEEFVYLVRGFQPTSYTLLKNKLWEAQEQKDIKTLWEMYNNEIDQYQ
                     SKKEEEHILNAIVIKGHMFFLDETIKATEVELNFLYDYFFSVEIWGEYELRLFSDIAAL
                     FPIDLYFRYTREMLQRVDFLGDLQKNKNYIYTILLNGLFKAIDKKSLNKAAYFDKKIKE
                     KFFDENEAYLRIVYLFADGQHDYILGQRNEGLTKMKNAISTLEIIGCEHSANYYSKNMS
                     EWLKEFE"
     aSDomain        21529..22197
                     /aSDomain="TIGR01716"
                     /aSTool="tigrfam"
                     /description="RGG_Cterm: transcriptional activator,
                     Rgg/GadR/MutR family, C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_137_0005"
                     /evalue="1.40E-39"
                     /identifier="TIGR01716"
                     /label="ctg1_137"
                     /locus_tag="ctg1_137"
                     /protein_end="285"
                     /protein_start="62"
                     /score="134.0"
                     /tool="antismash"
                     /translation="YLVRGFQPTSYTLLKNKLWEAQEQKDIKTLWEMYNNEIDQYQSKK
                     EEEHILNAIVIKGHMFFLDETIKATEVELNFLYDYFFSVEIWGEYELRLFSDIAALFPI
                     DLYFRYTREMLQRVDFLGDLQKNKNYIYTILLNGLFKAIDKKSLNKAAYFDKKIKEKFF
                     DENEAYLRIVYLFADGQHDYILGQRNEGLTKMKNAISTLEIIGCEHSANYYSKNMSEWL
                     K"
ORIGIN
        1 gttgctgctg aaggactgac tggtgtctat gtgagtggca atatcgctgc tatcgttgaa
       61 gtgaattcag aaacagattt tgtagcaaaa aatgctcaat ttgttgaatt agtaaacgaa
      121 acggctaaag tgattgcaga aggcaaacca gcgaacaatg aagaagcact tgctttgata
      181 atgccttcag gagaaacgct tgaagctgct tatgttagtg caactgctac aattggagaa
      241 aaaatttcat tccgtcgttt tgcagttgtt gaaaaagcag atgatcaagt atttggcgca
      301 taccaacaca atggtggacg tatcggagtt attactgttc tttcaggtag tgacgaagac
      361 cttgcaaaac atgtagcaat gcacgttgcc gcaatgaaac cttctgttct ttcatacaaa
      421 gaattgagtg aagaatttat ccatgatgaa ttggcgcaaa tgaaccataa aattgaccaa
      481 gacaatgaaa gccgtgcaat ggttggtaaa ccagcacttc cacactacaa atttggttct
      541 aaacttcaat tgacagatga agtgattgca caagctgaag aagatattaa agcaggtctt
      601 gcggctgaag gtaagccaga aaaaatctgg gacaaaatca tccctggtaa gatggatcgc
      661 tttatgttag ataacacaaa agtcgaccaa caatatacac ttttagctca agtttatatt
      721 atggatgaca gcaaaactgt tgaagcattc cttgaaagtc aaggtgttac aatcgctggc
      781 ttcacacgtt ttgaagtggg tgatggtatt gaaaaagctg ccaatgattt tgaatcagaa
      841 gtagctgcta caatggctgc tgcacttgga caaaactaag ttaatcaatt atgtaataac
      901 aaacaaaagg ttagagaaca gatgaagttc tctaaccttt tttagctgcg gttactattt
      961 tacaattctt ttagtgaatc ccttgtgaga aataactaaa tcgataagga ttaaaataat
     1021 caaggagatg agtagataag taatttcgga gtaggtaaaa gcgattcggt aagtttgtgt
     1081 aaaaagaaca gcaaagacac tgatgacaat gatggctaaa tcaattatcc attttgtttt
     1141 tggttttatt gaagacggtt caaataaaaa cggggcaaac aaacaggcga ctaatgtagc
     1201 gacttgaaca tctacatagt cagcagaaat aattgtaaaa aagaacaaag ttgaaaacca
     1261 ccaaaccagt acatgacgtg tatatttgaa ccaatccatt ttcattcatt tggcctcctt
     1321 tattgatatc gtcaaatttt catctatatt ataacgcttt aaaattaaaa ggcaagcgtt
     1381 tacacttaaa ttgttactag tagataagct ttttcacttg cttgaataat cagacttttc
     1441 agtttttcat ttagcgcttt ctctttcaaa aatggaagaa tttcggtata atagtcaaag
     1501 atagtcaatg tcagttgtgg atatgattta tagaatgagg tctaaaggga aggagttggc
     1561 atgagtagta aaaatacatc agatagtatt gaagaatata ttaaaactct tttggcgcaa
     1621 gcaggaattg cagagttgaa gcgaagtgag attgcagatg tttttcaagt tgttcctagt
     1681 cagataaact atgtaataaa gacacgattt acagaaagtc gtggctatat tgttgaaagt
     1741 aagcgtggtg gaggtggcta cattcggatt ggtcgaattg aattttccaa tcaccatgag
     1801 ttgctttgtg atttgttgca tagcgttggt gagcagatta gccatcaggt ctttacagat
     1861 attattcagc tgttatttga tgaacagatc atgacagaac gagaagggaa tcttctttta
     1921 gcaacgacaa cagacagggt attggggaca aatgctgcac agattcgtgc gcggatgtta
     1981 aagaaaattt tacagcaagt tgatagaaaa gggaaaaact aatatatgaa atattcaaaa
     2041 gctttgacag aaagtattga atcagcacag ttattagcaa gtcattttga aacggattat
     2101 ttagagtctt ggcagctgtt gattgctatg gcaaataatc cttatagtgt tgctggttca
     2161 gttttaaatg attacccact tgaaattgat gattttgaaa aggcagcttt tcatatcacg
     2221 gggaaagtct atcaacaaga gggagacttt actatttggc cgttttctta tcgcatgaaa
     2281 gtgctatttt tgactgctga acaaattgca ggggcggttc atgctaataa tcttgggaca
     2341 gagcatatat tgctagctat gttatttgac caaggaagct tggcagcgcg tattcttgaa
     2401 tttattggtt ttagttacga agataaagaa ggcgttttgc gcatgacaga tctgcggaaa
     2461 aatttagagc ataaggccag ctggaataaa gaggatttaa aggctattcg tcacctaaat
     2521 aaaagtgctg cagcaacaag acaaacgatg gctaatatga tgggaatgcc tcctgcaacc
     2581 agtggcggac tagaagatta tactcgtgat ctaactgaaa tggctcatat gggcctttta
     2641 gaaccgatca ttgggcggga taaagagatt tctcgcatac ttcagatttt aagtcgtaag
     2701 acaaaaaaca atccggtttt ggtaggagat gcaggagttg ggaagacagc attagctctg
     2761 ggtttggcgc aacgtgtggc agatggtcaa gttccaaatg agcttgcaaa gatgagagtt
     2821 ttagagctag atttaatgaa tgtggtggct ggaactcgtt ttcgtggtga ttttgaagaa
     2881 cggatgaaca atattatcaa tgatattgaa gcagatgggc atgttattct cttcattgat
     2941 gagcttcata ccattatggg ttctggcagc gggattgact cgacattaga tgcagcaaat
     3001 attctcaagc cggctttggc taaaggaacg ctcagaacga tcggtgcaac aacacaagaa
     3061 gagtaccaaa aatatatcga aaaagatgca gctctttcac gaagatttgc caaggttact
     3121 attgaagaag caacggtagc tgacagcatt gctattttac agggactcaa gaaaagttat
     3181 gaagatcacc acaaggtcgt gattacggat tcggcaattg agacggctgt taagtatgcg
     3241 catcgttacc tgactagtaa acatctacct gactcagcga ttgacttgct agacgaagct
     3301 gctgcaaggg tacaaaataa aagcccgcaa aatcacgtaa aagcagaatt gagtgcagca
     3361 gatgaggctt taatggcagg cgattggaac aaagttgata cgttgttgga gaaagagagt
     3421 cagccaattg tttataaatt aagggtgaaa gacgaggatg ttttagcaac actcagcagt
     3481 ttatcaggta ttcctgtgca aaagttgaca caaacagatg cgaagaaata cctcaattta
     3541 gaaaaggagt tacacaaacg agttatcggg cagaatgaag caatttctgc tattagtcga
     3601 gcgattcggc gcaatcaatc tggtatccgc actagcaagc gcccaattgg ctcctttatg
     3661 ttcttagggc caaccggggt cggaaaaact gagctagcta aggctttggc agaagttctc
     3721 tttgatgacg aaacagcgtt aattcgtttt gatatgtccg aatacatgga gaaatttgct
     3781 gctagtcgtc tcaatggagc acctccaggc tatgttggtt atgaagaagg gggagaatta
     3841 actgaaaagg tgcgtaatcg tccttactct gtgctcctct ttgacgaagt ggaaaaagct
     3901 catcctgata ttttcaatgt gctgctccaa gtcctagatg acggggttct gacggatagc
     3961 aagggccgta aggtagattt ttccaatact attatcatta tgaccagcaa tcttggtgcg
     4021 acaagtttac gggacgataa gacggttggg ttcggagcaa gagatgttcg ctttgatcat
     4081 gaaaatatgg aaaaacgaat gatggaagag ctaaagaaag cttatcgtcc agaatttatt
     4141 aaccgaattg atgaaaaggt tgtttttcac agtttgacta gcgaagacat gcaggaagtg
     4201 gtgaaaatta tggtgcaacc gctcatttct agtcttgcag aaaaaggaat taaactcaaa
     4261 ttccaaccga gtgctttgaa gcttctagct caagagggct atgatcctga aatgggagct
     4321 cgtccattgc gtcgaattct acaaactcga gtggaagacc atttatcaga attactttta
     4381 gcaggtgagc taaaaacggg gcaaagcttg aaagtcggtg tcaaggctgg aaaattgaag
     4441 tttgaagtgc tctgagtttc tattcgaagc attcatcagg gagtagataa ggtattttaa
     4501 tatgaacatt cgtgaaatgg tagaagaaga ttacgaccaa gtttaccaat tatggctgtc
     4561 atgtgcaagt ataggcttaa atcatttgga tgattctaag gaggggattg cacagtttct
     4621 aaaaaggaac cctcaaactt gtctggtagc agtagaaaat caaataatta ttggagcgat
     4681 tttagttggc tttgatggtc gaagggcata tatctatcat acagctgttc atccgagtta
     4741 ccgtaggaga gggattgctc ggaagttggt tgagacagtt ttaattgtct tagatgagtt
     4801 aaaaattcac aaggtcgctt tggttgtatt caaaaggaac acagaaggaa atcatttttg
     4861 ggaaacatta ggtttctcta cccgagaaga tttaatttat cgcaatcagg caaggactga
     4921 aatgactcgg atagatacct agtagaaatt actctttaaa taaaaaacac caaccattta
     4981 ggaataattt cccagatgat tggtgttttt ctgatattta gacttggagc aatgcttcaa
     5041 tttctgcgag gctattagct tgtgcgatag cgccacgaag cttggcagct cctgctgttc
     5101 cacgaaggta atgaggtgcc aacccccgaa attctcgaac agcgatatgc tcgcccttga
     5161 ggtcaattag acgtttcaag tgatcgtaag cgacttgcat tttatcctca aagctgagat
     5221 caggcaggat ttctcctgtt tcaaaatagt ggttaatctg atgaaagaga tacggattgc
     5281 ccatagcagc acgcccgatc ataactgcat ctgcccccac ttcttctata cgctgttgag
     5341 catcttgtac ggtacgaatg tcaccattgg caataaaagg gatcttggtt aaggcttgcg
     5401 caacattgtg gaggctttca agatcagcat gcccagtata catctgctcg cgtgtacgac
     5461 cgtgcatagc aagagccgcc acaccagcag cttcagctgc aagagcattt tccacagcta
     5521 gtgaggcatc tgcccaacca gtacgcattt tcacggttaa cggaatatct agaagagaac
     5581 gaactttatt gataatagaa tagatttttt ctggatcttt gagccatttt gctccagctt
     5641 cgtttttgac aattttattg acgggacagc ccatattaat atccacaata tctgtttggg
     5701 tattttcttg gataaattcg gcagcgcgcg ccaaactatc ttcgtcactc ccaaacaact
     5761 gaatggaaac gggatgttct tcttcgtcaa tatgcaacat atggagtgtc tttttgttat
     5821 tgtattgaat gcctttgtct gagaccattt ccatgacgac aagtcctgcg ccaagctctt
     5881 ttgcaattgt ccgaaaagct gaattggtga cgcctgccat gggagcaaga acagtccggt
     5941 tgggaatttt tacatcacca atcaaaaaag gggtattaag atttgtcacg aatgagttcc
     6001 tccaagtctt tttcgtcaaa atgatatgtg ctttgacaga attggcaagt gatttcagcg
     6061 ccgtggtctt catctcgcat ttcttcaaga tctgacttag gtaggcttga gagggcattt
     6121 aaaaaccgtt ctttgctgca atcacattgg aagcggagct cttcttctga caagcgtttg
     6181 tagggttcgt tgccatagat agctgaaagc aaggcttcaa tatggttttc agattccaaa
     6241 agtgttgaaa tagcaggcat ttcttggatt cgtttttcaa agtgggtgat ttcttcttct
     6301 ttggcaccag ggagaacttg caagagaaat ccgccagcaa ccttgacctt gtcgttggta
     6361 tctagtagta cattcaagcc aacagctgaa ggagtttgtt gactttctgt tagatagaat
     6421 gcaaggtctt ctccaatctc accggacaca agtggagtca tagaatgata aggatttcca
     6481 gttccataat ccgtaataac gagaaattcg ccattcccaa cgaatgatcc aaccaacact
     6541 tcacctgttg cagttttttt aatgtccaca ccggaatttt gcacatagcc tttgacagta
     6601 ccttttgtat ctgcgacggt gataatcgca ccaagagagc ttgtccctag tactttgacg
     6661 gtgatttttg tatctccttt ttcgtttgcg gcaaggattt gactggcaat gagtgtgcga
     6721 cctaacgcta cggttgagct agcaagggtc tggtgttttt cctgagctgt tcgaacagtt
     6781 tcggtactat ctagtacata agctcggaaa gccccgtttt ctgaaatagt tttaataatc
     6841 ttatccatac cttttattgt aacataaaaa agaaaaggga gcgggacaaa aatcagtatt
     6901 tcgtaagaaa gtgattttgt tgtcctgccc cgcaccattg acgaggttgg tcattattta
     6961 catagcaaag agttagtgct gtatactgtt actttgtttg gatgaaacag cataccacaa
     7021 gagtttattt ttgtcttacg tccatgtttc agctcgttat gtttcacttg tagtcggttt
     7081 atccacttct ttttggattt cttttccctg atctagcaaa gcttggataa ttttttggtc
     7141 gcgtaattta acagagtcat taatggtttc agcggatttg attacagttg cttcaaggag
     7201 agcgcgtttt tcccgccctt tatcaatggc agagatgatt ccttggtttt gagcgactaa
     7261 gctttcagct aatttggtga cggattcgac agcgattgtt ggattttggg aaatcctctc
     7321 catttgtgga atgacttctt tgctggtttc agctagcatt tgcagcgctg cattgttggc
     7381 attagaaata gcgtctgcta cttgaccaga tttcattgat tgctgcagga ttcctagttg
     7441 agcgatagag agcttcatag tcggaatggt attgcgacgg agcatgccaa gtttttggcg
     7501 catatcagaa gatactttta cgagattacg catttgcggg gtagtggccc aagcgacata
     7561 tagacggctg atgtattctg tatgttgttg ttccaatgta ttcacaacct cagttaagcg
     7621 agccaattct tgtgatttgg tttggtaatc gagagtggca gtatctaatt gtgccacctc
     7681 attttgaaga gtcgaggcac gcgcaccagc ttctttttga gtggcttcga tgaaggaaat
     7741 gacaccgact agattttcaa tggatttggt gttgtcttca attaacattt cggcagaaac
     7801 gatattgcgt gcgagcagat cttcttgctt gacgacagtg gcggccatac tatccatttt
     7861 ttgctcaata ttttgtgaat caaaatagaa ctcttgcaag gtgttcttac tttgtttaaa
     7921 gagtttttct aaaaaatttg gctttttatc tagttctgca atttgagtat ccttatattt
     7981 agcaacaaaa ccatttaact ctttgttggt gttttttaac aattcatcta cttgtgggat
     8041 ttgaagtttc ttttgttcgg ctaaaatgcg attaacagta ttattaactt cttcgactgc
     8101 agcttgccca aaatctaaaa gagtattttg atcggaaata aagttatcta ccagctgagg
     8161 ggcttttgct atgatcgcat cttgttgttc aggagttaat ttctccaaaa agttcatctg
     8221 tccgtttgct tgtgtttcgg ttgattcaat gatttcagta gttctgtctg ttttggaaat
     8281 ggcattatta gcgattttgt cgatgtcaaa gttaaattct tggctcataa ggtctccttt
     8341 tgatggttat agttcggtat tgggttcttt tttacttaaa atcctcaagc tgatatcaaa
     8401 atctcgtaga tccgcttcgt tgagttgacg gagtgtttca tccaagtcta aatcaaactg
     8461 ctcaatagct gctttggcgc tagaaagtcg ttcttctgca ttataaaaat cttttggtga
     8521 ggtcttgatt tttaggtagc cttccaaaat atcctcataa tgctccattt gagactgatg
     8581 gattgcagtt aattcttcct tgttattgct ttctgactga gaaattttct tgagaatcgc
     8641 ttcgtggtcg atttgaatat tgtgaatagt ttcaagtaat tcaggtgcta attcctccaa
     8701 gtttagtttt aaaccttcgg aagtttgagc gtgaagattg tgtagttgct catggatatc
     8761 tgttgttaca ttttgcactt ttcgttgaat tcgctggtaa atttcaggcg agatatattt
     8821 ttttaaggtg tcagctcggc cttgaatata actcaattga ggcaagagct gatcagctaa
     8881 ttgttggtaa tttgcataag atttttcttt cagataattg tccagctgtt tgattcgact
     8941 atctgcagct ctgatttcct gtttcaaatc ttcaatttgc tgactggcgc tgggctctgt
     9001 gatttttttc ggtttatgag ttgcatagta gtaaattccg tagcctatgc cgatggaaag
     9061 aaggattgga atgaggtact gtataataat accaactgcg ataagaataa gcagtatacc
     9121 gatccatctt ctagaacgta cattgttata atttcttctg ggcataaagt atctaatcct
     9181 gtttcttctg aaatttctaa gtctatttta gcataaaaat gtataaaaga cggtactgaa
     9241 tgatatgttt aataaaaagt ttagttgagt ataagcagag gctagcaaga tttttcaaaa
     9301 aattcttgac ttagagttaa ctctaaggta tataataaaa ttgtaaatag tttatttttt
     9361 gatgaatgtg gagcatcatc tttttaatag agaaagaaac aataagatga aagcagcagt
     9421 ttttgtagaa ccagaaaaaa tggaggtcag agaggttgct cgtccaggtg cggttgttgg
     9481 tcgtgtcgga gtgccacata caggagacat caatattggt gactattgga tggtcaactt
     9541 ggcaatgact ggtggacctg cttcttgtac aacttatgat aaagaagtct tgttaaaagc
     9601 agttctaggc ggccaaatca atcctggtaa agttttcact taatcttaca aattggaaaa
     9661 cattgaccaa gcctacaaag atatggctga tagaaaaacg attaaagcta tgattgtgat
     9721 gtaaaataaa atgaactact gaatttttgg ggtagttcgt tttattttat gtctataatt
     9781 gatagactga gactatcgtc ttgcaggatt atttgaattt ttaaaaaatt tgtctctttt
     9841 ttatcctaca acaattacga gaattccctc taaaacaaga agcaaaagag aagtcatctt
     9901 aaaagatttc ataaagttta cctccattca tttctttcta tgatataatt ttgttaaaga
     9961 tactataaaa aattcccgta tatgaagctg gaggtttaaa atgactcatt ttggaaaaat
    10021 ttttaaaaaa tttcgtcaat ctagaggaat aaagttaaaa gacgttgcga aacatggtct
    10081 atcaaagtct caattatcta gatttgaacg tggagaaact gatttaacaa ttacaaagtt
    10141 tataagagca ttgcaggtaa taaatatgcc aattgatgaa tttatgtatg ctgtacatga
    10201 ttttcgtaga gatgaactaa atgaattgtt ggaaagaatt agagtatata ttacaacaag
    10261 agatatattg aatttgaaaa agttattgat tgaacaacaa gaaaagattc ctgaacatca
    10321 aatatttcat gaattaaata ttattttaat taaaattaaa cttcaagata tatctggaga
    10381 agatagtgtg tcagaacagg atatcaaaca tctaatagat tatttattta gtgtagaatt
    10441 ttggggaaac tatgaaatac ttcttttcgc aaatacttta gatgttttta atcatgaaac
    10501 ttttatggta ttatcccgag aaatggttag acgttcggat ttttataaag aaattcctaa
    10561 taatcgtaga attatatcta cgttgctctt aaactcttac atcacatgca tagaacgatg
    10621 cgagttaatg gatgctgttt attttgaaaa acagttaaag gcttgcttct ttattgagac
    10681 agaaatttat gaaaggttag tatttcaata tgcaaaagaa ttgtacaagt tgaagaagac
    10741 aaatgataca cgttcaatta ttgaaatgaa aaagtatatt gcagctttaa aattagctgg
    10801 gagtaatgga ttagcagaga cttttgatat ccatttgacg aaactattaa aatagtcctt
    10861 tgtgaagcat atgtgggaat ttattttatt taaagtggat agaagtataa ttgaattatc
    10921 aaataaggag tatattgtca tgaaacttga tatgaagcca aatcagaagc ttgatttatc
    10981 agtcaagaaa gttgatttaa gtgttgctgt actgacacgt gatagttcaa aagctcacgg
    11041 acactagaaa taagggtagg atcgtattct tcctaccctt ttaattacac aatagtaaaa
    11101 gaaaaaggaa attaaacatg gatgaacgtt tatggttgac aaattggaat agtctttata
    11161 ttcaaaatga tattttcttt acagatgcta taaaaccagt atatgttggt tttaaaataa
    11221 gtgaaaattg taatcaaagg tgttctcatt gttgggctgg aaaaaatctg acaataaatc
    11281 attcatttga tgaaatcatt gcggctttaa ataaaataaa aattttaaat ccacttcata
    11341 taaccattac agggggagaa cccttagtac atgaacatta gttggatatt cttggctatg
    11401 ctaagaaaaa tttccccata gttgaattgt ttacgaatgc agttttattt tctgaaaaat
    11461 caataaaaaa attatccagc ttgtttgggg atttagattt tattcaagtc agtttggacg
    11521 gtcttcgaac tacttataaa aagcaacgtg gttctgatga ttttcaaaaa gtgattgaaa
    11581 atattaagtt aatagtaaaa tacaatctga atataagagt aaatatgacg attacacatt
    11641 taaacataga agaaatgatt gatgtttatg agctagtcga tagcataggt ataacttctt
    11701 tttcaatttc tccagtttat ccattgagaa gaggaaaaaa gctagtttcg ttagtagact
    11761 atactcaata tttacataaa gggaaattaa ttgaaaaaat gcatgctaaa cgtaagagcc
    11821 aaatgaattt aacggtaatt taccctatgg aagtcctctc agaaaaggca acttatactc
    11881 aagaaagcac ctattttcaa cgttttaata cagatttatt gcattggaca attgatggta
    11941 gaggagacat atttcatttt atggatcaat ttatctataa agaactgaaa gtaggtaata
    12001 tatatgaaaa tacaattgaa gaactggaag caaatgatta tactatacaa aaaaatgtat
    12061 tagaacattc aaaccaaggt ttaaaatgta tgaactgtag tttggtagaa tcttgtcccg
    12121 gatttgccta tgctaagtca tatcctgaga ttgcatttag ttacaaaagg tgtgtattta
    12181 atgaaaaaca ataatttatt gaaaatttct caagatttag gtaatgattt tgatttacct
    12241 tattatatat atactaaagt aaaaacagat accaatgaaa aagttagtgc accacttaaa
    12301 atcggactta agctaacaaa tgcttgccat tttcgatgcc cttattgttt tgtctataaa
    12361 gataatgatt atgttgattt tgataattta aaattgattt tccaaaagtt accccaactg
    12421 ccctttgaag tatatttaac tggtggcgaa gcaattcttc acccacaatt ttcggaaatt
    12481 gtagattatc ttactaattt aggaatatta gttaaactac atacaacagg ggttattaac
    12541 atgcaaagta gaaattatat tcttaataat ttaagtaagt tttcatcaat tcaaattagc
    12601 attgattcaa taaaaaattt tgataagcta cgtcctaata taatcgataa gaatccacta
    12661 gaaagaatta tctcttttgt gaaacaatgt aaagagaaaa aatataaaaa tttattggtc
    12721 aatactgtaa taagttcgtt aaatgtaaat gagttagatg aaattatgga gttttgttta
    12781 tgtcataatt tgttcaaagt gcagctgtct acaatattta caactagcaa acgattgttg
    12841 gtttcagatg aaatttatgc taaacattat aaccaaataa ttactaagta tagtaagaaa
    12901 ggactttgtt ttcaaaattc tccattttgc catccatggt catatgctat caaacataac
    12961 ctaaaatatg attctcccat gtactgccca gcacagaaaa cagagttcga aattgatatg
    13021 caggggaatg tctacccatg tccattcttg catgatgaaa ctcataaaat gggaaatttg
    13081 ctgtctgata cctttgatga agtttggaat tcaggggtta aagagttaaa taaagcatca
    13141 tggtctgaaa ataaaaaatg taaatcatgt gcattattta aggattgtgg cggaggttgt
    13201 tatgcgttag cctatgtatc ccaattaaat tatgataaga ggtgtatttt acatgaaaat
    13261 tagtaaaaat tggtttgtta gatttgagcc aaattttcaa agttctcaaa agactatatt
    13321 atataataaa ctaaatgggg atttgtatga attatctgag gtatattttg attttattaa
    13381 taatataaat caaaaaaaag agttctctat tttgatcatg aaaaaatata atattaatca
    13441 atcagatgtt gaacagatat caaaaactat attagaaaac ttaatatcat taggagttat
    13501 actaaatgac tgacattagc ataagcaatc taaaaaaggt gtttcatgga aaagtagtat
    13561 tggatattcc acagttcaca gcttctaaat cagaaattat ttctgtctta ggtgttaatg
    13621 gagctgggaa gtctaccttt atcaagacta tttcaggttt gttgctacaa gatgaagggc
    13681 aggtgaatat ttgcggttac tccaattttt ctcctaaaat tcaccaagtc actaaatttg
    13741 tcctagaaag cggtaaagga tactacgatt atcttacagc taatcaaaat attgactatt
    13801 ttctcaaact caataaagcc tcccgaagtg atttagcttt aaacattgcg gttttgtttc
    13861 agaagttgga ttttcaacaa cacgctgata cacttgtttc agaactttct caaggaacta
    13921 gacaaaagct atctttaatt attgctctgt tgtgtcgccc agaggttctt tgtctagatg
    13981 aaccgacaaa tggattagat gtgattgcaa aaaaacaatt agctcaaata ttattaggat
    14041 tgagtaaggg caagaatacg attgttctac taactacaca tgatatttcg tttgcgagag
    14101 atatttctag tagagttttg gtaatggata atggtcgaat taagaaggat gatagttttg
    14161 agcatgtttt cagtcgcaaa aatacttgga aaaaatatga aattgtttta cctctttctt
    14221 ttcagaatat aattgagcga tcatttcaga atttacatta tgttatacaa gatgaggaaa
    14281 tgattataca aactcaagag aaagatgtaa aagaccgctt actaaaagaa acagatattg
    14341 tccgatttga ggaaatagaa caggatattg aagaaatttt atacgaggtt ttatctaaat
    14401 gatgaaagat gtaaagagag aatttttgag acagatacaa gagacgatgc aatttaaatt
    14461 taatcttttc tttgctaatt tttcaatatt cattatggtt tcatcttatc tgcattattt
    14521 tgaagagtct cagaataaat ttactctttt ttgtcttctc tttacttggt attttactag
    14581 ccatagtatt acacatccaa cattttttat agaagatgat atttatgatc ggacattgat
    14641 tagtgttatt caaagtaaaa aaagtgttgt gcatgtattg ctttttaaaa tacttgttca
    14701 aatacttata gatttgataa aggctatacc gatttttttg atactctcat ttttaagtga
    14761 tataacattt ccagcctcta tagtagagat ttttgttatt gtattaattt gtctgttagt
    14821 tattttaata ttatacggtt taggtttctg tctttctagt ttttgcttga ctttgaatag
    14881 gacatctagt tttacatcgt tgttatcata tttcattctc ttttttacag gaatcttaaa
    14941 accatttgat ggctttttgg gaatacttgg acacattttt ccgttctata cattaagaga
    15001 attcattcac cgtccatcaa ttactgaagt gcttataata ctatggtatg gtgtggttta
    15061 ttggagtatt ggttttgtac tgtttcacat atttttaaaa atggcaaaaa agaagggaaa
    15121 tatttttcat gtttaacgag ttaaagagat atttttatta tagaaaacaa tacaaatttg
    15181 atagcctttg tgatgctatt tatacattga tatttattgt agggatcatc atgatttttt
    15241 cgggccaaac attattaaat attttgtatt tttatatcta ctttctagta acaaatatta
    15301 cattattagc aaatgaggag ttagaatatg agattagaac cagtcaatac gacaatttaa
    15361 taacaagtaa gtataaagtg aagcgaatat atttgagacg tattgtagct tatctagttt
    15421 ggtcctctat actctttatt atttcacttt ttgtgtcaaa cgtttttggt agtagcactc
    15481 attttgtatt tcctaaaatg agtatatttg gcgctattgt gtttgtgtca attaatttag
    15541 tgttattttt agtgttttat atgggagtga taaagttaac agaaaaattt aaacgtgtat
    15601 ccgtattatt gaattttctg aacacaattt ttttatttta ttcaggtttg gtttttccaa
    15661 catcttttga aacatttgca gatatgttaa acaaaatttt atctctggga aacaactagt
    15721 tatcaaaaag aatttcagtt ttaatttagt gttggacaat gattcacagg cataactgga
    15781 gttaggtaag gtgagttaac aacgtactaa aaataaactg aatgactata ttataaaaat
    15841 gagtaaattt aaagggcgtt ttagtcgcac tttatatttc tgtccaatag ttctcaaata
    15901 tcttaatttt tggtaaaata aaagaaaaac ggcttagaaa gagaaaagcg atgtccttaa
    15961 ctagtcaaat tattacagcc gaatttccgg atttagaaaa agtagaacaa ctcaatacag
    16021 aagcctttcc tgaggaggag cgtgcaccgc tatctgagtt gctacgctat ggagatgggg
    16081 aatattctca tttctttgcc ttttatgacg gtgatgaatt tgtcggattt gccttttcgg
    16141 tttacaatga aagagccttt tatgtcagct tttttgcgat tatgcctcat ttgcgcagtc
    16201 acggttatgg tggcaaactt attgataagt tggtggattt ttatcaaaga accatgattt
    16261 tagaagtaga acggctggat gagccttgtg ataatctgga acagcgaaaa gcccgtatgg
    16321 atttttacaa gagaaatggt tttcgctcct cacatgccta cttagaatac gacggtttaa
    16381 gttttgaaat cctttataaa ggaccgtttt ttgatgaggg agcctatcgg gacattttca
    16441 aaaagattca agaagatggc tattttgaat ttgaaatcaa acacggtcat ggaagagact
    16501 gggagtagct gagaagcccc gtcaaaattt ttaaattttt cattgctata tataaaaaac
    16561 gagctattta tgctcgtttt ttgtggtata aagtttaata aatttctggg aaaagtttcg
    16621 ctaaaatgtt aggcgtaatg ctttgaccgg gtccttctgc acaataggtg tacatgtata
    16681 tatatggctt gaaattgagt tcgatgcagg tgcagttgga ctcttttttg ctggctggaa
    16741 gcgtgctatc cgagataatt aaatccacgc cacaaactca agctcccata gcagttgcca
    16801 tttctgccgc taattccttg taggaagtgt gcatgatttc agtcacatct actgagtctc
    16861 cgccagtaga aatattagaa ttgcaccgga gaaagacttg aactcctttt ggtaagatat
    16921 cgtctgcttt ataaccttgc tgagctagca tgagtagctc gatctctcct agtttgattc
    16981 tttccaaagg agagcggtga tctcgactgc gcaggggatt ggcgtttttc gtagcgacca
    17041 attctcgaat agtgtgtcga ccgtctcctc taacgttggc tggcaaacgt aggagtaccg
    17101 cttcacattt gccatctagg acgaaaaagc agtactcggt tcctgcgata aattcctcgc
    17161 caaggacaga gctgtcttct gaaaaggcaa tttccaatgc tttttgggaa ctgtctagat
    17221 tggtaggctc ttgaaaaata gaaattccta aaccgaagtt agtggattta ggtttgatga
    17281 caatcgattt gtcctttccg aaagtagctt gtagaatagg aacatctact gctatttttt
    17341 ctaacaaatg attgatgttc acggtaaata cctgtttgtt ttctaatact tttagtctat
    17401 tataaaaatg cttagaagac aaatgtctac tacattttcc gaactttttt aaaagaaaat
    17461 gctcataatt ttagataaga tacagatttt acaaaagcga gatgttcaaa cttcgtcatt
    17521 tgcaaataac gatggcggtc ttatcttgaa aaaagaagga atttttctta taataaagtg
    17581 taagatataa ttgcgggtga gactcctgcc atgtagacaa gaaaggacga gcacttagct
    17641 cagacaagat tatgacatca gttgttgttg tagggaccca gtggggagat gaaggaaaag
    17701 gaaagattac agatttcctt tcagccaatg ccgaagtcat tgcccgctat cagggtggtg
    17761 acaatgccgg ccataccatc gtgattggcg gtaagaagta caagctgcac ctgattccat
    17821 cagggatttt cttcccagaa aaaatctctg tgattgggaa tggaatggtg gttaatccaa
    17881 aatctttggt acatgaattg gcttatttgc acgaagaagg tgttacgacg gataatcttc
    17941 ggatttcaga tcgtgctcat gttatcctac cttatcatat tgagttagac cgcttacaag
    18001 aagaagcaaa aggtgataat aaaatcggga cgactattaa gggaattggc ccagcttaca
    18061 tggacaaagc cgctcgtgtc gggattcgga ttgcagattt gctagataag gatattttca
    18121 gagaacgttt agagcgtaat ttggctgaga agaatcgtct gtttgaaaaa ctctatgaca
    18181 gcacagctat cagatttgac gatatgtttg aggaatacta tgcatatggt cagcaaatta
    18241 aacaatacgt gacagatact tctgttatct tgaatgatgc tcttgatcaa ggcaagcgag
    18301 tgctctttga aggggcgcag ggagtgatgc tagatatcga tcaaggtact tatccatttg
    18361 taacgtcatc taatcctgtt gcaggtggtg tgacgattgg ttcgggagta gggccaagta
    18421 aaatcgacaa agttgtcggg gtttgtaaag cttataccag tcgtgttggt gatggaccat
    18481 ttccaacaga attgtttgat gaagtaggca accgcattcg tgaagtaggc catgaatatg
    18541 gaacgacaac aggacgtcct cgccgtgttg gttggtttga ctcagttgtg atgcgccata
    18601 gccgccgtgt atctggaatt accaatcttt ctctcaattc gattgatgtt ttgacggggc
    18661 ttgatacagt taaaatctgt gtcgcttatg atttagatgg tgagcgcatt gattattacc
    18721 cagctagttt ggagcagctc aaacggtgca agccaatcta tgaagaattg ccgggatggt
    18781 cagaagatat tacaggtgtt cgcagtttag aagagttgcc agagaatgct cgcaactatg
    18841 tccgccgtgt cagtgaattg gtcggtgttc gtatttctac tttctctgtc ggtcctgatc
    18901 gtgaacagac aaatatcctg gaaagtgttt ggtcaagttt gtaatagaag caaacaaagc
    18961 gggtttcggc tcgcttttta ttgacgcaat aaaaaagttt aaataatgat tctctcttaa
    19021 gttaatttta agctggctag gttatactaa aatcatcaga tgaagacctc ctaactttat
    19081 ttgatagaaa tcctaaactt tttcataata atctcctgaa agccatcgaa aggtggcttt
    19141 ttttatattt tcgggtttat aacatgatat aataaatgga gaacaaagga gataaatgat
    19201 gaactttaca gatttgtcta ataaagaaca ggaaaaaata atgataagta aaattatcag
    19261 gaatttaaaa aagctaggtg gctatgcaac caaacgagag ttgctagatg ctattaaaaa
    19321 gggagaaaat acgatagatg agaatttttt tgaggaagaa aaagtgtctc aaaaaagtgg
    19381 aaaatttata aacctagtga ttacactttt gatttttctg tcaaaagttt gcttaccacg
    19441 ggttatcttt ctaaaccaaa gcaatcgact tttgaattga cagaatatag gtagaaaagt
    19501 gaaactggat gagcattttg ctagcgatat tcaacagaaa gccattcaat tttggaaaaa
    19561 tgaaaagaag tcaaaacaat tcttcaagtt atcctttgaa aaggaactaa aacattcact
    19621 agatgactca aaagaaaatt ggagagttga gttgacaaaa gctttaaaat ctatgtcacc
    19681 acaaaaattt gaaacttttg ctcgtggtct agtcaaggag atgggtatca aactagatga
    19741 aaaaattggg gttagttata ctaatgatgg tggtttagat ggttttggcg atattactag
    19801 tacagatgac ttcagaacca atcgtgtagc tatccaagca aagcattggg aaaacaaagt
    19861 tccttcttcg gagattgata aattccgtgg tgcaatggat aaatacaatg cagaatatgg
    19921 tatttttatt acaacttctg atttttcaag aagtgccact gaagcagctc gtcaagggac
    19981 tagagtcatt actttaatca atagcgagga tattgcggat ctagttgcca aatataaact
    20041 tcatgtcagg gaagtcatga cttatgaatt aggagatttt tatcatacag aggattagac
    20101 ggttaaaaga tgaactatac agttgaagaa aaagaatttt ttatgcggga ggctttgaaa
    20161 gaagcagaga ttgcgcttgc taatgatgaa attccgattg gttgtgttat tgtcaaggac
    20221 gggaaggtta tcggtcgtgg acataatgca cgtgaggaat tgcagcgagc ggtcatgcat
    20281 gcggaagtga tggcaattga gaaagccaat cagcatgagc atagctggcg tctgctggat
    20341 acgacccttt ttgtcactat tgaaccttgt gtcatgtgca gcggagcaat tgggctagca
    20401 cggattccgc aagtcatcta tggtgcaaag aatccaaaat tcggagcagc aggcagtctt
    20461 tatgacattt taacagatga acgtcttaat caccgagttg aactggaaac tgggattttg
    20521 gaggtagaat gtgctcagat gatgcaagat ttttttagaa agaggagaca gagatgaaac
    20581 gttggctaag tattttattc tttcttttga cattgttgtt tattgggttg ctgataggga
    20641 atgtagaatt tcaagcttgg gctttcacac gtcatcaaaa tcagctatct tggtatatcc
    20701 gtccgattct cattttaccg attatctatt tttcctatcg aaagagcctt cttggaattt
    20761 ctgctagcat ctttgctctt tttaccagta tgatttggtt ttgggaacca aagacgactt
    20821 ttcctttggt aaaagagttt ctaacttatg agcaagattt tttacaggca gattggaatc
    20881 ttaaaaaaat tttatttatc tttttggtga ttagtttctt tctgctcctg gttagagcaa
    20941 cttggctcca tagttggaaa ttgttggcaa tacttttgat tcttacagct tttttgaaaa
    21001 tcctctggtc ttatctagat agtgggagag ctggtttaac aattgtggtg ccagcgattc
    21061 taggtttatt tatctgttta tttttccttt ctttttggat gaagggaaaa tcttaattgg
    21121 catagaaaca aatttatggt ataatactta tcggagcaac aattctgcgt gaagcgggtc
    21181 aggggaggaa tccagcagcc ctaagcgagt gtgaattgtg tgctcttttt atggtatgaa
    21241 gaataggaac aattctaaag cgcgtgttga agaattgaaa aacttcttca aaaatagtgt
    21301 ttagttataa atcagtatca tttctgagaa aggaaaagac agatgtatta catgggagag
    21361 atttttagag aactacgaac agggaggcac ctttctctta aggaagcaac tggagaggag
    21421 ttttcatatt ctatgctcag taagtttgaa aatggaacgt cagatatttc ggcctcaaaa
    21481 ctgttaattg gtttagagaa tattagaaca gaactagaag aatttgttta tttagtacgt
    21541 ggctttcagc ctacttcata cactctacta aaaaataaac tatgggaggc tcaagaacag
    21601 aaggatataa agacgttatg ggaaatgtac aacaatgaaa tagatcaata ccaatctaaa
    21661 aaagaagagg agcatatcct aaatgctatt gttatcaaag gtcacatgtt tttcctggat
    21721 gaaaccatta aagcaacaga ggtcgagctg aattttttat atgattattt cttttctgtt
    21781 gaaatctggg gagaatatga gttgcgattg ttttcagata tagcagcttt atttcctatt
    21841 gatctctatt tccggtacac tcgagaaatg ttacaaagag ttgatttttt aggggatcta
    21901 cagaaaaata aaaattatat ctacaccatt ctcctgaatg gactgtttaa agcaattgac
    21961 aaaaaaagtt taaataaagc agcttatttt gataaaaaaa taaaagaaaa gttttttgat
    22021 gaaaatgaag cctatttgcg aattgtctat ttgttcgcag atggacagca tgattatatt
    22081 ttaggacaga gaaatgaggg gcttacaaaa atgaaaaatg ccatatcaac tcttgaaatc
    22141 atcggctgtg agcatagcgc aaattattac tctaaaaata tgtccgaatg gttaaaagaa
    22201 tttgaataaa tgacaattga aacttttttg taaaaaaaaa ttaaaacgag gaaataagtc
    22261 tatagaatta aaaatggatt gatttcctta tttttttgcc taaaaatgaa gctgagtata
    22321 tgataatttt gttttggagg ttgattctta gattttgtta aaaaccaata ttacggctta
    22381 taacgtactg attattagtt tatgatataa tggttcaaat agaagagatg taaataagaa
    22441 caagctgtaa taaaaatgtt gaggagaaat tctatgaaag aaattgatta tagtcaatgg
    22501 aaaatgaatt tattttatga agatgagaat aagaaaatat atatagatac tgcatctgag
    22561 gaaaaatata tcgtttataa gttgttttca ggtattgagg ttatgtattg taattttgtt
    22621 aacaatgagc agtggtctgt tcctgcaata tttgaagttc ctaaatactt tcaaattgct
    22681 tatagtcata atggagccct gcaacttgaa ttgaataaag gcaaaacggt ttggtgcgat
    22741 ccaggagact tatacatttt tcatgatgtt aatagaagat actattctga agttttaaca
    22801 acggattttc atggctttca tttaatcata acacctgaga cgattgattc tgaaacaagt
    22861 gcctattttc taaaatattt tgatttgaac gtagcagatt tatataagaa gattcagacc
    22921 atgaagccgg tattgaaact taaatctttt gataatgcca ttcatatttg tgaagaatta
    22981 tatgaaaata ttttagagga aatgattggg gttatacgag tgaagacaat agagctgcta
    23041 ttgcttctct atgaaacaaa tataaatcag gtacatattt ataggaattt cacgaaagaa
    23101 accatcgaaa aaacaaggat ggcgaaagcg tatatcgatg ccaatttaga gaaaaacatc
    23161 acggtagaat atttatgtat aacatttgat ttaacgctaa ctttatttaa aaattgcttt
    23221 aaagagttgt atcagcatgc tccgtatgag tattgtttaa agg
//
