LOCUS       c00056_NZ_NFJN..       10813 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_NFJN01000006.1 Gordonibacter urolithinfaciens strain An234A
            An234A_contig_6, whole genome shotgun sequence.
ACCESSION   NZ_NFJN01000006
VERSION     NZ_NFJN01000006
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 15:16:32
            Original ID  :: NZ_NFJN01000006.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 121696
            Orig. end    :: 132509
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10813
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[126696:127509](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5813)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..10813
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10813
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             complement(351..1238)
                     /gene_functions="transport (smcogs) SMCOG1166:transporter,
                     EamA family (Score: 108.8; E-value: 5.5e-33)"
                     /gene_kind="transport"
                     /locus_tag="ctg56_116"
                     /transl_table=11
                     /translation="MARILKTPASLPLWTYKAFLLVAAAIWGLGTVVIKSTVDAFPPAW
                     IVGVRFTAAGIILGVIMLPRFRKHIDAEHLRKGSVLGVMVFLAYWSNSTGLTDTTASNS
                     SFLTSLYCVIIPFLGWALHGPRPTRFNLAAAVVCVAGVGCVSFAGAAGFSLRFGDLVTL
                     LSALFLSFHVVYTAKFAPGCDMTLLTVIQFLVAGLLGLAAGLVFEPMPNFAALGADTWT
                     SLAYLAVFASCVALLLQNLAVARVDPAPASLFLATESVFGVLFSVLFPRCCSWANYLPR
                     RCLRASLSSSPASW"
     misc_feature    complement(402..404)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     PFAM_domain     complement(432..770)
                     /aSDomain="EamA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00892.22"
                     /description="EamA-like transporter family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg56_116_0002"
                     /evalue="3.10E-10"
                     /label="ctg56_116"
                     /locus_tag="ctg56_116"
                     /protein_end="269"
                     /protein_start="156"
                     /score="40.5"
                     /tool="antismash"
                     /translation="FGDLVTLLSALFLSFHVVYTAKFAPGCDMTLLTVIQFLVAGLLGL
                     AAGLVFEPMPNFAALGADTWTSLAYLAVFASCVALLLQNLAVARVDPAPASLFLATESV
                     FGVLFSVLF"
     PFAM_domain     complement(801..1184)
                     /aSDomain="EamA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00892.22"
                     /description="EamA-like transporter family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg56_116_0001"
                     /evalue="2.70E-20"
                     /label="ctg56_116"
                     /locus_tag="ctg56_116"
                     /protein_end="146"
                     /protein_start="18"
                     /score="73.0"
                     /tool="antismash"
                     /translation="FLLVAAAIWGLGTVVIKSTVDAFPPAWIVGVRFTAAGIILGVIML
                     PRFRKHIDAEHLRKGSVLGVMVFLAYWSNSTGLTDTTASNSSFLTSLYCVIIPFLGWAL
                     HGPRPTRFNLAAAVVCVAGVGCVS"
     CDS             1375..3108
                     /locus_tag="ctg56_117"
                     /transl_table=11
                     /translation="MPTFREVLRAAEITIKDNTSGRRMHEIEKILRAHHAFSGLTPEKA
                     TAILEDLGPTFVKMGQIASNRSDVIPKAYADAFKQLRANVAPVPFEVIVQTIEESLGHP
                     WRETFADIEEKPLGSASVAQVHRARLAQGPGDPVAAGAQEERPTTNAAGGGAVTAQGPV
                     VAVKVRRPNVVEQMAEDITLIRHVLALADLTHMTDGIMLTLGDLVDELARTTAEELDFT
                     VELGNLERFGAELASQPHVESPRPYPEFSTDEVLVMEYVEGAHINDLPALRAQGDDPAA
                     LGRRLAESYVTQVIDDGFFHADPHPGNILVRGEDIVWIDLGMTGTLSASERAIVGRLFA
                     SVAKNDPYALKDALLALAKAHGPVDHGLLLGQISALLDSYASIDLADINVGTALLDVIE
                     VMRTQNLTLPPSLTMLARGMVTIEGVLVDIAPETSVVEIISDHVKRQALSFDSLESKAK
                     SLLMASAASAEAATRLPTQVSHTLDMLDRGQVKVGADLHVPADFTAALYAVSGTVAMAL
                     ISAGLFVGSSLIAQTAMQPQLLGVPLLGILGYLGAFVLGVYVIWRVLLTRHQQRNDEKV
                     E"
     PFAM_domain     1615..1773
                     /aSDomain="ABC1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03109.18"
                     /description="ABC1 atypical kinase-like domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg56_117_0003"
                     /evalue="1.70E-13"
                     /label="ctg56_117"
                     /locus_tag="ctg56_117"
                     /protein_end="133"
                     /protein_start="80"
                     /score="50.4"
                     /tool="antismash"
                     /translation="LRANVAPVPFEVIVQTIEESLGHPWRETFADIEEKPLGSASVAQV
                     HRARLAQG"
     PFAM_domain     1840..2427
                     /aSDomain="ABC1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03109.18"
                     /description="ABC1 atypical kinase-like domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg56_117_0004"
                     /evalue="3.40E-44"
                     /label="ctg56_117"
                     /locus_tag="ctg56_117"
                     /protein_end="351"
                     /protein_start="155"
                     /score="150.9"
                     /tool="antismash"
                     /translation="AVTAQGPVVAVKVRRPNVVEQMAEDITLIRHVLALADLTHMTDGI
                     MLTLGDLVDELARTTAEELDFTVELGNLERFGAELASQPHVESPRPYPEFSTDEVLVME
                     YVEGAHINDLPALRAQGDDPAALGRRLAESYVTQVIDDGFFHADPHPGNILVRGEDIVW
                     IDLGMTGTLSASERAIVGRLFASVAKNDPYALK"
     CDS             3930..4763
                     /locus_tag="ctg56_118"
                     /transl_table=11
                     /translation="MSKARPNSRRNLDIAIERVSVERGDPLRLRTALANAIVGQMLPSG
                     TVKGGGALKLRYGDAATRFTRDLDTARASSIEAYIEELERNLERGWNGFTGRVVPRKPA
                     RPKNVPEGYVMQPYSIKLEYNRKPWLTVELEVGHNEIGDADAPEPIMSPDIAGVFVELG
                     FPVPDPIGLMPLHHQIAQKLHGLTEEGSARAHDLVDLQIILANSDIDLILTRKTCARLF
                     AYRNLQEWPPFIRVGEGWEALYDRQAADLNVLPSVGEAVAWANELVSRIDAAKMR"
     PFAM_domain     4065..4673
                     /aSDomain="AbiEii"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08843.13"
                     /description="Nucleotidyl transferase AbiEii toxin, Type IV
                     TA system"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg56_118_0005"
                     /evalue="1.20E-14"
                     /label="ctg56_118"
                     /locus_tag="ctg56_118"
                     /protein_end="248"
                     /protein_start="45"
                     /score="54.9"
                     /tool="antismash"
                     /translation="TVKGGGALKLRYGDAATRFTRDLDTARASSIEAYIEELERNLERG
                     WNGFTGRVVPRKPARPKNVPEGYVMQPYSIKLEYNRKPWLTVELEVGHNEIGDADAPEP
                     IMSPDIAGVFVELGFPVPDPIGLMPLHHQIAQKLHGLTEEGSARAHDLVDLQIILANSD
                     IDLILTRKTCARLFAYRNLQEWPPFIRVGEGWEALYDRQA"
     CDS             complement(5001..5813)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Linocin_M18"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg56_119"
                     /sec_met_domain="Linocin_M18 (E-value: 4e-81, bitscore:
                     264.9, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYLARESADLSAELWNRIDDTVIGTARKQLACRRFLKVFGPLGP
                     GATTVAVDGVGKEEILEDGIGRIVGRTQLELPLFYEDFTLLGRDLELAAQTGLPIDLSA
                     AVAAAKKAARREDDLVLNGSKALGADGLLTVKGSAKVKKGDWKAGENGFSDVAAAVSQL
                     AKTGYLGRYALVVAPDLFLDLQRLQPSTGMLEIDRIQKLIGDNVFMTSALAPGKAALVC
                     AEPEYMDLAVGLDLSVGYLELADFNHTFRIMETAALRVKDPAAIVVFG"
     PFAM_domain     complement(5046..5813)
                     /aSDomain="Linocin_M18"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04454.14"
                     /description="Encapsulating protein for peroxidase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg56_119_0006"
                     /evalue="3.80E-78"
                     /label="ctg56_119"
                     /locus_tag="ctg56_119"
                     /protein_end="256"
                     /protein_start="0"
                     /score="262.4"
                     /tool="antismash"
                     /translation="MDYLARESADLSAELWNRIDDTVIGTARKQLACRRFLKVFGPLGP
                     GATTVAVDGVGKEEILEDGIGRIVGRTQLELPLFYEDFTLLGRDLELAAQTGLPIDLSA
                     AVAAAKKAARREDDLVLNGSKALGADGLLTVKGSAKVKKGDWKAGENGFSDVAAAVSQL
                     AKTGYLGRYALVVAPDLFLDLQRLQPSTGMLEIDRIQKLIGDNVFMTSALAPGKAALVC
                     AEPEYMDLAVGLDLSVGYLELADFNHTFRIMETA"
     CDS             complement(6052..6426)
                     /locus_tag="ctg56_120"
                     /transl_table=11
                     /translation="MPNFPNPFSGNVDRKMTNAELMQALRIDIAGELEAIFLYEAHYLA
                     TDDPAAKAVLADIRDEEKAHMGELITLMRHLDPKETEFFLEGEGEVQEQLAELGIVTDG
                     EIAPAPETPAAAPTVGDLSE"
     PFAM_domain     complement(6190..6363)
                     /aSDomain="COQ7"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03232.15"
                     /description="Ubiquinone biosynthesis protein COQ7"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg56_120_0007"
                     /evalue="7.60E-07"
                     /label="ctg56_120"
                     /locus_tag="ctg56_120"
                     /protein_end="79"
                     /protein_start="21"
                     /score="29.1"
                     /tool="antismash"
                     /translation="MQALRIDIAGELEAIFLYEAHYLATDDPAAKAVLADIRDEEKAHM
                     GELITLMRHLDPK"
     CDS             complement(6654..7580)
                     /locus_tag="ctg56_121"
                     /transl_table=11
                     /translation="MEDTATPLAPAVPRPTPGDAAGRRAHRVAEADATAGNVPRRAGET
                     HGPVATARSRKPAVAGEARNDASTEAVSQKSSVGHRAIVRKRIAVVAGLLCLTAALAAL
                     CVRFGPELLAFVGDAPRFRAWVDDAGALGRILFVVANMAQVVLAFLPGEPLELGAGYAF
                     GFWEGTLWCLVASALGTALVMVLVRTFGMRLVGLFFPPDKIASVRWLRDARRFELLLFL
                     VFLIPGTPKDLLTYVAGLGTSPIWRIVALTTIGRIPSIVSSTLAAGALGDGNYAVAAVT
                     VVLTLALVAAGLVAYRRLATRQATEQK"
     PFAM_domain     complement(6798..7133)
                     /aSDomain="SNARE_assoc"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09335.13"
                     /description="SNARE associated Golgi protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg56_121_0008"
                     /evalue="3.50E-13"
                     /label="ctg56_121"
                     /locus_tag="ctg56_121"
                     /protein_end="261"
                     /protein_start="149"
                     /score="50.1"
                     /tool="antismash"
                     /translation="LPGEPLELGAGYAFGFWEGTLWCLVASALGTALVMVLVRTFGMRL
                     VGLFFPPDKIASVRWLRDARRFELLLFLVFLIPGTPKDLLTYVAGLGTSPIWRIVALTT
                     IGRIPSIV"
     CDS             complement(7638..9431)
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 118; E-value: 1.1e-35)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg56_122"
                     /transl_table=11
                     /translation="MRKRRARGGRQGAETAGGAPVANMPTHPGGPSGAAYPARSGRIAR
                     LRERWRNASLKTSFMGYMLVFLVAALVLSSVTASVFAALQNEVTADAYETSGLYLYDTG
                     TNALVPARSLAIDQEGNELFVQRADDGREPLPIDNPPASLLVESAQSYPYAYRVETGEG
                     GELVLEGYLADSSELSSFEGEEGIAVRDVPAYDARARKLFDEWAAKNPDNPYRAFLDTE
                     TGSDASESSQFGDLLVSPIGYYAHTVPSEDARALSTLFGLLTFLMFPLWFGACIFAAAR
                     RFYRMRLAPGFSTLDAAAAKIADQDLDFSVAYGRSDELGRLAASFEAMRTSLAASQRAL
                     WRTAEERKRLNAAFAHDLRTPLTILKGKVELLEAHLQAGDASPEQLASSAASLAAQVER
                     LERYVAAMSGLQKLEDRAVRPDAQPFDAVADAVEDIGRSLCAQAGGTRATVEAGKAPAG
                     NRGTGPHVAFALSISARCNVERPVLGVDRSLVEEVAENLVGNAARFADGRVDARLDVRD
                     GFLVLAVEDDGPGFSPAALERGCAPFFSETPSKDHFGLGLNIAALLCDKHGGDLALENR
                     AEGGARATARFALIFPAVDSQ"
     PFAM_domain     complement(7674..7967)
                     /aSDomain="HATPase_c"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02518.28"
                     /description="Histidine kinase-, DNA gyrase B-, and
                     HSP90-like ATPase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg56_122_0011"
                     /evalue="1.20E-11"
                     /label="ctg56_122"
                     /locus_tag="ctg56_122"
                     /protein_end="586"
                     /protein_start="488"
                     /score="45.1"
                     /tool="antismash"
                     /translation="LVEEVAENLVGNAARFADGRVDARLDVRDGFLVLAVEDDGPGFSP
                     AALERGCAPFFSETPSKDHFGLGLNIAALLCDKHGGDLALENRAEGGARATAR"
     PFAM_domain     complement(8190..8393)
                     /aSDomain="HisKA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00512.27"
                     /description="His Kinase A (phospho-acceptor) domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg56_122_0010"
                     /evalue="1.70E-08"
                     /label="ctg56_122"
                     /locus_tag="ctg56_122"
                     /protein_end="414"
                     /protein_start="346"
                     /score="34.5"
                     /tool="antismash"
                     /translation="RKRLNAAFAHDLRTPLTILKGKVELLEAHLQAGDASPEQLASSAA
                     SLAAQVERLERYVAAMSGLQKLE"
     PFAM_domain     complement(8433..8543)
                     /aSDomain="HAMP"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00672.27"
                     /description="HAMP domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg56_122_0009"
                     /evalue="1.00E-06"
                     /label="ctg56_122"
                     /locus_tag="ctg56_122"
                     /protein_end="333"
                     /protein_start="296"
                     /score="29.1"
                     /tool="antismash"
                     /translation="AAAAKIADQDLDFSVAYGRSDELGRLAASFEAMRTSL"
     CDS             complement(9428..10120)
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 200.4; E-value: 4.9e-61)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg56_123"
                     /transl_table=11
                     /translation="MTECERQATLLVADDEPEIVEMLQEYFVGRGFRVLTAGSGQEALE
                     QAAHGPDLVLLDVGMPRLDGFEVCRRLREHLTCPILFLTARVEDVDALEGFACGADDYV
                     LKPFSLAVLGARVDAHLARDQRQQVKTEVRFDGDLAVDYRTRTVAVAGAPVELTRREFD
                     IVAFLSKHPGQVFDRDRIHERVGGWESESDSQVVTEHIRRIRKKLAAAGAEHDPVETVW
                     GMGYRWRA"
     PFAM_domain     complement(9440..9667)
                     /aSDomain="Trans_reg_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00486.30"
                     /description="Transcriptional regulatory protein, C
                     terminal"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg56_123_0013"
                     /evalue="3.60E-22"
                     /label="ctg56_123"
                     /locus_tag="ctg56_123"
                     /protein_end="227"
                     /protein_start="151"
                     /score="78.3"
                     /tool="antismash"
                     /translation="GAPVELTRREFDIVAFLSKHPGQVFDRDRIHERVGGWESESDSQV
                     VTEHIRRIRKKLAAAGAEHDPVETVWGMGYR"
     PFAM_domain     complement(9770..10090)
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg56_123_0012"
                     /evalue="4.50E-25"
                     /label="ctg56_123"
                     /locus_tag="ctg56_123"
                     /protein_end="117"
                     /protein_start="10"
                     /score="88.1"
                     /tool="antismash"
                     /translation="LVADDEPEIVEMLQEYFVGRGFRVLTAGSGQEALEQAAHGPDLVL
                     LDVGMPRLDGFEVCRRLREHLTCPILFLTARVEDVDALEGFACGADDYVLKPFSLAVLG
                     ARV"
     CDS             complement(10266..10751)
                     /locus_tag="ctg56_124"
                     /transl_table=11
                     /translation="MLYDNIMVPYDGSESARAALAEAVRYAREDPGAALRIVQIVDTEQ
                     LVIEKLEKEGRNTTDELSSVLLHAHYDEVLAEADAALHRQIDGLLKGLMNEITVELLDE
                     TVPGEQIVAYVDEHACDLIVMGSRGLGALRGILGSVSSHVLREAAVPVLIVKQRADR"
     PFAM_domain     complement(10284..10745)
                     /aSDomain="Usp"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00582.28"
                     /description="Universal stress protein family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg56_124_0014"
                     /evalue="5.60E-25"
                     /label="ctg56_124"
                     /locus_tag="ctg56_124"
                     /protein_end="156"
                     /protein_start="2"
                     /score="88.6"
                     /tool="antismash"
                     /translation="YDNIMVPYDGSESARAALAEAVRYAREDPGAALRIVQIVDTEQLV
                     IEKLEKEGRNTTDELSSVLLHAHYDEVLAEADAALHRQIDGLLKGLMNEITVELLDETV
                     PGEQIVAYVDEHACDLIVMGSRGLGALRGILGSVSSHVLREAAVPVLIVK"
ORIGIN
        1 tctggacgcg ccgcatagcc gacgatcacc tgctggtgta ccgcatagac ggcgacgacc
       61 tgcagatcgt ggcgtgcaga agccacgccg acacaccggt gcagccgtcg taggagcctt
      121 ccttccctcc tcttcggctt gcacaaggcg gccctcctgt tcgggagggc cgccgttgct
      181 ttgtaggacg ctcggctaat cggacagggg atccgcatcg tccggcatgt gctcggttgt
      241 cggtgccgac tgcacttcga gctgcgtttt gtccgattcc gcccgtggcc ctacttgcgc
      301 atctgttccc gcgtccgcct tccgtgcggc gtgctggggc aggtactcgc tcaccacgat
      361 gccggcgaag atgagagcga agcccgcaaa caacggcgcg gtaagtagtt cgcccaggaa
      421 cagcaccgag ggaacagcac cgagaacagt acgccgaaca ctgactcggt ggccaggaac
      481 agagaggcgg gcgccgggtc cacgcgggct actgctaggt tctgcagcag cagtgcgacg
      541 caggaggcga acacggccaa atacgccaag ctcgtccacg tgtcggcgcc gagtgccgcg
      601 aagttcggca tcggttcgaa cactagcccg gccgcgaggc ccaacaggcc cgccaccaag
      661 aactggatga cggtaagcag cgtcatgtcg cacccgggcg cgaacttcgc cgtgtacacc
      721 acatggaagc tcaaaaacag ggcggacagc agcgtaacta ggtcgccgaa acgcaacgag
      781 aatccagccg cgcccgcgaa cgacacgcat cccacacccg ccacgcacac aacagcggca
      841 gcgaggttaa agcgcgtggg ccgtggcccg tgcagcgccc agcccagaaa cgggatgatg
      901 acgcagtaca gcgacgtgag gaacgagctg ttcgacgccg tggtgtcggt cagcccggtg
      961 gagttgctcc agtaggccag aaacaccatc acgcccagca cagagccctt gcgcaggtgt
     1021 tcggcatcga tgtgctttct gaagcggggc agcatgatca cgcccagaat gatgcccgcg
     1081 gctgtgaagc gcacgcccac gatccacgcg ggcgggaacg catccaccgt cgacttgatg
     1141 acgacggttc ccagccccca gatggcggca gcaaccagca agaacgcctt gtacgtccaa
     1201 agcggcagcg aagcgggtgt tttcaggatg cgggccatgg tcgctgcatc ataccacggc
     1261 tgttccgaca gggcggcgtc caggtttcag cttgctgttg aaagagggca tcagaagcct
     1321 tgcccgaacg gcgcatgcta cgatggggcg gttaccatga cgaggaggcg aaacatgccc
     1381 acgttccgcg aggtgctgcg tgcggccgag atcaccatca aagacaacac gtccggtcgc
     1441 cgcatgcatg agatagagaa gatactccgc gcccatcacg cgttctccgg cctgacgccc
     1501 gagaaggcca cggccattct cgaggatctg ggacccacat tcgtgaagat ggggcagatc
     1561 gcttcgaatc gcagcgatgt cattcccaaa gcctatgccg atgcgttcaa gcagctgcgc
     1621 gccaacgtgg cgcccgtgcc gttcgaggtg atcgtgcaga cgatcgagga atcgctcggg
     1681 cacccatggc gcgagacgtt cgccgacatc gaggagaagc ccctgggctc ggcctcggta
     1741 gcgcaggtgc accgtgcccg gctggcgcaa gggccgggcg acccggtggc ggcgggcgca
     1801 caagaggagc ggcccacgac gaacgcggca ggaggcggcg ccgtaacggc gcaggggccg
     1861 gtggtggccg tgaaggtgcg ccgcccgaac gtggtggagc agatggccga ggacatcacg
     1921 ctcatccggc acgtgctggc gctggccgac ctcacgcaca tgaccgacgg catcatgctc
     1981 acgctgggcg atttggtgga cgagctggcg cgcacgacgg ccgaggagct ggatttcacc
     2041 gtggagctgg gaaacctgga gcgcttcggc gccgagctgg cgagccaacc ccatgtggag
     2101 agcccccgcc cgtaccctga gttcagcacc gatgaggtgc tggtcatgga gtacgtggag
     2161 ggcgcgcaca tcaacgacct gcccgcgctg cgcgcccagg gcgacgaccc ggccgcactc
     2221 gggcgccggc tggcggagag ctacgtgacg caggtcatcg atgacggctt cttccatgcc
     2281 gacccgcatc cgggcaacat cctcgtgcgc ggcgaggaca tcgtgtggat cgacctgggc
     2341 atgacgggca cgctctccgc ttccgagcgc gccattgtgg gccggctgtt cgcttccgtg
     2401 gcgaagaacg acccgtacgc cctgaaggac gcgttgctgg cgttggcgaa ggcgcatggc
     2461 ccggtggacc acggcctgct gcttggccag ataagcgcgc tgctggattc gtatgcgtcg
     2521 atcgacctgg cggacatcaa cgtgggcacg gcgctgctcg acgtcataga ggtcatgcgc
     2581 acgcagaacc tcacgctgcc gccttcgctc accatgctcg cgcgcggcat ggtgaccatc
     2641 gagggcgtgc tggtggacat cgcgccggaa acgagcgtgg tggagatcat ctccgaccac
     2701 gtgaagcggc aggcgctcag cttcgattcc ttggaatcga aggcgaagag cctgctcatg
     2761 gcctcggccg cttccgccga ggcggcgacg cggcttccta cgcaggtgtc gcacacgctg
     2821 gacatgctcg atcgcggcca ggtgaaggtg ggcgccgacc tgcacgtgcc ggcggacttc
     2881 acggcggcgc tctacgcggt gagcggtacc gtggccatgg cgctgatctc ggccggcctc
     2941 ttcgtgggct cgagcctcat cgcccagacg gccatgcagc cccagctgct gggcgtgccc
     3001 ctgctgggca tcctcgggta cctgggcgcg ttcgtgctgg gcgtctacgt catctggcgc
     3061 gtcctgctga cccgccacca gcagcgcaac gacgagaaag tggagtaggg ggttccgccg
     3121 gctttgcgtg cggatgtcgt gcagggctca tcaaccactt cgcaaaattt cgtcgcctgc
     3181 acggtaccgg tgggaaaagc cggcgactga gagagtagag gggggccctc cggagaatag
     3241 gttcgttgcg gggacggaga cggacttttg ctttcctgct accctaaagg agcgggcttc
     3301 ggttgcttgc agcggtcgcc aaggtggtct cggcactttg ttgaacgagg ggagttatta
     3361 tccaaagtgt caaaaccctc ccaaatgtgg tagggttttg acatgacaaa gtttgatgac
     3421 ctatatgaag cggcaataga caactacggt ttgataaccg ctgccgaagc gcgagccatg
     3481 ggcatcctgg acaaggagct tgccaggtat tccaaaagag gctggcttga gcgccgaggc
     3541 cacggactgt accggctagc acggcatgtt ccccataagc tcgaccctta tgccgaggct
     3601 gtcgccctcg tcggccccgg atcggtcata tggggtgagt cggtgcttgc gatgggcgac
     3661 cttgcgtcgg tgaatccggg aaaggtgacc gtggcaactc ctcggcgtgt ccgaagaaag
     3721 ctgccggagt ggatagaggt gatcaggctt ccaaaagggg ctcgtgtggg gtggtacgag
     3781 gatattccca gccaaccaat tgccgatgct atccgttcct gtgcaacttc ggtgatggga
     3841 gaaaggcttg cgcaagcggt caatgacgcg agaggggcgg ggctcattcg agcgtccgag
     3901 gcggaagatc tcaagaggga gctgagccta tgagcaaagc caggcctaac agccgaagga
     3961 acctcgacat agcgatagag agagtgtcgg ttgaacgtgg agaccccctt cgcctccgga
     4021 cagcgctggc aaacgccatt gtcggtcaga tgcttcccag cggcacggtg aagggcggag
     4081 gagcgttgaa gttgcgttac ggggatgccg ccacccggtt cacgagagat ctggacacgg
     4141 cccgggcgtc cagcatcgaa gcctacatcg aagagctgga gaggaacctc gaacgaggct
     4201 ggaacggatt cacggggcgg gtggtcccgc gcaagcctgc gaggccgaag aacgtgccgg
     4261 aggggtacgt catgcaaccc tatagtatca agctcgagta caaccggaag ccttggctca
     4321 cggtcgagct cgaggtggga cataatgaaa ttggtgacgc agatgccccc gagccaatta
     4381 tgtcgcctga catcgctgga gtgttcgtcg agctgggatt tccggtgcct gaccccatag
     4441 gccttatgcc cttgcatcac caaatcgccc aaaagctcca tgggctcacc gaggagggaa
     4501 gcgcgcgagc ccacgacctg gtcgacctgc agatcatctt ggcgaacagc gacattgact
     4561 tgattctgac gcgaaaaaca tgcgcaagac tttttgcgta tcgcaacttg caggaatggc
     4621 ctcccttcat acgagttggg gaaggctggg aagccttgta cgatcggcag gcagcggatc
     4681 tgaacgtctt gccttccgta ggagaggctg tggcttgggc gaacgagctt gttagtagga
     4741 tagacgccgc caagatgcga tagaggggcc gtaagctgag aggctgcccc agcggctaac
     4801 ctcgcagcct acggaggggt ggaggtgggc cattccctga tcttcgcgcg cagggcccct
     4861 taaacacttg gcgaaatttc gtcgccctgc acggtaccgg tgggcaaagc cggcgactgg
     4921 gagagtagag gaggggccct cctgcgagag cccctccttt gcggccgacg tgcttttggt
     4981 aagtaggtat gcggtggagt ctacccgaac acgacgatgg cggcggggtc cttcacgcgc
     5041 agggcggccg tctccatgat gcggaacgtg tggttgaagt cggcgagctc caggtagcca
     5101 accgagaggt ccaggcccac ggccaggtcc atatactcgg gctcggcgca cacgagcgcg
     5161 gccttgccgg gggcgagggc gctcgtcatg aacacgttgt cgccgatgag cttctggatg
     5221 cggtcgatct ccagcatgcc ggtgctcggc tgcaggcgct gcaggtccag gaacaaatcg
     5281 ggtgcaacca ccagcgcata gcggcccagg tagccggtct tggccagctg cgaaacggcg
     5341 gcggccacgt cggagaagcc gttctcgccg gccttccaat cgcccttctt cactttcgcc
     5401 gagcccttca cggtgagcaa gccgtcagcg ccgagggcct tgctaccgtt caggacgagg
     5461 tcgtcctcgc ggcgcgcggc cttcttggcg gcggcgacgg cggcggacag gtcgatgggc
     5521 aggccggttt gcgcggcgag ctccaagtcg cgtccgagca gggtgaagtc ctcgtagaac
     5581 agcggcagct ccagctgcgt gcgtccgacg atgcggccga tgccgtcttc caagatctct
     5641 tccttgccca cgccgtcaac cgcgacggtg gtggcgccgg ggcccagcgg cccgaacacc
     5701 ttcaggaagc ggcggcaggc aagctgcttg cgcgccgtgc cgatgacggt gtcgtcgatg
     5761 cggttccaga gctctgccga caggtcggct gattctcgtg ccaagtagtc cataatgcgg
     5821 tcctttcgct catgggaaaa cgatacgcgg agcagatggc ttgcgccggg cggtcgagca
     5881 gcttgccgcg cggccgcctc gtagcaaaca aatgtttcac gtgaaacatt cggtagccgt
     5941 caggcgggcg gtcgtcggga aaaggtgccg aagcgagcgt ccggtgggag ggcgcgcccc
     6001 caggttcgaa cgagtgtttc atgtgaaacg ctcgttcgag gcaggcgttc gctactctga
     6061 caggtcgcct acggtgggag cggctgcggg cgtctcgggc gccggggcaa tctcgccgtc
     6121 cgtcacgatg ccaagctcgg ccagctgctc ctgcacctct ccctcgccct ccaggaagaa
     6181 ctccgtttcc ttggggtcca gatggcgcat gagcgtgatg agctcgccca tgtgggcctt
     6241 ctcctcgtcg cggatgtcgg ccagcacggc cttggccgcc gggtcatccg tggccaggta
     6301 gtgcgcctcg tacaggaaga tggcctcgag ctcgcctgcg atgtcgatgc gcagggcctg
     6361 catgagctcc gcgttcgtca tcttgcggtc gacgttgccg gagaacgggt tcgggaagtt
     6421 gggcatgatg gtccctctct ttcgctgtgc cgcggcggtg cggccgactg tccgaagcat
     6481 gaagcactcg gacgagcagg cgatccgccg agcggcggtt gtctctctta ccttggggga
     6541 tatggtactg cggatgtcag caaaagtctc gataaataat cttccttatt gagaacttct
     6601 ctcaataagc acaattcggc agctcgaaga aagccggcac gcgtgctgtg cggctatttc
     6661 tgctccgtag cctgccgggt agccagacgg cggtaagcca ccaagcctgc cgccacgagc
     6721 gcgagggtga gcacgacggt gacggcggcc acggcgtagt tgccgtcacc caacgcaccg
     6781 gcagccagcg tggacgagac gatggaggga atacggccta tggtggtgag ggccacgatg
     6841 cgccagatgg ggctcgttcc aagcccggcc acgtaggtga gcaggtcctt cggtgtgccg
     6901 gggatcagga ataccaggaa cagcagcagc tcgaagcggc gcgcgtcgcg cagccaccgc
     6961 accgacgcta tcttatcggg tggaaagaac agccctacga ggcgcatgcc gaaggtgcgc
     7021 accagcacca tgaccagggc ggtacccaat gcgctggcca cgaggcacca cagcgtgccc
     7081 tcccagaagc cgaatgcgta gcccgcgccc agctcaagcg gctcgcccgg aaggaacgcg
     7141 agcaccacct gcgccatgtt ggccacaaca aacagaatgc gccctagcgc cccggcgtca
     7201 tcaacccacg cgcggaaccg cggggcgtcg cccacgaacg ccagcagctc cggtccgaag
     7261 cgcacgcaga gcgccgcgag ggcggcggtg aggcacagca ggccggcgac gacggcgatg
     7321 cgcttccgta cgatcgcccg gtgcccgacg gaacttttct gcgaaaccgc ttccgtcgag
     7381 gcgtcgttgc gcgcctcgcc tgcgacggcg ggcttgcgcg acctagccgt cgcgactggt
     7441 ccgtgcgttt cgcctgcccg ccttggcacg ttgcccgccg tcgcgtccgc ctcagcgacc
     7501 cggtgcgccc ggcgccctgc ggcgtcgccg ggtgtcgggc gcgggacggc gggggccaaa
     7561 ggggtcgcgg tgtcttccat gggatgctcc gtttctcggg tgcgttcggt acgcctccga
     7621 tgctacgggg caaatatcta ctggctgtca acggcgggaa aaatcaaggc aaagcgcgcc
     7681 gtcgcccgtg cgccgccctc ggcgcggttt tccaacgcca agtcgccgcc atgcttgtcg
     7741 cagagcagcg cggcaatgtt caggcccaga ccgaagtggt ctttcgacgg cgtctcgctg
     7801 aagaatggcg cgcatccccg ctccagcgcc gcgggcgaga agccgggccc gtcgtcctct
     7861 accgcgagca cgaggaaccc atcgcgcacg tccaaccgcg cgtcaacgcg gccgtcggcg
     7921 aagcgggcgg cgttgccgac gaggttctcg gccacttcct ccaccaggga acgatcgacg
     7981 ccgagtacgg ggcgctcgac gttgcagcgc gcgctgatgg agagcgcgaa tgcgacgtgc
     8041 gggcccgtgc cccggttccc ggctggcgcc ttgcccgcct ccacggtcgc ccgggtcccg
     8101 ccggcttgcg cgcagagcga ccggccgata tcttccacgg cgtccgccac ggcatcgaac
     8161 ggctgcgcat ccggccgcac ggcgcgatcc tccagctttt gcaatccgct catggcggct
     8221 acgtaacgct ccaggcgctc cacctgcgcg gcgagcgagg ctgcagagga tgccagctgc
     8281 tcgggggacg catcgccggc ctgcaggtgc gcctccagca gctccacctt tcccttcagg
     8341 atggtgagcg gcgtgcgcag gtcgtgcgcg aacgcggcgt tcaggcgctt gcgctcctcg
     8401 gccgtgcgcc acaaggcccg ctgcgatgcg gccagcgagg tgcgcatcgc ctcgaacgat
     8461 gctgccagcc tgcccaattc gtcggagcgg ccgtatgcca cggagaagtc gaggtcctgg
     8521 tcggcgatct tcgccgccgc cgcatcgagc gtggagaagc ccggcgccag ccgcatgcgg
     8581 tagaaccgcc gcgccgccgc gaagatgcat gcgccgaacc acagcgggaa catgaggaac
     8641 gtcagcagtc cgaacagcgt ggaaagcgcc cgtgcatcct ccgagggtac cgtgtgcgcg
     8701 tagtagccta tgggcgatac gagaaggtcg ccgaactgcg atgactccga cgcatcgctc
     8761 cctgtctccg tgtcgaggaa cgcacggtac gggttatcgg ggtttttggc cgcccattcg
     8821 tcgaacagct tgcgggcgcg tgcgtcgtag gcgggaacgt cccgcaccgc gatgccctcc
     8881 tcgccctcga aggaggaaag ctcgctgctg tccgcaaggt acccttcgag aacgagctct
     8941 cccccttcgc cggtttccac ccggtacgca tacgggtagc tctgggcgct ttccaccagc
     9001 aggcttgccg gagggttgtc gatgggcaac ggctcacgcc cgtcgtcggc acgctgcacg
     9061 aacagctcgt tgccctcctg gtcgatggca agcgagcgag cgggcacgag cgcgttcgtc
     9121 ccggtatcgt acaggtagag ccccgacgtc tcgtaagcgt cggcggtcac ttcgttctgc
     9181 agcgcggcga acaccgatgc ggtgacggag gacaggacga gggccgccac caggaacacc
     9241 agcatgtagc ccatgaacga ggtcttgagc gatgcgttgc gccaccgctc gcgcaggcgg
     9301 gcgatgcgtc cggaacgtgc cgggtaggcc gcacccgacg gtccgcccgg atgcgtcggc
     9361 atgttggcga ccggggcgcc gccggccgtc tccgcgccct gccttcctcc tctggcgcgc
     9421 cgcttcctca tgcgcgccat cggtaaccca tgccccatac cgtctccacg ggatcgtgct
     9481 cggcgccggc cgcagccagc ttcttgcgga tgcgccggat gtgctccgtg accacctgcg
     9541 aatcgctctc gctctcccaa ccgcccacgc gctcgtggat gcggtcgcgg tcgaacacct
     9601 gcccgggatg cttcgacagg aacgccacga tgtcgaactc gcgccgggtg agctcgacgg
     9661 gagctcccgc caccgctacc gtgcgggtcc gatagtccac ggcaaggtcg ccgtcgaagc
     9721 gcacctccgt cttcacctgc tggcgctggt cgcgcgcgag gtgggcgtcc acccgcgcgc
     9781 ccagcacggc gagcgagaac ggcttcagca cgtagtcgtc ggccccgcag gcgaagccct
     9841 cgagcgcgtc cacgtcctcc acgcgcgccg tgagaaacag gatggggcag gtcaggtgct
     9901 cgcgcaggcg gcggcacacc tcgaacccgt ccaggcgcgg catgcccacg tccagcagca
     9961 cgaggtcggg cccgtgcgcg gcctgctcga gcgcttcctg accgcttccg gccgtgagca
    10021 cgcggaagcc ccggccgacg aagtattcct gcagcatctc cactatctcg ggctcgtcgt
    10081 cggcgaccag caacgttgcc tggcgctcgc actcggtcat agcaggttct ccttcgggat
    10141 gtcggtcggc cgctcacgtt ggagcgctcg aaggccgagc atagcacgag aatgtcgaca
    10201 aaccatcaac ggccgtgctt cctccatcgt tccgcacccc gcttcgcgca attcgggcga
    10261 aggccctacc ggtctgcgcg ctgcttcacg atgagcacgg gcacggcggc ctcgcgcagc
    10321 acgtggctgc tcacgctgcc caagatgccg cgcagggcgc ccaggccgcg cgaacccatg
    10381 acgatgaggt cgcaggcatg ctcgtcaacg taggccacga tctgctcgcc gggcaccgtc
    10441 tcgtccagaa gctcaaccgt tatctcgttc atcaggccct tcaacaggcc gtcgatctgt
    10501 cggtggagcg ccgcgtccgc ttcggcgagc acctcgtcgt agtgggcgtg cagcagcacg
    10561 gacgacagct cgtcggtggt gttgcggcct tccttctcca gtttctctat gaccaactgc
    10621 tccgtgtcga ctatctgcac gatgcgcaat gcggcccccg ggtcctcgcg ggcgtagcgc
    10681 acggcctcgg ccagcgcggc ccgcgccgat tccgatccgt cgtagggaac catgatgttg
    10741 tcgtagagca tggccgctcc tcttgccggg cgcccgtcgt gggcgcgatc acgttggctc
    10801 cagtatagca ggg
//
