LOCUS       NZ_CP012871.1           9168 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP012871.1 [Enterobacter] lignolyticus strain G5 chromosome,
            complete genome.
ACCESSION   NZ_CP012871
VERSION     NZ_CP012871.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 16:01:50
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 4554369
            Orig. end    :: 4563537
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..840)
                     /locus_tag="ctg1_4151"
                     /transl_table=11
                     /translation="VDGEVRGTVEQVFSRAVNLFIPEQNTLYTLLSPSCDNAPNSCRIA
                     LEHCDKFFRPGEQVIFYKRGITVGHDKFIDFSRCKPWLPDALCFKDSRRWQSIADLINE
                     SIKDSASLFYYQGPNAFYQEIARLLQVYRGDLLQSLKIGDDTAITTAGINLIGLGIGLT
                     PTGDDYLTGLSAILFIPDSPGRRYLDVFIDIQESGKEKTTLLSAITLREAISQRYREVI
                     HRFIFQINQNDSQNIQQVINEIKRIGSSSGCDMLYGMADALALTAYFGGKNVNQDCD"
     protocluster    1..9168
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[4558654:4559485](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4286..5116
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..9168
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..9168
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="5"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     PFAM_domain     complement(55..378)
                     /aSDomain="DUF2877"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF11392.10"
                     /description="Protein of unknown function (DUF2877)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4151_0158"
                     /evalue="2.00E-24"
                     /label="ctg1_4151"
                     /locus_tag="ctg1_4151"
                     /protein_end="262"
                     /protein_start="154"
                     /score="86.4"
                     /tool="antismash"
                     /translation="LIGLGIGLTPTGDDYLTGLSAILFIPDSPGRRYLDVFIDIQESGK
                     EKTTLLSAITLREAISQRYREVIHRFIFQINQNDSQNIQQVINEIKRIGSSSGCDMLYG
                     MADA"
     CDS             complement(940..1545)
                     /locus_tag="ctg1_4152"
                     /transl_table=11
                     /translation="MSQNELIAEFLNAAVQGQPDVLKSCLASGVDINVTNRQGRTAITL
                     ASLHKQYACVEYLISAGADINKQDETCFNPFLLSCLNNDLTLLRLVLPANPDLNCLSRF
                     GGVGITPASEKGHVEIVRELLTRTEINVNHTNFVGWTPLLEAIVLNDGGVKQQEIVRLL
                     LEHGANPHMTDKYGKTPLALAREKGYHEIAELLIQSGA"
     PFAM_domain     complement(1024..1311)
                     /aSDomain="Ank_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12796.9"
                     /description="Ankyrin repeats (3 copies)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4152_0160"
                     /evalue="7.00E-09"
                     /label="ctg1_4152"
                     /locus_tag="ctg1_4152"
                     /protein_end="174"
                     /protein_start="78"
                     /score="36.3"
                     /tool="antismash"
                     /translation="SCLNNDLTLLRLVLPANPDLNCLSRFGGVGITPASEKGHVEIVRE
                     LLTRTEINVNHTNFVGWTPLLEAIVLNDGGVKQQEIVRLLLEHGANPHMTD"
     PFAM_domain     complement(1369..1512)
                     /aSDomain="Ank_4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13637.8"
                     /description="Ankyrin repeats (many copies)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4152_0159"
                     /evalue="2.20E-10"
                     /label="ctg1_4152"
                     /locus_tag="ctg1_4152"
                     /protein_end="59"
                     /protein_start="11"
                     /score="41.0"
                     /tool="antismash"
                     /translation="NAAVQGQPDVLKSCLASGVDINVTNRQGRTAITLASLHKQYACVE
                     YLI"
     CDS             1972..2901
                     /gene_functions="regulatory (smcogs) SMCOG1031:LysR family
                     transcriptional regulator (Score: 103.7; E-value: 2e-31)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_4153"
                     /transl_table=11
                     /translation="MNSIFTEENLLTFVTAARYASFSKAAAELDLTTSAVSYTIKRIET
                     YLDVVLFVRSTRSIELTESGHYFYRKATDLLNDFHAIKRGVDTISQGIEVKLRICINQL
                     LYTPRHTAKLLQILKKQFPTCLITITTEVYNGVWESIINNHANIAIGAPGTLPDGGGID
                     YTEIGAIRWEFAIAPTHPLAFMPEPISESQLRLYPNIMVEDTALTLNKKVGWLLHGQEA
                     ILVPDFNTKCYCQILGEGVGFLPDYLVRDAKESGLLVTRQINNPRQDSLMMLAAQHTAT
                     GQVTQWIKKQFAEGGVLTEIYQDLLHQN"
     PFAM_domain     1999..2166
                     /aSDomain="HTH_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00126.29"
                     /description="Bacterial regulatory helix-turn-helix
                     protein, lysR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4153_0161"
                     /evalue="3.80E-16"
                     /label="ctg1_4153"
                     /locus_tag="ctg1_4153"
                     /protein_end="65"
                     /protein_start="9"
                     /score="58.9"
                     /tool="antismash"
                     /translation="LLTFVTAARYASFSKAAAELDLTTSAVSYTIKRIETYLDVVLFVR
                     STRSIELTESG"
     PFAM_domain     2242..2793
                     /aSDomain="LysR_substrate"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03466.22"
                     /description="LysR substrate binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4153_0162"
                     /evalue="4.60E-15"
                     /label="ctg1_4153"
                     /locus_tag="ctg1_4153"
                     /protein_end="274"
                     /protein_start="90"
                     /score="55.7"
                     /tool="antismash"
                     /translation="QGIEVKLRICINQLLYTPRHTAKLLQILKKQFPTCLITITTEVYN
                     GVWESIINNHANIAIGAPGTLPDGGGIDYTEIGAIRWEFAIAPTHPLAFMPEPISESQL
                     RLYPNIMVEDTALTLNKKVGWLLHGQEAILVPDFNTKCYCQILGEGVGFLPDYLVRDAK
                     ESGLLVTRQINNPRQDSLMML"
     CDS             3039..3989
                     /locus_tag="ctg1_4154"
                     /transl_table=11
                     /translation="MKMRFNRAMLLSFSLVFSASTLADGLQCKNKEFTLQTLGTGGPIT
                     DDQRASSGEVIWLNGKSAILIDAGGGIFLRFGQSGARLENLKLIGITHFHTDHVSDLAA
                     ILKGGYFLQQKEVIDLAGPTGGGAFPSMTQYFHDLFKKEGGAYSYLNGLYNATDGLQLE
                     SRVKDIDYTAKEPQLVYQDPEMKVTALGIPHGDVPCLAFRIETAKGTMVISADQNGSNE
                     AFVNFAKGADILVMPLAIDEHADTASKFLHAEPEAVGKIAAEINPKVLVLNHFMGKGLR
                     LKDQSVNIVKQYYHGKVYSSRDLSCFPISLASEQE"
     PFAM_domain     3228..3863
                     /aSDomain="Lactamase_B_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12706.9"
                     /description="Beta-lactamase superfamily domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4154_0163"
                     /evalue="4.90E-12"
                     /label="ctg1_4154"
                     /locus_tag="ctg1_4154"
                     /protein_end="275"
                     /protein_start="63"
                     /score="45.9"
                     /tool="antismash"
                     /translation="ILIDAGGGIFLRFGQSGARLENLKLIGITHFHTDHVSDLAAILKG
                     GYFLQQKEVIDLAGPTGGGAFPSMTQYFHDLFKKEGGAYSYLNGLYNATDGLQLESRVK
                     DIDYTAKEPQLVYQDPEMKVTALGIPHGDVPCLAFRIETAKGTMVISADQNGSNEAFVN
                     FAKGADILVMPLAIDEHADTASKFLHAEPEAVGKIAAEINPKVLVLNHF"
     CDS             3993..4313
                     /locus_tag="ctg1_4155"
                     /transl_table=11
                     /translation="MKNKIVLSITVGSMLIAGMVAPVSAEGTSYEASKTGNKAPTSSGK
                     CASGKCGTEKIYGQASLNHDPQYQLVRARDGKCGLTGEGINQQVSPQQVEDGKCTSGVC
                     GK"
     CDS             4286..5116
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_4156"
                     /sec_met_domain="DUF692 (E-value: 1.6e-83, bitscore: 278.0,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHQRRVREIAQDSAGIGLRNEHIPRLLQQPKRQDIDFLELAPDNW
                     MNIGGAKKEYLADIRKKYPLICHSLSLSIGDVCPLNETYINDIRRFLDEYRIDIYSDHL
                     CFSRDPQGYFYDLLPIPTFADALPYLTQRIDRVQNLLGRQLVLENISSYHRYTGEIPEA
                     EFWGELLQRSGCGMLLDINNVYVNAFNHNFDALDYIRSIPGNSIVYYHIAGHLEDEEFR
                     LDTHGMPVLEDVMKLAKQTFYLHGARPLLLERDNNVPPLDDLCEELADIRASIA"
     PFAM_domain     4325..5107
                     /aSDomain="DUF692"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05114.15"
                     /description="Protein of unknown function (DUF692)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4156_0164"
                     /evalue="6.50E-92"
                     /label="ctg1_4156"
                     /locus_tag="ctg1_4156"
                     /protein_end="274"
                     /protein_start="13"
                     /score="307.6"
                     /tool="antismash"
                     /translation="AGIGLRNEHIPRLLQQPKRQDIDFLELAPDNWMNIGGAKKEYLAD
                     IRKKYPLICHSLSLSIGDVCPLNETYINDIRRFLDEYRIDIYSDHLCFSRDPQGYFYDL
                     LPIPTFADALPYLTQRIDRVQNLLGRQLVLENISSYHRYTGEIPEAEFWGELLQRSGCG
                     MLLDINNVYVNAFNHNFDALDYIRSIPGNSIVYYHIAGHLEDEEFRLDTHGMPVLEDVM
                     KLAKQTFYLHGARPLLLERDNNVPPLDDLCEELADIRAS"
     CDS             5129..5866
                     /locus_tag="ctg1_4157"
                     /transl_table=11
                     /translation="VSLSPAVPASLAAAQAEFSARLRASGAADKSCTRGMTLYRNIIRE
                     NISDVLQNVFPLFCCKRDKSAVYQLVDRFVNQHHSTQPEFHQIATELLLFVREKELLSP
                     YDLALVEYEWLIYAVEIDDSEVPFPQPIRQKPARLHNVDVIPNPTLRIIALPFWLKEGE
                     PCDEEIPLHNYYAVYRKHNNEIYQKRLHLTDVHLLSGLNNQTTAVSLEQLQTQVACSFS
                     TLPLHVWLEANNNDELLSLKYRG"
     PFAM_domain     5168..5416
                     /aSDomain="DUF2063"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09836.11"
                     /description="Putative DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4157_0165"
                     /evalue="1.50E-11"
                     /label="ctg1_4157"
                     /locus_tag="ctg1_4157"
                     /protein_end="96"
                     /protein_start="13"
                     /score="44.5"
                     /tool="antismash"
                     /translation="AQAEFSARLRASGAADKSCTRGMTLYRNIIRENISDVLQNVFPLF
                     CCKRDKSAVYQLVDRFVNQHHSTQPEFHQIATELLLFV"
     CDS             5871..6467
                     /locus_tag="ctg1_4158"
                     /transl_table=11
                     /translation="MLTKLISRYTLVISSVMKADFIALLLIRLYLIPVIFAGAHAKVLG
                     FSGTVAWFAQPTAEGGLGLPFPWLLAFLATSTEVLGLICITLGLFTRIIAIPMIVVMSV
                     ASLMVHWSHGWLAIASNTMESSQRMTAFLQWLIENFPGRYNYITQLGDPVILNNGIEFS
                     ATYFIMLLVLLVYGGGRYVSTDYWLKKITPAWRSQ"
     PFAM_domain     5937..6203
                     /aSDomain="DoxX"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07681.14"
                     /description="DoxX"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4158_0166"
                     /evalue="3.60E-13"
                     /label="ctg1_4158"
                     /locus_tag="ctg1_4158"
                     /protein_end="111"
                     /protein_start="22"
                     /score="50.0"
                     /tool="antismash"
                     /translation="ALLLIRLYLIPVIFAGAHAKVLGFSGTVAWFAQPTAEGGLGLPFP
                     WLLAFLATSTEVLGLICITLGLFTRIIAIPMIVVMSVASLMVHW"
     CDS             6808..7035
                     /locus_tag="ctg1_4159"
                     /transl_table=11
                     /translation="VEQYANLNGHSGVMRYEISEDAIEIIFNDRSTYLYNAEKPGVKAV
                     AEMQRLARIGMGLETYIQRHVRSDYFRKIR"
     CDS             7175..7402
                     /locus_tag="ctg1_4160"
                     /transl_table=11
                     /translation="MEIYANKKGTSGVKAYEIAQDSITVYFKNSSVYLYNASHPGSAVV
                     AEMQKLARRGEGLNDYINQHVKADCFVLKR"
     CDS             complement(7459..8382)
                     /locus_tag="ctg1_4161"
                     /transl_table=11
                     /translation="MIHNENKHNENEYHNRSLAARKSTLVSVVVNIFLSCFQVLLGIFS
                     GSQGLIADGMHSFSDLVADFVVLTANKKSRKPSDDDHHYGHGRYENGASLIIGAILFLV
                     GAGMIWSAGGKLLHPETIANVHIIALWVALLALTAKELLFRYMLAVARRIQSSLLIANA
                     WHARSDAASSVVVAIGIFGNLLGYPWLDPVAALVVGVLIARMGYNFSADALHDLMDRSA
                     DADVEAAIKTTILAIPGVAGLHDLKTRKTGDLILVDVHIEVNGELSVREGHDIAVAVRE
                     AVMENKNVLDVMTHIDPYQGTGMPVC"
     PFAM_domain     complement(7486..7716)
                     /aSDomain="ZT_dimer"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF16916.7"
                     /description="Dimerisation domain of Zinc Transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4161_0168"
                     /evalue="1.70E-23"
                     /label="ctg1_4161"
                     /locus_tag="ctg1_4161"
                     /protein_end="299"
                     /protein_start="222"
                     /score="82.6"
                     /tool="antismash"
                     /translation="DADVEAAIKTTILAIPGVAGLHDLKTRKTGDLILVDVHIEVNGEL
                     SVREGHDIAVAVREAVMENKNVLDVMTHIDPY"
     aSDomain        complement(7486..8322)
                     /aSDomain="TIGR01297"
                     /aSTool="tigrfam"
                     /description="CDF: cation diffusion facilitator family
                     transporter"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_4161_0048"
                     /evalue="7.60E-68"
                     /identifier="TIGR01297"
                     /label="ctg1_4161"
                     /locus_tag="ctg1_4161"
                     /protein_end="299"
                     /protein_start="20"
                     /score="226.8"
                     /tool="antismash"
                     /translation="RKSTLVSVVVNIFLSCFQVLLGIFSGSQGLIADGMHSFSDLVADF
                     VVLTANKKSRKPSDDDHHYGHGRYENGASLIIGAILFLVGAGMIWSAGGKLLHPETIAN
                     VHIIALWVALLALTAKELLFRYMLAVARRIQSSLLIANAWHARSDAASSVVVAIGIFGN
                     LLGYPWLDPVAALVVGVLIARMGYNFSADALHDLMDRSADADVEAAIKTTILAIPGVAG
                     LHDLKTRKTGDLILVDVHIEVNGELSVREGHDIAVAVREAVMENKNVLDVMTHIDPY"
     PFAM_domain     complement(7729..8310)
                     /aSDomain="Cation_efflux"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01545.23"
                     /description="Cation efflux family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4161_0167"
                     /evalue="1.00E-45"
                     /label="ctg1_4161"
                     /locus_tag="ctg1_4161"
                     /protein_end="218"
                     /protein_start="24"
                     /score="156.0"
                     /tool="antismash"
                     /translation="LVSVVVNIFLSCFQVLLGIFSGSQGLIADGMHSFSDLVADFVVLT
                     ANKKSRKPSDDDHHYGHGRYENGASLIIGAILFLVGAGMIWSAGGKLLHPETIANVHII
                     ALWVALLALTAKELLFRYMLAVARRIQSSLLIANAWHARSDAASSVVVAIGIFGNLLGY
                     PWLDPVAALVVGVLIARMGYNFSADALHDLM"
     CDS             8626..9168
                     /locus_tag="ctg1_4162"
                     /transl_table=11
                     /translation="MNNTFTRGQICFHWLVFLLVVVTYAAMELKGFAAKGTPARETMAL
                     IHYTAGLSVLVLMVIRIGLKIANRDPDIIPTPPRWQIVASKALHGVLYLMFLALPVLGV
                     LTLYFGQVQWSFFSLPMPVDPVGHPELKQNMKDIHELIANAGYFIVGAHAAAALFHHYV
                     MRDNTLFRMLPWKKLQK"
     PFAM_domain     8638..9147
                     /aSDomain="Ni_hydr_CYTB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01292.22"
                     /description="Prokaryotic cytochrome b561"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4162_0169"
                     /evalue="2.20E-23"
                     /label="ctg1_4162"
                     /locus_tag="ctg1_4162"
                     /protein_end="174"
                     /protein_start="4"
                     /score="82.9"
                     /tool="antismash"
                     /translation="FTRGQICFHWLVFLLVVVTYAAMELKGFAAKGTPARETMALIHYT
                     AGLSVLVLMVIRIGLKIANRDPDIIPTPPRWQIVASKALHGVLYLMFLALPVLGVLTLY
                     FGQVQWSFFSLPMPVDPVGHPELKQNMKDIHELIANAGYFIVGAHAAAALFHHYVMRDN
                     TLFRMLP"
ORIGIN
        1 ttaatcacaa tcctggttga cattctttcc tccaaaatac gcggtcaaag caagggcgtc
       61 cgccatgccg tacagcatgt cgcagcctga acttgagccg attcgtttaa tttcgttaat
      121 aacctgttga atattctggc tatcattctg gtttatctgg aaaataaacc ggtgaataac
      181 ctcgcgatag cgctgtgaaa tagcctctcg cagcgttatt gcgctcaaca gcgtggtttt
      241 ttcttttcct gactcctgaa tatcaataaa tacgtcgagg taccgtcgcc ccgggctatc
      301 gggaataaat aaaatagcgc taagtccggt aagataatca tcacccgtcg gggtaagccc
      361 aatacctagc cctattaaat ttatccccgc cgttgtaatg gccgtatcat ccccgatttt
      421 caacgactgc aagagatcgc cgcgatatac ttgcagtagt cttgctattt cctggtaaaa
      481 ggcattcggt ccttgataat aaaataacga agcgctgtct ttgatacttt catttattaa
      541 atcagcaata ctttgccagc gccgcgaatc tttaaaacag agcgcgtcgg gcaaccaggg
      601 cttacagcgc gaaaaatcga taaatttgtc gtgacctacc gtaataccgc gtttgtaaaa
      661 gatgacctgt tcaccgggcc gaaaaaattt gtcgcagtgt tcaagcgcta tccgacagct
      721 atttggagca ttatcgcaag aagggctaag cagggtataa agtgtattct gttcgggaat
      781 aaacagattc actgcccggg aaaaaacctg ctcaacggta cctctaactt caccgtccac
      841 ttctgcctgt aatccggggc ggagagccgc cccatctgcc gtaagcgcga ggatgcactg
      901 ccgctcaaca cgtgatgcga tagtacgcct ccgggtttat caggctcctg actggatcag
      961 cagttcagca atttcgtggt accccttctc acgggccagc gccagcggcg ttttaccgta
     1021 cttatccgtc atgtgcggat tcgcgccgtg ctccaataac agcctgacga tttcctgctg
     1081 tttgacgccg ccgtcgttaa gtacgatggc ctccagcaag ggcgtccagc cgacgaaatt
     1141 ggtgtggtta acgtttattt ctgtgcgggt cagtaattca cgcacaattt ctacatgccc
     1201 cttttcgctt gccggcgtaa taccgacgcc gccaaatcgc gataaacagt tcagatcggg
     1261 gttagcgggc aataccagac gcagtaaggt taaatcgtta ttcaggcagc ttaataaaaa
     1321 agggttgaaa caggtttcat cttgtttatt aatatccgca ccggcagaaa taagatactc
     1381 aacacacgca tactgcttat gtaggctggc gagggtaatt gctgtacgtc cctggcgatt
     1441 agtaacatta atatctacgc cgctggcgag acagcttttt agtacgtctg gctggccttg
     1501 tactgctgca tttagaaact ctgcaataag ttcgttctga gacatataat aattactccc
     1561 gtacttcgtt atgccctatg aattgagaat agcaacactc aacccggttt aaaatccgtt
     1621 taagaatcat tcatcgttaa agaccctatt attgaaatat tttcaacaat gtgtgtaaga
     1681 tgtgcgttag cgcaatattt tacatgcgct aaaccgcgct ttccgggttt ttggaactta
     1741 caacaccggg tctcacgaag cctgacgggc agcggtaaga acgagttttc agaagtgtga
     1801 tgctcttcaa atgagttgta atggcggtgt taaatgtggt tcagaacgaa agcccagaac
     1861 aacgggattt caaatacatt caacaatatg gtattgcgcc gtcagcgcgg catgtcgagc
     1921 cttatcatag gttgatcgtg ctattaacta tctgcacaga ggatttgcgt aatgaactct
     1981 atttttacgg aagaaaatct tctgacgttt gtcaccgccg ctcgctacgc cagctttagc
     2041 aaagcggcag cagagctgga tctgacaaca tccgccgtca gctacaccat caaaagaata
     2101 gaaacctacc ttgatgtcgt actgtttgtg cgcagcacgc gcagtattga actcaccgaa
     2161 tcaggccact atttctatcg caaggcgacc gacctgctta acgacttcca cgccatcaaa
     2221 cgtggtgtcg acactatctc gcaagggatt gaggtgaagc tgcgcatctg catcaatcag
     2281 ctgctttaca cccctcgcca caccgcaaag ctgctgcaaa ttctgaagaa acagttcccc
     2341 acctgcctga ttaccatcac cactgaggtc tacaacggcg tatgggaatc gataattaac
     2401 aaccacgcca acatcgccat cggcgcgcca ggcacgctgc ccgacggcgg cggcatcgac
     2461 tataccgaaa ttggcgcgat ccgctgggaa ttcgccatcg ctcccactca ccctctggct
     2521 tttatgccgg aacccatttc agagagccag ctacgcctgt accccaatat catggtggaa
     2581 gataccgcgc tcacgctcaa taaaaaggtc ggttggctgc tgcacggcca ggaggccatt
     2641 ctggtacctg attttaatac caaatgctat tgccagattc tgggcgaggg ggtgggtttt
     2701 ttacccgatt acctggtgcg cgacgctaaa gaaagcggcc tgctggtaac ccggcagata
     2761 aataatccgc gtcaggactc actcatgatg ctcgccgcgc agcataccgc tacaggccag
     2821 gtcacacagt ggattaaaaa gcagtttgca gaaggagggg tgttgaccga gatttatcag
     2881 gacctgctgc accagaatta aattaccagt aaaagtggta gaagctacat aaattatctg
     2941 ttttgatgtg ttattttagt gttgtagtct tttttccttt atgttaaacg ccgtagggca
     3001 gaagagccct cgctttaatt ttcaggaaaa tcattcttat gaaaatgcgc ttcaataggg
     3061 caatgctgct gtcattttca ctggtttttt cggccagtac gctggctgac ggcctccagt
     3121 gcaaaaacaa agagttcacc ctgcaaaccc tcggtaccgg tggacctatc accgatgacc
     3181 agcgggcatc ctccggagag gtcatctggc tgaatggcaa atccgccatt ctgattgatg
     3241 ccggcggcgg aattttcctg cgctttggcc agtctggcgc ccggctggaa aatctcaaac
     3301 tcatcggcat tacccacttc cacaccgatc atgtctctga cctggccgca atccttaaag
     3361 gcggttattt tctgcagcag aaagaggtga ttgaccttgc cggaccgacg ggcggcggcg
     3421 cattcccgtc catgacgcaa tattttcatg acctgtttaa aaaagaaggc ggcgcatatt
     3481 cctatctgaa tggtctgtat aacgccaccg atgggttaca gctggaaagc cgcgttaagg
     3541 atattgacta caccgccaaa gaaccgcagt tggtttatca ggatccggaa atgaaggtca
     3601 ccgcattagg gatcccgcac ggagatgtcc cttgccttgc gtttcgtatc gaaaccgcta
     3661 agggtacgat ggtgatctcc gctgaccaaa atggcagcaa tgaagccttc gtcaattttg
     3721 cgaaaggcgc tgacattctg gtaatgccat tagcgattga tgaacacgcc gataccgcat
     3781 cgaaattcct gcacgccgaa cctgaagcgg tgggaaaaat tgctgccgaa atcaatccga
     3841 aggtactggt gctgaaccac ttcatgggca aaggtctgcg tctgaaagac cagtccgtca
     3901 atatcgtcaa gcagtactac cacgggaagg tttattccag tcgtgacctc tcctgtttcc
     3961 cgatttcatt agccagtgag caggaataat caatgaaaaa taaaattgta ttatcgatca
     4021 cggtgggctc aatgctgatt gcggggatgg ttgcgccggt ttctgctgag ggtacctcct
     4081 acgaagcgag caaaacaggc aacaaagctc ccaccagcag cggtaagtgc gccagcggta
     4141 aatgcggtac ggaaaagata tacggccagg ccagtctgaa ccatgaccca cagtaccagc
     4201 ttgtgcgcgc ccgcgatgga aaatgcggcc tgaccggtga aggtatcaat caacaggtat
     4261 cccctcaaca ggtagaggac gggaaatgca ccagcggcgt gtgcgggaaa tagcccagga
     4321 tagtgccggt atcgggctgc gtaatgaaca tatcccgcga ctgttacagc aaccaaaacg
     4381 tcaggatatc gattttctcg aactggctcc cgataactgg atgaatatag ggggcgccaa
     4441 aaaggaatac ttagcggaca taagaaaaaa gtatccttta atttgccaca gcctgagttt
     4501 gtcaatcggt gatgtgtgcc cgttaaacga aacgtacatt aacgatatcc gtcgttttct
     4561 ggatgagtac cgtatcgata tttacagcga tcatctctgc ttttcccggg acccgcaggg
     4621 atatttttac gatttactgc caataccgac gtttgccgat gcgctgccct atctgacgca
     4681 gcggatcgat cgcgtgcaga acctgctggg ccgtcagctg gttctggaaa atatttcctc
     4741 ttatcaccgc tatacgggtg agataccgga ggcagaattc tggggtgagc tattgcagcg
     4801 tagcggctgc ggcatgttac tggatattaa taatgtctac gtaaatgcct ttaatcacaa
     4861 ttttgatgcg cttgattata ttcgcagcat tccaggtaac tcgattgtgt attaccacat
     4921 cgcaggtcat ttagaagatg aggagttccg gcttgataca cacggtatgc cagtgctgga
     4981 agatgtgatg aaacttgcga agcagacgtt ttaccttcac ggcgccaggc cgctactgct
     5041 ggagcgtgat aacaacgtgc cgcctctgga tgacctctgt gaggaactgg ccgacatccg
     5101 ggcatctatt gcgtaaaaag gaggatatgt gagtctatca cctgcagtcc ctgcgtcact
     5161 ggccgccgca caggccgagt tttcagcccg gcttcgagcc agtggcgctg cggataaatc
     5221 ctgtacccgc ggcatgacgc tgtaccgaaa catcatcagg gaaaatatca gcgacgtatt
     5281 gcagaatgtt ttcccgctgt tttgctgcaa acgggataag tccgccgttt atcaactggt
     5341 cgaccggttt gtgaatcagc atcactctac tcagcctgag tttcatcaga tagcgacaga
     5401 gctgttactt ttcgtgcgtg agaaagagct gttatccccg tatgacctgg cattggtaga
     5461 atatgaatgg ctgatctacg cggttgaaat tgatgatagt gaggttcctt ttccacagcc
     5521 gataagacaa aaacccgctc gtttgcataa tgtcgatgtg atacctaacc cgacgctgag
     5581 gataatcgcc ttaccattct ggctaaaaga aggagaaccc tgtgatgagg agataccgct
     5641 tcacaattat tatgcagtct accgtaagca caataatgaa atttatcaga aaagactcca
     5701 tctgaccgat gttcatctac tttctgggct gaataatcaa acgacggcgg taagcctgga
     5761 acaattgcag acgcaggtgg catgcagttt ctccacatta cctttgcatg tatggctgga
     5821 agccaacaat aacgatgagc tgttgtcatt aaagtacagg ggataatatt atgctgacca
     5881 aattgatctc acgttacacg ctggtgatat ccagcgttat gaaagcagat ttcattgcat
     5941 tattacttat tcgtctctat ttaattcctg ttattttcgc aggggcacat gcaaaggtgc
     6001 tgggattcag tggtaccgtc gcctggtttg cacaacctac cgccgaaggc ggcctcggcc
     6061 tgccgtttcc ctggctgttg gcatttctgg ccacgtcaac tgaagtgctg ggcctgatct
     6121 gtatcacgct gggtctattt acccgcatta tagcaatccc gatgattgtc gtaatgagcg
     6181 tcgccagtct gatggttcac tggtcccatg gctggttggc cattgccagc aacaccatgg
     6241 aatccagcca gcgtatgacg gccttcctgc agtggctgat tgaaaatttc ccgggtcgtt
     6301 acaattacat cacccagctg ggcgacccgg ttattttgaa caatggcatc gaattctcag
     6361 ccacctattt catcatgttg ttggttctgc tggtttacgg tggaggacga tatgtcagca
     6421 cggactactg gctaaaaaag ataacgccag cgtggcgaag ccaataacgc ttgaccggtc
     6481 ttaacggtac tgctgctgag cgcattcacc ggcgagcgaa ccgcatatgg gctgagcaac
     6541 agcgccgcga gaaggatggc gcgttgcttc ttcggcctgc acactctcga cggaggttga
     6601 cccaacggaa atgccgatac gtcgggcagg caaaacgcca taattgcgcc cacttattaa
     6661 atctgcttaa cccgttgtta ttcgatataa aaacatctaa ttatctcgtt gtcaccgccc
     6721 acaaaaatgt gatgcgcatc acattttata atcacattcg tatagtactt tctttaggct
     6781 atgcgctgca aaaaaggaaa gttgatagtg gaacaatatg ccaacctcaa cggtcattcc
     6841 ggggtgatga ggtacgaaat ttctgaagat gcgattgaaa tcattttcaa cgatcgctcc
     6901 acctatctgt ataacgcgga aaaacccggc gtgaaggccg ttgctgaaat gcagcgactt
     6961 gcccgtattg gcatggggtt agagacctat attcaacggc acgtcagatc cgattatttt
     7021 agaaagatac ggtaacccgc acgccaggca gtggttcggt tgacccgagc cgctgccgcc
     7081 tcccgtcccg gtatcgctac gccgatcaca gcattattgt tgcttcgcta gtatttttct
     7141 tatgtcgcgt aatacacata agggaaacgc aacaatggaa atatatgcaa ataaaaaggg
     7201 tacctctggt gtgaaagcct acgaaatagc gcaggactct atcacggtat actttaaaaa
     7261 tagttcggtg tatttatata acgcctccca tccgggcagc gcggtcgttg ctgagatgca
     7321 aaaactcgcc cgccgcggcg aggggctaaa tgattatatt aaccagcatg taaaagcgga
     7381 ttgttttgtc ttaaaacgct agcacgaaaa agaagggtgt catctcagcc acccttcttt
     7441 atataacatc tggcacgttc agcaaacggg catgcctgtc ccctgatacg gatcgatgtg
     7501 ggtcatcacg tccagcacgt ttttattttc cattaccgcc tcgcgcaccg ctacggcaat
     7561 atcatgccct tcgcgcacgg aaagctcgcc gttgacctcg atatgtacat ccaccaggat
     7621 caggtcaccc gttttgcggg ttttcaggtc gtgcagcccg gcgacgccgg ggatggcgag
     7681 gatggtggtt ttgatcgccg cttccacgtc ggcatcggcc gagcggtcca tcaggtcatg
     7741 gagcgcatcg gcggaaaagt tatagcccat acgggcgatg agcacgccga ccaccagcgc
     7801 cgccaccggg tcgagccacg ggtagccgag caggttgccg aaaatcccga tggccaccac
     7861 gaccgacgac gccgcatccg aacgcgcgtg ccaggcattg gcgatcagca gcgacgactg
     7921 aatacgtctc gccaccgcca gcatgtagcg gaacagcagc tctttcgccg tcagcgcaag
     7981 cagcgcaacc cacagcgcga tgatgtgcac gttcgcaatc gtctcggggt gcagaagctt
     8041 gccgccggcg gaccaaatca tacccgcacc gaccaggaac agtatcgcgc caataattaa
     8101 cgatgccccg ttctcatagc gtccgtgacc gtagtggtgg tcgtcatcag acggtttgcg
     8161 gcttttttta ttggcggtca gcacgacaaa atcagccact aaatcggaaa acgaatgcat
     8221 accatcggct atgagcccct gcgagccgga aaatatcccc aacaggacct gaaaacaaga
     8281 cagaaatata ttcactacca cgctcaccag cgtgcttttt ctcgcagcca atgaacgatt
     8341 atgatattcg ttctcattgt gcttattttc attatgaatc atacaaaccc cagaaatatg
     8401 ccctgccgta cgacaatgcg cgtaatataa ttcaagatag cgaaaatgtg cgcgttttta
     8461 ttaaatatat ttagctcagg tttaaataag actcactttc aaaaagaaca ggttacccgg
     8521 catacctcca ccaggaataa atcagctttt atttcccaaa atgttaatgt cggcttaagc
     8581 ttttgcttat ataacgtaaa tactgcgttt tttgaggatt gactgatgaa caacacgttt
     8641 acgcgtggcc aaatctgctt tcactggctg gtatttctgc tggtcgtggt gacctacgcc
     8701 gccatggagc taaaaggttt tgccgccaaa ggtacgccag cccgggagac catggcgtta
     8761 atccactata cggcaggcct gagcgttctg gttttgatgg tgattcgtat cggccttaag
     8821 atagctaacc gcgacccgga tatcatcccg acgccgccgc gctggcaaat cgtggcgtcg
     8881 aaagcgctgc acggcgtgct gtatctgatg ttcctcgcgc tgccggtgct tggcgtgctg
     8941 acgctttatt tcggtcaggt gcagtggtcc ttcttttccc tgccgatgcc cgtcgacccg
     9001 gtaggccatc ctgaactgaa gcaaaacatg aaggatatcc acgagcttat tgctaacgcg
     9061 ggctatttta ttgtcggcgc acatgccgcc gccgcgctgt tccaccacta cgtgatgcgc
     9121 gataacacgc tattccgtat gctgccgtgg aaaaaactgc agaaatga
//
