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Overview
5.1
5.2
5.3
5.4
5.5
6.1
6.2

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_LN812102.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 5.1 | terpene | 954,948 | 974,048 |
Region 5.2 | terpene | 1,111,500 | 1,133,455 |
Region 5.3 | RRE-containing | 1,391,947 | 1,412,225 |
Region 5.4 | siderophore | 1,459,883 | 1,475,450 |
Region 5.5 | T3PKS | 1,526,714 | 1,567,769 |

NZ_LN812103.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 6.1 | RRE-containing,lassopeptide | 477,609 | 500,886 |
Region 6.2 | terpene | 940,323 | 961,303 | anacyclamide A10 | RiPP:Cyanobactin | 14%

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 5.1 | terpene | 954,948 | 974,048 |
Region 5.2 | terpene | 1,111,500 | 1,133,455 |
Region 5.3 | RRE-containing | 1,391,947 | 1,412,225 |
Region 5.4 | siderophore | 1,459,883 | 1,475,450 |
Region 5.5 | T3PKS | 1,526,714 | 1,567,769 |
Region 6.1 | RRE-containing,lassopeptide | 477,609 | 500,886 |
Region 6.2 | terpene | 940,323 | 961,303 | anacyclamide A10 | RiPP:Cyanobactin | 14%

No secondary metabolite regions were found in these records:
  NZ_LN812097.1
  NZ_LN812099.1
  NZ_LN812100.1
  NZ_LN812101.1

Compact view
NZ_LN812102.1 - Region 1 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 954,948 - 974,048 nt. (total: 19,101 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001310.1 |  | 0.20 | Terpene | naringenin | Streptomyces clavuligerus ATCC 27064
BGC0001595.1 |  | 0.16 | Alkaloid | fischerindole | Fischerella sp. SAG 46.79
BGC0000810.1 |  | 0.15 | Alkaloid | benzoxazinone DIMBOA | Zea mays
BGC0001483.1 |  | 0.15 | Other | 5-isoprenylindole-3-carboxylate β-D-glycosyl ester | Streptomyces sp. RM-5-8
BGC0002009.1 |  | 0.14 | Polyketide | kanglemycin A, kanglemycin V1, kanglemycin V2 | Amycolatopsis vancoresmycina
BGC0001140.1 |  | 0.14 | Terpene | platensimycin, platencin | Streptomyces platensis
BGC0000763.1 |  | 0.13 | Saccharide | stewartan | Pantoea stewartii subsp. stewartii DC283
BGC0001947.1 |  | 0.13 | Saccharide | K53 capsular polysaccharide | Acinetobacter baumannii
BGC0001914.1 |  | 0.13 | Other | benzastatin J, 7-hydroxyl benzastatin B, 7-hydroxyl O-demethylbenzastatin A, JBIR-67, 7-hydroxyl benzastatin F, 7-hydroxyl O-demethylbenzastatin D, O-demethylvirantmycin, 7-hydroxyl benzastatin D, virantmycin, benzastatin K, methylbenzastatin K | Streptomyces sp. RI18
BGC0001529.1 |  | 0.13 | Alkaloid | bezastatin derivates | Streptomyces sp. RI18

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001310.1 |  | 0.53 | Terpene | naringenin | Streptomyces clavuligerus ATCC 27064
BGC0001595.1 |  | 0.47 | Alkaloid | fischerindole | Fischerella sp. SAG 46.79
BGC0000810.1 |  | 0.45 | Alkaloid | benzoxazinone DIMBOA | Zea mays
BGC0001483.1 |  | 0.45 | Other | 5-isoprenylindole-3-carboxylate β-D-glycosyl ester | Streptomyces sp. RM-5-8
BGC0002009.1 |  | 0.43 | Polyketide | kanglemycin A, kanglemycin V1, kanglemycin V2 | Amycolatopsis vancoresmycina
BGC0001140.1 |  | 0.43 | Terpene | platensimycin, platencin | Streptomyces platensis
BGC0000763.1 |  | 0.42 | Saccharide | stewartan | Pantoea stewartii subsp. stewartii DC283
BGC0001947.1 |  | 0.42 | Saccharide | K53 capsular polysaccharide | Acinetobacter baumannii
BGC0001914.1 |  | 0.42 | Other | benzastatin J, 7-hydroxyl benzastatin B, 7-hydroxyl O-demethylbenzastatin A, JBIR-67, 7-hydroxyl benzastatin F, 7-hydroxyl O-demethylbenzastatin D, O-demethylvirantmycin, 7-hydroxyl benzastatin D, virantmycin, benzastatin K, methylbenzastatin K | Streptomyces sp. RI18
BGC0001529.1 |  | 0.42 | Alkaloid | bezastatin derivates | Streptomyces sp. RI18

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_LN812102.1 - Region 2 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,111,500 - 1,133,455 nt. (total: 21,956 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001458.1 |  | 0.15 | Other (Aminocoumarin) | salinipostin G | Salinispora tropica CNB-440
BGC0000903.1 |  | 0.13 | Other | fluorometabolite | Streptomyces cattleya
BGC0000663.1 |  | 0.13 | Terpene | hopene | Streptomyces coelicolor A3(2)
BGC0000670.1 |  | 0.13 | Terpene | thalianol, thaliandiol | Arabidopsis thaliana
BGC0001791.1 |  | 0.11 | NRP | sunshinamide | Gynuella sunshinyii YC6258
BGC0001000.1 |  | 0.10 | NRP, Polyketide | hectochlorin | Lyngbya majuscula
BGC0000333.1 |  | 0.08 | NRP | cyclomarin D | Salinispora arenicola CNS-205
BGC0001983.1 |  | 0.08 | Other | triacsins | Kitasatospora aureofaciens
BGC0000969.1 |  | 0.08 | NRP, Polyketide | chondramide A | Chondromyces crocatus
BGC0000433.1 |  | 0.07 | NRP | surfactin | Bacillus velezensis FZB42

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001458.1 |  | 0.45 | Other (Aminocoumarin) | salinipostin G | Salinispora tropica CNB-440
BGC0000903.1 |  | 0.42 | Other | fluorometabolite | Streptomyces cattleya
BGC0000663.1 |  | 0.42 | Terpene | hopene | Streptomyces coelicolor A3(2)
BGC0000670.1 |  | 0.41 | Terpene | thalianol, thaliandiol | Arabidopsis thaliana
BGC0001791.1 |  | 0.37 | NRP | sunshinamide | Gynuella sunshinyii YC6258
BGC0001000.1 |  | 0.35 | NRP, Polyketide | hectochlorin | Lyngbya majuscula
BGC0000333.1 |  | 0.32 | NRP | cyclomarin D | Salinispora arenicola CNS-205
BGC0001983.1 |  | 0.32 | Other | triacsins | Kitasatospora aureofaciens
BGC0000969.1 |  | 0.30 | NRP, Polyketide | chondramide A | Chondromyces crocatus
BGC0000433.1 |  | 0.29 | NRP | surfactin | Bacillus velezensis FZB42

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_LN812102.1 - Region 3 - RRE-containing
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,391,947 - 1,412,225 nt. (total: 20,279 nt) Show pHMM detection rules used
RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RRE-containing | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001551.1 |  | 0.19 | RiPP | citrulassin E | Streptomyces glaucescens
BGC0000504.1 |  | 0.15 | RiPP | cytolysin ClyLl, cytolysin ClyLs | Plasmid pAD1
BGC0000554.1 |  | 0.15 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0000500.1 |  | 0.15 | RiPP | carnolysin A1, carnolysin A2 | Carnobacterium maltaromaticum
BGC0001120.1 |  | 0.14 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0001138.1 |  | 0.14 | Other (Nucleoside) | a201a | Marinactinospora thermotolerans
BGC0000703.1 |  | 0.14 | Saccharide | kanamycin | Streptomyces kanamyceticus
BGC0000698.1 |  | 0.13 | Saccharide | hygromycin A | Streptomyces hygroscopicus
BGC0000294.1 |  | 0.13 | NRP | acinetobactin | Acinetobacter baumannii
BGC0002005.1 |  | 0.13 | RiPP | RaxX | Xanthomonas oryzae pv. oryzae

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001551.1 |  | 0.51 | RiPP | citrulassin E | Streptomyces glaucescens
BGC0000504.1 |  | 0.46 | RiPP | cytolysin ClyLl, cytolysin ClyLs | Plasmid pAD1
BGC0000554.1 |  | 0.45 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0000500.1 |  | 0.45 | RiPP | carnolysin A1, carnolysin A2 | Carnobacterium maltaromaticum
BGC0001120.1 |  | 0.43 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0001138.1 |  | 0.43 | Other (Nucleoside) | a201a | Marinactinospora thermotolerans
BGC0000703.1 |  | 0.42 | Saccharide | kanamycin | Streptomyces kanamyceticus
BGC0000698.1 |  | 0.42 | Saccharide | hygromycin A | Streptomyces hygroscopicus
BGC0000294.1 |  | 0.42 | NRP | acinetobactin | Acinetobacter baumannii
BGC0002005.1 |  | 0.42 | RiPP | RaxX | Xanthomonas oryzae pv. oryzae

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_LN812102.1 - Region 4 - siderophore
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,459,883 - 1,475,450 nt. (total: 15,568 nt) Show pHMM detection rules used
siderophore: IucA_IucC

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | siderophore | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001478.1 |  | 0.27 | Other | desferrioxamine E | Streptomyces sp. ID38640
BGC0000941.1 |  | 0.27 | Other | desferrioxamin B | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001572.1 |  | 0.26 | Other | desferrioxamine E | Pantoea agglomerans
BGC0000859.1 |  | 0.25 | Other | ectoine | Methylomicrobium alcaliphilum
BGC0000854.1 |  | 0.25 | Other | ectoine | Methylomicrobium alcaliphilum 20Z
BGC0001531.1 |  | 0.25 | Other | bisucaberin B | Tenacibaculum mesophilum
BGC0000857.1 |  | 0.25 | Other | ectoine | Methylophaga alcalica
BGC0000855.1 |  | 0.25 | Other | ectoine | Methylomicrobium kenyense
BGC0000853.1 |  | 0.25 | Other | ectoine | Streptomyces anulatus
BGC0000858.1 |  | 0.25 | Other | ectoine | Methylobacter marinus

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001478.1 |  | 0.61 | Other | desferrioxamine E | Streptomyces sp. ID38640
BGC0000941.1 |  | 0.60 | Other | desferrioxamin B | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001572.1 |  | 0.59 | Other | desferrioxamine E | Pantoea agglomerans
BGC0000859.1 |  | 0.58 | Other | ectoine | Methylomicrobium alcaliphilum
BGC0000854.1 |  | 0.58 | Other | ectoine | Methylomicrobium alcaliphilum 20Z
BGC0001531.1 |  | 0.58 | Other | bisucaberin B | Tenacibaculum mesophilum
BGC0000857.1 |  | 0.58 | Other | ectoine | Methylophaga alcalica
BGC0000855.1 |  | 0.58 | Other | ectoine | Methylomicrobium kenyense
BGC0000853.1 |  | 0.58 | Other | ectoine | Streptomyces anulatus
BGC0000858.1 |  | 0.58 | Other | ectoine | Methylobacter marinus

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_LN812102.1 - Region 5 - T3PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,526,714 - 1,567,769 nt. (total: 41,056 nt) Show pHMM detection rules used
T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | T3PKS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000282.1 |  | 0.34 | Polyketide | alkylresorcinol | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001938.1 |  | 0.32 | Polyketide | entotheonella | Candidatus Entotheonella serta
BGC0001962.1 |  | 0.32 | Polyketide | hierridin B, hierridin C | Cyanobium sp. LEGE 06113
BGC0001831.1 |  | 0.22 | Polyketide | alkylpyrone-407, alkylpyrone-393 | Myxococcus xanthus DK 1622
BGC0001927.1 |  | 0.17 | Other | A-94964 | Streptomyces sp.
BGC0001779.1 |  | 0.16 | RiPP | siamycin | Streptomyces nodosus
BGC0000521.1 |  | 0.16 | RiPP | lacticin 481 | Lactococcus lactis subsp. lactis
BGC0000539.1 |  | 0.16 | RiPP | nukacin ISK-1 | Staphylococcus warneri
BGC0000563.1 |  | 0.16 | RiPP | venezuelin | Streptomyces venezuelae ATCC 10712
BGC0000626.1 |  | 0.16 | RiPP | thuricin | Bacillus thuringiensis

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000282.1 |  | 0.67 | Polyketide | alkylresorcinol | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001938.1 |  | 0.66 | Polyketide | entotheonella | Candidatus Entotheonella serta
BGC0001962.1 |  | 0.65 | Polyketide | hierridin B, hierridin C | Cyanobium sp. LEGE 06113
BGC0001831.1 |  | 0.55 | Polyketide | alkylpyrone-407, alkylpyrone-393 | Myxococcus xanthus DK 1622
BGC0001927.1 |  | 0.48 | Other | A-94964 | Streptomyces sp.
BGC0001779.1 |  | 0.47 | RiPP | siamycin | Streptomyces nodosus
BGC0000521.1 |  | 0.47 | RiPP | lacticin 481 | Lactococcus lactis subsp. lactis
BGC0000539.1 |  | 0.47 | RiPP | nukacin ISK-1 | Staphylococcus warneri
BGC0000563.1 |  | 0.47 | RiPP | venezuelin | Streptomyces venezuelae ATCC 10712
BGC0000626.1 |  | 0.47 | RiPP | thuricin | Bacillus thuringiensis

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_LN812103.1 - Region 1 - RRE-containing,lassopeptide
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 477,609 - 500,886 nt. (total: 23,278 nt) Show pHMM detection rules used
RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])
lassopeptide: (PF13471 and Asn_synthase or micJ25 or mcjC)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Lasso peptides
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RRE-containing | lassopeptide | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | --- | ---
BGC0000575.1 |  |  | 0.61 | RiPP | lariatin | Rhodococcus jostii
BGC0000540.1 |  |  | 0.37 | RiPP | paenibacillin | Paenibacillus polymyxa OSY-DF
BGC0000543.1 |  |  | 0.33 | RiPP | pep5 | Staphylococcus epidermidis
BGC0000552.1 |  |  | 0.33 | RiPP | SmbA, SmbB | Streptococcus mutans
BGC0001173.1 |  |  | 0.32 | RiPP | plantazolicin | Bacillus pumilus ATCC 7061
BGC0001210.1 |  |  | 0.32 | RiPP | pseudomycoicidin | Bacillus pseudomycoides DSM 12442
BGC0000517.1 |  |  | 0.32 | RiPP | haloduracin β, haloduracin α | Bacillus halodurans C-125
BGC0001229.1 |  |  | 0.32 | RiPP | SBI-06990 A1, SBI-06989 A2 | Streptomyces bingchenggensis BCW-1
BGC0000518.1 |  |  | 0.32 | RiPP | informatipeptin | Streptomyces viridochromogenes DSM 40736
BGC0000513.1 |  |  | 0.32 | RiPP | Ery-9, Ery-6, Ery-8, Ery-7, Ery-5, Ery-4, Ery-3 | Saccharopolyspora erythraea NRRL 2338

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000575.1 |  | 0.64 | RiPP | lariatin | Rhodococcus jostii
BGC0000540.1 |  | 0.50 | RiPP | paenibacillin | Paenibacillus polymyxa OSY-DF
BGC0000543.1 |  | 0.50 | RiPP | pep5 | Staphylococcus epidermidis
BGC0000497.1 |  | 0.48 | RiPP | BHT-Aα, BHT-Aβ | Streptococcus ratti
BGC0000552.1 |  | 0.47 | RiPP | SmbA, SmbB | Streptococcus mutans
BGC0001173.1 |  | 0.47 | RiPP | plantazolicin | Bacillus pumilus ATCC 7061
BGC0001210.1 |  | 0.47 | RiPP | pseudomycoicidin | Bacillus pseudomycoides DSM 12442
BGC0000517.1 |  | 0.47 | RiPP | haloduracin β, haloduracin α | Bacillus halodurans C-125
BGC0001229.1 |  | 0.47 | RiPP | SBI-06990 A1, SBI-06989 A2 | Streptomyces bingchenggensis BCW-1
BGC0000518.1 |  | 0.47 | RiPP | informatipeptin | Streptomyces viridochromogenes DSM 40736

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Lasso peptide predictions
Lists the possible core peptides for each biosynthetic enzyme, including the predicted class. Each core peptide shows the leader and core peptide sequences, separated by a dash.

#### Lassopeptide(s) for ctg6_505 - Putative Class II

ctg6_505 leader / core peptide / cleaved tail
  MLELTLKGSHTEVIQLMRWIECLSTINSVTFQGDSSVKCHVKLNQLHKMPNSTVEMKTESGADIQIQLSDCEMVTL - GKKTVLRGKHYDIF

#### Lassopeptide(s) for ctg6_507 - Putative Class II

ctg6_507 leader / core peptide / cleaved tail
  MENQKQEKKEYTSPNLIVLGNIVEITF - G G A G G H D T DTYSTKYPRSE

#### Legend:

Red: Putative macrolactam
Purple: Putative cleaved off residues
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
Lasso peptides
Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists the number of disulfide bridges, possible molecular weights, and the scores for cleavage site prediction and RODEO.

ctg6_505 - Class II
  Cleavage pHMM score: -6.40
  RODEO score: 16
  Monoisotopic mass: 1642.9 Da
  Molecular weight: 1643.9 Da
  Number of bridges: 0
ctg6_507 - Class II
  Cleavage pHMM score: -1.00
  RODEO score: 27
  Monoisotopic mass: 1979.9 Da
  Molecular weight: 1981.0 Da
  Number of bridges: 0

NZ_LN812103.1 - Region 2 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 940,323 - 961,303 nt. (total: 20,981 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000472.1 |  | 0.08 | RiPP | anacyclamide A10 | Anabaena sp. 90
BGC0000565.1 |  | 0.07 | RiPP | goadsporin | Streptomyces sp. TP-A0584

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000472.1 |  | 0.30 | RiPP | anacyclamide A10 | Anabaena sp. 90
BGC0000565.1 |  | 0.29 | RiPP | goadsporin | Streptomyces sp. TP-A0584

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names