LOCUS       c00056_NZ_CABK..       11713 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CABKTP010000056.1 Clostridium polynesiense isolate
            MGYG-HGUT-01479, whole genome shotgun sequence.
ACCESSION   c00056_NZ_CABK..
VERSION     c00056_NZ_CABK..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 16:34:29
            Original ID  :: NZ_CABKTP010000056.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11713
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11713
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[348:1713](+)"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      349..1713
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..11713
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11713
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /tool="antismash"
     CDS             349..1713
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SPASM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg56_1"
                     /sec_met_domain="PF04055 (E-value: 2.5e-14, bitscore: 43.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 5.1e-17, bitscore: 52.4,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 6.4e-24, bitscore:
                     74.2, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 2.6e-09, bitscore: 27.5,
                     seeds: 166, tool: rule-based-clusters)"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 4.6e-29,
                     bitscore: 90.6, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMSLIHKFTQDEKYYIIDVNSGSVHLVDELVYDLIDEDSLKSLEE
                     LKSRLQNKYSSAEIEEGYSDIKELINEGMLYSMDLYENIAINDNSPSYIKALCLNIVHD
                     CNLRCKYCFADEGEYKGCRKPMPPEIGKRAIDWVIKKSGPRKNIEVDLFGGEPLMVFDT
                     LKEIVDYAREQEVLFNKNIRFTMTTNATLFNDEIMEYVDKNLGNIVLSIDGRKSVNDKV
                     RVKVDGSGSYDKVLPKIKSMVKLRDPEKQYYVRGTFTRNNIDFFEDVIALADEGFKEIS
                     VEPVVLPDEHELSIRKEDLPTIFTQYDKLYKEMLKRHKEDNEFKFYHFNIDLNGGPCIY
                     KRISGCGAGHEYVAITPDGDIYPCHQFVGNTDFLLGNIMDKEDINTEIPNTFKNAHIYN
                     KPKCRECWARFYCSGGCQANNFNFNGDIHIPYEIGCEMQKKRIECAIALKAQTME"
     aSDomain        361..1698
                     /aSDomain="TIGR03974"
                     /aSTool="tigrfam"
                     /description="rSAM_six_Cys: SCIFF radical SAM maturase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg56_1_0001"
                     /evalue="4.60E-198"
                     /identifier="TIGR03974"
                     /label="ctg56_1"
                     /locus_tag="ctg56_1"
                     /protein_end="450"
                     /protein_start="4"
                     /score="656.6"
                     /tool="antismash"
                     /translation="IHKFTQDEKYYIIDVNSGSVHLVDELVYDLIDEDSLKSLEELKSR
                     LQNKYSSAEIEEGYSDIKELINEGMLYSMDLYENIAINDNSPSYIKALCLNIVHDCNLR
                     CKYCFADEGEYKGCRKPMPPEIGKRAIDWVIKKSGPRKNIEVDLFGGEPLMVFDTLKEI
                     VDYAREQEVLFNKNIRFTMTTNATLFNDEIMEYVDKNLGNIVLSIDGRKSVNDKVRVKV
                     DGSGSYDKVLPKIKSMVKLRDPEKQYYVRGTFTRNNIDFFEDVIALADEGFKEISVEPV
                     VLPDEHELSIRKEDLPTIFTQYDKLYKEMLKRHKEDNEFKFYHFNIDLNGGPCIYKRIS
                     GCGAGHEYVAITPDGDIYPCHQFVGNTDFLLGNIMDKEDINTEIPNTFKNAHIYNKPKC
                     RECWARFYCSGGCQANNFNFNGDIHIPYEIGCEMQKKRIECAIALKA"
     PFAM_domain     643..1038
                     /aSDomain="Fer4_12"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13353.8"
                     /description="4Fe-4S single cluster domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg56_1_0001"
                     /evalue="6.90E-14"
                     /label="ctg56_1"
                     /locus_tag="ctg56_1"
                     /protein_end="230"
                     /protein_start="98"
                     /score="52.6"
                     /tool="antismash"
                     /translation="LNIVHDCNLRCKYCFADEGEYKGCRKPMPPEIGKRAIDWVIKKSG
                     PRKNIEVDLFGGEPLMVFDTLKEIVDYAREQEVLFNKNIRFTMTTNATLFNDEIMEYVD
                     KNLGNIVLSIDGRKSVNDKVRVKVDGSG"
     PFAM_domain     1384..1569
                     /aSDomain="SPASM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13186.8"
                     /description="Iron-sulfur cluster-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg56_1_0002"
                     /evalue="4.00E-06"
                     /label="ctg56_1"
                     /locus_tag="ctg56_1"
                     /protein_end="407"
                     /protein_start="345"
                     /score="27.3"
                     /tool="antismash"
                     /translation="CGAGHEYVAITPDGDIYPCHQFVGNTDFLLGNIMDKEDINTEIPN
                     TFKNAHIYNKPKCRECW"
     aSDomain        1384..1638
                     /aSDomain="TIGR04085"
                     /aSTool="tigrfam"
                     /description="rSAM_more_4Fe4S: radical SAM additional
                     4Fe4S-binding SPASM domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg56_1_0002"
                     /evalue="2.00E-21"
                     /identifier="TIGR04085"
                     /label="ctg56_1"
                     /locus_tag="ctg56_1"
                     /protein_end="430"
                     /protein_start="345"
                     /score="74.2"
                     /tool="antismash"
                     /translation="CGAGHEYVAITPDGDIYPCHQFVGNTDFLLGNIMDKEDINTEIPN
                     TFKNAHIYNKPKCRECWARFYCSGGCQANNFNFNGDIHIP"
     CDS             1792..3033
                     /locus_tag="ctg56_2"
                     /transl_table=11
                     /translation="MKTKARSSIIFIVTVILIATFALVGAKGLVIGGYKIKSFEELITK
                     GLDLQGGVSVLLEIVEEEVKPDELERTKELLSMRVNKIGVSETVVTTEGDRRIRIDIPG
                     MYDFQGIVETLSKTGKLVFKDPEGNELLTGNDISKATTQFDEYNKPVIGLEMNEEGRKK
                     FADATTKFVGKKISIYMDDELLTDPTVNEPITQGQAVITGNRSIEDARRIAGIINAGAL
                     PLEVSTATVRTVGPQLGANAFPNAVKAGLIGIALIFVFMIIYYRIPGILASLALTLYVI
                     LVLLAFAYIGVTMTLPGIAGLLLTIGMAVDANVLIFERIKEELSTGKSVRSSVDAGFNR
                     ALSSIMDSNITTIIAGVVLYFLGSGAVKGFALTLIIGIVLSMFTAIVVTKFLVHTALNM
                     GIINKPELFGVKRG"
     aSDomain        2179..2970
                     /aSDomain="TIGR01129"
                     /aSTool="tigrfam"
                     /description="secD: protein-export membrane protein SecD"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg56_2_0003"
                     /evalue="2.20E-98"
                     /identifier="TIGR01129"
                     /label="ctg56_2"
                     /locus_tag="ctg56_2"
                     /protein_end="393"
                     /protein_start="129"
                     /score="328.0"
                     /tool="antismash"
                     /translation="ELLTGNDISKATTQFDEYNKPVIGLEMNEEGRKKFADATTKFVGK
                     KISIYMDDELLTDPTVNEPITQGQAVITGNRSIEDARRIAGIINAGALPLEVSTATVRT
                     VGPQLGANAFPNAVKAGLIGIALIFVFMIIYYRIPGILASLALTLYVILVLLAFAYIGV
                     TMTLPGIAGLLLTIGMAVDANVLIFERIKEELSTGKSVRSSVDAGFNRALSSIMDSNIT
                     TIIAGVVLYFLGSGAVKGFALTLIIGIVLSMFTAIVVTKFLV"
     aSDomain        2260..2949
                     /aSDomain="TIGR00916"
                     /aSTool="tigrfam"
                     /description="2A0604s01: protein-export membrane protein,
                     SecD/SecF family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg56_2_0004"
                     /evalue="3.90E-72"
                     /identifier="TIGR00916"
                     /label="ctg56_2"
                     /locus_tag="ctg56_2"
                     /protein_end="386"
                     /protein_start="156"
                     /score="240.5"
                     /tool="antismash"
                     /translation="NEEGRKKFADATTKFVGKKISIYMDDELLTDPTVNEPITQGQAVI
                     TGNRSIEDARRIAGIINAGALPLEVSTATVRTVGPQLGANAFPNAVKAGLIGIALIFVF
                     MIIYYRIPGILASLALTLYVILVLLAFAYIGVTMTLPGIAGLLLTIGMAVDANVLIFER
                     IKEELSTGKSVRSSVDAGFNRALSSIMDSNITTIIAGVVLYFLGSGAVKGFALTLIIGI
                     VLSMFTAI"
     PFAM_domain     2467..2970
                     /aSDomain="SecD_SecF"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02355.18"
                     /description="Protein export membrane protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg56_2_0003"
                     /evalue="2.60E-20"
                     /label="ctg56_2"
                     /locus_tag="ctg56_2"
                     /protein_end="393"
                     /protein_start="225"
                     /score="72.7"
                     /tool="antismash"
                     /translation="VSTATVRTVGPQLGANAFPNAVKAGLIGIALIFVFMIIYYRIPGI
                     LASLALTLYVILVLLAFAYIGVTMTLPGIAGLLLTIGMAVDANVLIFERIKEELSTGKS
                     VRSSVDAGFNRALSSIMDSNITTIIAGVVLYFLGSGAVKGFALTLIIGIVLSMFTAIVV
                     TKFLV"
     CDS             3039..3896
                     /locus_tag="ctg56_3"
                     /transl_table=11
                     /translation="MLKIIEKTKLWFSLSLIVMVIGIGFLAVKGLNFGIDFKGGTQLVI
                     DMGKDFDKPEADEIIKKYDNGALTNKVENSKIEIKSNNLTEENLKKMLEELNQKYSLNE
                     KSVVSQDVIGSSIGKELTNKAYIALAIAVVLMLAYVGFRFEFKFGVAAILALVHDVIIT
                     ISIYAIFQIPINSPFIAAILTIIGYSINDTIVIFDRIRENQKIMRRKSVEEVANISITQ
                     TMRRSINTVLTTLITIVSVYIFVPTVRDFSFPLIIGIASGAYSSIFIASPIWVLLKNKR
                     KKPI"
     PFAM_domain     3111..3176
                     /aSDomain="Sec_GG"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07549.16"
                     /description="SecD/SecF GG Motif"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg56_3_0004"
                     /evalue="1.40E-08"
                     /label="ctg56_3"
                     /locus_tag="ctg56_3"
                     /protein_end="46"
                     /protein_start="24"
                     /score="34.0"
                     /tool="antismash"
                     /translation="FLAVKGLNFGIDFKGGTQLVID"
     aSDomain        3126..3848
                     /aSDomain="TIGR00966"
                     /aSTool="tigrfam"
                     /description="3a0501s07: protein-export membrane protein
                     SecF"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg56_3_0005"
                     /evalue="2.10E-73"
                     /identifier="TIGR00966"
                     /label="ctg56_3"
                     /locus_tag="ctg56_3"
                     /protein_end="270"
                     /protein_start="29"
                     /score="245.1"
                     /tool="antismash"
                     /translation="GLNFGIDFKGGTQLVIDMGKDFDKPEADEIIKKYDNGALTNKVEN
                     SKIEIKSNNLTEENLKKMLEELNQKYSLNEKSVVSQDVIGSSIGKELTNKAYIALAIAV
                     VLMLAYVGFRFEFKFGVAAILALVHDVIITISIYAIFQIPINSPFIAAILTIIGYSIND
                     TIVIFDRIRENQKIMRRKSVEEVANISITQTMRRSINTVLTTLITIVSVYIFVPTVRDF
                     SFPLIIGIASGAYSSIFIA"
     aSDomain        3255..3839
                     /aSDomain="TIGR00916"
                     /aSTool="tigrfam"
                     /description="2A0604s01: protein-export membrane protein,
                     SecD/SecF family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg56_3_0006"
                     /evalue="5.20E-54"
                     /identifier="TIGR00916"
                     /label="ctg56_3"
                     /locus_tag="ctg56_3"
                     /protein_end="267"
                     /protein_start="72"
                     /score="181.2"
                     /tool="antismash"
                     /translation="ENSKIEIKSNNLTEENLKKMLEELNQKYSLNEKSVVSQDVIGSSI
                     GKELTNKAYIALAIAVVLMLAYVGFRFEFKFGVAAILALVHDVIITISIYAIFQIPINS
                     PFIAAILTIIGYSINDTIVIFDRIRENQKIMRRKSVEEVANISITQTMRRSINTVLTTL
                     ITIVSVYIFVPTVRDFSFPLIIGIASGAYSSI"
     PFAM_domain     3333..3875
                     /aSDomain="SecD_SecF"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02355.18"
                     /description="Protein export membrane protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg56_3_0005"
                     /evalue="9.70E-65"
                     /label="ctg56_3"
                     /locus_tag="ctg56_3"
                     /protein_end="279"
                     /protein_start="98"
                     /score="217.6"
                     /tool="antismash"
                     /translation="KYSLNEKSVVSQDVIGSSIGKELTNKAYIALAIAVVLMLAYVGFR
                     FEFKFGVAAILALVHDVIITISIYAIFQIPINSPFIAAILTIIGYSINDTIVIFDRIRE
                     NQKIMRRKSVEEVANISITQTMRRSINTVLTTLITIVSVYIFVPTVRDFSFPLIIGIAS
                     GAYSSIFIASPIWVLLKN"
     CDS             4034..4894
                     /locus_tag="ctg56_4"
                     /transl_table=11
                     /translation="MHKFWQNIYRANYISGYNPFLLKNMNKALERVVKAINEREKIIIY
                     GSCDVDGICGSSLLLLVLKYLNADVEYYLPEEQSSNYYIDDYIVKNRLKILGTNLIITS
                     GCCLKNKEQEDLCRELNIDIIVTDYKSNEFKSDFITINPNEKGCSYRYKNLSASGIAFK
                     LTQALAIYYNMKCINKYIDLVLLGSCAAEVSITGENKVIFNEGLKHLRQTNNYGLKALM
                     SLNNKTSYNEMEIRELIKILTPKLNVVGRMDNARIVVELLTTSDKDRAEQIAKYLTMEL
                     KNIVS"
     PFAM_domain     4154..4594
                     /aSDomain="DHH"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01368.22"
                     /description="DHH family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg56_4_0006"
                     /evalue="1.60E-10"
                     /label="ctg56_4"
                     /locus_tag="ctg56_4"
                     /protein_end="187"
                     /protein_start="40"
                     /score="41.4"
                     /tool="antismash"
                     /translation="KIIIYGSCDVDGICGSSLLLLVLKYLNADVEYYLPEEQSSNYYID
                     DYIVKNRLKILGTNLIITSGCCLKNKEQEDLCRELNIDIIVTDYKSNEFKSDFITINPN
                     EKGCSYRYKNLSASGIAFKLTQALAIYYNMKCINKYIDLVLLG"
     CDS             4925..5041
                     /locus_tag="ctg56_5"
                     /transl_table=11
                     /translation="MDYKSKIRIIEGFPKEGISFKDITTLIEDGESLRKSVE"
     CDS             5192..5443
                     /locus_tag="ctg56_6"
                     /transl_table=11
                     /translation="VEYDLEYGKDTLEIHKDAIKPGQRVAIVDDLLATGGTIGAVAKLV
                     EQVGGVVVSMGFAIELTDLKGRDKLGKYDIMSLVQYDI"
     PFAM_domain     5228..5392
                     /aSDomain="Pribosyltran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00156.29"
                     /description="Phosphoribosyl transferase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg56_6_0007"
                     /evalue="3.30E-07"
                     /label="ctg56_6"
                     /locus_tag="ctg56_6"
                     /protein_end="67"
                     /protein_start="12"
                     /score="29.9"
                     /tool="antismash"
                     /translation="EIHKDAIKPGQRVAIVDDLLATGGTIGAVAKLVEQVGGVVVSMGF
                     AIELTDLKGR"
     CDS             5568..7742
                     /locus_tag="ctg56_7"
                     /transl_table=11
                     /translation="MIQKLMEIIDNNDYEVDKNLIVKAFNLAEDAHKTQKRESGEPYIM
                     HPLEVSCILAEMGMDSNTIAAGLLHDVIEDTNYSYEEIKKEFNEEVANLVDGVTKLGKI
                     KYKTKEEQQADNVRKMLLAMAKDIRVIIIKLADRLHNMRTLKFMPPEKQKEKSKETLDI
                     YAPLAHRLGMSKIKWELEDISFRYLNSKEYYELVSLIAEKRVEREAYISAIIEDMHKKL
                     SGSGIEADIEGRPKHFYSIYRKMVNKNKSIEQIFDLTAIRLLVESVKDCYAALGIVHTI
                     YKPLPGRFKDYIAMPKPNMYQSLHTTVIGPQGKTFEIQIRTFEMHKTAEYGIAAHWKYK
                     ETSPEGSGSNFENKLTWLRDILEWQKDTSDAVEFMEAFKIDLFSDEIFVFTPKGVVINL
                     PNEATPIDFAYKIHTDIGNRCVGAKVNGKMVTLDHKLKTGDIVEILTSAVAKGPNLDWL
                     NMVKSNQAKSKIRAWYKKAKRDENIVKGKEMLERESKKQGVNFSEVAKGDIYEKLLKRY
                     NFHNIEDVYASVGTGSLIASVVVSKLKEGIITDKPQNSDEVNKSIEDQVNKTNHNKTTN
                     VGVTVKGMDNIMVRYAKCCSPVAGDDIIGYITKGRGISIHRKDCVNIKSLPIEEKYKLV
                     EVSWGNSKGEEYISQIQIKGEDRIGLLSDIMAIISESNFHLQALNAKSVKNNIALVTIK
                     LSINSIEQLRDIMKKIRRLNGVMEVYRMHN"
     PFAM_domain     5637..6086
                     /aSDomain="HD_4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13328.8"
                     /description="HD domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg56_7_0008"
                     /evalue="7.10E-54"
                     /label="ctg56_7"
                     /locus_tag="ctg56_7"
                     /protein_end="173"
                     /protein_start="23"
                     /score="181.9"
                     /tool="antismash"
                     /translation="AFNLAEDAHKTQKRESGEPYIMHPLEVSCILAEMGMDSNTIAAGL
                     LHDVIEDTNYSYEEIKKEFNEEVANLVDGVTKLGKIKYKTKEEQQADNVRKMLLAMAKD
                     IRVIIIKLADRLHNMRTLKFMPPEKQKEKSKETLDIYAPLAHRLGM"
     aSDomain        5637..7730
                     /aSDomain="TIGR00691"
                     /aSTool="tigrfam"
                     /description="spoT_relA: RelA/SpoT family protein"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg56_7_0007"
                     /evalue="1.10E-257"
                     /identifier="TIGR00691"
                     /label="ctg56_7"
                     /locus_tag="ctg56_7"
                     /protein_end="721"
                     /protein_start="23"
                     /score="854.8"
                     /tool="antismash"
                     /translation="AFNLAEDAHKTQKRESGEPYIMHPLEVSCILAEMGMDSNTIAAGL
                     LHDVIEDTNYSYEEIKKEFNEEVANLVDGVTKLGKIKYKTKEEQQADNVRKMLLAMAKD
                     IRVIIIKLADRLHNMRTLKFMPPEKQKEKSKETLDIYAPLAHRLGMSKIKWELEDISFR
                     YLNSKEYYELVSLIAEKRVEREAYISAIIEDMHKKLSGSGIEADIEGRPKHFYSIYRKM
                     VNKNKSIEQIFDLTAIRLLVESVKDCYAALGIVHTIYKPLPGRFKDYIAMPKPNMYQSL
                     HTTVIGPQGKTFEIQIRTFEMHKTAEYGIAAHWKYKETSPEGSGSNFENKLTWLRDILE
                     WQKDTSDAVEFMEAFKIDLFSDEIFVFTPKGVVINLPNEATPIDFAYKIHTDIGNRCVG
                     AKVNGKMVTLDHKLKTGDIVEILTSAVAKGPNLDWLNMVKSNQAKSKIRAWYKKAKRDE
                     NIVKGKEMLERESKKQGVNFSEVAKGDIYEKLLKRYNFHNIEDVYASVGTGSLIASVVV
                     SKLKEGIITDKPQNSDEVNKSIEDQVNKTNHNKTTNVGVTVKGMDNIMVRYAKCCSPVA
                     GDDIIGYITKGRGISIHRKDCVNIKSLPIEEKYKLVEVSWGNSKGEEYISQIQIKGEDR
                     IGLLSDIMAIISESNFHLQALNAKSVKNNIALVTIKLSINSIEQLRDIMKKIRRLNGVM
                     EVYR"
     PFAM_domain     6264..6593
                     /aSDomain="RelA_SpoT"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04607.19"
                     /description="Region found in RelA / SpoT proteins"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg56_7_0009"
                     /evalue="1.30E-37"
                     /label="ctg56_7"
                     /locus_tag="ctg56_7"
                     /protein_end="342"
                     /protein_start="232"
                     /score="128.8"
                     /tool="antismash"
                     /translation="GRPKHFYSIYRKMVNKNKSIEQIFDLTAIRLLVESVKDCYAALGI
                     VHTIYKPLPGRFKDYIAMPKPNMYQSLHTTVIGPQGKTFEIQIRTFEMHKTAEYGIAAH
                     WKYKET"
     PFAM_domain     6726..6905
                     /aSDomain="TGS"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02824.23"
                     /description="TGS domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg56_7_0010"
                     /evalue="2.00E-23"
                     /label="ctg56_7"
                     /locus_tag="ctg56_7"
                     /protein_end="446"
                     /protein_start="386"
                     /score="82.3"
                     /tool="antismash"
                     /translation="IFVFTPKGVVINLPNEATPIDFAYKIHTDIGNRCVGAKVNGKMVT
                     LDHKLKTGDIVEILT"
     PFAM_domain     6942..7415
                     /aSDomain="DUF5913"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF19296.1"
                     /description="Domain of unknown function (DUF5913)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg56_7_0011"
                     /evalue="3.90E-12"
                     /label="ctg56_7"
                     /locus_tag="ctg56_7"
                     /protein_end="616"
                     /protein_start="458"
                     /score="46.7"
                     /tool="antismash"
                     /translation="NMVKSNQAKSKIRAWYKKAKRDENIVKGKEMLERESKKQGVNFSE
                     VAKGDIYEKLLKRYNFHNIEDVYASVGTGSLIASVVVSKLKEGIITDKPQNSDEVNKSI
                     EDQVNKTNHNKTTNVGVTVKGMDNIMVRYAKCCSPVAGDDIIGYITKGRGISIH"
     PFAM_domain     7497..7730
                     /aSDomain="ACT_4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13291.8"
                     /description="ACT domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg56_7_0012"
                     /evalue="6.00E-19"
                     /label="ctg56_7"
                     /locus_tag="ctg56_7"
                     /protein_end="721"
                     /protein_start="643"
                     /score="68.5"
                     /tool="antismash"
                     /translation="GEEYISQIQIKGEDRIGLLSDIMAIISESNFHLQALNAKSVKNNI
                     ALVTIKLSINSIEQLRDIMKKIRRLNGVMEVYR"
     CDS             7744..8211
                     /locus_tag="ctg56_8"
                     /transl_table=11
                     /translation="MEDELSMRAVIQRVKESKVLVGGEVKGSIGQGLNVLLGVAKGDSE
                     EDIKYLKDKIINLRIFEDNEGKMNLSLKDVKGELLIISQFTLYGDCRKGRRPNFMNALG
                     GEEAKKLYEIFIESCKSEGIKVETGVFGAEMDVFILNDGPVTVILESDKSF"
     aSDomain        7762..8199
                     /aSDomain="TIGR00256"
                     /aSTool="tigrfam"
                     /description="TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg56_8_0008"
                     /evalue="1.50E-57"
                     /identifier="TIGR00256"
                     /label="ctg56_8"
                     /locus_tag="ctg56_8"
                     /protein_end="152"
                     /protein_start="6"
                     /score="192.2"
                     /tool="antismash"
                     /translation="MRAVIQRVKESKVLVGGEVKGSIGQGLNVLLGVAKGDSEEDIKYL
                     KDKIINLRIFEDNEGKMNLSLKDVKGELLIISQFTLYGDCRKGRRPNFMNALGGEEAKK
                     LYEIFIESCKSEGIKVETGVFGAEMDVFILNDGPVTVILESD"
     PFAM_domain     7765..8193
                     /aSDomain="Tyr_Deacylase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02580.18"
                     /description="D-Tyr-tRNA(Tyr) deacylase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg56_8_0013"
                     /evalue="1.10E-55"
                     /label="ctg56_8"
                     /locus_tag="ctg56_8"
                     /protein_end="150"
                     /protein_start="7"
                     /score="188.1"
                     /tool="antismash"
                     /translation="RAVIQRVKESKVLVGGEVKGSIGQGLNVLLGVAKGDSEEDIKYLK
                     DKIINLRIFEDNEGKMNLSLKDVKGELLIISQFTLYGDCRKGRRPNFMNALGGEEAKKL
                     YEIFIESCKSEGIKVETGVFGAEMDVFILNDGPVTVILE"
     CDS             8225..8827
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1170:metallo-beta-lactamase family protein (Score:
                     168.3; E-value: 2.3e-51)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg56_9"
                     /transl_table=11
                     /translation="MFIKRMPAGIYAANCYIITDENTKDALVIDPGGDEDDIIDYINEK
                     GLKVQAVLVTHGHFDHVGAVRVLAEKYDVKIYINEKDHRLMEKGAGAFGDISGSDIIYI
                     GDNEVIKFGSIEIKAIETPGHSPGSMSYLVKDDLFTGDALFQMSIGRTDLEGGDFDTLI
                     SSIVEKLIILGDHINVHPGHGMSSTIQQERLYNPYLN"
     PFAM_domain     8258..8737
                     /aSDomain="Lactamase_B"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00753.29"
                     /description="Metallo-beta-lactamase superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg56_9_0014"
                     /evalue="1.40E-30"
                     /label="ctg56_9"
                     /locus_tag="ctg56_9"
                     /protein_end="171"
                     /protein_start="11"
                     /score="106.9"
                     /tool="antismash"
                     /translation="AANCYIITDENTKDALVIDPGGDEDDIIDYINEKGLKVQAVLVTH
                     GHFDHVGAVRVLAEKYDVKIYINEKDHRLMEKGAGAFGDISGSDIIYIGDNEVIKFGSI
                     EIKAIETPGHSPGSMSYLVKDDLFTGDALFQMSIGRTDLEGGDFDTLISSIVEKLI"
     CDS             8839..10287
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg56_10"
                     /sec_met_domain="PF04055 (E-value: 1.3e-24, bitscore: 77.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIDILLNNLNYRYDIYQIFNIFYSLEEISFNHDKEDYEDYKVII
                     ESDRVYISHNHMKKSYEDSENIGCKNFIKKAVFQFLTEETKEHFPWGTLVGIRPSKIAL
                     DLINKGLTAEEIISYFNRVYCTDRDKAQLCIDIAKYENSFVNNKENNISIYLGMPFCPT
                     RCAYCSFASNPISACKPLVEPYLLALKKEIEFIRDYINERKLTVETVYFGGGTPTSVDD
                     EQFKFIMKAIFDNLILNKNVKEFTVECGRPDSLSNSKLETLKKYNVTRISINPQTMNDS
                     TLKGIGRKHSSKDIIDIFNKARELGFDNINMDLIVGLPGEGLDHVRHTCSEILKLSPES
                     VTVHGMSIKRASDLHEKILLKQYYYKPNQKELNSMYNETRALAEKLNMIPYYMYRQKNM
                     VGNMENVGYTIIGRECVYNIEMIEEKQTIIALGADAVTKVVFQKDNRIERFGNLKEVKQ
                     YIDKIDAMIEGKIKLLDSLYKDNN"
     aSDomain        9046..10257
                     /aSDomain="TIGR03994"
                     /aSTool="tigrfam"
                     /description="rSAM_HemZ: coproporphyrinogen dehydrogenase
                     HemZ"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg56_10_0009"
                     /evalue="6.20E-162"
                     /identifier="TIGR03994"
                     /label="ctg56_10"
                     /locus_tag="ctg56_10"
                     /protein_end="473"
                     /protein_start="69"
                     /score="537.2"
                     /tool="antismash"
                     /translation="KNFIKKAVFQFLTEETKEHFPWGTLVGIRPSKIALDLINKGLTAE
                     EIISYFNRVYCTDRDKAQLCIDIAKYENSFVNNKENNISIYLGMPFCPTRCAYCSFASN
                     PISACKPLVEPYLLALKKEIEFIRDYINERKLTVETVYFGGGTPTSVDDEQFKFIMKAI
                     FDNLILNKNVKEFTVECGRPDSLSNSKLETLKKYNVTRISINPQTMNDSTLKGIGRKHS
                     SKDIIDIFNKARELGFDNINMDLIVGLPGEGLDHVRHTCSEILKLSPESVTVHGMSIKR
                     ASDLHEKILLKQYYYKPNQKELNSMYNETRALAEKLNMIPYYMYRQKNMVGNMENVGYT
                     IIGRECVYNIEMIEEKQTIIALGADAVTKVVFQKDNRIERFGNLKEVKQYIDKIDAMIE
                     GKIKL"
     PFAM_domain     9310..9831
                     /aSDomain="Radical_SAM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04055.23"
                     /description="Radical SAM superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg56_10_0015"
                     /evalue="2.40E-21"
                     /label="ctg56_10"
                     /locus_tag="ctg56_10"
                     /protein_end="331"
                     /protein_start="157"
                     /score="76.9"
                     /tool="antismash"
                     /translation="MPFCPTRCAYCSFASNPISACKPLVEPYLLALKKEIEFIRDYINE
                     RKLTVETVYFGGGTPTSVDDEQFKFIMKAIFDNLILNKNVKEFTVECGRPDSLSNSKLE
                     TLKKYNVTRISINPQTMNDSTLKGIGRKHSSKDIIDIFNKARELGFDNINMDLIVGLPG
                     EGLDHVRHTCS"
ORIGIN
        1 ccataaggga tgtatacaga gcaattcttg cggtaatagt gggagcgtta tcaggaatgc
       61 tgggagtgaa tatttaaaaa gtatttccag gttaaaatag ttatgctata ataatctagt
      121 acagtattag aatgggggta ttttaatgaa gcatattaga actataaaca aaaacaacat
      181 taaaaacagc ttaaaaaaac caggatgtaa agaatgcgct aactcatgcc agtcagcttg
      241 caagacttct tgtacagttg ctaatttagc ttgtgaaaac taaaaaatac cttatggggg
      301 gcagtaacta atctgttact gccttgtatt tggttgaggg ggaaaaaaat gatgtcgtta
      361 atccataaat tcactcaaga tgagaaatat tatataattg atgtaaattc aggctcagtt
      421 cacttagttg atgaactagt ttatgatctt atagatgaag atagtcttaa aagccttgaa
      481 gaattaaaaa gcagattgca aaataaatac agctccgctg aaatagaaga aggatatagt
      541 gatattaaag agcttattaa tgaaggaatg ctgtattcca tggatttata tgagaatata
      601 gctattaatg acaattcacc atcctatata aaagcccttt gcttaaatat tgtccatgac
      661 tgtaatttaa gatgtaaata ctgctttgct gatgaaggag agtataaagg ctgcagaaaa
      721 ccaatgcccc ctgaaatagg taaaagggca attgattggg ttattaaaaa aagcggtcct
      781 aggaagaata tcgaggttga tctctttgga ggagagcctt taatggtatt cgatacatta
      841 aaggaaatag tggattatgc aagagagcag gaagttttat ttaataaaaa tattagattt
      901 actatgacca ccaacgcaac tctttttaac gatgaaataa tggaatatgt tgataaaaat
      961 ctgggaaata tagtattatc aatagatgga agaaaatcag ttaacgataa ggtaagagtt
     1021 aaagtagacg gcagcggaag ttacgataaa gtacttccta agataaaatc catggttaaa
     1081 ctcagggatc cagaaaagca atattatgtt agaggaacct ttacaagaaa taatatagat
     1141 ttctttgaag atgttattgc tttagctgat gaaggtttta aagaaatatc agtggaacca
     1201 gtggttttac ctgacgaaca tgaattgtca attagaaagg aagatcttcc tactatattc
     1261 acacagtatg ataagctata taaagaaatg ctcaaaaggc ataaagaaga taacgaattt
     1321 aaattctatc atttcaatat agatttaaat ggaggaccat gtatatataa aaggatttca
     1381 ggctgcggcg caggacatga atatgttgcc attacaccgg atggagatat atatccctgt
     1441 caccaatttg taggaaatac agatttcctt ttaggaaata taatggataa agaggatata
     1501 aatacggaaa ttcctaatac ctttaaaaat gctcacatat acaataagcc aaagtgcaga
     1561 gaatgctggg cacgatttta ctgcagtgga gggtgtcaag ctaataattt taattttaat
     1621 ggagatattc acattccata tgaaataggt tgcgaaatgc agaaaaaacg tattgaatgc
     1681 gctattgcgt taaaagcaca aaccatggaa taataacgta ttttgacttt attgactaaa
     1741 aatgtaattg tatatataat ttatttaaca gcataacaga gggggataag aatgaaaaca
     1801 aaagctagaa gcagcattat attcattgtt actgtaatat taatagcaac ctttgctctt
     1861 gttggagcaa aaggcttagt aataggtgga tataaaatca aatcctttga agagttaatt
     1921 acaaaaggtc tggatttaca gggtggagta tccgttctcc ttgagatagt agaagaggag
     1981 gttaaacctg atgaacttga aagaacaaaa gaactgttaa gcatgagggt aaataagatc
     2041 ggagtcagtg aaacagtagt taccactgaa ggtgacagac gtataaggat tgacatacca
     2101 ggaatgtacg attttcaggg catagtagaa acattgtcaa aaaccggtaa attagttttt
     2161 aaagatcctg aaggaaatga gcttttaaca ggaaatgaca tatcaaaggc tacaactcaa
     2221 ttcgatgagt acaataagcc ggttatcggt cttgagatga atgaagaagg aagaaagaaa
     2281 tttgctgatg caaccacaaa attcgtaggt aagaaaatat caatttatat ggacgatgag
     2341 ttgctcactg atccaactgt aaatgaaccg attactcaag gtcaggcggt aattacaggt
     2401 aacagaagca tagaagatgc acgtagaata gcaggaataa taaatgcagg tgctcttcct
     2461 ttagaagtta gcactgctac agttagaaca gtaggtcctc agctaggggc taatgcattt
     2521 cctaatgcag ttaaagcagg acttataggt atagcactca tatttgtctt tatgattata
     2581 tattatagaa taccaggaat tttagcttct ttggctttaa ccttatatgt tattttagtt
     2641 ttactagcct ttgcttatat aggtgttaca atgacactgc ctggtatagc tggactactc
     2701 ctcaccatcg gtatggcggt agacgctaac gtactaatat tcgaaagaat aaaagaagaa
     2761 ctttcaacag gtaaatccgt tagatcctct gtagatgcag gcttcaacag agctttatcc
     2821 tcaataatgg attctaatat taccactata attgccggag tagtacttta cttccttggt
     2881 tcaggagcag ttaaaggttt tgctttaact ttaattattg gtattgtctt aagtatgttt
     2941 actgcaattg tagttactaa gttcctggtt catactgcat taaatatggg aataatcaac
     3001 aagcctgaac tatttggtgt taaaaggggg taaaaagcat gctaaagata atagaaaaaa
     3061 ctaaactatg gtttagtttg tcattgatag ttatggttat tggaatagga tttttggcag
     3121 ttaaaggcct taactttggt atcgatttta aaggtggaac acagctcgtt atagatatgg
     3181 ggaaggattt tgacaaacct gaggcagatg agataattaa aaagtatgat aatggagctt
     3241 taactaataa ggttgaaaac tccaaaatag agatcaagag taataattta actgaagaaa
     3301 acttaaagaa gatgcttgaa gagttaaatc aaaaatatag tttaaatgaa aaatctgtag
     3361 tttcccaaga tgtaattgga agctcaatag gtaaagagct tacaaataaa gcttatattg
     3421 cactagctat agcagtagtt ctaatgctag cttatgtagg atttagattt gagtttaaat
     3481 ttggggtagc tgccatactt gctttagttc acgatgtaat tatcaccatt agtatatatg
     3541 caattttcca aataccaata aactcgcctt ttatagcggc gattctgact attattggat
     3601 attcaatcaa tgataccata gtaatatttg acagaataag agaaaatcaa aaaattatga
     3661 gaagaaaatc tgtagaagaa gttgcaaaca taagtataac acaaactatg agacgttcca
     3721 taaataccgt tttaacaacg cttataacaa ttgtatcagt ttatatattt gttcctacag
     3781 taagggattt ttcattcccg cttataatag gaatagcaag tggtgcttat tcatcaattt
     3841 tcatagcaag tcctatatgg gttttactta aaaataaaag aaaaaagcca atataaaagc
     3901 tgcttagtat ttgttcaata taaaccttca agtaattttg aaggtttata ttgcttttga
     3961 cgaattttat ttgtcaaaga gggtattttc cattataata tagttgtttt ctattgtttt
     4021 ggaggagtta agaatgcata aattttggca gaacatttat agagctaatt atatttctgg
     4081 atataatcca tttctgttga aaaacatgaa taaggcactg gaaagagtag tgaaggctat
     4141 aaatgagagg gaaaaaataa ttatctatgg ttcctgcgat gtggatggaa tatgcgggag
     4201 ttcgctgctt cttctggttt taaagtactt aaatgcagat gtggaatact atttgcctga
     4261 agagcagagc tctaactatt atatagacga ttatatagta aaaaaccgcc taaagattct
     4321 aggcacgaat ttaattataa catcaggatg ctgcttgaaa aataaagagc aggaagatct
     4381 atgcagagaa ttaaatatag atataatagt aacagattat aagagtaatg agtttaaaag
     4441 tgattttata acgataaacc ctaatgagaa aggctgctct tacagatata aaaatctctc
     4501 tgccagtgga attgctttca agcttactca ggcattagcg atatactata atatgaaatg
     4561 cataaataag tatatagact tggttctgtt gggaagctgt gctgcggagg tatccattac
     4621 aggggaaaac aaggttatat ttaatgaagg gcttaaacat cttagacaaa ccaataacta
     4681 cggattaaag gctttaatgt ctttaaataa taaaaccagt tataatgaaa tggaaattag
     4741 agagttaata aaaatattaa cacctaaatt gaatgtggta ggaagaatgg ataacgcacg
     4801 tattgtagtt gaacttttaa ccaccagcga taaggatagg gcggagcaga tagcaaagta
     4861 tctcactatg gaacttaaaa atatagtttc ttagaaatac atattattaa atggaggatt
     4921 taatatggat tataaaagta aaataagaat aattgaagga ttcccaaaag aaggtataag
     4981 ctttaaagac attactacat taatagaaga tggggaaagc ttaagaaaat cagtagaata
     5041 gagattgcgg attatctgaa agacaagaac attgatgtta tagtaggccc tgaagcaaga
     5101 ggattcatct ttggtgttcc tgttgcatat gcactgggag ttggttttat tcctgtaaga
     5161 aaaaaggaaa ctcccatatg atactgttaa ggtggaatat gatttagaat acggcaagga
     5221 tactttagag atacataagg atgctataaa gcctggccaa agagttgcaa tagttgatga
     5281 cctccttgca actggaggaa ctatcggagc ggtagctaag cttgtagagc aggtaggagg
     5341 ggtagtggtt tctatgggat ttgctataga actaactgac ctaaaaggaa gagataagct
     5401 aggaaaatac gatataatgt cattagttca gtatgatatt taattttatt tgataaattt
     5461 aatgtaatat tatataataa aaataaattt ggctggttct gaaaccagcc attgatttta
     5521 gcctaatact ttaatacatc agatttcttt tagaggagag taattctatg atccaaaaac
     5581 tcatggaaat aattgataat aacgactatg aagtagataa aaatttaata gtaaaagcat
     5641 ttaatcttgc agaagatgct cataagactc agaaaagaga atcaggtgag ccttatatta
     5701 tgcacccttt agaggtctca tgcatattgg ctgagatggg aatggattct aatacaatag
     5761 cagcggggct tctccatgat gttattgagg atactaatta ctcctatgaa gaaattaaga
     5821 aggaattcaa cgaagaagtt gctaatttag tggatggagt cactaaatta ggtaagatta
     5881 aatataagac aaaggaagag cagcaggcag ataacgttcg aaaaatgctc cttgccatgg
     5941 ctaaggatat aagagtaata attattaaat tggcagacag acttcataat atgcggactt
     6001 taaaatttat gcctccggaa aagcagaagg aaaaatctaa agaaacactg gatatatatg
     6061 ctcctttggc tcatagactg ggaatgtcaa agattaaatg ggagctggag gatatttctt
     6121 ttagatattt gaacagcaag gaatattatg aattagtttc cttgattgca gaaaagaggg
     6181 ttgaaagaga agcgtatata tcagctatta tagaggatat gcataaaaaa ctctccggat
     6241 cgggcattga agctgacatt gaaggaagac caaaacattt ctacagtata tatagaaaaa
     6301 tggtaaataa aaacaaaagc atagagcaga tatttgactt aacagcaatt agattacttg
     6361 ttgaatctgt caaagactgc tatgcagctt taggtattgt acatactata tataagcctc
     6421 ttccaggaag gtttaaggat tatatagcaa tgcctaagcc taatatgtat caatctcttc
     6481 ataccacagt cattggaccg cagggaaaga ctttcgagat tcaaatacgc acctttgaga
     6541 tgcataagac agcagaatat ggaatagcag ctcattggaa gtataaagaa acttctccag
     6601 aggggtctgg cagcaatttt gaaaataaac ttacctggct ccgtgatata ttagaatggc
     6661 aaaaagatac atcggatgct gtggagttta tggaagcatt taaaatagat ttattttctg
     6721 atgaaatatt tgtgtttact cctaaaggag tagttattaa tttacctaat gaagctactc
     6781 ctatagattt tgcatacaaa atacacacag atataggaaa cagatgtgta ggcgcaaaag
     6841 taaatggcaa aatggtaacc ttggatcaca agcttaaaac aggagatata gttgaaatat
     6901 tgacatctgc agtggctaaa ggtcctaatt tagattggct taatatggtt aagagcaatc
     6961 aggcaaaaag caaaataagg gcctggtata aaaaggcaaa aagagatgaa aatattgtaa
     7021 aaggcaaaga gatgctggaa agggaatcca aaaagcaagg ggtaaacttt agcgaggttg
     7081 ctaagggtga tatttatgaa aaacttctaa aaagatataa ttttcataat atagaagacg
     7141 tttatgcttc agtaggtaca ggaagcttaa ttgcttctgt ggtagtatct aaacttaaag
     7201 aaggtataat cactgataag cctcagaaca gtgatgaggt taataaatct atagaagatc
     7261 aagttaataa aactaaccat aataaaacta ccaatgttgg agttactgtt aaaggtatgg
     7321 ataatattat ggttaggtat gcaaaatgct gcagtccagt agctggagat gatattattg
     7381 gctatataac taagggaaga ggaatatcaa tacatagaaa agactgtgta aacataaaaa
     7441 gtcttcccat agaggaaaaa tataagcttg ttgaagtcag ctggggaaat tctaagggag
     7501 aagaatatat ctctcaaata cagattaaag gtgaagatag aattggactt ttatctgata
     7561 ttatggcaat aatttcagaa tcaaactttc atcttcaggc tttaaatgct aaatcagtaa
     7621 aaaataatat tgctttagta acaattaaat taagtattaa ttcaatagaa cagcttcggg
     7681 atataatgaa aaagatcaga agattaaatg gagtaatgga agtatataga atgcataatt
     7741 aatatggagg atgagttatc catgagagcg gttatacaga gagtgaagga atcaaaagta
     7801 ctggtaggtg gagaagttaa aggcagtatt ggccaaggac ttaacgtact tttaggtgtt
     7861 gctaaaggag atagcgaaga agatattaaa tatttaaagg ataaaattat aaatctaaga
     7921 atttttgaag ataatgaggg gaagatgaat ttatctttaa aggatgtaaa gggtgaactc
     7981 ctaattatat ctcaatttac tttgtatgga gactgcagaa aaggcagaag accaaacttt
     8041 atgaatgccc ttgggggaga agaagcaaaa aagttatatg aaatttttat agagtcctgt
     8101 aaatcagagg ggataaaagt ggaaacagga gttttcgggg cagaaatgga tgtttttatc
     8161 ttaaatgacg gacctgttac agtaatatta gaaagtgata aaagctttta aatgaggtga
     8221 aataatgttt attaaaagga tgccagcggg aatatatgca gctaactgtt atattattac
     8281 tgatgaaaat acaaaggacg cattagttat agatcccggc ggagatgaag atgatattat
     8341 agattatata aatgaaaaag ggttaaaggt tcaagctgtt cttgtaactc acggacattt
     8401 tgatcatgtg ggtgcagtga gagttttagc agaaaaatac gatgttaaaa tatatattaa
     8461 tgaaaaggat caccgtctta tggaaaaagg tgctggtgct tttggagata taagcggttc
     8521 agatattatt tacataggtg ataatgaggt cataaagttt ggttccatag agattaaggc
     8581 tatagagact ccaggtcaca gtccaggaag tatgagttat ctagttaaag atgacctgtt
     8641 taccggtgat gcacttttcc agatgtctat tggaagaact gacttagaag gaggagattt
     8701 cgatactctc ataagcagca tagtagaaaa gctaataata ttaggtgacc atataaatgt
     8761 tcatccggga catggtatga gctctaccat acagcaggaa agactttata atccttatct
     8821 aaattaaagg gagaggctat gaaaatagac atattactta ataatctaaa ttatagatat
     8881 gatatttatc agatatttaa tatattttat tctttagaag aaatatcctt taatcatgat
     8941 aaagaagatt atgaagatta taaggtcata attgaaagcg accgtgtcta tatatcccat
     9001 aaccatatga aaaaaagcta cgaagactcg gaaaatatag ggtgcaaaaa ttttattaaa
     9061 aaagctgttt ttcaattcct tacagaagaa acaaaagagc attttccatg gggaacttta
     9121 gttggtatta gacctagtaa aatagcttta gaccttatta ataaaggctt aacagctgag
     9181 gaaataatat catattttaa tagggtttac tgtactgaca gggataaagc tcaattatgt
     9241 atagacattg caaaatatga aaactctttt gtaaacaaca aagagaataa cataagtata
     9301 tatttaggta tgccattttg tcctacaagg tgtgcatact gttcttttgc atcaaatcca
     9361 atttctgcct gtaaacctct tgtagagccc tatttactgg ctcttaaaaa ggaaattgaa
     9421 ttcataagag attatatcaa tgaaagaaag ctcactgtag aaaccgtgta ttttggagga
     9481 ggaactccta cctcagttga tgatgaacaa tttaagttta ttatgaaagc tatttttgat
     9541 aatttaattt taaataaaaa tgttaaagaa ttcacagtgg aatgcggaag acctgatagt
     9601 ttgtctaata gtaaattgga aacactaaag aaatataatg ttaccaggat aagcataaat
     9661 cctcagacta tgaatgactc aacccttaaa gggataggaa gaaaacacag ttcaaaggat
     9721 ataatagata tattcaataa agcaagagag cttggatttg ataatatcaa tatggattta
     9781 atcgttggtc ttccaggtga aggattggat catgtaaggc atacctgcag tgaaatatta
     9841 aagcttagtc ctgaaagcgt tacagtacat ggaatgtcaa taaagagagc ttctgatctt
     9901 catgaaaaaa tccttttaaa gcaatattat tataaaccta atcaaaagga attaaatagc
     9961 atgtataatg aaacgagggc tttggctgaa aagcttaata tgatacccta ttatatgtat
    10021 agacaaaaaa atatggttgg taatatggaa aatgtgggat atactataat aggcagagaa
    10081 tgtgtataca atattgaaat gatagaagaa aagcagacca ttattgcttt aggagcggac
    10141 gctgtcacta aggtagtttt tcaaaaagat aacagaatag aaagatttgg aaatttgaaa
    10201 gaagtaaaac aatatataga taaaattgat gctatgattg aaggtaaaat aaagctatta
    10261 gatagccttt ataaagataa caattaagaa ttttaaatac tgtcaggagg aatatatatg
    10321 ggtgaggcgt taaagggact taagcgcaat acaatgtgtg gagaactcag ggaagaacat
    10381 attgggacca aatttaccgt aatgggatgg gttcagagaa aaagaaatct cggaggcttg
    10441 gtttttatag atttaaggga taggacagga atacttcagg tggttttcgg agaaaagata
    10501 aatacagaag cttttcataa atctgattct gtgaagcctg aatactgtat agcagtgact
    10561 ggtgaactag ttaaaagaga gtccgttaat gcaggtatgc ctacaggaat ggtggaatta
    10621 aaaggagaat ctataaagat tttatctgaa tcagaaacac ctcctattta tataaaggaa
    10681 ggcctggatg cagctgaaaa tataagatta aaatatagat acttagattt aagaaggcct
    10741 gatatgcaga ggatattttt cataaggcat aaagctgcta aggcaattcg tgactttttg
    10801 gatgataatg gatttttaga agtagaaact cctatgttaa ctaaaagcac acctgagggt
    10861 gccagagatt atttagtacc aagcagaaat tatccaggaa tgttctatgc ccttcctcaa
    10921 tctccacagc tttttaaaca gcttttgatg gtttcagggt ttgatagata tttccagata
    10981 gtaaagtgtt ttagagatga agatttaaga gcaaacaggc agccggagtt tactcaggtg
    11041 gatatagagc tttccttcgt agaagaagat gatgttatgg agttaaatga gaagctaatt
    11101 gctcacgtat ttaaaaaggt gctaaataaa gaaataccta caccatttag aagaatgcct
    11161 tacagagagg ctatggagaa gtatggaagc gataagcctg atttaagatt tggtatggaa
    11221 attaaagatt taaccgatgc agtaaaaaat agcgagttca aagtttttgc agaggcagtg
    11281 aagagcggtg gatcagttag agcattaact gttaaatccg ggtcaaccat gggaagaaaa
    11341 gatattgaca ggttaggtga gtttgtaaaa acatataagg caaaaggttt agcgtggata
    11401 gcttataaag aagatgaaat aaaatcccct attgctaagt tccttactga agaggaaatg
    11461 aagaatataa tagaaaaagc tgaagctgaa actggcgact taatacttat tgtagcggac
    11521 aaaaacagtg tagttttgca atctttagga gcattacgtc tggaaattgc aaagaaactt
    11581 gaactattaa aggataataa tgaatttaac tttgtttgga taacagaatt tcctctttta
    11641 gaatacgacg aagaagaagg taggtatttt gctgctcacc atcccttcac cgctccaatg
    11701 gaggaagata tta
//
