LOCUS       c00034_NZ_CABK..       22478 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CABKTP010000034.1 Clostridium polynesiense isolate
            MGYG-HGUT-01479, whole genome shotgun sequence.
ACCESSION   c00034_NZ_CABK..
VERSION     c00034_NZ_CABK..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 16:34:29
            Original ID  :: NZ_CABKTP010000034.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 22478
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22478
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[9030:12478]"
                     /cutoff="20000"
                     /detection_rule="((((goadsporin_like or PF00881 or
                     TIGR03605) and (YcaO or TIGR03882 or TIGR03604)) or
                     TIGR03603 or TIGR03602) and not cyanobactin_synth)"
                     /neighbourhood="10000"
                     /product="LAP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      9031..12478
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((((goadsporin_like or PF00881 or
                     TIGR03605) and (YcaO or TIGR03882 or TIGR03604)) or
                     TIGR03603 or TIGR03602) and not cyanobactin_synth)"
                     /neighbourhood="10000"
                     /product="LAP"
                     /protocluster_number="1"
     protocluster    1..22478
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[7869:12478]"
                     /cutoff="20000"
                     /detection_rule="((YcaO or TIGR03882) and ((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or PF07366 or PF06968 or PF04055) or
                     thiostrepton)"
                     /neighbourhood="10000"
                     /product="thiopeptide"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      7870..12478
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((YcaO or TIGR03882) and ((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or PF07366 or PF06968 or PF04055) or
                     thiostrepton)"
                     /neighbourhood="10000"
                     /product="thiopeptide"
                     /protocluster_number="2"
     cand_cluster    1..22478
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((YcaO or TIGR03882) and ((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or PF07366 or PF06968 or PF04055) or
                     thiostrepton)"
                     /detection_rules="((((goadsporin_like or PF00881 or
                     TIGR03605) and (YcaO or TIGR03882 or TIGR03604)) or
                     TIGR03603 or TIGR03602) and not cyanobactin_synth)"
                     /kind="chemical_hybrid"
                     /product="thiopeptide"
                     /product="LAP"
                     /protoclusters="2"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..22478
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="thiopeptide"
                     /product="LAP"
                     /region_number="1"
                     /rules="((YcaO or TIGR03882) and ((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or PF07366 or PF06968 or PF04055) or thiostrepton)"
                     /rules="((((goadsporin_like or PF00881 or TIGR03605) and
                     (YcaO or TIGR03882 or TIGR03604)) or TIGR03603 or
                     TIGR03602) and not cyanobactin_synth)"
                     /tool="antismash"
     CDS             2..625
                     /locus_tag="ctg34_1"
                     /transl_table=11
                     /translation="ATLFALLGVIVYGGVKLNWDLEETAAVFMWMGILAGIFAGFGPSK
                     IAKYMVDGAKKMIGAALIIGLARSVSGILTAGKIMDTCIYGMAQVLGLLPAYVQGMAMY
                     IANLIMNVFITSGSGLANTVMPLFVPLADLVGLTRQSAVLAFNFGDGFGNYVLPTSSAL
                     MGILGAANIPYDRWMKFMWKLFLIWVAVGSALMVVAQIIKFGPM"
     PFAM_domain     8..601
                     /aSDomain="DcuC"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03606.17"
                     /description="C4-dicarboxylate anaerobic carrier"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg34_1_0001"
                     /evalue="2.90E-44"
                     /label="ctg34_1"
                     /locus_tag="ctg34_1"
                     /protein_end="200"
                     /protein_start="2"
                     /score="151.4"
                     /tool="antismash"
                     /translation="LFALLGVIVYGGVKLNWDLEETAAVFMWMGILAGIFAGFGPSKIA
                     KYMVDGAKKMIGAALIIGLARSVSGILTAGKIMDTCIYGMAQVLGLLPAYVQGMAMYIA
                     NLIMNVFITSGSGLANTVMPLFVPLADLVGLTRQSAVLAFNFGDGFGNYVLPTSSALMG
                     ILGAANIPYDRWMKFMWKLFLIWVAVGSALMVVAQ"
     CDS             638..1813
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1244:amidohydrolase (Score: 244.8; E-value: 2.1e-74)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg34_2"
                     /transl_table=11
                     /translation="LKQSLYKNINDRSNKLIAMADYIFDNPEIAFKEYKASKLISDYLK
                     EQGFKVELGLGSLDTAFKAVYENGQGGPNIGLLCEYDALPMGHGCAHHMQGPSIIGAAA
                     AIKALYNKKPYKLTVYGTPAEEGGGGKIKMINEGYIKELDVALMMHGGPATQVDVKSLA
                     ASSIKVIYHGRSAHAALKPEQGRSALDALLLTFQAVEFLREHVQEDTKMHYTVIDAGGP
                     NNVVPKTASGSFSLRSYNSSYLKSVIERFEDIVKGAALMTGTTYEIIREKDLDSKVPVY
                     SLNDLVMNNAELINAPNIKPARQKTGSSDFGNVMYIIPGSCIRTSFVDENASSHSQEFL
                     DDGKTQRGHEAIINAAKILAGTVFDLIDNPSLLREVKQEFNDTKAKMSVDN"
     aSDomain        683..1651
                     /aSDomain="TIGR01891"
                     /aSTool="tigrfam"
                     /description="amidohydrolases: amidohydrolase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg34_2_0001"
                     /evalue="4.40E-62"
                     /identifier="TIGR01891"
                     /label="ctg34_2"
                     /locus_tag="ctg34_2"
                     /protein_end="338"
                     /protein_start="15"
                     /score="208.3"
                     /tool="antismash"
                     /translation="LIAMADYIFDNPEIAFKEYKASKLISDYLKEQGFKVELGLGSLDT
                     AFKAVYENGQGGPNIGLLCEYDALPMGHGCAHHMQGPSIIGAAAAIKALYNKKPYKLTV
                     YGTPAEEGGGGKIKMINEGYIKELDVALMMHGGPATQVDVKSLAASSIKVIYHGRSAHA
                     ALKPEQGRSALDALLLTFQAVEFLREHVQEDTKMHYTVIDAGGPNNVVPKTASGSFSLR
                     SYNSSYLKSVIERFEDIVKGAALMTGTTYEIIREKDLDSKVPVYSLNDLVMNNAELINA
                     PNIKPARQKTGSSDFGNVMYIIPGSCIRTSFVDENASSHSQE"
     PFAM_domain     1133..1408
                     /aSDomain="M20_dimer"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07687.16"
                     /description="Peptidase dimerisation domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg34_2_0002"
                     /evalue="7.60E-09"
                     /label="ctg34_2"
                     /locus_tag="ctg34_2"
                     /protein_end="257"
                     /protein_start="165"
                     /score="35.6"
                     /tool="antismash"
                     /translation="SIKVIYHGRSAHAALKPEQGRSALDALLLTFQAVEFLREHVQEDT
                     KMHYTVIDAGGPNNVVPKTASGSFSLRSYNSSYLKSVIERFEDIVKG"
     CDS             complement(1883..2446)
                     /locus_tag="ctg34_3"
                     /transl_table=11
                     /translation="MYTPYQMYPYYMNIPQYNLDIMYNYYSTPPHFPNMPRSNSELWRI
                     ELKDYGPQPFVVNIEDATLQNNNFRTALWTGNHLQLTLMSIPVGGDTGLEIHPNLDQFV
                     RLEQGEGIIRMGDRRDYLIFQERVYEDFAFIIPAGKWHNLINTGHEPIKLYSIYSPPQH
                     PKGTVHVTMAEAEAAEQQFQTQTT"
     PFAM_domain     complement(1973..2200)
                     /aSDomain="Cupin_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07883.13"
                     /description="Cupin domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg34_3_0003"
                     /evalue="2.30E-13"
                     /label="ctg34_3"
                     /locus_tag="ctg34_3"
                     /protein_end="158"
                     /protein_start="82"
                     /score="49.7"
                     /tool="antismash"
                     /translation="LMSIPVGGDTGLEIHPNLDQFVRLEQGEGIIRMGDRRDYLIFQER
                     VYEDFAFIIPAGKWHNLINTGHEPIKLYSIY"
     CDS             2643..3425
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 208.5; E-value:
                     1.9e-63)"
                     /gene_kind="transport"
                     /locus_tag="ctg34_4"
                     /transl_table=11
                     /translation="MNISDKLLQVQGVYKTYGEGQSETAALKGITFDVLPGEFLGIMGA
                     SGSGKTTLLNCIATMLKPTSGQILLENQNISSFKGSQLAKYRGSKIGYLFQEFELLDNL
                     TARENILLPLLIHGENSKNQELQLQRLVEQFDIGEVLNKFPSQMSGGQKQRVAAARALI
                     SNPSIVLADEPTGALDTKNAKSLMEKLSSINKNEGSAILMVTHDANAASFCSRILFIQD
                     GVIFHELRKKVPVENRDSFYERILTVMAQLGGGSSNVL"
     PFAM_domain     2721..3167
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg34_4_0004"
                     /evalue="5.40E-35"
                     /label="ctg34_4"
                     /locus_tag="ctg34_4"
                     /protein_end="175"
                     /protein_start="26"
                     /score="121.0"
                     /tool="antismash"
                     /translation="LKGITFDVLPGEFLGIMGASGSGKTTLLNCIATMLKPTSGQILLE
                     NQNISSFKGSQLAKYRGSKIGYLFQEFELLDNLTARENILLPLLIHGENSKNQELQLQR
                     LVEQFDIGEVLNKFPSQMSGGQKQRVAAARALISNPSIVLADEPT"
     CDS             3415..5265
                     /gene_functions="transport (smcogs) SMCOG1243:ABC
                     transporter, permease component (Score: 120.5; E-value:
                     1.4e-36)"
                     /gene_kind="transport"
                     /locus_tag="ctg34_5"
                     /transl_table=11
                     /translation="MFFNFIKRNSRKVRKENGVYFASLIISIVAFYVILSLGDQDVMVY
                     LKTVESDAVEKLMLMIPMLYGLSLFFVYFLVYFANRYQLQRRNHEFGIYLMMGMKRSKL
                     FAMIVGETLWNGLVALFIGIPISIFLTELISMATSRLIGMGIIGHEFRISWIGIGLTVL
                     GFIMVQLGAVFILSLKMSRKEPVELLNEGKEKVQKLISPKWGVISFLLGAVLLCTAYIL
                     ALLYLKNLDFKMFGLILIIGISGTFMLFRGLGSLIGAWIKSKSRYSQGLFIFTGRQLQE
                     NVLHQWNSLAISSLLILMAMVCFAYGISTTLNRGAASARTVDFTFKGSEEEITAVLTSD
                     KLKPYVEDYYVMKIGHFRTKYREKPEKSTQHTFSWAGLKESISREEDSEEKDFLLRDLS
                     YRDSPYLISLSSYNALLNSMNKSPIILRENEAAMYSYAEFSKSHDILRKVLQSNPTVKI
                     GEKQYKLASELYTSNIVADRAITLSYALIVPDEVYNSFAYISKDSVLWNMTIDSEFIKE
                     KGLMQAMNEVDKLLKNSGLHYESYLSSMGRQIFYMVAGSYTTLYLSLMFLIIANTVLGL
                     KFLMQQRSTRSRYPTVSVLGGHGLKISVHQQEYKSGGISV"
     PFAM_domain     3682..3969
                     /aSDomain="FtsX"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02687.23"
                     /description="FtsX-like permease family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg34_5_0005"
                     /evalue="5.30E-09"
                     /label="ctg34_5"
                     /locus_tag="ctg34_5"
                     /protein_end="185"
                     /protein_start="89"
                     /score="36.5"
                     /tool="antismash"
                     /translation="EFGIYLMMGMKRSKLFAMIVGETLWNGLVALFIGIPISIFLTELI
                     SMATSRLIGMGIIGHEFRISWIGIGLTVLGFIMVQLGAVFILSLKMSRKEP"
     CDS             5280..5480
                     /locus_tag="ctg34_6"
                     /transl_table=11
                     /translation="LVSSIFGIPSMMGAFLIVPKGLDVKISTITFAVGLALSAFIVFEL
                     CYIWMIQRKSDEEINKLKEIK"
     CDS             5492..6169
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 130.2; E-value: 1.4e-39)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg34_7"
                     /transl_table=11
                     /translation="VEKIVIVEDDVFLREEIQNILEKEGYFVECISSFDSIFEDIDTIS
                     PSLIILDLNLPNLSGFDMCRGLKVRGIGPILVLTSRNQLKDELHALDLGADDYLTKPCH
                     PKRLIARIQKLIHLYSNLNVVLDAGDFQLDENANILYAGKNFVLLTDNEGIIMKALVKA
                     APSVVKKEEFFRLLWGSSDYVDENILQVNMTRLRKTLEKAGLFNRIRTVRGVGYQLTGG
                     DSK"
     PFAM_domain     5501..5830
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg34_7_0006"
                     /evalue="6.00E-24"
                     /label="ctg34_7"
                     /locus_tag="ctg34_7"
                     /protein_end="113"
                     /protein_start="3"
                     /score="84.5"
                     /tool="antismash"
                     /translation="IVIVEDDVFLREEIQNILEKEGYFVECISSFDSIFEDIDTISPSL
                     IILDLNLPNLSGFDMCRGLKVRGIGPILVLTSRNQLKDELHALDLGADDYLTKPCHPKR
                     LIARIQ"
     PFAM_domain     5930..6148
                     /aSDomain="Trans_reg_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00486.30"
                     /description="Transcriptional regulatory protein, C
                     terminal"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg34_7_0007"
                     /evalue="6.20E-17"
                     /label="ctg34_7"
                     /locus_tag="ctg34_7"
                     /protein_end="219"
                     /protein_start="146"
                     /score="61.6"
                     /tool="antismash"
                     /translation="VLLTDNEGIIMKALVKAAPSVVKKEEFFRLLWGSSDYVDENILQV
                     NMTRLRKTLEKAGLFNRIRTVRGVGYQL"
     CDS             6166..7197
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 99.4; E-value: 4.5e-30)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg34_8"
                     /transl_table=11
                     /translation="MKLKDWLNIIRETHPWILIICISDAFFIFLAWLAYPENFKILVAT
                     MIIFSVLSIATGILLVRKRQEKKDKAFYDFLREPSMEHEGDLIDSIGELHKEKVNYLAD
                     KVRTMKDKLDETKLQNIDYEEFIESWVHEIKTPISLATLVLENRKEEMSPLVYQRLEHA
                     RINILDDVERILFYARLKASHVDYNLERISLELCCEDVLLELQALLDEKEVKIISNMTD
                     VPIVSDKKALQFIITQILLNSVKYSKKEIESFIRLNSGFDSIKKRYYLRIFDNGIGVLS
                     SDLPFIFDKGFTGDNRSHNQSSGIGLYLVKKLCDELKIEIEVDSEYGKGFTFQLLFPLI
                     EDI"
     PFAM_domain     6847..7182
                     /aSDomain="HATPase_c"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02518.28"
                     /description="Histidine kinase-, DNA gyrase B-, and
                     HSP90-like ATPase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg34_8_0008"
                     /evalue="9.90E-16"
                     /label="ctg34_8"
                     /locus_tag="ctg34_8"
                     /protein_end="339"
                     /protein_start="227"
                     /score="58.3"
                     /tool="antismash"
                     /translation="DKKALQFIITQILLNSVKYSKKEIESFIRLNSGFDSIKKRYYLRI
                     FDNGIGVLSSDLPFIFDKGFTGDNRSHNQSSGIGLYLVKKLCDELKIEIEVDSEYGKGF
                     TFQLLFPL"
     CDS             7870..8988
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thiopeptide: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg34_9"
                     /sec_met_domain="PF04055 (E-value: 3.3e-17, bitscore: 54.5,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 2.7e-12, bitscore:
                     38.1, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKCSFCGAWNQDNAGEFIDLEKVKEIILHASKKGYRYISFSGGEP
                     LQYKYIYDVIEYANNLGFFINLTTNGLLIDDSFVKNIGNKNVNTRISFHSLNKDLFNGI
                     TGRESSDKVRESIQRLKKEKIVFSIGATIFEDNINEVQALAQFALEEGAEYIRFTPVYR
                     VYKGRNFNIDSIFFERLLFHIVKFALGNKKSLQYKKRTALYLSNFINIITTKQCAAGSD
                     YYIAVNPDLNIVSCPVLPHYSGSYTEKYSSFENIESLKGYYKNLLTKELVSNLKGQCRD
                     CKYKHTCKGGCISTKLEEQLSLEEEQPICLMKIVNNVLDKLSPREMEDIISYWKYQYDK
                     KVMFNDDSSGCIRRLPIWELHFNNKYSYDYKK"
     PFAM_domain     7873..8310
                     /aSDomain="Radical_SAM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04055.23"
                     /description="Radical SAM superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg34_9_0009"
                     /evalue="1.50E-14"
                     /label="ctg34_9"
                     /locus_tag="ctg34_9"
                     /protein_end="147"
                     /protein_start="1"
                     /score="54.8"
                     /tool="antismash"
                     /translation="KCSFCGAWNQDNAGEFIDLEKVKEIILHASKKGYRYISFSGGEPL
                     QYKYIYDVIEYANNLGFFINLTTNGLLIDDSFVKNIGNKNVNTRISFHSLNKDLFNGIT
                     GRESSDKVRESIQRLKKEKIVFSIGATIFEDNINEVQALAQF"
     aSDomain        8518..8799
                     /aSDomain="TIGR04085"
                     /aSTool="tigrfam"
                     /description="rSAM_more_4Fe4S: radical SAM additional
                     4Fe4S-binding SPASM domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg34_9_0002"
                     /evalue="3.60E-10"
                     /identifier="TIGR04085"
                     /label="ctg34_9"
                     /locus_tag="ctg34_9"
                     /protein_end="310"
                     /protein_start="216"
                     /score="38.1"
                     /tool="antismash"
                     /translation="CAAGSDYYIAVNPDLNIVSCPVLPHYSGSYTEKYSSFENIESLKG
                     YYKNLLTKELVSNLKGQCRDCKYKHTCKGGCISTKLEEQLSLEEEQPIC"
     CDS             9031..9852
                     /gene_functions="biosynthetic (rule-based-clusters) LAP:
                     PF00881"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg34_10"
                     /sec_met_domain="PF00881 (E-value: 3.6e-10, bitscore: 31.3,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MASNFKKKKMTLNEFMETETPGLMSIFDFASNLPISLYVDTTAVK
                     IPEICYSSSLLSQTHFLSETYLLNRKRNSLDLGLQYGVMGYSSFLVRGSIVQRKLAEEE
                     ELEKENSVIQLPKYKNLKNPLGATIRARRSIREMTDKSVSLEDLSTILFYGDGVSGDLQ
                     LTSEDEDIFPKSSLGEDYNGTLRTAPSGGGLFPVNLYLVIRKVKGIKDGIYVYMPLNHS
                     LKVIKYLEEEAAEELKTVVEWGYNIDSSKINVIVFYVYNLYDNSRKYLDMA"
     PFAM_domain     9415..9768
                     /aSDomain="Nitroreductase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00881.26"
                     /description="Nitroreductase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg34_10_0010"
                     /evalue="2.60E-06"
                     /label="ctg34_10"
                     /locus_tag="ctg34_10"
                     /protein_end="246"
                     /protein_start="128"
                     /score="27.7"
                     /tool="antismash"
                     /translation="IRARRSIREMTDKSVSLEDLSTILFYGDGVSGDLQLTSEDEDIFP
                     KSSLGEDYNGTLRTAPSGGGLFPVNLYLVIRKVKGIKDGIYVYMPLNHSLKVIKYLEEE
                     AAEELKTVVEWGYN"
     CDS             9862..10026
                     /gene_functions="biosynthetic (rule-based-clusters) LAP:
                     PF00881"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg34_11"
                     /sec_met_domain="PF00881 (E-value: 9.2e-10, bitscore: 30.0,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIEAGQISQNIHLTATALTIASCDVGGFDKFKSEQFIGVDGLSKN
                     IINVTILGN"
     PFAM_domain     9865..9996
                     /aSDomain="Nitroreductase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00881.26"
                     /description="Nitroreductase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg34_11_0011"
                     /evalue="4.70E-05"
                     /label="ctg34_11"
                     /locus_tag="ctg34_11"
                     /protein_end="45"
                     /protein_start="1"
                     /score="23.6"
                     /tool="antismash"
                     /translation="IEAGQISQNIHLTATALTIASCDVGGFDKFKSEQFIGVDGLSKN"
     CDS             10038..11129
                     /gene_functions="biosynthetic (rule-based-clusters) LAP:
                     TIGR03603"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Cytolysin_C_RRE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg34_12"
                     /sec_met_domain="TIGR03603 (E-value: 1.5e-52, bitscore:
                     170.3, seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="Cytolysin_C_RRE (E-value: 8.7e-17,
                     bitscore: 52.5, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGITKYILAENVVVFNNGVDEIRVRRGIWNYEEAIISVEGLTDTM
                     KEIINEMVRTLDIGEELDAEKVLSDKRLLQHEKDSIEGLVLGLKEQGYIRDSEESKTTQ
                     LLYEILNGSIQARFLQNDIYLKPILFFSDSEDVKNYAVALCNKMSLPIHVVSEEEYREI
                     IKMDLTSRFDGYETSKAVKKLVKFIEPYSCLVGGLQKVNVSFMRNLNRALIEANKPLSM
                     ALIDGPFTTVFTIKPPETGCFECMEQRLTARIEDMQVYRRFVEHTRGMNVSAVNSYAAP
                     IMNSIVSTAIFEGLIISAVGKSKLAGRALNTYIPVMEIQVEDILRVPFCPACGTIAKAK
                     IEEMYTSTRKMVDKIIDNIELGN"
     CDS             11141..12478
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thiopeptide: YcaO"
                     /gene_functions="biosynthetic (rule-based-clusters) LAP:
                     YcaO"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg34_13"
                     /sec_met_domain="YcaO (E-value: 2.5e-42, bitscore: 136.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLRYYPSNIRLKNKFKSINAQHFGIMESQILTTAKGKYSPEVSVC
                     TANMPDYHKIIIDEKAEMNHHLSGYGIYFEESLIRLLGEGIERYALLTASEIYKDKEIM
                     ASYNEVSKLGEVMPWEYIDMYTKEDYDRLLSFTNIQKIDKDTKISWIKCPSILDKDREI
                     LIPAQLLFIGFRNKREREAIFAPGFSKGAASHVTLENALESAMMESVEADAFTINWYTS
                     RKTRKIIVDDESLLEIIIKTTKDIQCDVLPLEFSLEGMPGHTVGVALINKNNNRPTVVL
                     GCQSALDPKKAIYKALLESLAIHYLAVNGPLLLPNLYLASVKDNNFNNLDSNVAFWANQ
                     SDIDMKKSYFYDLCKEEVMLSSLECYEKEDKVEEIRYIKDKISKVSKYGVYLDITPPEV
                     SDKGWKVIRTFFPELVQMSLPSFPYSNHPRLKEYGGVLNALPHPVP"
     PFAM_domain     11342..12382
                     /aSDomain="YcaO"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02624.18"
                     /description="YcaO cyclodehydratase, ATP-ad Mg2+-binding"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg34_13_0012"
                     /evalue="4.60E-37"
                     /label="ctg34_13"
                     /locus_tag="ctg34_13"
                     /protein_end="414"
                     /protein_start="67"
                     /score="128.2"
                     /tool="antismash"
                     /translation="SGYGIYFEESLIRLLGEGIERYALLTASEIYKDKEIMASYNEVSK
                     LGEVMPWEYIDMYTKEDYDRLLSFTNIQKIDKDTKISWIKCPSILDKDREILIPAQLLF
                     IGFRNKREREAIFAPGFSKGAASHVTLENALESAMMESVEADAFTINWYTSRKTRKIIV
                     DDESLLEIIIKTTKDIQCDVLPLEFSLEGMPGHTVGVALINKNNNRPTVVLGCQSALDP
                     KKAIYKALLESLAIHYLAVNGPLLLPNLYLASVKDNNFNNLDSNVAFWANQSDIDMKKS
                     YFYDLCKEEVMLSSLECYEKEDKVEEIRYIKDKISKVSKYGVYLDITPPEVSDKGWKVI
                     RTFFPEL"
     aSDomain        11345..12475
                     /aSDomain="TIGR03604"
                     /aSTool="tigrfam"
                     /description="TOMM_cyclo_SagD: thiazole/oxazole-forming
                     peptide maturase, SagD family component"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg34_13_0003"
                     /evalue="1.60E-69"
                     /identifier="TIGR03604"
                     /label="ctg34_13"
                     /locus_tag="ctg34_13"
                     /protein_end="445"
                     /protein_start="68"
                     /score="232.6"
                     /tool="antismash"
                     /translation="GYGIYFEESLIRLLGEGIERYALLTASEIYKDKEIMASYNEVSKL
                     GEVMPWEYIDMYTKEDYDRLLSFTNIQKIDKDTKISWIKCPSILDKDREILIPAQLLFI
                     GFRNKREREAIFAPGFSKGAASHVTLENALESAMMESVEADAFTINWYTSRKTRKIIVD
                     DESLLEIIIKTTKDIQCDVLPLEFSLEGMPGHTVGVALINKNNNRPTVVLGCQSALDPK
                     KAIYKALLESLAIHYLAVNGPLLLPNLYLASVKDNNFNNLDSNVAFWANQSDIDMKKSY
                     FYDLCKEEVMLSSLECYEKEDKVEEIRYIKDKISKVSKYGVYLDITPPEVSDKGWKVIR
                     TFFPELVQMSLPSFPYSNHPRLKEYGGVLNALPHPVP"
     CDS             12453..13130
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg34_14"
                     /sec_met_domain="Abi (E-value: 3.6e-11, bitscore: 34.6,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPYHTQFLKLIIVLAMVMLPLGLGSNVSYLISTMIRKKTIGFNLL
                     GMVLSYGLIVILVWFAGYKEVFFFKKATLYFYLFAPFIGITCIGIEYLAGVIINFVSSG
                     KWVFKISIHSSYSRVEKIKKFDILMIVLFAVIEELLYRQVLVNLLQINFNISEISLILV
                     SSIVFAFNHINFGAFAAFQKLFSGLIFTCIYLLSGYSILVPAIAHASQNLSLLFASRAG
                     EFK"
     PFAM_domain     12831..13091
                     /aSDomain="Rce1-like"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02517.18"
                     /description="Type II CAAX prenyl endopeptidase Rce1-like"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg34_14_0013"
                     /evalue="1.70E-08"
                     /label="ctg34_14"
                     /locus_tag="ctg34_14"
                     /protein_end="213"
                     /protein_start="126"
                     /score="34.8"
                     /tool="antismash"
                     /translation="ILMIVLFAVIEELLYRQVLVNLLQINFNISEISLILVSSIVFAFN
                     HINFGAFAAFQKLFSGLIFTCIYLLSGYSILVPAIAHASQNL"
     CDS             13127..13858
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg34_15"
                     /sec_met_domain="Abi (E-value: 8e-10, bitscore: 30.3,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSQLIKFALFIFFAGVYTIVWGKTVSTLVKSKIVVKIAKFLMNY
                     SRMKLDPIRFLIIWLGYLFVSIVGTIVFSVIFKINILDYIHLKNYKEILLYSLIGFIVQ
                     LSLSSMILTVISLIKSDINWYSVISNISWVKISSKLPKWIKPLYPISGAFFEELYFRGC
                     IFIIIITEFKFIHPLLAIILISILFSVQQVLNTETVYQAVSMSVGAVCISAVGCMLILA
                     TNSFIPALLCHELYVLFYIKH"
     CDS             13875..14792
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 172.4; E-value:
                     2.1e-52)"
                     /gene_kind="transport"
                     /locus_tag="ctg34_16"
                     /transl_table=11
                     /translation="MIIEVKNLNVRYKDKKAVNNVSFNVNQGEVFGMIGANGAGKTTTI
                     ECIEGLRNNYDGEIKILGLSPKKDRKKLHKLIGVQLQETSYQDRLKVKEICRLFASFYE
                     EKEDFGALAKEFGLHDKLNSYVGKLSGGQRQKLSIILALISKPKVIFLDELTTGLDPKS
                     RKDMWETVLTLKNRGITIYLTTHFMEEAEYLCDRVAIMKEGKIAALDTVDNLKNNHGLL
                     DKVSFLCNEGINKDALMNFESVKEVADKNNYFTISCDADGFLKELNQYVMENHCIIMNT
                     EVKKPSLEDVFFKYTGDTLENVED"
     PFAM_domain     13926..14342
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg34_16_0014"
                     /evalue="1.40E-28"
                     /label="ctg34_16"
                     /locus_tag="ctg34_16"
                     /protein_end="156"
                     /protein_start="17"
                     /score="100.2"
                     /tool="antismash"
                     /translation="VNNVSFNVNQGEVFGMIGANGAGKTTTIECIEGLRNNYDGEIKIL
                     GLSPKKDRKKLHKLIGVQLQETSYQDRLKVKEICRLFASFYEEKEDFGALAKEFGLHDK
                     LNSYVGKLSGGQRQKLSIILALISKPKVIFLDELT"
     PFAM_domain     14508..14762
                     /aSDomain="DUF4162"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13732.8"
                     /description="Domain of unknown function (DUF4162)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg34_16_0015"
                     /evalue="1.50E-06"
                     /label="ctg34_16"
                     /locus_tag="ctg34_16"
                     /protein_end="296"
                     /protein_start="211"
                     /score="28.9"
                     /tool="antismash"
                     /translation="VDNLKNNHGLLDKVSFLCNEGINKDALMNFESVKEVADKNNYFTI
                     SCDADGFLKELNQYVMENHCIIMNTEVKKPSLEDVFFKYT"
     CDS             14795..15538
                     /gene_functions="transport (smcogs) SMCOG1065:ABC-2 type
                     transporter (Score: 78.7; E-value: 6.6e-24)"
                     /gene_kind="transport"
                     /locus_tag="ctg34_17"
                     /transl_table=11
                     /translation="MEAFGEMIKTEFKCFTRNFINMFFVLAFPGLFLILFGEIYGNDPS
                     PLFNGQGTIDASVPAYIGMIIAVTGIMSLPLALASYREKKILKRFKATPISPFHILVSQ
                     IIVNLIMTIIGGGLLILIGKVGYDLTFSGKVLPLILVILLSIICIFSIGFLIASVVNGT
                     KAANAVANLVYFPMLFLTGATLPLETMPDKIKKVSELLPLTHCIKMMKGLWQGSSITDF
                     GSEIMIVAGVTIVCSLLSIKFFRWD"
     PFAM_domain     14801..15424
                     /aSDomain="ABC2_membrane"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01061.26"
                     /description="ABC-2 type transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg34_17_0016"
                     /evalue="7.80E-31"
                     /label="ctg34_17"
                     /locus_tag="ctg34_17"
                     /protein_end="210"
                     /protein_start="2"
                     /score="107.2"
                     /tool="antismash"
                     /translation="AFGEMIKTEFKCFTRNFINMFFVLAFPGLFLILFGEIYGNDPSPL
                     FNGQGTIDASVPAYIGMIIAVTGIMSLPLALASYREKKILKRFKATPISPFHILVSQII
                     VNLIMTIIGGGLLILIGKVGYDLTFSGKVLPLILVILLSIICIFSIGFLIASVVNGTKA
                     ANAVANLVYFPMLFLTGATLPLETMPDKIKKVSELLPLTHCIKMM"
     CDS             15628..15993
                     /locus_tag="ctg34_18"
                     /transl_table=11
                     /translation="LRRSDVFYMKIIVFLTFVFAVVVILISLLYGFSVFLKNKKALLES
                     EDATVISKKNVNNTSFISNYFLNNTSFLVVFKMDSKADKKFMVSKKIYDSLEINEKGIL
                     NYKGTKFIEFIKSGINL"
     PFAM_domain     15664..15969
                     /aSDomain="DUF2500"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10694.11"
                     /description="Protein of unknown function (DUF2500)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg34_18_0017"
                     /evalue="5.40E-16"
                     /label="ctg34_18"
                     /locus_tag="ctg34_18"
                     /protein_end="114"
                     /protein_start="12"
                     /score="59.1"
                     /tool="antismash"
                     /translation="VFLTFVFAVVVILISLLYGFSVFLKNKKALLESEDATVISKKNVN
                     NTSFISNYFLNNTSFLVVFKMDSKADKKFMVSKKIYDSLEINEKGILNYKGTKFIEF"
     CDS             16070..16693
                     /locus_tag="ctg34_19"
                     /transl_table=11
                     /translation="MPKKELREFVKVQLNPHVTKEVTLSLDTGYFGYYSTLIKDWYCES
                     GNYQIFVGSSTYSCSLKGGIYVNNPERPQPDFRITAPDYYALSNNEFKVSREEFEAIYG
                     KRRHIRDVQASRPYTSENTIEDISHTFLGKFIRRYANKVAKDVTESAKEQEGMMASMIG
                     EMPFFTMVASGDGMLSEGMLEGVLHRLNAHYLKGLWKLLKEIRK"
     PFAM_domain     16073..16234
                     /aSDomain="Fn3-like"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14310.8"
                     /description="Fibronectin type III-like domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg34_19_0018"
                     /evalue="3.20E-11"
                     /label="ctg34_19"
                     /locus_tag="ctg34_19"
                     /protein_end="55"
                     /protein_start="1"
                     /score="43.3"
                     /tool="antismash"
                     /translation="PKKELREFVKVQLNPHVTKEVTLSLDTGYFGYYSTLIKDWYCESG
                     NYQIFVGSS"
     CDS             16777..17205
                     /locus_tag="ctg34_20"
                     /transl_table=11
                     /translation="MDISIRYEKPCAEDYVSLRLRSGMGNKNMERCRKALGNSIFTVSI
                     YDNEKLIGFGRIVGDEGITYVVSDIMVDENYRRMGFADEIMKAIDNYFEENTFEDSYIC
                     LIANYPADLLYNKYNFEYLPDNKCGMLRRQNPRENRRE"
     PFAM_domain     16885..17136
                     /aSDomain="Acetyltransf_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00583.27"
                     /description="Acetyltransferase (GNAT) family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg34_20_0019"
                     /evalue="2.40E-08"
                     /label="ctg34_20"
                     /locus_tag="ctg34_20"
                     /protein_end="120"
                     /protein_start="36"
                     /score="34.3"
                     /tool="antismash"
                     /translation="GNSIFTVSIYDNEKLIGFGRIVGDEGITYVVSDIMVDENYRRMGF
                     ADEIMKAIDNYFEENTFEDSYICLIANYPADLLYNKYNF"
     CDS             17695..17976
                     /locus_tag="ctg34_21"
                     /transl_table=11
                     /translation="MKGELLLDIAHIDDYNHLEKIIKVKFSKCIHIADKHFNVKHEHLP
                     IGQGELDFEVVFNTCLKGYTGKIIFEVVDTDEEIIKFKSLIQRIFESR"
     CDS             18237..18722
                     /locus_tag="ctg34_22"
                     /transl_table=11
                     /translation="MFYNGKEKGCCNPIINHDQKIISIDGGNVIKSEGQLNALIINGNN
                     FTYHSVDNFPKGIITEDQKGNSNTIQITWMDNAIEVLEEGDEFSFCRHLSSNHELWVKK
                     DKIFKARDGMRCYDCTDYYVPVKKGDIVSIVERATSKTLIKKNGTIGWILNSSINFE"
     CDS             18898..19500
                     /gene_functions="other (smcogs) SMCOG1148:hypothetical
                     protein (Score: 71.1; E-value: 2.4e-21)"
                     /gene_kind="other"
                     /locus_tag="ctg34_23"
                     /transl_table=11
                     /translation="MTLGERLQKLRKERGLSQDQVAEQLDVSRQAVSKWERDEAVPEID
                     KIIALSRIFSVSTDYILKDEVKETIEPRTQLCTTSRFVKFIKTKWYFIGYVVGAWGIWD
                     FANAAIAYITLNSVRDFIGNSNMPITRASQTVSNAADTFIGNGNMPIPFELISVLKIPM
                     TSLWILVVLAAFKIIAGIIITVFGKKHCIKKQSGRTA"
     PFAM_domain     18916..19080
                     /aSDomain="HTH_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01381.24"
                     /description="Helix-turn-helix"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg34_23_0020"
                     /evalue="1.20E-16"
                     /label="ctg34_23"
                     /locus_tag="ctg34_23"
                     /protein_end="61"
                     /protein_start="6"
                     /score="60.5"
                     /tool="antismash"
                     /translation="LQKLRKERGLSQDQVAEQLDVSRQAVSKWERDEAVPEIDKIIALS
                     RIFSVSTDYI"
     CDS             19697..19885
                     /locus_tag="ctg34_24"
                     /transl_table=11
                     /translation="MGNNSINHSTYTTYYTTFQLENGRRLEFCLKGKEYGMLAEGDIGS
                     LTFQGTIYISFERQGIY"
     PFAM_domain     19706..19867
                     /aSDomain="DUF2500"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10694.11"
                     /description="Protein of unknown function (DUF2500)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg34_24_0021"
                     /evalue="6.90E-19"
                     /label="ctg34_24"
                     /locus_tag="ctg34_24"
                     /protein_end="57"
                     /protein_start="3"
                     /score="68.4"
                     /tool="antismash"
                     /translation="NSINHSTYTTYYTTFQLENGRRLEFCLKGKEYGMLAEGDIGSLTF
                     QGTIYISFE"
     CDS             19952..20353
                     /locus_tag="ctg34_25"
                     /transl_table=11
                     /translation="MSISKDNIIFIIYVINQEKSRLFYEKLLGYKPVLDVPGMTEFQLF
                     DSVKLGIMPTEGIMKILENKIPDPSQAKGIPRSEIYMFVDNPEDYYARLVSAGGKGISK
                     CELRNWGDYAAYGSDLDGNIIAFAKKASE"
     CDS             complement(20552..20845)
                     /locus_tag="ctg34_26"
                     /transl_table=11
                     /translation="MFTLNLSDEDIVMKITTRKPVTNKDVAANFIGNMLTRAGGDIADK
                     VNLILTKDSIYLKYRGHASIGYGEETRDIKKIPLEEVIKFSVTPKEKEELIK"
     CDS             complement(21139..21390)
                     /locus_tag="ctg34_27"
                     /transl_table=11
                     /translation="LVQHPISYKDLYVNCNLRSVIIHYKSFFYFYLTNSKIFLTVLAFL
                     IVILLYKEDPTTFDHLVLEKFFIGADQKIIKIIFLLFI"
ORIGIN
        1 agctacgcta tttgctttgc taggagttat agtttatggc ggtgtaaagc ttaattggga
       61 tttggaagaa accgctgctg tgtttatgtg gatgggtatt ttggctggta tatttgcagg
      121 ttttggacca agtaagattg ctaaatatat ggtagatggt gctaagaaaa tgataggagc
      181 agcactgata ataggacttg cccgatctgt ttctgggata ttgaccgcag ggaaaataat
      241 ggatacatgc atttatggaa tggctcaggt tttaggactg ttaccagctt atgtacaggg
      301 aatggcaatg tatatagcaa accttataat gaatgtattt ataacatcag gtagcggact
      361 tgctaatact gtaatgcctt tgtttgtgcc tttagcagat ttagtaggac ttacaagaca
      421 gtcagcagta ttagccttca actttggtga tggcttcgga aactatgttt tgcctacatc
      481 atcagcgctt atgggtatac tgggagctgc caatataccc tatgacagat ggatgaaatt
      541 tatgtggaaa ctattcctta tatgggttgc agttggatct gctttaatgg tagttgcaca
      601 aatcataaaa tttggtccta tgtaaggaga gataaaattg aagcaaagct tatataaaaa
      661 tattaatgat agaagtaaca aattaattgc tatggctgac tatatttttg ataacccgga
      721 gattgcattt aaggagtata aggctagtaa attgatttca gattacttaa aagagcaggg
      781 atttaaagtg gagctaggtt taggaagtct ggatacggca tttaaagcag tgtatgaaaa
      841 tggacaggga ggccctaaca taggcctttt gtgtgaatat gatgcactac ctatgggaca
      901 tggctgtgca catcatatgc agggtccttc tattattgga gcggcagctg caataaaagc
      961 actgtacaat aagaagcctt ataaattaac agtatacgga actcctgcgg aagaaggcgg
     1021 aggagggaag ataaagatga taaatgaggg ctatataaag gaattggatg tagcacttat
     1081 gatgcatggt ggacctgcta ctcaagtaga tgttaaatct ttagctgcca gcagcataaa
     1141 agtgatttac catggaagga gtgctcatgc tgcattaaaa ccagagcaag gcagaagtgc
     1201 cttggatgca ttattattaa ccttccaggc tgtggaattc ttaagagaac acgttcaaga
     1261 ggatacaaaa atgcactaca cagtgattga tgcaggtgga ccaaataacg tagtacccaa
     1321 aactgcctcc ggctctttca gtttgagatc ttataattca tcatatctaa aatctgtaat
     1381 agaacgtttt gaagatatag taaaaggcgc cgcactgatg acaggaacta catatgaaat
     1441 tataagagag aaagatttag acagtaaagt tcctgtatac tctttaaatg atttggttat
     1501 gaataatgca gaacttataa atgctcctaa cattaaaccg gcaagacaaa agaccggatc
     1561 ttcagatttc ggtaatgtga tgtatattat accgggatcc tgcataagaa cgtctttcgt
     1621 tgatgaaaat gcttcctccc actcacaaga atttttagat gatggcaaaa ctcaaagagg
     1681 acatgaagct ataataaatg cagctaagat attagcggga actgtttttg atcttattga
     1741 taatcctagc cttctacgtg aagtaaaaca ggaatttaat gatacaaagg ctaagatgag
     1801 cgtagataat taatattaat tagtgtgttt tagaatccct caaactttaa gtttgaggga
     1861 ttcttctgta gtagtgaata tattatgtag tttgtgtttg aaactgctgt tcagcagctt
     1921 ctgcctcagc catggtaaca tgaactgtac cttttggatg ttgagggggg gaatatatag
     1981 agtataattt aattggttca tgacctgtat ttattaaatt gtgccattta ccagcgggga
     2041 tgatgaaggc gaaatcttca taaaccctct cttgaaaaat caaataatct cttctatccc
     2101 ccattctgat aataccttca ccttgctcta gtcgtacaaa ttgatctagg ttaggatgaa
     2161 tttctaaacc tgtatctcct ccaacaggta tgctcattaa ggtaagctgt aaatggtttc
     2221 ctgtccataa tgcagtacga aaattattgt tttgtaaagt agcatcctcg atattaacta
     2281 caaagggttg tggaccataa tctttaagtt caattctcca aagctctgag ttacttcgag
     2341 gcatattggg aaagtgagga ggagtgctat aataattata cataatgtct aaattatatt
     2401 gaggaatatt catgtaataa gggtacattt gataaggagt gtacatattc tcattccttt
     2461 atagaattac aatatcatca tatgatggtt gctcactgga tgtgctgtat catttttaaa
     2521 atatactgcc tacataggtg gtatataaat aactattaca aaccttacat caactgtaag
     2581 tgttaattgg tgatttaatg ttgtatggta ttaatagaaa aaagtgaggg aggatatgta
     2641 atatgaatat ttctgataaa ctgcttcaag ttcagggagt atataagact tatggtgagg
     2701 gacaaagtga aacagctgct ttaaagggaa ttacttttga tgtccttcct ggagaatttc
     2761 ttggaataat gggtgcgagc ggatctggga agactacact gcttaactgt attgcaacca
     2821 tgctaaaacc tacttctggc cagatacttt tggagaacca gaatatttct tcgtttaaag
     2881 gatctcagct tgcaaaatat agaggtagta aaattggata tttatttcaa gaatttgagc
     2941 ttttagataa tttaactgcc agagaaaata tactattgcc actgttaata catggggaga
     3001 actctaaaaa tcaggagtta cagcttcaaa ggctggttga gcaatttgat ataggagagg
     3061 tattaaataa atttccatct caaatgtcag gaggtcagaa gcagagagtt gcagcggcaa
     3121 gagcattgat ttccaatcca agcattgtat tggcagatga gccaacggga gctttagata
     3181 caaaaaatgc aaaaagtttg atggaaaaat tatcttcaat aaacaaaaat gagggctcag
     3241 ctatattgat ggttactcac gatgccaatg cagcgagctt ttgttccaga atattattta
     3301 ttcaagatgg tgtaattttt catgagctta gaaagaaagt accggtggaa aacagggatt
     3361 ccttttatga gcgtatctta actgttatgg cacagttggg aggaggcagc agtaatgttc
     3421 tttaatttta ttaaaagaaa cagccgtaag gtcagaaaag aaaatggtgt ttattttgcc
     3481 tcactgatta tttctatagt tgccttttat gtgatacttt ctcttggaga tcaagatgtt
     3541 atggtgtatc ttaaaaccgt agagagcgat gcagtggaaa agcttatgct gatgattcca
     3601 atgctttacg gtctttcgtt attcttcgtg tattttctgg tttattttgc aaacagatat
     3661 caattgcagc gtcgtaatca tgaatttggt atttatttaa tgatggggat gaaaagaagc
     3721 aaactctttg cgatgattgt aggggagact ttatggaatg gcctggttgc cctctttatt
     3781 ggaattccca tttctatatt tctaacagag ctgattagta tggctacttc caggcttatt
     3841 ggaatgggaa tcattggtca tgaatttaga atctcctgga ttgggattgg attaacggta
     3901 ttgggattta tcatggtaca gctgggagcc gtatttattt taagcttaaa aatgagcagg
     3961 aaggaacctg tagagctcct taatgaaggc aaggaaaaag ttcaaaaatt aatatctcct
     4021 aaatggggag tgattagttt cctgcttgga gcagttttac tttgtacagc ttatatatta
     4081 gcactcttat atctgaaaaa cctggatttt aagatgtttg gattaatact tataatagga
     4141 atcagcggta cttttatgct ttttagagga ttaggaagtt tgattggagc atggataaaa
     4201 agtaagagca gatattctca agggctattt atatttacag gaaggcagct ccaagagaat
     4261 gttctgcatc aatggaactc tcttgcaatt tcctcgctgt taattcttat ggcaatggtt
     4321 tgctttgctt acggtatttc tacaacttta aatcgtggtg cagcatctgc aagaaccgta
     4381 gattttacct ttaaaggttc agaagaagaa attactgctg tgcttacctc tgataagctg
     4441 aagccctacg tagaggatta ttatgttatg aagataggac attttagaac caaatataga
     4501 gagaaacctg aaaaatcaac ccaacatacc ttttcatggg caggattgaa agagtccatt
     4561 tccagagaag aagattcaga agaaaaagac tttctattaa gagatttgtc ttatagggat
     4621 agtccttatt tgatttctct ttcaagttat aatgcattgc ttaattccat gaataaatcc
     4681 cctattatat taagggagaa tgaagccgca atgtattctt atgcagaatt ttcaaagtct
     4741 catgatatac tgaggaaggt gctgcagtcc aatccaacag taaagattgg agaaaaacaa
     4801 tataaattgg catcggagct atatactagc aatattgttg cagacagagc tataactctt
     4861 tcctatgcat tgattgttcc tgatgaagtc tataactcct ttgcttacat atctaaagat
     4921 tcagtactct ggaacatgac tatagattct gaatttataa aggaaaaggg acttatgcag
     4981 gcaatgaatg aagtggataa gcttttaaaa aactcaggct tacactatga aagctatctt
     5041 tccagcatgg gaagacagat tttttacatg gttgcaggaa gctataccac attgtattta
     5101 agcttgatgt tccttattat tgcaaacact gttttgggat tgaagtttct tatgcagcaa
     5161 agaagtacta gaagtagata tccaacagta tctgtgctag gggggcacgg gttgaagatc
     5221 tccgttcatc agcaagagta caaatctggt ggtatttcgg tttagttatt tcagtagcat
     5281 tggttagttc tattttcgga atcccttcca tgatgggagc ttttttgatt gttccaaagg
     5341 gattagatgt aaaaataagt actattactt ttgcagtagg gcttgctctt tcagccttta
     5401 tagtttttga actatgctat atatggatga tacagaggaa gagtgatgaa gaaataaata
     5461 aattaaaaga aattaaatag gagatgaaaa agtggaaaag atagtgattg ttgaggacga
     5521 cgtttttctt cgtgaagaga tacaaaatat attagaaaaa gagggatact ttgtagaatg
     5581 tatctcttcc tttgatagta tcttcgaaga tattgacact atttcacctt ctttaattat
     5641 attggattta aatttaccta atctttccgg gtttgatatg tgtcgtggac ttaaggtgag
     5701 agggatagga cctattttag tactaacttc acgtaatcag cttaaagatg agcttcatgc
     5761 actggattta ggtgcagatg attatttaac gaagccctgt catcctaaaa gacttatagc
     5821 cagaatccaa aagctgattc acctttattc aaatttgaat gttgtgctgg atgccggtga
     5881 ttttcagctg gatgaaaatg ctaatatact gtatgctggt aagaattttg ttttattaac
     5941 tgataatgaa ggaattataa tgaaagctct agtgaaggct gcaccttcag ttgtgaaaaa
     6001 ggaagagttt tttaggcttc tgtggggaag cagcgactat gtggatgaaa atatactgca
     6061 ggtaaatatg acaagattac gtaagaccct tgagaaagcc ggacttttta atagaatcag
     6121 aactgttaga ggagttgggt atcaattaac gggaggtgat tctaaatgaa gcttaaagat
     6181 tggcttaata ttataaggga aacacatcct tggatactaa ttatctgcat aagtgatgct
     6241 ttttttattt ttttagcttg gctggcttat ccggagaact ttaaaatttt agtggctact
     6301 atgatcatat tttctgtact aagcattgca acaggaattt tattggtgag gaaaaggcag
     6361 gaaaagaagg acaaggcctt ttatgatttt ttgagagaac cttcaatgga gcatgaagga
     6421 gatttaatag attctattgg agaactacat aaagaaaagg taaattactt agctgataaa
     6481 gtaagaacta tgaaggataa attagatgaa accaagctgc aaaatataga ttacgaagag
     6541 tttattgaaa gctgggtgca tgagataaaa actcctattt ccttagcaac tttggttttg
     6601 gaaaatcgta aggaggaaat gtctccattg gtgtatcaaa ggctagaaca tgcaaggatt
     6661 aacatacttg atgatgttga acgaatatta ttttatgcca gactcaaggc ttctcatgtg
     6721 gactataatt tagagaggat atctttagag ctttgctgtg aagatgtgct tttggaactt
     6781 caggcattgc ttgatgaaaa agaagttaaa attatttcta acatgacaga tgtgcccatt
     6841 gtttcagata aaaaggcact tcagtttatt attacgcaga tactccttaa ttcagtgaag
     6901 tactccaaaa aagaaattga gagttttatc cggttaaatt caggttttga tagtattaaa
     6961 aagagatatt atttaaggat ttttgataat ggtattgggg tactgtcttc tgatcttcct
     7021 ttcatttttg ataaaggatt tacaggagat aaccgtagcc acaatcaatc ctcaggaata
     7081 ggactatatc ttgtgaaaaa attatgcgat gaattaaaga ttgaaattga ggtggactct
     7141 gagtatggaa aaggttttac ctttcaattg ctgttccctt taattgagga tatttgaagt
     7201 tttaaaagac taagagtatt taatttataa taaggcagta atagataagc taaaaatatc
     7261 tattactgtt ttttgcgtta aaaagcaaga tgtgtgtgaa taatactaca tacattttaa
     7321 agggaaaaat caatgtataa aataattaga gtaattttaa taagaattat tgactaataa
     7381 taaaataaca agtaaaattg gaaataaata tataaattta cgtataattg ttactttata
     7441 aaatgctgaa tgaaatttgt agttgaaatt tttatataat atttaacaat aacttacctt
     7501 tcctgaagaa tagggtataa attgataaaa agctaatttg ggcattggta agttgtttat
     7561 ataaaaatag aatactaaaa agtcttataa ctttttagta ttcaaatcag ggggtgggaa
     7621 agtaatgcta aagtttagcg gtaaagttgg agctacctgt gttggtagaa cttcaatagt
     7681 catgacacct ggcggatgta catgctgtgc atcttgtaca acaactacaa cttgtacatc
     7741 agcatggtaa tctaaattaa aaagaaatac ataatataac tttcatatta tgtatttctt
     7801 gatttttaaa atttagaaaa gagtgtgttt caatgaatat ggagattttt tttaaccaat
     7861 acctgtaata tgaaatgcag tttttgcggc gcctggaatc aggataatgc aggagaattt
     7921 atagatttag aaaaggtaaa ggaaataata ttacatgcaa gtaaaaaggg atatagatat
     7981 atttcctttt caggtggaga gcctcttcaa tataaatata tatatgatgt tattgaatat
     8041 gctaataatt tggggttttt tatcaattta accacaaacg ggttgctaat tgatgacagc
     8101 tttgttaaga acataggaaa taaaaatgtt aatacccgta tcagttttca ttctcttaat
     8161 aaggatttgt ttaacggcat aactggcagg gagagttcag ataaagtaag ggaatcaata
     8221 caaaggttaa aaaaagaaaa aatagttttt tccataggag ctactatatt tgaagataac
     8281 attaatgagg tacaagctct tgcacagttt gctttagagg aaggtgcaga atacataagg
     8341 tttactccgg tatatagggt ttataaagga agaaatttta atatagatag cattttcttt
     8401 gaaagattgt tattccatat agttaaattt gcattgggaa ataaaaagtc cttacagtat
     8461 aaaaaaagaa cggctttata tttaagtaat tttattaaca ttatcaccac caagcagtgt
     8521 gcagcaggat ctgattatta tattgcagtt aatccggatc ttaatatagt ttcgtgccct
     8581 gttttgcctc actattccgg cagctatact gaaaaatatt cttcttttga aaatattgaa
     8641 agtttaaaag ggtactacaa gaatttactc actaaagagc tggtttctaa tcttaaaggt
     8701 cagtgtagag attgtaagta taagcatacc tgtaagggag gatgcataag tacaaaatta
     8761 gaggagcagc tgtctcttga agaagagcag cctatatgcc ttatgaagat agttaataat
     8821 gttttagata aattatctcc aagggaaatg gaggatatta taagctattg gaaataccaa
     8881 tatgacaaaa aggttatgtt taatgatgat tcatcgggct gcataagaag gctgcccata
     8941 tgggagcttc attttaataa taaatattcc tatgattata agaaataaaa actctgctgt
     9001 aatgtaataa gtgtaaacag gaggcgtaga atggctagta attttaaaaa aaagaaaatg
     9061 actttaaatg aatttatgga aacagaaaca ccgggattga tgagtatttt cgattttgcc
     9121 agtaatcttc ctatatcgct atacgttgat accacagcgg taaagattcc tgaaatatgc
     9181 tattcaagct cattattatc tcaaacacat tttttaagtg agacatatct tttaaataga
     9241 aaaaggaatt cattggattt aggactccaa tatggagtta tggggtattc ttcttttttg
     9301 gtgagaggaa gcatagttca aagaaagctt gcagaagaag aagaactaga aaaggaaaac
     9361 tctgtaatac agcttcctaa atacaaaaac ttaaaaaacc ctttaggagc aaccataaga
     9421 gcaagaagaa gcataaggga aatgactgat aaaagcgttt ctttagaaga tttgtctaca
     9481 atactctttt atggtgatgg agtatccggg gatcttcagt taacttcaga agatgaggat
     9541 attttcccta aaagctcatt aggggaagat tataacggaa ccttaaggac agcaccctcc
     9601 ggaggaggtt tattcccagt taatttatat ttagtaataa gaaaggttaa gggaataaag
     9661 gatgggatat atgtgtatat gcccttaaat cattccctaa aggtaattaa atatttagag
     9721 gaagaggcgg cagaagaatt aaagactgta gttgagtggg gatacaatat agacagctca
     9781 aaaataaatg tgatagtttt ctatgtttat aatttatatg ataattcaag aaagtatctg
     9841 gatatggctt aggattttgc tatgatagaa gcagggcaga tttctcagaa tattcactta
     9901 acagctacag cactgactat agcctcttgc gatgtaggcg gatttgataa gtttaaatct
     9961 gaacaattta tcggtgttga tggcctttct aaaaatatta ttaatgtaac tatattagga
    10021 aattaggggg ggatactatg ggaatcacta aatacatttt agcagaaaac gttgtggttt
    10081 ttaacaatgg agtagatgaa ataagagttc gaagaggtat ttggaattat gaagaggcga
    10141 ttatttctgt agaggggtta actgatacca tgaaggaaat aatcaatgaa atggtgagaa
    10201 ctcttgatat aggtgaagaa cttgatgcag aaaaggtatt gtcagacaaa agattgttgc
    10261 agcatgaaaa ggacagtatt gaaggattag tgttaggttt aaaggagcag ggatatattc
    10321 gagattcaga agaatcaaaa actactcaat tattatatga gatacttaat gggagcatac
    10381 aggcaagatt ccttcaaaat gatatttatt tgaagcctat actgtttttc agtgatagtg
    10441 aagatgtaaa aaattatgct gttgctttgt gtaataagat gagtctcccc atacacgtgg
    10501 tttctgagga agaatataga gaaatcataa aaatggattt aacctccaga ttcgatgggt
    10561 atgaaaccag taaagcagta aaaaagctgg ttaaattcat tgagccctat agctgtctag
    10621 tgggaggact tcaaaaagtc aatgtatcct ttatgagaaa ccttaacagg gcattaatag
    10681 aagcaaataa acctttatct atggctctga tagatggacc ctttactact gtgttcacta
    10741 tcaagcctcc tgaaacagga tgctttgagt gcatggagca aagacttact gcacgaatag
    10801 aggatatgca ggtgtacaga agatttgttg agcatacaag ggggatgaac gtgagtgctg
    10861 taaattccta tgccgctcca ataatgaatt ctatagtatc tactgccata tttgaaggac
    10921 ttataatcag cgcggtaggc aaatctaagc tggcaggcag agcattaaac acctatatac
    10981 ctgtgatgga aattcaggtt gaggatatat taagggttcc cttctgtcca gcctgtggaa
    11041 ccattgcaaa agcaaaaatt gaagaaatgt atacctcaac aaggaagatg gttgataaaa
    11101 tcattgataa catagagctt ggaaattagg aggtacttat atgctgagat attatccctc
    11161 aaatataagg cttaaaaata aatttaaaag tatcaatgca cagcattttg gaataatgga
    11221 atcacagatt cttactacag ctaaaggtaa atattctccg gaagtttcag tttgcactgc
    11281 aaatatgccg gattatcata agataattat agatgagaag gcggagatga accatcattt
    11341 atcaggctac ggtatttatt ttgaagaatc cttgatcaga cttcttggag agggtataga
    11401 aagatatgct cttcttaccg cttcagaaat ttacaaggat aaagaaatta tggctagcta
    11461 caatgaagta agtaaactgg gagaagtgat gccttgggaa tatatagata tgtataccaa
    11521 ggaggattat gacaggctcc tcagctttac aaatatacag aagatagata aggatacaaa
    11581 aataagctgg ataaagtgcc caagtatttt agataaagac cgagaaatat taataccggc
    11641 acaattatta tttataggct ttagaaataa aagggaaaga gaagcgatat ttgcaccagg
    11701 attttcaaag ggagcggctt ctcatgttac tttggaaaat gctctggaat ctgcaatgat
    11761 ggaatcggta gaagcagatg catttacaat taactggtat acctccagaa aaacaagaaa
    11821 gattatagtg gatgatgaaa gtcttttaga aataataata aagactacta aagatattca
    11881 atgtgatgtg ttacctctgg agttttcttt ggaaggaatg cctggtcata cagtaggagt
    11941 agctttaatt aataaaaata ataacaggcc tacggtggtg ttaggctgcc aatctgcatt
    12001 ggatcctaaa aaagctatat ataaagctct tttggaatcc ttagccatac actatttagc
    12061 tgttaatgga ccgctgctgc tgccgaattt gtatttggct tctgtgaaag acaataattt
    12121 taacaatctt gactcaaatg tagctttctg ggctaatcaa tcagatattg atatgaagaa
    12181 atcatatttt tatgatttat gtaaagaaga agtgatgctt agctccttag agtgctatga
    12241 aaaagaagac aaggttgaag aaataaggta tataaaagat aaaatcagta aggtgtcaaa
    12301 gtatggtgtg tacctggata taacaccacc ggaggtttct gataaggggt ggaaggtaat
    12361 aagaaccttt tttccggagc ttgttcaaat gagcctgcca agttttccat acagtaatca
    12421 tccaagactt aaggaatatg gaggagtatt aaatgcctta ccacacccag ttccttaaat
    12481 taataattgt tttagctatg gtaatgcttc ccttggggct tggatcaaat gtttcatatc
    12541 ttatcagtac aatgataagg aaaaagacca taggatttaa cctgttaggt atggttctgt
    12601 cttatgggct tatagtaatt ttagtatggt ttgcagggta taaagaggta ttctttttca
    12661 aaaaggcaac attatatttt tatctttttg ctccatttat aggcattacc tgtataggaa
    12721 tagagtattt agcgggagtt ataataaatt ttgtaagttc cggtaaatgg gtgtttaaaa
    12781 tttctattca ttcatcttat tccagggtag agaaaattaa aaaatttgat attttgatga
    12841 ttgtcttatt tgctgttatt gaagagttgc tttatagaca ggtactggtt aatttgctgc
    12901 agataaactt caatataagc gaaatatcac taatattagt gagttctata gtttttgctt
    12961 tcaatcatat taattttggg gcttttgcag cttttcaaaa actgttcagc ggactgatat
    13021 ttacatgtat ttatctatta tcaggctatt caatactagt accagccata gctcatgctt
    13081 cccaaaatct ttctctacta tttgcaagca gggcaggtga gtttaaatga gcagccagct
    13141 tattaagttt gcattattca ttttcttcgc tggagtatat actattgttt ggggtaaaac
    13201 tgtaagcaca ctggtaaaaa gcaagatagt agtgaagatt gcaaaatttt taatgaacta
    13261 ttcaagaatg aaattagatc ccataaggtt tttaattatt tggctcggtt atttatttgt
    13321 aagtattgta ggaacaatag tattttctgt gatttttaaa atcaacatat tagattatat
    13381 acatttgaaa aattataaag aaatattgtt atattcatta attggtttca tagttcagct
    13441 ttctttatcc tctatgatat taactgtaat ttctttgatt aaatctgata taaactggta
    13501 ttcggtaata agtaatataa gctgggtaaa gataagcagt aagcttccta agtggataaa
    13561 gcctctatat cccataagcg gagcattttt tgaagagctt tattttcgtg gctgtatatt
    13621 tataattatt ataactgaat ttaaatttat acatccctta ctagctataa tcctgatttc
    13681 aatccttttt tcagtccagc aggtgcttaa cactgaaaca gtttatcagg ctgtatctat
    13741 gtccgttggt gcagtgtgta tatcagctgt aggctgtatg ttaatattgg caactaatag
    13801 ttttatacca gcattattgt gtcatgaact ttacgtactg ttttatataa aacactaagc
    13861 attgggggga taagatgatt atcgaggtta aaaatttaaa tgttagatat aaggataaaa
    13921 aagcagttaa taatgttagt ttcaatgtta accaaggtga agtatttggt atgattggag
    13981 caaatggagc aggaaaaact actacaatag aatgcattga aggacttaga aataactatg
    14041 acggtgaaat aaagatactt ggcttaagtc caaagaagga tagaaaaaaa ctccacaagc
    14101 ttataggtgt tcagcttcag gaaacttctt atcaggacag gcttaaggtt aaagagatat
    14161 gcaggctttt tgcaagcttt tatgaggaaa aggaagactt tggagctttg gcaaaggagt
    14221 ttggcctcca tgataaatta aacagctatg taggaaaatt atcaggagga caaagacaga
    14281 agctgtcaat aatcctggca ctgatttcaa agcctaaggt aatttttttg gatgagctta
    14341 caacaggatt agacccaaag tctaggaagg atatgtggga aactgtttta accttaaaaa
    14401 atagggggat aaccatatac ttaactaccc attttatgga ggaagcagag tacttatgtg
    14461 acagagtggc tataatgaag gaagggaaaa tagctgccct tgatactgtg gataatttaa
    14521 aaaataatca cggattactt gataaagtga gctttctttg taatgaaggg ataaacaaag
    14581 atgcattaat gaattttgaa agtgtaaaag aggtcgctga taagaataat tattttacaa
    14641 ttagctgcga tgcagatggt tttttaaagg aattaaatca gtatgtaatg gagaatcatt
    14701 gtatcattat gaatactgaa gttaaaaaac cgagtttaga ggatgttttc tttaaatata
    14761 ccggtgatac actagaaaac gtggaggatt aataatggaa gcatttggtg aaatgataaa
    14821 aacggagttt aaatgtttta cacgtaattt tattaatatg ttttttgttt tggcatttcc
    14881 ggggctattt ttaatactct ttggagagat atatggtaat gatcccagcc ctctctttaa
    14941 tgggcaggga accattgatg catctgtacc tgcttatatt gggatgataa ttgcagtcac
    15001 aggaattatg tcactacctt tggcattagc tagctatagg gaaaagaaga tattaaagag
    15061 atttaaagcc acacctataa gtccttttca tatattagtt tctcaaatta tagttaattt
    15121 aattatgaca ataatcggtg gaggattatt aatattaatt ggaaaagtgg ggtatgattt
    15181 aaccttcagc ggaaaggttt tgccattgat tttagttatt ctcttatcaa taatttgcat
    15241 tttttcaata ggctttctaa ttgcaagcgt ggtgaatgga acaaaagcag caaatgccgt
    15301 tgcaaatctg gtgtactttc caatgctgtt tttaacagga gcaaccttac ccttagaaac
    15361 tatgccggat aagataaaaa aagtatctga attactgcca ttaacacatt gtattaagat
    15421 gatgaaaggt ctgtggcagg ggagcagcat aactgatttt ggcagtgaaa ttatgatagt
    15481 tgcaggtgtt actatagttt gcagcttact atccattaag ttttttagat gggactaaaa
    15541 gctgttatca agttagatgt atgtattaat taatagatta atatagtttt ttctgggaag
    15601 gaaaaagcta ttaaaggtat atgaaacttg agaaggagtg atgtttttta tatgaagata
    15661 attgtttttt taaccttcgt ttttgcggtg gtagttattc ttatctctct cctatacgga
    15721 tttagtgtgt ttctgaaaaa caagaaagca cttttagaat cagaagatgc cactgttatt
    15781 tctaaaaaga atgttaataa cacttcattt atatcaaatt actttttaaa caataccagc
    15841 tttttagttg tgtttaagat ggattcaaaa gcagacaaaa agtttatggt ttcaaaaaaa
    15901 atctatgatt cattagaaat taatgaaaaa ggcattctta attataaagg aacaaaattt
    15961 atagagttta taaaaagcgg aattaacctt taaaattaca aataacggag atttacctag
    16021 gaaggaaaca gccttcatat ttgtttctca tgataataaa accgtattta tgcctaaaaa
    16081 agagctgagg gagtttgtaa aggtgcagtt aaatcctcat gtgacaaaag aggttacttt
    16141 atctcttgat acaggctact ttggatacta cagtacctta attaaggatt ggtactgtga
    16201 aagcggaaac tatcagatat ttgtaggctc ctccacatat agctgcagtc ttaagggagg
    16261 tatatatgtt aacaatccgg aaagacctca gccagatttc agaataacag caccagatta
    16321 ttatgctctt tcaaataatg agtttaaagt ttcaagggag gaatttgaag caatctatgg
    16381 aaaaaggcgt catataaggg atgtacaggc atccagacca tatacttcag agaataccat
    16441 agaagatata agtcatacct tccttggaaa atttattaga cgctatgcaa acaaagtagc
    16501 caaagatgtg actgagagtg caaaggagca ggagggaatg atggcttcaa tgattggaga
    16561 aatgcctttt tttaccatgg tagcctccgg tgatggtatg ctttctgaag gtatgctgga
    16621 aggagtattg catcgcctta atgcacatta ccttaagggg ctgtggaagc ttttaaaaga
    16681 gataagaaaa tagtatgtgg tataattatt ctttcaatca tacctttaat tcaatacatt
    16741 atgtagagaa ttaactttcg tataaggaga ttttacatgg atataagtat tagatatgaa
    16801 aagccctgtg cagaggacta tgtgagtttg agacttcgtt caggtatggg aaataagaat
    16861 atggagaggt gcagaaaagc tttgggaaat tctatattca cagtgtccat ctatgataat
    16921 gaaaagctta ttggttttgg aagaatagta ggagacgaag gtataaccta cgtggtaagc
    16981 gatattatgg tggatgaaaa ttacagaaga atgggatttg ccgatgaaat aatgaaagcc
    17041 atagacaatt actttgaaga aaacactttt gaagacagct atatatgcct tatagccaac
    17101 tatcctgctg atttgttata taataaatat aattttgaat acttgccgga taataagtgt
    17161 ggaatgcttc gaagacaaaa cccaagagaa aatagaaggg aataagataa tattttttat
    17221 taaaacctgc tagattaatt gattttacag ttaatctagc aggctttatt tgtttttagg
    17281 aaaatataat aatataaatg ttaactatag atgtttggtt tttctacttt agtaatagta
    17341 ttcctaataa aagaactggt aaaaatccaa gaattaaata aagcaatccg aatttataag
    17401 gtattaagtt atacaaactt tgtattatta tagaaaatat attaaaatat gtaatacaat
    17461 taatgcaaat gcatagattg atgaaagatg tgatacagtc atatttttta gaaacgaagg
    17521 gcaatgaaat cacagttgtg tataagtaat ttaataatta tttaatatca atatcgtggg
    17581 gaaagggtgt tagtaatgat tgaatatggt agaagtataa ggtggtttaa cgactataga
    17641 gatgagatag cgttttcgga cttgcacaaa tttagtttta tgcagatctg gtttatgaaa
    17701 ggagagctgc ttcttgatat tgctcatatt gatgattaca accatctgga gaagattatt
    17761 aaagtgaagt tttctaaatg tattcatatt gcagataagc attttaatgt aaaacatgaa
    17821 catcttccta taggacaagg tgagcttgac tttgaggtgg ttttcaacac ttgtctaaaa
    17881 ggatatacgg ggaaaataat atttgaagta gttgacacag atgaagaaat tataaaattt
    17941 aaaagtttaa tccaaaggat atttgaaagc cgataaatct ttaaaatcgt ataagagtta
    18001 aaatgtctat aatatttatt ttcttataaa tacctacttt attttgtatg atttccttga
    18061 taagtctact ttaaacagga tttaacataa tcaataggta catccattct cgcagcagtt
    18121 tcttcaattg acataccgct gtctaagaat cttctgacaa ccataagcat attttcacca
    18181 acttcaataa tatgcatatc cggatcatag aaacgaataa cacgctgtcc ccaaggatgt
    18241 tctataatgg gaaggaaaaa ggctgctgta accccattat aaatcatgat caaaagataa
    18301 taagcattga tggaggaaat gttattaaat cagaaggcca gctgaatgct ctaataatta
    18361 atggaaataa ttttacttac cacagtgttg ataactttcc taaaggtatt attacagaag
    18421 accagaaagg taattcaaat acaatacaga taacctggat ggataatgct atagaagtat
    18481 tagaggaagg ggatgaattc agtttctgca gacatttatc ctctaatcat gagctttggg
    18541 tcaaaaagga taagattttt aaagctagag acggtatgag gtgttatgac tgtacagatt
    18601 attatgtacc ggtgaaaaaa ggtgacatag tttcaattgt agaaagagca actagtaaaa
    18661 cactgataaa aaagaacggt acaattggat ggatactaaa tagttcaatt aattttgaat
    18721 aatatgtaat ttataattat cttattaaga ataaataact tgataatatt tataagctat
    18781 ttcttaaaat tattaagctg caacccacag ttgcgaactt tccaagtata gatgctggat
    18841 tgcaacctgc attacagcta atataaagac ataaataacc ttgaagggag aaattatatg
    18901 acgctaggag aaagattaca gaagctcaga aaggaaaggg ggttgtctca ggatcaggtt
    18961 gcagagcagt tggatgtttc aaggcaggca gtttcgaaat gggaaaggga tgaggctgtg
    19021 cctgaaatag ataaaatcat agccttaagc agaattttct cagtaagtac tgattatatt
    19081 ttaaaggatg aggttaagga gaccattgaa ccacgaactc aattatgtac tacgtcacgt
    19141 tttgtaaaat ttattaaaac aaagtggtat tttataggct atgtggtagg tgcatggggg
    19201 atctgggatt ttgcgaatgc tgccattgca tatataactc ttaacagcgt aagagatttt
    19261 atcggaaaca gtaatatgcc tataacacga gcatcacaaa ctgtaagcaa tgctgccgat
    19321 acctttatag gaaatggaaa tatgccaata ccttttgaat taattagtgt acttaaaatt
    19381 cctatgacct ccttatggat attagtagtg ttagcagctt tcaagataat tgccggaatt
    19441 attataactg tttttgggaa aaagcactgc attaagaaac aaagtggaag gacagcatga
    19501 atatgaataa tagatttttt ttaatgggta ttcaagtata gttcaacttg tatttttatt
    19561 ttttataatt attataatca tgataattgt aaagttaatt aagggttttg cggaatggat
    19621 tagaaataat aattcgccaa gaataaatgt acaagcaacc gttattgcta agcgagatat
    19681 gatatcacat aataatatgg gaaataattc cataaaccat tctacttata caacctacta
    19741 cactaccttt caattggaaa atggcagaag actagaattt tgtttaaagg gtaaagaata
    19801 tggaatgctt gcagagggag atattggaag tcttacattt cagggtacaa tatatatatc
    19861 atttgaaaga caaggcatat attaaaaaat gaaaataaaa gtgatatgta taaattgaaa
    19921 tgtttaatag tgaaggaaaa aaggtgattt tatgagtatt tccaaagata atattatatt
    19981 tataatttat gtgatcaatc aggaaaaaag taggttgttt tatgaaaaac tattagggta
    20041 taaacctgtt ttagatgttc ccggaatgac agaatttcag cttttcgaca gtgttaagct
    20101 aggtataatg cctacagaag gaatcatgaa gattcttgaa aataaaatcc ctgatccatc
    20161 tcaggcaaag ggaataccta ggagtgaaat atatatgttt gttgataatc cggaagatta
    20221 ttatgcaagg ttagtttctg caggaggaaa gggaatcagt aagtgtgaac ttagaaattg
    20281 gggagattat gcagcttatg gctctgactt agatggtaat ataattgcct ttgcaaagaa
    20341 agcttctgaa taaaaggtgt ttacttttaa ttaatttgaa gaaaaaggaa atacaaggag
    20401 ctgcattctc ccttttagta cacagtaatc aatgaaggtt tagatttata aaaggcttat
    20461 ttaagatctt ttattacatt tgccatggct agagccaagt tgtcattatt agagttatcc
    20521 ctaataaagt ctagctcctt ttcattagta actattttat taattcttct ttttctttag
    20581 gagttactga aaattttatt acttcctcta agggtatctt ttttatatct ctagtttctt
    20641 ctccatatcc tatggatgcg tggcctctgt attttaagta aatagaatcc ttagttaata
    20701 tgagatttac cttgtcagcg atatctccgc cagctcttgt gagcatgttg cctataaaat
    20761 ttgcggcaac atccttattt gttactggct ttctggttgt aattttcatt acgatatctt
    20821 catcgcttaa atttaaagta aacatcaaac acctcctgta tttatataat tattaattgt
    20881 acttataatt atattccaaa acattccaga gatatactgc cataaattta catagcatta
    20941 atgcttattg ggtaattatt gacatataat aacttataat tttagttttg ataataagga
    21001 tcttttatga aagtgagtgg gtatattatg ggaaggtata tttctatgtt aaggggggaa
    21061 atgtaggagg aaaaatagaa tacctatgga ggagttaaaa aagatctttg aagaaaatga
    21121 cttcatggat atagtaacct atataaacag cagaaatata atttttataa ttttttggtc
    21181 agctccaata aaaaactttt caaggacaag gtggtcaaag gtagttggat cttccttata
    21241 taatagtata acaatcagaa acgccaatac agttaaaaag attttggaat ttgttaaata
    21301 aaaataaaag aagcttttat aatgaataat aacactacgc aaattacaat tgacatacag
    21361 atccttatag ctaatgggat gctgcaccaa agtaacgaat tgcttttgct ctgggctaca
    21421 ataccattct tgcaggggat gggaacagta tctatgatac agattactta aaggctcaac
    21481 ataccattga gcatcataac aatgtactta gtgggattaa ccttaacatt agatgtattt
    21541 aaattgattt ccattttgtt ctatagctcc tggattattt gattaacctt aacaataggt
    21601 atgcttaaat tcaacaaggt tgctggtagt tttttaatta agcgattaaa ctatataaca
    21661 agatgaaata aatgtatatt gttctaattt gtataaaata taacaaagtt atcttgttta
    21721 tttacctaaa taggatataa ttgaattgca tagcaaatct tcacagcaaa taaaaaacta
    21781 tacaatacag tataaataag gctaatatca tataagatac aggtataata aaagtcttat
    21841 aaagacataa aaatatttgt ttgtgaagat atatttttaa caatatcgga ggtattaaaa
    21901 tgtcgaaagt tttctcgtca ctagctcttg gtaatttaaa atcgaaaaac agatttatga
    21961 tggcacctat ggaaaatgga ttagctgaag taggtggtga agtaagccag aggcttattg
    22021 acttctttgc agaaagagca agaaatgaag tttctataat cattaccgga tcaataggta
    22081 tatcccctga gggaagaggt cttccaactc agttaagcat ttatgatgat aaattcgtac
    22141 cgggtttgaa aaggttgacg gatgcaatac ataacgaagg tggaaaaatt ggagctcagc
    22201 tttaccatgc tggtagacaa gcttctgagg cagtaacagg aattcagcct atagcaccaa
    22261 ctgccatgcc ttgtgcaatt cttgggaata atcctaggga aatgacatcg gaggattttg
    22321 cagatataaa agagaagttc aagaaggggg cagaaaggtc tatagaagca ggttttgacc
    22381 ttgtagaagt acattttgct catggatatc tccttcatag cttcttatct ccacacagta
    22441 ataaaagaac agatgaatac ggtggttctt tagaaaac
//
