LOCUS       NZ_LS483338.1          11865 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_LS483338.1 Streptococcus pyogenes strain NCTC12064 chromosome 1,
            complete sequence.
ACCESSION   NZ_LS483338
VERSION     NZ_LS483338.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 12:58:57
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1360393
            Orig. end    :: 1372258
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11865
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[1365393:1367258]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..6865
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..11865
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11865
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="4"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             1059..1214
                     /locus_tag="ctg1_1290"
                     /transl_table=11
                     /translation="MTIGHSKQNLHKKEALKHKKTKNKALFLPSGDSAIKSVISMTVRL
                     LLDDQS"
     CDS             complement(1562..2008)
                     /locus_tag="ctg1_1291"
                     /transl_table=11
                     /translation="LEVSSEVAVSASQPEELHRLPNRLIPEEDNNKLSRVAKEVVTEPR
                     LNNPFLLPKKVLSLEDDAAILNHLEEDRDVNKLFLEPVAAEAKREINFHPSDQQVTAKV
                     KESSDFHQKQHQTGITYGDDTLADLTHHLLHSDGVIPSLNDKSA"
     CDS             complement(2053..3120)
                     /locus_tag="ctg1_1292"
                     /transl_table=11
                     /translation="MMLRDVKVKTSSLLVGCAATLLVSLSSTVAADSVHSSDRRFGVGY
                     KEETTSQFSSDQPSQVVLYRGEANTVRFAYTNQMSLMKDIRIALDGSDKSLTAQIVPGM
                     GHVYEGFQTSARGIFTMSGVPESTVPVANPNVQTKYIRYFKVIDDMHNTMYKGTVFLVQ
                     PQAWKYTMKSVDQLPVDDLNHIGVAGIERMTTLIKNAGALLTTGGSGAFPDNIKVSINP
                     KGRQATITYGDGSTDIIPPAVLWKKGSVKEPTEADQSVGTPTPGIPGKFKRDQSLNEHE
                     AMVNVEPLSHVVKDNIKVIDEKSTGRFEPFRPNEDEKEKPASDVKVRPAEVGSWLEPAT
                     ALPSVEMSAEDRLKS"
     CDS             complement(3374..3775)
                     /locus_tag="ctg1_1293"
                     /transl_table=11
                     /translation="MRNILRFLGIVIISAVILFSIGSFYDLPLMKNIQLICWSFILDLF
                     VFVYKQRQTTEVLTWYQVVKQFWLFIKCTILIPTLIAFIIIIGCLTSISEVSIYFYLHL
                     TVVCYTIGMILSLGRLISPNHSIFNKLKK"
     CDS             complement(3954..4250)
                     /locus_tag="ctg1_1294"
                     /transl_table=11
                     /translation="MKTLDIIFNLSDRKMIFLENVEKLGGYIVPFTLIILSVAYNFRHP
                     YPIWAAVLGGISLIVIFIYFILIVYLYLRYRYLVWKKIPEIKINSTELSCNHI"
     CDS             complement(4300..4494)
                     /locus_tag="ctg1_1295"
                     /transl_table=11
                     /translation="MEVLKNGLAIINGGGKDGANIFLTGMAGAAQGVTVCAQTGVFIPW
                     QGYILCGAAGAATNIIWPH"
     CDS             complement(4788..4988)
                     /locus_tag="ctg1_1296"
                     /transl_table=11
                     /translation="MTTMKELTINDMASISGGNAPGDAVIGGLGGLASGLKFCKLPHPV
                     LAGGCVVGFTVGGAYLGYTAN"
     aSDomain        complement(4890..4976)
                     /aSDomain="TIGR03949"
                     /aSTool="tigrfam"
                     /description="bact_IIb_cerein: class IIb bacteriocin,
                     lactobin A/cerein 7B family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1296_0037"
                     /evalue="1.80E-05"
                     /identifier="TIGR03949"
                     /label="ctg1_1296"
                     /locus_tag="ctg1_1296"
                     /protein_end="33"
                     /protein_start="4"
                     /score="22.4"
                     /tool="antismash"
                     /translation="KELTINDMASISGGNAPGDAVIGGLGGLA"
     aSDomain        complement(4935..4979)
                     /aSDomain="TIGR01847"
                     /aSTool="tigrfam"
                     /description="bacteriocin_sig: bacteriocin-type signal
                     sequence"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1296_0038"
                     /evalue="1.10E-03"
                     /identifier="TIGR01847"
                     /label="ctg1_1296"
                     /locus_tag="ctg1_1296"
                     /protein_end="18"
                     /protein_start="3"
                     /score="17.5"
                     /tool="antismash"
                     /translation="MKELTINDMASISGG"
     CDS             complement(5001..5228)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1297"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 1.8e-16,
                     bitscore: 56.9, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIKKLETFHQMTIEKLAKVEGGKNNWQANVSGVIAAGSAGAAIG
                     FPVCGVACGYIGAKTAITLWAGVTGDTGGF"
     PFAM_domain     complement(5004..5213)
                     /aSDomain="Bacteriocin_IIc"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10439.11"
                     /description="Bacteriocin class II with double-glycine
                     leader peptide"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1297_0103"
                     /evalue="3.40E-12"
                     /label="ctg1_1297"
                     /locus_tag="ctg1_1297"
                     /protein_end="75"
                     /protein_start="5"
                     /score="46.3"
                     /tool="antismash"
                     /translation="LETFHQMTIEKLAKVEGGKNNWQANVSGVIAAGSAGAAIGFPVCG
                     VACGYIGAKTAITLWAGVTGDTGGF"
     aSDomain        complement(5160..5204)
                     /aSDomain="TIGR01847"
                     /aSTool="tigrfam"
                     /description="bacteriocin_sig: bacteriocin-type signal
                     sequence"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1297_0039"
                     /evalue="4.70E-03"
                     /identifier="TIGR01847"
                     /label="ctg1_1297"
                     /locus_tag="ctg1_1297"
                     /protein_end="23"
                     /protein_start="8"
                     /score="15.5"
                     /tool="antismash"
                     /translation="FHQMTIEKLAKVEGG"
     CDS             5547..6053
                     /locus_tag="ctg1_1298"
                     /transl_table=11
                     /translation="MTQFTTELLNFLAQKQDIDEFFRSSLEIAMNDLLQVELSAFLGYE
                     PYEKEGYNTGNSRNGTYSRQFETKYGLVNLIIPRDRNGEFSPVLLPSYARRDDHLEEMV
                     IKLYQTGVTTREISDIIERMYGHHLFLSGSLVIKRSWHHLKRRKISLLSINSHITFGLA
                     FTLQT"
     PFAM_domain     5565..5930
                     /aSDomain="Transposase_mut"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00872.20"
                     /description="Transposase, Mutator family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1298_0104"
                     /evalue="4.60E-40"
                     /label="ctg1_1298"
                     /locus_tag="ctg1_1298"
                     /protein_end="128"
                     /protein_start="6"
                     /score="137.8"
                     /tool="antismash"
                     /translation="ELLNFLAQKQDIDEFFRSSLEIAMNDLLQVELSAFLGYEPYEKEG
                     YNTGNSRNGTYSRQFETKYGLVNLIIPRDRNGEFSPVLLPSYARRDDHLEEMVIKLYQT
                     GVTTREISDIIERMYGHH"
     CDS             complement(6423..6605)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1299"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 2.7e-07,
                     bitscore: 27.5, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDNFLELQFEELVNISGGKGNIGSAIGGCLGGMLIAAAGGPITGG
                     AAAFVCVASGIAAYQ"
     aSDomain        complement(6462..6596)
                     /aSDomain="TIGR03949"
                     /aSTool="tigrfam"
                     /description="bact_IIb_cerein: class IIb bacteriocin,
                     lactobin A/cerein 7B family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1299_0040"
                     /evalue="3.40E-16"
                     /identifier="TIGR03949"
                     /label="ctg1_1299"
                     /locus_tag="ctg1_1299"
                     /protein_end="48"
                     /protein_start="3"
                     /score="56.8"
                     /tool="antismash"
                     /translation="FLELQFEELVNISGGKGNIGSAIGGCLGGMLIAAAGGPITGGAAA
                     "
     CDS             complement(6620..6865)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1300"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 8.4e-16,
                     bitscore: 54.7, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKFVEEIQKEELFHIIGGYSATDCKNHLIGGITSGAIAGGVGAG
                     MATLGVGGVAGAFAGAHVGAIAGGLTCVGGMLFNGK"
     PFAM_domain     complement(6677..6853)
                     /aSDomain="Bacteriocin_IIc"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10439.11"
                     /description="Bacteriocin class II with double-glycine
                     leader peptide"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1300_0105"
                     /evalue="2.20E-12"
                     /label="ctg1_1300"
                     /locus_tag="ctg1_1300"
                     /protein_end="63"
                     /protein_start="4"
                     /score="46.9"
                     /tool="antismash"
                     /translation="VEEIQKEELFHIIGGYSATDCKNHLIGGITSGAIAGGVGAGMATL
                     GVGGVAGAFAGAHV"
     CDS             7263..7517
                     /locus_tag="ctg1_1301"
                     /transl_table=11
                     /translation="MSGLFYHKSYFFKSEQVYDLLNEIRMRYPHAHIILIGNHINYEEI
                     FKNHYRVFGVIDTTSHKSLKSIRDQIQLYLDELYNSNNG"
     CDS             complement(7823..8299)
                     /locus_tag="ctg1_1302"
                     /transl_table=11
                     /translation="MPQDYISYIRSKVGHDKIILNFAGGILTNDDGKVLMQLRGDKKTW
                     AIPGGTMELGESSLETCKREFLEETGIEVEAVRLLNVYTHFEEVYPNGDAVQTIVFIYE
                     LTAVSDMAIDNFHNEETLKLQFFSHEEIAELESVSAKHRLMLEEYFSDSFAMGH"
     PFAM_domain     complement(7865..8233)
                     /aSDomain="NUDIX"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00293.30"
                     /description="NUDIX domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1302_0106"
                     /evalue="1.10E-18"
                     /label="ctg1_1302"
                     /locus_tag="ctg1_1302"
                     /protein_end="145"
                     /protein_start="22"
                     /score="67.6"
                     /tool="antismash"
                     /translation="AGGILTNDDGKVLMQLRGDKKTWAIPGGTMELGESSLETCKREFL
                     EETGIEVEAVRLLNVYTHFEEVYPNGDAVQTIVFIYELTAVSDMAIDNFHNEETLKLQF
                     FSHEEIAELESVSAKHRLM"
     CDS             complement(8319..9215)
                     /gene_functions="other (smcogs) SMCOG1227:ribosome
                     biogenesis GTP-binding protein YsxC (Score: 116.6; E-value:
                     2.8e-35)"
                     /gene_kind="other"
                     /locus_tag="ctg1_1303"
                     /transl_table=11
                     /translation="MFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKIMG
                     IYTTETEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVETVLFMVPADEKRGKGDDMI
                     IERLKAAKIPVILVINKIDKVHPDQLLEQIDDFRSQMDFKEVVPISALEGNNVPTLIKL
                     LTDNLEEGFQYFPEDQITDHPERFLVSEMVREKVLHLTQQEVPHSVAVVVESMKRDEET
                     DKVHIRATIMVERDSQKGIIIGKQGAMLKKIGKMARRDIELMLGDKVYLETWVKVKKNW
                     RDKKLDLADFGYNEKEY"
     PFAM_domain     complement(8370..8606)
                     /aSDomain="KH_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07650.19"
                     /description="KH domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1303_0108"
                     /evalue="9.50E-23"
                     /label="ctg1_1303"
                     /locus_tag="ctg1_1303"
                     /protein_end="282"
                     /protein_start="203"
                     /score="79.9"
                     /tool="antismash"
                     /translation="EVPHSVAVVVESMKRDEETDKVHIRATIMVERDSQKGIIIGKQGA
                     MLKKIGKMARRDIELMLGDKVYLETWVKVKKNWR"
     aSDomain        complement(8388..9203)
                     /aSDomain="TIGR00436"
                     /aSTool="tigrfam"
                     /description="era: GTP-binding protein Era"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1303_0041"
                     /evalue="2.10E-105"
                     /identifier="TIGR00436"
                     /label="ctg1_1303"
                     /locus_tag="ctg1_1303"
                     /protein_end="276"
                     /protein_start="4"
                     /score="349.9"
                     /tool="antismash"
                     /translation="GFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKIMGIYTT
                     ETEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVETVLFMVPADEKRGKGDDMIIERL
                     KAAKIPVILVINKIDKVHPDQLLEQIDDFRSQMDFKEVVPISALEGNNVPTLIKLLTDN
                     LEEGFQYFPEDQITDHPERFLVSEMVREKVLHLTQQEVPHSVAVVVESMKRDEETDKVH
                     IRATIMVERDSQKGIIIGKQGAMLKKIGKMARRDIELMLGDKVYLETWVK"
     aSDomain        complement(8724..9203)
                     /aSDomain="TIGR00231"
                     /aSTool="tigrfam"
                     /description="small_GTP: small GTP-binding protein domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1303_0042"
                     /evalue="1.70E-31"
                     /identifier="TIGR00231"
                     /label="ctg1_1303"
                     /locus_tag="ctg1_1303"
                     /protein_end="164"
                     /protein_start="4"
                     /score="107.2"
                     /tool="antismash"
                     /translation="GFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKIMGIYTT
                     ETEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVETVLFMVPADEKRGKGDDMIIERL
                     KAAKIPVILVINKIDKVHPDQLLEQIDDFRSQMDFKEVVPISALEGNNVPTLIKLL"
     PFAM_domain     complement(8853..9197)
                     /aSDomain="MMR_HSR1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01926.25"
                     /description="50S ribosome-binding GTPase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1303_0107"
                     /evalue="3.60E-23"
                     /label="ctg1_1303"
                     /locus_tag="ctg1_1303"
                     /protein_end="121"
                     /protein_start="6"
                     /score="81.9"
                     /tool="antismash"
                     /translation="VAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKIMGIYTTET
                     EQIVFIDTPGIHKPKTALGDFMVESAYSTLREVETVLFMVPADEKRGKGDDMIIERLKA
                     AKIPVILVINK"
     CDS             complement(9335..9742)
                     /locus_tag="ctg1_1304"
                     /transl_table=11
                     /translation="MALHDNNTTKRKWKNRTITSSLEFALTGVFTAFKEERNLRSHLLS
                     ACLACVAGLFFSISAIEWLFLLLAIFLVITLEIVNSAIENVVDLASDYHFSMLAKNAKD
                     MAAGAVLMISGYAVLTGLIIFIPKIWNIFVH"
     PFAM_domain     complement(9368..9673)
                     /aSDomain="DAGK_prokar"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01219.21"
                     /description="Prokaryotic diacylglycerol kinase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1304_0109"
                     /evalue="2.70E-32"
                     /label="ctg1_1304"
                     /locus_tag="ctg1_1304"
                     /protein_end="125"
                     /protein_start="23"
                     /score="110.7"
                     /tool="antismash"
                     /translation="FALTGVFTAFKEERNLRSHLLSACLACVAGLFFSISAIEWLFLLL
                     AIFLVITLEIVNSAIENVVDLASDYHFSMLAKNAKDMAAGAVLMISGYAVLTGLIIF"
     CDS             complement(9723..10220)
                     /locus_tag="ctg1_1305"
                     /transl_table=11
                     /translation="MYIEMIDETGQVSQEIMEQTLDLLNFAAQKTGKEEKEMSVTFVTN
                     ERSHELNLEYRDTDRPTDVISLEYKPETPILFSQEDLAADPSLAEMMAEFDAYIGELFI
                     SIDKAREQSQEYGHSFEREMGFLAVHGFLHINGYDHYTLEEEKEMFTLQEEILTAYGLT
                     RQ"
     aSDomain        complement(9738..10112)
                     /aSDomain="TIGR00043"
                     /aSTool="tigrfam"
                     /description="TIGR00043: rRNA maturation RNase YbeY"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1305_0043"
                     /evalue="1.30E-39"
                     /identifier="TIGR00043"
                     /label="ctg1_1305"
                     /locus_tag="ctg1_1305"
                     /protein_end="161"
                     /protein_start="36"
                     /score="132.7"
                     /tool="antismash"
                     /translation="EMSVTFVTNERSHELNLEYRDTDRPTDVISLEYKPETPILFSQED
                     LAADPSLAEMMAEFDAYIGELFISIDKAREQSQEYGHSFEREMGFLAVHGFLHINGYDH
                     YTLEEEKEMFTLQEEILTAYG"
     PFAM_domain     complement(9744..10175)
                     /aSDomain="YbeY"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02130.19"
                     /description="Endoribonuclease YbeY"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1305_0110"
                     /evalue="1.40E-39"
                     /label="ctg1_1305"
                     /locus_tag="ctg1_1305"
                     /protein_end="159"
                     /protein_start="15"
                     /score="135.0"
                     /tool="antismash"
                     /translation="IMEQTLDLLNFAAQKTGKEEKEMSVTFVTNERSHELNLEYRDTDR
                     PTDVISLEYKPETPILFSQEDLAADPSLAEMMAEFDAYIGELFISIDKAREQSQEYGHS
                     FEREMGFLAVHGFLHINGYDHYTLEEEKEMFTLQEEILTA"
     CDS             complement(10379..10954)
                     /locus_tag="ctg1_1306"
                     /transl_table=11
                     /translation="MDDLTKAIMADEANLSYTERGIFPLYDAPQTARLIIVGQAPGIVA
                     QETKLYWNDRSGIRLRDWLGVDNDTFYHSGLFGIIPMDFYYPGKGKSGDLPPREGFAAK
                     WHPPLRALMPEVELTILVGRYAQDFYLGNKAYKTLTETVRHFEDYLPDYFPLVHPSPRN
                     QLWLAKNPWFEQDLLPILQKRVEAILTK"
     PFAM_domain     complement(10421..10873)
                     /aSDomain="UDG"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03167.21"
                     /description="Uracil DNA glycosylase superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1306_0111"
                     /evalue="1.20E-17"
                     /label="ctg1_1306"
                     /locus_tag="ctg1_1306"
                     /protein_end="178"
                     /protein_start="27"
                     /score="64.4"
                     /tool="antismash"
                     /translation="APQTARLIIVGQAPGIVAQETKLYWNDRSGIRLRDWLGVDNDTFY
                     HSGLFGIIPMDFYYPGKGKSGDLPPREGFAAKWHPPLRALMPEVELTILVGRYAQDFYL
                     GNKAYKTLTETVRHFEDYLPDYFPLVHPSPRNQLWLAKNPWFEQDLL"
ORIGIN
        1 catggatatc ctgattatcg ttggtggata acctttcgct taaaaacaat ccactttggg
       61 gaaaccctta tatttagttt gtaacaggaa aactaataaa tattaaaaag agtgtcagcg
      121 acctagcggc agctttactc ttaagtgcgt ttgctgccat tgacagcaag gtcaaagctg
      181 atgaaacagc aggggcatac cgttatgatg tgtctgaaca aaacacttac tatcaaacta
      241 tcagccccat taaccagcaa cgacctagtg ccactctcga cgaatgaggt gattattatg
      301 gaacccttac ttcatttact tcccaaagtc gtaccagtac ttatacactt ggtagacaaa
      361 gccaacgtat catggttaac agtgatatta cagttaccta tactcttaaa gacaatttgg
      421 tagcccttca taaggaatat aaaacctttg tcaaaaaaat attacagata aaccgatcac
      481 cagtgactac gacaagacta aggttattta taaccattta atcaacgaat acacttacgc
      541 cacaaaataa cttagcacca atcgcaaaac cgtaagcagc atcaacaatc atactcctaa
      601 agctctttat cgtggcaagt gtggtgtttg tcaagcttat gccgtcatgt ttaaagatat
      661 ggcagaagct gcaggcttat cagcttggta tgtgataaaa aaggattgaa tgagcaccat
      721 gcttgaaaca tcgttaccat tcatggtgtt aattcctacg ttgatgctac ctggaatgat
      781 tcagcataca ccacaaggta tttccttgct gaaaaagacg tgaggaatac tgagtaccgt
      841 ttagatagcc agtacaacca cttggctaat gctattttaa ataccagcta ccaaaaaggc
      901 taaactaaca acaactacat ttttcaacta gaaaggccta aacaatgacc aaaaaacagt
      961 tttatcttat cttagctatt agcatactgt gttttattct tgccgtcagc cctaaaccac
     1021 caattcttaa acacactatt gaaaggaaaa ggactgcgat gaccataggc cactcaaaac
     1081 aaaaccttca caaaaaagaa gcccttaaac acaaaaaaac caaaaataag gctctttttc
     1141 ttccaagtgg ggacagcgct atcaaatctg ttattagcat gacagttaga ctcctgttag
     1201 atgaccaatc ttagctctcc taaaatcagt ggacactacc atttcggtag tgttcttttt
     1261 taagctaatc tcatcaccac gctttcttca agctaaaaaa ctgatcatga aagagcaacc
     1321 ccatcaccct aacagcccac tttgcccgca ctttcttaaa aagttaggag aaaacgatat
     1381 accaattatt ttctgatccc agctccctat cattaacaag atgtgtagca cggacctaca
     1441 tacaggtaag ctagagtcat tctcgctatt tcggacaaaa agaggccggt agttccctga
     1501 cctcttcttt atttatcttg taacactcct cttcttagcg agacttacta gcacataatt
     1561 cttaagcact cttatcattt agactaggaa taacaccatc tgaatgaagc aaatgatgcg
     1621 tcagatctgc cagagtatca tctccataag taatccctgt ttggtgctgt ttctgatgaa
     1681 aatcagatga ctccttaact ttagcagtca cctgctggtc acttggatga aaattaattt
     1741 ctctcttggc ttcagccgca actggctcga ggaacaactt attgacatca cggtcttcct
     1801 ccaaatgatt aaggatagca gcatcatctt ctaacgaaag aaccttcttg ggtaacaaaa
     1861 aggggttatt tagccttggc tcagtaacga cttccttggc tactcgtgat agtttattat
     1921 tgtcttcctc aggtatcaaa cggttaggca atcgatgcaa ttcttccggc tgtgaggcgc
     1981 tcacagctac ttcagaagaa acctccaagc cctttcctgt ttgcctgtct aaagcaaccg
     2041 gcaaattatt aactaacttt ttaacctgtc ctcagcgctc atttcaacac taggaagagc
     2101 tgtcgctggt tctagccagc taccaacttc tgctggtctt accttaacat cgctggcagg
     2161 cttctccttc tcatcttcat taggtctaaa aggctcaaac cgccctgttg atttttcatc
     2221 tatgaccttt atattgtctt ttactacatg agacagtggt tcgacattta ccatagcttc
     2281 atgctcgtta aggctctggt ctcgtttgaa tttaccagga ataccaggag tcggtgttcc
     2341 gacagattga tcggcttcag taggctcttt tacggagcct tttttccata aaactgctgg
     2401 aggaataata tccgtagagc cgtccccata agtaatcgtg gcctgcctcc cctttggatt
     2461 aatagatact ttaatattgt ctgggaaagc cccactacct cctgtggtta aaagggcacc
     2521 cgcattttta atgagagttg tcattcgttc aataccagca acgccaatat ggttcaagtc
     2581 atctactggt aactgatcaa cagatttcat ggtgtatttc caagcttgcg gttgaacaag
     2641 aaaaacagtt cctttataca ttgtgttatg catatcatca atgactttga aataccttat
     2701 atatttggtt tgtacattag ggttagcaac gggaacagtg ctttcaggaa ctcctgacat
     2761 cgtaaaaatc cctctagcag aagtttgaaa gccctcataa acatgaccca taccaggaac
     2821 aatctgagcg gtcaaagact tatcagaacc atccaaagca atgcgaatat ctttcatcag
     2881 agacatctga ttggtatagg caaacctaac cgtgttagcc tcacctcgat acaaaaccac
     2941 ttgggagggc tgatccgaag aaaactgaga ggttgtttct tccttatagc caactccaaa
     3001 acgtctatca gacgaatgga ctgaatctgc cgcaactgta ctactcaaac tgactagtaa
     3061 agtagccgca caaccaacta ataaactgct cgttttaact ttaacatctc ttaacatcat
     3121 catgttcctt tcattatttt ttatttagga attcgtcata ctatattttc tcatattagc
     3181 ctaacaaaaa actcgtaatt ctatataaat catataaaat gacgagcttt ggcaaagatg
     3241 agtatagcag gatggaaaac agattgtttc tgaaacttca aaggtatctt cttgtcacga
     3301 actattcttt aattgaatcg gttacactaa actagtccca ttatttaaaa acaaacttta
     3361 aatattattc atttcacttt ttaagtttat taaatataga gtgattagga gaaataagac
     3421 gacctaatga taaaatcatt cctattgtat agcaaacaac agtaaggtgt aaataaaagt
     3481 aaattgatac ctctgatata ctcgtcaaac atcctattat tataataaaa gcaattaagg
     3541 taggaataag aattgtacac ttaataaata accaaaattg cttaacaact tgataccatg
     3601 tgagcacttc tgtcgtttgt ctttgtttgt agacaaaaac gaataaatca aggataaaac
     3661 tccaacagat aagttgtata tttttcatta atggtaaatc gtagaaacta cctatactaa
     3721 atagaatcac tgcagaaata ataacaatac ctaaaaatct taatatatta cgcatatctt
     3781 cacctcctct actctatcgg tagcaaatat aaccgaacaa attattattc ctgttatcag
     3841 agacagttat aactttttta accaattttc aatacgcatt ttgcttttaa ctctttagtc
     3901 tctaaagtta aatatcataa gtactgatat tgtataagtc atccattttc cccttaaatg
     3961 tgattgcatg atagctcagt agaattaatc ttaatttctg gtattttttt ccacaccaag
     4021 tatctataac gcaaatatag ataaacaata agtataaaat aaataaagat cacaataagg
     4081 gatatacctc ctagtacagc agcccaaata ggataagggt gcctaaagtt gtaggctaca
     4141 ctcaagatga taagggtaaa agggacaatg taacctccca gcttttcaac attttctaga
     4201 aatatcatct ttctatcaga tagattaaaa ataatatcta aagttttcat accactcctc
     4261 tactacttat acatcagtga tagatagtca tttatatatt tagtgaggcc agataatatt
     4321 tgtagcagca ccagctgctc cacacaaaat ataaccttgc caagggataa atacgcctgt
     4381 ctgagcacaa actgtcactc cctgcgcagc acctgccatc cctgtcaaaa agatatttgc
     4441 tccgtctttt ccgcctccat ttatgatagc cagaccattt tttagcactt ccatattttt
     4501 gaagtctttt tcattttaat ttcactcttt tgtattttaa aaagctaaga gtgatatcta
     4561 aattcattgg cataatcact attttctttt atcgataaaa acaaataatg acgctaccaa
     4621 agctacgata gataacatgt ttaccgattt ttccgaaagg gataattgat tgaaaattaa
     4681 aaacactaaa tatggtatag atttatcaac atttttttat gaatggcatc aacaatgatt
     4741 aaaaacatta tagacgcatt cataataata aaaatcgtat agatcattta atttgctgta
     4801 tatcccaaat atgctccacc aactgtaaat cctacaacac atccacctgc caatactgga
     4861 tgtggcagtt tacaaaattt caatccagaa gctaagcctc caagaccacc aattacagca
     4921 tctcctggag cgtttcctcc acttatacta gccatgtcat taattgttaa ttccttcatt
     4981 gttgtcatcc tttctttcct ctagaagccg cctgtatctc ctgttacacc agcccaaaga
     5041 gtaatagctg ttttagctcc aatataacca caggctacac cgcaaactgg aaaacctata
     5101 gcagctccag cactacctgc agcgataacc ccactgacat ttgcctgcca attattctta
     5161 ccaccctcaa ccttggcaag cttttctata gtcatttggt gaaatgtttc cagtttcttt
     5221 atctccatat cgaataactt cttttcataa ttcttaaatt tgtctcgttg caacctcgag
     5281 ctagtacaga atatcataaa gaacagtatc atggtttcaa aatcttaaaa ggctgttttt
     5341 catcatgaaa tgtcttttta tcctctctac acttacgctg tgataatagt taattaatta
     5401 agaagtttaa atgataccat tcatgctttt ataaatacct tttaagattt ttgatggtag
     5461 tgtaaaatat cttgtgtaaa cacacaaaaa ggaataaatc ttgtatagta gagttacgac
     5521 acttcactag aaagagattc attcccatga ctcagtttac cacagaatta cttaacttcc
     5581 tagcacaaaa acaagatatt gatgaattct ttcgctcctc tttagaaata gctatgaatg
     5641 acctcttgca agttgaacta tcagcttttc ttggttatga accttatgaa aaagaaggtt
     5701 acaacacagg taatagccgt aatgggactt attctcgtca gtttgaaaca aagtatggct
     5761 tagtcaattt aatcatccca agagatcgaa acggcgagtt ttcaccagtt ttattaccat
     5821 cttatgctag acgagatgac cacttggaag agatggtgat caaactctat cagactggcg
     5881 ttacgacacg cgaaatcagt gacattattg agcgcatgta tggtcaccac ttgtttctga
     5941 gtggaagcct cgttataaaa aggtcatggc atcacttgaa acgacggaaa atctccttac
     6001 tttctatcaa ttcccacatc acatttggtc tagcatttac tctacaaact tgattgaatc
     6061 actcaataaa gaaattaagc gacaaaacaa gaagagagtg gttttcccaa atgaagaagc
     6121 cttagaacga tgtcttgtaa gtattttcga ggactataat attaagttcg gagctcgtat
     6181 tcataaagga ttcggagcat gctttgacac acttgatagt ttatttgact aatattcaaa
     6241 aactctactc ttgtgtttac acaacatttt aatattatta atttgtaata gtacttagta
     6301 agacataaac aaatatcaca attaaaatta ctttacttgc attttctctt acctctttat
     6361 ccttcaaaaa aatttgggaa agtattagac aaattaaacc gagtattata actataatca
     6421 tatcattgat aagctgcaat tccagatgct acacatacaa atgctgccgc acctccagtt
     6481 attggacctc ctgctgcagc tataagcatc ccacctaagc accctccgat agcagatcca
     6541 atatttcctt ttccaccaga aatatttact aattcttcaa actgtaattc taaaaaatta
     6601 tccatttttc acctcaaaat tattttccat taaataacat accaccaacg caagttaatc
     6661 cacccgcaat agcacctaca tgtgcacctg caaacgcacc tgcaactcct ccaacaccta
     6721 aagtagccat acctgctcca acaccacctg caatagcacc tgaagtaata ccaccaatta
     6781 aatgattttt acaatctgta gcactataac ctccaataat atggaacaac tcttcttttt
     6841 gtatttcttc tacaaatttt atcataactt taaaaacctt tctaaaatgt tatattcatc
     6901 ttgttgcaac tttgacaaac taaatatagc atattattat aaaaattttt ttctatgtcg
     6961 tgaatggttg tataaacatc tcaaataaac tttttaacat attagagact gtcaataatg
     7021 ttgtgtaaac acaagagtag agtttttgaa tattagtcaa ataagctatc aagtgtgtca
     7081 aaacatactc cgaatccttt atgaatacga gctccgaact taatattata gtcttcgaaa
     7141 atacttacaa gacatcgttc tcttttagga tatatgatat ctatctatat taactattac
     7201 ctcaagagat actttctaaa aactcaaatt attagtggga aaaacttaga ttataaatac
     7261 aaatgtcagg tttattttat cataaatcat acttttttaa atctgagcaa gtatatgacc
     7321 ttctaaacga aatacgtatg cgttatcctc atgctcatat tattctaatc ggaaatcata
     7381 ttaattacga ggaaatattt aaaaatcatt atcgagtttt tggtgttatt gacacaacaa
     7441 gtcataaatc attaaagtcc attcgagatc aaattcaact ttacttagac gaactttaca
     7501 attcgaataa tggataggca cttcatcaat tcttttagga aatgattctt gtcacccctt
     7561 ccaagtctat tgccacagtt aggttcaact tgcctaagtc atgcatggct aggtggcaat
     7621 tcgtcataac tctaaaacaa atgtttgatg tctgctagta tcaattggaa agaaaatcct
     7681 gttaacattt aacaaaatta ttcagactta atcagaaaaa ttggaagcaa aaaaagagag
     7741 cataagctct cgaaacatcg tctttcaaaa atttttttaa caagccaatc tccaaaaata
     7801 ctccaactgt cctagagagt tcttaatgcc ccatagcaaa gctatcacta aaatattcct
     7861 ctaacatcag gcgatgtttg gctgagacac tctctaactc tgctatctcc tcatgagaga
     7921 aaaactgtaa cttgagcgtt tcctcattat gaaagttatc aatagccata tcagaaacag
     7981 ccgttagttc atagataaag acaatagtct gaacagcatc accgttggga taaacttcct
     8041 caaaatgagt gtaaacattc agtaagcgaa cagcttcaac ctcaattccg gtttcctcta
     8101 agaactcacg tttgcaagtc tctaaagagc tctcacccag ttccatagtg ccaccaggaa
     8161 tagcccaggt tttcttatca ccacgcaact gcatcagcac cttgccgtca tcattggtca
     8221 aaatcccacc agcaaagtta agaataatct tatcatgccc aactttggag cggatataag
     8281 aaatgtagtc ttgtggcata tgatctcgct ttactatgtt agtattcttt ctcattatag
     8341 ccaaaatcag ctaaatcaag ctttttatcc cgccagtttt tcttgacttt gacccacgtt
     8401 tctaagtaga ccttgtcacc taacatgagt tcaatatcac ggcgcgccat ttttccgatt
     8461 tttttgagca tggctccttg tttaccgatg atgatgcctt tttggctatc gcgctccacc
     8521 ataatggttg cacggatatg cactttatca gtctcttcat ctcgcttcat ggattcgaca
     8581 acaacagcta cggaatgtgg aacctcttgt tgcgtcaaat gcagtacctt ctcacgaacc
     8641 atttctgaca caaggaaacg ttctggatga tcagtaatct gatcttctgg aaaatattgg
     8701 aaaccttctt caagattatc agttaataac ttgattaggg ttggcacatt attaccttct
     8761 agggcagaaa ttgggaccac ttctttaaaa tccatttggc tacggaagtc atcaatctgt
     8821 tccaaaagtt ggtctggatg aaccttatca attttgttga taactaaaat aacaggaatc
     8881 ttagctgctt ttagccgctc gataatcatg tcgtcaccct taccacgctt ttcatcggca
     8941 ggaaccatga aaagaaccgt ctcaacttca cgtaaagtac tataagcaga ttcaaccata
     9001 aaatcaccaa gggcggtctt tggtttatga atacctggcg tatcaataaa gacaatttgt
     9061 tctgtttctg tggtgtaaat gcccataatt ttattacggg tggtctgagc cttgtcactc
     9121 atgatggcaa ttttttgccc catgacatga tttaaaaagg tggatttgcc aacatttgga
     9181 cgaccaagaa tggctacaaa gcctgattta aacatagata attacgggcc ttaacggtag
     9241 ggcttcagat caagcttgtc actaagctta accgtcttgt cctttcctta ttctcctatg
     9301 ccatcatcac ataggatagc ccattccttt ctttttaatg aacgaaaata ttccaaattt
     9361 taggaataaa aattataagt cctgtcaaga cagcatagcc agaaatcatc aaaacagcac
     9421 ctgctgccat atccttggca tttttagcta gcatagaaaa gtgatagtca ctagccaaat
     9481 caactacatt ttcaatagca gaattgacaa tttctaaggt aatgaccaaa aaaatggcta
     9541 gaagtaaaaa taaccattcg atggctgaaa tgctaaaaaa taaaccagca acacaagcta
     9601 aacaggcaga caaaaggtga cttctgagat tgcgttcttc cttaaaagct gtgaaaaccc
     9661 ctgtcaaggc aaactccagg cttgaggtaa tggttctgtt tttccatttc cgtttggtgg
     9721 tattattgtc gtgtaaggcc ataagcagtc aaaatctctt cctgtaaggt aaacatctct
     9781 ttttcttctt caagggtgta gtgatcatac ccattaatat gtaagaatcc atgaacagct
     9841 aaaaatccca tttcacgctc aaaagagtgc ccatattctt gggactgctc acgcgccttg
     9901 tcaatagaaa taaacaattc gccaatataa gcatcaaact ctgccatcat ctctgccaaa
     9961 ctaggatcag cagccaaatc ctcttgacta aataaaatag gcgtttctgg cttatattct
    10021 agagaaatca catctgttgg acgatcagta tctcggtatt ctaagttgag ttcatgactt
    10081 ctttcattgg tcacaaaggt cacagacatt tctttttctt ctttgcccgt cttttgagca
    10141 gcaaaattga gcaaatcaag tgtttgctcc ataatctctt gcgaaacttg tcccgtttcg
    10201 tcaatcatct cgatatacat aaggttaatt gttagggaag ggctgcccac ctcatttggt
    10261 atgttgggca cccattatta tctgacagat aatttccctt atcctttcaa tcagcatttg
    10321 ttatttaccc attataccac aagcccctta aaaatgggaa tgctaggtaa atcagggcct
    10381 atttggttag aattgcctcc acacgttttt gcaagatagg taataaatcc tgctcaaacc
    10441 aggggttctt agctaaccac aattggtttc ttggagaagg atgaacaagt ggaaaatagt
    10501 ctggcaagta atcctcaaag tgacggactg tttcagttaa ggttttgtaa gccttgttac
    10561 caaggtaaaa gtcctgagca tagcgaccaa ccaaaatcgt caattcaact tctggcatca
    10621 atgctcttaa tggcgggtgc cacttagccg caaaaccttc tctaggtggt aagtcaccgg
    10681 attttccctt accaggataa tagaaatcca tagggataat gccaaacaat cctgagtggt
    10741 aaaaggtgtc attgtccaca cctagccagt ctcgtaagcg gatgccacta cgatcattcc
    10801 agtaaagttt ggtttcttga gctactattc caggagcttg gccaacaata ataagcctag
    10861 ctgtttgagg agcatcatat aaaggaaaaa tacctctttc ggtataggag agattagcct
    10921 catctgccat aatagctttg gttaaatcat ccatagaatc ctccttaaaa aggccatatt
    10981 aaacatcatc gtaaaggtct tagtgctctt gaccgatcac agggtatttt gtcaagcctg
    11041 gctggtaatc agcttcaacg tcactagcct taggttttag taagtccttc atctcctctg
    11101 aggacgtttc ataagccttg ataatatcag ccacaacagg atgtcggaca acatctttag
    11161 cagagaaata gacaaaatca atctgtttaa tgccttgtaa tttctgagta gcatcaatca
    11221 aaccagactt gacatttcga gggaggtcaa tctgactcgt atctccattg acaatcattt
    11281 tagaattaaa accaagacgg gtcaaaaaca tcttcatttg catgatagtc gtgttttgag
    11341 cctcatctaa gataacaaaa gcgtcatcca gagtacgacc ccgcatataa gctaacggag
    11401 caatctcaat cacatctcgt tccatcaggc gtgtggtttg ttccttgcct aaaatgtgat
    11461 aaagggcatc gtaaaccggt ctgaggtaag gatccacctt ttctttcaaa tcgcctggta
    11521 aaaaacctag gctttcgcca gcttctaccg caggacgcgt caaaataata cgctttacct
    11581 gtcctctttt cagagcagtg actgcaagcg taacagctaa gaaggttttc cctgtccctg
    11641 caggtcctac accaaaaacc acatcatgac gtttgacact atcaacatag gttttttgac
    11701 ctaatgtttt gactcgtatt gccttaccat agttatcttt aatgatttct tcttcataaa
    11761 gcgccataaa ttggtcaatc tgatgagatt ctgccataga taaagctgtc accacatctg
    11821 atgtgttgac caccatgcca cgacccacta gaaccagtag ggctt
//
