LOCUS       NZ_CP020549.1           8860 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP020549.1 Streptococcus pneumoniae strain Hu17 chromosome.
ACCESSION   NZ_CP020549
VERSION     NZ_CP020549.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:01:09
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 679362
            Orig. end    :: 688222
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..270
                     /locus_tag="ctg1_665"
                     /transl_table=11
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIEL
                     MKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     protocluster    1..8860
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[683685:684033](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4324..4671
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..8860
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..8860
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="4"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     PFAM_domain     49..228
                     /aSDomain="DUF910"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06014.13"
                     /description="Bacterial protein of unknown function
                     (DUF910)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_665_0039"
                     /evalue="5.20E-28"
                     /label="ctg1_665"
                     /locus_tag="ctg1_665"
                     /protein_end="76"
                     /protein_start="16"
                     /score="96.9"
                     /tool="antismash"
                     /translation="MKTFYDVQQFLKRFGIIVYMGKRLYDIELMKLELSRIYDAGLMDK
                     LDYLEAEAVLRREHK"
     CDS             270..650
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1163:rhodanese domain-containing protein (Score: 60.4;
                     E-value: 2.4e-18)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_666"
                     /transl_table=11
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNKEFEALIRTGQL
                     IDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLKKQ
                     GFSEIYILSYGLDSWKGKVKTS"
     PFAM_domain     366..632
                     /aSDomain="Rhodanese"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00581.22"
                     /description="Rhodanese-like domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_666_0040"
                     /evalue="1.90E-14"
                     /label="ctg1_666"
                     /locus_tag="ctg1_666"
                     /protein_end="121"
                     /protein_start="32"
                     /score="54.1"
                     /tool="antismash"
                     /translation="NKEFEALIRTGQLIDLRDPAEFHRKHILGARNIPSSQLKTSLAAL
                     RKDKPVLLYENQRAQRVTNAALYLKKQGFSEIYILSYGLDSWKG"
     CDS             739..966
                     /locus_tag="ctg1_667"
                     /transl_table=11
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKESQ
                     LDYKIEKILNILGIVISVVNWIVAIALIFR"
     PFAM_domain     763..957
                     /aSDomain="MpPF26"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07666.13"
                     /description="M penetrans paralogue family 26"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_667_0041"
                     /evalue="2.70E-10"
                     /label="ctg1_667"
                     /locus_tag="ctg1_667"
                     /protein_end="73"
                     /protein_start="8"
                     /score="40.2"
                     /tool="antismash"
                     /translation="LFVGILSIILGLLFPIVGLILGIIGLVLAISYQKESQLDYKIEKI
                     LNILGIVISVVNWIVAIALI"
     CDS             complement(1006..1731)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1154:Pseudouridine synthase (Score: 185.8; E-value:
                     1.1e-56)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_668"
                     /transl_table=11
                     /translation="MRLDNLLAQEKISRKAMKQALLKGEILVDGCPARSLAQNIDTGLQ
                     ELLFQDQIIQGYEHTYLMLHKSAGVVTANKDRELPTVMDLLPSDIQSDKLYAVGRLDRD
                     TTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQTFQKGIVFLDGTICKPA
                     RLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLAEGNY
                     RPLNQKELQIIKNYLEMSR"
     aSDomain        complement(1051..1539)
                     /aSDomain="TIGR00093"
                     /aSTool="tigrfam"
                     /description="TIGR00093: pseudouridine synthase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_668_0015"
                     /evalue="3.70E-41"
                     /identifier="TIGR00093"
                     /label="ctg1_668"
                     /locus_tag="ctg1_668"
                     /protein_end="227"
                     /protein_start="64"
                     /score="138.5"
                     /tool="antismash"
                     /translation="HKSAGVVTANKDRELPTVMDLLPSDIQSDKLYAVGRLDRDTTGLL
                     LLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQTFQKGIVFLDGTICKPARLEIL
                     SASPSLSQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLAEGNYRPLNQ
                     "
     PFAM_domain     complement(1150..1551)
                     /aSDomain="PseudoU_synth_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00849.24"
                     /description="RNA pseudouridylate synthase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_668_0042"
                     /evalue="1.70E-15"
                     /label="ctg1_668"
                     /locus_tag="ctg1_668"
                     /protein_end="194"
                     /protein_start="60"
                     /score="57.6"
                     /tool="antismash"
                     /translation="YLMLHKSAGVVTANKDRELPTVMDLLPSDIQSDKLYAVGRLDRDT
                     TGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQTFQKGIVFLDGTICKPAR
                     LEILSASPSLSQASITISEGKFHQIKKMFL"
     CDS             1893..3734
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190:GTP-binding protein LepA (Score: 649.6; E-value:
                     8.5e-197)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_669"
                     /transl_table=11
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAERA
                     MDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVVDA
                     YEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQLDF
                     PVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLDYNDF
                     VGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAGDLIAV
                     SGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSRKVEERL
                     QAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEVIVKEIDG
                     VKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPARGLIGYST
                     EFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMSIEERGTIFV
                     NPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPRILTLEESLEF
                     LNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     PFAM_domain     1911..2492
                     /aSDomain="GTP_EFTU"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00009.29"
                     /description="Elongation factor Tu GTP binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_669_0043"
                     /evalue="1.80E-54"
                     /label="ctg1_669"
                     /locus_tag="ctg1_669"
                     /protein_end="200"
                     /protein_start="6"
                     /score="184.4"
                     /tool="antismash"
                     /translation="DIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAERAMDSNDI
                     EKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVVDAYEGTMP
                     QTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQLDFPVVYAS
                     AINGTSSLSDDPADQEATMAPIFDTIIDHIP"
     aSDomain        1914..2330
                     /aSDomain="TIGR00231"
                     /aSTool="tigrfam"
                     /description="small_GTP: small GTP-binding protein domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_669_0017"
                     /evalue="1.00E-23"
                     /identifier="TIGR00231"
                     /label="ctg1_669"
                     /locus_tag="ctg1_669"
                     /protein_end="146"
                     /protein_start="7"
                     /score="81.9"
                     /tool="antismash"
                     /translation="IRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAERAMDSNDIE
                     KERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVVDAYEGTMPQ
                     TRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDE"
     aSDomain        1914..3704
                     /aSDomain="TIGR01394"
                     /aSTool="tigrfam"
                     /description="TypA_BipA: GTP-binding protein TypA/BipA"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_669_0016"
                     /evalue="2.30E-294"
                     /identifier="TIGR01394"
                     /label="ctg1_669"
                     /locus_tag="ctg1_669"
                     /protein_end="604"
                     /protein_start="7"
                     /score="975.1"
                     /tool="antismash"
                     /translation="IRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAERAMDSNDIE
                     KERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVVDAYEGTMPQ
                     TRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQLDFPVVYASA
                     INGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLDYNDFVGRIGIG
                     RVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAGDLIAVSGMEDIF
                     VGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSRKVEERLQAELQTD
                     VSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEVIVKEIDGVKCEPFE
                     RVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPARGLIGYSTEFLSMTR
                     GYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMSIEERGTIFVNPGTEVY
                     EGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPRILTLEESLEFLNDDEYM
                     EVTPESIRLRKQILNKAEREK"
     PFAM_domain     2562..2774
                     /aSDomain="GTP_EFTU_D2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03144.27"
                     /description="Elongation factor Tu domain 2"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_669_0044"
                     /evalue="1.90E-13"
                     /label="ctg1_669"
                     /locus_tag="ctg1_669"
                     /protein_end="294"
                     /protein_start="223"
                     /score="50.7"
                     /tool="antismash"
                     /translation="GRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERR
                     EIQEAKAGDLIAVSGMEDIFVGETIT"
     PFAM_domain     3093..3329
                     /aSDomain="EFG_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00679.26"
                     /description="Elongation factor G C-terminus"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_669_0045"
                     /evalue="4.10E-24"
                     /label="ctg1_669"
                     /locus_tag="ctg1_669"
                     /protein_end="479"
                     /protein_start="400"
                     /score="84.5"
                     /tool="antismash"
                     /translation="KCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLV
                     FLVPARGLIGYSTEFLSMTRGYGIMNHTFDQYLP"
     PFAM_domain     3754..3993
                     /aSDomain="DUF3165"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF11364.10"
                     /description="Protein of unknown function (DUF3165)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_670_0046"
                     /evalue="4.20E-33"
                     /label="ctg1_670"
                     /locus_tag="ctg1_670"
                     /protein_end="80"
                     /protein_start="0"
                     /score="113.6"
                     /tool="antismash"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVLS
                     FLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKK"
     CDS             3754..4008
                     /locus_tag="ctg1_670"
                     /transl_table=11
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVLS
                     FLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     CDS             4324..4671
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Lactococcin_972"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_671"
                     /sec_met_domain="Lactococcin_972 (E-value: 2.2e-26,
                     bitscore: 89.2, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LLHCCSRCAFFERKNKMKTKKHRLLALALISSFTLLGAASAAVQY
                     PDGGVWTYGEGSGGGWAFSNYYHGKKYHYSSLVSRWNSHSDKGEAPAGKTSYAWIWTKW
                     GEQVAFYCDYD"
     aSDomain        4372..4659
                     /aSDomain="TIGR01653"
                     /aSTool="tigrfam"
                     /description="lactococcin_972: bacteriocin, lactococcin 972
                     family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_671_0018"
                     /evalue="1.50E-12"
                     /identifier="TIGR01653"
                     /label="ctg1_671"
                     /locus_tag="ctg1_671"
                     /protein_end="112"
                     /protein_start="16"
                     /score="45.6"
                     /tool="antismash"
                     /translation="MKTKKHRLLALALISSFTLLGAASAAVQYPDGGVWTYGEGSGGGW
                     AFSNYYHGKKYHYSSLVSRWNSHSDKGEAPAGKTSYAWIWTKWGEQVAFYC"
     PFAM_domain     4462..4656
                     /aSDomain="Lactococcin_972"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09683.12"
                     /description="Bacteriocin (Lactococcin_972)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_671_0047"
                     /evalue="9.90E-17"
                     /label="ctg1_671"
                     /locus_tag="ctg1_671"
                     /protein_end="111"
                     /protein_start="46"
                     /score="61.3"
                     /tool="antismash"
                     /translation="DGGVWTYGEGSGGGWAFSNYYHGKKYHYSSLVSRWNSHSDKGEAP
                     AGKTSYAWIWTKWGEQVAFY"
     CDS             4742..5275
                     /locus_tag="ctg1_672"
                     /transl_table=11
                     /translation="MKKLFILLSTFFLSFFLAWIIVLRAPQYLYASYDSVSLLRVKKDT
                     QEPTREVFEQELENFANSEQSLIARRIVEPSKDGTTHFTYATYGQGTLPKEFQEASQES
                     RERSDPLNSYLLLSGSLTKEKLADKLGDLGYKASADRKIPPYFLAFRILLNPLILISSN
                     IWLIFLCFSDYHSD"
     aSDomain        5280..6755
                     /aSDomain="TIGR01654"
                     /aSTool="tigrfam"
                     /description="bact_immun_7tm: bacteriocin-associated
                     integral membrane protein"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_673_0019"
                     /evalue="8.70E-175"
                     /identifier="TIGR01654"
                     /label="ctg1_673"
                     /locus_tag="ctg1_673"
                     /protein_end="492"
                     /protein_start="0"
                     /score="580.9"
                     /tool="antismash"
                     /translation="MRAAGIKLFSGQTLLSIMGHSLSTDIKWLLLSALLSFLGGGVVLF
                     SQGLFYPILLATYGFGISFYLLFLLAISILLMLLYLMSLNYKALVPVIKGRLPLKRLMI
                     LTLLCQLVAVFTVGYAVKTGLTSYQRLKELEISKQAWQDRADYYQISFGLGDRGKDTEN
                     QSKWYAFAKEAIEEEQALYVKDNLLHFANPQGKNEQGETLDTYSPDANTLYVSPSYLDK
                     EKVVVDAETKQKLAHLQKGEFILLLPEHLRSREAELKKIFEERLSYYGKSGEEASAPLD
                     YEMKAHVSYLSMGEKRFVYNNGENPVSTQYLTDPILVVFTPTSTGDSFISLSSWSINAG
                     KQLFIKGYESGLELLKKAGIYEQVSYLKEGRSVYLTRYNEVQTETATLILGAIVGIASS
                     LLLFYSVNLLYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFVFGASLFILSSRDLV
                     IGLLTLLVFLASAVLTLYRQAQKESRVSMTIMKG"
     CDS             5280..6761
                     /locus_tag="ctg1_673"
                     /transl_table=11
                     /translation="MRAAGIKLFSGQTLLSIMGHSLSTDIKWLLLSALLSFLGGGVVLF
                     SQGLFYPILLATYGFGISFYLLFLLAISILLMLLYLMSLNYKALVPVIKGRLPLKRLMI
                     LTLLCQLVAVFTVGYAVKTGLTSYQRLKELEISKQAWQDRADYYQISFGLGDRGKDTEN
                     QSKWYAFAKEAIEEEQALYVKDNLLHFANPQGKNEQGETLDTYSPDANTLYVSPSYLDK
                     EKVVVDAETKQKLAHLQKGEFILLLPEHLRSREAELKKIFEERLSYYGKSGEEASAPLD
                     YEMKAHVSYLSMGEKRFVYNNGENPVSTQYLTDPILVVFTPTSTGDSFISLSSWSINAG
                     KQLFIKGYESGLELLKKAGIYEQVSYLKEGRSVYLTRYNEVQTETATLILGAIVGIASS
                     LLLFYSVNLLYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFVFGASLFILSSRDLV
                     IGLLTLLVFLASAVLTLYRQAQKESRVSMTIMKGK"
     PFAM_domain     6456..6755
                     /aSDomain="DUF1430"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07242.13"
                     /description="Protein of unknown function (DUF1430)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_673_0048"
                     /evalue="2.10E-27"
                     /label="ctg1_673"
                     /locus_tag="ctg1_673"
                     /protein_end="492"
                     /protein_start="392"
                     /score="95.4"
                     /tool="antismash"
                     /translation="IVGIASSLLLFYSVNLLYFEQFRRDILIKRISGLRFFETHAQYMV
                     SQFASFVFGASLFILSSRDLVIGLLTLLVFLASAVLTLYRQAQKESRVSMTIMKG"
     CDS             6763..7404
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 176.2; E-value:
                     1.4e-53)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_674"
                     /transl_table=11
                     /translation="MIELKNISKKFGSRQLFSDMNLHFEGGKIYALIGTSGCGKTTLLN
                     MIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLVGK
                     KLKEKEKISLMKQALNRVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILADEPT
                     ASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     aSDomain        6772..7383
                     /aSDomain="TIGR03608"
                     /aSTool="tigrfam"
                     /description="L_ocin_972_ABC: putative bacteriocin export
                     ABC transporter, lactococcin 972 group"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_674_0020"
                     /evalue="7.20E-86"
                     /identifier="TIGR03608"
                     /label="ctg1_674"
                     /locus_tag="ctg1_674"
                     /protein_end="207"
                     /protein_start="3"
                     /score="284.9"
                     /tool="antismash"
                     /translation="LKNISKKFGSRQLFSDMNLHFEGGKIYALIGTSGCGKTTLLNMIG
                     RLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLVGKKLK
                     EKEKISLMKQALNRVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILADEPTASL
                     DPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRV"
     PFAM_domain     6814..7254
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_674_0049"
                     /evalue="1.30E-31"
                     /label="ctg1_674"
                     /locus_tag="ctg1_674"
                     /protein_end="164"
                     /protein_start="17"
                     /score="110.1"
                     /tool="antismash"
                     /translation="SDMNLHFEGGKIYALIGTSGCGKTTLLNMIGRLEPYDKGQIIYDG
                     TSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLVGKKLKEKEKISLMKQALNR
                     VNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILADEPTA"
     CDS             7508..8860
                     /locus_tag="ctg1_675"
                     /transl_table=11
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFED
                     NPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTEVE
                     LAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASDKDT
                     LVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAADFLVL
                     NFNQDLAKDLTSKTEATVIPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPGSHNVE
                     NALATIAVAKLRDVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNILATQKA
                     LSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKAGVAYVEA
                     TDIADATRKAYELAIQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE"
     aSDomain        7538..8842
                     /aSDomain="TIGR01087"
                     /aSTool="tigrfam"
                     /description="murD:
                     UDP-N-acetylmuramoylalanine--D-glutamate ligase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_675_0021"
                     /evalue="9.60E-125"
                     /identifier="TIGR01087"
                     /label="ctg1_675"
                     /locus_tag="ctg1_675"
                     /protein_end="445"
                     /protein_start="10"
                     /score="415.0"
                     /tool="antismash"
                     /translation="KVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFEDNPAAQSLLEE
                     GIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTEVELAYLISEAPI
                     IGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASDKDTLVMELSSFQL
                     MGVQEFHPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAADFLVLNFNQDLAKDL
                     TSKTEATVIPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPGSHNVENALATIAVAK
                     LRDVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNILATQKALSGFDNSKVV
                     LIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKAGVAYVEATDIADATRKA
                     YELAIQGDVVLLSPANASWDMYANFEVRGDLFIDTV"
     PFAM_domain     7856..8377
                     /aSDomain="Mur_ligase_M"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08245.14"
                     /description="Mur ligase middle domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_675_0050"
                     /evalue="4.20E-32"
                     /label="ctg1_675"
                     /locus_tag="ctg1_675"
                     /protein_end="290"
                     /protein_start="116"
                     /score="111.8"
                     /tool="antismash"
                     /translation="ITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASDK
                     DTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAADFL
                     VLNFNQDLAKDLTSKTEATVIPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPGSHN
                     VENALATIAVA"
     PFAM_domain     8435..8641
                     /aSDomain="Mur_ligase_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02875.23"
                     /description="Mur ligase family, glutamate ligase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_675_0051"
                     /evalue="1.00E-09"
                     /label="ctg1_675"
                     /locus_tag="ctg1_675"
                     /protein_end="378"
                     /protein_start="309"
                     /score="38.6"
                     /tool="antismash"
                     /translation="VKHRLQFVDDIKGVKFYNDSKSTNILATQKALSGFDNSKVVLIAG
                     GLDRGNEFDELVPDITGLKKMVIL"
ORIGIN
        1 atgagtctct tcttgaaaaa aacacaaaat tttgctagaa tgagtcttat gaaaacattc
       61 tatgatgtgc agcaattcct caaacgattt ggtattattg tttacatggg aaaacgctta
      121 tatgatattg aactgatgaa gttggaacta tctcggattt acgatgcagg gttgatggat
      181 aaattagact atctagaggc agaagcagtt cttcgcagag agcacaaggt agaattggat
      241 tatattgaga aaaatggaga aaagaactaa tggttacttg gattttgtgg gcacttatac
      301 tagcaatgtt ggcgtggatg ggctttaact atcttcgtat tcgccgtgcg gctaaaattg
      361 tggacaataa ggagtttgaa gccttgattc gtacgggtca attgattgat ttgcgcgacc
      421 cagcagaatt ccacagaaaa catatccttg gtgcacgcaa tattccttca agtcagttga
      481 aaactagtct tgcagcactt cgtaaagata aacctgtcct tctctacgaa aaccaacgtg
      541 cgcaacgagt tacaaatgca gctctttact tgaaaaaaca aggtttttct gagatttata
      601 tcctttctta tggcttggat tcttggaaag ggaaagtgaa gactagctaa ccttatttcc
      661 aaattagtcg aatgatagga tgaagctatt gttttatagt ataattaatt tgtataaaat
      721 ttaaagagtt cttagaacat gaaagaaaag aagaaaaatc cactttttgt gggtatcttg
      781 tcgattattc ttggtttgtt atttccaatt gtaggcctga ttttgggtat cataggattg
      841 gtcttggcta tttcatacca aaaagagtca caattagact ataaaataga aaagattctt
      901 aatatcttag gaattgtgat ttctgtagtt aactggattg tagcaatcgc cttaattttt
      961 cggtaaataa aagaaaaaag ctttagtttt aaagcttttt ttattttatc gactcatctc
     1021 taaatagttt ttaatgattt gtaactcttt ttggttcaaa gggcggtagt taccttctgc
     1081 taaatctggg ttcaatgtga agtccccaaa ttggattctc ttgaggctag tcaccttaac
     1141 accaaccgag aggaacattt tcttgatttg atgaaatttt ccttctgaaa tggtgataga
     1201 ggcttgactg agggaaggac ttgctgatag aatctctagt cttgcaggtt tacagatagt
     1261 gccatctaaa aagacaattc ctttttgaaa ggtttggata tggtcaggtg ttagaagtcc
     1321 attaacctca acttgataag tcttatcgac atgatattgg ggatggagga gttggaagcc
     1381 caagggaccg ttatcggtca agagaaggag tcctgttgta tctcggtcca gtcggccgac
     1441 ggcatagagc ttgtcagact ggatgtcaga tggaagcaag tccatgacgg tcggaagttc
     1501 cctgtcttta ttggctgtaa cgacaccagc agatttatga agcataaggt aggtgtgctc
     1561 atagccttga atgatttggt cctgaaaaag gagttcctgt agtcctgtat cgatattttg
     1621 ggctagggag cgggctgggc aaccatcgac gagaatttcc cctttaagta aggcttgttt
     1681 catggccttt cggctgattt tttcttgggc taataaatta tctaaacgca tactgtgctt
     1741 atcttatcat aagtcgcctg ctttgaaaag gcttgacgtg aaaagaaaag cagagtgaaa
     1801 acatttacac ttgcttgagt tatgttattt acctgaaatt atggtataat cgttcagtta
     1861 gaaaataaat tttgaatatt atagaggaaa tcatgacaaa attaagagaa gatatccgta
     1921 acattgcgat tatcgcccac gttgaccacg gtaaaacaac cctcgttgac gaattattga
     1981 aacaatcaga aacgcttgat gcacgtactg aattggctga gcgtgctatg gactcaaacg
     2041 atatcgaaaa agagcgtgga attaccatcc ttgctaaaaa tacagccgtt gcctacaacg
     2101 gaactcgtat caacatcatg gatacaccag gacacgcgga cttcggtgga gaagttgagc
     2161 gtatcatgaa aatggttgac ggtgttgttt tggtcgtaga tgcctacgaa ggaacaatgc
     2221 cacaaactcg tttcgtattg aaaaaagcct tggaacaaga ccttgtccca atcgtggttg
     2281 ttaacaaaat cgataaacca tcagctcgcc cagcagaagt ggtggacgag gtcttggaac
     2341 ttttcatcga gcttggtgca gatgatgacc agcttgattt cccagtggtt tatgcttcag
     2401 ctatcaacgg aacttcttca ttgtcagatg atccagctga tcaagaagcg actatggcac
     2461 caatctttga cacaattatc gaccatatcc cagctccagt agataactca gatgagcctt
     2521 tgcagttcca agtatcactt ctggactaca atgacttcgt tggacgtatc ggtatcggtc
     2581 gtgtcttccg tggtactgtg aaggttgggg accaagttac cctttctaaa ctagatggta
     2641 caactaaaaa cttccgtgtt acaaaactct tcggtttctt tggtttggaa cgtcgtgaaa
     2701 tccaagaagc aaaagcaggt gacttgattg ccgtttcagg tatggaagac atctttgtcg
     2761 gtgaaaccat tactccgaca gacgcagttg aagctcttcc aatcctacac atcgatgagc
     2821 caactcttca aatgactttc ttggtcaaca actcaccatt tgctggtaaa gaaggtaaat
     2881 gggtaacttc tcgtaaggta gaagaacgtt tgcaggcaga attgcaaaca gacgtttccc
     2941 ttcgtgttga cccaactgat tcaccagata aatggacagt ttcaggacgt ggagaattgc
     3001 acttgtcaat ccttatcgaa acaatgcgtc gtgagggata tgaacttcaa gtatctcgtc
     3061 cagaagttat cgtaaaagaa atcgacggtg ttaaatgtga accatttgaa cgtgtacaaa
     3121 tcgacactcc agaagaatac caagggtctg ttatccaaag cctttctgaa cgtaaaggtg
     3181 aaatgttgga tatgatttca actggtaatg gtcaaactcg tttggtcttc cttgttccag
     3241 cgcgtggttt gattggatac tcaactgagt tcttgtcaat gactcgtggt tacggtatca
     3301 tgaaccatac cttcgaccaa tacttgccat tgattccagg ggaaattggt ggacgtcacc
     3361 gtggtgccct tgtttctatc gatgctggta aggctacaac ttactcaatc atgtctatcg
     3421 aagaacgtgg tacgattttt gtcaacccag gtactgaggt ttatgaagga atgatcatcg
     3481 gtgaaaactc tcgtgaaaat gacttgacag ttaacatcac gaaggcaaaa caaatgacca
     3541 acgttcgttc agctactaag gatcaaacag ctgttatcaa gacgcctcgt atcttgacac
     3601 ttgaagagtc tcttgagttc ttgaacgacg atgagtacat ggaagtaacg cctgagtcta
     3661 tccgtttgcg taaacaaatc cttaacaaag cagagcgtga gaaagctaac aagaagaaaa
     3721 aatcagctga ataagagcta gaaagagaga aagatggtct atttagtcct aggaatttta
     3781 ctgctcctac tctatgtatt tgcgacacca gaaagcatta aagggacagt caatatcgtc
     3841 gctatggtat gtattttagt ggcactcttg attttattgg ttctatcttt tctgaaaatt
     3901 tttcaattac caacagaaat attcctagca atagccatgt tgatcctagc ttactttagt
     3961 gtgagagaca tcacactcat gccagtcaaa aaaagtaaaa gaagataaaa aagagagttt
     4021 cggctctctt tttgctagga attttataat agtttgaatt gctttttagt taacaccatc
     4081 tcttttgctt gtatagtatg aatgggaaaa acttgaataa aattcgttaa tggcatctat
     4141 tttatatttg cttagtactg gttgcatatt attttgaaat aaaactacta tataatatta
     4201 ttcatagagg caatgtagta aaatatctaa aaaattcgat tttttccttg acaacaaata
     4261 ataaaaatgt tattcttatc acataagaaa gcggtttcaa taaaagagag aggagggttt
     4321 attttgttgc attgttgctc aaggtgtgct ttttttgaaa gaaaaaataa aatgaaaacg
     4381 aaaaaacata gattacttgc tctagctctt atttcaagtt ttacattatt gggagctgca
     4441 tcagctgctg tacaatatcc agatggagga gtatggacgt atggagaagg ttcaggaggt
     4501 ggttgggctt tttcaaatta ctatcatggt aaaaaatatc attattcttc tcttgtaagt
     4561 agatggaata gtcattcaga taaaggagaa gctcctgctg gaaaaacctc ctatgcatgg
     4621 atttggacta aatggggaga acaagtagca ttttactgtg attatgacta atcgttcatt
     4681 gatttaaatc gttccccttg taagaaatta cagggggaat tttgtttaca aggagtctac
     4741 tatgaagaaa ctattcatat tattatcaac tttttttctc agcttcttcc ttgcttggat
     4801 tattgtctta cgtgcgccac aatatttata tgcaagctat gattccgttt ctttacttcg
     4861 tgtcaaaaaa gatactcagg aaccgacgcg tgaggtattt gaacaggaat tggagaattt
     4921 tgcaaactca gaacagagtt taatagctag aagaattgta gagccgagta aggatgggac
     4981 gactcacttt acttatgcaa cttatggtca gggaacttta ccaaaagaat tccaagaagc
     5041 tagccaagaa agtcgtgaac gtagtgatcc gctaaatagt tatctccttt tgtcaggctc
     5101 cttgacgaaa gaaaagcttg ccgataaatt aggagatttg ggttataaag caagtgctga
     5161 ccgaaagata ccgccctatt ttcttgcttt tcgaatatta ctaaatcccc ttattttaat
     5221 tagtagcaat atttggctta tctttctttg ctttagtgat tatcactcgg attaaggaaa
     5281 tgagagcagc aggtataaaa ctcttttctg gtcagactct cttatccatc atggggcatt
     5341 ctttatctac tgatatcaaa tggctccttc tatcagccct cctttccttc ctaggtgggg
     5401 gagtcgttct ttttagtcaa ggtttgtttt atcctatctt gttagccacc tatggttttg
     5461 ggattagttt ctatctgttg tttttattgg cgatttcaat tttactaatg ctcctttatc
     5521 taatgagttt gaattacaaa gcattagttc ccgttattaa ggggagatta ccccttaaac
     5581 gcctgatgat tttaacccta ttgtgtcagt tggttgctgt ctttacagta ggatacgctg
     5641 ttaagacagg tttgacgtct taccaacgat tgaaagaact tgaaatttca aaacaagcat
     5701 ggcaggatag agcagactat tatcaaattt cttttggctt aggtgataga ggaaaagata
     5761 cagaaaatca gagcaagtgg tatgcctttg ccaaggaagc aatcgaagaa gaacaagctc
     5821 tttatgtaaa ggataatctg ctccattttg ccaatccaca aggaaaaaat gaacagggag
     5881 agacactgga tacctatagt ccagatgcta atacgctcta tgttagtccc agttatttgg
     5941 acaaggaaaa ggtcgtggta gatgctgaga ccaaacagaa gttagcccat ctccaaaaag
     6001 gtgagtttat cctcttgctc ccagaacatt tgcgctctcg agaagcagaa cttaagaaaa
     6061 tttttgaaga aagattgagt tattatggaa aatctggtga ggaggcaagt gctcctttgg
     6121 attatgagat gaaagcgcac gttagttatc tttcaatggg agaaaagcgg tttgtttata
     6181 ataacggtga gaatcccgta tccactcagt atttgactga tccgatttta gtggtattca
     6241 cgccgacttc tacaggtgat agttttatat ccttatctag ttggtctatc aatgctggaa
     6301 aacaactctt tatcaaagga tatgagagtg ggctagaact cttgaagaaa gctggaattt
     6361 atgagcaagt atcctatctt aaagaaggaa gaagtgttta tctaactcgt tataatgaag
     6421 ttcaaactga aacagcaact ttaatcttag gagctattgt ggggatagct agttccttgt
     6481 tactatttta ttctgtcaat cttctatatt tcgagcaatt ccgccgagat atcttgatta
     6541 aacgaatttc aggtttacga ttttttgaaa cacatgctca gtatatggtt agccaatttg
     6601 ccagttttgt atttggtgct agtctcttta ttttaagcag tcgagacttg gtgattggct
     6661 tgctcacttt attggtcttt ctagctagtg cagttttgac gctttaccgt caagcgcaga
     6721 aagaatctcg tgtttctatg acaattatga aaggaaaata ggatgattga actaaagaat
     6781 atatctaaaa aatttggaag ccgtcagcta ttttcagata tgaatcttca ttttgaaggt
     6841 gggaaaattt atgccttaat cggtacaagt ggctgtggta agacaacact cttgaatatg
     6901 attggacgat tagagccata tgacaaaggg caaatcatat atgatggcac ttctcttaag
     6961 gacattaagc cttctgtttt ctttagagat tacttaggat acttatttca agattttggc
     7021 ttaattgaaa gccaaaccgt caaagagaat ctcaatctgg gtttagttgg taaaaagttg
     7081 aaggaaaaag agaaaatctc tttgatgaaa caagctctaa accgtgtaaa cctctcttat
     7141 ttggatttga agcaacctat atttgagtta tcaggaggag aagcacaacg tgttgcacta
     7201 gcgaagataa ttttaaagga tccacctttg atcctcgcag atgaaccaac cgcttcctta
     7261 gaccccaaaa actctgagga attactttcc atcctagaat ctttaaaaaa tccgaatcgg
     7321 accattatta ttgcgaccca taatcctctg atttgggagc aagtggatca ggtcattcga
     7381 gttaccgatt tatcacatag atgatatggt aagattcagt tagaagaaag agtcacaaac
     7441 acactttgtg gcttttttat ttccataaaa atggtaaaat agtaggagta gaaatggagt
     7501 tcgagacatg aaagtaatag atcaatttaa aaataagaaa gtccttgttt taggtttggc
     7561 caagtctggt gaatctgcag ctcgtttgtt ggacaagcta ggtgccattg tgacagtaaa
     7621 tgatgggaaa cctttcgagg acaatccagc tgcccaaagt ttgctggaag aagggatcaa
     7681 ggtcattaca ggtggccatc ctttggaact cttggatgaa gagtttgccc ttatggtgaa
     7741 aaatccaggt atcccctaca acaatcccat gattgaaaag gctttggcca agggaattcc
     7801 agtcttgact gaggtggaat tggcttattt gatttcagaa gcaccgatta ttggtatcac
     7861 aggatcgaac ggtaagacaa ccacaacgac tatgattggg gaagttttga ctgctgctgg
     7921 ccaacatggt cttttatcag ggaatatcgg ctatccagct agtcaggttg ctcaaatagc
     7981 atcagataag gacacgcttg ttatggaact ttcttctttc caactcatgg gtgttcaaga
     8041 attccatcca gagattgcgg ttattaccaa cctcatgcca actcatatcg actaccatgg
     8101 gtcattttcg gaatatgtag cagccaagtg gaatatccag aacaagatga cagcagctga
     8161 tttccttgtc ttgaacttta atcaagactt ggcaaaagac ttgacttcca agacagaagc
     8221 cactgttata ccattttcaa cacttgaaaa ggttgatgga gcttatctgg aagatggtca
     8281 actctacttc cgtggtgaag tagtcatggc agcgaatgaa atcggtgttc caggtagcca
     8341 caatgtggaa aatgcccttg cgactattgc tgtagccaag cttcgtgatg tggacaatca
     8401 aaccatcaag gaaactcttt cagccttcgg tggtgtcaaa caccgtctcc agtttgtgga
     8461 tgacatcaag ggtgttaaat tctataacga cagtaaatca actaatatct tggctactca
     8521 aaaagccttg tcaggatttg acaacagcaa ggtcgtcttg attgcaggtg gtttggaccg
     8581 tggcaatgag tttgacgaat tggtgccaga cattactgga ctcaagaaga tggtcatcct
     8641 gggtcaatct gcagaacgtg tcaaacgggc agcagacaag gctggtgtcg cttatgtgga
     8701 ggcgacagat attgcagatg cgacccgcaa ggcctatgag cttgcgattc aaggagatgt
     8761 ggttcttctt agtcctgcca atgctagctg ggatatgtat gctaactttg aagtacgtgg
     8821 cgacctcttt atcgacacag tagcggagtt aaaagaataa
//
